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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TNFRSF8 Gene

protein-coding   GIFtS: 65
GCID: GC01P012123

tumor necrosis factor receptor superfamily, member 8


(Previous symbols: CD30, D1S166E)
 Explore 106 diseases affiliated with
TNFRSF8 via our new
 Human Malady Compendium 
Biological research products
for TNFRSF8
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Tumor Necrosis Factor Receptor Superfamily, Member 81 2     KI-11
CD301 2 3 5     Ki-12
D1S166E1 2 3 5     Cytokine Receptor CD302
Lymphocyte Activation Antigen CD302 3     Tumor Necrosis Factor Receptor Superfamily Member 82
CD30L Receptor2 3     CD30 Antigen3
Ki-1 Antigen2 3     

External Ids:    HGNC: 119231   Entrez Gene: 9432   Ensembl: ENSG000001209497   OMIM: 1532435   UniProtKB: P289083   

Export aliases for TNFRSF8 gene to outside databases

Previous GC identifers: GC01P012187 GC01P011968 GC01P011732 GC01P011832 GC01P012057 GC01P011277


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TNFRSF8:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated,
but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal
transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also
has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against
autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been
reported. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: TNR8_HUMAN, P28908
Function: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of
activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B

Gene Wiki entry for TNFRSF8 (CD30)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_021937.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TNFRSF8 gene promoter:
         STAT5B   p53   STAT1beta   STAT5A   NF-E2 p45   STAT1alpha   STAT2   STAT3   NF-E2   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TNFRSF8 promoter sequence
   Search SABiosciences Chromatin IP Primers for TNFRSF8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TNFRSF8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36   Ensembl cytogenetic band:  1p36.22   HGNC cytogenetic band: 1p36

TNFRSF8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TNFRSF8 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P012123:  view genomic region     (about GC identifiers)

Start:
12,123,434 bp from pter      End:
12,204,264 bp from pter
Size:
80,831 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TNR8_HUMAN, P28908 (See protein sequence)
Recommended Name: Tumor necrosis factor receptor superfamily member 8 precursor  
Size: 595 amino acids; 63747 Da
Subunit: Interacts with TRAF1, TRAF2, TRAF3 and TRAF5
Subcellular location: Isoform Long: Cell membrane; Single-pass type I membrane protein
Subcellular location: Isoform Short: Cytoplasm
Miscellaneous: Most specific Hodgkin disease associated antigen
1 PDB 3D structure from and Proteopedia for TNFRSF8:
1D01 (3D)    
Secondary accessions: B1AN79 Q6P4D9
Alternative initiation: 2 isoforms:  P28908-1   P28908-2   

Explore the universe of human proteins at neXtProt for TNFRSF8: NX_P28908

Post-translational modifications:

  • Phosphorylated on serine and tyrosine residues1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P28908

  • TNFRSF8 Protein expression data from MOPED and PaxDb:    About this image 
    TNFRSF8 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001234.2  NP_694421.1  

    ENSEMBL proteins: 
     ENSP00000263932   ENSP00000421938   ENSP00000398337   ENSP00000390650  

    Human Recombinant Protein Products for TNFRSF8: 
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    Uscn Proteins for TNFRSF8

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005886plasma membrane IEA--
    GO:0016021integral to membrane IEA--

    TNFRSF8 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for TNFRSF8


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TNFRSF8 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR001368 TNFR/NGFR_Cys_rich_reg
     IPR020416 TNFR_8

    Graphical View of Domain Structure for InterPro Entry P28908

    ProtoNet protein and cluster: P28908

    1 Blocks protein family: IPB001368 TNFR/CD27/30/40/95 cysteine-rich region

    UniProtKB/Swiss-Prot: TNR8_HUMAN, P28908
    Similarity: Contains 6 TNFR-Cys repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TNR8_HUMAN, P28908
    Function: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of
    activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B

         Genatlas biochemistry entry for TNFRSF8:
    tumor necrosis factor receptor superfamily,member 8,cell differentiation antigen CD30 (Ki-1),lymphoid
    activating,identified by monoclonal antibodies HRS-1,Ki-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004888transmembrane signaling receptor activity TAS1310894
    GO:0005031tumor necrosis factor-activated receptor activity RCA19641626
         
    TNFRSF8 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for TNFRSF8:
     Decreased Hepatitis C virus re  Increased HPV18 LCR reporter a 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Tnfrsf8):
     cellular  hematopoietic system  immune system 

    TNFRSF8 for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-out Tnfrsf8tm1Mak for TNFRSF8
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TNFRSF8 

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    hsa-miR-3679-3p hsa-miR-203 hsa-miR-623 hsa-miR-502-5p hsa-miR-211 hsa-miR-3922-3p hsa-miR-2355-5p hsa-miR-149
    SwitchGear 3'UTR luciferase reporter plasmidTNFRSF8 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNFRSF8


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/7 super-pathways (see all 7About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Akt Signaling
    Akt Signaling1.00
    Tec Kinases Signaling0.55
    p38 Signaling0.60
    2Apoptosis and survival_Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway
    Apoptosis and survival Anti-apoptotic TNFs/NF-kB/IAP pathway0.46
    Apoptosis and survival_Anti-apoptotic TNFs/NF-kB/IAP pathway0.46
    3PEDF Induced Signaling
    STAT3 Pathway0.47
    Cytokine-cytokine receptor interaction0.26
    4TRAF Pathway
    TNF Superfamily Pathway0.42
    TNF Superfamily - Human Ligand-Receptor Interactions & their Associated Functions0.08
    5TNF-alpha/NF-kB Signaling Pathway
    TNF-alpha/NF-kB Signaling Pathway1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for TNFRSF8
        Apoptosis and survival Anti-apoptotic TNFs/NF-kB/IAP pathway

    1 R&D Systems Pathway for TNFRSF8
        TNF Superfamily - Human Ligand-Receptor Interactions & their Associated Functions

    5/7 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for TNFRSF8 (see all 7)
        STAT3 Pathway
    Molecular Mechanisms of Cancer
    Antioxidant Action of Vitamin-C
    p38 Signaling
    Akt Signaling

