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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TOM1L2 Gene

protein-coding   GIFtS: 52
GCID: GC17M017746

Target Of Myb1-Like 2 (Chicken)

(Previous name: target of myb1 (chicken) homolog-like 1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Target Of Myb1-Like 2 (Chicken)1 2
Target Of Myb-Like Protein 22 3
Target Of Myb1 (Chicken) Homolog-Like 11
TOM1-Like Protein 22

External Ids:    HGNC: 119841   Entrez Gene: 1466912   Ensembl: ENSG000001756627   UniProtKB: Q6ZVM73   

Export aliases for TOM1L2 gene to outside databases

Previous GC identifers: GC17U990153 GC17M017693 GC17M017950 GC17M017691 GC17M017688 GC17M017500


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TOM1L2 Gene: 
TOM1L2 (target of myb1-like 2 (chicken)) is a protein-coding gene. Diseases associated with TOM1L2 include smith magenis syndrome, and medulloblastoma. An important paralog of this gene is STAM2.

UniProtKB/Swiss-Prot: TM1L2_HUMAN, Q6ZVM7
Function: Probable role in protein transport. May regulate growth factor-induced mitogenic signaling

Gene Wiki entry for TOM1L2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010718.16  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TOM1L2 gene promoter:
         SRF   HOXA9   AML1a   p53   SRF (504 AA)   LUN-1   Nkx2-5   Evi-1   Arnt   CP2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTOM1L2 promoter sequence
   Search SABiosciences Chromatin IP Primers for TOM1L2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TOM1L2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p11.2   Ensembl cytogenetic band:  17p11.2   HGNC cytogenetic band: 17p11.2

TOM1L2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TOM1L2 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M017746:  view genomic region     (about GC identifiers)

Start:
17,746,822 bp from pter      End:
17,875,784 bp from pter
Size:
128,963 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TM1L2_HUMAN, Q6ZVM7 (See protein sequence)
Recommended Name: TOM1-like protein 2  
Size: 507 amino acids; 55556 Da
Subunit: Interacts with clathrin, SRC and TOLLIP
Sequence caution: Sequence=AAL78338.1; Type=Frameshift; Positions=101, 121, 170;
Secondary accessions: B7Z7F4 Q86V61 Q8TDE7 Q96M88
Alternative splicing: 4 isoforms:  Q6ZVM7-1   Q6ZVM7-2   Q6ZVM7-3   Q6ZVM7-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TOM1L2: NX_Q6ZVM7

Explore proteomics data for TOM1L2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6ZVM7

  • TOM1L2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TOM1L2 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001028723.1  NP_001076437.1  

    ENSEMBL proteins: 
     ENSP00000464297   ENSP00000463313   ENSP00000368818   ENSP00000312860   ENSP00000379088  
     ENSP00000438621   ENSP00000437655   ENSP00000445188   ENSP00000465677   ENSP00000466863  

    Human Recombinant Protein Products for TOM1L2: 
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    Novus Biologicals TOM1L2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TOM1L2 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IEA--

    TOM1L2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/6 InterPro protein domains (see all 6):
     IPR002014 VHS
     IPR004152 GAT
     IPR027429 TOM1L2
     IPR018205 VHS_subgr
     IPR008942 ENTH_VHS

    Graphical View of Domain Structure for InterPro Entry Q6ZVM7

    ProtoNet protein and cluster: Q6ZVM7

    2 Blocks protein domains:
    IPB002014 VHS
    IPB004152 GAT domain


    UniProtKB/Swiss-Prot: TM1L2_HUMAN, Q6ZVM7
    Domain: The GAT domain mediates interaction with TOLLIP
    Similarity: Belongs to the TOM1 family
    Similarity: Contains 1 GAT domain
    Similarity: Contains 1 VHS domain


    TOM1L2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TM1L2_HUMAN, Q6ZVM7
    Function: Probable role in protein transport. May regulate growth factor-induced mitogenic signaling

         Genatlas biochemistry entry for TOM1L2:
    v-Myb target gene-like 2,retroviral oncogene,involved in transformation of myelomonoctic cells,in the
    Smith-Magenis critical region

    Phenotypes:
         15 MGI mutant phenotypes (inferred from 1 allele(MGI details for Tom1l2):
     adipose tissue  behavior/neurological  cardiovascular system  craniofacial  endocrine/exocrine gland 
     hematopoietic system  immune system  integument  nervous system  renal/urinary system 
     reproductive system  respiratory system  skeleton  tumorigenesis  vision/eye 

    TOM1L2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TOM1L2 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TOM1L2 
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    8/40 QIAGEN miScript miRNA Assays for microRNAs that regulate TOM1L2 (see all 40):
    hsa-miR-194* hsa-miR-4254 hsa-miR-642a hsa-miR-520f hsa-miR-301a hsa-miR-519a hsa-miR-548m hsa-miR-1183
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TOM1L2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TOM1L2

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/7 Interacting proteins for TOM1L2 (Q6ZVM73 ENSP000003688184) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TOLLIPQ9H0E23, ENSP000003147334I2D: score=3 STRING: ENSP00000314733
    LAPTM5Q135713I2D: score=3 
    RNF11Q9Y3C53I2D: score=3 
    EGFRP005333I2D: score=1 
    CLTCENSP000002691224STRING: ENSP00000269122
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006886intracellular protein transport IEA--

    TOM1L2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TOM1L2 (TM1L2)

    Search CenterWatch for drugs/clinical trials and news about TOM1L2 / TM1L2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TOM1L2 gene (3 alternative transcripts): 
    NM_144678.3  NM_001033551.2  NM_001082968.1  

    Unigene Cluster for TOM1L2:

    Target of myb1-like 2 (chicken)
    Hs.462379  [show with all ESTs]
    Unigene Representative Sequence: NM_001082968
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000581396(uc002grv.4 uc002grz.4 uc002gry.4 uc010vwy.2 uc010cpr.3 uc010vwz.2 uc010vxa.2)
    ENST00000478943 ENST00000379504 ENST00000318094 ENST00000577794 ENST00000395739
    ENST00000535933 ENST00000540946 ENST00000486413 ENST00000542206 ENST00000468944
    ENST00000577517 ENST00000537091(uc010vxb.2) ENST00000579586
    miRNA
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    8/40 QIAGEN miScript miRNA Assays for microRNAs that regulate TOM1L2 (see all 40):
    hsa-miR-194* hsa-miR-4254 hsa-miR-642a hsa-miR-520f hsa-miR-301a hsa-miR-519a hsa-miR-548m hsa-miR-1183
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Additional mRNA sequence: 

    AF038192.1 AK055959.1 AK057308.1 AK124331.1 AK294846.1 AK295111.1 AK299872.1 AK301944.1 
    AK303305.1 AL133641.1 AY358769.1 BC051650.1 

    18 DOTS entries:

    DT.214806  DT.40317395  DT.101978294  DT.40206939  DT.100791262  DT.120893433  DT.91759435  DT.120893408 
    DT.91893600  DT.97771130  DT.99971568  DT.100791264  DT.120893367  DT.101965419  DT.40268049  DT.75138915 
    DT.91893536  DT.91996847 

    24/181 AceView cDNA sequences (see all 181):

    AL699152 BG152505 AI874411 BU729407 CD672488 F11076 AI079971 BF589523 
    BQ669270 BF436829 BM703482 BX093118 Z39006 BQ670241 T72258 N54155 
    AK057308 BE464966 AA399639 AI191415 CA388796 AI222548 AI423798 BI753590 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TOM1L2 expression in normal human tissues (normalized intensities)      TOM1L2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAAATACTC
    TOM1L2 Expression
    About this image


    TOM1L2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/25 selected tissues (see all 25) fully expand
     
     Epithelium (Uncategorized)    fully expand to see all 4 entries
             vagina ; squamous epithelial cells   
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Leydig Cells Testis Interstitium
             testis ; cells in seminiferus ducts   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 3 entries
             colon ; peripheral nerve/ganglion   
     
     Oral Cavity (Gastrointestinal Tract)    fully expand to see all 2 entries
             salivary gland ; glandular cells   
     
     Thyroid (Endocrine System)    fully expand to see all 2 entries
             thyroid gland ; glandular cells   

    See TOM1L2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TOM1L2

    SOURCE GeneReport for Unigene cluster: Hs.462379

    UniProtKB/Swiss-Prot: TM1L2_HUMAN, Q6ZVM7
    Tissue specificity: Ubiquitously expressed with higher expression in heart and skeletal muscle

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TOM1L2 gene from 8/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tom1l21 , 5 target of myb1-like 2 (chicken)1, 5 87.64(n)1
    94.87(a)1
      11 (37.81 cM)5
    2168101  NM_153080.21  NP_694720.21 
     602267155 
    chicken
    (Gallus gallus)
    Aves TOM1L21 target of myb1-like 2 (chicken) 79.68(n)
    92.11(a)
      416509  XM_414813.3  XP_414813.2 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    83(a)
    68(a)
    possible ortholog
    possible ortholog
    AAWZ02037398(3281-12718)
    GL343977.1(75936-118072)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.14822 Xenopus laevis transcribed sequence with weak similarity more 77(n)    BJ072276.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005356151 TOM1-like protein 2-like 70.78(n)
    76.74(a)
      100535615  XM_003198201.1  XP_003198249.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG35291 CG3529 53.17(n)
    48.18(a)
      39093  NM_140058.2  NP_648315.1 
    worm
    (Caenorhabditis elegans)
    Secernentea C07A12.76
    Protein C07A12.7, isoform b
    44(a)
    1 → many
    X(4517743-4521069)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes GGA2(YHR108W)4 Protein that interacts with and regulates Arf1p and more   --   8(328303-330060) 856508  NP_011976.1 


    ENSEMBL Gene Tree for TOM1L2 (if available)
    TreeFam Gene Tree for TOM1L2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TOM1L2 gene
    STAM22  TOM1L12  TOM12  STAM2  
    4 SIMAP similar genes for TOM1L2 using alignment to 6 protein entries:     TM1L2_HUMAN (see all proteins):
    TOM1    GGA3    TOM1L1    GGA1

    TOM1L2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2177 SNPs in TOM1L2 are shown (see all 2177)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs116528831,2
    C,F,H--17746649(+) ACAACC/ATGGGC 2 -- int15Minor allele frequency- A:0.00NS EA NA 404
    rs65026181,2
    C,F,H--17746741(+) TGGCCG/ACCCCT 2 -- int111Minor allele frequency- A:0.36NA WA CSA 254
    rs575255321,2
    C--17746979(+) AACAC-/ATGACAG 2 -- ut310--------
    rs1391430171,2
    --17747116(+) TATCCA/GTCCCC 2 -- ut310--------
    rs1425585391,2
    --17747127(+) CTCTCC/TGGGAG 2 -- ut310--------
    rs1159015421,2
    C,F--17747204(+) GTGGCC/TGCAGG 2 -- ut311Minor allele frequency- T:0.01WA 118
    rs1162628341,2
    C,F--17747251(+) GGTGAC/TGGGCA 2 -- ut311Minor allele frequency- T:0.03WA 118
    rs1927642651,2
    --17747268(+) GAGGCA/GAGCAC 2 -- ut310--------
    rs31837021,2
    C,F,A,H--17747289(-) CATTGT/CCTGTC 2 -- ut3125Minor allele frequency- C:0.43MN NS EA NA WA CSA 2525
    rs1854316751,2
    C--17747301(+) CTCTGA/GGGTGG 2 -- ut310--------

    HapMap Linkage Disequilibrium report for TOM1L2 (17746822 - 17875784 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/13 variations for TOM1L2 (see all 13):    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv510701CNV Loss20534489
    nsv522668CNV Loss19592680
    dgv3072n71CNV Loss21882294
    nsv907768CNV Loss21882294
    dgv3074n71CNV Loss21882294
    dgv3073n71CNV Loss21882294
    nsv833385CNV Loss17160897
    nsv907766CNV Loss21882294
    nsv907748CNV Loss21882294
    dgv3076n71CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    3 diseases for TOM1L2:    About MalaCards
    smith magenis syndrome    medulloblastoma    dementia


    TOM1L2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TOM1L2
    Human Genome Epidemiology (HuGE) Navigator: TOM1L2 (1 document)

    Export disorders for TOM1L2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TOM1L2 gene, integrated from 9 sources (see all 34):
    (articles sorted by number of sources associating them with TOM1L2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk. (PubMed id 20167577)1, 4 Reynolds C.A....Prince J.A. (2010)
    2. Recruitment of clathrin onto endosomes by the Tom1-Tollip complex. (PubMed id 16412388)1, 2 Katoh Y.... Nakayama K. (2006)
    3. The adaptor protein Tom1L1 is a negative regulator of Src mitogenic signaling induced by growth factors. (PubMed id 16479011)1, 2 Franco M.... Roche S. (2006)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Genes in a refined Smith-Magenis syndrome critical deletion interval on chromosome 17p11.2 and the syntenic region of the mouse. (PubMed id 11997338)1, 2 Bi W....Lupski J.R. (2002)
    7. Transcription mapping in a medulloblastoma breakpoint interval and Smith-Magenis syndrome candidate region: identification of 53 transcriptional units and new candidate genes. (PubMed id 10036180)1, 3 Seranski P....Poustka A. (1999)
    8. Bcl2-associated Athanogene 3 Interactome Analysis Reve als a New Role in Modulating Proteasome Activity. (PubMed id 23824909)1 Chen Y....Ge F. (2013)
    9. Why do cellular proteins linked to K63-polyubiquitin c hains not associate with proteasomes? (PubMed id 23314748)1 Nathan J.A....Goldberg A.L. (2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 146691 HGNC: 11984 AceView: TOM1L2 Ensembl:ENSG00000175662 euGenes: HUgn146691
    ECgene: TOM1L2 H-InvDB: TOM1L2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TOM1L2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TOM1L2 gene:
    Search GeneIP for patents involving TOM1L2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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