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Aliases for TOMM20L Gene

Aliases for TOMM20L Gene

  • Translocase Of Outer Mitochondrial Membrane 20 Homolog (Yeast)-Like 2 3
  • Translocase Of Outer Mitochondrial Membrane 20 Homolog Type I 2 3
  • TOMM20-Like Protein 1 3
  • UNQ9438 3

External Ids for TOMM20L Gene

Previous GeneCards Identifiers for TOMM20L Gene

  • GC14P057933
  • GC14P058862
  • GC14P039027

Summaries for TOMM20L Gene

GeneCards Summary for TOMM20L Gene

TOMM20L (Translocase Of Outer Mitochondrial Membrane 20 Homolog (Yeast)-Like) is a Protein Coding gene. An important paralog of this gene is TOMM20.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TOMM20L Gene

Genomics for TOMM20L Gene

Regulatory Elements for TOMM20L Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TOMM20L Gene

Start:
58,395,916 bp from pter
End:
58,408,701 bp from pter
Size:
12,786 bases
Orientation:
Plus strand

Genomic View for TOMM20L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TOMM20L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TOMM20L Gene

Proteins for TOMM20L Gene

  • Protein details for TOMM20L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UXN7-TO20L_HUMAN
    Recommended name:
    TOMM20-like protein 1
    Protein Accession:
    Q6UXN7
    Secondary Accessions:
    • B2RPR0

    Protein attributes for TOMM20L Gene

    Size:
    152 amino acids
    Molecular mass:
    17700 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TOMM20L Gene

Proteomics data for TOMM20L Gene at MOPED

Post-translational modifications for TOMM20L Gene

No Post-translational modifications

Other Protein References for TOMM20L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TOMM20L Gene

Domains for TOMM20L Gene

Protein Domains for TOMM20L Gene

Suggested Antigen Peptide Sequences for TOMM20L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6UXN7

UniProtKB/Swiss-Prot:

TO20L_HUMAN :
  • Q6UXN7
Family:
  • Belongs to the Tom20 family.
genes like me logo Genes that share domains with TOMM20L: view

No data available for Gene Families for TOMM20L Gene

Function for TOMM20L Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TOMM20L

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TOMM20L Gene

Localization for TOMM20L Gene

Subcellular locations from UniProtKB/Swiss-Prot for TOMM20L Gene

Mitochondrion outer membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TOMM20L Gene COMPARTMENTS Subcellular localization image for TOMM20L gene
Compartment Confidence
mitochondrion 5
cytosol 1
extracellular 1
golgi apparatus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for TOMM20L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005742 mitochondrial outer membrane translocase complex IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TOMM20L: view

Pathways for TOMM20L Gene

SuperPathways for TOMM20L Gene

No Data Available

Interacting Proteins for TOMM20L Gene

Gene Ontology (GO) - Biological Process for TOMM20L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006605 protein targeting IEA --
GO:0006886 intracellular protein transport --
genes like me logo Genes that share ontologies with TOMM20L: view

No data available for Pathways by source for TOMM20L Gene

Transcripts for TOMM20L Gene

mRNA/cDNA for TOMM20L Gene

(4) Additional mRNA sequences :
(8) Selected AceView cDNA sequences:
(4) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TOMM20L Gene

Translocase of outer mitochondrial membrane 20 homolog (yeast)-like:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TOMM20L

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TOMM20L

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TOMM20L Gene

No ASD Table

Relevant External Links for TOMM20L Gene

GeneLoc Exon Structure for
TOMM20L
ECgene alternative splicing isoforms for
TOMM20L

Expression for TOMM20L Gene

mRNA expression in normal human tissues for TOMM20L Gene

mRNA differential expression in normal tissues according to GTEx for TOMM20L Gene

This gene is overexpressed in Testis (28.4).

SOURCE GeneReport for Unigene cluster for TOMM20L Gene Hs.592307

genes like me logo Genes that share expressions with TOMM20L: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for TOMM20L Gene

Orthologs for TOMM20L Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TOMM20L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TOMM20L 35
  • 99.34 (n)
  • 98.03 (a)
TOMM20L 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 37 (a)
ManyToMany
TOMM20L 35
  • 87.25 (n)
  • 82.55 (a)
dog
(Canis familiaris)
Mammalia TOMM20L 35
  • 83.77 (n)
  • 76.32 (a)
TOMM20L 36
  • 53 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tomm20l 35
  • 71.05 (n)
  • 60.53 (a)
Tomm20l 16
Tomm20l 36
  • 60 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TOMM20L 36
  • 62 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tomm20l 35
  • 74.05 (n)
  • 63.09 (a)
lizard
(Anolis carolinensis)
Reptilia TOMM20L 36
  • 38 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta Tom20 36
  • 26 (a)
ManyToMany
tomboy20 36
  • 26 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea tomm-20 36
  • 25 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes TOM20 38
Species with no ortholog for TOMM20L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for TOMM20L Gene

ENSEMBL:
Gene Tree for TOMM20L (if available)
TreeFam:
Gene Tree for TOMM20L (if available)

Paralogs for TOMM20L Gene

Paralogs for TOMM20L Gene

Selected SIMAP similar genes for TOMM20L Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TOMM20L: view

Variants for TOMM20L Gene

Sequence variations from dbSNP and Humsavar for TOMM20L Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs1047497 -- 58,407,493(-) TTTCA(A/C)AAAGA intron-variant
rs2031418 -- 58,405,002(+) TCACT(C/G)TTGTT intron-variant
rs4901855 -- 58,401,309(+) GCTCA(C/T)GCCTG intron-variant
rs6573201 -- 58,403,286(+) ccagg(A/G)gtttg intron-variant
rs7146035 -- 58,394,732(+) gtgac(A/G)caatc upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TOMM20L Gene

Variant ID Type Subtype PubMed ID
nsv901985 CNV Loss 21882294
esv2748733 CNV Deletion 23290073

Relevant External Links for TOMM20L Gene

HapMap Linkage Disequilibrium report
TOMM20L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TOMM20L Gene

Disorders for TOMM20L Gene

No disorders were found for TOMM20L Gene.

No data available for UniProtKB/Swiss-Prot for TOMM20L Gene

Publications for TOMM20L Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  2. Patterns that define the four domains conserved in known and novel isoforms of the protein import receptor Tom20. (PMID: 15733919) LikiA8 V.A. … Lithgow T. (J. Mol. Biol. 2005) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TOMM20L Gene

Sources for TOMM20L Gene

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