    1 GeneGo (Thomson Reuters) Pathway for TNFRSF8
        Apoptosis and survival Anti-apoptotic TNFs/NF-kB/IAP pathway

    1 BioSystems Pathway for TNFRSF8 
        TNF-alpha/NF-kB Signaling Pathway


    1         Kegg Pathway  (Kegg details for TNFRSF8):
        Cytokine-cytokine receptor interaction


    TNFRSF8 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TNFRSF8

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/9 Interacting proteins for TNFRSF8 (P289083 ENSP000002639324) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRAF5O004633, ENSP000002614644I2D: score=4 STRING: ENSP00000261464
    TDP2O955513, ENSP000003674404I2D: score=3 STRING: ENSP00000367440
    TNFSF8P329713, ENSP000002237954I2D: score=2 STRING: ENSP00000223795
    ALKQ9UM733, ENSP000003737004I2D: score=1 STRING: ENSP00000373700
    TRAF2Q129333, ENSP000002476684I2D: score=4 STRING: ENSP00000247668
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction TAS10192335
    GO:0008285negative regulation of cell proliferation TAS10192335
    GO:0033209tumor necrosis factor-mediated signaling pathway RCA19641626
    GO:0042535positive regulation of tumor necrosis factor biosynthetic process IDA16108830
    GO:0043065positive regulation of apoptotic process IDA16108830

    TNFRSF8 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TNFRSF8 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TNFRSF8
    10/14 Novoseek chemical compound relationships for TNFRSF8 gene (see all 14)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    [alcl] 88.6 33 17965727 (5), 16140928 (3), 12754742 (2), 8055109 (1) (see all 15)
    saporin 55 2 7517259 (1), 8903477 (1)
    paraffin 49.7 7 7745117 (2), 8912826 (1), 11866962 (1), 12475440 (1) (see all 6)
    ricin a 35.2 1 2152774 (1)
    ricin 16.1 1 7591211 (1)
    calcium 1.64 5 7866279 (1), 7527901 (1), 7869589 (1)
    lipid 1.03 5 15034047 (3)
    thymidine 0 1 8535215 (1)
    tuberculin 0 1 8568238 (1)
    threonine 0 1 16879614 (1)

    1 PharmGKB related drug/compound annotation for TNFRSF8 gene    About this table
    Drug/compound PharmGKB Annotation
    brentuximab vedotinDL  
    Search CenterWatch for drugs/clinical trials and news about TNFRSF8 / TNR8 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TNFRSF8 gene (2 alternative transcripts): 
    NM_001243.3  NM_152942.2  

    Unigene Cluster for TNFRSF8:

    Tumor necrosis factor receptor superfamily, member 8
    Hs.1314  [show with all ESTs]
    Unigene Representative Sequence: NM_001243
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263932(uc001atq.3 uc010obc.2) ENST00000514649 ENST00000413146(uc001atr.3 uc001ats.3)
    ENST00000479933 ENST00000417814

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    hsa-miR-3679-3p hsa-miR-203 hsa-miR-623 hsa-miR-502-5p hsa-miR-211 hsa-miR-3922-3p hsa-miR-2355-5p hsa-miR-149
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    Additional cDNA sequence: 

    BC063482.1 BC073839.1 BC136400.1 BC141804.1 BC171762.1 D86042.1 M83554.1 S75768.1 

    3 DOTS entries:

    DT.310731  DT.91720897  DT.95153621 

    22 AceView cDNA sequences:

    NM_152942 NM_001243 BC073839 BX110183 BC063482 BF591056 AA047161 BE877671 
    AA310772 BV199006 M83554 D86042 BU927609 BI909097 AA147594 AI203419 
    BI908989 AI699969 BP430908 AA928635 BG495230 AA047162 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TNFRSF8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTTCAACAAA
    TNFRSF8 Expression
    About this image

    TNFRSF8 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Line H9 (WA09) (Embryonic Stem Cell)Early Embryo, Inner Cell Mass
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See TNFRSF8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TNFRSF8

    SOURCE GeneReport for Unigene cluster: Hs.1314
        SABiosciences Expression via Pathway-Focused PCR Arrays including TNFRSF8 (see all 8): 
              Cell Surface Markers in human mouse rat
              Th1/Th2 Response in human mouse rat
              TNF Ligands & Receptors in human mouse rat
              Apoptosis 384HT in human mouse rat
              T-Cell Anergy & Immune Tolerance in human mouse rat

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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TNFRSF8
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNFRSF8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for TNFRSF8 gene from 2/6 species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tnfrsf81 , 5 tumor necrosis factor receptor superfamily, member more1, 5 63.8(n)1
    52.76(a)1
      4 (78.17 cM)5
    219411  NM_009401.21  NP_033427.11 
     1452671375 
    chicken
    (Gallus gallus)
    Aves TNFRSF81 tumor necrosis factor receptor superfamily, member more 49.38(n)
    38.11(a)
      395090  NM_204444.1  NP_989775.1 


    ENSEMBL Gene Tree for TNFRSF8 (if available)
    TreeFam Gene Tree for TNFRSF8 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    1666/1667 NCBI SNPs in TNFRSF8 are shown (see all 1667    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs760118091,2
    --12121459(+) GCCATA/GTCACC 1 -- us2k10--------
    rs1167833061,2
    F--12121525(+) TCTTGC/TGTTCC 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1423833471,2
    --12121682(+) AAGGGA/GCATGA 1 -- us2k10--------
    rs777324871,2
    F--12121802(+) CCCTAT/GAGGGC 1 -- us2k11Minor allele frequency- G:0.04WA 118
    rs770541651,2
    C,F--12122144(+) GGCTTG/AAATCA 1 -- us2k11Minor allele frequency- A:0.03EA 120
    rs1175522171,2
    F--12122175(+) CAGCCG/ACCTCC 1 -- us2k11Minor allele frequency- A:0.02EA 120
    rs1477992821,2
    --12122270(+) TCCATC/TTACCA 1 -- us2k10--------
    rs1136626681,2
    C--12122309(+) CTGCTCATC/-  
            
