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Aliases for TOMM20L Gene

Aliases for TOMM20L Gene

  • Translocase Of Outer Mitochondrial Membrane 20 Like 2 3
  • Translocase Of Outer Mitochondrial Membrane 20 Homolog (Yeast)-Like 2 3 5
  • Translocase Of Outer Mitochondrial Membrane 20 Homolog Type I 2 3
  • UNQ9438 3

External Ids for TOMM20L Gene

Previous GeneCards Identifiers for TOMM20L Gene

  • GC14P057933
  • GC14P058862
  • GC14P039027

Summaries for TOMM20L Gene

GeneCards Summary for TOMM20L Gene

TOMM20L (Translocase Of Outer Mitochondrial Membrane 20 Like) is a Protein Coding gene. An important paralog of this gene is TOMM20.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TOMM20L Gene

Genomics for TOMM20L Gene

Regulatory Elements for TOMM20L Gene

Enhancers for TOMM20L Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TOMM20L on UCSC Golden Path with GeneCards custom track

Promoters for TOMM20L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TOMM20L on UCSC Golden Path with GeneCards custom track

Genomic Location for TOMM20L Gene

58,395,916 bp from pter
58,417,080 bp from pter
21,165 bases
Plus strand

Genomic View for TOMM20L Gene

Genes around TOMM20L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TOMM20L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TOMM20L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TOMM20L Gene

Proteins for TOMM20L Gene

  • Protein details for TOMM20L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    TOMM20-like protein 1
    Protein Accession:
    Secondary Accessions:
    • B2RPR0

    Protein attributes for TOMM20L Gene

    152 amino acids
    Molecular mass:
    17700 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TOMM20L Gene

Proteomics data for TOMM20L Gene at MOPED

Post-translational modifications for TOMM20L Gene

No Post-translational modifications

Other Protein References for TOMM20L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TOMM20L Gene

Domains & Families for TOMM20L Gene

Protein Domains for TOMM20L Gene

Suggested Antigen Peptide Sequences for TOMM20L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the Tom20 family.
  • Belongs to the Tom20 family.
genes like me logo Genes that share domains with TOMM20L: view

No data available for Gene Families for TOMM20L Gene

Function for TOMM20L Gene

Gene Ontology (GO) - Molecular Function for TOMM20L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity IBA --
genes like me logo Genes that share ontologies with TOMM20L: view

Phenotypes for TOMM20L Gene

MGI mutant phenotypes for TOMM20L:
inferred from 1 alleles
GenomeRNAi human phenotypes for TOMM20L:
genes like me logo Genes that share phenotypes with TOMM20L: view

Animal Models for TOMM20L Gene

MGI Knock Outs for TOMM20L:

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for TOMM20L Gene

Localization for TOMM20L Gene

Subcellular locations from UniProtKB/Swiss-Prot for TOMM20L Gene

Mitochondrion outer membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for TOMM20L Gene COMPARTMENTS Subcellular localization image for TOMM20L gene
Compartment Confidence
mitochondrion 4
cytosol 1
extracellular 1
golgi apparatus 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for TOMM20L Gene

Pathways & Interactions for TOMM20L Gene

SuperPathways for TOMM20L Gene

No Data Available

Gene Ontology (GO) - Biological Process for TOMM20L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016031 tRNA import into mitochondrion IBA --
genes like me logo Genes that share ontologies with TOMM20L: view

No data available for Pathways by source and SIGNOR curated interactions for TOMM20L Gene

Drugs & Compounds for TOMM20L Gene

No Compound Related Data Available

Transcripts for TOMM20L Gene

mRNA/cDNA for TOMM20L Gene

(4) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(8) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TOMM20L Gene

Translocase of outer mitochondrial membrane 20 homolog (yeast)-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TOMM20L Gene

No ASD Table

Relevant External Links for TOMM20L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TOMM20L Gene

mRNA expression in normal human tissues for TOMM20L Gene

mRNA differential expression in normal tissues according to GTEx for TOMM20L Gene

This gene is overexpressed in Testis (x28.4).

SOURCE GeneReport for Unigene cluster for TOMM20L Gene Hs.592307

genes like me logo Genes that share expression patterns with TOMM20L: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TOMM20L Gene

Orthologs for TOMM20L Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TOMM20L Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TOMM20L 35
  • 87.25 (n)
  • 82.55 (a)
-- 36
  • 37 (a)
(Canis familiaris)
Mammalia TOMM20L 35
  • 83.77 (n)
  • 76.32 (a)
TOMM20L 36
  • 53 (a)
(Mus musculus)
Mammalia Tomm20l 35
  • 71.05 (n)
  • 60.53 (a)
Tomm20l 16
Tomm20l 36
  • 60 (a)
(Pan troglodytes)
Mammalia TOMM20L 35
  • 99.34 (n)
  • 98.03 (a)
TOMM20L 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Tomm20l 35
  • 74.05 (n)
  • 63.09 (a)
(Monodelphis domestica)
Mammalia TOMM20L 36
  • 62 (a)
(Anolis carolinensis)
Reptilia TOMM20L 36
  • 38 (a)
fruit fly
(Drosophila melanogaster)
Insecta Tom20 36
  • 26 (a)
tomboy20 36
  • 26 (a)
(Caenorhabditis elegans)
Secernentea tomm-20 36
  • 25 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes TOM20 38
Species with no ortholog for TOMM20L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for TOMM20L Gene

Gene Tree for TOMM20L (if available)
Gene Tree for TOMM20L (if available)

Paralogs for TOMM20L Gene

Paralogs for TOMM20L Gene

(1) SIMAP similar genes for TOMM20L Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TOMM20L: view

Variants for TOMM20L Gene

Sequence variations from dbSNP and Humsavar for TOMM20L Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs56206729 -- 58,398,627(+) AATCA(A/G)TCAAT intron-variant
rs142958493 -- 58,398,306(+) TAGTG(C/T)GGTAG intron-variant
rs146631988 -- 58,398,506(+) TTGTG(A/G)TGGAT intron-variant
rs34340769 -- 58,398,158(+) CAGCT(-/C)CCATG intron-variant
rs35347360 -- 58,398,124(+) ACCTT(-/C)CCCTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TOMM20L Gene

Variant ID Type Subtype PubMed ID
nsv901985 CNV Loss 21882294
esv2748733 CNV Deletion 23290073

Variation tolerance for TOMM20L Gene

Residual Variation Intolerance Score: 64.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.79; 16.56% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for TOMM20L Gene

Disorders for TOMM20L Gene

Relevant External Links for TOMM20L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TOMM20L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TOMM20L Gene

Publications for TOMM20L Gene

  1. Patterns that define the four domains conserved in known and novel isoforms of the protein import receptor Tom20. (PMID: 15733919) LikiA8 V.A. … Lithgow T. (J. Mol. Biol. 2005) 2 3 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TOMM20L Gene

Sources for TOMM20L Gene