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TNN Gene

protein-coding   GIFtS: 54
GCID: GC01P175036

Tenascin N

  See TNN-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tenascin N1 2
TN-N2 3
TN-W2
tenascin-N2
TNNC25

External Ids:    HGNC: 229421   Entrez Gene: 639232   Ensembl: ENSG000001203327   OMIM: 1910395   UniProtKB: Q9UQP33   

Export aliases for TNN gene to outside databases

Previous GC identifers: GC01P171627 GC01P172286 GC01P172276 GC01P171768 GC01P173303 GC01P146264


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TNN Gene:
TNN (tenascin N) is a protein-coding gene. Diseases associated with TNN include dysplastic nevus syndrome. GO annotations related to this gene include integrin binding and identical protein binding. An important paralog of this gene is TNR.

UniProtKB/Swiss-Prot: TENN_HUMAN, Q9UQP3
Function: Involved in neurite outgrowth and cell migration in hippocampal explants (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_004487.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the TNN gene promoter:
         CREB   RP58   AML1a   Pbx1a   FOXJ2 (long isoform)   deltaCREB   FOXJ2   E4BP4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTNN promoter sequence
   Search Chromatin IP Primers for TNN

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TNN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23-q24   Ensembl cytogenetic band:  1q25.1   HGNC cytogenetic band: 1q23-q24

TNN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TNN gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P175036:  view genomic region     (about GC identifiers)

Start:
175,036,994 bp from pter      End:
175,117,202 bp from pter
Size:
80,209 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TENN_HUMAN, Q9UQP3 (See protein sequence)
Recommended Name: Tenascin-N precursor  
Size: 1299 amino acids; 144034 Da
Secondary accessions: B9EGP3 Q5R360

Explore the universe of human proteins at neXtProt for TNN: NX_Q9UQP3

Explore proteomics data for TNN at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn1149
  • Modification sites at PhosphoSitePlus

  • See TNN Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_071376.1  
    ENSEMBL proteins: 
     ENSP00000239462  
    Reactome Protein details: Q9UQP3

    TNN Human Recombinant Protein Products:

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    Cloud-Clone Corp. CLIAs for TNN
    Search eBioscience for ELISAs for TNN 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    FN3: Fibronectin type III domain containing
    FIBC: Fibrinogen C domain containing

    Selected InterPro protein domains (see all 7):
     IPR020837 Fibrinogen_CS
     IPR003961 Fibronectin_type3
     IPR013032 EGF-like_CS
     IPR014715 Fibrinogen_a/b/g_C_2
     IPR002181 Fibrinogen_a/b/g_C_dom

    Graphical View of Domain Structure for InterPro Entry Q9UQP3

    ProtoNet protein and cluster: Q9UQP3

    1 Blocks protein domain: IPB002181 Fibrinogen

    UniProtKB/Swiss-Prot: TENN_HUMAN, Q9UQP3
    Similarity: Belongs to the tenascin family
    Similarity: Contains 3 EGF-like domains
    Similarity: Contains 1 fibrinogen C-terminal domain
    Similarity: Contains 9 fibronectin type-III domains


    Find genes that share domains with TNN           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TENN_HUMAN, Q9UQP3
    Function: Involved in neurite outgrowth and cell migration in hippocampal explants (By similarity)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005178integrin binding IEA--
    GO:0005515protein binding ----
    GO:0042802identical protein binding IEA--
         
    Find genes that share ontologies with TNN           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TNN
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TNN
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    6 qRT-PCR Assays for microRNAs that regulate TNN:
    hsa-miR-140-5p hsa-miR-299-5p hsa-miR-203 hsa-miR-125a-3p hsa-miR-491-3p hsa-miR-338-3p
    SwitchGear 3'UTR luciferase reporter plasmidTNN 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TNN

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TENN_HUMAN, Q9UQP3: Secreted, extracellular space, extracellular matrix
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    cytosol2
    nucleus2
    plasma membrane2
    endoplasmic reticulum1
    golgi apparatus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005578proteinaceous extracellular matrix IEA--
    GO:0009986cell surface IEA--

    Find genes that share ontologies with TNN           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TNN About    
    See pathways by source

    SuperPathContained pathways About
    1Focal adhesion
    Focal adhesion0.65
    ECM-receptor interaction0.31
    Focal Adhesion0.65
    2Degradation of the extracellular matrix
    Extracellular matrix organization0.34
    3PI3K-Akt signaling pathway
    PI3K-Akt signaling pathway
    4MicroRNAs in cancer
    MicroRNAs in cancer
    5ECM proteoglycans
    ECM proteoglycans


    Find genes that share SuperPaths with TNN           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for TNN
        Focal Adhesion

    1 Reactome Pathway for TNN
        ECM proteoglycans


    4 Kegg Pathways  (Kegg details for TNN):
        PI3K-Akt signaling pathway
    Focal adhesion
    ECM-receptor interaction
    MicroRNAs in cancer

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TNN
    Interactions:

        Search GeneGlobe Interaction Network for TNN

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TNN (Q9UQP33 ENSP000002394624) via UniProtKB, MINT, STRING, and/or I2D (see all 25)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACTN2P356093, ENSP000003555374I2D: score=1 STRING: ENSP00000355537
    ITGA1ENSP000002825884STRING: ENSP00000282588
    ITGA10ENSP000003583104STRING: ENSP00000358310
    ITGA11ENSP000003272904STRING: ENSP00000327290
    ITGA2ENSP000002965854STRING: ENSP00000296585
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007160cell-matrix adhesion IEA--
    GO:0007409axonogenesis IEA--
    GO:0016049cell growth ISS--
    GO:0016477cell migration ISS--

    Find genes that share ontologies with TNN           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TNN (TENN)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TNN gene: 
    NM_022093.1  

    Unigene Cluster for TNN:

    Tenascin N
    Hs.156369  [show with all ESTs]
    Unigene Representative Sequence: AK127044
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000239462(uc010pmx.1 uc001gkl.1)
    miRNA
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    6 qRT-PCR Assays for microRNAs that regulate TNN:
    hsa-miR-140-5p hsa-miR-299-5p hsa-miR-203 hsa-miR-125a-3p hsa-miR-491-3p hsa-miR-338-3p
    SwitchGear 3'UTR luciferase reporter plasmidTNN 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TNN
    Predesigned siRNA for gene silencing in human, mouse, rat TNN
    Clone
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    OriGene ORF clones in mouse, rat for TNN
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TNN (NM_001903)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TNN
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TNN
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TNN
      QuantiTect SYBR Green Assays in human, mouse, rat TNN
      QuantiFast Probe-based Assays in human, mouse, rat TNN

    Additional mRNA sequence: 

    AK127044.1 AK127654.1 AL049689.1 BC136619.1 BC144305.1 

    1 DOTS entry:

    DT.40267896 

    13 AceView cDNA sequences:

    AL049689 BM723148 BM677670 AI378673 BF432086 AK127044 AA558949 AK127654 
    BX095893 BM712922 AI803573 CF780884 AI338459 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TNN expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCACCAGGC
    TNN Expression
    About this image

    TNN Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TNN Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.156369
        Custom PCR Arrays for TNN
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNN

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TNN gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tnn1 , 5 tenascin N1, 5 78.85(n)1
    75.31(a)1
      1 (69.40 cM)5
    3292781  NM_177839.31  NP_808507.21 
     1600850365 
    chicken
    (Gallus gallus)
    Aves TNN1 tenascin N 64.25(n)
    57.54(a)
      424435  XM_001233252.2  XP_001233253.2 
    lizard
    (Anolis carolinensis)
    Reptilia TNN6
    tenascin N
    57(a)
    1 ↔ 1
    4(71753438-71821158)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tnn1 tenascin N 53.04(n)
    46.35(a)
      100491528  XM_002931467.2  XP_002931513.2 
    zebrafish
    (Danio rerio)
    Actinopterygii tenw2 tenascin W 73.32(n)   30234  AJ001423.1 


    ENSEMBL Gene Tree for TNN (if available)
    TreeFam Gene Tree for TNN (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TNN gene
    TNR2  FGA2  ANGPTL42  ANGPTL32  TNXB2  TNC2  FN12  ANGPTL52  
    8 SIMAP similar genes for TNN using alignment to 1 protein entry:     TENN_HUMAN:
    FCN2    FCN3    ANGPTL7    MFAP4    FCN1    FGL1
    TNC variant protein    TNR

    Find genes that share paralogs with TNN           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TNN (see all 2066)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1894705521,2
    C--175035031(+) ACTATG/TAAGAG 1 -- us2k10--------
    rs1820639451,2
    --175035073(+) TTAACA/GCTTGG 1 -- us2k10--------
    rs784412731,2
    F--175035194(+) GAGCAC/TGCACT 1 -- us2k11Minor allele frequency- T:0.02WA 118
    rs751194951,2
    F--175035401(+) CTAACT/CAATAC 1 -- us2k11Minor allele frequency- C:0.08WA 118
    rs1435684541,2
    --175035438(+) AAGGTA/GGCTTC 1 -- us2k10--------
    rs125619711,2
    C,H--175035520(+) TGAAGA/CCCACT 1 -- us2k15Minor allele frequency- C:0.00NS EA NA 406
    rs1480507891,2
    --175035548(+) TGAAAA/GGAAAT 1 -- us2k10--------
    rs121206101,2
    C,F,A--175035627(+) AAGAAG/ACAGAG 1 -- us2k15Minor allele frequency- A:0.06NA CSA 128
    rs66924441,2
    C,F,H--175035637(+) GAAAAA/TAGTCC 1 -- us2k114Minor allele frequency- T:0.01NS EA NA WA CSA 556
    rs1871428121,2
    --175035712(+) GTCACA/CTCTGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TNN (175036994 - 175117202 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for TNN (see all 15):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2719607CNV Deletion23290073
    esv2719596CNV Deletion23290073
    esv2159196CNV Deletion18987734
    esv2719618CNV Deletion23290073
    dgv81e199CNV Deletion23128226
    nsv821166CNV Deletion20802225
    esv2566793CNV Deletion19546169
    nsv3620CNV Insertion18451855
    nsv498693CNV Loss21111241
    nsv508648CNV Loss20534489

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 191039    OMIM disorders: --

    1 disease for TNN:    
    About MalaCards
    dysplastic nevus syndrome

    1 disease from the University of Copenhagen DISEASES database for TNN:
    Dysplastic nevus syndrome

    Find genes that share disorders with TNN           About GenesLikeMe

    Genetic Association Database (GAD): TNN
    Human Genome Epidemiology (HuGE) Navigator: TNN (2 documents)

    Export disorders for TNN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TNN gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with TNN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    2. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (J. Proteome Res. 2005)
    3. Tenascin-N: characterization of a novel member of the tenascin family that mediates neurite repulsion from hippocampal explants. (PubMed id 12812753)1, 9 Neidhardt J....Schachner M. (Mol. Cell. Neurosci. 2003)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    5. A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence. (PubMed id 21703634)4 Wang K.S....Zeng M. (J Psychiatr Res 2011)
    6. Tenascin-W, a new marker of cancer stroma, is elevated in sera of colon and breast cancer patients. (PubMed id 18306355)1 Degen M....Seelentag W. (Int. J. Cancer 2008)
    7. Tenascin-W is a novel marker for activated tumor stroma in low-grade human breast cancer and influences cell behavior. (PubMed id 17909022)1 Degen M....Chiquet-Ehrismann R. (Cancer Res. 2007)
    8. Tenascin-W is found in malignant mammary tumors, promotes alpha8 integrin-dependent motility and requires p38MAPK activity for BMP-2 and TNF-alpha induced expression in vitro. (PubMed id 15592496)1 Scherberich A....Chiquet-Ehrismann R. (Oncogene 2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 63923 HGNC: 22942 AceView: TNN Ensembl:ENSG00000120332 euGenes: HUgn63923
    ECgene: TNN Kegg: 63923 H-InvDB: TNN

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TNN Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TNN Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TNN gene:
    Search GeneIP for patents involving TNN

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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