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TNIP3 Gene

protein-coding   GIFtS: 48
GCID: GC04M122052

TNFAIP3 Interacting Protein 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
TNFAIP3 Interacting Protein 31 2     Listeria Induced2
Listeria-Induced Gene Protein2 3     TNFAIP3-Interacting Protein 32
ABIN-32 3     TNFAIP3-Interacting Protein 3 Beta2
LIND2 3     TNIP3 Beta2
A20-Binding Inhibitor Of NF-Kappa-B Activation 32 3     ABIN33
ABIN-3 Beta2     

External Ids:    HGNC: 193151   Entrez Gene: 799312   Ensembl: ENSG000000507307   OMIM: 6080195   UniProtKB: Q96KP63   

Export aliases for TNIP3 gene to outside databases

Previous GC identifers: GC04M122332 GC04M122445 GC04M122511 GC04M122410 GC04M122272 GC04M117779


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TNIP3 Gene:
TNIP3 (TNFAIP3 interacting protein 3) is a protein-coding gene. Diseases associated with TNIP3 include tonsillitis, and rheumatoid arthritis. GO annotations related to this gene include polyubiquitin binding. An important paralog of this gene is TNIP1.

UniProtKB/Swiss-Prot: TNIP3_HUMAN, Q96KP6
Function: Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis
factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression
inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6
and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000004.12  NT_016354.20  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TNIP3 gene promoter:
         C/EBPbeta   AML1a   Nkx6-1   Pbx1a   Nkx2-2   FOXD3   FOXL1   Evi-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTNIP3 promoter sequence
   Search Chromatin IP Primers for TNIP3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TNIP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q27   Ensembl cytogenetic band:  4q27   HGNC cytogenetic band: 4q27

TNIP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TNIP3 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M122052:  view genomic region     (about GC identifiers)

Start:
122,052,563 bp from pter      End:
122,148,621 bp from pter
Size:
96,059 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TNIP3_HUMAN, Q96KP6 (See protein sequence)
Recommended Name: TNFAIP3-interacting protein 3  
Size: 325 amino acids; 38943 Da
Subunit: Interacts with TNFAIP3. Interacts with polyubiquitin
Sequence caution: Sequence=BAB15018.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAB15018.1; Type=Frameshift; Positions=272; Sequence=CAC85929.1; Type=Frameshift; Positions=272;
Secondary accessions: A1A574 A8K2Z4 B4DVF5 B4E023 Q96PQ3 Q9H780
Alternative splicing: 3 isoforms:  Q96KP6-1   Q96KP6-2   Q96KP6-3   

Explore the universe of human proteins at neXtProt for TNIP3: NX_Q96KP6

Explore proteomics data for TNIP3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TNIP3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001122315.2  NP_001231693.1  NP_079149.3  

    ENSEMBL proteins: 
     ENSP00000057513   ENSP00000427106   ENSP00000426613   ENSP00000424284   ENSP00000411817  

    TNIP3 Human Recombinant Protein Products:

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    TNIP3 Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q96KP6


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TNIP3_HUMAN, Q96KP6
    Function: Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis
    factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression
    inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6
    and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding
    Induction: By Listeria infection. Expression is slightly down-regulated by dexamethasone and slightly up-regulated
    by IL-10. Strongly induced mRNA and protein expression by lipopolysaccharide

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0031593polyubiquitin binding IDA18212736
         
    TNIP3 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Tnip3):
     immune system 

    TNIP3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Tnip3tm1Rds for TNIP3

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TNIP3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TNIP3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TNIP3

    miRNA
    Products:
        
    miRTarBase miRNAs that target TNIP3:
    hsa-mir-142-3p (MIRT021541)

    Block miRNA regulation of human, mouse, rat TNIP3 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate TNIP3:
    hsa-miR-186 hsa-miR-3133 hsa-miR-1911*
    SwitchGear 3'UTR luciferase reporter plasmidTNIP3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TNIP3

    Gene Editing
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TNIP3

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNIP3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    extracellular2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TNIP3
    Interactions:

        GeneGlobe Interaction Network for TNIP3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    Selected Interacting proteins for TNIP3 (Q96KP63 ENSP000000575134) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ALDH9A1P491893, ENSP000003468274I2D: score=1 STRING: ENSP00000346827
    GLDCP233783, ENSP000003707374I2D: score=1 STRING: ENSP00000370737
    KIF11P527323, ENSP000002607314I2D: score=1 STRING: ENSP00000260731
    LRRC47Q8N1G43, ENSP000003674984I2D: score=1 STRING: ENSP00000367498
    NDUFS1P283313, ENSP000002331904I2D: score=1 STRING: ENSP00000233190
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002756MyD88-independent toll-like receptor signaling pathway IDA17088249
    GO:0006954inflammatory response IEA--
    GO:0034142toll-like receptor 4 signaling pathway IDA17088249
    GO:0043124negative regulation of I-kappaB kinase/NF-kappaB signaling IDA17088249
    GO:0071222cellular response to lipopolysaccharide IDA17088249

    TNIP3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TNIP3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TNIP3 gene (3 alternative transcripts): 
    NM_001128843.2  NM_001244764.1  NM_024873.5  

    Unigene Cluster for TNIP3:

    TNFAIP3 interacting protein 3
    Hs.208206  [show with all ESTs]
    Unigene Representative Sequence: NM_001244764
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000057513(uc010ing.3) ENST00000507879 ENST00000509841 ENST00000511909
    ENST00000515605 ENST00000515036 ENST00000506753(uc010ini.3) ENST00000454328(uc011cgj.2 uc021xrj.1)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TNIP3 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate TNIP3:
    hsa-miR-186 hsa-miR-3133 hsa-miR-1911*
    SwitchGear 3'UTR luciferase reporter plasmidTNIP3 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TNIP3
    Predesigned siRNA for gene silencing in human, mouse, rat TNIP3
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    Primer
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    OriGene qPCR primer pairs and template standards for TNIP3
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TNIP3
      QuantiTect SYBR Green Assays in human, mouse, rat TNIP3
      QuantiFast Probe-based Assays in human, mouse, rat TNIP3

    Additional mRNA sequence: 

    AF277289.1 AJ320534.1 AK024815.1 AK290409.1 AK301058.1 AK303192.1 BC128408.1 EF585496.1 

    5 DOTS entries:

    DT.40306429  DT.121227880  DT.100703424  DT.121227887  DT.97769159 

    19 AceView cDNA sequences:

    AL046389 CA309419 CD367219 BP335455 AL046388 BP336923 BP335192 NM_024873 
    BM681878 AJ320534 AF277289 AK024815 BM723695 BG189488 AA314767 BG217064 
    BG203349 BF378712 BF378709 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TNIP3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGAAAGAGAA
    TNIP3 Expression
    About this image

    TNIP3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TNIP3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.208206

    UniProtKB/Swiss-Prot: TNIP3_HUMAN, Q96KP6
    Tissue specificity: Highly expressed in lung, lymph node, thymus and fetal liver. Expressed at lower levels in
    bone marrow, brain, kidney, spleen, leukocytes and tonsils. Could be detected in heart, salivary gland, adrenal
    gland, pancreas, ovary and fetal brain. High levels detected in liver, colon, small intestine, muscle, stomach,
    testis, placenta, thyroid, uterus, prostate, skin and PBL

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNIP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TNIP3 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tnip31 , 5 TNFAIP3 interacting protein 31, 5 75.19(n)1
    62.5(a)1
      6 (30.26 cM)5
    4140841  NM_001001495.21  NP_001001495.21 
     655903985 
    chicken
    (Gallus gallus)
    Aves TNIP31 TNFAIP3 interacting protein 3 58.59(n)
    48.75(a)
      771693  XM_001234939.3  XP_001234940.3 
    lizard
    (Anolis carolinensis)
    Reptilia TNIP36
    TNFAIP3 interacting protein 3
    47(a)
    1 ↔ 1
    5(139310694-139362518)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tnip31 TNFAIP3 interacting protein 3 59.47(n)
    47.89(a)
      100487217  XM_002940318.2  XP_002940364.1 


