Aliases for TOMM40 Gene
External Ids for TOMM40 Gene
Previous GeneCards Identifiers for TOMM40 Gene
TOMM40 is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for protein import into mitochondria (Humphries et al., 2005 [PubMed 15644312]).[supplied by OMIM, May 2008]
GeneCards Summary for TOMM40 Gene
TOMM40 (Translocase Of Outer Mitochondrial Membrane 40 Homolog (Yeast)) is a Protein Coding gene. Diseases associated with TOMM40 include wolfram syndrome 2 and charcot-marie-tooth neuropathy type 2a. Among its related pathways are Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein and Mitochondrial Protein Import. GO annotations related to this gene include porin activity and protein transmembrane transporter activity. An important paralog of this gene is TOMM40L.
UniProtKB/Swiss-Prot for TOMM40 Gene
Channel-forming protein essential for import of protein precursors into mitochondria.