External Ids for TNNC2 Gene
Previous GeneCards Identifiers for TNNC2 Gene
Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008]
GeneCards Summary for TNNC2 Gene
TNNC2 (Troponin C2, Fast Skeletal Type) is a Protein Coding gene. Among its related pathways are Calcium signaling pathway and Striated Muscle Contraction. GO annotations related to this gene include calcium ion binding and actin binding. An important paralog of this gene is CABP2.
UniProtKB/Swiss-Prot for TNNC2 Gene
Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.