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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TNK1 Gene

protein-coding   GIFtS: 57
GCID: GC17P007284

tyrosine kinase, non-receptor, 1

 Explore 6 diseases affiliated with
TNK1 via our new
 Human Malady Compendium 
Biological research products
for TNK1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Tyrosine Kinase, Non-Receptor, 11 2
CD38 Negative Kinase 12 3
EC 2.7.10.23 8
Non-Receptor Tyrosine-Protein Kinase TNK12
EC 2.7.108

External Ids:    HGNC: 119401   Entrez Gene: 87112   Ensembl: ENSG000001742927   OMIM: 6080765   UniProtKB: Q134703   

Export aliases for TNK1 gene to outside databases

Previous GC identifers: GC17P007682 GC17P008014 GC17P007227 GC17P007484 GC17P007225 GC17P007178


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TNK1:
The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important
regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development.
This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in
signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a
negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous
tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different
isoforms have been found for this gene. (provided by RefSeq, Oct 2011)

UniProtKB/Swiss-Prot: TNK1_HUMAN, Q13470
Function: Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory
role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more
selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in
phospholipid signal transduction




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010718.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TNK1 gene promoter:
         Max1   AML1a   GCNF   Pax-2   AP-4   Pax-2a   NF-kappaB   GCNF-1   NF-kappaB1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTNK1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TNK1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TNK1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.1   Ensembl cytogenetic band:  17p13.1   HGNC cytogenetic band: 17p13.1

TNK1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TNK1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P007284:  view genomic region     (about GC identifiers)

Start:
7,283,853 bp from pter      End:
7,293,093 bp from pter
Size:
9,241 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TNK1_HUMAN, Q13470 (See protein sequence)
Recommended Name: Non-receptor tyrosine-protein kinase TNK1  
Size: 666 amino acids; 72468 Da
Subunit: Interacts with the SH3 domain of PLCG1 via its Pro-rich domain
Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein
Secondary accessions: O95364 Q8IYI4
Alternative splicing: 2 isoforms:  Q13470-1   Q13470-2   (No experimental confirmation available. Contains a phosphoserine at position 411)

Explore the universe of human proteins at neXtProt for TNK1: NX_Q13470

Post-translational modifications:

  • Autophosphorylated on tyrosine residues1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q13470

  • 3 DME Specific Peptides for TNK1 (Q13470)
     PADRPSF  HRDLATRN  WMFGVTLWEMF 

    TNK1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001238831.1  NP_003976.2  

    ENSEMBL proteins: 
     ENSP00000458834   ENSP00000459799   ENSP00000466590   ENSP00000460146   ENSP00000312309  

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    Uscn Proteins for TNK1

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA10873601
    GO:0005829cytosol IEA--
    GO:0016020membrane IDA10873601


    TNK1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TNK1 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR017441 Protein_kinase_ATP_BS
     IPR001245 Ser-Thr/Tyr_kinase_cat_dom
     IPR011009 Kinase-like_dom
     IPR001452 SH3_domain
     IPR000719 Prot_kinase_cat_dom

    Graphical View of Domain Structure for InterPro Entry Q13470

    ProtoNet protein and cluster: Q13470

    1 Blocks protein family: IPB008266 Tyrosine protein kinase

    UniProtKB/Swiss-Prot: TNK1_HUMAN, Q13470
    Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family
    Similarity: Contains 1 protein kinase domain
    Similarity: Contains 1 SH3 domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: TNK1_HUMAN, Q13470
    Function: Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory
    role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more
    selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in
    phospholipid signal transduction
    Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate

         Genatlas biochemistry entry for TNK1:
    intracellular tyrosine kinase,expressed in all cord blood,bone marrow and adult blood populations and in adult
    prostate,testis,ovary,small intestine,colon

    Enzyme Numbers (IUBMB): EC 2.7.10.21 2 EC 2.7.102

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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004713protein tyrosine kinase activity IDA10873601
    GO:0004715non-membrane spanning protein tyrosine kinase activity NAS10873601
    GO:0004871signal transducer activity TAS8632913
    GO:0005515protein binding IPI10873601
    GO:0005524ATP binding IDA10873601


    TNK1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for TNK1:
     Synthetic lethal with gemcitab 

    Animal Models:
         Mouse knock-out Tnk1tm1Sksuf for TNK1
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Tnk1):
     endocrine/exocrine gland  integument  tumorigenesis 

    TNK1 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Focal Adhesion
    Focal Adhesion1.00
    2Tyrosine Kinases / Adaptors
    Tyrosine Kinases / Adaptors1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for TNK1
        Tyrosine Kinases / Adaptors

    1 BioSystems Pathway for TNK1 
        Focal Adhesion



    TNK1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TNK1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for TNK1 (Q134702, 3 ENSP000003123094) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SFNP319472, 3MINT-3975686 I2D: score=2 
    PLCG1P191743, ENSP000002440074I2D: score=3 STRING: ENSP00000244007
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation TAS8632913
    GO:0007165signal transduction TAS8632913
    GO:0030308negative regulation of cell growth IEA--
    GO:0046580negative regulation of Ras protein signal transduction IEA--
    GO:0046777protein autophosphorylation IDA10873601


    TNK1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TNK1

    2 HMDB Compounds for TNK1    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Search CenterWatch for drugs/clinical trials and news about TNK1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TNK1 gene (2 alternative transcripts): 
    NM_001251902.1  NM_003985.4  

    Unigene Cluster for TNK1:

    Tyrosine kinase, non-receptor, 1
    Hs.203420  [show with all ESTs]
    Unigene Representative Sequence: NM_001251902
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000570896(uc002ggi.4 uc002ggj.4 uc010cmf.3) ENST00000576812
    ENST00000575268 ENST00000574794 ENST00000576207 ENST00000577009 ENST00000576136
    ENST00000576716 ENST00000311668

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    Additional cDNA sequence: 

    AK225403.1 AK310684.1 BC035782.1 HQ696959.1 U43408.1 

    5 DOTS entries:

    DT.109741  DT.95364265  DT.120936171  DT.65284902  DT.75101854 

    24/47 AceView cDNA sequences (see all 47):

    AU099255 BM790022 AI625357 AI095668 CR623896 AI912928 AW771324 BI908132 
    AI431638 BX448526 BE646234 BX448527 AI810287 AA480582 CA440241 AA862013 
    BF844063 BX281082 AA026922 BC035782 CK822675 AI139480 AA618592 AI224174 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for TNK1 (see all 10)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b · 6c ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14
    SP1:                                -                                                                                                                     
    SP2:                                -                                                                                                                     
    SP3:                                                                                                  -                                                   
    SP4:                                                                                                                                                      
    SP5:                                                                                                                                                      


    ECgene alternative splicing isoforms for TNK1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TNK1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGAACAGCCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See TNK1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TNK1

    SOURCE GeneReport for Unigene cluster: Hs.203420

    UniProtKB/Swiss-Prot: TNK1_HUMAN, Q13470
    Tissue specificity: Expressed in all umbilical cord blood, bone marrow and adult blood cell sub-populations and in
    several leukemia cell lines. Highly expressed in fetal blood, brain, lung, liver and kidney. Detected at lower levels
    in adult prostate, testis, ovary, small intestine and colon. Not expressed in adult lung, liver, kidney or brain

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNK1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TNK1 gene from 3/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    zebrafish
    (Danio rerio)
    Actinopterygii tnk16
    tyrosine kinase, non-receptor, 1
    35(a)
    1 ↔ 1
    7(27671370-27690652)
    fruit fly
    (Drosophila melanogaster)
    Insecta Ack6
    Ack
    21(a)
    1 → many
    3L(4108186-4114157)
    worm
    (Caenorhabditis elegans)
    Secernentea kin-256
    Probable tyrosine-protein kinase kin-25
    16(a)
    1 → many
    X(17186066-17193219)


    ENSEMBL Gene Tree for TNK1 (if available)
    TreeFam Gene Tree for TNK1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TNK1 gene
    SYK2  JAK22  JAK32  TNK22  TYK22  ERBB42  JAK12  ERBB32  
    PTK22  ERBB22  ZAP702  PTK2B2  EGFR2  
    10 SIMAP similar genes for TNK1 using alignment to 3 protein entries:     TNK1_HUMAN (see all proteins):
    SRC    EPHA2    ERBB4    FGR    TNK2    ABL1
    FES    CDK4    DKFZp686M05208    tec

    TNK1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/235 NCBI SNPs in TNK1 are shown (see all 235    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1509166461,2
    --7282388(+) TTTTTG/TTGTGT 2 -- us2k10--------
    rs124516351,2
    C,H,--7282390(+) tttttG/Ttgtgt 2 -- us2k10--------
    rs1931454921,2
    --7282415(+) GAGACA/GGGGTT 2 -- us2k10--------
    rs1849192601,2
    --7282471(+) CCACCC/TGCCTC 2 -- us2k10--------
    rs2016423721,2
    --7282542(+) TTTCA-/TATGAG
            
    TATAA
    2 -- us2k10--------
    rs1123385741,2
    --7282670(+) TGAATG/ATATCA 2 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1455901151,2
    --7282865(+) TTCATA/GCATAC 2 -- us2k10--------
    rs1459111731,2
    C,--7282994(+) ACAAC-/AATGAGGA 2 -- us2k10--------
    rs1119954011,2
    C,--7283039(+) GTATCG/AGGCCT 2 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1873773081,2
    --7283043(+) CAGGCC/TTATTA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TNK1 (7283853 - 7293093 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TNK1: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TNK1 for disorders           About GeneDecksing

    OMIM gene information: 608076    OMIM disorders: --

    6 diseases for TNK1:    About MalaCards
    hodgkin's lymphoma    alzheimer's disease    pancreatic cancer    pancreatitis
    leukemia    prostatitis

    Human Genome Epidemiology (HuGE) Navigator: TNK1 (6 documents)

    Export disorders for TNK1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TNK1 gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with TNK1)
        Utopia: connect your pdf to the dynamic
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    1. Tnk1: a novel intracellular tyrosine kinase gene isolated from human umbilical cord blood CD34+/Lin-/CD38- stem/progenitor cells. (PubMed id 8632913)1, 2, 3, 9 Hoehn G.T.... Civin C.I. (1996)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Characterization of the tyrosine kinase Tnk1 and its binding with phospholipase C-gamma1. (PubMed id 10873601)1, 2 Felschow D.M.... Hoehn G.T. (2000)
    4. High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells. (PubMed id 21536687)1 Henderson M.C....Azorsa D.O. (2011)
    5. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    6. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    8. Systematic analysis of candidate genes for Alzheimer' s disease in a French, genome-wide association study. (PubMed id 20413850)1 Laumet G....Lambert J.C. (2010)
    9. Intermediate phenotypes identify divergent pathways t o Alzheimer's disease. (PubMed id 20574532)1 Shulman J.M....De Jager P.L. (2010)
    10. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8711 HGNC: 11940 AceView: TNK1 Ensembl:ENSG00000174292 euGenes: HUgn8711
    ECgene: TNK1 H-InvDB: TNK1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TNK1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TNK1 gene:
    Search GeneIP for patents involving TNK1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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