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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TNFRSF6B Gene

protein-coding   GIFtS: 59
GCID: GC20P062326

tumor necrosis factor receptor superfamily, member 6b, decoy
 Explore 46 diseases affiliated with
TNFRSF6B via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TNFRSF6B    

Aliases
for TNFRSF6B gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy1 2     Decoy Receptor 32 3
DCR31 2 3 5     Decoy Receptor For Fas Ligand2 3
M681 2 3     DJ583P15.1.12
TR61 2 3     M68E2
DcR31 3     Tumor Necrosis Factor Receptor Superfamily Member 6B2

External Ids:    HGNC: 119211   Entrez Gene: 87712   Ensembl: ENSG000002435097   OMIM: 6033615   UniProtKB: O954073   

Export aliases for TNFRSF6B gene to outside databases

Previous GC identifers: GC20P062166 GC20U900077 GC20P063052 GC20P063016 GC20P061761 GC20P059059


Summaries
for TNFRSF6B gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TNFRSF6B:
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a
regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with
death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors.
Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere
elongation helicase 1 (RTEL1), generates a non-coding transcript. (provided by RefSeq, Feb 2011)

UniProtKB/Swiss-Prot: TNF6B_HUMAN, O95407
Function: Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects
against apoptosis

Gene Wiki entry for TNFRSF6B


Genomic Views
for TNFRSF6B gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011333.6  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TNFRSF6B gene promoter:
         AP-1   ATF-2   c-Jun   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for TNFRSF6B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TNFRSF6B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.3   Ensembl cytogenetic band:  20q13.33   HGNC cytogenetic band: 20q13.33

TNFRSF6B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TNFRSF6B gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P062326:  view genomic region     (about GC identifiers)

Start:
 62,326,288 bp from pter      End:
 62,330,037 bp from pter
Size:
 3,750 bases      Orientation:
 plus strand

Proteins
for TNFRSF6B gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TNF6B_HUMAN, O95407 (See protein sequence)
Recommended Name: Tumor necrosis factor receptor superfamily member 6B precursor  
Size: 300 amino acids; 32680 Da
Subcellular location: Secreted
3 PDB 3D structures from and Proteopedia for TNFRSF6B:
3K51 (3D)        3MHD (3D)        3MI8 (3D)    

Explore the universe of human proteins at neXtProt for TNFRSF6B: NX_O95407

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O95407

    • TNFRSF6B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_003814.1  
    ENSEMBL proteins: 
     ENSP00000359013  

    Human Recombinant Protein Products: 
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    Novus Biologicals TNFRSF6B Proteins
    Novus Biologicals TNFRSF6B Lysates
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TNFRSF6B

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005615extracellular space NAS10318773
    GO:0005625soluble fraction ----


    TNFRSF6B for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for TNFRSF6B gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TNFRSF6B for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001368 TNFR/NGFR_Cys_rich_reg

    Graphical View of Domain Structure for InterPro Entry O95407

    ProtoNet protein and cluster: O95407

    1 Blocks protein family: IPB001368 TNFR/CD27/30/40/95 cysteine-rich region

    UniProtKB/Swiss-Prot: TNF6B_HUMAN, O95407
    Similarity: Contains 4 TNFR-Cys repeats


    Function
    for TNFRSF6B gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: TNF6B_HUMAN, O95407
    Function: Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects
    against apoptosis

         Genatlas biochemistry entry for TNFRSF6B:
    tumor necrosis factor receptor superfamily,member 6B,binding Fas ligand (TNFRSF6) and inhibiting FasL induced
    apoptosis,amplified in primary lung and colon tumors

    miRNA
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    Inhib. RNA
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    OriGene shRNA RFP: TNFRSF6B
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    Gene Editing
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    Clone
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity TAS9872321
    GO:0005515protein binding IPI10318773


