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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TNP1 Gene

protein-coding GIFtS: 57
GCID: GC02M217724

transition protein 1 (during histone to protamine replacement)

Explore 4 diseases affiliated with
TNP1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Transition Protein 1 (During Histone To Protamine Replacement)¹ ²
STP-1² ³
TP-1² ³
TP1²
Spermatid Nuclear Transition Protein 1²

External Ids:	HGNC: 11951¹	Entrez Gene: 7141²	Ensembl: ENSG00000118245⁷	OMIM: 190231⁵	UniProtKB: P09430³

Export aliases for TNP1 gene to outside databases

Previous GC identifers: GC02M215821 GC02M216445 GC02M217688 GC02M217926 GC02M217549 GC02M217432 GC02M209578

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TNP1:

Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself

replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 (PubMed

2249851)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: STP1_HUMAN, P09430

Function: In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact,

non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal

transition proteins

Gene Wiki entry for TNP1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_005403.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TNP1 gene promoter:
SRF SRF (504 AA) NF-E2 p45 LCR-F1 C/EBPalpha YY1 Evi-1 AREB6 HSF2 NF-E2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TNP1 promoter sequence

Search SABiosciences Chromatin IP Primers for TNP1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TNP1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q35-q36 Ensembl cytogenetic band: 2q35 HGNC cytogenetic band: 2q35-q36

TNP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TNP1 gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02M217724: view genomic region (about GC identifiers)

Start:	217,724,181 bp from pter	End:	217,724,787 bp from pter
Size:	607 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: STP1_HUMAN, P09430 (See protein sequence)

Recommended Name: Spermatid nuclear transition protein 1

Size: 55 amino acids; 6424 Da

Subcellular location: Nucleus. Chromosome

Explore the universe of human proteins at neXtProt for TNP1: NX_P09430

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P09430

TNP1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_003275.1

ENSEMBL proteins:

ENSP00000236979

Human Recombinant Protein Products for TNP1:

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	Uscn Proteins for TNP1

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000786	nucleosome	IDA	12743712
GO:0001673	male germ cell nucleus	IEA	--

TNP1 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TNP1 for domains About GeneDecksing

2 InterPro domains/families:

IPR001319 Nuclear_transition_prot1

IPR020062 Nuclear_transition_prot1_CS

Graphical View of Domain Structure for InterPro Entry P09430

ProtoNet protein and cluster: P09430

1 Blocks protein family: IPB001319 Nuclear transition protein 1

UniProtKB/Swiss-Prot: STP1_HUMAN, P09430

Similarity: Belongs to the nuclear transition protein 1 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: STP1_HUMAN, P09430

Function: In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact,

non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal

transition proteins

Genatlas biochemistry entry for TNP1:

transition protein 1 (in haploid spermatogenic cells during transition histone-protamine)

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IMP	12743712

TNP1 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for TNP1:

Cell cycle / mitosis defect

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Tnp1):

reproductive system

TNP1 for phenotypes About GeneDecksing

Animal Models:
Mouse knock-out Tnp1^tm1Mlm for TNP1

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TNP1

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		hsa-miR-34c-5p hsa-miR-181c hsa-miR-449b hsa-miR-181a hsa-miR-181d hsa-miR-449a hsa-miR-34a hsa-miR-143

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In Situ Assay
Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for TNP1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Transcription_CREM signaling in testis

Transcription_CREM signaling in testis

1.00

Transcription CREM signaling in testis

0.96

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for TNP1

Transcription CREM signaling in testis

1 GeneGo (Thomson Reuters) Pathway for TNP1

Transcription CREM signaling in testis

TNP1 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TNP1

STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

5 Interacting proteins for TNP1 (P09430³ ENSP00000236979⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PRKACA	P17612³, ENSP00000309591⁴	I2D: score=1 STRING: ENSP00000309591
CSNK2A1	P68400³, ENSP00000217244⁴	I2D: score=1 STRING: ENSP00000217244
PRKACB	P22694³, ENSP00000359719⁴	I2D: score=1 STRING: ENSP00000359719
PRKACG	P22612³, ENSP00000366488⁴	I2D: score=1 STRING: ENSP00000366488
PRKCA	P17252³, ENSP00000284384⁴	I2D: score=1 STRING: ENSP00000284384

About this table

Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000012	single strand break repair	IDA	12743712
GO:0006337	nucleosome disassembly	IMP	10781074
GO:0006338	chromatin remodeling	IDA	12743712
GO:0006342	chromatin silencing	IEP	11315969
GO:0007275	multicellular organismal development	IEA	--

TNP1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

TNP1 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TNP1
4 Novoseek chemical compound relationships for TNP1 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
protamine	85.3	17	1395729 (1), 10194639 (1), 11315969 (1), 11732576 (1) (see all 10)
paraffin	32.1	2	8605397 (1), 17683460 (1)
gold	0	1	10194639 (1)
serine	0	1	2040274 (1)

Search CenterWatch for drugs/clinical trials and news about TNP1 / STP1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TNP1 gene:

NM_003284.3

Unigene Cluster for TNP1:

Transition protein 1 (during histone to protamine replacement)

Hs.3017 [show with all ESTs]

Unigene Representative Sequence: BM563653

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000236979(uc002vgk.3)

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TNP1
		8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate TNP1 (see all 10):
		hsa-miR-34c-5p hsa-miR-181c hsa-miR-449b hsa-miR-181a hsa-miR-181d hsa-miR-449a hsa-miR-34a hsa-miR-143

		SwitchGear 3'UTR luciferase reporter plasmid: TNP1 3' UTR sequence

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Additional cDNA sequence: BC029516.1

4 DOTS entries:

DT.91690070 DT.120931743 DT.408516 DT.100776396

24/70 AceView cDNA sequences (see all 70):

AL552806 BF059332 BE552039 AL037843 T29843 CR601312 AL037398 BF062064

AL037319 AL038317 BX117749 BF222983 BE503890 AI018791 BC029516 AI990830

NM_003284 BE504726 AW197353 BX438872 AL552771 AI652461 AI670962 BM552864

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for TNP1 About this scheme

ExUns:	1a	·	1b	·	1c	^	2a	·	2b
SP1:
SP2:					-

ECgene alternative splicing isoforms for TNP1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TNP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGAGGAGCA

About this image

TNP1 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Testis

Seminiferous Tubules

Elongated Spermatid

Germ Cells, Male Gametocytes

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See TNP1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TNP1

SOURCE GeneReport for Unigene cluster: Hs.3017

UniProtKB/Swiss-Prot: STP1_HUMAN, P09430

Tissue specificity: Testis

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of human and mouse.

Orthologs for TNP1 gene from 1/5 species (see all 5) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Tnp1^{1 , 5}	transition protein 1^{1, 5}	89.09(n)¹ 87.27(a)¹		1 (36.94 cM)⁵ 21958¹ NM_009407.2¹ NP_033433.1¹ 73015083⁵

ENSEMBL Gene Tree for TNP1 (if available)
TreeFam Gene Tree for TNP1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs115047295^1,2		--	217723683(+)	`TTTACA/CAAGAA`	1	--	int¹		1		WA	118
rs147179861^1,2		--	217723693(+)	`ACATGC/TTGGTC`	1	--	int¹		0	--	--	--	--
rs12694398^1,2	C,F,A	--	217723737(+)	`CTAATC/ACTGCC`	1	--	int¹		12		NA WA CSA EA	374
rs140554190^1,2		--	217723928(+)	`TGAATA/GCATTT`	1	--	int¹		0	--	--	--	--
rs142216500^1,2		--	217723943(+)	`CTTTTA/TTATCT`	1	--	int¹		0	--	--	--	--
rs150807753^1,2		--	217724078(+)	`TTTGAC/TATTTT`	1	--	int¹		0	--	--	--	--
rs139015240^1,2		--	217724209(+)	`AGATGC/TTGGGG`	1	--	ut3¹		0	--	--	--	--
rs189489642^1,2		--	217724212(+)	`TGTTGA/GGGAAA`	1	--	ut3¹		0	--	--	--	--
rs147713572^1,2	C,F	--	217724393(+)	`GCTCAC/TAAGTG`	2	L	syn¹		1		NA	4550
rs201394603^1,2		--	217724404(+)	`GGAGCA/GGTAAT`	2	R C	mis¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TNP1 (217724181 - 217724787 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TNP1: --
Human Gene Mutation Database (HGMD): TNP1

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TNP1

DNA2.0 Custom Variant and Variant Library Synthesis for TNP1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TNP1 for disorders           About GeneDecksing

OMIM gene information: 190231    OMIM disorders: --

4 diseases for TNP1:    About MalaCards

male infertility infertility azoospermia leprosy

2 diseases from the University of Copenhagen DISEASES database for TNP1:

Male infertility Infertility

3 Novoseek disease relationships for TNP1 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
infertility male	61.7	1	16291974 (1)
azoospermia	51.6	6	17683460 (4)
infertility	34.5	2	16989827 (1)

Genetic Association Database (GAD): TNP1
Human Genome Epidemiology (HuGE) Navigator: TNP1 (4 documents)

Export disorders for TNP1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TNP1 gene, integrated from 9 sources (see all 51):
(articles sorted by number of sources associating them with TNP1)

Utopia: connect your pdf to the dynamic
world of online information

Nucleotide sequence of the gene for human transition protein 1 and its chromosomal localization on chromosome 2. (PubMed id 2249851)^{1, 2, 3, 9} Luerssen H....Engel W. (1990)
Single-nucleotide polymorphisms and mutation analyses of the TNP1 and TNP2 genes of fertile and infertile human male populations. (PubMed id 16291974)^{1, 4, 9} Miyagawa Y.... Tanaka H. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The nucleotide sequence of human transition protein 1 cDNA. (PubMed id 3412903)^{1, 2} Luerssen H.... Engel W. (1988)
Quantitative assessment of transition proteins 1, 2 spermatid-specific linker histone H1-like protein transcripts in spermatozoa from normozoospermic and asthenozoospermic men. (PubMed id 17852044)^{1, 9} Jedrzejczak P....Jagodzinski P.P. (2007)
Nuclear transition protein 1 from ram elongating spermatids. Mass spectrometric characterization, primary structure and phosphorylation sites of two variants. (PubMed id 2040274)^{1, 9} Chirat F....Sautiere P. (1991)
Electron microscopic in situ hybridization study of simultaneous expression of TNP1 and PRM1 genes in human spermatids. (PubMed id 11315969)^{1, 9} Siffroi J.P....Dadoune J.P. (1998)
Identification of novel polymorphisms in the nuclear protein genes and their relationship with human sperm protamine deficiency and severe male infertility. (PubMed id 16989827)^{1, 9} Aoki V.W....Carrell D.T. (2006)
Expression of mRNA and protein of nucleoproteins during human spermiogenesis. (PubMed id 9809674)^{1, 9} Steger K....Bergmann M. (1998)
The amino acid sequence and phosphorylation sites of a boar transition protein 1. (PubMed id 8019440)^{1, 9} Akama K....Hayashi H. (1994)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Disorders
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Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 7141	HGNC: 11951	AceView: TNP1	Ensembl:ENSG00000118245	euGenes: HUgn7141
ECgene: TNP1	H-InvDB: TNP1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for TNP1	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for TNP1	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for TNP1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TNP1 gene:
Search GeneIP for patents involving TNP1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013 , 14 May 2013

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TNP1 Gene

transition protein 1 (during histone to protamine replacement)

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TNP1 Gene

transition protein 1 (during histone to protamine replacement)

Aliasesfor TNP1 gene

Summariesfor TNP1 gene

Genomic Viewsfor TNP1 gene

Proteinsfor TNP1 gene

Protein Domains /Familiesfor TNP1 gene

Functionfor TNP1 gene

Pathways & Interactionsfor TNP1 gene

Drugs & Compoundsfor TNP1 gene

Transcriptsfor TNP1 gene

Expression for TNP1 gene

Orthologsfor TNP1 gene

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Genomic Variantsfor TNP1 gene

Disorders / Diseasesfor TNP1 gene

Publicationsfor TNP1 gene

External Searches for TNP1 gene

Genome Databases showing TNP1 gene

Other Databases showing TNP1 gene

Specialized Databases showing TNP1 gene

Intellectual Propertyfor TNP1 gene

Productsfor TNP1 gene

View Random Gene

Aliases
for TNP1 gene

Summaries
for TNP1 gene

Genomic Views
for TNP1 gene

Proteins
for TNP1 gene

Protein Domains /
Families
for TNP1 gene

Function
for TNP1 gene

Pathways & Interactions
for TNP1 gene

Drugs & Compounds
for TNP1 gene

Transcripts
for TNP1 gene

Expression
for TNP1 gene

Orthologs
for TNP1 gene

Paralogs
for TNP1 gene

Genomic Variants
for TNP1 gene

Disorders / Diseases
for TNP1 gene

Publications
for TNP1 gene

Intellectual Property
for TNP1 gene

Products
for TNP1 gene