    CATCC
    1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs97020051,2
    A--12122332(+) atccaC/Tctatg 1 -- us2k10--------
    rs617778601,2
    C--12122373(+) TCCATC/TCACCC 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1385440481,2
    --12122416(+) CTCAC-/CCA   
       TCCAT
    CCATC
    1 -- us2k10--------
    rs115697841,2
    C,F,H--12123146(+) TTCTTG/AGGGCA 1 -- us2k16Minor allele frequency- A:0.04NS EA WA 716
    rs617600481,2
    C--12123153(+) GGCAGA/GAGTGG 1 -- us2k10--------
    rs1487600891,2
    --12123157(+) GTGGA-/GGGTGG 1 -- us2k10--------
    rs1157561671,2
    F--12123340(+) GAGGCG/ATCTCC 1 -- us2k11Minor allele frequency- A:0.03NA 120
    rs1435253251,2
    --12123349(+) CCTAGC/TGTGCC 1 -- us2k10--------
    rs1380202261,2
    --12123376(+) CTGCAC/TGTGTT 1 -- us2k10--------
    rs115697851,2
    C,F,H--12123499(+) CGTGCG/TTTGGG 1 -- ut51 ese315Minor allele frequency- T:0.02NS EA NA 1574
    rs1810355751,2
    --12123636(+) GGCCAA/CCTCAC 1 -- ut510--------
    rs2016714411,2
    --12123647(+) GTCCGG/TCCCCG 1 -- ut510--------
    rs1862756771,2
    --12123813(+) ACCCCG/TTTCCC 1 -- int10--------
    rs1915190491,2
    --12123957(+) TTCATG/TCATTC 1 -- int10--------
    rs115697861,2
    C,F--12124025(+) CCTGCG/AGGCCC 1 -- int13Minor allele frequency- A:0.07NS NA EA 418
    rs115697871,2
    C--12124147(+) GGTCCC/GGTTTG 1 -- int12Minor allele frequency- G:0.02NS WA 298
    rs115697881,2
    C--12124202(+) GGGAGA/TGTTGG 1 -- int1 trp32Minor allele frequency- T:0.03NS WA 298
    rs115697901,2
    C--12124214(+) TGTGGG/ATGAGA 1 -- int12Minor allele frequency- A:0.03NS WA 298
    rs111218531,2
    C,F,H--12124259(+) TCCCCA/GATCCG 1 -- int119Minor allele frequency- G:0.33NS NA WA EA 1356
    rs115697911,2
    C--12124328(+) CCTGGA/TAGAAG 1 -- int11Minor allele frequency- T:0.01NS 180
    rs115697921,2
    C--12124505(+) AGGCCC/TTCAGC 1 -- int11Minor allele frequency- T:0.01NS 180
    rs1814929931,2
    --12124524(+) GACCCC/GGGTGG 1 -- int10--------
    rs1858668521,2
    --12124527(+) CCCGGC/TGGACC 1 -- int10--------
    rs1415009471,2
    C--12124544(+) TAGAA-/CCATA 
     GTAGGTG
    CGAGT
    1 -- int10--------
    rs115697931,2
    F--12124545(+) AGAACCATAGTA 
     GGTGC
    /-
    GAGTG
    1 -- int11Minor allele frequency- -:0.06NS 180
    rs115697941,2
    C,F,H--12124601(+) AGCAGG/ACTGTT 1 -- int17Minor allele frequency- A:0.02NS EA WA 668
    rs1906782691,2
    --12124803(+) TTCCAA/GTGGGC 1 -- int10--------
    rs1418237821,2
    --12124835(+) CCCCCC/GAAGAG 1 -- int10--------
    rs1831965041,2
    --12124931(+) CAAGGG/TCTTGG 1 -- int10--------
    rs115697951,2
    C--12125006(+) CTGAAG/ACTCAT 1 -- int11Minor allele frequency- A:0.01NS 176
    rs1399405581,2
    --12125121(+) CTGAAC/TTCTCA 1 -- int10--------
    rs1498514831,2
    --12125168(+) TGAGTC/TTCACT 1 -- int10--------
    rs1475213391,2
    --12125220(+) CTGCAA/CCCTCT 1 -- int10--------
    rs1400675461,2
    --12125224(+) AACCTA/CTGCCT 1 -- int10--------
    rs20025561,2
    C,F,A,H--12125247(+) TGATTC/TTCCTG 1 -- int17Minor allele frequency- T:0.23NA NS EA WA CSA 367
    rs1475813821,2
    --12125357(+) CTGGTC/TTCGAA 1 -- int10--------
    rs20025571,2
    C,F,A--12125409(+) TGCTAG/AGGTTA 1 -- int16Minor allele frequency- A:0.42NS EA NA WA 368
    rs1878887941,2
    --12125439(+) CCAGCC/TTCCCA 1 -- int10--------
    rs120227401,2
    H--12125513(+) AAAGCA/TAAACT 1 -- int14Minor allele frequency- T:0.00NS EA 420
    rs1906901361,2
    --12125576(+) TTCAAA/TGATAT 1 -- int10--------
    rs1829361311,2
    --12125665(+) CATATA/GTATAG 1 -- int10--------
    rs758255411,2
    C,F--12125668(+) ATATAT/CAGTTT 1 -- int11Minor allele frequency- C:0.04WA 118
    rs1172431061,2
    F--12125771(+) CAGATC/ACTCTG 1 -- int11Minor allele frequency- A:0.03EA 120
    rs1150397611,2
    --12125799(+) TATGTG/AATCTT 1 -- int11Minor allele frequency- A:0.01WA 118
    rs750742581,2
    C,F--12125836(+) ATTTAT/CGTCCT 1 -- int11Minor allele frequency- C:0.06WA 118
    rs1420395991,2
    --12125914(+) CAGCCC/GTATAT 1 -- int10--------
    rs1512226401,2
