External Ids for TNRC6B Gene
Previous GeneCards Identifiers for TNRC6B Gene
GeneCards Summary for TNRC6B Gene
TNRC6B (Trinucleotide Repeat Containing 6B) is a Protein Coding gene. Diseases associated with TNRC6B include Uterine Fibroid and Uterine Benign Neoplasm. Among its related pathways are Cellular Senescence and Innate Immune System. GO annotations related to this gene include poly(A) RNA binding and nucleotide binding. An important paralog of this gene is TNRC6A.
UniProtKB/Swiss-Prot for TNRC6B Gene
Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.