    TNFRSF6B for ontologies           About GeneDecksing



    Pathways & Interactions
    for TNFRSF6B gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Apoptosis and survival_Caspase cascade
    		Apoptosis and survival_FAS signaling cascades0.44
    		Apoptosis and survival FAS signaling cascades0.44
    2TWEAK Pathway
    		Apoptosis through Death Receptors0.32
    		Fas Signaling0.29
    3Apoptosis and Autophagy
    		Apoptosis and Autophagy1.00
    4Apoptosis Modulation and Signaling
    		Apoptosis Modulation and Signaling1.00
    5Rho Family GTPases
    		Molecular Mechanisms of Cancer0.51

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for TNFRSF6B
        Apoptosis and survival FAS signaling cascades

    1 R&D Systems Pathway for TNFRSF6B
        TNF Superfamily - Human Ligand-Receptor Interactions & their Associated Functions

    3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for TNFRSF6B
        Apoptosis through Death Receptors
    Molecular Mechanisms of Cancer
    Fas Signaling

    1 Cell Signaling Technology (CST) Pathway for TNFRSF6B
        Apoptosis and Autophagy

    1 GeneGo (Thomson Reuters) Pathway for TNFRSF6B
        Apoptosis and survival FAS signaling cascades

    1 BioSystems Pathway for TNFRSF6B 
        Apoptosis Modulation and Signaling


    1         Kegg Pathway  (Kegg details for TNFRSF6B):
        Cytokine-cytokine receptor interaction


    TNFRSF6B for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TNFRSF6B

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for TNFRSF6B (O954071, 3 ENSP000003590134) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TNFSF14O435571, 3, ENSP000002459124EBI-524171,EBI-524131 I2D: score=2 STRING: ENSP00000245912
    TNFSF15O951503, ENSP000003631574I2D: score=1 STRING: ENSP00000363157
    FASLGP480233, ENSP000003566944I2D: score=1 STRING: ENSP00000356694
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IEA--
    GO:0043066negative regulation of apoptotic process TAS9872321


    TNFRSF6B for ontologies           About GeneDecksing



    Drugs & Compounds
    for TNFRSF6B gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TNFRSF6B for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TNFRSF6B
    1 Novoseek chemical compound relationship for TNFRSF6B gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    phosphatidylinositol 11.3 3 14688085 (1), 19050262 (1), 14697332 (1)

    Search CenterWatch for drugs/clinical trials and news about TNFRSF6B / TNF6B 

    Transcripts
    for TNFRSF6B gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TNFRSF6B gene (2 alternative transcripts): 
    NM_003823.3  NM_032945.2  

    Unigene Cluster for TNFRSF6B:

    Tumor necrosis factor receptor superfamily, member 6b, decoy
    Hs.744285  [show with all ESTs]
    Unigene Representative Sequence: BQ688727
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000369996

    miRNA
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    Inhib. RNA
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    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TNFRSF6B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TNFRSF6B

    Additional cDNA sequence: 

    AF104419.1 AF134240.1 AF217794.1 AY124378.1 AY124379.1 AY358279.1 BC017065.1 BC034349.1 

    6 DOTS entries:

    DT.101980777  DT.97770485  DT.100026806  DT.99984254  DT.100746777  DT.100746778 

    24/190 AceView cDNA sequences (see all 190):

    AW955349 NM_016434 NM_032957 AY358279 BM784181 AF104419 AU099288 AA326540 
    BM857412 AI857725 AI446656 AI304479 AW135723 BU623385 BF987793 BM756086 
    AY124378 AI380034 NM_003823 BF001490 BE877829 BM784338 AF217795 BE467871 

    GeneLoc Exon Structure


    Expression
    for TNFRSF6B gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TNFRSF6B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACACCCTGTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TNFRSF6B expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 6 LifeMap Cells 
    NameCategory
    PureStem™ endothelial progenitor 30-SM2-1 (Embryonic Progenitor Cell)Endothelium
    PureStem™ endothelial progenitor RP1-MV2-18 (Embryonic Progenitor Cell)Endothelium
    PureStem™ progenitor EN2 (Embryonic Progenitor Cell)
    PureStem™ progenitor EN27 (Embryonic Progenitor Cell)
    PureStem™ progenitor F15 (Embryonic Progenitor Cell)
    PureStem™ progenitor W8 (Embryonic Progenitor Cell)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See TNFRSF6B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TNFRSF6B

    SOURCE GeneReport for Unigene cluster: Hs.744285

    UniProtKB/Swiss-Prot: TNF6B_HUMAN, O95407
    Tissue specificity: Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node,
    trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and
    in SW480 colon carcinoma cells

        SABiosciences Expression via Pathway-Focused PCR Arrays including TNFRSF6B: 
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              Apoptosis 384HT in human mouse rat

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    In Situ
    Assay Products:     
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for TNFRSF6B

    Orthologs
    for TNFRSF6B gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for TNFRSF6B gene from 3/7 species (see all 7)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves TNFRSF6B1 tumor necrosis factor receptor superfamily, member more 64.11(n)
    54.38(a)    		   395096  XM_417434.3  XP_417434.2 
    lizard
    (Anolis carolinensis)    		 Reptilia TNFRSF6B6
    		 --
    		 49(a)
    		 1 ↔ 1
    		 GL343401.1(874091-882568)
    zebrafish
    (Danio rerio)    		 Actinopterygii si:ch1073-210b3.11 si:ch1073-210b3.1 53.11(n)
    37.85(a)    		   407674  XM_002665433.1  XP_002665479.1 


    ENSEMBL Gene Tree for TNFRSF6B (if available)
    TreeFam Gene Tree for TNFRSF6B (if available) 

    Paralogs
    for TNFRSF6B gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TNFRSF6B gene
    TNFRSF212  CD402  TNFRSF1B2  TNFRSF42  TNFRSF11A2  NGFR2  TNFRSF142  TNFRSF11B2  
    LTBR2  TNFRSF92  
    2 SIMAP similar genes for TNFRSF6B using alignment to 4 protein entries:     TNF6B_HUMAN (see all proteins):
    TNFRSF11B    TNFRSF1B

    TNFRSF6B for paralogs           About GeneDecksing



    Genomic Variants
    for TNFRSF6B gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/103 NCBI SNPs in TNFRSF6B are shown (see all 103)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 20 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1405132301,2
    		--62326025(+) AAGGGC/TGGGCA 4 -- us2k1 int10--------
    rs1920605791,2
    		C,--62326077(+) AGCCAC/TGCTAC 4 -- int1 us2k10--------
    rs1825188021,2
    		C,--62326361(+) GGTGGC/GGTGGG 4 -- int1 us2k10--------
    rs2008587961,2
    		--62326364(+) GGGGTG/TGGGGG 4 -- int1 us2k10--------
    rs413099311,2
    		C,F,--62326579(+) GGTAGG/TGCACC 4 -- us2k1 int15Minor allele frequency- T:0.11NA EA EU 1189
    rs2016173541,2
    		--62326580(+) GTAGGA/GCACCT 4 -- us2k1 int10--------
    rs2000089041,2
    		--62326597(+) CTGCTC/TCTGGC 4 -- int1 us2k10--------
    rs2020082771,2
    		--62326655(+) GCCCCC/GCTCAG 4 -- int1 us2k10--------
    rs2022226391,2
    		--62326845(+) CTCATG/TGGAGA 4 -- us2k1 int1 nc-transcript-variant0--------
    rs1444776931,2
    		C,--62326873(+) GGCCAC/TGGGAG 4 -- us2k1 int1 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for TNFRSF6B (62326288 - 62330037 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for TNFRSF6B
         4 CNVs: 35938 0541 4107 30135

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for TNFRSF6B gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TNFRSF6B for disorders           About GeneDecksing

    OMIM gene information: 603361    OMIM disorders: --

    20/46 diseases for TNFRSF6B (see all 46):    About MalaCards
    diffuse large b-cell lymphoma    b-cell lymphomas    oral cavity cancer    crescentic glomerulonephritis
    malignant glioma    esophageal squamous cell carcinoma    systemic lupus erythematosus    squamous cell carcinoma
    lupus erythematosus    inflammatory bowel disease    rheumatoid arthritis    epithelial ovarian cancer
    pituitary adenoma    ulcerative colitis    silicosis    glomerulonephritis
    multiple myeloma    hepatocellular carcinoma    myelodysplastic syndrome    autoimmune hepatitis

    10/23 Novoseek disease relationships for TNFRSF6B gene (see all 23)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    necrosis 56.7 47 15475369 (2), 10318773 (2), 12662434 (1), 18723214 (1) (see all 31)
    tumors 49.8 108 12740925 (6), 10655513 (5), 12899749 (4), 15475369 (4) (see all 48)
    herpes 44.6 6 12566458 (1), 15917993 (1), 17010447 (1), 10318773 (1)
    pancreatic carcinoma 41.2 2 12740925 (1)
    colon adenocarcinoma 40.8 3 14871535 (1), 10318773 (1), 10655513 (1)
    pancreatic cancer 36 12 12794752 (3), 19050262 (2), 11172597 (1), 19466993 (1) (see all 6)
    hepatocellular carcinoma 34 18 12899749 (2), 17493386 (2), 16273601 (2), 19195939 (2) (see all 7)
    cancer 29.9 33 12899749 (2), 15661928 (2), 18349319 (2), 12397645 (1) (see all 19)
    gastric carcinoma 23.8 5 14728836 (2), 12740925 (1), 18991242 (1)
    rheumatoid arthritis 22.6 6 19821006 (2), 18757243 (1), 17393415 (1)

    Human Genome Epidemiology (HuGE) Navigator: TNFRSF6B (16 documents)

    Export disorders for TNFRSF6B gene to outside databases

    Publications
    for TNFRSF6B gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TNFRSF6B gene, integrated from 9 sources (see all 149):
    (articles sorted by number of sources associating them with TNFRSF6B)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis. (PubMed id 10318773)1, 2, 3, 9 Yu K.-Y.... Kwon B.S. (1999)
    2. Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer. (PubMed id 9872321)1, 2, 3, 9 Pitti R.M.... Ashkenazi A. (1998)
    3. Overexpression of M68/DcR3 in human gastrointestinal tract tumors independent of gene amplification and its location in a four-gene cluster. (PubMed id 10655513)1, 2, 9 Bai C.... Caskey C.T. (2000)
    4. Decoy strategies: the structure of TL1A:DcR3 complex. (PubMed id 21300286)1, 2 Zhan C.... Almo S.C. (2011)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    7. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    8. Decoy receptor 3 expression during the menstrual cycle and pregnancy, and regulation by sex steroids in endometrial cells in vitro. (PubMed id 19246462)1, 9 Chen H.F....Ho H.N. (2009)
    9. High DcR3 expression predicts stage pN2-3 in gastric cancer. (PubMed id 18376232)1, 9 Wu Y....Xie Q. (2008)
    10. High DcR3 expression predicts stage pN2 in gastric cancer. (PubMed id 18251184)1, 9 Wu Y....Chen J. (2007)

    External Searches for TNFRSF6B gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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      Query String
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    Genome Databases showing TNFRSF6B gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8771 HGNC: 11921 AceView: TNFRSF6B Ensembl:ENSG00000243509 euGenes: HUgn8771
    ECgene: TNFRSF6B Kegg: 8771 H-InvDB: TNFRSF6B

    Other Databases showing TNFRSF6B gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TNFRSF6B gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TNFRSF6B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TNFRSF6B Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for TNFRSF6B gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TNFRSF6B gene:
    Search GeneIP for patents involving TNFRSF6B

    GeneCards and IP:
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