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TNFSF15 Gene

protein-coding GIFtS: 62

GC09M116591

tumor necrosis factor (ligand) superfamily, member 15
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
MGC129934 ^¹, ²
MGC129935 ^¹, ²
OTTHUMP00000022739 ^²
TL1 ^¹, ², ³, ⁵
TL1A ^¹, ²
VEGI ^¹, ², ³, ⁵
VEGI192A ^¹, ²

Descriptions
TNF ligand-related molecule 1 ^², ³
TNF superfamily ligand TL1A ^²
Vascular endothelial cell growth inhibitor ^², ³
tumor necrosis factor (ligand) superfamily, member 15 ^²
vascular endothelial growth inhibitor-192A ^²

External Ids
HGNC: 11931¹
Entrez Gene: 9966²
UniProtKB: O95150³
Ensembl: ENSG00000181634⁷

Search outside databases for aliases for TNFSF15 gene

Previous GC identifers: GC09M108349 GC09M109283 GC09M111005 GC09M112927 GC09M114632

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for TNFSF15:

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF)

ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in

either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This

cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate

NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial

cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may

function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced

transcript variant has been reported but the sequence of this transcript has not been determined.

[provided by RefSeq]

UniProtKB/Swiss-Prot: TNF15_HUMAN, O95150

Function: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular

endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis

Gene Wiki entry for TNFSF15 (Vascular_endothelial_growth_inhibitor)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the TNFSF15 gene

Entrez Gene cytogenetic band: 9q32 Ensembl cytogenetic band: 9q32 HGNC cytogenetic band: 9q32

TNFSF15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09M116591: (about GC identifiers)

Start:	116,591,421 bp from pter
End:	116,608,233 bp from pter
Size:	16,813 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000009.10 NT_008470.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: TNF15_HUMAN, O95150 (See protein sequence)

Recommended Name: Tumor necrosis factor ligand superfamily member 15

Size: 251 amino acids; 28087 Da

Subunit: Homotrimer

Subcellular location: Membrane; Single-pass type II membrane protein (Probable)

Subcellular location: Tumor necrosis factor ligand superfamily member 15, secreted form: Secreted

PDB structures from and Proteopedia :

2O0O (3D)

2QE3 (3D)

2RE9 (3D)

2RJK (3D)

2RJL (3D)

Secondary accessions: Q3SX69 Q5VJK8 Q5VWH1 Q8NFE9

Alternative splicing: 3 isoforms: O95150-1 O95150-2 O95150-3

REFSEQ proteins: NP_005109.2

ENSEMBL proteins:

ENSP00000363156 ENSP00000363157

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	R&D Systems Recombinant & Natural Proteins for TNFSF15 (TL1A/TNFSF15)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (TL1A)
	Human Recombinant Proteins from Abnova (TNFSF15)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005615	extracellular space	IEA	--
GO:0005886	plasma membrane	IDA	11911831
GO:0005887	integral to plasma membrane	TAS	9872942

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Antibodies for TNFSF15:

	Invitrogen Antibodies for TNFSF15
	Millipore Mono- and Polyclonal Antibodies for the study of TNFSF15
	Sigma-Aldrich Antibodies for TNFSF15
	R&D Systems Antibodies for TNFSF15 (TL1A/TNFSF15)
	Antibodies from Abcam (TL1A), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (TNFSF15)
	Novus Biologicals Antibodies for TNFSF15

Assays for TNFSF15:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry O95150

ProtoNet protein and cluster: O95150

1 Blocks protein family: IPB006052 Tumor Necrosis Factor

UniProtKB/Swiss-Prot: TNF15_HUMAN, O95150

Similarity: Belongs to the tumor necrosis factor family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TNFSF15)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TNFSF15)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005118

Applied Biosystems Silencer® siRNAs for TNFSF15

Sigma-Aldrich siRNA and siRNA Panels for TNFSF15

Sigma-Aldrich shRNA Panels and shRNA for TNFSF15

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for TNFSF15
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_005118
Myc/DDK tagged cDNA clone in CMV expression vector: NM_005118
untagged cDNA clone in CMV expression vector: NM_005118

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_005118

UniProtKB/Swiss-Prot: TNF15_HUMAN, O95150

Function: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular

endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis

Induction: Up-regulated by IL-1-alpha and TNF-alpha

Genatlas biochemistry entry for TNFSF15:

tumor necrosis factor (ligand) superfamily,member 15,expressed in hematopoietic cells

2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Tnfsf15):

hematopoietic system

immune system

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005125	cytokine activity	IEA	--
GO:0005164	tumor necrosis factor receptor binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for TNFSF15 (Your Favorite Gene powered by Ingenuity)

Death Receptor Signaling

GeneDecks TNFSF15 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for TNFSF15

5/7 Interacting proteins for TNFSF15 (ENSP00000363157³) via UniProtKB, MINT, and/or STRING (see all 7 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RTEL1	ENSP00000349265³	STRING (score=.994)
PLEKHG5	ENSP00000366977³	STRING (score=.951)
TNFSF8	ENSP00000223795³	STRING (score=.912)
LITAF	ENSP00000371231³	STRING (score=.891)
TNFSF13	ENSP00000293826³	STRING (score=.832)

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5/6 Gene Ontology (GO) biological process terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001937	negative regulation of endothelial cell proliferation	IDA	12345
GO:0006919	activation of caspase activity	IDA	11911831
GO:0006955	immune response	IEA	--
GO:0007165	signal transduction	NAS	9872942
GO:0007250	activation of NF-kappaB-inducing kinase activity	IDA	11911831

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for TNFSF15

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TNFSF15)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TNFSF15)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005118

Sigma-Aldrich siRNA and siRNA Panels for TNFSF15

Sigma-Aldrich shRNA Panels and shRNA for TNFSF15

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_005118

REFSEQ mRNAs for TNFSF15 gene:

NM_005118.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_005118

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_005118
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_005118
                                 untagged cDNA clone in CMV expression vector: NM_005118

Additional cDNA sequence:

AF520785.1 AK291642.1 AK313721.1 AY434464.1 BC069435.1 BC074940.2 BC074941.2 BC104462.1

BC104463.1

1 DOTS entry:

DT.99997095

6 AceView cDNA sequences:

NM_005118 BC074940 BC069435 BC074941 AF039390 AF520785

highest scoring ESTs for TNFSF15:

AF520785 BC069435 BC074940 BC074941 CN289458 NM_005118 AF039390 AY434464 BC104462 BC104463

Unigene Cluster for TNFSF15:

Tumor necrosis factor (ligand) superfamily, member 15

Hs.241382 [show with all ESTs]

Unigene Representative Sequence: AF520785

GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:

ENST00000374044 ENST00000374045

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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TNFSF15 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for TNFSF15

¹ / ² / ³

2 probe-sets matching TNFSF15 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
221085_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_005118	0.60	1.00	0.82	1
221085_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TATATCAAAA

SOURCE GeneReport for Unigene cluster: Hs.241382
UniProtKB/Swiss-Prot: TNF15_HUMAN, O95150
Tissue specificity: Specifically expressed in endothelial cells. Detected in monocytes, placenta,
lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for TNFSF15 gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	TNFSF15¹	--	tumor necrosis factor (ligand) superfamily, member more	82.87(n) 80.08(a)	481688 XM_862674.1 XP_867767.1
chimpanzee (Pan troglodytes)	TNFSF15¹	--	tumor necrosis factor (ligand) superfamily, member more	99.34(n) 99.2(a)	473468 XM_528839.2 XP_528839.2
cow (Bos taurus)	TNFSF15¹	--	tumor necrosis factor (ligand) superfamily, member more	86.27(n) 83.2(a)	514239 XM_592054.3 XP_592054.2
rat (Rattus norvegicus)	Tnfsf15¹	--	tumor necrosis factor (ligand) superfamily, member more	79.35(n) 70.85(a)	252878 NM_145765.1 NP_665708.1
mouse (Mus musculus)	Tnfsf15^{1, 5}	4⁵	tumor necrosis factor (ligand) superfamily, member more^{1, 5}	78.41(n)¹ 67.61(a)¹	326623¹ NM_177371.2¹ NP_796345.2¹ AF520786⁵ AY764130⁵ (see all 8)

About this table Species with no ortholog for TNFSF15

ENSEMBL Gene Tree for TNFSF15

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
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Paralogs for TNFSF15 gene

FASLG² ENSG00000204496² TNF² TNFSF14²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/106 NCBI SNPs in TNFSF15 are shown (see all 106 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 56)

AB	SNP ID	Valid	Chr 9 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs1407308^1,2	A,C,F,H,O	116610044(+)	`AACTGT/GTATTC`	1	--	ng3¹		11	EU EA WA NA	978
	rs6478109^1,2	A,C,F,H	116608587(+)	`TGCAGG/ATTGGG`	1	--	ng3¹		7	NA EU EA WA	556
	rs12682881^1,2	A,C,F,H	116591274(+)	`TTAACC/TAGGTA`	1	--	ng5¹		4	EU EA WA	416
	rs7848647^1,2	A,C,F,H	116608867(+)	`GAGTAC/TGAGGC`	1	--	ng3¹		7	EU EA WA NA	558
	rs1891836^1,2	C,F,H	116591076(-)	`ATATGG/AGATTA`	1	--	ng5¹		4	EU EA WA	416
	rs16931745^1,2	C,F,H	116592979(+)	`TTTTTA/TAAGTG`	1	F/L	mis¹		11	NA EU EA WA	978
	rs16931739^1,2	C,F,H	116592012(+)	`CTGTGT/CGAACA`	1	--	ut3¹ ese³		11	NA EU EA WA	978
	rs12682886^1,2	C,F,H	116591340(+)	`GCTATC/GTTCCA`	1	--	ng5¹		11	EU EA WA NA	978
	rs12682952^1,2	C,H	116592062(+)	`CAAGGC/TATGAA`	1	--	ut3¹ ese³		4	EU EA WA	420
	rs7862688^1,2	A,H	116609140(+)	`ACAGAC/GGGCAA`	1	--	ng3¹		4	EU EA WA	418