    --12126003(+) AAATGC/GATTCA 1 -- int10--------
    rs1878433481,2
    --12126141(+) TCTCAA/GTGTGA 1 -- int10--------
    rs1404176591,2
    --12126199(+) CTACCA/GGGGAA 1 -- int10--------
    rs1455479971,2
    --12126210(+) GCTGAA/GCATCT 1 -- int10--------
    rs2020587561,2
    --12126362(+) CGTTA-/TTTTAA 1 -- int10--------
    rs2004583881,2
    --12126364(+) TATTT-/ATAAAA 1 -- int10--------
    rs13180081,2
    C,F,A,H--12126365(-) TTTTTA/TAAATA 1 -- int19Minor allele frequency- T:0.36EA NS NA WA 582
    rs1424471951,2
    --12126365(+) ATTTT-/AAAAAA 1 -- int10--------
    rs1929326361,2
    --12126366(+) ATTTTA/TAAAAA 1 -- int10--------
    rs1828655101,2
    --12126386(+) AATTAA/GGGCTT 1 -- int10--------
    rs2012452121,2
    --12126407(+) AGTTT-/AAAAAT 1 -- int10--------
    rs1875106591,2
    --12126562(+) CTTGCA/CATCAT 1 -- int10--------
    rs1923194221,2
    C--12126594(+) TAGTAC/GAGATG 1 -- int10--------
    rs610719131,2
    C--12126650(+) GGAGAC/TCCATC 1 -- int11Minor allele frequency- T:0.50WA 2
    rs1380616321,2
    --12126656(+) CCATCC/TACCTC 1 -- int10--------
    rs75320051,2
    C,F,A--12126657(+) CATCCG/ACCTCG 1 -- int15Minor allele frequency- A:0.22NA WA CSA 9
    rs1457114881,2
    --12126699(+) GCCACC/TGCCCC 1 -- int10--------
    rs1381884531,2
    --12126773(+) GGCGCA/GATCTC 1 -- int10--------
    rs1848621411,2
    --12126777(+) CAATCG/TCAGCT 1 -- int10--------
    rs608378381,2
    C--12126854(+) ATAGGC/TGCCTG 1 -- int13Minor allele frequency- T:0.00NA WA 6
    rs1442596421,2
    --12126880(+) AATTTC/TTGTAT 1 -- int10--------
    rs1482970201,2
    --12126917(+) GTTGGG/TCAGGC 1 -- int10--------
    rs1150883001,2
    --12127049(+) CAAGAC/TGCCAT 1 -- int11Minor allele frequency- T:0.01WA 118
    rs1158202181,2
    --12127132(+) TGCTTC/TGTATC 1 -- int11Minor allele frequency- T:0.01WA 118
    rs1415952431,2
    --12127133(+) GCTTCA/GTATCA 1 -- int10--------
    rs1143083401,2
    F--12127149(+) TTGTCC/TAATTG 1 -- int11Minor allele frequency- T:0.02WA 118
    rs773906841,2
    F--12127262(+) GTTGCG/CGGGCG 1 -- int11Minor allele frequency- C:0.09NA 120
    rs1475308701,2
    --12127266(+) CGGGGC/TGGGGG 1 -- int10--------
    rs1164775481,2
    C,F--12127293(+) GTGAAC/TTCTGT 1 -- int11Minor allele frequency- T:0.03WA 118
    rs1401079391,2
    --12127312(+) AAATTC/GCCCAA 1 -- int10--------
    rs1455180791,2
    --12127317(+) CCCCAA/GCATCA 1 -- int10--------
    rs1471688651,2
    --12127333(+) CTTGCC/TAGTGC 1 -- int10--------
    rs120351751,2
    H--12127338(+) CAGTGC/TTAAGG 1 -- int14Minor allele frequency- T:0.00NS EA 414
    rs1907551851,2
    --12127453(+) AAAGTA/GTCTTA 1 -- int10--------
    rs1394905251,2
    --12127471(+) CCGGGC/TGCTGT 1 -- int10--------
    rs1922220081,2
    --12127514(+) GCCAAG/TACAGG 1 -- int10--------
    rs1845462881,2
    --12127533(+) TTGAGG/TCCAGG 1 -- int10--------
    rs1893754881,2
    --12127619(+) CAGGCA/GCCTGT 1 -- int10--------
    rs1813087901,2
    --12127655(+) GCAGGA/GGAATC 1 -- int10--------
    rs1496915491,2
    --12127703(+) ACTCCC/TGCCTG 1 -- int10--------
    rs121206881,2
    H--12127725(+) gactgT/Cattta 1 -- int14Minor allele frequency- C:0.00NS EA 386
    rs1158897911,2
    F--12127770(+) AAAAGC/TTCTAT 1 -- int11Minor allele frequency- T:0.03WA 118
    rs748467981,2
    F--12127817(+) CTTAGC/TTAGTT 1 -- int11Minor allele frequency- T:0.06WA 118
    rs1424441371,2
    --12127953(+) GGGGC-/GGGGGG 1 -- int10--------
    rs1454806581,2
    --12128240(+) TCATCA/TGAAGG 1 -- int10--------
    rs1483982551,2
    --12128278(+) TGGCCC/TGGGGG 1 -- int10--------
    rs783729631,2
    F--12128279(+) GGCCCG/AGGGGA 1 -- int11Minor allele frequency- A:0.04WA 118
    rs726410531,2
    C,F--12128435(+) GAGGTA/GGNNNN 1 -- int14Minor allele frequency- G:0.12NA WA EA 362
    rs120290161,2
    C,F,H--12128498(+) GACACA/GCAGAA 1 -- int125Minor allele frequency- N:0.00EA NA NS WA 2562
    rs1856237091,2
    --12128683(+) CTCAGC/TCTAGT 1 -- int10--------
    rs1888699241,2
    --12128740(+) CATGCA/CTGCAT 1 -- int10--------
    rs1816285081,2
    --12128996(+) CGATCC/TCGGCT 1 -- int10--------
    rs1861406601,2
    --12129009(+) CTGCAA/GCCTCC 1 -- int10--------
    rs1465088091,2
    --12129158(+) CTCCTA/GACCTC 1 -- int10--------
    rs1923581681,2
    --12129174(+) CCACCC/TGCCTC 1 -- int10--------
    rs1119948771,2
    --12129305(+) GTCTCG/AGCTCA 1 -- int11Minor allele frequency- A:0.00CSA 1
    rs1447307701,2
    --12129424(+) AGAGAC/TGGGAT 1 -- int10--------
    rs1823860261,2
    --12129473(+) TCAGAA/CGAGCC 1 -- int10--------
    rs745455571,2
    C,F--12129481(+) GCCCCA/C/TCCGCC 1 -- int13WA CSA 6
    rs1410135311,2
    --12129484(+) CCCCCA/GCCTCA 1 -- int10--------
    rs1502156311,2
    --12129500(+) CCAAAA/GTGCTG 1 -- int10--------
    rs1387374321,2
    --12129528(+) CACCAC/TGCCTG 1 -- int10--------
    rs1429694081,2
    --12129650(+) TGTCCC/TCCAAC 1 -- int10--------
    rs1471182491,2
    --12129682(+) AGCTCA/GAGGCT 1 -- int10--------
    rs1385153601,2
    --12129722(+) CATTCA/CACAAA 1 -- int10--------
    rs1439944531,2
    --12129774(+) TGCTGC/TGAGTT 1 -- int10--------
    rs1149200961,2
    F--12129775(+) GCTGCG/AAGTTC 1 -- int11Minor allele frequency- A:0.02WA 118
    rs1473113591,2
    --12129903(+) ACGGGC/TGGCTC 1 -- int10--------
    rs764974751,2
    C,F--12129969(+) AGGGAG/AGCAGC 1 -- int11Minor allele frequency- A:0.08NA 120
    rs44910701,2
    C,F,H--12130051(+) GAGGCC/TGGGGT 1 -- int120Minor allele frequency- T:0.36EA NS NA WA 2422
    rs1487675951,2
    --12130154(+) TTTGGC/TAGGGG 1 -- int10--------
    rs2008797611,2
    C--12130202(+) TGCTGG/TGNNNN 1 -- int10--------
    rs352493511,2
    C--12130203(+) GGGGG-/GCTGGG 1 -- int10--------
    rs562271141,2
    C,F--12130216(+) GGGGGG/ATTGGG 1 -- int13Minor allele frequency- A:0.33NA WA 6
    rs1398855381,2
    --12130219(+) GGATT-/GGGGGGAG 1 -- int10--------
    rs1142541411,2
    C,F--12130262(+) TTGCAT/CTGATC 1 -- int11Minor allele frequency- C:0.02WA 118
    rs1861006531,2
    --12130377(+) ATCTCA/GGCTCA 1 -- int10--------
    rs19341501,2
    C,F,A,H--12130517(+) CGTGTT/CAGCCA 1 -- int17Minor allele frequency- C:0.38NA WA CSA 16
    rs1909697991,2
    --12130546(+) ACCTCA/GTGATC 1 -- int10--------
    rs1507387241,2
    --12130561(+) CGCCTA/GTGTAG 1 -- int10--------
    rs1390499491,2
    --12130582(+) TCACTA/GTGTTG 1 -- int10--------
    rs1163463371,2
    F--12130614(+) CAGGGC/GTCAGG 1 -- int11Minor allele frequency- G:0.03WA 118
    rs1826506581,2
    --12130695(+) TTTCAA/GGCTAG 1 -- int10--------
    rs758601991,2
    C,F--12130698(+) CAAGCT/CAGAAT 1 -- int11Minor allele frequency- C:0.03WA 118
    rs1439657551,2
    --12130769(+) CTGTCC/TGTATT 1 -- int10--------
    rs1873083041,2
    --12130811(+) TCATTC/TTGGGA 1 -- int10--------
    rs1465189421,2
    --12131083(+) TCATTC/GGTTCC 1 -- int10--------
    rs1399974471,2
    --12131209(+) TATAGC/TCCTGG 1 -- int10--------
    rs1113514451,2
    --12131292(+) GGAGTG/TTGAGA 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs1920779351,2
    --12131313(+) CAACAC/TGGCGA 1 -- int10--------
    rs1831191851,2
    --12131322(+) GAAACC/TCTGTC 1 -- int10--------
    rs1455837451,2
    --12131450(+) GAGATC/TGCAGC 1 -- int10--------
    rs1886491041,2
    --12131615(+) TCCCTA/GGCCCT 1 -- int10--------
    rs1488712101,2
    --12131642(+) TCCTTC/GCATCC 1 -- int10--------
    rs1139967321,2
    F--12131681(+) GAGCTC/TGATCT 1 -- int11Minor allele frequency- T:0.02WA 118
    rs1433017851,2
    --12131741(+) TCAGCC/TTCCCA 1 -- int10--------
    rs115818501,2
    C,F,H--12131770(+) CACCCA/GCCACC 1 -- int15Minor allele frequency- G:0.30NA WA 10
    rs1415540091,2
    --12131802(+) TTTTAA/GTACAG 1 -- int10--------
    rs120739511,2
    H--12132331(+) TGTGGG/TGCATT 1 -- int14Minor allele frequency- T:0.00NS EA 418
    rs1151938481,2
    F--12132419(+) GAGAGG/AGTGGC 1 -- int11Minor allele frequency- A:0.02WA 118
    rs1470239961,2
    --12132456(+) GCCTGC/TGGGAG 1 -- int10--------
    rs1382916091,2
    --12132457(+) CCTGCA/GGGAGT 1 -- int10--------
    rs1441391971,2
    --12132506(+) GGGAAA/GGAGCC 1 -- int10--------
    rs1502666661,2
    --12132507(+) GGAAGG/TAGCCT 1 -- int10--------
    rs586251641,2
    C,F--12132632(+) CTGGTG/AGNNNN 1 -- int15Minor allele frequency- A:0.12WA CSA NA EA 362
    rs1161632941,2
    F--12132720(+) ACTCCT/CAGAGG 1 -- int11Minor allele frequency- C:0.03WA 118
    rs803047441,2
    C--12132730(+) GCGTCA/GCCCAC 1 -- int10--------
    rs740529891,2
    C,F--12132793(+) GTTCCT/CGCTCT 1 -- int13Minor allele frequency- C:0.05WA CSA 122
    rs567950701,2
    F--12132885(+) AACCCC/TACCTT 1 -- int11Minor allele frequency- T:0.08WA 118
    rs1158211581,2
    C--12132933(+) GATTCA/GGGTGA 1 -- int10--------
    rs740529901,2
    C--12132934(+) ATTCGG/AGTGAG 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1857288241,2
    --12132957(+) GCAGCA/GGCCAG 1 -- int10--------
    rs1894111921,2
    --12133124(+) AGGATC/TTCATG 1 -- int10--------
    rs1493957931,2
    --12133131(+) CATGAG/TCCCAG 1 -- int10--------
    rs1146291421,2
    F--12133157(+) CTGGGC/TAACAA 1 -- int11Minor allele frequency- T:0.07WA 118
    rs1445026911,2
    --12133173(+) TAGCCA/GGGCAT 1 -- int10--------
    rs1914086241,2
    --12133226(+) TGAGAC/GGATCA 1 -- int10--------
    rs1998844341,2
    --12133321(+) CTTAA-/AAACA 
     AACAAAC
    AAACA
    1 -- int10--------
    rs756254461,2
    --12133428(+) AAGTCG/AAATAC 1 -- int12Minor allele frequency- A:0.06CSA WA 120
    rs1391530611,2
    --12133453(+) GCCCCA/GCTTCC 1 -- int10--------
    rs1136225211,2
    --12133474(+) GGTCCA/GCTATA 1 -- int12Minor allele frequency- G:0.06CSA WA 120
    rs1142064421,2
    F--12133605(+) CCTTTC/TGTTTT 1 -- int11Minor allele frequency- T:0.02WA 118
    rs1838980701,2
    --12133718(+) AGATCA/GTGGCT 1 -- int10--------
    rs1424570421,2
    --12133792(+) ATTACA/GGGCGC 1 -- int10--------
    rs1459522451,2
    --12133814(+) CCTGGA/CTAATT 1 -- int10--------
    rs1398060681,2
    --12133827(+) TATGTA/GTTTTT 1 -- int10--------
    rs1117097821,2
    --12133858(+) ATGTTG/AGCCAA 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1507910481,2
    --12133867(+) AAGCTA/GGTCTC 1 -- int10--------
    rs1391558041,2
    --12133944(+) CACCGC/TACCCA 1 -- int10--------
    rs1499203751,2
    --12133945(+) ACCGCA/GCCCAG 1 -- int10--------
    rs66841431,2
    C,F,A,H--12133949(+) CACCCG/AGCCCA 1 -- int112Minor allele frequency- A:0.46NA WA CSA EA 375
    rs1886259031,2
    --12133959(+) ACTGCA/GTTTTT 1 -- int10--------
    rs1133182051,2
    --12133986(+) GTCCCG/ATGGCG 1 -- int12Minor allele frequency- A:0.06CSA WA 119
    rs1495349551,2
    --12133994(+) CGGCT-/GGTTGC 1 -- int10--------
    rs1457629341,2
    --12134133(+) GAGCCA/GGCACG 1 -- int10--------
    rs1814182481,2
    --12134202(+) AATTCA/GGACTC 1 -- int10--------
    rs1478734121,2
    --12134221(+) ATCTT-/GCTAAA
    ACGGACTC
    GCTCT
    1 -- int10--------
    rs1870024421,2
    --12134224(+) TTGCTA/CAAACG 1 -- int10--------
    rs1902014731,2
    C--12134228(+) TAAAAC/TGGACT 1 -- int10--------
    rs1143020591,2
    F--12134255(+) GTCCAC/TCTCCC 1 -- int11Minor allele frequency- T:0.02NA 120
    rs743667621,2
    --12134274(+) TAATGA/GCCCTG 1 -- int12Minor allele frequency- G:0.06CSA WA 120
    rs1823873081,2
    --12134301(+) CCCTAA/GTGCCA 1 -- int10--------
    rs1416944031,2
    --12134308(+) GCCAAA/GGGCAA 1 -- int10--------
    rs1454384241,2
    --12134339(+) TTTCTC/TTCTTT 1 -- int10--------
    rs1167561761,2
    F--12134536(+) TTCGCT/CGTATT 1 -- int11Minor allele frequency- C:0.05WA 118
    rs1873874841,2
    --12134583(+) CCGCCC/TGCCTC 1 -- int10--------
    rs75506901,2
    C,A--12134614(+) ttacaA/Ggcatg 1 -- int10--------
    rs1476759731,2
    --12134622(+) ATGAGC/GCACCA 1 -- int10--------
    rs1909725951,2
    --12134665(+) CAGTTC/TTGAGA 1 -- int10--------
    rs726410551,2
    C,F--12134690(+) GGCCAA/GCGAAG 1 -- int11Minor allele frequency- G:0.13NA 120
    rs726410561,2
    --12134691(+) GCCAAC/TGAAGT 1 -- int10--------
    rs1423299681,2
    --12134758(+) AAGAGA/TAAGTA 1 -- int10--------
    rs1434041301,2
    --12134800(+) TCTAAA/GATGGA 1 -- int10--------
    rs1483671521,2
    --12134813(+) CCTCTC/GGAATG 1 -- int10--------
    rs1450054261,2
    C--12134837(+) ATTTG-/TGTT  
            
    TGTTT
    1 -- int10--------
    rs728619431,2
    C--12134850(+) TGTTTG/ATTTAT 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1154408121,2
    F--12134931(+) ACCTCG/AAATTC 1 -- int11Minor allele frequency- A:0.06WA 118
    rs1809822311,2
    --12134957(+) CCTCCC/TACCTT 1 -- int10--------
    rs67010991,2
    C,F,A--12135150(+) ACAAAG/ACTTAG 1 -- int17Minor allele frequency- A:0.25NA WA CSA EA 131
    rs1856014061,2
    --12135255(+) GAGATC/TGCACC 1 -- int10--------
    rs66902851,2
    C--12135325(+) TTTTAA/TAGAGA 1 -- int12Minor allele frequency- T:0.25NA 4
    rs1903198121,2
    --12135357(+) AGGCTA/GGTCTT 1 -- int10--------
    rs1828947301,2
    --12135376(+) GGGCTC/TAAGCA 1 -- int10--------
    rs1504693851,2
    --12135398(+) TTGGCC/TTCCCA 1 -- int10--------
    rs1384073801,2
    --12135409(+) AAGAGC/TTGGGA 1 -- int10--------
    rs67014041,2
    C,F,A--12135411(+) GAGCTG/TGGATT 1 -- int19Minor allele frequency- T:0.23NA WA EA 370
    rs1116002941,2
    --12135419(+) ATTACG/AGGTGT 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs726410591,2
    C--12135440(+) GCCTGC/G/TCCGTG 1 -- int11CSA 2
    rs66904931,2
    C,F,A,H--12135526(+) CTTCCG/ATACTC 1 -- int133Minor allele frequency- A:0.49NS EA NA WA CSA 3377
    rs1385380461,2
    --12135549(+) GACTCC/TCTGAC 1 -- int10--------
    rs747983361,2
    --12135631(+) AGAATC/TTCCCA 1 -- int12Minor allele frequency- T:0.06CSA WA 120
    rs801201011,2
    --12135796(+) AGGAGC/TGTCAC 1 -- int12Minor allele frequency- T:0.06CSA WA 120
    rs1180125771,2
    F--12135818(+) AGCATC/TGCCGT 1 -- int11Minor allele frequency- T:0.06EA 120
    rs1492363531,2
    --12135822(+) TCGCCA/GTTTTA 1 -- int10--------
    rs284602691,2
    C,F--12135892(+) CGTCAG/CCATGA 1 -- int15Minor allele frequency- C:0.28WA CSA NA 244
    rs728619461,2
    C,F--12135916(+) ATGACA/TCCTCC 1 -- int15Minor allele frequency- T:0.28WA CSA NA 244
    rs1114407961,2
    --12135970(+) AGCCCT/CGAGAT 1 -- int12Minor allele frequency- C:0.05CSA WA 120
    rs1139002441,2
    --12135978(+) GATAAC/TCTCCC 1 -- int12Minor allele frequency- T:0.04CSA WA 120
    rs1886373831,2
    --12135982(+) ACCTCC/TCCTCT 1 -- int10--------
    rs1917382501,2
    --12136047(+) TAGCCG/TGCGAA 1 -- int10--------
    rs1446189501,2
    --12136049(+) GCCTGC/TGAAAA 1 -- int10--------
    rs2018134121,2
    --12136141(+) TTTAT-/TCTCTTT 1 -- int10--------
    rs1116370621,2
    C,F--12136145(+) ATTCTC/TTTTTT 1 -- int12Minor allele frequency- T:0.50WA NA 4
    rs1410155831,2
    --12136152(+) TTTTT-/TTCTTTTT 1 -- int10--------
    rs1418352851,2
    C--12136155(+) TTTTC-/TTTTTC
    TTTTTTTT
    TTTTT
    1 -- int10--------
    rs559741491,2
    C--12136160(+) TTTTTT/CTTTTT 1 -- int11Minor allele frequency- C:0.00WA 2
    rs1839869981,2
    --12136253(+) CCCGGA/GTTCAA 1 -- int10--------
    rs1484696411,2
    --12136260(+) TCAAGC/TGATTC 1 -- int10--------
    rs1888796721,2
    --12136384(+) ACTCCC/TGACCT 1 -- int10--------
    rs75119071,2
    C,F,A--12136393(+) CTCAGG/ATGATC 1 -- int15Minor allele frequency- A:0.50NA WA 10
    rs1153303311,2
    F--12136499(+) GCCGCT/GTTTCA 1 -- int11Minor allele frequency- G:0.02WA 118
    rs1505731831,2
    --12136614(+) TGTTTC/TCGTGT 1 -- int10--------
    rs115697961,2
    C--12136727(+) CCTGCT/CTGCAG 1 -- int11Minor allele frequency- C:0.01NS 178
    rs1454777251,2
    --12136745(+) ACTGTG/TAGAGG 1 -- int10--------
    rs1911649651,2
    --12136792(+) GATGGC/GTGTGT 1 -- int10--------
    rs115697971,2
    C--12136922(+) TCGGCG/TTGTGG 1 -- int12Minor allele frequency- T:0.02NS WA 296
    rs1836660761,2
    --12136926(+) CGTGTA/GGTGGT 1 -- int10--------
    rs1868601441,2
    --12136952(+) CTTAGG/TAGCGA 1 -- int10--------
    rs1916925711,2
    --12136967(+) GTGGCA/GGTAGA 1 -- int10--------
    rs1849644251,2
    --12136973(+) GTAGAC/TGCATA 1 -- int10--------
    rs115697981,2
    C,F--12136988(+) CCTAAA/GACGTC 1 -- int13Minor allele frequency- G:0.03NS CSA WA 298
    rs115697991,2
    C,F,H--12137065(+) CCAACC/AACGGC 1 -- int16Minor allele frequency- A:0.02NS EA WA 672
    rs1146292101,2
    F--12137079(+) AGAGAT/CTCTCC 1 -- int11Minor allele frequency- C:0.02WA 118
    rs1902042261,2
    --12137099(+) CTCCCC/GAGTCG 1 -- int10--------
    rs1818645001,2
    --12137272(+) CACTTC/TGCCTG 1 -- int10--------
    rs1856082161,2
    --12137289(+) TGTCCA/GCACAT 1 -- int10--------
    rs115698001,2
    C,F--12137311(+) AAACCT/CGATAC 1 -- int13Minor allele frequency- C:0.03NS CSA WA 296
    rs115698011,2
    C,F--12137318(+) ATACTA/GTGGAT 1 -- int13Minor allele frequency- G:0.03NS CSA WA 296
    rs115698021,2
    C--12137359(+) AGGGCG/AGGCCC 1 -- int11Minor allele frequency- A:0.01NS 176
    rs115698031,2
    C--12137360(+) GGGCGG/CGCCCA 1 -- int12Minor allele frequency- C:0.03NS WA 294
    rs115698041,2
    C--12137439(+) AAAGAG/AAGAGA 1 -- int1 trp31Minor allele frequency- A:0.01NS 180
    rs115698051,2
    C,F--12137603(+) AACTGA/CATTCT 1 -- int110Minor allele frequency- C:0.27NS NA WA EA 550
    rs1895579571,2
    --12137682(+) CCTGGA/GTGGGG 1 -- int10--------
    rs115698071,2
    C--12137697(+) TCAGAG/AAGGGC 1 -- int11Minor allele frequency- A:0.01NS 180
    rs115698081,2
    C,F--12137793(+) CAGCAA/C/TGCACA 1 -- int12NS WA 298
    rs1458664271,2
    --12137822(+) GGTGCC/TCGTGG 1 -- int10--------
    rs57724831,2
    C--12137926(+) TTTGGT/-TTTTT 1 -- int1 trp32Minor allele frequency- -:0.25NA CSA 4
    rs1807485331,2
    --12137966(+) TTTCCA/GTATCA 1 -- int10--------
    rs115698091,2
    F--12137989(+) GGCCAT/GGCTAA 1 -- int11Minor allele frequency- G:0.01NS 174
    rs115698101,2
    F--12137991(+) CCATGC/TTAATT 1 -- int11Minor allele frequency- T:0.01NS 174
    rs115698111,2
    C,F,H--12138030(+) GCTATC/TGAAGC 1 -- int16Minor allele frequency- T:0.08NS EA WA 696
    rs1853605821,2
    --12138035(+) CGAAGC/TGAACA 1 -- int10--------
    rs115698121,2
    C,F--12138100(+) TAGGAT/CGGAGG 1 -- int13Minor allele frequency- C:0.03NS CSA WA 296
    rs1490181721,2
    --12138194(+) AGACCC/TTCGGG 1 -- int10--------
    rs115698131,2
    C,F--12138197(+) CCCTCG/AGGTGG 1 -- int13Minor allele frequency- A:0.03NS CSA WA 290
    rs1113514501,2
    --12138297(+) GGTTGG/AGGGCC 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1127403771,2
    --12138337(+) CAGTCT/ACGGCC 1 -- int12Minor allele frequency- A:0.06CSA WA 120
    rs1900231421,2
    --12138349(+) GGCATC/GGTGGC 1 -- int10--------
    rs1129400421,2
    C--12138351(+) CATGGT/AGGCTC 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1413364431,2
    --12138416(+) AGGAGC/TTCGAG 1 -- int10--------
    rs1118330731,2
    C--12138445(+) GTGAAG/ACCCTG 1 -- int11Minor allele frequency- A:0.50WA 2
    rs108645471,2
    C,F,A,H--12138466(+) AAATAT/CAAAAA 1 -- int16Minor allele frequency- C:0.50NA WA CSA 16
    rs1141547711,2
    F--12138494(+) CAAGCG/ACCTGC 1 -- int11Minor allele frequency- A:0.03WA 118
    rs1124810691,2
    --12138602(+) GGCGAC/TGGAGC 1 -- int12Minor allele frequency- T:0.08CSA WA 120
    rs1864913911,2
    --12138608(+) GGAGCA/GAGTAC 1 -- int10--------
    rs120705301,2
    C,F--12138629(+) AAAACA/GAAAAC 1 -- int17Minor allele frequency- G:0.21WA NA CSA EA 366
    rs1917377981,2
    --12138683(+) AGAGCC/TCTGAA 1 -- int10--------
    rs121259731,2
    C,F,A--12138687(+) CCCTGG/AACTAC 1 -- int110Minor allele frequency- A:0.40NA WA CSA EA 372
    rs1153063161,2
    F--12138703(+) CCCCCC/GACCCC 1 -- int11Minor allele frequency- G:0.03NA 120
    rs799624321,2
    --12138753(+) CTGGCC/TCTAAC 1 -- int12Minor allele frequency- T:0.08CSA WA 120
    rs603309501,2
    C,F--12138801(+) CTTACG/ATCTCA 1 -- int14Minor allele frequency- A:0.23WA CSA 124
    rs791789481,2
    --12138818(+) CCCATC/TTGTAA 1 -- int11Minor allele frequency- T:0.01WA 118
    rs1385617471,2
    --12138902(+) TTTCTG/TCTCAG 1 -- int10--------
    rs1411525011,2
    --12138956(+) TAAAAC/TGCAGA 1 -- int10--------
    rs1507309481,2
    --12139014(+) GTGGTA/GCCCCT 1 -- int10--------
    rs1378952591,2
    --12139030(+) TGGCCC/TGGGGC 1 -- int10--------
    rs1495451861,2
    --12139055(+) CAGAGC/TGCACA 1 -- int10--------
    rs1835241721,2
    --12139064(+) CAGCGA/GTGGAG 1 -- int10--------
    rs1472129491,2
    --12139145(+) TTTTGC/TATTTG 1 -- int10--------
    rs1152481751,2
    --12139250(+) ACTGGT/ACTTGT 1 -- int11Minor allele frequency- A:0.01WA 118
    rs1405258761,2
    --12139262(+) GGGAAA/TACCAA 1 -- int10--------
    rs1889143301,2
    --12139348(+) TGGGGC/TGGAGG 1 -- int10--------
    rs1909264191,2
    --12139435(+) CCCCCC/GTCCAG 1 -- int10--------
    rs1820528161,2
    --12139505(+) GGCCCA/GAGCAC 1 -- int10--------
    rs1472743021,2
    --12139784(+) CACCAA/GGTTGA 1 -- int10--------
    rs1487306791,2
    --12139807(+) CCTCCA/GCACAG 1 -- int10--------
    rs1118296491,2
    --12139955(+) TTTACA/GTATAC 1 -- int12Minor allele frequency- G:0.07CSA WA 120
    rs1378824781,2
    --12140006(+) TCTCT-/ATTTTT 1 -- int10--------
    rs1423385481,2
    --12140117(+) TCTCCC/TGCCTC 1 -- int10--------
    rs1512578841,2
    --12140195(+) GAGACA/GGGGTT 1 -- int10--------
    rs1392427921,2
    --12140296(+) CCACCA/GTGCCC 1 -- int10--------
    rs1866415621,2
    --12140386(+) CCATCC/TGGCCG 1 -- int10--------
    rs784692491,2
    F--12140436(+) CTTTGT/CCACAG 1 -- int11Minor allele frequency- C:0.07NA 120
    rs1500679741,2
    --12140556(+) AGAGTG/TGTCGA 1 -- int10--------
    rs596440801,2
    C--12140565(+) GAGCTT/CGTTTC 1 -- int12Minor allele frequency- C:0.08WA 120
    rs121389601,2
    C,F,H--12140588(+) TCTTTC/TGAGGA 1 -- int126Minor allele frequency- N:0.00NS EA NA WA 2674
    rs1466259571,2
    --12140638(+) AGATGG/TAGTTT 1 -- int10--------
    rs75313501,2
    C--12140738(+) gcctcC/Ttgagt 1 -- int10--------
    rs1914443061,2
    --12140755(+) GATTAC/TAGGCA 1 -- int10--------
    rs1848269061,2
    --12140806(+) GAGACA/GGGGTT 1 -- int10--------
    rs66898771,2
    C,F--12140869(+) gtctcA/Cttctc 1 -- int11Minor allele frequency- C:0.08WA 118
    rs1450842441,2
    --12140896(+) ACAGGC/TGTGAG 1 -- int10--------
    rs1468461831,2
    --12140981(+) GGACAC/TGGTGA 1 -- int10--------
    rs1880984891,2
    --12140984(+) CACGGC/TGAAGC 1 -- int10--------
    rs118050001,2
    H--12141016(+) tgctgT/Agtgac 1 -- int14Minor allele frequency- A:0.00NS EA 374
    rs1930570131,2
    --12141077(+) ATGGGA/GTAGTG 1 -- int10--------
    rs1488607851,2
    --12141193(+) CTCTGC/TACCCC 1 -- int10--------
    rs118061761,2
    H--12141235(+) GGAGGA/GAAGCA 1 -- int1 trp30--------
    rs765519581,2
    C,F--12141321(+) ACTCCG/ATAGCT 1 -- int11Minor allele frequency- A:0.03WA 118
    rs1434895471,2
    --12141375(+) AAGGAC/TCCAGA 1 -- int10--------
    rs790361011,2
    --12141389(+) TTCCCA/CCACTC 1 -- int12Minor allele frequency- C:0.08CSA WA 120
    rs726410621,2
    C--12141420(+) CCTCAC/TACCTC 1 -- int10--------
    rs22978751,2
    C,F,A,H--12141461(+) CACCCA/GGTGAG 1 -- int124Minor allele frequency- G:0.43EA NS NA WA CSA 2874
    rs775509031,2
    --12141490(+) ACTTCG