    ENSEMBL Gene Tree for TNIP3 (if available)
    TreeFam Gene Tree for TNIP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TNIP3 gene
    TNIP12  
    2 SIMAP similar genes for TNIP3 using alignment to 3 protein entries:     TNIP3_HUMAN (see all proteins):
    NAF1    TNIP1

    TNIP3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TNIP3 (see all 1933)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1420637611,2
    --122052271(+) TTTGCA/GGTTGC 3 -- ds50010--------
    rs284323671,2
    C--122052333(+) TATATA/GTATAT 3 -- ds50010--------
    rs2020282801,2
    C--122052335(+) ATGTA-/TATATATATA
    TATATATATATG
    TATAT
    3 -- ds50010--------
    rs1151440341,2
    F--122052341(+) TATATA/GTATAT 3 -- ds50011Minor allele frequency- G:0.16WA 118
    rs1809971461,2
    --122052399(+) ATACAC/TATATA 3 -- ds50010--------
    rs349035161,2
    C--122052639(+) ATCCA-/TAGGGA 3 -- ut310--------
    rs110986011,2
    C,F,A,H--122052640(+) ATCCAA/TGGGAA 3 -- ut31 trp36Minor allele frequency- T:0.02NS EA WA NA 290
    rs110986021,2
    C,F,A,H--122052641(+) TCCAAG/AGGAAG 3 -- ut31 trp312Minor allele frequency- A:0.26NS EA WA NA CSA 1281
    rs1131033361,2
    C,F--122052646(+) GGGAAG/AGAAAA 3 -- ut311Minor allele frequency- A:0.50CSA 2
    rs1463223521,2
    C--122052730(+) GCCATC/TATCAT 3 -- ut310--------

    HapMap Linkage Disequilibrium report for TNIP3 (122052563 - 122148621 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for TNIP3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv4492CNV Insertion18451855
    nsv879860CNV Loss21882294
    nsv879859CNV Gain21882294
    nsv879861CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TNIP3
    DNA2.0 Custom Variant and Variant Library Synthesis for TNIP3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608019    OMIM disorders: --

    5 diseases for TNIP3:    
    About MalaCards
    tonsillitis    rheumatoid arthritis    arthritis    thyroiditis
    prostatitis


    TNIP3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TNIP3
    Human Genome Epidemiology (HuGE) Navigator: TNIP3 (4 documents)

    Export disorders for TNIP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TNIP3 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with TNIP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Two novel genes FIND and LIND differentially expressed in deactivated and Listeria-infected human macrophages. (PubMed id 11345586)1, 2, 3 Staege H.... Schaffner A. (Immunogenetics 2001)
    2. LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF- kappaB activation. (PubMed id 17088249)1, 2, 9 Wullaert A.... Beyaert R. (J. Biol. Chem. 2007)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    5. Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins. (PubMed id 18212736)1, 2 Wagner S.... Beyaert R. (Oncogene 2008)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. ABIN-3: a molecular basis for species divergence in interleukin-10- induced anti-inflammatory actions. (PubMed id 17485448)1, 9 Weaver B.K.... Schreiber R.D. (Mol. Cell. Biol. 2007)
    8. Expression of the NF-kappaB inhibitor ABIN-3 in response to TNF and toll-like receptor 4 stimulation is itself regulated by NF-kappaB. (PubMed id 18081698)1, 9 Verstrepen L....Beyaert R. (J. Cell. Mol. Med. 2008)
    9. A pro-inflammatory role for A20 and ABIN family proteins in human fibroblast-like synoviocytes in rheumatoid arthritis. (PubMed id 22093807)1 Igarashi H....Ishihara K. (Immunol. Lett. 2012)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79931 HGNC: 19315 AceView: TNIP3 Ensembl:ENSG00000050730 euGenes: HUgn79931
    ECgene: TNIP3 H-InvDB: TNIP3

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TNIP3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TNIP3 gene:
    Search GeneIP for patents involving TNIP3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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