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HapMap Linkage Disequilibrium images for TNFSF15 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 604052

3 Novoseek disease relationships for TNFSF15 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
colitis ulcerative	48.95	3	19262684 (1), 14568967 (1)
inflammation	39.73	14	19262684 (2), 15207783 (2), 18598698 (2), 18287561 (2) (see all 6)
inflammatory bowel diseases	27.86	4	14568967 (2), 15207783 (1)

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Human Gene Mutation Database: TNFSF15
Genetic Association Database: TNFSF15
Human Genome Epidemiology Navigator: TNFSF15 (8 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/46 PubMed articles for TNFSF15 gene (see all 46 ):

Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cells. (PubMed id 9434163)^{2, 3, 4} Tan K.B....Truneh A. (1997)
TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator. (PubMed id 11911831)^{1, 3, 4} Migone T.S.... Wei P. (2002)
X-ray crystal structure of TNF ligand family member TL1A at 2.1A. (PubMed id 17935696)^{3, 4} Jin T....Zhang Y.Z. (2007)
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. (PubMed id 16221758)^{3, 6} Yamazaki K....Nakamura Y. (2005)
A novel secreted splice variant of vascular endothelial cell growth inhibitor. (PubMed id 11923219)^{3, 4} Chew L.J....Li L.Y. (2002)
VEGI, a novel cytokine of the tumor necrosis factor family, is an angiogenesis inhibitor that suppresses the growth of colon carcinomas in vivo. (PubMed id 9872942)^{3, 4} Zhai Y.... Yu G.-L. (1999)
VEGI, a new member of the TNF family activates nuclear factor-kappa B and c-Jun N-terminal kinase and modulates cell growth. (PubMed id 10597252)^{3, 4} Haridas V....Aggarwal B.B. (1999)
IBD-associated TL1A gene (TNFSF15) haplotypes determine increased expression of TL1A protein. (PubMed id 19262684)^{1, 3} Michelsen K.S....Targan S.R. (2009)
Circulating levels of TNF-like cytokine 1A (TL1A) and its decoy receptor 3 (DcR3) in rheumatoid arthritis. (PubMed id 18757243)^{1, 3} Bamias G....Sfikakis P.P. (2008)
TL1A both promotes and protects from renal inflammation and injury. (PubMed id 18287561)^{1, 3} Al-Lamki R.S....Bradley J.R. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 9966	HGNC: 11931	AceView: TNFSF15	Ensembl:ENSG00000181634	euGenes: HUgn9966
ECgene: TNFSF15	H-InvDB: TNFSF15

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for TNFSF15	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for TNFSF15
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for TNFSF15:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for TNFSF15-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for TNFSF15		Antibodies for TNFSF15
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for TNFSF15		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (TNFSF15)
	Antibodies (TNFSF15)
	Chimera RNAi (TNFSF15)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Antibodies (TL1A)

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Antibodies for TNFSF15

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TNFSF15 Gene

protein-coding GIFtS: 62

Aliases &
Descriptions
for TNFSF15

Summaries
for TNFSF15

Genomic Location
for TNFSF15

Proteins
for TNFSF15

Protein Domains/
Families
for TNFSF15

Gene Function
for TNFSF15

Pathways & Interactions
for TNFSF15

Drugs & Compounds
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Transcripts
for TNFSF15

Expression
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Orthologs
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Medical News
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Genome Databases showing TNFSF15

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Licensable Technologies
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Services
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

TNFSF15 Gene

protein-coding GIFtS: 62

Aliases & Descriptionsfor TNFSF15

Summariesfor TNFSF15

Genomic Locationfor TNFSF15

Proteinsfor TNFSF15

Protein Domains/Familiesfor TNFSF15

Gene Functionfor TNFSF15

Pathways & Interactionsfor TNFSF15

Drugs & Compoundsfor TNFSF15

Transcriptsfor TNFSF15

Expression for TNFSF15

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Paralogsfor TNFSF15

SNPs/Variantsfor TNFSF15

Disorders & Mutationsfor TNFSF15

Medical Newsfor TNFSF15

Publicationsfor TNFSF15

Search for TNFSF15

Genome Databases showing TNFSF15

Other Databases showing TNFSF15

Specialized Databases showing TNFSF15

Licensable Technologiesfor TNFSF15

Servicesfor TNFSF15

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for TNFSF15

Summaries
for TNFSF15

Genomic Location
for TNFSF15

Proteins
for TNFSF15

Protein Domains/
Families
for TNFSF15

Gene Function
for TNFSF15

Pathways & Interactions
for TNFSF15

Drugs & Compounds
for TNFSF15

Transcripts
for TNFSF15

Expression
for TNFSF15

Orthologs
for TNFSF15

Paralogs
for TNFSF15

SNPs/Variants
for TNFSF15

Disorders & Mutations
for TNFSF15

Medical News
for TNFSF15

Publications
for TNFSF15

Licensable Technologies
for TNFSF15

Services
for TNFSF15