External Ids for TNRC6B Gene
Previous GeneCards Identifiers for TNRC6B Gene
GeneCards Summary for TNRC6B Gene
TNRC6B (Trinucleotide Repeat Containing 6B) is a Protein Coding gene. Diseases associated with TNRC6B include uterine benign neoplasm and reproductive organ benign neoplasm. Among its related pathways are PI3K/AKT Signaling in Cancer and Immune System. GO annotations related to this gene include poly(A) RNA binding and nucleotide binding. An important paralog of this gene is TNRC6C.
UniProtKB/Swiss-Prot for TNRC6B Gene
Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.