Aliases for TOB1 Gene
External Ids for TOB1 Gene
Previous HGNC Symbols for TOB1 Gene
Previous GeneCards Identifiers for TOB1 Gene
This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
GeneCards Summary for TOB1 Gene
TOB1 (Transducer Of ERBB2, 1) is a Protein Coding gene. Among its related pathways are Diurnally regulated genes with circadian orthologs and IL-2 Gene Expression in Activated and Quiescent T-Cells. GO annotations related to this gene include transcription corepressor activity and SMAD binding. An important paralog of this gene is BTG4.
UniProtKB/Swiss-Prot for TOB1 Gene
Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex.