TNR Gene
protein-coding GIFtS: 63
GCID: GC01M175291
|
|
tenascin R
| |
Aliases
for TNR gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 4
| Aliases |
|---|
| Tenascin R1 2 | | Tenascin R (Restrictin, Janusin)2 | | TN-R2 3 | | Tenascin-R1 | | Janusin3 | | Janusin3 | | Restrictin3 | | Restrictin3 |
| External Ids: | HGNC: 119531 | Entrez Gene: 71432 | Ensembl: ENSG000001161477 | OMIM: 6019955 | UniProtKB: Q927523 |
|---|
|
Export aliases for TNR gene to outside databasesPrevious GC identifers: GC01M172816 GC01M170720 GC01M171872 GC01M172531 GC01M172023 GC01M173558 GC01M146518
Summaries
for TNR gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TNR:
Tenascin-R (TNR) is an extracellular matix protein expressed primarily in the central nervous system. It is a member ofthe tenascin (TN) gene family, which includes at least 3 genes in mammals: TNC (or hexabrachion; MIM 187380), TNX(TNXB; MIM 600985), and TNR (Erickson, 1993 (PubMed 7694605)). The genes are expressed in distinct tissues atdifferent times during embryonic development and are present in adult tissues.(supplied by OMIM, Mar 2008)
UniProtKB/Swiss-Prot: TENR_HUMAN, Q92752Function: Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrixcomponents. These interactions can influence cellular behavior by either evoking a stable adhesion anddifferentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibitsRGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and celldetachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation.Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B mayplay a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linkedchondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediate inhibition of celladhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate theadhesive properties of TNR over the course of development and during synapse maintenance (By similarity)
Gene Wiki entry for TNR (Tenascin-R)
fRNAdb sequence ontology for TNR:
ncRNA - An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.
View fRNAdb secondary structures for TNR |
Genomic Views
for TNR gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TNR gene promoter:
LHX3b/Lhx3b Sox5 STAT1 RP58 ATF-2 Olf-1 HEN1 CRE-BP1 LHX3a/Lhx3a PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for TNR
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TNR |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q24 Ensembl cytogenetic band: 1q25.1 HGNC cytogenetic band: 1q24TNR Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M175291: view genomic region
(about GC identifiers)
Start:
|
175,291,935 bp from pter |
End:
|
175,712,906 bp from pter |
Size:
|
420,972 bases |
Orientation:
|
minus strand |
ORGUL member locations:
Legend (see complete legend)
 |
Proteins
for TNR gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TENR_HUMAN, Q92752 (See
protein sequence)Recommended Name: Tenascin-R precursor Size: 1358 amino acids; 149562 Da
Subunit: Forms oligomers. Interacts with CNTN1, TNC, and FN1. Interacts with BCAN and ACAN in a calcium-dependentmanner. Interacts with SCN2B, PTPRZ1, and CSPG3 (By similarity)
Subcellular location: Secreted, extracellular space, extracellular matrix
Secondary accessions: C9J563 Q15568 Q5R3G0Alternative splicing: 2 isoforms: Q92752-1 Q92752-2 Explore the universe of human proteins at neXtProt for TNR: NX_Q92752
Post-translational modifications:
Contains N-linked oligosaccharides, O-linked sialylated structures and O-linked chondroitin sulfate glycosaminoglycans.Contains N-linked oligosaccharides with a sulfated carbohydrate structure (By similarity). O-glycosylated on Thr-36 orThr-37 with a core 1 or possibly core 8 glycan1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q92752
TNR Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003276.3
ENSEMBL proteins: ENSP00000356646 ENSP00000403413 ENSP00000263525
Human Recombinant Protein Products for TNR:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
TNR for ontologies About GeneDecksing
TNR Antibody Products:
Assay Products for TNR: |
Protein
Domains /
Families
for TNR gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TNR for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q92752ProtoNet protein and cluster: Q92752 1 Blocks protein family: IPB002181 Fibrinogen
UniProtKB/Swiss-Prot: TENR_HUMAN, Q92752Domain: The EGF-like domains mediate interaction with CNTN1. The fibronectin type-III domains 3-5 mediate interactionwith BCAN. The fibronectin type-III domains 1-2 and 7-9 mediate interaction with SCN2B (By similarity)Similarity: Belongs to the tenascin familySimilarity: Contains 5 EGF-like domainsSimilarity: Contains 1 fibrinogen C-terminal domainSimilarity: Contains 9 fibronectin type-III domains |
Function
for TNR gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: TENR_HUMAN, Q92752Function: Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrixcomponents. These interactions can influence cellular behavior by either evoking a stable adhesion anddifferentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibitsRGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and celldetachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation.Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B mayplay a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linkedchondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediate inhibition of celladhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate theadhesive properties of TNR over the course of development and during synapse maintenance (By similarity) Genatlas biochemistry entry for TNR:tenascin-R,extracellular neural recognition molecule,expressed in glia and some neuronal subtypes,including horizontalcells in retina,putative ortholog of mouse loop-tail,interacting with fibronectin-dependent cell attachment andinteraction,inhibitor of CD3-mediated T cell interaction
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
TNR for ontologies About GeneDecksing
Phenotypes:
2 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Tnr):
TNR for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Tnrtm1Msch for TNR
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TNR (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TNR
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TNR (NM_005958) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TNR | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TNR |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNR |
|
Pathways & Interactions
for TNR gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell adhesion_Cell-matrix glycoconjugates | | | 2 | Focal Adhesion | | | 3 | ECM-receptor interaction | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for TNR
1  GeneGo (Thomson Reuters) Pathway for TNR
1  BioSystems Pathway for TNR
2 
Kegg Pathways (Kegg details for TNR):
TNR for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TNR
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/39 Interacting proteins for TNR (Q927523 ENSP000002635254) via UniProtKB, MINT, STRING, and/or I2D (see all 39)About this table
Gene Ontology (GO): 5/20 biological process terms (GO ID links to tree view) (see all 20): About this table
TNR for ontologies About GeneDecksing
|
Drugs & Compounds
for TNR gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
TNR for compounds About GeneDecksing
 Browse Tocris compounds for TNR
2 HMDB Compounds for TNR About this table
6 Novoseek chemical compound relationships for TNR gene About this table
Search CenterWatch for drugs/clinical trials and news about TNR / TENR
|
Transcripts
for TNR gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
| 1 fRNAdb Secondary structure:
REFSEQ mRNAs for TNR gene: NM_003285.2 Unigene Cluster for TNR: Tenascin R Hs.659864 [show with all ESTs]Unigene Representative Sequence: NM_0032853 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000367674(uc009wwu.1 uc010pmz.1) ENST00000422274 ENST00000263525(uc001gkp.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TNR (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TNR
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TNR (NM_005958) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TNR | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TNR |
Additional cDNA sequence: AK295823.1 BC129830.1 X98085.1 Y13359.1 Z67996.1 2 DOTS entries: DT.406347 DT.91720346 24/67 AceView cDNA sequences (see all 67): AI879057 AW160530 BF514861 BF740231 BF055935 BG007389 BF934451 BE223030 CD244497 AW293883 BF929429 AA931902 AA907103 H41327 BP349158 BG912903 CB154570 BE222657 AI298431 BX115029 BX950893 BX645837 BF924442 AV721679
GeneLoc Exon Structure
|
Expression
for TNR gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TNR expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCCAGGTTCT
About this image
See TNR Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TNR
SOURCE GeneReport for Unigene cluster: Hs.659864
UniProtKB/Swiss-Prot: TENR_HUMAN, Q92752Tissue specificity: Brain specific
SABiosciences Expression via Pathway-Focused PCR Array including TNR:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TNR
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TNR | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TNR | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TNR | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNR |
Orthologs
for TNR gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TNR gene from 4/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
TNR1 |
tenascin R (restrictin, janusin) |
75.67(n)
75.52(a) |
|
396213 NM_205276.2 NP_990607.2 |
lizard
(Anolis carolinensis) |
Reptilia |
TNR6 |
-- |
77(a) |
1 ↔ 1 |
4(71897527-72045815) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
BX724236.12 |
-- |
77.3(n) |
|
BX724236.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
AY286489.12 |
-- |
73.82(n) |
|
369191 AY286489.1 |
ENSEMBL Gene Tree for TNR (if available)
TreeFam Gene Tree for TNR (if available) |
Paralogs
for TNR gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TNR gene
- FIBCD12 FCN32 FCN12 FCN22 TNXB2 TNN2 MFAP42 FN12
- TNC2 ANGPTL52
12 SIMAP similar genes for TNR using alignment to 3 protein entries: TENR_HUMAN (see all proteins):FCN3 ANGPTL2 FCN2 MFAP4 FIBCD1 FCN1
ANGPTL7 TNN FGL1 LFIRE1 TNC TNXB
TNR for paralogs About GeneDecksing
|
Genomic Variants
for TNR gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TNR (175291935 - 175541935 bp, first 250kb of TNR)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for TNR
4 CNVs: 34421 6798 74779 4263
6 Indels: 84664 84665 65287 74780 74778 84663
Human Gene Mutation Database (HGMD): TNR
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TNR |
|
Disorders
/ Diseases
for TNR gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TNR for disorders About GeneDecksing
OMIM gene information: 601995OMIM information: 115665 116600 121800 155600 211420 600975 605225 605606 606788 606852 606928 607317 607671 608446 608543 608553 608995
16  diseases for TNR: About MalaCardsehlers-danlos syndrome osteochondritis dissecans pilocytic astrocytoma borna disease
multiple sclerosis astrocytoma medulloblastoma hepatocellular carcinoma
nephropathy breast cancer atherosclerosis cerebritis
neuroblastoma schizophrenia carcinoma neuronitis
1 disease from the University of Copenhagen DISEASES database for TNR:Ehlers-Danlos syndrome 2 Novoseek disease relationships for TNR gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
0 |
1 |
15615725 (1) |
| multiple sclerosis |
0 |
3 |
10417662 (2) |
Human Genome Epidemiology (HuGE) Navigator: TNR (17 documents)
Export disorders for TNR gene to outside databases
|
Publications
for TNR gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TNR gene, integrated from 9 sources (see all 100):
(articles sorted by number of sources associating them with TNR) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human tenascin-R: complete primary structure, pre-mRNA alternative splicing and gene localization on chromosome 1q23-q24. (PubMed id 8626505)1, 2, 3, 9 Carnemolla B.... Zardi L. (1996)
- The human tenascin-R gene. (PubMed id 8940128)1, 3, 9 Leprini A....Zardi L. (1996)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Dissection of complex molecular interactions of neurofascin with axonin-1, F11, and tenascin-R, which promote attachment and neurite formation of tectal cells. (PubMed id 9722619)1, 9 Volkmer H....Rathjen F.G. (1998)
- Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and 'brain-type' neutral N-glycans. (PubMed id 10406848)1, 9 Zamze S....Wing D.R. (1999)
- Parallel genotyping of 10,204 single nucleotide polym orphisms to screen for susceptible genes for IgA nephropathy. (PubMed id 19890582)1, 9 Woo K.T....Chan C.M. (2009)
- Hippocampal metaplasticity induced by deficiency in the extracellular matrix glycoprotein tenascin-R. (PubMed id 17537973)1, 9 Bukalo O....Dityatev A. (2007)
- High affinity binding and overlapping localization of neurocan and phosphacan/protein-tyrosine phosphatase-zeta/beta with tenascin-R, amphoterin, and the heparin-binding growth-associated molecule. (PubMed id 9507007)1, 9 Milev P....Margolis R.U. (1998)
- Assignment of the tenascin-R gene (Tnr) to mouse chromosome 4 band E2 by fluorescence in situ hybridization; refinement of the human TNR location to chromosome 1q24. (PubMed id 9371410)1, 9 Arrigo G....Zardi L. (1997)
- Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study. (PubMed id 18521090)1, 9 Lavedan C....Polymeropoulos M.H. (2008)
|
External Searches for TNR gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TNR gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TNR gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TNR gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for TNR gene:
Search GeneIP for patents involving TNR
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TNR gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TNR | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TNR | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TNR | | | OriGene Protein Over-expression Lysate for TNR | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TNR | | OriGene 3'-UTR Clone for TNR | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TNR | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TNR | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TNR | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TNR | | OriGene Custom Protein Services for TNR | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TNR | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TNR | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TNR | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TNR | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TNR | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TNR |
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| | | | Search Tocris compounds for TNR |
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 | | | TNR Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNR |
|  |  |  |  | | | | Search ThermoFisher Antibodies for TNR |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TNR |
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GeneCards Homepage -
Last full update: 18 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013 , 14 May 2013
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