Aliases for TNP1 Gene
External Ids for TNP1 Gene
Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).[supplied by OMIM, Mar 2008]
GeneCards Summary for TNP1 Gene
TNP1 (Transition Protein 1 (During Histone To Protamine Replacement)) is a Protein Coding gene. Among its related pathways are Transcription_CREM signaling in testis.
UniProtKB/Swiss-Prot for TNP1 Gene
In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins