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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21


protein-coding   GIFtS: 71
GCID: GC01P012161

Tumor Necrosis Factor Receptor Superfamily, Member 1B

(Previous symbol: TNFR2)
Microbiology & Infectious Diseases Congress
  See related diseases

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Tumor Necrosis Factor Receptor Superfamily, Member 1B1 2     TNF-R752
TNFR21 2 3 5     TNFR1B2
TNFBR2 3 5     TNFR802
Tumor Necrosis Factor Receptor 22 3     P75 TNF Receptor2
Tumor Necrosis Factor Receptor Type II2 3     p75TNFR2
TNF-R22 3     Soluble TNFR1B Variant 12
TNF-RII2 3     Tumor Necrosis Factor Beta Receptor2
p752 3     Tumor Necrosis Factor Binding Protein 22
P80 TNF-Alpha Receptor2 3     Tumor Necrosis Factor Receptor Superfamily Member 1B2
CD120b2     Etanercept3
TNF-R-II2     CD120b Antigen3

External Ids:    HGNC: 119171   Entrez Gene: 71332   Ensembl: ENSG000000281377   OMIM: 1911915   UniProtKB: P203333   

Export aliases for TNFRSF1B gene to outside databases

Previous GC identifers: GC01P012291 GC01P012071 GC01P011836 GC01P011936 GC01P011380

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TNFRSF1B Gene:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form
a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3
ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought
to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2,
which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting
neurons from apoptosis by stimulating antioxidative pathways. (provided by RefSeq, Jul 2008)

GeneCards Summary for TNFRSF1B Gene: 
TNFRSF1B (tumor necrosis factor receptor superfamily, member 1B) is a protein-coding gene. Diseases associated with TNFRSF1B include marek disease, and scleritis, and among its related super-pathways are TNF Signaling and STAT3 Pathway. GO annotations related to this gene include tumor necrosis factor-activated receptor activity and ubiquitin protein ligase binding. An important paralog of this gene is TNFRSF21.

UniProtKB/Swiss-Prot: TNR1B_HUMAN, P20333
Function: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for
homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3
to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks
TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological

Gene Wiki entry for TNFRSF1B Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_021937.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TNFRSF1B gene promoter:
         AML1a   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTNFRSF1B promoter sequence
   Search SABiosciences Chromatin IP Primers for TNFRSF1B

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TNFRSF1B

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.22   Ensembl cytogenetic band:  1p36.22   HGNC cytogenetic band: 1p36.22

TNFRSF1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TNFRSF1B gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P012161:  view genomic region     (about GC identifiers)

12,227,060 bp from pter      End:
12,269,285 bp from pter
42,226 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TNR1B_HUMAN, P20333 (See protein sequence)
Recommended Name: Tumor necrosis factor receptor superfamily member 1B precursor  
Size: 461 amino acids; 48291 Da
Subunit: Binds to TRAF2. Interacts with BMX
Subcellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein
Subcellular location: Isoform 2: Secreted
Subcellular location: Tumor necrosis factor-binding protein 2: Secreted
2 PDB 3D structures from and Proteopedia for TNFRSF1B:
1CA9 (3D)        3ALQ (3D)    
Secondary accessions: B1AJZ3 Q16042 Q6YI29 Q9UIH1
Alternative splicing: 2 isoforms:  P20333-1   P20333-2   

Explore the universe of human proteins at neXtProt for TNFRSF1B: NX_P20333

Explore proteomics data for TNFRSF1B at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylated; mainly on serine residues and with a very low level on threonine residues
  • UniProtKB: A soluble form (tumor necrosis factor binding protein 2) is produced from the membrane form by proteolytic
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P20333

  • TNFRSF1B Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TNFRSF1B Protein Expression
    REFSEQ proteins: NP_001057.1  
    ENSEMBL proteins: 
     ENSP00000365435   ENSP00000440425  

    Human Recombinant Protein Products for TNFRSF1B: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for TNFRSF1B (TNF RII/TNFRSF1B)
    Enzo Life Sciences proteins for TNFRSF1B
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for TNFRSF1B
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for TNFRSF1B
    GenScript Custom Purified and Recombinant Proteins Services for TNFRSF1B
    Novus Biologicals TNFRSF1B Proteins
    Novus Biologicals TNFRSF1B Lysates
    Sino Biological Recombinant Protein for TNFRSF1B
    Sino Biological Cell Lysate for TNFRSF1B 
    ProSpec Recombinant Protein for TNFRSF1B
    Cloud-Clone Corp. Proteins for TNFRSF1B 

    Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005634nucleus IEA--
    GO:0005886plasma membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--

    TNFRSF1B for ontologies           About GeneDecksing

    TNFRSF1B Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for TNFRSF1B (TNF RII/TNFRSF1B)
    Cell Signaling Technology (CST) Antibodies for TNFRSF1B  (TNF-R2)
    OriGene Antibodies for TNFRSF1B
    OriGene Custom Antibody Services for TNFRSF1B
    GenScript Custom Superior Antibodies Services for TNFRSF1B
    Novus Biologicals TNFRSF1B Antibodies
    Abcam antibodies for TNFRSF1B
    Cloud-Clone Corp. Antibodies for TNFRSF1B 
    ThermoFisher Antibodies for TNFRSF1B
    LSBio Antibodies in human, mouse, rat for TNFRSF1B 

    Assay Products for TNFRSF1B: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TNFRSF1B
    R&D Systems ELISAs for TNFRSF1B (TNF RII/TNFRSF1B)         (see all)
    GenScript Custom Assay Services for TNFRSF1B
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TNFRSF1B 
    Cloud-Clone Corp. CLIAs for TNFRSF1B

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CD: CD molecules
    TNFRSF: Tumor necrosis factor receptor superfamily

    IUPHAR Guide to PHARMACOLOGY protein family classification: tumor necrosis factor receptor 2 
    Tumour necrosis factor (TNF) receptor family

    2 InterPro protein domains:
     IPR001368 TNFR/NGFR_Cys_rich_reg
     IPR020411 TNFR_1B

    Graphical View of Domain Structure for InterPro Entry P20333

    ProtoNet protein and cluster: P20333

    1 Blocks protein domain: IPB001368 TNFR/CD27/30/40/95 cysteine-rich region

    UniProtKB/Swiss-Prot: TNR1B_HUMAN, P20333
    Similarity: Contains 4 TNFR-Cys repeats

    TNFRSF1B for domains           About GeneDecksing

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TNR1B_HUMAN, P20333
    Function: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for
    homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3
    to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks
    TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological

         Genatlas biochemistry entry for TNFRSF1B:
    tumor necrosis factor receptor superfamily,member 1B,deleted in neuroblastoma,associated with susceptibility to
    systemic lupus erythematosus

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005031tumor necrosis factor-activated receptor activity IEA--
    GO:0005515protein binding IPI10848577
    GO:0031625ubiquitin protein ligase binding IPI11279055
    TNFRSF1B for ontologies           About GeneDecksing

         1 GenomeRNAi human phenotype for TNFRSF1B:
     Decreased Hepatitis C virus re 

         15/19 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Tnfrsf1b) (see all 19):
     adipose tissue  behavior/neurological  cardiovascular system  cellular  digestive/alimentary 
     endocrine/exocrine gland  hematopoietic system  homeostasis/metabolism  immune system  integument 
     liver/biliary system  mortality/aging  muscle  nervous system  renal/urinary system 

    TNFRSF1B for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for TNFRSF1B: Tnfrsf1btm1Imx Tnfrsf1btm1Mwm

       inGenious Targeting Laboratory - Custom generated mouse model solutions for TNFRSF1B 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TNFRSF1B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TNFRSF1B 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TNFRSF1B 

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TNFRSF1B
    8/37 QIAGEN miScript miRNA Assays for microRNAs that regulate TNFRSF1B (see all 37):
    hsa-miR-3938 hsa-let-7d hsa-miR-301a hsa-miR-486-3p hsa-let-7g hsa-let-7a hsa-miR-130b hsa-miR-301b
    SwitchGear 3'UTR luciferase reporter plasmidTNFRSF1B 3' UTR sequence
    Inhib. RNA
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TNFRSF1B
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TNFRSF1B

    Gene Editing
    DNA2.0 Custom Protein Engineering Service for TNFRSF1B
    Sirion Biotech Customized adenovirus for overexpression of TNFRSF1B

    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for TNFRSF1B (see all 7)
    OriGene ORF clones in mouse, rat for TNFRSF1B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TNFRSF1B (NM_001066)
    Sino Biological Human cDNA Clone for TNFRSF1B
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TNFRSF1B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TNFRSF1B
    Sirion Biotech Customized lentivirus for stable overexpression of TNFRSF1B 
                         Customized lentivirus expression plasmids for stable overexpression of TNFRSF1B 

    Cell Line
    GenScript Custom overexpressing Cell Line Services for TNFRSF1B
    Search LifeMap BioReagents cell lines for TNFRSF1B
    In Situ Assay

    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNFRSF1B

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TNFRSF1B About   (see all 30)                                                                                              See pathways by source

    SuperPathContained pathways About
    1TNF Signaling
    TNF Signaling0.50
    TNF Superfamily - Human Ligand-Receptor Interactions & their Associated Functions0.49
    Death Receptor Signaling0.50
    NF-kB (NFkB) Pathway0.46
    2PEDF Induced Signaling
    PGC1Alpha Pathway0.51
    Glucocorticoid Receptor Signaling0.43
    STAT3 Pathway0.47
    Cytokine-cytokine receptor interaction0.43
    3TGF-Beta Pathway
    TGF-Beta Pathway0.60
    JAK-STAT Pathway0.57
    MAPK Family Pathway0.60
    JNK Pathway0.51
    4Akt Signaling
    Akt Signaling0.60
    Tec Kinases Signaling0.55
    p38 Signaling0.60
    5NF-KappaB Family Pathway
    NF-KappaB Family Pathway0.72
    NF-KappaB (p50-p65) Pathway0.72

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    3 EMD Millipore Pathways for TNFRSF1B
        Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway
    Apoptosis and survival Apoptotic TNF-family pathways
    Apoptosis and survival Anti-apoptotic TNFs/NF-kB/IAP pathway

    3 R&D Systems Pathways for TNFRSF1B
        TNF Superfamily - Human Ligand-Receptor Interactions & their Associated Functions
    IL-15 Signaling and its Primary Biological Effects in Different Immune Cell Types
    IL-2 Signaling and its Primary Biological Effects in Different Immune Cell Types

    5/28 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for TNFRSF1B (see all 28)
        Caspase Cascade
    MAPK Signaling
    THC Differentiation Pathway
    TRAF Pathway
    Molecular Mechanisms of Cancer

    2 Cell Signaling Technology (CST) Pathways for TNFRSF1B
        Apoptosis and Autophagy
    NF-kappaB Signaling

    4 GeneGo (Thomson Reuters) Pathways for TNFRSF1B
        Apoptosis and survival Anti-apoptotic TNFs/NF-kB/IAP pathway
    Apoptosis and survival Apoptotic TNF-family pathways
    Transcription NF-kB signaling pathway
    Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway

    5/6 BioSystems Pathways for TNFRSF1B (see all 6)
    Apoptosis Modulation and Signaling
    TNF-alpha/NF-kB Signaling Pathway
    IL-3 Signaling Pathway
    TNF receptor signaling pathway

    3 Sino Biological Pathways for TNFRSF1B 
        TNF Signaling
    Death Receptor Signaling
    NF-kB (NFkB) Pathway

    4         Kegg Pathways  (Kegg details for TNFRSF1B):
        Cytokine-cytokine receptor interaction
    TNF signaling pathway
    Adipocytokine signaling pathway
    Amyotrophic lateral sclerosis (ALS)

    TNFRSF1B for pathways           About GeneDecksing


        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TNFRSF1B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/154 Interacting proteins for TNFRSF1B (P203332, 3 ENSP000003654354) via UniProtKB, MINT, STRING, and/or I2D (see all 154)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000204490P013752, 3, ENSP000003652904MINT-48048 MINT-49370 I2D: score=10 STRING: ENSP00000365290
    TNFP013752, 3, ENSP000003986984MINT-48048 MINT-49370 I2D: score=10 STRING: ENSP00000398698
    ENSG00000228849P013752, 3, ENSP000004106684MINT-48048 MINT-49370 I2D: score=10 STRING: ENSP00000410668
    ENSG00000228321P013752, 3, ENSP000003928584MINT-48048 MINT-49370 I2D: score=10 STRING: ENSP00000392858
    ENSG00000183311P074372, 3MINT-49429 I2D: score=2 
    About this table

    Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process ----
    GO:0006954inflammatory response IEA--
    GO:0006955immune response IEA--
    GO:0007166cell surface receptor signaling pathway ----
    GO:0008219cell death ----

    TNFRSF1B for ontologies           About GeneDecksing

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TNFRSF1B for compounds           About GeneDecksing

    EMD Millipore small molecules for TNFRSF1B:
    Small Molecule - inhibitor
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TNFRSF1B (TNR1B)

    UniProtKB/Swiss-Prot: TNR1B_HUMAN, P20333
    Pharmaceutical: Available under the name Enbrel (Immunex and Wyeth-Ayerst). Used to treat moderate to severe
    rheumatoid arthritis (RA). Enbrel consist of the extracellular ligand-binding portion of TNFRSF1B linked to an
    immunoglobulin Fc chain. It binds to TNF-alpha and blocks its interactions with receptors

    1 DrugBank Compound for TNFRSF1B    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    EtanerceptCD120b (see all 7)185243-69-0target--11752352

    2 IUPHAR Ligands for TNFRSF1B (tumor necrosis factor receptor 2)    About this table 
    LigandTypeActionAffinityPubmed IDs
    tumour necrosis factor membrane form

    10/80 Novoseek inferred chemical compound relationships for TNFRSF1B gene (see all 80)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    etanercept 69.4 34 11574988 (1), 12110156 (1), 16796629 (1), 10904249 (1) (see all 29)
    infliximab 54.4 13 19370184 (2), 12110156 (1), 19136378 (1), 12421092 (1) (see all 10)
    tapi 52.1 4 7869036 (2)
    neopterin 48.3 9 9764776 (2), 15642275 (2), 16273760 (1), 10973464 (1) (see all 6)
    gp 130 41.1 7 10575186 (2), 19631179 (1), 19107325 (1), 10414448 (1) (see all 5)
    il 10 29.6 9 12011375 (3), 8891726 (1), 11508666 (1), 19186969 (1)
    fmlp 29.4 8 7998940 (3), 8946217 (1), 9886420 (1)
    endotoxin 27.9 5 1322942 (1), 7622886 (1), 17244513 (1), 9185243 (1) (see all 5)
    rantes 26.8 8 11562425 (2), 11504986 (2), 10843668 (1), 12376864 (1) (see all 6)
    cuprophan 25.7 2 16988495 (1), 11509797 (1)

    Search CenterWatch for drugs/clinical trials and news about TNFRSF1B / TNR1B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TNFRSF1B gene: 

    Unigene Cluster for TNFRSF1B:

    Tumor necrosis factor receptor superfamily, member 1B
    Hs.256278  [show with all ESTs]
    Unigene Representative Sequence: BC052977
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000376259(uc001att.3 uc009vnk.3) ENST00000492361(uc001atu.3)
    ENST00000489921 ENST00000536782
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TNFRSF1B
    8/37 QIAGEN miScript miRNA Assays for microRNAs that regulate TNFRSF1B (see all 37):
    hsa-miR-3938 hsa-let-7d hsa-miR-301a hsa-miR-486-3p hsa-let-7g hsa-let-7a hsa-miR-130b hsa-miR-301b
    SwitchGear 3'UTR luciferase reporter plasmidTNFRSF1B 3' UTR sequence
    Inhib. RNA
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TNFRSF1B
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TNFRSF1B
    OriGene clones in human, mouse for TNFRSF1B (see all 7)
    OriGene ORF clones in mouse, rat for TNFRSF1B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TNFRSF1B (NM_001066)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TNFRSF1B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TNFRSF1B
    Sirion Biotech Customized lentivirus for stable overexpression of TNFRSF1B 
                         Customized lentivirus expression plasmids for stable overexpression of TNFRSF1B 
    OriGene qPCR primer pairs and template standards for TNFRSF1B
    OriGene qSTAR qPCR primer pairs in human, mouse for TNFRSF1B
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TNFRSF1B
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TNFRSF1B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TNFRSF1B

    Additional mRNA sequence: 

    AY148473.1 BC011844.2 BC042167.1 BC052977.1 BT019927.1 EU826615.1 M32315.1 M35857.1 
    M55994.1 S63368.1 

    7 DOTS entries:

    DT.415651  DT.100823263  DT.100823260  DT.95169202  DT.100823259  DT.100823262  DT.101984571 

    24/183 AceView cDNA sequences (see all 183):

    BQ690571 BU899219 CD610462 BC042167 AA470868 AI140025 AA533208 BU158001 
    CA435681 AI422018 BF222736 BE501344 BE466601 AI916254 NM_001066 AA972749 
    BQ632532 AW468069 BC011844 S63368 CB069666 AI985195 AI632561 AW170706 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TNFRSF1B    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b
    SP1:                                -                                                         
    SP2:                                -                             -     -                     
    SP3:                          -     -                                                         

    ECgene alternative splicing isoforms for TNFRSF1B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TNFRSF1B expression in normal human tissues (normalized intensities)      TNFRSF1B embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    TNFRSF1B Expression
    About this image

    TNFRSF1B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/12 selected tissues (see all 12) fully expand
     Uncategorized (Uncategorized)    fully expand to see all 5 entries
             PureStem Progenitor W10
     Blood (Hematopoietic System)    fully expand to see all 3 entries
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Bone marrow-derived mesenchymal stem cells
             Human Calvarial Osteoblasts (HCO)   
     Mesenchymal Stem Cells
             Bone marrow-derived mesenchymal stem cells
             Human Mesenchymal Stem Cell-hepatic (HMSC-he)   
     Thymus (Hematopoietic System)    fully expand to see all 2 entries
             T Helper Cells Thymus

    See TNFRSF1B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TNFRSF1B

    SOURCE GeneReport for Unigene cluster: Hs.256278
        SABiosciences Expression via Pathway-Focused PCR Arrays including TNFRSF1B (see all 12): 
              HIV Host Response in human mouse rat
              NFKB Signaling Targets in human mouse rat
              Multiple Sclerosis in human mouse rat
              Lymphoma in human mouse rat
              Apoptosis in human mouse rat

    OriGene qPCR primer pairs and template standards for TNFRSF1B
    OriGene qSTAR qPCR primer pairs in human, mouse for TNFRSF1B
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TNFRSF1B
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TNFRSF1B
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TNFRSF1B
    In Situ
    Assay Products:

    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNFRSF1B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for TNFRSF1B gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    Gene Description Human
    (Mus musculus)
    Mammalia Tnfrsf1b1 , 5 tumor necrosis factor receptor superfamily, member more1, 5 74.25(n)1
      4 (78.17 cM)5
    219381  NM_011610.31  NP_035740.21 
    (Gallus gallus)
    Aves TNFRSF1B1 tumor necrosis factor receptor superfamily, member more 48.02(n)
      395083  NM_204439.2  NP_989770.2 
    (Danio rerio)
    Actinopterygii zgc:1630641 zgc:163064 41.4(n)
      100037357  NM_001089510.1  NP_001082979.1 

    ENSEMBL Gene Tree for TNFRSF1B (if available)
    TreeFam Gene Tree for TNFRSF1B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to Build 68)
    About This Section
    Paralogs for TNFRSF1B gene
    3 SIMAP similar genes for TNFRSF1B using alignment to 2 protein entries:     TNR1B_HUMAN (see all proteins):
    TNFR1B    CD40    TNFRSF6B

    TNFRSF1B for paralogs           About GeneDecksing

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1124 SNPs in TNFRSF1B are shown (see all 1124)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    Chr 1 posSequence#AA
    C--11396922(+) TATCT-/ATC   
    1 -- int10--------
    --11396963(+) TTATC-/TATTT 
    1 -- int10--------
    C,F--11401495(+) TCACATG/-AGTGT 1 -- int14Minor allele frequency- -:0.09NS CSA 244
    C--11410251(+) TTTTTT/-CTTTC 1 -- int11Minor allele frequency- -:0.00CSA 2
    C,F--11415953(+) CTACTG/AATAAT 1 -- int18Minor allele frequency- A:0.15NS NA WA EA 630
    C,F,H--11415954(+) TACTGA/CTAATT 1 -- int19Minor allele frequency- C:0.18NS EA NA 664
    C,F--12229032(+) TCCCCC/-GCCTC 1 -- int12Minor allele frequency- -:0.11NS 88
    C,F--12230234(+) CATTCATTC/-  
    1 -- int12Minor allele frequency- -:0.22NS 94
    F--12234229(+) CTTCTC/TCTTCT 1 -- int11Minor allele frequency- T:0.50NA 2
    F--12234235(+) CTTCTC/TCTTCT 1 -- int11Minor allele frequency- T:0.50NA 2

    HapMap Linkage Disequilibrium report for TNFRSF1B (12227060 - 12269285 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for TNFRSF1B:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv508891CNV Insertion20534489
    nsv871537CNV Loss21882294
    nsv527024CNV Loss19592680
    nsv871714CNV Loss21882294
    dgv144n71CNV Loss21882294
    dgv143n71CNV Gain21882294
    nsv871005CNV Gain21882294
    nsv870819CNV Gain21882294
    nsv471622CNV Gain+Loss15918152
    nsv469830CNV Complex16826518

    Human Gene Mutation Database (HGMD): TNFRSF1B
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TNFRSF1B
    DNA2.0 Custom Variant and Variant Library Synthesis for TNFRSF1B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 191191    OMIM disorders: --

    20/182 diseases for TNFRSF1B (see all 182):    About MalaCards
    marek disease    scleritis    palindromic rheumatism    post-transplant lymphoproliferative disease
    guillain-barre syndrome    pneumococcal meningitis    rheumatoid arthritis, association with    mixed connective tissue disease
    paranoid schizophrenia    narcolepsy    hemorrhagic fever with renal syndrome    rheumatic disease
    behcet's disease    microscopic polyangiitis    meningococcal infection    spondylitis
    q fever    hidradenitis    lymphopenia    hidradenitis suppurativa

    18 diseases from the University of Copenhagen DISEASES database for TNFRSF1B:
    Rheumatoid arthritis     Psoriasis     Psoriatic arthritis     Ankylosing spondylitis
    Crohn's disease     Tuberculosis     Hypersensitivity reaction type II disease     Vasculitis
    Uveitis     Arthropathy     Dermatitis     Synovitis
    Exanthem     Hidradenitis suppurativa     Sarcoidosis     adult-onset Still's disease
    Pneumonia     Myositis

    TNFRSF1B for disorders           About GeneDecksing

    Congresses - knowledge worth sharing:  
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    10/93 Novoseek inferred disease relationships for TNFRSF1B gene (see all 93)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    necrosis 88.9 718 7573266 (5), 10561634 (4), 1324217 (3), 1655619 (2) (see all 99)
    tumors 76.6 638 7573266 (5), 9669810 (4), 10561634 (4), 9677439 (3) (see all 99)
    rheumatoid arthritis 63.4 46 9290265 (3), 10765919 (2), 15022314 (2), 15603867 (2) (see all 30)
    inflammation 48.6 18 19343543 (1), 18848768 (1), 11156356 (1), 16947419 (1) (see all 16)
    arthritis psoriatic 45 6 17502870 (1), 19222252 (1), 17394851 (1), 12011375 (1)
    spondylitis ankylosing 43.4 4 19177266 (1), 11986408 (1), 17502870 (1), 17394851 (1)
    fibroma shope 43.3 1 8590321 (1)
    lupus erythematosus systemic 35.6 35 12739039 (3), 11762942 (2), 15642275 (2), 11197692 (2) (see all 18)
    autoimmune diseases 32.2 7 11169260 (4), 17785864 (1), 20225650 (1), 10436260 (1)
    shock septic 31 4 8627066 (1), 11084543 (1), 11253333 (1), 15526005 (1)

    Genetic Association Database (GAD): TNFRSF1B
    Human Genome Epidemiology (HuGE) Navigator: TNFRSF1B (154 documents)

    Export disorders for TNFRSF1B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TNFRSF1B gene, integrated from 9 sources (see all 850) (see top 10):
    (articles sorted by number of sources associating them with TNFRSF1B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Comment: the methionine 196 arginine polymorphism in exon 6 of the TNF receptor 2 gene (TNFRSF1B) is associated with the polycystic ovary syndrome and hyperandrogenism. (PubMed id 12161545)1, 2, 4, 9 Peral B....Escobar-Morreale H.F. (2002)
    2. Association of tumor necrosis factor receptor type II polymorphism 196R with systemic lupus erythematosus in the Japanese: molecular and functional analysis. (PubMed id 11762942)1, 2, 4, 9 Morita C.... Niho Y. (2001)
    3. New single nucleotide polymorphisms in the coding region of human TNFR2: association with systemic lupus erythematosus. (PubMed id 11197692)1, 2, 4, 9 Tsuchiya N.... Tokunaga K. (2000)
    4. Bone structural effects of variation in the TNFRSF1B gene encoding the tumor necrosis factor receptor 2. (PubMed id 18038243)1, 4, 9 Mullin B.H....Wilson S.G. (2008)
    5. The biallelic variable number of tandem repeats of the tumor necrosis factor receptor 2 promoter in systemic lupus erythematosus. (PubMed id 12739039)1, 4, 9 Lee Y.H....Song G.G. (2003)
    6. Tumor necrosis factor receptor 2 gene (TNFRSF1B) in genetic basis of coronary artery disease. (PubMed id 11357933)1, 4, 9 Benjafield A.V....Morris B.J. (2001)
    7. A functional M196R polymorphism of tumour necrosis factor receptor type 2 is associated with systemic lupus erythematosus: a case-control study and a meta-analysis. (PubMed id 17028114)1, 4, 9 Horiuchi T....Harada M. (2007)
    8. Association between TNFRSF1B polymorphisms and bone mineral density, bone loss and fracture. (PubMed id 15071724)1, 4, 9 Tasker P.N....Ralston S.H. (2004)
    9. Single nucleotide polymorphisms in TNF-alpha, TNFR2 g ene and TNF-alpha production in Asian Indians. (PubMed id 19811435)1, 4, 9 Gupta R....Das S.N. (2009)
    10. Polymorphisms of the tumor necrosis factor-alpha receptor 2 gene are associated with obesity phenotypes among 405 Caucasian nuclear families. (PubMed id 18685868)1, 4, 9 Zhao L.J....Deng H.W. (2008)
    11. No association with hypertension of CLCNKB and TNFRSF1B polymorphisms at a hypertension locus on chromosome 1p36. (PubMed id 16003175)1, 4, 9 Speirs H.J....Morris B.J. (2005)
    12. A functional polymorphism of the tumor necrosis factor receptor-II gene associated with the survival and relapse prediction of breast carcinoma. (PubMed id 15863392)1, 4, 9 Mestiri S....Chouchane L. (2005)
    13. Association of polymorphisms of the tumour necrosis factor receptors I and II and rheumatoid arthritis. (PubMed id 12730509)1, 4, 9 Bayley J.P....Verweij C.L. (2003)
    14. Polymorphisms in TNFA and TNFR2 affect outcome of unrelated bone marrow transplantation. (PubMed id 11979305)1, 4, 9 Ishikawa Y....Juji T. (2002)
    15. Possible association of tumor necrosis factor recepto r 2 gene polymorphism with severe hypertension using the extreme discordant phe notype design. (PubMed id 19557004)1, 4, 9 Eguchi T....Saruta T. (2009)
    16. -238 and +489 TNF-alpha along with TNF-RII gene polymorphisms associate with the diffuse phenotype in patients with Systemic Sclerosis. (PubMed id 15585313)1, 4, 9 Tolusso B....Ferraccioli G. (2005)
    17. Polymorphism in the tumour necrosis factor receptor II gene is associated with circulating levels of soluble tumour necrosis factor receptors in rheumatoid arthritis. (PubMed id 16277675)1, 4, 9 Glossop J.R....Mattey D.L. (2005)
    18. Relationship between the tumor necrosis factor receptor II (TNF-RII) gene polymorphism and sTNF-RII plasma levels in healthy controls and in rheumatoid arthritis. (PubMed id 15603867)1, 4, 9 Tolusso B....Ferraccioli G.F. (2004)
    19. Physical mapping and genomic structure of the human TNFR2 gene. (PubMed id 8661109)1, 2, 9 Beltinger C.P....Brodeur G.M. (1996)
    20. The role of tumor necrosis factor (TNF)-alpha and TNF receptor polymorphisms in susceptibility to ankylosing spondylitis. (PubMed id 19772798)1, 4, 9 Chatzikyriakidou A....Drosos A.A. (2009)
    21. Association analysis of TNFRSF1B polymorphisms with type 2 diabetes and its related traits in North India. (PubMed id 19343543)1, 4, 9 Tabassum R....Bharadwaj D. (2009)
    22. A potential role of TNFR gene polymorphisms in autoimmune thyroid diseases in the Tunisian population. (PubMed id 18571427)1, 4, 9 Kammoun-Krichen M....Ayadi H. (2008)
    23. Linkage and association between CA repeat polymorphism of the TNFR2 gene and obesity phenotypes in two independent Caucasian populations. (PubMed id 16980123)1, 4, 9 Huang Q.Y....Deng H.W. (2006)
    24. Anemia in rheumatoid arthritis: association with polymorphism in the tumor necrosis factor receptor I and II genes. (PubMed id 16142859)1, 4, 9 Glossop J.R....Mattey D.L. (2005)
    25. Tumor necrosis factor receptor gene polymorphisms in Crohn's disease: association with clinical phenotypes. (PubMed id 15842589)1, 4, 9 Waschke K.A....Wild G.E. (2005)
    26. TNFR2 gene polymorphism in coronary artery disease. (PubMed id 15805680)1, 4, 9 Sankar V.H....Agrawal S. (2005)
    27. [Potential effect of tumor necrosis factor-alpha and tumor necrosis factor receptor II gene polymorphisms on the pathogenesis of silicosis.] (PubMed id 15555301)1, 4, 9 Li L....Liu B.C. (2004)
    28. [Potential effect of tumor necrosis factor-alpha and its receptor II gene polymorphisms on the pathogenesis of coal worker's pneumoconiosis] (PubMed id 15355698)1, 4, 9 Li L....Wang H.L. (2004)
    29. Tumour necrosis factor-alpha polymorphism and the HLA-Cw*0602 allele in psoriatic arthritis. (PubMed id 12011375)1, 4, 9 Al-Heresh A.M....McHugh N. (2002)
    30. Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: role in endothelial cell migration and angiogenesis. (PubMed id 12370298)1, 2, 9 Pan S....Min W. (2002)
    31. Tumor necrosis factor receptor 2 polymorphism in systemic lupus erythematosus: no association with disease. (PubMed id 11600223)1, 4, 9 Lee E.B....Song Y.W. (2001)
    32. Association between rheumatoid arthritis and polymorphism of tumor necrosis factor receptor II, but not tumor necrosis factor receptor I, in Caucasians. (PubMed id 11212177)1, 4, 9 Barton A....Worthington J. (2001)
    33. Tumor necrosis factor receptor-II: heritability and effect on brain morphology in schizophrenia. (PubMed id 11126399)1, 4, 9 Wassink T.H....Andreasen N.C. (2000)
    34. Biochemical properties of the 75-kDa tumor necrosis factor receptor. Characterization of ligand binding, internalization, and receptor phosphorylation. (PubMed id 1328224)1, 2, 9 Pennica D.... Goeddel D.V. (1992)
    35. Polymorphism of interleukin-10 promoter and tumor necrosis factor receptor II in Vietnamese patients with systemic lupus erythematosus. (PubMed id 15674653)1, 4, 9 Khoa P.D....Yokochi T. (2005)
    36. Tumor necrosis factor receptor II gene polymorphism and severity of rheumatoid arthritis. (PubMed id 15022314)1, 4, 9 Constantin A....Cantagrel A. (2004)
    37. Genetic contribution of tumor necrosis factor (TNF)-alpha gene promoter (-1031, -863 and -857) and TNF receptor 2 gene polymorphisms in endometriosis susceptibility. (PubMed id 15212671)1, 4, 9 Teramoto M....Honjo H. (2004)
    38. Association of tumor necrosis factor receptor type 2 +587 gene polymorphism with severe chronic periodontitis. (PubMed id 15142217)1, 4, 9 Shimada Y....Yamazaki K. (2004)
    39. No association between tumour necrosis factor receptor type 2 gene polymorphism and rheumatoid arthritis severity: a comparison of the extremes of phenotypes. (PubMed id 15252214)1, 4, 9 van der Helm-van Mil A.H....Huizinga T.W. (2004)
    40. Tumor necrosis factor receptor 2 microsatellite and exon 6 polymorphisms in rheumatoid arthritis in Taiwan. (PubMed id 12610797)1, 4, 9 Yen J.H....Liu H.W. (2003)
    41. Association between tumor necrosis factor receptor II and familial, but not sporadic, rheumatoid arthritis: evidence for genetic heterogeneity. (PubMed id 12209506)1, 4, 9 Dieude P....Cornelis F. (2002)
    42. TNFRSF1B in genetic predisposition to clinical neuropathy and effect on HDL cholesterol and glycosylated hemoglobin in type 2 diabetes. (PubMed id 11315843)1, 4, 9 Benjafield A.V....Morris B.J. (2001)
    43. Analysis of tumor necrosis factor-alpha, lymphotoxin-alpha, tumor necrosis factor receptor II, and interleukin-6 polymorphisms in patients with idiopathic pulmonary fibrosis. (PubMed id 11371414)1, 4, 9 Pantelidis P....Du Bois R.M. (2001)
    44. Tumor necrosis factor, tumor necrosis factor receptors type 1 and 2, lymphotoxin-alpha, and HLA-DRB1 gene polymorphisms in human T-cell lymphotropic virus type I associated myelopathy. (PubMed id 11163081)1, 4, 9 Nishimura M....Uchiyama T. (2000)
    45. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor. (PubMed id 8069916)1, 2, 9 Rothe M.... Goeddel D.V. (1994)
    46. A functional haplotype in the 3'untranslated region o f TNFRSF1B is associated with tuberculosis in two African populations. (PubMed id 20007930)1, 4, 9 MAPller M....Franke A. (2010)
    47. Polymorphisms spanning the TNFR2 and TACE genes do no t contribute towards variable anti-TNF treatment response. (PubMed id 20300049)1, 4, 9 Potter C....Barton A. (2010)
    48. Cigarette smoking, STAT4 and TNFRSF1B polymorphisms, and systemic lupus erythematosus in a Japanese population. (PubMed id 19684152)1, 4, 9 Kiyohara C....Takahashi H. (2009)
    49. Tumor necrosis factor (TNF)-TNF receptor gene polymorphisms and their serum levels in Korean women with endometriosis. (PubMed id 19238748)1, 4, 9 Chae S.J....Kim J.G. (2008)
    50. Influence of FCGR3A-V212F and TNFRSF1B-M196R genotypes in patients with rheumatoid arthritis treated with infliximab therapy. (PubMed id 18565259)1, 4, 9 Rooryck C....Schaeverbeke T. (2008)
    51. Association of TNF-alpha and TNFR1 promoters and 3' UTR region of TNFR2 gene polymorphisms with genetic susceptibility to tobacco-related oral carcinoma in Asian Indians. (PubMed id 18206417)1, 4, 9 Gupta R....Das S.N. (2008)
    52. Variable number of tandem repeats of TNF receptor type 2 promoter as genetic biomarker of susceptibility to develop invasive pulmonary aspergillosis. (PubMed id 17207711)1, 4, 9 Sainz J....Jurado M. (2007)
    53. Tumor necrosis factor receptor 2 M196R polymorphism in rheumatoid arthritis and osteoarthritis: relationship with sTNFR2 levels and clinical features. (PubMed id 16871413)1, 4, 9 Oregon-Romero E....Munoz-Valle J.F. (2006)
    54. Tumour necrosis factor receptors (TNFRs) in Type 2 diabetes. Analysis of soluble plasma fractions and genetic variations of TNFR2 gene in a case-control study. (PubMed id 15787661)1, 4, 9 Vendrell J....Richart C. (2005)
    55. Tumour necrosis factor-alpha receptor 1 and 2 polymorphisms in inflammatory bowel disease and their association with response to infliximab. (PubMed id 15274667)1, 4, 9 Pierik M....Rutgeerts P. (2004)
    56. A TNFR1 genotype with a protective role in familial rheumatoid arthritis. (PubMed id 14872483)1, 4, 9 Dieude P....Cornelis F. (2004)
    57. TNF and TNFR polymorphisms in severe sepsis and septic shock: a prospective multicentre study. (PubMed id 15526005)1, 4, 9 Gordon A.C....Hinds C.J. (2004)
    58. Genetic variants in the tumor necrosis factor receptor II gene in patients with multiple sclerosis. (PubMed id 14651520)1, 4, 9 Ehling R....Berger T. (2004)
    59. The influence of genetic variation in the HLA-DRB1 and LTA-TNF regions on the response to treatment of early rheumatoid arthritis with methotrexate or etanercept. (PubMed id 15457442)1, 4, 9 Criswell L.A....Bridges S.L. (2004)
    60. Polymorphisms of the tumor necrosis factor receptors: no association with narcolepsy in German patients. (PubMed id 12601524)1, 4, 9 Wieczorek S....Gencik M. (2003)
    61. TNF and TNF receptor polymorphisms in Korean Behcet's disease patients. (PubMed id 12770792)1, 4, 9 Lee E.B....Song Y.W. (2003)
    62. No association of polymorphisms in the tumor necrosis factor receptor I and receptor II genes with disease severity in rheumatoid arthritis. (PubMed id 12858434)1, 4, 9 Glossop J.R....Mattey D.L. (2003)
    63. Tumour necrosis factor receptor type II 196M/R genotype correlates with circulating soluble receptor levels in normal subjects and with graft-versus-host disease after sibling allogeneic bone marrow transplantation. (PubMed id 14688526)1, 4, 9 Stark G.L....Middleton P.G. (2003)
    64. Association analysis of bone mineral density and single nucleotide polymorphisms in two candidate genes on chromosome 1p36. (PubMed id 14565595)1, 4, 9 Spotila L.D....Devoto M. (2003)
    65. Tumor necrosis factor-alpha receptor II polymorphism in patients from southern Europe with mild-moderate and severe rheumatoid arthritis. (PubMed id 12233877)1, 4, 9 Fabris M....Ferraccioli G. (2002)
    66. Tumour necrosis factor receptor II polymorphism and juvenile idiopathic arthritis. (PubMed id 11961180)1, 4, 9 Zeggini E....Donn R. (2002)
    67. Lack of association between the Met196Arg polymorphism in the TNFR2 gene and autoimmune diseases accompanied by vasculitis including SLE in Japanese. (PubMed id 11169260)1, 4, 9 Takahashi M....Kimura A. (2001)
    68. Case-control study with narcoleptic patients and healthy controls who, like the patients, possess both HLA-DRB1*1501 and -DQB1*0602. (PubMed id 11285131)1, 4, 9 Hohjoh H....Tokunaga K. (2001)
    69. Structural basis for self-association and receptor recognition of human TRAF2. (PubMed id 10206649)1, 2, 9 Park Y.C.... Wu H. (1999)
    70. Physiogenomic analysis of statin-treated patients: do main-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PubMed id 20602615)1, 4 RuaA+o G....Wu A.H. (2010)
    71. Genetic variants in inflammation-related genes are as sociated with radiation-induced toxicity following treatment for non-small cell lung cancer. (PubMed id 20811626)1, 4 Hildebrandt M.A....Wu X. (2010)
    72. Common single nucleotide polymorphisms in immunoregul atory genes and multiple myeloma risk among women in Connecticut. (PubMed id 20568250)1, 4 Lee K.M....Lan Q. (2010)
    73. Common polymorphisms in ITGA2, PON1 and THBS2 are ass ociated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population. (PubMed id 20485444)1, 4 Wang Y....Huang W. (2010)
    74. Lack of association between tumour necrosis factor re ceptor types 1 and 2 gene polymorphism and severe acute alcoholic hepatitis. (PubMed id 19641466)1, 4 Nguyen-Khac E....Naassila M. (2010)
    75. Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility 'hot-spot'. (PubMed id 20628624)1, 4 Johnatty S.E.... . (2010)
    76. Interleukin-9 polymorphism in infants with respirator y syncytial virus infection: an opposite effect in boys and girls. (PubMed id 20503287)1, 4 Schuurhof A....Janssen R. (2010)
    77. TNFRSF1B A1466G genotype is predictive of clinical ef ficacy after treatment with a definitive 5-fluorouracil/cisplatin-based chemora diotherapy in Japanese patients with esophageal squamous cell carcinoma. (PubMed id 20646319)1, 4 Kuwahara A....Sakaeda T. (2010)
    78. SNP/haplotype associations in cytokine and cytokine r eceptor genes and immunity to rubella vaccine. (PubMed id 20217072)1, 4 Dhiman N....Poland G.A. (2010)
    79. The IFNG (IFN-gamma) genotype predicts cytogenetic an d molecular response to imatinib therapy in chronic myeloid leukemia. (PubMed id 20959405)1, 4 Kim D.H....Lipton J.H. (2010)
    80. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    81. Tumor necrosis factor-alpha gene polymorphisms are as sociated with severity of acute graft-versus-host disease following matched unr elated donor bone marrow transplantation in children: a Pediatric Blood and Mar row Transplant Consortium study. (PubMed id 20100586)1, 4 Goyal R.K....Atlas M. (2010)
    82. Genetic variability in the severity and outcome of co mmunity-acquired pneumonia. (PubMed id 19900796)1, 4 SolAc-ViolA!n J....Rodriguez-Gallego C. (2010)
    83. Identification of fetal and maternal single nucleotid e polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. (PubMed id 20452482)1, 4 Romero R....Menon R. (2010)
    84. A genetic association study of maternal and fetal can didate genes that predispose to preterm prelabor rupture of membranes (PROM). (PubMed id 20673868)1, 4 Romero R....Menon R. (2010)
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    86. Genetic Risk Profiling And Prediction Of Disease Course In Crohn'S Disease Patients. (PubMed id 19422935)1, 4 Henckaerts L....Vermeire S. (2009)
    87. Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort. (PubMed id 19174780)1, 4 Weersma R.K....Vermeire S. (2009)
    88. Determination of genetic predisposition to patent ductus arteriosus in preterm infants. (PubMed id 19336370)1, 4 Dagle J.M....Murray J.C. (2009)
    89. Racial disparity in pathophysiologic pathways of pret erm birth based on genetic variants. (PubMed id 19527514)1, 4 Menon R....Thorsen P. (2009)
    90. Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. (PubMed id 19258923)1, 4 Siezen C.L....Janssen R. (2009)
    91. Multiple osteoporosis susceptibility genes on chromosome 1p36 in Chinese. (PubMed id 19442614)1, 4 Huang Q.Y....Kung A.W. (2009)
    92. Genetic risk factors for periodontitis in a Japanese population. (PubMed id 19892918)1, 4 Kobayashi T....Yoshie H. (2009)
    93. High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PubMed id 19453261)1, 4 Yerges L.M....Zmuda J.M. (2009)
    94. Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (2009)
    95. Combination of TNF-RII, CYP1A1 and GSTM1 polymorphism s and the risk of Japanese SLE: findings from the KYSS study. (PubMed id 19561157)1, 4 Horiuchi T....Takahashi H. (2009)
    96. Assessment of 14 functional gene polymorphisms in Jap anese patients with oral lichen planus: a pilot case-control study. (PubMed id 19497711)1, 4 Fujita H....Yoshie H. (2009)
    97. Association between polymorphisms in tumor necrosis factor (TNF) and TNF receptor genes and circulating TNF, soluble TNF receptor levels, and bone mineral density in postmenopausal Korean women. (PubMed id 19369902)1, 4 Kim H....Kim J.G. (2009)
    98. Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit. (PubMed id 19050632)1, 4 Henckaerts L....Van den Berghe G. (2009)
    99. Does the simultaneous tumor necrosis factor receptor 2, tumor necrosis factor promoter gene polymorphism represent a higher risk for alcoholic liver disease? (PubMed id 19212208)1, 4 Machado M.V....Cortez-Pinto H. (2009)
    100. Tumor Necrosis Factor Receptor Superfamily, Member 1B Haplotypes Increase or Decrease the Risk of Inflammatory Bowel Diseases in a New Zealand Caucasian Population. (PubMed id 19421420)1, 4 Ferguson L.R....Demmers P.S. (2009)
    101. Genetic variants in the candidate genes of the apoptosis pathway and susceptibility to chronic myeloid leukemia. (PubMed id 19141860)1, 4 Kim D.H....Lipton J.H. (2009)
    102. Role of inflammation gene polymorphisms on pain sever ity in lung cancer patients. (PubMed id 19773451)1, 4 Reyes-Gibby C.C....Shete S. (2009)
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    104. Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants. (PubMed id 18818748)1, 4 Velez D.R....Menon R. (2008)
    105. Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia. (PubMed id 19074885)1, 4 Enjuanes A....Campo E. (2008)
    106. Genetic regulation of amniotic fluid TNF-alpha and soluble TNF receptor concentrations affected by race and preterm birth. (PubMed id 18807256)1, 4 Menon R....Williams S.M. (2008)
    107. Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. (PubMed id 19019335)1, 4 Velez D.R....Menon R. (2008)
    108. The tumour necrosis factor receptor superfamily member 1b 676T>G polymorphism in relation to response to infliximab and adalimumab treatment and disease severity in rheumatoid arthritis. (PubMed id 18385279)1, 4 Toonen E.J....Barrera P. (2008)
    109. Genetic polymorphisms of tumour necrosis factor receptor superfamily 1A and 1B affect responses to infliximab in Japanese patients with Crohn's disease. (PubMed id 18248655)1, 4 Matsukura H....Muramatsu M. (2008)
    110. Can tumor necrosis factor receptor II gene 676T>G polymorphism predict the response grading to anti-TNFalpha therapy in rheumatoid arthritis? (PubMed id 18309487)1, 4 Ongaro A....Padovan M. (2008)
    111. Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma. (PubMed id 18636124)1, 4 Skibola C.F....Smith M.T. (2008)
    112. Multiple genetic factors in olanzapine-induced weight gain in schizophrenia patients: a cohort study. (PubMed id 19193342)1, 4 Ujike H....Kuroda S. (2008)
    113. Contribution of PTPN22 1858T, TNFRII 196R and HLA-shared epitope alleles with rheumatoid factor and anti-citrullinated protein antibodies to very early rheumatoid arthritis diagnosis. (PubMed id 18535030)1, 4 Goeb V....Vittecoq O. (2008)
    114. Racial disparity in maternal-fetal genetic epistasis in spontaneous preterm birth. (PubMed id 18538149)1, 4 Fortunato S.J....Williams S.M. (2008)
    115. Associations between cytokine/cytokine receptor single nucleotide polymorphisms and humoral immunity to measles, mumps and rubella in a Somali population. (PubMed id 18715339)1, 4 Dhiman N....Poland G.A. (2008)
    116. TNF receptor I polymorphism is associated with persistent palindromic rheumatism. (PubMed id 17763205)1, 4 Lu L.Y....Sung P.K. (2007)
    117. TNF polymorphisms in psoriasis: association of psoriatic arthritis with the promoter polymorphism TNF*-857 independent of the PSORS1 risk allele. (PubMed id 17530646)1, 4 Reich K....Burkhardt H. (2007)
    118. Polymorphism of genes related to cardiovascular disease in patients with rheumatoid arthritis. (PubMed id 18173921)1, 4 Arlestig L....Rantapaa-Dahlqvist S. (2007)
    119. Polymorphisms in 33 inflammatory genes and risk of myocardial infarction--a system genetics approach. (PubMed id 17634906)1, 4 Barbaux S....Cambien F. (2007)
    120. Epistatic interactions between genomic regions containing the COL1A1 gene and genes regulating osteoclast differentiation may influence femoral neck bone mineral density. (PubMed id 17331078)1, 4 Yang T.L....Deng H.W. (2007)
    121. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. (PubMed id 17703412)1, 4 Janssen R....Hoebee B. (2007)
    122. Inflammation and atherosclerosis: the role of TNF and TNF receptors polymorphisms in coronary artery disease. (PubMed id 17346438)1, 4 Sbarsi I....Cuccia M. (2007)
    123. CA repeat polymorphism of the TNFR2 gene is not associated with bone mineral density in two independent Caucasian populations. (PubMed id 16502120)1, 4 Huang Q.Y....Deng H.W. (2006)
    124. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    125. Multilocus interactions at maternal tumor necrosis factor-alpha, tumor necrosis factor receptors, interleukin-6 and interleukin-6 receptor genes predict spontaneous preterm labor in European-American women. (PubMed id 16731080)1, 4 Menon R....Fortunato S.J. (2006)
    126. TNF-857T, a genetic risk marker for acute anterior uveitis. (PubMed id 15851552)1, 4 Kuo N.W....Lightman S. (2005)
    127. Physical function and its response to exercise: associations with cytokine gene variation in older adults with knee osteoarthritis. (PubMed id 16282562)1, 4 Nicklas B.J....Pahor M. (2005)
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    129. Complex genetic predisposition in adult and juvenile rheumatoid arthritis. (PubMed id 15018649)1, 4 Miterski B....Epplen J.T. (2004)
    130. Identification of single nucleotide polymorphisms in the tumor necrosis factor (TNF) and TNF receptor superfamily in the Korean population. (PubMed id 15301860)1, 4 Cho S.M....Lee J.K. (2004)
    131. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    132. Promoter polymorphisms of tumor necrosis factor-alpha are associated with risk of gastric mucosa-associated lymphoid tissue lymphoma. (PubMed id 15146559)1, 4 Wu M.S....Lin J.T. (2004)
    133. Identification and characterization of a novel spliced variant that encodes human soluble tumor necrosis factor receptor 2. (PubMed id 14688072)1, 2 Lainez B.... Engel P. (2004)
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    135. Influence of cytokine and mannose binding protein gene polymorphisms on human T-cell leukemia virus type I (hTLV-I) provirus load in HTLV-I asymptomatic carriers. (PubMed id 12651071)1, 4 Nishimura M....Matsuoka M. (2003)
    136. Tumour necrosis factor family genes in a phenotype of COPD associated with emphysema. (PubMed id 12661999)1, 4 Ferrarotti I....Luisetti M. (2003)
    137. Genetic background of Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis: association of HLA-DRB1*0901 with microscopic polyangiitis. (PubMed id 12858454)1, 4 Tsuchiya N....Hashimoto H. (2003)
    138. Polymorphisms of the TNF gene and the TNF receptor superfamily member 1B gene are associated with susceptibility to ulcerative colitis and Crohn's disease, respectively. (PubMed id 11904678)1, 4 Sashio H....Furuyama J. (2002)
    139. Linkage disequilibrium between polymorphisms in the human TNFRSF1B gene and their association with bone mass in perimenopausal women. (PubMed id 12217957)1, 4 Albagha O.M....Ralston S.H. (2002)
    140. Pharmacogenetic investigation of the TNF/TNF-receptor system in patients with chronic active Crohn's disease treated with infliximab. (PubMed id 12049175)1, 4 Mascheretti S....Schreiber S. (2002)
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    146. A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor. (PubMed id 2172983)1, 2 Kohno T.... Vannice J.L. (1990)
    147. Two human TNF receptors have similar extracellular, but distinct intracellular, domain sequences. (PubMed id 1966549)1, 2 Dembic Z.... Lesslauer W. (1990)
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    151. Casein kinase-1 phosphorylates the p75 tumor necrosis factor receptor and negatively regulates tumor necrosis factor signaling for apoptosis. (PubMed id 7559483)1, 9 Beyaert R....Fiers W. (1995)
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    155. Overexpression of TNF-alpha and TNFRII in invasive micropapillary carcinoma of the breast: clinicopathological correlations. (PubMed id 18764880)1, 9 Cui L.F....Fu L. (2008)
    156. Deficient expression of tumor necrosis factor receptor type 2 in the endometrium of women with endometriosis. (PubMed id 14506926)1, 9 Kharfi A....Akoum A. (2003)
    157. Significant association of the tumor necrosis factor receptor 2 (TNFR2) gene with human narcolepsy. (PubMed id 11144293)1, 9 Hohjoh H....Tokunaga K. (2000)
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    161. Interferon beta-1a Induces tumor necrosis factor receptor 1 but decreases tumor necrosis factor receptor 2 leukocyte mRNA levels in relapsing-remitting multiple sclerosis. (PubMed id 19246939)1, 9 Reuss R....Oschmann P. (2009)
    162. Interaction between transmembrane TNF and TNFR1/2 mediates the activation of monocytes by contact with T cells. (PubMed id 17785864)1, 9 Rossol M....Wagner U. (2007)
    163. Granulocyte macrophage-colony stimulating factor and interleukin-3 increase expression of type II tumour necrosis factor receptor, increasing susceptibility to tumour necrosis factor-induced apoptosis. Control of leukaemia cell life/death switching. (PubMed id 15459750)1, 9 Rae C. and MacEwan D.J. (2004)
    164. The death domain of tumor necrosis factor receptor 1 is necessary but not sufficient for Golgi retention of the receptor and mediates receptor desensitization. (PubMed id 10950109)1, 9 Gaeta M.L....Pober J.S. (2000)
    165. Ankyrin repeat and SOCS box 3 (ASB3) mediates ubiquitination and degradation of tumor necrosis factor receptor II. (PubMed id 15899873)1, 9 Chung A.S.... Chin Y.E. (2005)
    166. Polymorphism of the tumor necrosis factor-alpha receptor 2 gene is associated with obesity, leptin levels, and insulin resistance in young subjects and diet-treated type 2 diabetic patients. (PubMed id 10841005)4, 9 Fernandez-Real J.M....Richart C. (2000)
    167. Association of tumor necrosis factor receptor 2 (TNFR2) polymorphism with susceptibility to systemic lupus erythematosus. (PubMed id 10395102)4, 9 Komata T....Tokunaga K. (1999)
    168. Expression and functional significance of tumor necrosis factor receptors in human myocardium. (PubMed id 7664431)1, 9 Torre-Amione G....Mann D.L. (1995)
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    173. Thalidomide and its analogues have distinct and opposing effects on TNF-alpha and TNFR2 during co-stimulation of both CD4(+) and CD8(+) T cells. (PubMed id 12296856)1, 9 Marriott J.B....Dalgleish A.G. (2002)
    174. Analysis of the association of HLA-DRB1, TNFalpha promoter and TNFR2 (TNFRSF1B) polymorphisms with SLE using transmission disequilibrium test. (PubMed id 11607787)4, 9 Tsuchiya N....Tokunaga K. (2001)
    175. The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor. (PubMed id 11244088)1, 9 Wooten M.W.... Moscat J. (2001)
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    192. TNFR1- and TNFR2-mediated signaling pathways in human kidney are cell type-specific and differentially contribute to renal injury. (PubMed id 16195372)1, 9 Al-Lamki R.S....Bradley J.R. (2005)
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    195. Independent contribution of HLA-DRB1 and TNF alpha promoter polymorphisms to the susceptibility to Crohn's disease. (PubMed id 11196680)4, 9 Kawasaki A....Tokunaga K. (2000)
    196. Tumor necrosis factor receptor II (TNFRII) exon 6 polymorphism in systemic lupus erythematosus. (PubMed id 10703622)4, 9 Al-Ansari A.S....Hajeer A.H. (2000)
    197. A TNFR2 3' flanking region polymorphism in systemic lupus erythematosus. (PubMed id 11196716)4, 9 Sullivan K.E....Petri M.A. (2000)
    198. TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activation. (PubMed id 10764746)1, 9 Pype S.... Remacle J.E. (2000)
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    223. A positive correlation between hydrogen peroxide and s oluble TNF-alpha receptor 2 early in maternal blood and at term in placenta of p regnant women with preeclampsia. (PubMed id 21174572)1 Leblanc S....Aris A. (2012)
    224. Salivary cortisol and soluble tumor necrosis factor-a receptor II responses to multiple experimental modalities of acute pain. (PubMed id 21895688)1 Goodin B.R....McGuire L. (2012)
    225. Myometrial tumor necrosis factor-a receptors increase with gestation and labor and modulate gene expression through mitogen-activated kinase and nuclear factor-kB. (PubMed id 22228740)1 Alexander H.A....Johnson M.R. (2012)
    226. NF-kappaB signal triggering and termination by tumor necrosis factor receptor 2. (PubMed id 21558270)1 RodrA-guez M....Lazo P.S. (2011)
    227. TNFR2 - target for therapeutics against neurodegenera tive diseases? (PubMed id 21153362)1 Nijholt I.M....Eisel U.L. (2011)
    228. Tumor necrosis factor-I+ signaling via TNFR1/p55 is de leterious whereas TNFR2/p75 signaling is protective in adult infarct myocardium . (PubMed id 21153348)1 Kishore R....Goukassian D.A. (2011)
    229. TNFR2 interposes the proliferative and NF-I_B-mediated inflammatory response by podocytes to TNF-I+. (PubMed id 21221075)1 Bruggeman L.A....Nelson P.J. (2011)
    230. TNFR1 and TNFR2 regulate the extrinsic apoptotic path way in myeloma cells by multiple mechanisms. (PubMed id 21850048)1 Rauert H....Siegmund D. (2011)
    231. Lower frequency of CD62L(high) and higher frequency o f TNFR2(+) Tregs are associated with inflammatory conditions in type 1 diabetic patients. (PubMed id 21584225)1 Ryba M....MyA9liwska J. (2011)
    232. A TNF receptor 2 selective agonist rescues human neuro ns from oxidative stress-induced cell death. (PubMed id 22110694)1 Fischer R....Pfizenmaier K. (2011)
    233. Necdin and neurotrophin receptors: interactors of rel evance for neuronal resistance to oxidant stress. (PubMed id 21150695)1 Ingraham C.A....Schor N.F. (2011)
    234. The effect of P75 on Trk receptors in neuroblastomas. (PubMed id 21419569)1 Ho R....Brodeur G.M. (2011)
    235. TNFRSF1B +676 T>G polymorphism predicts survival o f non-small cell lung cancer patients treated with chemoradiotherapy. (PubMed id 21995493)1 Guan X....Wei Q. (2011)
    236. Cytokine induction of tumor necrosis factor receptor 2 is mediated by STAT3 in colon cancer cells. (PubMed id 21994466)1 Hamilton K.E....Lund P.K. (2011)
    237. Evaluation of serum level of tumor necrosis factor rec eptor II in hepatitis C virus (genotype 4)-infected middle-aged men with and wit hout diabetes and its complications in Egypt: a pilot study. (PubMed id 22068019)1 Said E.S....Mosaad N.A. (2011)
    238. The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. (PubMed id 21393509)1 Tang W....Liu C.J. (2011)
    239. Polymorphism of 3'UTR region of TNFR2 coding gene and its role in clinical tuberculosis in Han Chinese pediatric population. (PubMed id 21554999)1 Mokrousov I....Shen A. (2011)
    240. Tumor necrosis factor-a levels correlate with postoper ative pain severity in lumbar disc hernia patients: opposite clinical effects be tween tumor necrosis factor receptor 1 and 2. (PubMed id 21920667)1 Andrade P....Hoogland G. (2011)
    241. Critical role of tumor necrosis factor receptor 1, bu t not 2, in hepatic stellate cell proliferation, extracellular matrix remodelin g, and liver fibrogenesis. (PubMed id 21523796)1 Tarrats N....MarA- M. (2011)
    242. Human lymphatic filariasis: genetic polymorphism of e ndothelin-1 and tumor necrosis factor receptor II correlates with development o f chronic disease. (PubMed id 21673044)1 Panda A.K....Satapathy A.K. (2011)
    243. Association of tumor necrosis factor alpha and its re ceptor polymorphisms with rheumatoid arthritis in female patients. (PubMed id 21777909)1 Hussein Y.M....Alzahrani S.S. (2011)
    244. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    245. No association of TNFRSF1B variants with type 2 diabe tes in Indians of Indo-European origin. (PubMed id 21849023)1 Tabassum R....Bharadwaj D. (2011)
    246. Association between serum soluble TNFI+ receptors and renal dysfunction in type 2 diabetic patients without proteinuria. (PubMed id 21288590)1 Miyazawa I....Maegawa H. (2011)
    247. Association of anti-CCP positivity and carriage of TN FRII susceptibility variant with anti-TNF-I+ response in rheumatoid arthritis. (PubMed id 21813066)1 Vasilopoulos Y....Mamouris Z. (2011)
    248. Tumor necrosis factor-receptor 2 and TROY gene express ion patterns in cutaneous squamous cell carcinoma in a Tunisian population. (PubMed id 22057614)1 Zidi I.T....Nouira R.B. (2011)
    249. TNFR 2 M196R polymorphism and acne vulgaris in Han Ch inese: a case-control study. (PubMed id 20556591)1 Tian L....Wang W. (2010)
    250. Soluble TNF receptors are associated with AI^ metaboli sm and conversion to dementia in subjects with mild cognitive impairment. (PubMed id 19070941)1 Buchhave P....Hansson O. (2010)
    251. Plasma soluble tumour necrosis factor-alpha receptor 2 is elevated in obesity: specific contribution of visceral adiposity. (PubMed id 19650780)1 Cartier A....DesprAcs J.P. (2010)
    252. Altered expression of TNF-alpha signaling pathway pro teins in systemic lupus erythematosus. (PubMed id 20516030)1 Zhu L.J....Wither J.E. (2010)
    253. Endothelial-specific transgenesis of TNFR2 promotes a daptive arteriogenesis and angiogenesis. (PubMed id 20395596)1 Luo Y....Min W. (2010)
    254. Tumor necrosis factor alpha and its soluble receptors in obese children with NAFLD. (PubMed id 20371430)1 Lebensztejn D.M....Kaczmarski M. (2010)
    255. Association of the Met-196-Arg Variation of Human Tum or Necrosis Factor Receptor 2 (TNFR2) with Paranoid Schizophrenia. (PubMed id 20842464)1 Thabet S....Bel Hadj Jrad B. (2010)
    256. Relationship between TNFA, TNFB and TNFRII gene polym orphisms and outcome after unrelated hematopoietic cell transplantation in a Ch inese population. (PubMed id 20548340)1 Xiao H.W....Huang H. (2010)
    257. Levels of salivary IFN-gamma, TNF-alfa, and TNF recep tor-2 as prognostic markers in (erosive) oral lichen planus. (PubMed id 21403886)1 Ghallab N.A....Shaker O.G. (2010)
    258. TNF activates a NF-kappaB-regulated cellular program in human CD45RA- regulatory T cells that modulates their suppressive function. (PubMed id 20181891)1 Nagar M....Goldstein I. (2010)
    259. Association analysis of TNFR2, VDR, A2M, GSTT1, GSTM1 , and ACE genes with rheumatoid arthritis in South Asians and Caucasians of Eas t Midlands in the United Kingdom. (PubMed id 20401725)1 Ghelani A.M....Mastana S.S. (2010)
    260. Elevated levels of soluble TNF receptors 1 and 2 corr elate with Plasmodium falciparum parasitemia in pregnant women: potential marke rs for malaria-associated inflammation. (PubMed id 20980627)1 ThAcvenon A.D....Taylor D.W. (2010)
    261. [Gene polymorphism of tumor necrosis factor-alpha rec eptor II in 196 site and premature births in Chinese Han Population] (PubMed id 20369486)1 Pu J. and Zeng W.Y. (2010)
    262. Generation of mouse macrophages expressing membrane-b ound TNF variants with selectivity for TNFR1 or TNFR2. (PubMed id 20045350)1 Shibata H....Tsutsumi Y. (2010)
    263. Impact of genomic risk factors on outcome after hemat opoietic stem cell transplantation for patients with chronic myeloid leukemia. (PubMed id 20305143)1 Dickinson A.M....Gratwohl A. (2010)
    264. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)4 Israni A....Oetting W.S. (2010)
    265. Association Study of Tumor Necrosis Factor Receptor T ype 2 M196R and Toll-Like Receptor 2 Arg753Gln Polymorphisms with Acne Vulgaris in a Chinese Han Ethnic Group. (PubMed id 20861605)1 Tian L.M....Wang W.Z. (2010)
    266. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
    267. The association of tumor necrosis factor alpha recept or 2 and tumor necrosis factor alpha with insulin resistance and the influence of adipose tissue biomarkers in humans. (PubMed id 19846171)1 Hivert M.F....Meigs J.B. (2010)
    268. Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients. (PubMed id 19262425)1 Bowes J.D....Barton A. (2009)
    269. MEK, p38, and PI-3K mediate cross talk between EGFR a nd TNFR in enhancing hepatocyte growth factor production from human mesenchymal stem cells. (PubMed id 19692652)1 Wang Y....Meldrum D.R. (2009)
    270. Circulating levels of TNF-alpha and its soluble recep tors in the plasma of patients with epithelial ovarian cancer. (PubMed id 19825522)1 Dobrzycka B....Kinalski M. (2009)
    271. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    272. Plasma concentrations of TNF-alpha and its soluble re ceptors sTNFR1 and sTNFR2 in patients with coronary artery disease. (PubMed id 19845893)1 Safranow K....Chlubek D. (2009)
    273. Monogenic and polygenic models detected in steroid 21-hydroxylase deficiency-related paediatric hyperandrogenism. (PubMed id 19039234)4 Ezquieta B....BellA^n J.M. (2009)
    274. Serum levels of TNF-alpha, TNF-alphaRI, TNF-alphaRII and IL-12 in treated rheumatoid arthritis patients. (PubMed id 19801788)1 Ebrahimi A.A....Ghojazadeh M. (2009)
    275. Genetic analysis of Alzheimer's disease in the Uppsala Longitudinal Study of Adult Men. (PubMed id 19141999)4 Giedraitis V....Glaser A. (2009)
    276. Similar immune profile in bipolar disorder and schizo phrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor. (PubMed id 19839997)1 Hope S....Andreassen O.A. (2009)
    277. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    278. TNFR gene-modified mesenchymal stem cells attenuate inflammation and cardiac dysfunction following MI. (PubMed id 17852784)1 Bao C....Hu Z. (2008)
    279. Soluble tumour necrosis factor receptors sTNFR1 and sTNFR2 are produced at sites of inflammation and are markers of arthritis activity in Behcet's disease. (PubMed id 18415772)1 Turan B....Villiger P.M. (2008)
    280. Comparing Type D personality and older age as correlates of tumor necrosis factor-alpha dysregulation in chronic heart failure. (PubMed id 18068948)1 Denollet J....Conraads V.M. (2008)
    281. Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis. (PubMed id 18593464)1 Jin P.... Paleolog E.M. (2008)
    282. Selective death of autoreactive T cells in human diabetes by TNF or TNF receptor 2 agonism. (PubMed id 18755894)1 Ban L....Faustman D.L. (2008)
    283. Oxidative stress promotes ligand-independent and enhanced ligand-dependent tumor necrosis factor receptor signaling. (PubMed id 18544535)1 Ozsoy H.Z....Mann D.L. (2008)
    284. Increased serum levels of inflammatory markers in chronic institutionalized patients with schizophrenia. (PubMed id 18679053)1 Coelho F.M....Teixeira A.L. (2008)
    285. The role of IL-12 and TNF-alpha in AIDP and AMAN. (PubMed id 18717726)1 Deng H....Zhu J. (2008)
    286. Simple and highly sensitive assay system for TNFR2-mediated soluble- and transmembrane-TNF activity. (PubMed id 18417150)1 Abe Y....Tsutsumi Y. (2008)
    287. Smurf2 is a TRAF2 binding protein that triggers TNF-R2 ubiquitination and TNF-R2-induced JNK activation. (PubMed id 18671942)1 Carpentier I....Beyaert R. (2008)
    288. Soluble tumor necrosis factor (TNF) receptors (sTNF-R1 and -R2) in pregnant women chronically infected with Trypanosoma cruzi and their children. (PubMed id 18337349)1 Garcia M.M....Cardoni R.L. (2008)
    289. Negative regulation of constitutive NF-kappaB and JNK signaling by PKN1-mediated phosphorylation of TRAF1. (PubMed id 18429822)1 Kato T....Ono Y. (2008)
    290. Cytokine levels of TGF-beta, IL-10, and sTNFalphaRII in type C chronic liver disease. (PubMed id 18080762)1 Verma V....Kar P. (2008)
    291. Tumour necrosis factor receptor 2 (TNFRSF1B) association study in Sjogren's syndrome. (PubMed id 17998218)1 Miceli-Richard C....Mariette X. (2007)
    292. Protein and gene expression of tumour necrosis factor receptors I and II and their promoter gene polymorphisms in Alzheimer's disease. (PubMed id 17267158)1 Culpan D....Wilcock G.K. (2007)
    293. Combined tumour necrosis factor-alpha and tumour necro sis factor receptor genotypes could predict rheumatoid arthritis patients' respo nse to anti-TNF-alpha therapy and explain controversies of studies based on a si ngle polymorphism. (PubMed id 17409133)4 Chatzikyriakidou A....Drosos A.A. (2007)
    294. Soluble vascular cell adhesion molecule-1 is independently associated with soluble tumor necrosis factor receptor 2 in Japanese type 2 diabetic patients. (PubMed id 17258924)1 Nabeya D....Seino Y. (2007)
    295. Genetic disregulation of TNF alpha and TNF alpha type II receptors in colon cancer at the II and III stage of disease. (PubMed id 18088549)1 Muc-Wierzgon M....Wierzgon J. (2006)
    296. Divergent relationships among soluble tumor necrosis factor-alpha receptors 1 and 2, insulin resistance, and endothelial function. (PubMed id 16732051)1 Esteve E....Fernandez-Real J.M. (2006)
    297. An alternatively spliced soluble TNF-alpha receptor is associated with metabolic disorders: a replication study. (PubMed id 16979382)1 Fernandez-Real J.M....Delgado E. (2006)
    298. Soluble tumor necrosis factor receptor 2 is independently associated with brachial-ankle pulse-wave velocity in nonobese Japanese type 2 diabetic patients. (PubMed id 16732050)1 Ohgushi M....Seino Y. (2006)
    299. HIV-1 gp120 up-regulation of the mu opioid receptor in TPA-differentiated HL-60 cells. (PubMed id 16846840)1 Beltran J.A....Chang S.L. (2006)
    300. An alternative spliced variant of circulating soluble tumor necrosis factor-alpha receptor-2 is paradoxically associated with insulin action. (PubMed id 16645020)1 Fernandez-Real J.M....Ricart W. (2006)
    301. Impact of infliximab on serum leptin levels in patients with Crohn's disease. (PubMed id 15784704)1 Franchimont D....Van Gossum A. (2005)
    302. The (CA)n polymorphism of the TNFR2 gene is associated with peak bone density in Chinese nuclear families. (PubMed id 15886863)1 Xu H....Deng H.W. (2005)
    303. A prospective study of soluble tumor necrosis factor-alpha receptor II (sTNF-RII) and risk of coronary heart disease among women with type 2 diabetes. (PubMed id 15920055)1 Shai I....Hu F.B. (2005)
    304. Up-regulation of soluble tumor necrosis factor receptor two in plasma of HIV-seropositive individuals who use opiates. (PubMed id 15000697)1 Ryan L.A....Zheng J. (2004)
    305. Genetic disregulation of gene coding tumor necrosis factor alpha receptors (TNFalpha Rs) in colorectal cancer cells. (PubMed id 15743036)1 Muc-Wierzgon M....Sosada K. (2004)
    306. A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. (PubMed id 14743216)1 Bouwmeester T....Superti-Furga G. (2004)
    307. NAK is recruited to the TNFR1 complex in a TNFalpha-dependent manner and mediates the production of RANTES: identification of endogenous TNFR-interacting proteins by a proteomic approach. (PubMed id 15485837)1 Kuai J.... Lin L.-L. (2004)
    308. Tumor necrosis factor (TNF)alpha and its soluble receptor (sTNFR) p75 during acute human parvovirus B19 infection in children. (PubMed id 12880679)1 Barash J....Hahn T. (2003)
    309. Distinct regulation of cytosolic phospholipase A2 phosphorylation, translocation, proteolysis and activation by tumour necrosis factor-receptor subtypes. (PubMed id 12786601)1 Jupp O.J....MacEwan D.J. (2003)
    310. [A study on early activation of T lymphocytes and soluble tumor necrosis factor receptor in patients with myelodysplastic syndrome] (PubMed id 14728878)1 Shen R....Li J. (2003)
    311. TL1A-induced NF-kappaB activation and c-IAP2 production prevent DR3-mediated apoptosis in TF-1 cells. (PubMed id 12882979)1 Wen L....Wei P. (2003)
    312. Soluble tumor necrosis factor-alpha receptors in young obese subjects with normal and impaired glucose tolerance. (PubMed id 12610052)1 Dzienis-Straczkowska S....Kinalska I. (2003)
    313. A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses. (PubMed id 14532286)1 Chan F.K....Lenardo M.J. (2003)
    314. Elevated serum levels of the type I and type II receptors for tumor necrosis factor-alpha as predictive factors for ARF in patients with septic shock. (PubMed id 12500222)1 Iglesias J....Levine J.S. (2003)
    315. Serum levels of soluble TNF-alpha receptor-II (P75), circulating gammadelta T-cells and Adamantiades-Behcet's disease activity. (PubMed id 12918703)1 Elezoglou A.V....Kaklamanis P.G. (2003)
    316. Genetic disregulation of gene coding tumor necrosis factor alpha receptors (TNF alpha Rs) in follicular thyroid cancer--preliminary report. (PubMed id 12144133)1 Zubelewicz B....Podwinska E. (2002)
    317. Role of TNF/TNFR in autoimmunity: specific TNF receptor blockade may be advantageous to anti-TNF treatments. (PubMed id 12220546)1 Kollias G. and Kontoyiannis D. (2002)
    318. TTD: Therapeutic Target Database. (PubMed id 11752352)7 Chen X....Chen Y.Z. (2002)
    319. Increased sensitivity of T lymphocytes to tumor necrosis factor receptor 1 (TNFR1)- and TNFR2-mediated apoptosis in HIV infection: relation to expression of Bcl-2 and active caspase-8 and caspase-3. (PubMed id 11861282)1 de Oliveira Pinto L.M....Gougeon M.L. (2002)
    320. Genetic approaches to the investigation of rheumatoid arthritis. (PubMed id 11981324)4 Barton A. and Ollier W. (2002)
    321. Elevation of serum eosinophil cationic protein, soluble tumor necrosis factor receptors and soluble intercellular adhesion molecule-1 levels in acute bronchial asthma. (PubMed id 12530121)1 Kokuludag A....Sebik F. (2002)
    322. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    323. Shedding of TNF-alpha receptors, blood pressure, and insulin sensitivity in type 2 diabetes mellitus. (PubMed id 11882518)1 Fernandez-Real J.M....Ricart W. (2002)
    324. The emerging distinct role of TNF-receptor 2 (p80) signaling in chronic inflammatory disorders. (PubMed id 12371624)1 Holtmann M.H....Neurath M.F. (2002)
    325. An update on genetic studies of systemic lupus erythematosus. (PubMed id 12126589)4 Tsao B.P. (2002)
    326. A mammalian homolog of Drosophila schnurri, KRC, regulates TNF receptor-driven responses and interacts with TRAF2. (PubMed id 11804591)1 Oukka M....Glimcher L.H. (2002)
    327. Increased plasma-soluble tumor necrosis factor-alpha receptor 2 level in lean nondiabetic offspring of type 2 diabetic subjects. (PubMed id 12351485)1 Straczkowski M....Kinalska I. (2002)
    328. Plasma interleukin-8 concentrations are increased in obese subjects and related to fat mass and tumor necrosis factor-alpha system. (PubMed id 12364441)1 Straczkowski M....Kinalska I. (2002)
    329. Relationships between fibrinolytic and inflammatory parameters in human adipose tissue: strong contribution of TNFalpha receptors to PAI-1 levels. (PubMed id 12353079)1 Bastelica D....Alessi M.C. (2002)
    330. Role of TNF receptor-associated factor 2 in the activation of IgM secretion by CD40 and CD120b. (PubMed id 11907088)1 Hostager B.S. and Bishop G.A. (2002)
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    332. Human milk anti-inflammatory component contents during acute mastitis. (PubMed id 11520075)1 Buescher E.S. and Hair P.S. (2001)
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    337. Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4. (PubMed id 9744279)1 Herbein G....Verdin E. (1998)
    338. Decreased trkA neurotrophin receptor expression in the parietal cortex of patients with Alzheimer's disease. (PubMed id 9507943)1 Hock C....Otten U. (1998)
    339. Differential activities of secreted lymphotoxin-alpha3 and membrane lymphotoxin-alpha1beta2 in lymphotoxin-induced inflammation: critical role of TNF receptor 1 signaling. (PubMed id 9552007)1 Sacca R....Ruddle N.H. (1998)
    340. Tumor necrosis factor receptor (TNFR)-associated factor 2A (TRAF2A), a TRAF2 splice variant with an extended RING finger domain that inhibits TNFR2-mediated NF-kappaB activation. (PubMed id 9461607)1 Brink R. and Lodish H.F. (1998)
    341. TRAF-interacting protein (TRIP): a novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation. (PubMed id 9104814)1 Lee S.Y.... Choi Y. (1997)
    342. Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily. (PubMed id 9168896)1 Boucher L.-M.... Mak T.W. (1997)
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    346. I-TRAF is a novel TRAF-interacting protein that regulates TRAF- mediated signal transduction. (PubMed id 8710854)1 Rothe M....Goeddel D.V. (1996)
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    366. Interleukin-10 upregulates tumor necrosis factor receptor type-II (p75) gene expression in endotoxin-stimulated human monocytes. (PubMed id 9354687)9 Dickensheets H.L....Donnelly R.P. (1997)
    367. Nerve growth factor and its monocyte receptors are affected in kidney disease. (PubMed id 19169037)9 Antonucci M.T....Aloe L. (2009)
    368. Expression of tumor necrosis factor receptors on gran ulocytes in patients with myeloperoxidase anti-neutrophil cytoplasmic autoantib ody-associated vasculitis. (PubMed id 19690440)9 Hasegawa M....Sugiyama S. (2009)
    369. The low-affinity neurotrophin receptor, p75, is upregulated in ganglioneuroblastoma/ganglioneuroma and reduces tumorigenicity of neuroblastoma cells in vivo. (PubMed id 19142969)9 Schulte J.H....Eggert A. (2009)
    370. Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors. (PubMed id 17196528)9 Wehrman T.... Garcia K.C. (2007)
    371. Cytokine profile in Egyptian hepatitis C virus genotype-4 in relation to liver disease progression. (PubMed id 16425355)9 Zekri A.R....Abu-Shady M.A. (2005)
    372. Tumor necrosis factor-receptor 2 is up-regulated on lamina propria T cells in Crohn's disease and promotes experimental colitis in vivo. (PubMed id 12555659)9 Holtmann M.H....Neurath M.F. (2002)
    373. The p75 neurotrophin receptor and neuronal apoptosis. (PubMed id 10704998)9 Barrett G.L. (2000)
    374. Soluble tumor necrosis factor receptors in sera from patients with insulin-dependent diabetes mellitus: relations to duration and complications of disease. (PubMed id 10436260)9 Kulseng B....Espevik T. (1999)
    375. Antioestrogens enhance tumour necrosis factor receptor 2 (TNF-R2) expression and TNF-R2-mediated proliferation in activated T cells. (PubMed id 9743209)9 Komi J. and Lassila O. (1998)
    376. Increased serum concentrations of soluble tumor necrosis factor receptors p55 and p75 in early onset neonatal sepsis. (PubMed id 9808075)9 Doellner H....Austgulen R. (1998)
    377. Ligand-induced formation of p55 and p75 tumor necrosis factor receptor heterocomplexes on intact cells. (PubMed id 9099731)9 Pinckard J.K....Schreiber R.D. (1997)
    378. Soluble tumor necrosis factor receptors are present in human vitreous and shed by retinal pigment epithelial cells. (PubMed id 8943704)9 Sippy B.D....Hinton D.R. (1996)
    379. TNF-induced superoxide anion production in adherent human neutrophils involves both the p55 and p75 TNF receptor. (PubMed id 7706751)9 Richter J....Lantz M. (1995)
    380. Soluble tumor necrosis factor receptors in maternal plasma and second-trimester amniotic fluid. (PubMed id 7573266)9 Kupferminc M.J....Socol M.L. (1995)
    381. Molecular cloning of porcine (Sus scrofa) tumor necrosis factor receptor 2. (PubMed id 17827878)9 Cheng Y....Manabe N. (2007)
    382. Tumor necrosis factor receptor 2 (TNFR2) signaling is negatively regulated by a novel, carboxyl-terminal TNFR-associated factor 2 (TRAF2)-binding site. (PubMed id 16020544)9 Grech A.P....Brink R. (2005)
    383. Hypoxic upregulation of TNF receptor type 2 expression involves NF-IL-6 and is independent of HIF-1 or HIF-2. (PubMed id 11576469)9 Hehlgans T....Mannel D.N. (2001)
    384. Serum soluble tumor necrosis factor-alpha receptor 2 is elevated in obesity but is not related to insulin sensitivity: a study in id entical twins discordant for obesity. (PubMed id 10946872)9 RAPnnemaa T....Kaprio J. (2000)
    385. Linkage and association of tumor necrosis factor receptor 2 locus with hypertension, hypercholesterolemia and plasma shed receptor. (PubMed id 10942422)9 Glenn C.L....Morris B.J. (2000)
    386. The 75-kD tumour necrosis factor (TNF) receptor is specifically up-regulated in monocytes during Q fever endocarditis. (PubMed id 10931145)9 Ghigo E....Mege J. (2000)
    387. Prognostic significance of tumor necrosis factors and their receptors in nonsmall cell lung carcinoma. (PubMed id 9669810)9 Tran T.A....Ross J.S. (1998)
    388. Enhanced downregulation of the p75 nerve growth factor receptor by cholesteryl and bis-cholesteryl antisense oligonucleotides. (PubMed id 9918113)9 Epa W.R....Barrett G.L. (1998)
    389. TNF receptors in the microvascular pathology of acute respiratory distress syndrome and cerebral malaria. (PubMed id 9129203)9 Lucas R....Grau G.E. (1997)
    390. Characterization of different soluble TNF receptor (TNFR80) derivatives: positive influence of the intracellular domain on receptor/ligand interaction and TNF neutralization capacity. (PubMed id 8807502)9 Moosmayer D....Pfizenmaier K. (1996)
    391. Creation of lysine-deficient mutant lymphotoxin-alpha with receptor selectivity by using a phage display system. (PubMed id 19853911)9 Yoshioka Y....Nakagawa S. (2010)
    392. Upregulation of TNF receptor type 2 in human and experimental renal allograft rejection. (PubMed id 19298452)9 Hoffmann U....KrAomer B.K. (2009)
    393. MEK mediates the novel cross talk between TNFR2 and T GF-EGFR in enhancing vascular endothelial growth factor (VEGF) secretion from h uman mesenchymal stem cells. (PubMed id 19628074)9 Wang Y....Meldrum D.R. (2009)
    394. Anti-inflammatory effects of tumour necrosis factor (TNF)-alpha are mediated via TNF-R2 (p75) in tolerogenic transforming growth factor-beta-treated antigen-presenting cells. (PubMed id 18795974)9 Masli S. and Turpie B. (2009)
    395. TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal gamma-secretase-mediated release of the p75 intracellular domain. (PubMed id 17215246)9 Urra S....Bronfman F.C. (2007)
    396. Distinct effects of p75 in mediating actions of neurotrophins on basal forebrain oligodendrocytes. (PubMed id 16356734)9 Du Y....Dreyfus C.F. (2006)
    397. IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction. (PubMed id 17030185)9 Wang F....Turner J.R. (2006)
    398. Lovastatin stimulates p75 TNF receptor (TNFR2) expression in primary human endothelial cells. (PubMed id 16273297)9 Nubel T....Fritz G. (2005)
    399. Aortic aneurysm repair is associated with a lower inflammatory response compared with surgery for inflammatory bowel disease. (PubMed id 15359089)9 Oldenburg H.S....Moldawer L.L. (2004)
    400. Function and regulation of tumor necrosis factor type 2. (PubMed id 15279559)9 Carpentier I....Beyaert R. (2004)
    401. Chronic ethanol enhances ectodomain shedding in T cells and monocytes. (PubMed id 15365312)9 Zhao X.J....Kolls J.K. (2004)
    402. Tumor necrosis factor receptor 2 mRNA in rat models of hypertension. (PubMed id 12878376)9 Lin R.C....Morris B.J. (2003)
    403. Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis. (PubMed id 11756498)9 Harrington A.W....Yoon S.O. (2002)
    404. Distribution of TNF-alpha, TNF-R55 and TNF-R75 in the rheumatoid synovial membrane: TNF receptors are localized preferentially in the lining layer; TNF-alpha is distributed mainly in the vicinity of TNF receptors in the deeper layers. (PubMed id 10102645)9 Alsalameh S....Kinne R.W. (1999)
    405. The tumor necrosis factor alpha and its soluble receptor profile in term and preterm parturition. (PubMed id 10561634)9 Maymon E....Romero R. (1999)
    406. The mouse tumor necrosis factor receptor 2 gene: genomic structure and characterization of the two transcripts. (PubMed id 9740674)9 Hurle B....Lazo P.S. (1998)
    407. A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF-R. (PubMed id 9763613)9 Douni E. and Kollias G. (1998)
    408. Nuclear degeneration in the developing lens and its regulation by TNFalpha. (PubMed id 9533864)9 Wride M.A. and Sanders E.J. (1998)
    409. Membrane tumor necrosis factor (TNF) induced cooperative signaling of TNFR60 and TNFR80 favors induction of cell death rather than virus production in HIV-infected T cells. (PubMed id 8996244)9 Lazdins J.K....Pfizenmaier K. (1997)
    410. Tumor necrosis factor ligand-receptor system can predict treatment outcome in lymphoma patients. (PubMed id 9053471)9 Warzocha K....Coiffier B. (1997)
    411. Tumor necrosis factor (TNF) up-regulates the expression of p75 but not p55 TNF receptors, and both receptors mediate, independently of each other, up-regulation of transforming growth factor alpha and epidermal growth factor receptor mRNA. (PubMed id 8381414)9 Kalthoff H....Schmiegel W. (1993)
    412. Tumor necrosis factor activates human endothelial cells through the p55 tumor necrosis factor receptor but the p75 receptor contributes to activation at low tumor necrosis factor concentration. (PubMed id 7504889)9 Slowik M.R....Pober J.S. (1993)
    413. Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-kappa B is differentially regulated in human monocytic cells. (PubMed id 1634604)9 Kaufman P.A....Greene W.C. (1992)
    414. Immunodetection of NGF, trkA, p75 and inhibin alpha-s ubunit in interstitial cells of golden hamsters treated with hCG. (PubMed id 19809221)9 Weng Q....Taya K. (2009)
    415. Localization of the low-affinity nerve growth factor receptor p75 in human limbal epithelial cells. (PubMed id 19210757)9 Di Girolamo N....Wakefield D. (2008)
    416. Evaluation of soluble tumour necrosis factor alpha receptors p55 and p75 in ovarian cancer patients. (PubMed id 15754999)9 Opala T....Wozniak J. (2005)
    417. Differential expression, shedding, cytokine regulation and function of TNFR1 and TNFR2 in human fetal astrocytes. (PubMed id 16385659)9 Choi S.J....Park J.Y. (2005)
    418. p75-nerve growth factor as an antiapoptotic complex: independence versus cooperativity in protection from enediyne chemotherapeutic agents. (PubMed id 11901208)9 Yan C....Schor N.F. (2002)
    419. Differential activation of nuclear factor-kappaB by tumour necrosis factor receptor subtypes. TNFR1 predominates whereas TNFR2 activates transcription poorly. (PubMed id 11943206)9 McFarlane S.M....MacEwan D.J. (2002)
    420. Moderate-intensity regular exercise decreases serum tumor necrosis factor-alpha and HbA1c levels in healthy women. (PubMed id 11033992)9 Tsukui S....Kobayashi I. (2000)
    421. Tumor necrosis factor-alpha and tumor necrosis factor receptor I, II levels in patients with severe burns. (PubMed id 10741589)9 Yamada Y....Sato S. (2000)
    422. Hepatic stellate cells express the low affinity nerve growth factor receptor p75 and undergo apoptosis in response to nerve growth factor stimulation. (PubMed id 10751349)9 Trim N....Iredale J. (2000)
    423. Cutting edge: a dominant negative form of TNF-alpha converting enzyme inhibits proTNF and TNFRII secretion. (PubMed id 10510344)9 Solomon K.A....Newton R.C. (1999)
    424. Preferential expression of tumor necrosis factor receptor 55 (TNF-R55) on human articular chondrocytes: selective transcriptional upregulation of TNF-R75 by proinflammatory cytokines interleukin 1beta, tumor necrosis factor-alpha, and basis fibroblast growth factor. (PubMed id 10090177)9 Alsalameh S....Kalden J.R. (1999)
    425. Selective induction of tumor necrosis factor receptor type II gene expression by tumor necrosis factor-alpha in C6 glioma cells. (PubMed id 9496711)9 Huang H....Tsang D. (1998)
    426. Differential expression, cytokine modulation, and specific functions of type-1 and type-2 tumor necrosis factor receptors in rat glia. (PubMed id 9143243)9 Dopp J.M....Merrill J.E. (1997)
    427. Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site. (PubMed id 9036990)9 Weiss T....Wajant H. (1997)
    428. Cytokine response of B lymphocytes from splenic lymphoma with villous lymphocytes: correlation with TNF-RII (p75) and CD11c expression. (PubMed id 8891726)9 Treton D....Richard Y. (1996)
    429. Serum p55 and p75 tumour necrosis factor receptors as markers of disease activity in juvenile chronic arthritis. (PubMed id 8733441)9 Gattorno M....Pistoia V. (1996)
    430. Regulation of NK cells through the 80-kDa TNFR (CD120b). (PubMed id 7543923)9 Mason A.T....Ortaldo J.R. (1995)
    431. p55 and p75 tumor necrosis factor receptor expression on human glioblastoma cells. (PubMed id 7566386)9 Kato T....Abe H. (1995)
    432. p55 and p75 tumor necrosis factor receptors are expressed and mediate common functions in synovial fibroblasts and other fibroblasts. (PubMed id 7880974)9 Butler D.M....Brennan F.M. (1994)
    433. The human cytomegalovirus 86-kilodalton immediate-early 2 protein: synthesis as a precursor polypeptide and interaction with a 75-kilodalton protein of probable viral origin. (PubMed id 8289376)9 Samaniego L.A....Spector D.J. (1994)
    434. Linkage mapping of the tumor necrosis factor receptor 2 (TNFR2) gene to 1p36.2 using the single-strand conformation polymorphism tec hnique. (PubMed id 7927340)9 Kaufman B.A....Brodeur G.M. (1994)
    435. Binding of G-CSF, GM-CSF, tumor necrosis factor-alpha, and gamma-interferon to cell surface receptors on human myeloid leukemia cells triggers rapid tyrosine and serine phosphorylation of a 75-Kd protein. (PubMed id 1688503)9 Evans J.P....Wickremasinghe R.G. (1990)
    436. Loss of SIMPL compromises TNF-alpha-dependent surviva l of hematopoietic progenitors. (PubMed id 19941935)9 Benson E.A....Harrington M.A. (2010)
    437. The role of IL-6, IL-10, TNF-alpha and its receptors TNFR1 and TNFR2 in the local regulatory system of normal and impaired human spe rmatogenesis. (PubMed id 19527232)9 BiaA8as M....Kurpisz M. (2009)
    438. Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration. (PubMed id 19435506)9 Millward-Sadler S.J....Hoyland J.A. (2009)
    439. TNF alpha acting on TNFR1 promotes breast cancer growth via p42/P44 MAPK, JNK, Akt and NF-kappa B-dependent pathways. (PubMed id 18061162)9 Rivas M.A....Schillaci R. (2008)
    440. Lovastatin induces neuroprotection through tumor necrosis factor receptor 2 signaling pathways. (PubMed id 18376053)9 Dolga A.M....Eisel U.L. (2008)
    441. [Relationship of apoptotic receptor expression in normal human peripheral blood lymphocytes to cell apoptosis] (PubMed id 17605860)9 Hu J....Gong J.P. (2007)
    442. Differential role of TNF receptors in cellular trafficking of intact TNF. (PubMed id 17762182)9 Pan W....Kastin A.J. (2007)
    443. Inhibition of tumor necrosis factor-alpha attenuates myocardial remodeling in rat cardiac allografts. (PubMed id 16678037)9 Sihvola R.K....LemstrAPm K.B. (2006)
    444. Neuroendocrine modulation induced by selective blockade of TNF-alpha in rheumatoid arthritis. (PubMed id 16855170)9 di Comite G....Sabbadini M.G. (2006)
    445. Role of tumor necrosis factor-alpha and its receptors in human benign breast lesions and tumors (in situ and infiltrative). (PubMed id 16984377)9 GarcA-a-TuA+A^n I....Royuela M. (2006)
    446. TNF-alpha induced c-IAP1/TRAF2 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitination. (PubMed id 15861135)9 Wu C.J....Ashwell J.D. (2005)
    447. The p55 TNF receptor mediates TNF inhibition of osteoblast differentiation independently of apoptosis. (PubMed id 15625085)9 Gilbert L.C....Nanes M.S. (2005)
    448. Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes. (PubMed id 12681357)9 Sawanobori M....Kitagawa M. (2003)
    449. The effects of deafferentation and exogenous NGF on neurotrophins and neurotrophin receptor mRNA expression in the adult superior cervical ganglion. (PubMed id 14597231)9 DeCouto S.A....Isaacson L.G. (2003)
    450. Pain-related differential expression of NGF, GDNF, IL-6, and their receptors in human vasculitic neuropathies. (PubMed id 14686749)9 Yamamoto M....Sobue G. (2003)
    451. Evidence that elastase is the TNF-R75 shedding enzyme in resting human polymorphonuclear leukocytes. (PubMed id 14572651)9 Gasparini C....Dri P. (2003)
    452. Cloning and characterization of cDNAs for two distinct tumor necrosis factor receptor superfamily genes from Japanese flounder Paralichthys olivaceus. (PubMed id 12631519)9 Park C.I....Aoki T. (2003)
    453. [Expression and distribution of NGF and p75 during rabbit tibial nerve repair induced by human hair keratin conduits] (PubMed id 13129723)9 Hu Q.L....Zou F. (2003)
    454. Tumor necrosis factor receptor-associated factor (TRAF) 2 and its role in TNF signaling. (PubMed id 11167129)9 Wajant H. and Scheurich P. (2001)
    455. Inflammatory cytokines and soluble receptors after coronary artery bypass grafting. (PubMed id 11563882)9 Wei M....Tarkka M. (2001)
    456. Collagen-induced arthritis in TNF receptor-1-deficient mice: TNF receptor-2 can modulate arthritis in the absence of TNF receptor-1. (PubMed id 11358427)9 Tada Y....Nagasawa K. (2001)
    457. Profiling of genes expressed in human monocytes and monocyte-derived dendritic cells using cDNA expression array. (PubMed id 11472367)9 Lapteva N....Tokunaga K. (2001)
    458. Tumor necrosis factor-alpha (TNF-alpha)-induced and interleukin-1 beta (IL-1 beta)-induced shedding of TNF receptors from gingival fibroblasts. (PubMed id 11152574)9 Ohe H....Murayama Y. (2000)
    459. Elevation of serum soluble tumour necrosis factor receptors in patients with polymyositis and dermatomyositis. (PubMed id 11055823)9 Shimizu T....Horie T. (2000)
    460. Tumor necrosis factor alpha 5'-flanking region, tumor necrosis factor receptor II, and HLA-DRB1 polymorphisms in Japanese patients with rheumatoid arthritis. (PubMed id 10765919)9 Shibue T....Tokunaga K. (2000)
    461. Further observations on the fetal inflammatory response syndrome: a potential homeostatic role for the soluble receptors of tumor necrosis factor alpha. (PubMed id 11084543)9 Romero R....Berry S.M. (2000)
    462. Neurotrophin signaling via Trks and p75. (PubMed id 10579918)9 Friedman W.J. and Greene L.A. (1999)
    463. IL-4 inhibits the migration of human Langerhans cells through the downregulation of TNF receptor II expression. (PubMed id 10504438)9 Takayama K....Nishioka K. (1999)
    464. Differential expression of tumor necrosis factor receptor subtypes on leukocytes in systemic inflammatory response syndrome. (PubMed id 10075056)9 HA1bl W....Bayer P.M. (1999)
    465. The anti-p75 antibody, MC192, and brain-derived neurotrophic factor inhibit nerve growth factor-dependent neurite growth from adult sensory neurons. (PubMed id 10430489)9 Kimpinski K....Mearow K. (1999)
    466. Expression pattern of tumour necrosis factor receptors in subcutaneous and omental human adipose tissue: role of obesity and non-insulin-dependent diabetes mellitus. (PubMed id 10457150)9 Hube F....Hauner H. (1999)
    467. Cooperation of both TNF receptors in inducing apoptosis: involvement of the TNF receptor-associated factor binding domain of the TNF receptor 75. (PubMed id 9647248)9 Declercq W....Vandenabeele P. (1998)
    468. Correlation of clinical and immunological parameters of metastatic renal cell carcinoma patients undergoing therapy with interleukin 2, interferon-alpha and retinoic acid. (PubMed id 9677439)9 ElsAosser-Beile U....Schultze-Seemann W. (1998)
    469. Soluble tumor necrosis factor receptor in serum of patients with arthritis. (PubMed id 9290265)9 Lee C.S....Wang P.C. (1997)
    470. 55- and 75-kilodalton tumor necrosis factor receptors mediate distinct actions in regard to human immunodeficiency virus type 1 replication in primary human macrophages. (PubMed id 9094699)9 Herbein G. and Gordon S. (1997)
    471. Tumor necrosis factor-alpha and tumor necrosis factor receptors in the failing human heart. (PubMed id 8640999)9 Torre-Amione G....Mann D.L. (1996)
    472. The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex. (PubMed id 8943045)9 Shu H.B....Goeddel D.V. (1996)
    473. TNF-receptors on human peritoneal mesothelial cells: regulation of receptor levels and shedding by IL-1 alpha and TNF alpha. (PubMed id 8807591)9 Douvdevani A....Chaimovitz C. (1996)
    474. Administration of recombinant human granulocyte-macrophage colony-stimulating factor after chemotherapy regulates the expression and secretion of monocyte tumor necrosis factor (TNF) and TNF receptors p55 and p75. (PubMed id 7492782)9 Williams M.A....Kelsey S.M. (1995)
    475. Neutrophil expression of tumour necrosis factor receptors (TNF-R) and of activation markers (CD11b, CD43, CD63) in rheumatoid arthritis. (PubMed id 7621589)9 Lopez S....Porteu F. (1995)
    476. Both tumor necrosis factor receptors, TNFR60 and TNFR80, are involved in signaling endothelial tissue factor expression by juxtacrine tumor necrosis factor alpha. (PubMed id 7544644)9 Schmid E.F....Pfizenmaier K. (1995)
    477. The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor. (PubMed id 8521496)9 Grell M....Scheurich P. (1995)
    478. A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes. (PubMed id 7869036)9 Crowe P.D....Ware C.F. (1995)
    479. Both TNF receptors are required for TNF-mediated indu ction of apoptosis in PC60 cells. (PubMed id 7876558)9 Vandenabeele P....Fiers W. (1995)
    480. Bifunctional effects of tumor necrosis factor alpha (TNF alpha) on the growth of mature and primitive human hematopoietic progenitor cells: involvement of p55 and p75 TNF receptors. (PubMed id 7514902)9 Rusten L.S....Jacobsen S.E. (1994)
    481. A human tumor necrosis factor (TNF) alpha mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon. (PubMed id 8145037)9 Van Zee K.J....StA1ber D. (1994)
    482. The TNF Receptors p55 and p75 Mediate Chemotaxis of PMN Induced by TNFalpha and a TNFalpha 36-62 Peptide. (PubMed id 18475579)9 Rekdal O....Osterud B. (1994)
    483. Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55. (PubMed id 8386742)9 Mackay F....Lesslauer W. (1993)
    484. p55 and p75 tumor necrosis factor receptors in patients with chronic lymphocytic leukemia. (PubMed id 1384790)9 Waage A....Espevik T. (1992)
    485. High concentrations of soluble tumor necrosis factor receptors in ascites. (PubMed id 1324217)9 Andus T....Scholmerich J. (1992)
    486. Enhanced expression of tumor necrosis factor receptor mRNA and protein in mononuclear cells isolated from rheumatoid arthritis synovial joints. (PubMed id 1320571)9 Brennan F.M....Feldmann M. (1992)
    487. Tumor necrosis factor receptor genes, TNFR1 and TNFR2, on human chromosomes 12 and 1. (PubMed id 1662415)9 Milatovich A....Francke U. (1991)
    488. Fluorescence correlation spectroscopy reveals topolog ical segregation of the two tumor necrosis factor membrane receptors. (PubMed id 20188063)9 Gerken M....Scheurich P. (2010)
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    490. Neuronal apoptosis is inhibited by cord blood stem ce lls after spinal cord injury. (PubMed id 19469692)9 Dasari V.R....Rao J.S. (2009)
    491. Blocking TNF in vitro with infliximab determines the inhibition of expansion and interferon gamma production of Vgamma9/Vdelta2 T lymphocytes from patients with active rheumatoid arthritis. A role in the susceptibility to tuberculosis? (PubMed id 19370184)9 Giardina A.R....Triolo G. (2009)
    492. Crystallization and preliminary X-ray analysis of the tumour necrosis factor alpha-tumour necrosis factor receptor type 2 complex. (PubMed id 19255488)9 Mukai Y....Tsutsumi Y. (2009)
    493. Expression of pro- and anti-inflammatory cytokines in relation to apoptotic genes in Egyptian liver disease patients associated with HCV-genotype-4. (PubMed id 19054267)9 Zekri A.R....Shaarawy S.M. (2009)
    494. Hyperinnervation in intestinal deep infiltrating endo metriosis. (PubMed id 19896597)9 Wang G....Fraser I.S. (2009)
    495. Nanoscale arrangement of apoptotic ligands reveals a demand for a minimal lateral distance for efficient death receptor activation. (PubMed id 19772290)9 Ranzinger J....Scheurich P. (2009)
    496. TNF-alpha as an autocrine mediator and its role in th e activation of Schwann cells. (PubMed id 18205044)9 Qin Y....Shen A. (2008)
    497. The influence of phytic acid on TNF-alpha and its receptors genes' expression in colon cancer Caco-2 cells. (PubMed id 18536177)9 Cholewa K....Weglarz L. (2008)
    498. Differential roles of p55 and p75 tumor necrosis factor receptors on stretch-induced pulmonary edema in mice. (PubMed id 17435079)9 Wilson M.R....Takata M. (2007)
    499. Tumor necrosis factor receptors (TNFRs) on T lymphocytes and soluble TNFRs in different clinical courses of sarcoidosis. (PubMed id 16889950)9 Kieszko R....Milanowski J. (2007)
    500. Plasma cytokine and soluble receptor signature predicts outcome of patients with classical Hodgkin's lymphoma: a study from the Groupe d'Etude des Lymphomes de l'Adulte. (PubMed id 17389336)9 Casasnovas R.O....Salles G. (2007)
    501. Effects of cytapheresis on tumor necrosis factor rece ptor and on expression of CD63 in myeloperoxidase--antineutrophil cytoplasmic a utoantibody-associated vasculitis. (PubMed id 17845393)9 Hasegawa M....Sugiyama S. (2007)
    502. Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome. (PubMed id 17697931)9 Kaimul A.M....Yodoi J. (2007)
    503. Predicting 5-fluorouracil chemosensitivity of liver metastases from colorectal cancer using primary tumor specimens: three-gene expression model predicts clinical response. (PubMed id 16477629)9 Matsuyama R....Shimada H. (2006)
    504. The biological differences between ovarian serous carcinoma and diffuse peritoneal malignant mesothelioma. (PubMed id 17044194)9 Davidson B....Reich R. (2006)
    505. Serum neopterin, tumor necrosis factor-alpha and soluble tumor necrosis factor receptor II (p75) levels and disease activity in Egyptian female patients with systemic lupus erythematosus. (PubMed id 15642275)9 Mahmoud R.A....Ahmed H.H. (2005)
    506. [The role of genetic polymorphisms within tumor necrosis factor promoter gene in non-Hodgkin's lymphomas] (PubMed id 16786763)9 Juszczynski P....Warzocha K. (2005)
    507. High expression of tumor necrosis factor alpha receptors in peripheral blood mononuclear cells of obese type 2 diabetic women. (PubMed id 15217754)9 Fogeda M....Richart C. (2004)
    508. Altered expression and activation of the nerve growth factor receptors TrkA and p75 provide the first evidence of tumor progression to effusion in breast carcinoma. (PubMed id 14997042)9 Davidson B....Nesland J.M. (2004)
    509. Expression of nerve growth factor (NGF), and its receptors trkA and p75 in ovaries of the cyclic golden hamster (Mesocricetus auratus) and the regulation of their production by luteinizing hormone. (PubMed id 15647611)9 Shi Z....Taya K. (2004)
    510. Electro-gene therapy of collagen-induced arthritis by using an expression plasmid for the soluble p75 tumor necrosis factor receptor-Fc fusion protein. (PubMed id 12858186)9 Kim J.M....Kim S. (2003)
    511. Circulating tumour necrosis factor alpha & soluble TNF receptors in patients with Guillain-Barre syndrome. (PubMed id 14609050)9 Radhakrishnan V.V....Nair M.D. (2003)
    512. Novel functional interactions between Trk kinase and p75 neurotrophin receptor in neuroblastoma cells. (PubMed id 12503079)9 Lachyankar M.B....Ross A.H. (2003)
    513. Development of androgen receptor and p75(NTR) mRNAs a nd peptides in the lumbar spinal cord of the gerbil. (PubMed id 12220702)9 Fraley G.S. and Ulibarri C. (2002)
    514. GDNF and NGF family members and receptors in human fetal and adult spinal cord and dorsal root ganglia. (PubMed id 11745618)9 Josephson A....Spenger C. (2001)
    515. Binding of nerve growth factor to its p75 receptor in stressed cells induces selective IkappaB-beta degradation and NF-kappaB nuclear translocation. (PubMed id 11677267)9 Cosgaya J.M. and Shooter E.M. (2001)
    516. Tumor necrosis factor receptor (TNFR) 1, but not TNFR2, mediates tumor necrosis factor-alpha-induced interleukin-6 and RANTES in human airway smooth muscle cells: role of p38 and p42/44 mitogen-activated protein kinases. (PubMed id 11562425)9 Amrani Y....Panettieri R.A. (2001)
    517. A menstrual cycle pattern for cytokine levels exists in HIV-positive women: implication for HIV vaginal and plasma shedding. (PubMed id 11504986)9 Al-Harthi L....Landay A. (2001)
    518. Modulation of TNF-alpha-induced apoptosis in corneal fibroblasts by transcription factor NF-kappaB. (PubMed id 10798647)9 Mohan R.R....Wilson S.E. (2000)
    519. Quantitative flow cytometry to measure the TNF-alpha and IL-2 system after heart transplantation. (PubMed id 11111998)9 van Riemsdijk I.C....Weimar W. (2000)
    520. Circulating concentrations of soluble interleukin 6 receptors gp80 and gp130 in chronic renal failure and effects of renal replacement therapy. (PubMed id 10575186)9 Frieling J.T....van Der Linden C.J. (1999)
    521. Increased TNF-alpha-induced apoptosis in lymphocytes from aged humans: changes in TNF-alpha receptor expression and activation of caspases. (PubMed id 9973490)9 Aggarwal S....Gupta S. (1999)
    522. Regulated commitment of TNF receptor signaling: a molecular switch for death or activation. (PubMed id 10626900)9 Pimentel-Muinos F.X. and Seed B. (1999)
    523. TNF-induced haptoglobin release from human neutrophils: pivotal role of the TNF p55 receptor. (PubMed id 10229868)9 Berkova N....Naccache P.H. (1999)
    524. Tumor necrosis factor-alpha mediates orthopedic implant osteolysis. (PubMed id 9916934)9 Merkel K.D....Teitelbaum S.L. (1999)
    525. Relationship between plasma leptin levels and the tumor necrosis factor-alpha system in obese subjects. (PubMed id 10340812)9 Corica F....Ceruso D. (1999)
    526. Suppression of growth and dissemination in human pre-B leukemia cells by tumor necrosis factor-alpha in scid mice. (PubMed id 10194127)9 Yoshida N....Miyazaki S. (1999)
    527. Prognostic significance of plasma markers of immune activation, HIV viral load and CD4 T-cell measurements. (PubMed id 9764776)9 Fahey J.L....Detels R. (1998)
    528. Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival. (PubMed id 9547236)9 Yoon S.O....Chao M.V. (1998)
    529. The role of type I and type II tumor necrosis factor (TNF) receptors in the ability of TNF-alpha to transduce a proliferative signal in the human megakaryoblastic leukemic cell line Mo7e. (PubMed id 9605769)9 Liu R.Y....Zuckerman K.S. (1998)
    530. Differential expression of a tumor necrosis factor receptor-related transcript in gestational trophoblastic diseases in women. (PubMed id 9716562)9 Dumur C.I.... Patrito L.C. (1998)
    531. Maternal serum levels of interleukin-6 and clinical characteristics of normal delivery at term. (PubMed id 9033245)9 Arntzen K.J....Austgulen R. (1997)
    532. Human neoplastic Schwann cells: changes in the expression of neurotrophins and their low-affinity receptor p75. (PubMed id 9364463)9 Bonetti B....Moretto G. (1997)
    533. Immunocytochemical expression of human muscle cell p75 neurotrophin receptor is down-regulated by cyclic adenosine 3',5'-monophosphate. (PubMed id 9364502)9 Baron P....Scarlato G. (1997)
    534. [TNF] (PubMed id 9309146)9 Yamauchi N. and Niitsu Y. (1997)
    535. Interleukin-4, interleukin-10, and soluble tumor necrosis factor receptors in cord blood. (PubMed id 9127126)9 Hata T....Inada K. (1997)
    536. In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis. (PubMed id 9394812)9 KA1sters S....Grell M. (1997)
    537. Differential regulation of the p80 tumor necrosis factor receptor in human obesity and insulin resistance. (PubMed id 9032102)9 Hotamisligil G.S....Spiegelman B.M. (1997)
    538. Tumour necrosis factor alpha and its soluble receptors parallel clinical disease and autoimmune activity in systemic lupus erythematosus. (PubMed id 8948291)9 Studnicka-Benke A....Smolen J.S. (1996)
    539. Tumor necrosis factor (TNF) stimulates the production of nerve growth factor in fibroblasts via the 55-kDa type 1 TNF receptor. (PubMed id 8635583)9 Hattori A....Kohno M. (1996)
    540. Structural and biological features of the TNF receptor and TNF ligand superfamilies: interactive signals in the pathobiology of Hodgkin's disease. (PubMed id 8836404)9 Gruss H.J....Herrmann F. (1996)
    541. TNF-mediated cytotoxicity and resistance in human prostate cancer cell lines. (PubMed id 8899002)9 Nakajima Y....Ferreri N.R. (1996)
    542. Tumor necrosis factor soluble receptor 75: the principal receptor form released by human alveolar macrophages and monocytes in the presence of interferon gamma. (PubMed id 8845179)9 Galve-de Rochemonteix B....Dayer J.M. (1996)
    543. Point mutations in the conserved box 1 region inactivate the human granulocyte colony-stimulating factor receptor for growth signal transduction and tyrosine phosphorylation of p75c-rel. (PubMed id 7538818)9 Avalos B.R....Mehta V.B. (1995)
    544. Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour necrosis factor (TNF) receptor is mediated by endogenous murine TNF. (PubMed id 7578985)9 Vercammen D....Fiers W. (1995)
    545. Soluble tumour necrosis factor receptors p55 and p75 in the urine monitor disease activity and the efficacy of treatment of inflammatory bowel disease. (PubMed id 7557578)9 Hadziselimovic F....Gallati H. (1995)
    546. TNF receptor signal transduction. Ligand-dependent stimulation of a serine protein kinase activity associated with (CD120a) TNFR60. (PubMed id 8089485)9 VanArsdale T.L. and Ware C.F. (1994)
    547. Elevated tumour necrosis factor-alpha (TNF-alpha) biological activity in psoriatic skin lesions. (PubMed id 8149659)9 Ettehadi P....Camp R.D. (1994)
    548. Modulation of the transcripts for tumor necrosis factor-alpha and its receptors in vivo. (PubMed id 8125144)9 de Kossodo S....Grau G.E. (1994)
    549. Mechanisms involved in the processing of the p55 and the p75 tumor necrosis factor (TNF) receptors to soluble receptor forms. (PubMed id 7948429)9 BjAPrnberg F....Gullberg U. (1994)
    550. Relationship between soluble tumor necrosis factor (TNF) receptors and TNF alpha during immunotherapy with interleukin-2 and/or interferon alpha. (PubMed id 8306366)9 Landmann R....Ludwig C. (1994)
    551. Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity. (PubMed id 7519237)9 Bigda J....Wallach D. (1994)
    552. Analysis of cytokine receptor messenger RNA expression in human glioblastoma cells and normal astrocytes by reverse-transcription polymerase chain reaction. (PubMed id 7514661)9 Tada Tribolet N. (1994)
    553. Tumor necrosis factor, its receptors and the connection with interleukin 1 and interleukin 6. (PubMed id 8392490)9 Brouckaert P....Fiers W. (1993)
    554. Antiviral activity of tumor necrosis factor is signaled through the 55-kDa type I TNF receptor [corrected] (PubMed id 1331233)9 Wong G.H....Goeddel D.V. (1992)
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    556. Pericardial fat volume correlates with inflammatory m arkers: the Framingham Heart Study. (PubMed id 19875999)9 Tadros T.M....Benjamin E.J. (2010)
    557. Different responsiveness of endothelial cells to vasc ular endothelial growth factor and basic fibroblast growth factor added to cult ure media under gravity and simulated microgravity. (PubMed id 20001221)9 Grimm D....Baatout S. (2010)
    558. Differential roles of Trk and p75 neurotrophin recept ors in tumorigenesis and chemoresistance ex vivo and in vivo. (PubMed id 19701634)9 Bassili M....Saragovi H.U. (2010)
    559. [Expressions of neurotrophic factors and their recept ors in prostate cancer] (PubMed id 20369695)9 Liu M....Chen Y. (2010)
    560. Creation of an improved mutant TNF with TNFR1-selecti vity and antagonistic activity by phage display technology. (PubMed id 20225650)9 Nomura T....Tsutsumi Y. (2010)
    561. Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss? (PubMed id 20403960)9 Fontana A....Bassetti C.L. (2010)
    562. Dual function of cysteine rich domain (CRD) 1 of TNF receptor type 1: conformational stabilization of CRD2 and control of receptor r esponsiveness. (PubMed id 19879354)9 BranschAodel M....Scheurich P. (2010)
    563. Human lactoferrin activates NF-kappaB through the Tol l-like receptor 4 pathway while it interferes with the lipopolysaccharide-stimu lated TLR4 signaling. (PubMed id 20345905)9 Ando K....Hayakawa M. (2010)
    564. Multiplex genotyping of 1107 SNPs from 232 candidate genes identified an association between IL1A polymorphism and breast cancer ris k. (PubMed id 20127018)9 Han W....Noh D.Y. (2010)
    565. Lupus serum IgG induces skin inflammation through the TNFR1 signaling pathway. (PubMed id 20483718)9 Deng G.M....Tsokos G.C. (2010)
    566. CD133 identifies a human bone marrow stem/progenitor cell sub-population with a repertoire of secreted factors that protect against stroke. (PubMed id 19690521)9 Bakondi B....Spees J.L. (2009)
    567. The relation of genetic and environmental factors to systemic inflammatory biomarker concentrations. (PubMed id 20031590)9 Schnabel R.B....Benjamin E.J. (2009)
    568. Circulating proinflammatory cytokines and N-terminal pro-brain natriuretic peptide significantly decrease with recovery of left ventricular function in patients with dilated cardiomyopathy. (PubMed id 19107325)9 Ahmad S....Khullar M. (2009)
    569. Rheumatoid arthritis-associated gene-gene interaction network for rheumatoid arthritis candidate genes. (PubMed id 20018070)9 Huang C.H....Zheng T. (2009)
    570. Expression and regulation of tumor necrosis factor (TNF) and TNF-receptor family members in the macaque corpus luteum during the menstrual cycle. (PubMed id 18932199)9 Peluffo M.C....Stouffer R.L. (2009)
    571. Aggressive periodontitis and chronic arthritis: blood mononuclear cell gene expression and plasma protein levels of cytokines and cytokine inhibitors. (PubMed id 19186969)9 SA...Holmstrup P. (2009)
    572. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced chemokine release in both TRAIL-resistant and TRAIL-sensitive cells via nuclear factor kappa B. (PubMed id 19120450)9 Tang W....Zheng D. (2009)
    573. Cross-sectional relations of multiple inflammatory biomarkers to peripheral arterial disease: The Framingham Offspring Study. (PubMed id 18701106)9 Murabito J.M....Benjamin E.J. (2009)
    574. Inflammatory biomarkers in heart failure revisited: m uch more than innocent bystanders. (PubMed id 19631179)9 von Haehling S....Anker S.D. (2009)
    575. Relation of multiple inflammatory biomarkers to incid ent atrial fibrillation. (PubMed id 19576326)9 Schnabel R.B....Benjamin E.J. (2009)
    576. Characterization of the HDAC1 complex that regulates the sensitivity of cancer cells to oxidative stress. (PubMed id 19351825)9 Kato T....Takahashi M. (2009)
    577. Human tumour necrosis factor: physiological and pathological roles in placenta and endometrium. (PubMed id 19027157)9 Haider S. and KnAPfler M. (2009)
    578. Body iron stores and glucose intolerance in premenopa usal women: role of hyperandrogenism, insulin resistance, and genomic variants related to inflammation, oxidative stress, and iron metabolism. (PubMed id 19401444)9 MartA-nez-GarcA-a M.A....Escobar-Morreale H.F. (2009)
    579. Soluble TNFR II/IgG1 Fc fusion protein treatment in t he LPS-mediated septic shock of rats. (PubMed id 18848768)9 Guo Z....Xu Z. (2009)
    580. TNF receptors differentially signal and are different ially expressed and regulated in the human heart. (PubMed id 19788501)9 Al-Lamki R.S....Bradley J.R. (2009)
    581. Reproducibility of serum cytokines and growth factors. (PubMed id 19058974)9 Gu Y....Arslan A.A. (2009)
    582. TNF-alpha as a therapeutic target in inflammatory dis eases, ischemia-reperfusion injury and trauma. (PubMed id 19689289)9 Esposito E. and Cuzzocrea S. (2009)
    583. Leukemic phase of follicular lymphoma after treatment with etanercept in a patient with psoriasis. (PubMed id 19222252)9 Ganguly S. (2009)
    584. [Induction of apoptosis by tumor necrosis factor receptors 2 transgene in human laryngeal squamous cacinoma in nude mice animal model] (PubMed id 19452731)9 Li H....Lu X. (2009)
    585. Tyrosine kinase nerve growth factor receptor switches from prosurvival to proapoptotic activity via Abeta-mediated phosphorylation. (PubMed id 19549834)9 Matrone C....Calissano P. (2009)
    586. Rich innervation of deep infiltrating endometriosis. (PubMed id 19151028)9 Wang G....Fraser I.S. (2009)
    587. Infliximab and the TNF-alpha system. (PubMed id 19136378)9 Ebert E.C. (2009)
    588. Death receptor expression is associated with poor response to chemotherapy and shorter survival in metastatic ovarian carcinoma. (PubMed id 17985388)9 Dong H.P....Davidson B. (2008)
    589. p75 and TrkC neurotrophin receptors demonstrate a different immunoreactivity profile in comparison to TrkA and TrkB receptors in human normal pituitary gland and adenomas. (PubMed id 18319596)9 Assimakopoulou M....Varakis J. (2008)
    590. Increased arterial stiffness and indication of endothelial dysfunction in long-standing rheumatoid arthritis. (PubMed id 18189187)9 WAYllberg-Jonsson S....RantapAoAo-Dahlqvist S. (2008)
    591. BDNF in RA: downregulated in plasma following anti-TNF treatment but no correlation with inflammatory parameters. (PubMed id 18484150)9 Grimsholm O....Forsgren S. (2008)
    592. TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor. (PubMed id 18313334)9 Gardam S....Brink R. (2008)
    593. Growth inhibition and radiosensitization of glioblastoma and lung cancer cells by small interfering RNA silencing of tumor necrosis factor receptor-associated factor 2. (PubMed id 18794145)9 Zheng M....Sun Y. (2008)
    594. Non-response to infliximab may be due to innate neutr alizing anti-tumour necrosis factor-alpha antibodies. (PubMed id 18826498)9 Ebert E.C....Rezac C. (2008)
    595. TL1A both promotes and protects from renal inflammation and injury. (PubMed id 18287561)9 Al-Lamki R.S....Bradley J.R. (2008)
    596. Human idiopathic epiretinal membranes express NGF and NGF receptors. (PubMed id 18398367)9 Minchiotti S....Bonini S. (2008)
    597. Neurotrophin receptor expression in human primary retinoblastomas and retinoblastoma cell lines. (PubMed id 17973327)9 Stephan H....Eggert A. (2008)
    598. Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection. (PubMed id 18426996)9 Schnabel R....Benjamin E.J. (2008)
    599. TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease. (PubMed id 18925972)9 McCoy M.K. and Tansey M.G. (2008)
    600. Associations of resistin with inflammatory and fibrinolytic markers, insulin resistance, and metabolic syndrome in middle-aged and older Chinese. (PubMed id 18753313)9 Qi Q....Lin X. (2008)
    601. Adenoviral gene transfer of the endogenous inhibitor IkappaBalpha into human osteoarthritis synovial fibroblasts demonstrates that several matrix metalloproteinases and aggrecanases are nuclear factor-kappaB-dependent. (PubMed id 17295438)9 Bondeson J....Caterson B. (2007)
    602. A dual role for the API2 moiety in API2-MALT1-dependent NF-kappaB activation: heterotypic oligomerization and TRAF2 recruitment. (PubMed id 17334391)9 Lucas P.C....McAllister-Lucas L.M. (2007)
    603. Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children. (PubMed id 17997848)9 Armah H.B....Stiles J.K. (2007)
    604. Microparticles of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1. (PubMed id 17872973)9 Canault M....Nalbone G. (2007)
    605. Tumor necrosis factor blockade in the management of c hildren with orphan diseases. (PubMed id 17219021)9 Brik R....Berkovitz D. (2007)
    606. Correlates for disease progression and prognosis during concurrent HIV/TB infection. (PubMed id 17446108)9 Djoba Siawaya J.F....Walzl G. (2007)
    607. [Expression peculiarities of EGR1, neurotrophins and their receptor genes in human lung cancer and in normal lung tissue] (PubMed id 17600921)9 Dergunoa L.V....Limborskaia S.A. (2007)
    608. Inflammatory biomarkers are associated with total brain volume: the Framingham Heart Study. (PubMed id 17389308)9 Jefferson A.L....DeCarli C. (2007)
    609. Construction and purification of the murine p75-murine IgG1 fusion protein. (PubMed id 17502870)9 Kim H.Y....Kohno T. (2007)
    610. Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study. (PubMed id 17709633)9 Pou K.M....Fox C.S. (2007)
    611. Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1. (PubMed id 17724081)9 Fujino G....Ichijo H. (2007)
    612. TrkC: a new predictive marker in breast cancer? (PubMed id 17882651)9 Blasco-Gutierrez M.J....Garcia-Atares N. (2007)
    613. The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas. (PubMed id 16862449)9 Perez-Pinera P....Vega J.A. (2007)
    614. Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling. (PubMed id 17314283)9 Henn I.H....Winklhofer K.F. (2007)
    615. Proinflammatory cytokines stimulate the expression of nerve growth factor by human intervertebral disc cells. (PubMed id 17413467)9 Abe Y....Masuda K. (2007)
    616. TRAF1 and its biological functions. (PubMed id 17633014)9 Lee S.Y. and Choi Y. (2007)
    617. Predominant activation of MAP kinases and pro-destructive/pro-inflammatory features by TNF alpha in early-passage synovial fibroblasts via TNF receptor-1: failure of p38 inhibition to suppress matrix metalloproteinase-1 in rheumatoid arthritis. (PubMed id 17223661)9 Kunisch E....Kinne R.W. (2007)
    618. Systemic inflammatory mediators and bone homeostasis in intestinal failure. (PubMed id 17308255)9 Compher C....Hise M. (2007)
    619. Retinoic acid enhances Erk phosphorylation in the chick retina. (PubMed id 17881122)9 Kampmann E. and Mey J. (2007)
    620. [Autoimmune aspects of treatment with TNF-alpha inhibitors] (PubMed id 17786135)9 Kolarz B....Majdan M. (2007)
    621. Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system. (PubMed id 17172268)9 Berndt C....Holmgren A. (2007)
    622. Different TNFalpha expression elicited by glucose in monocytes from type 2 diabetes mellitus patients. (PubMed id 17244513)9 Chacon M.R....Garcia-Espana A. (2007)
    623. Novel action of n-3 polyunsaturated fatty acids: inhibition of arachidonic acid-induced increase in tumor necrosis factor receptor expression on neutrophils and a role for proteases. (PubMed id 17328054)9 Moghaddami N....Ferrante A. (2007)
    624. Association of classical and related inflammatory markers with high-sensitivity C-reactive protein in healthy individuals: results from the Stanislas cohort. (PubMed id 17727316)9 Berrahmoune H....Visvikis-Siest S. (2007)
    625. Characterization of porcine tumor necrosis factor rec eptor 2: implications for xenotransplantation. (PubMed id 17889214)9 Costa C....Fodor W.L. (2007)
    626. Physiological roles and mechanisms of signaling by TRAF2 and TRAF5. (PubMed id 17633015)9 Au P.Y. and Yeh W.C. (2007)
    627. The role of TNF-alpha and its receptors in the production of NGF and GDNF by astrocytes. (PubMed id 16956589)9 Kuno R....Suzumura A. (2006)
    628. Activation of toll-like receptor-9 induces matrix metalloproteinase-9 expression through Akt and tumor necrosis factor-alpha signaling. (PubMed id 16870179)9 Lim E.J....Baek S.H. (2006)
    629. Human glutathione S-transferase P1-1 interacts with TRAF2 and regulates TRAF2-ASK1 signals. (PubMed id 16636664)9 Wu Y....Yin Z. (2006)
    630. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation. (PubMed id 16219905)9 Aggarwal S....Aggarwal B.B. (2006)
    631. Etanercept decreases tumor necrosis factor-alpha acti vity in chronic wound fluid. (PubMed id 16939569)9 Cowin A.J....Belford D.A. (2006)
    632. Expression of TWEAK and its receptor Fn14 in human subcutaneous adipose tissue. Relationship with other inflammatory cytokines in obesity. (PubMed id 16503147)9 Chacon M.R....Vendrell J. (2006)
    633. Expression of TNF-alpha and related signaling molecules in the peripheral blood mononuclear cells of rheumatoid arthritis patients. (PubMed id 16951485)9 Raghav S.K....Das H.R. (2006)
    634. Increased levels of soluble TNF-alpha receptors and cellular adhesion molecules in patients undergoing bioincompatible hemodialysis. (PubMed id 16988495)9 Rysz J....Baj Z. (2006)
    635. Expression of thioredoxin and thioredoxin-binding protein-2 in the liver of patients with chronic hepatitis C as a predictor of response to interferon therapy. (PubMed id 16685406)9 Hamano K....Kasuga M. (2006)
    636. Soluble human p55 and p75 tumor necrosis factor receptors reverse spontaneous arthritis in transgenic mice expressing transmembrane tumor necrosis factor alpha. (PubMed id 16947419)9 Edwards C.K....Dinarello C.A. (2006)
    637. Thioredoxin in cancer--role of histone deacetylase inhibitors. (PubMed id 17095247)9 Marks P.A. (2006)
    638. TNFR-Fc fusion protein expressed by in vivo electroporation improves survival rates and myocardial injury in coxsackievirus induced murine myocarditis. (PubMed id 16631119)9 Kim J.M....Jeon E.S. (2006)
    639. Use of etanercept in human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) patients. (PubMed id 16796629)9 Ting P.T. and Koo J.Y. (2006)
    640. Extracellular thioredoxin and thioredoxin-binding protein 2 in control of cancer. (PubMed id 17095246)9 Nakamura H....Yodoi J. (2006)
    641. [Changes in gene expression in the course of proliferative processes in the parathyroid gland] (PubMed id 16888677)9 Szende B....Perner F. (2006)
    642. Allogeneic activation is attenuated in a model of mouse lung perfused with magnesium-deficient blood. (PubMed id 17138054)9 Sabbagh F....German-Fattal M. (2006)
    643. Thioredoxin-binding protein-2-like inducible membrane protein is a novel vitamin D3 and peroxisome proliferator-activated receptor (PPAR)gamma ligand target protein that regulates PPARgamma signaling. (PubMed id 16269462)9 Oka S....Yodoi J. (2006)
    644. TNF and TNF receptor expression and insulin sensitivity in human omental and subcutaneous adipose tissue--influence of BMI and adipose distribution. (PubMed id 16784178)9 Good M....Prins J.B. (2006)
    645. Preliminary investigation of gene expression profiles in peripheral blood lymphocytes in schizophrenia. (PubMed id 16414245)9 Bowden N.A....Tooney P.A. (2006)
    646. Trophic factors in cerebrospinal fluid and spinal cord of patients with tropical spastic paraparesis, HIV, and Creutzfeldt-Jakob disease. (PubMed id 16545011)9 Albrecht D....Valenzuela M.A. (2006)
    647. Relationship between plasma concentrations of cytokin es, ratio of CD4 and CD8, lymphocyte proliferative responses, and depressive an d anxiety state in bulimia nervosa. (PubMed id 16380316)9 Nagata T....Kiriike N. (2006)
    648. Successful antidepressant therapy restores the disturbed interplay between TNF-alpha system and HPA axis. (PubMed id 16989778)9 Himmerich H....Ising M. (2006)
    649. Interferon induces NF-kappa B-inducing kinase/tumor necrosis factor receptor-associated factor-dependent NF-kappa B activation to promote cell survival. (PubMed id 16009713)9 Yang C.H....Pfeffer L.M. (2005)
    650. Pneumococcal meningitis and etanercept--chance or ass ociation? (PubMed id 16038750)9 Killingley B....Pasvol G. (2005)
    651. Apoptotic markers on lymphocytes and monocytes are unchanged during single hemodialysis sessions using either regenerated cellulose or polysulfone membranes. (PubMed id 16175944)9 Wu C.C....Lin Y.F. (2005)
    652. TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs. (PubMed id 15708970)9 Hauer J....Engelmann H. (2005)
    653. Tumor necrosis factor alpha promotes invasiveness of cholangiocarcinoma cells via its receptor, TNFR2. (PubMed id 15723721)9 Tanimura Y....Hamaguchi M. (2005)
    654. A shift to a peripheral Th2-type cytokine pattern during the carcinogenesis of cervical cancer becomes manifest in CIN III lesions. (PubMed id 16189158)9 Bais A.G....Helmerhorst T.J. (2005)
    655. Relationship between exercise intolerance and levels of neurohormonal factors and proinflammatory cytokines in patients with stable chronic heart failure. (PubMed id 16394601)9 Itoh K....Miyake F. (2005)
    656. Evidence of a mechanism by which etanercept increased TNF-alpha in multiple myeloma: new insights into the biology of TNF-alpha giving new treatment opportunities--the role of bupropion. (PubMed id 15964626)9 Kast R.E. (2005)
    657. Exercise training in chronic heart failure: effects on pro-inflammatory markers. (PubMed id 15701465)9 Niebauer J....Coats A.J. (2005)
    658. Cytokines, cytokine antagonists and soluble adhesion molecules in patients with ocular BehAset's disease treated with human recombinant interferon-alpha2a. Results of an open study and review of the literature. (PubMed id 16273760)9 KAPtter I....StA1biger N. (2005)
    659. Protection of human cerebral neurons from neurodegenerative insults by gene delivery of soluble tumor necrosis factor p75 receptor. (PubMed id 15827736)9 Williams M.A....Drachman D.B. (2005)
    660. Tumor necrosis factor-alpha inhibits seizures in mice via p75 receptors. (PubMed id 15852477)9 Balosso S....Vezzani A. (2005)
    661. Amino-terminal TACE prodomain attenuates TNFR2 cleavage independently of the cysteine switch. (PubMed id 15749738)9 Buckley C.A....Levine S.J. (2005)
    662. Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival. (PubMed id 16049186)9 Kuwako K....Yoshikawa K. (2005)
    663. Anti-TNF-alpha therapy in ankylosing spondylitis. (PubMed id 15212600)9 Wendling D. and Toussirot E. (2004)
    664. Etanercept for the treatment of psoriasis and psoriat ic arthritis. (PubMed id 15379775)9 Gottlieb A.B. (2004)
    665. Upregulation and colocalization of p75 and Nav1.8 in Purkinje neurons in experimental autoimmune encephalomyelitis. (PubMed id 15464262)9 Damarjian T.G....Waxman S.G. (2004)
    666. Marek's disease is a natural model for lymphomas overexpressing Hodgkin's disease antigen (CD30). (PubMed id 15356338)9 Burgess S.C....Davison T.F. (2004)
    667. Circulating cytokines in primary SjAPgren's syndrome determined by a multiplex cytokine array system. (PubMed id 15182255)9 Szodoray P....Jonsson R. (2004)
    668. A pilot study of the safety and tolerability of etanercept in patients with alcoholic hepatitis. (PubMed id 15046213)9 Menon K.V....Shah V. (2004)
    669. Nerve growth factor-induced protein kinase C stimulation contributes to TrkA-dependent inhibition of p75 neurotrophin receptor sphingolipid signaling. (PubMed id 15264216)9 Plo I....Laurent G. (2004)
    670. Correlation of serum soluble TNF-alpha receptors I and II levels with disease activity in patients with ulcerative colitis. (PubMed id 15307873)9 Hanai H....Saniabadi A. (2004)
    671. Lipodystrophy in patients with HIV-1 infection: effect of stopping protease inhibitors on TNF-alpha and TNF-receptor levels, and on metabolic parameters. (PubMed id 15651746)9 Maher B....Pirmohamed M. (2004)
    672. Lowered tumor necrosis factor receptors, but not increased insulin sensitivity, with infliximab. (PubMed id 15090644)9 Di Rocco P....Mingrone G. (2004)
    673. Serum tumour necrosis factor-alpha and soluble tumour necrosis factor receptors levels in patients with Guillain-Barre syndrome. (PubMed id 14653854)9 Radhakrishnan V.V....Nair M.D. (2004)
    674. Overexpression of tumor necrosis factor (TNF)alpha and TNFalpha receptor I in human viral myocarditis: clinicopathologic correlations. (PubMed id 15218506)9 Calabrese F....Thiene G. (2004)
    675. Inflammatory cytokines in acute renal failure. (PubMed id 15461705)9 Ramesh G. and Reeves W.B. (2004)
    676. A low serum level of soluble tumor necrosis factor receptor p55 predicts response to thalidomide in advanced multiple myeloma. (PubMed id 15136218)9 Brenne A.T....Waage A. (2004)
    677. P75 tumor necrosis factor-receptor shedding occurs as a protective host response during African trypanosomiasis. (PubMed id 14745712)9 Magez S....De Baetselier P. (2004)
    678. Etanercept: in ankylosing spondylitis. (PubMed id 15161337)9 McCormack P.L. and Wellington K. (2004)
    679. Lymphotoxin and LIGHT signaling pathways and target genes. (PubMed id 15546385)9 Schneider K....Ware C.F. (2004)
    680. Correlations among neural cell adhesion molecule, nerve growth factor, and its receptors, TrkA, TrkB, TrkC, and p75, in perineural invasion by basal cell and cutaneous squamous cell carcinomas. (PubMed id 15209791)9 Chen-Tsai C.P....Wagner R.F. (2004)
    681. Cardiomyocyte death in patients with end-stage heart failure before and after support with a left ventricular assist device: low incidence of apoptosis despite ubiquitous mediators. (PubMed id 12957613)9 de Jonge Weger R.A. (2003)
    682. Unique effect of arachidonic acid on human neutrophil TNF receptor expression: up-regulation involving protein kinase C, extracellular signal-regulated kinase, and phospholipase A2. (PubMed id 12928414)9 Moghaddami N....Ferrante A. (2003)
    683. Innate immune system is implicated in recurrent aphthous ulcer pathogenesis. (PubMed id 12901729)9 Lewkowicz N....TchA^rzewski H. (2003)
    684. Synergy between all-trans retinoic acid and tumor nec rosis factor pathways in acute leukemia cells. (PubMed id 12586626)9 Witcher M....Miller W.H. (2003)
    685. Meningeal cells enhance limited CNS remyelination by transplanted olfactory ensheathing cells. (PubMed id 12566281)9 Lakatos A....Franklin R.J. (2003)
    686. Tumor necrosis factor-induced nuclear factor kappaB activation is impaired in focal adhesion kinase-deficient fibroblasts. (PubMed id 12748169)9 Funakoshi-Tago M....Kasahara T. (2003)
    687. Comparative analysis of genes regulated by PML/RAR alpha and PLZF/RAR alpha in response to retinoic acid using oligonucleotide arrays. (PubMed id 12893766)9 Park D.J....Koeffler H.P. (2003)
    688. Vgamma9/Vdelta2 T lymphocytes in Italian patients wit h BehAset's disease: evidence for expansion, and tumour necrosis factor receptor II and interleukin-12 receptor beta1 expression in active disease. (PubMed id 12932289)9 Triolo G....Licata G. (2003)
    689. Influence of leptin and the TNF system on insulin resistance in pregnancy and their effect on anthropometric parameters of newborns. (PubMed id 12752073)9 Melczer Z....Cseh K. (2003)
    690. Modulation by caspases of tumor necrosis factor-stimulated c-Jun N-terminal kinase activation but not nuclear factor-kappaB signaling. (PubMed id 12473383)9 Littlejohn A.F....MacEwan D.J. (2003)
    691. In situ localization of TNFalpha/beta, TACE and TNF receptors TNF-R1 and TNF-R2 in control and LPS-treated lung tissue. (PubMed id 12849708)9 Ermert M....Ermert L. (2003)
    692. Genetic determinants of susceptibility to osteoporosis. (PubMed id 12699293)9 Albagha O.M. and Ralston S.H. (2003)
    693. Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and TNF-alpha promote the NF-kappaB-dependent maturation of normal and leukemic myeloid cells. (PubMed id 12885939)9 Secchiero P....Zauli G. (2003)
    694. Cytokine and cytokine receptor serum levels in adult bone sarcoma patients: correlations with local tumor extent and prognosis. (PubMed id 14598359)9 Rutkowski P....Steffen J. (2003)
    695. The role of nuclear factor kappaB in tumor necrosis factor-regulated transcription of the human mu-opioid receptor gene. (PubMed id 14500744)9 Kraus J....HAPllt V. (2003)
    696. ErbB-2/HER-2 protein expression, serum tumour necrosis factor-alpha (TFM-alpha) and soluble tumour necrosis factor receptor-2 (TNFR-2) concentrations in human carcinoma of the uterine cervix. (PubMed id 12701963)9 Melczer Z....Cseh K. (2003)
    697. Apoptotic response to 5-fluorouracil treatment is mediated by reduced polyamines, non-autocrine Fas ligand and induced tumor necrosis factor receptor 2. (PubMed id 14614330)9 Zhang W....Hamilton S.R. (2003)
    698. Pilot study of recombinant human soluble tumor necros is factor (TNF) receptor (p75) fusion protein (TNFR:Fc; Enbrel) in patients wit h refractory multiple myeloma: increase in plasma TNF alpha levels during treat ment. (PubMed id 12620287)9 Tsimberidou A.M....Giles F.J. (2003)
    699. Activation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein. (PubMed id 12915550)9 Brinkmann M.M....Schulz T.F. (2003)
    700. Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis. (PubMed id 12441346)9 Vanden Berghe T....Vandenabeele P. (2003)
    701. Preferential induction of prodestructive matrix metalloproteinase-1 and proinflammatory interleukin 6 and prostaglandin E2 in rheumatoid arthritis synovial fibroblasts via tumor necrosis factor receptor-55. (PubMed id 12913922)9 Alsalameh S....Kinne R.W. (2003)
    702. Effect of acute hyperglycaemia on selected plasma and urinary cytokine antagonists in Type 1 diabetes mellitus. (PubMed id 12679866)9 PelikA!novA! T....Jirsa M. (2003)
    703. NGF rescues human B lymphocytes from anti-IgM induced apoptosis by activation of PKCzeta. (PubMed id 11754354)9 Kronfeld I....Brodie C. (2002)
    704. Neurotropins and their receptors are expressed in the human fetal ovary. (PubMed id 11836338)9 Anderson R.A....Spears N. (2002)
    705. Psoriatic arthritis: the role of TNF inhibition and the effect of its inhibition with etanercept. (PubMed id 12463460)9 Mease P. (2002)
    706. Chloroquine decreases cell-surface expression of tumo ur necrosis factor receptors in human histiocytic U-937 cells. (PubMed id 11849318)9 Jeong J.Y....Jue D.M. (2002)
    707. Serum cholesterol levels in neutropenic patients with fever. (PubMed id 12005222)9 Fraunberger P....Seidel D. (2002)
    708. Oxidative stress modulates tyrosine kinase receptor A and p75 receptor (low-affinity nerve growth factor receptor) expression in SHSY5Y neuroblastoma cells. (PubMed id 12028822)9 Olivieri G....Savaskan E. (2002)
    709. Pharmacogenomics of response to anti-tumor necrosis factor therapy in patients with Crohn's disease. (PubMed id 12421092)9 Shetty A. and Forbes A. (2002)
    710. Testosterone and diurnal rhythmicity of leptin, TNF-alpha and TNF-II receptor in insulin-resistant myotonic dystrophy patients. (PubMed id 12355336)9 Johansson A....Olsson T. (2002)
    711. Does NGF binding to p75 and trkA receptors activate i ndependent signalling pathways to sensitize nociceptors? (PubMed id 12381805)9 Mendell L.M. (2002)
    712. Signaling molecules of the NF-kappa B pathway shuttle constitutively between cytoplasm and nucleus. (PubMed id 11801607)9 Birbach A....Schmid J.A. (2002)
    713. Resection of pancreatic cancer normalizes the preoperative increase of tumor necrosis factor alpha gene expression. (PubMed id 12378118)9 Ariapart P....Lundkvist I. (2002)
    714. Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor alpha. (PubMed id 11986408)9 Gorman J.D....Davis J.C. (2002)
    715. Emerging role of anti-tumor necrosis factor therapy in rheumatic diseases. (PubMed id 12110156)9 Kalden J.R. (2002)
    716. The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin. (PubMed id 12189205)9 Butler L.M....Richon V.M. (2002)
    717. [cDNA array approach to cytokine expression profile of aseptic loosened hip arthroplasty] (PubMed id 12376864)9 Gentzsch C....Delling G. (2002)
    718. TNF-alpha receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurones. (PubMed id 11750919)9 Pollock J....Scott R.H. (2002)
    719. Variations in immune response genes and their associations with multifactorial immune disorders. (PubMed id 12493014)9 Tsuchiya N....Tokunaga K. (2002)
    720. Role of low-affinity p75 receptor in nerve growth factor-inducible growth arrest of PC12 cells. (PubMed id 12210831)9 Ito H....Furukawa S. (2002)
    721. Effects of dexamethasone on cytokine plasma levels and white blood cell counts in depressed patients. (PubMed id 11070335)9 Schuld A....PollmAocher T. (2001)
    722. Nerve growth factor signaling of p75 induces differentiation and ceramide-mediated apoptosis in Schwann cells cultured from degenerating nerves. (PubMed id 11746763)9 Hirata H....Uchida A. (2001)
    723. Quantitative flow cytometry shows activation of the TNF-alpha system but not of the IL-2 system at the single cell level in renal replacement therapy. (PubMed id 11427636)9 van Riemsdijk-Van Overbeeke I.C....Weimar W. (2001)
    724. Does diabetes target ganglion neurones? Progressive sensory neurone involvement in long-term experimental diabetes. (PubMed id 11673332)9 Zochodne D.W....Johnston J. (2001)
    725. Nerve growth factor exerts differential effects on the growth of human pancreatic cancer cells. (PubMed id 11205897)9 Zhu Z.W....BA1chler M.W. (2001)
    726. [Measurement of the serum concentrations of tumor necrosis factor alpha and its soluble receptors in normal and pre-eclamptic pregnant patients] (PubMed id 11552506)9 NA_A+ez-GonzA!lez J.R....Romero-AdriA!n T. (2001)
    727. Leukocyte, platelet and endothelial activation in patients with acute renal failure treated by intermittent hemodialysis. (PubMed id 11509797)9 de SA! H.M....Marques A.A. (2001)
    728. Molecular interactions between neurotrophin receptors. (PubMed id 11545260)9 Dechant G. (2001)
    729. Genetic analysis as a valuable key to diagnosis and t reatment of periodic Fever. (PubMed id 11700162)9 Simon A....Drenth J.P. (2001)
    730. Activation of JNK and transcriptional repressor ATF3/LRF1 through the IRE1/TRAF2 pathway is implicated in human vascular endothelial cell death by homocysteine. (PubMed id 11726207)9 Zhang C....Kitajima S. (2001)
    731. Tumor necrosis factor inhibitors: new options for tre ating rheumatoid arthritis. (PubMed id 11574988)9 Moreland L.W. (2001)
    732. Proinflammatory cytokine inhibitors, TNF-alpha and oxidative burst of polymorphonuclear leukocytes in the pathogenesis of sepsis in newborns. (PubMed id 11348020)9 Sikora J.P....Chrul S. (2001)
    733. Expression of proinflammatory cytokines and their inhibitors during the course of spontaneous bacterial peritonitis. (PubMed id 11508666)9 RodrA-guez-Ramos C....GirA^n-GonzA!lez J.A. (2001)
    734. Endogenous nitric oxide and soluble tumor necrosis factor receptor levels are enhanced in infants with congenital heart disease. (PubMed id 11700425)9 Buchhorn R....Loppnow H. (2001)
    735. Activation of peripheral blood neutrophils from patients with active advanced tuberculosis. (PubMed id 11414749)9 AlemA!n M....Sasiain M.C. (2001)
    736. Effects of sleep on endotoxin-induced host responses in healthy men. (PubMed id 11485110)9 Haack M....PollmAocher T. (2001)
    737. Gene expression of tumor necrosis factor alpha and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients. (PubMed id 11732005)9 Crespo J....Pons-Romero F. (2001)
    738. Expression of different NF-kappaB pathway genes in dendritic cells (DCs) or macrophages assessed by gene expression profiling. (PubMed id 11573245)9 Baltathakis I....Boldt D.H. (2001)
    739. TNF blockade in the treatment of rheumatoid arthritis : infliximab versus etanercept. (PubMed id 11336570)9 Mikuls T.R. and Moreland L.W. (2001)
    740. Limited efficacy of thalidomide in the treatment of febrile attacks of the hyper-IgD and periodic fever syndrome: a randomized, double-blind, placebo-controlled trial. (PubMed id 11504824)9 Drenth J.P....van der Meer J.W. (2001)
    741. Cytokines in rheumatoid arthritis: trials and tribula tions. (PubMed id 10904249)9 Carteron N.L. (2000)
    742. Non-linear cortico-cortical interactions modulated by cholinergic afferences from the rat basal forebrain. (PubMed id 11164650)9 Villa A.E....Vantini G. (2000)
    743. Modulation of endometrial steroid receptors and growth regulatory genes by tamoxifen. (PubMed id 10775732)9 Elkas J....Gray K. (2000)
    744. [TNF alpha and heart failure] (PubMed id 11253333)9 Pergola V....Iacono A. (2000)
    745. Systemic lupus erythematosus candidate genes in the Italian population: evidence for a significant association with interleukin-10. (PubMed id 10643707)9 D'Alfonso S....Momigliano-Richardi P. (2000)
    746. Toremifene increases the expression of intercellular adhesion molecule-1 (ICAM-1) on MCF-7 breast cancer cells and Jurkat cells. (PubMed id 10632979)9 Komi J. and Lassila O. (2000)
    747. An analysis of 14 molecular markers for monitoring osteoarthritis: segregation of the markers into clusters and distinguishing osteoarthritis at baseline. (PubMed id 10806045)9 Otterness I.G....Weiner E. (2000)
    748. Highly active antiretroviral therapy (HAART) and circulating markers of immune activation: specific effect of HAART on neopterin. (PubMed id 10973464)9 Amirayan-Chevillard N....Capo C. (2000)
    749. Gene expression of TNF-receptors in peripheral blood mononuclear cells of patients with alcoholic cirrhosis. (PubMed id 10673067)9 Hanck C....Rossol S. (2000)
    750. Etanercept in children with polyarticular juvenile rheumatoid arthritis. Pediatric Rheumatology Collaborative Study Group. (PubMed id 10717011)9 Lovell D.J....Finck B.K. (2000)
    751. Lupus susceptibility genes on human chromosome 1. (PubMed id 11016422)9 Tsao B.P. (2000)
    752. Physical and functional interaction of filamin (actin-binding protein-280) and tumor necrosis factor receptor-associated factor 2. (PubMed id 10617615)9 Leonardi A....Siebenlist U. (2000)
    753. Neurotrophin regulation of sodium and calcium channels in human neuroblastoma cells. (PubMed id 10683584)9 Urbano F.J. and BuA+o W. (2000)
    754. TNF-alpha-induced secretion of C-C chemokines modulates C-C chemokine receptor 5 expression on peripheral blood lymphocytes. (PubMed id 10843668)9 Hornung F....Lenardo M.J. (2000)
    755. TNF-alpha and its receptors mediate graft rejection and loss after liver transplantation. (PubMed id 11156356)9 Grenz A....Viebahn R. (2000)
    756. Expression of genes coding for the tumor necrosis factor and lymphotoxin ligand-receptor system in non-Hodgkin's lymphomas. (PubMed id 11092613)9 Warzocha K....Salles G. (2000)
    757. Effect of coadministration of clozapine and fluvoxami ne versus clozapine monotherapy on blood cell counts, plasma levels of cytokine s and body weight. (PubMed id 10805611)9 Hinze-Selch D....PollmAocher T. (2000)
    758. Tumor necrosis factor-alpha-induced lung cell expression of antiapoptotic genes TRAF1 and cIAP2. (PubMed id 10657935)9 Pryhuber G.S....O'Reilly M.A. (2000)
    759. Activation of p55 tumor necrosis factor-alpha receptor-1 coupled to tumor necrosis factor receptor-associated factor 2 stimulates intercellular adhesion molecule-1 expression by modulating a thapsigargin-sensitive pathway in human tracheal smooth muscle cells. (PubMed id 10860946)9 Amrani Y....Panettieri R.A. (2000)
    760. Ablation of tumor necrosis factor receptor type I (p55) alters oxygen-induced lung injury. (PubMed id 10781441)9 Pryhuber G.S....Nahm M.H. (2000)
    761. High cytosolic pool of p75 TNF receptors and delayed surface downmodulation by mononuclear cells from non-hodgkin's lymphoma patients. (PubMed id 10880265)9 Rathore V.B....Nadkarni J.J. (2000)
    762. Soluble cytokine receptors: novel immunotherapeutic a gents. (PubMed id 11060691)9 Fernandez-Botran R. (2000)
    763. [Analysis of susceptibility genes to rheumatic diseases] (PubMed id 10077998)9 Tsuchiya N. and Tokunaga K. (1999)
    764. A prospective randomized study of the systemic immune response after laparoscopic and conventional Nissen fundoplication. (PubMed id 10418585)9 Sietses C....Cuesta M.A. (1999)
    765. Occurrence of cytokine receptors on different lymphoid leukaemic cells. (PubMed id 10414448)9 Koubek K....Filipec M. (1999)
    766. Progressive and selective changes in neurotrophic factor expression and substance p axonal transport induced by perinatal diabetes: protective action of antioxidant treatment. (PubMed id 10440901)9 Germani E....Gorio A. (1999)
    767. LPS mediated production of IL-1, PGE2 and PGF2alpha f rom term decidua involves tumour necrosis factor and tumour necrosis factor rec eptor p55. (PubMed id 10674980)9 Arntzen K.J....Austgulen R. (1999)
    768. Etanercept and methotrexate combination therapy. (PubMed id 10589361)9 Bankhurst A.D. (1999)
    769. A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. (PubMed id 9920948)9 Weinblatt M.E....Burge D.J. (1999)
    770. Cytokine gene expression in peripheral blood mononuclear cells reflects a systemic immune response in alcoholic chronic pancreatitis. (PubMed id 10732290)9 Hanck C....Singer M.V. (1999)
    771. Tumor necrosis factor receptor and Fas signaling mechanisms. (PubMed id 10358762)9 Wallach D....Boldin M.P. (1999)
    772. Binding of tumour necrosis factor-alpha (TNF-alpha) to TNF-RI induces caspase(s)-dependent apoptosis in human cholangiocarcinoma cell lines. (PubMed id 10209503)9 Utaisincharoen P....Sirisinha S. (1999)
    773. Etanercept therapy in rheumatoid arthritis. A randomized, controlled trial. (PubMed id 10075615)9 Moreland L.W....Weinblatt M.E. (1999)
    774. Role of the 75-kDa TNF receptor in TNF-induced activation of neutrophil respiratory burst. (PubMed id 9886420)9 Dri P....Patriarca P. (1999)
    775. The Fanconi anemia group C gene product modulates apoptotic responses to tumor necrosis factor-alpha and Fas ligand but does not suppress expression of receptors of the tumor necrosis factor receptor superfamily. (PubMed id 9923438)9 Koh P.S....Bagby G.C. (1999)
    776. Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF. (PubMed id 10357816)9 Grell M....Strasser A. (1999)
    777. Detection of macrophage inflammatory protein (MIP)-1alpha and MIP-1beta during experimental endotoxemia and human sepsis. (PubMed id 9841832)9 O'Grady N.P....Suffredini A.F. (1999)
    778. Etanercept, a novel drug for the treatment of patients with severe, active rheumatoid arthritis. (PubMed id 10090426)9 Goldenberg M.M. (1999)
    779. A p75 tumor necrosis factor receptor-specific mutant of murine tumor necrosis factor alpha expressed from an adenovirus vector induces an antitumor response with reduced toxicity. (PubMed id 10505857)9 Marr R.A....Graham F.L. (1999)
    780. Plasma levels of the soluble fraction of tumor necrosis factor receptor 2 and insulin resistance. (PubMed id 9792545)9 FernA!ndez-Real J.M....Richart C. (1998)
    781. Multiple sclerosis: expression of molecules of the tumor necrosis factor ligand and receptor families in relationship to the demyelinated plaque. (PubMed id 9809372)9 Raine C.S....Cannella B. (1998)
    782. Soluble tumor necrosis factor receptor (p75) fusion p rotein (ENBREL) as a therapy for rheumatoid arthritis. (PubMed id 9710888)9 Moreland L.W. (1998)
    783. Neural architecture in transected rabbit sciatic nerv e after prolonged nonreinnervation. (PubMed id 9723980)9 Bradley J.L....Thomas P.K. (1998)
    784. Shedding of tumour necrosis factor receptors from purified villous term trophoblasts and cytotrophoblastic BeWo cells. (PubMed id 9756317)9 KnAPfler M....Husslein P. (1998)
    785. The mRNA expression of cytokines and their receptors in cultured iris pigment epithelial cells: a comparison with retinal pigment epithelial cells. (PubMed id 9733590)9 Kociok N....Heimann K. (1998)
    786. Peg3/Pw1 is an imprinted gene involved in the TNF-NFkappaB signal transduction pathway. (PubMed id 9500555)9 Relaix F....Sassoon D.A. (1998)
    787. Induction of tumour necrosis factor (TNF) receptor type p55 and p75 in patients with chronic hepatitis C virus (HCV) infection. (PubMed id 9486392)9 Kallinowski B....Rossol S. (1998)
    788. Gene expression by single Reed-Sternberg cells: pathways of apoptosis and activation. (PubMed id 9516144)9 Messineo C....Cossman J. (1998)
    789. TRAF-4 expression in epithelial progenitor cells. Analysis in normal adult, fetal, and tumor tissues. (PubMed id 9626059)9 Krajewska M.... Reed J.C. (1998)
    790. Cloning and sequencing of cDNA encoding bovine tumor necrosis factor (TNF)-receptor I. (PubMed id 9613449)9 Lee E.K....Taylor M.J. (1998)
    791. Neurotrophins: the biological paradox of survival factors eliciting apoptosis. (PubMed id 10200484)9 Casaccia-Bonnefil P....Chao M.V. (1998)
    792. Prevention of collagen-induced arthritis by gene delivery of soluble p75 tumour necrosis factor receptor. (PubMed id 10023437)9 Mageed R.A....Chernajovsky Y. (1998)
    793. The influence of human endotoxemia on CD95-induced apoptosis. (PubMed id 9865650)9 Lin E....Lowry S.F. (1998)
    794. A metalloproteinase inhibitor blocks the shedding of soluble cytokine receptors and processing of transmembrane cytokine precursors in human monocytic cells. (PubMed id 9195133)9 Gallea-Robache S....Roman-Roman S. (1997)
    795. Analysis of myeloid-associated genes in human hematopoietic progenitor cells. (PubMed id 9328452)9 Bello-Fernandez C....Knapp W. (1997)
    796. A matrix metalloproteinase inhibitor prevents processing of tumor necrosis factor alpha (TNF alpha) and abrogates endotoxin-induced lethality. (PubMed id 9185243)9 Solorzano C.C....Moldawer L.L. (1997)
    797. Polymorphisms of tumor necrosis factor receptor 2 are not associated with insulin-dependent diabetes mellitus or Graves' disease. (PubMed id 9174153)9 Rau H....Badenhoop K. (1997)
    798. Neurotrophins and their receptors in nerve injury and repair. (PubMed id 9106250)9 Ebadi M....Lassi N.K. (1997)
    799. Involvement of a common 10-amino-acid segment in the cytoplasmic region of CD40 but different MAP kinases in different CD40-mediated responses. (PubMed id 9144420)9 Hara T....Uede T. (1997)
    800. A recombinant tumor necrosis factor-alpha p80 receptor:Fc fusion protein decreases circulating bioactive tumor necrosis factor-alpha but not lung injury or mortality during immunosuppression-related gram-negative bacteremia. (PubMed id 9075062)9 Lechner A.J....Matuschak G.M. (1997)
    801. A differential role for interleukin-6 and tumor necrosis factor-alpha in schizophrenia? (PubMed id 9323355)9 Naudin J....Azorin J.M. (1997)
    802. [Neurotrophic factors and their receptor expressions in human neuropathies] (PubMed id 9577659)9 Sobue G. (1997)
    803. Soluble tumor necrosis factor receptors and interleukin-6 levels in patients with severe preeclampsia. (PubMed id 8752252)9 Kupferminc M.J....Socol M.L. (1996)
    804. Expression of tumor necrosis factor-receptor superfamily members by lung T lymphocytes in interstitial lung disease. (PubMed id 8616567)9 Agostini C....Semenzato G. (1996)
    805. Interleukin 1 (IL-1) receptor antagonist, soluble tumor necrosis factor receptors, IL-1 beta, and IL-8--markers of remission in rheumatoid arthritis during treatment with methotrexate. (PubMed id 8877917)9 Seitz M....Gerber N.J. (1996)
    806. Different pattern of local and systemic release of pr oinflammatory and anti-inflammatory mediators in severely injured patients with chest trauma. (PubMed id 8656476)9 Keel M....Ertel W. (1996)
    807. Synergistic induction of endothelial tissue factor by tumor necrosis factor and vascular endothelial growth factor: functional analysis of the tumor necrosis factor receptors. (PubMed id 8706889)9 Clauss M....Risau W. (1996)
    808. Structures of the extracellular domain of the type I tumor necrosis factor receptor. (PubMed id 8939750)9 Naismith J.H.... Sprang S.R. (1996)
    809. The relationship between plasminogen activator inhibitor-1 and proinflammatory and counterinflammatory mediators in children with meningococcal septic shock. (PubMed id 8627066)9 Kornelisse Groot R. (1996)
    810. Increased production of nitric oxide in patients with hemorrhagic fever with renal syndrome--relation to arterial hypotension and tumor necrosis factor. (PubMed id 8923042)9 Linderholm M....TAornvik A. (1996)
    811. Nerve growth factor (NGF)-mediated protection of neural crest cells from antimitotic agent-induced apoptosis: the role of the low-affinity NGF receptor. (PubMed id 8656283)9 Cortazzo M.H....Schor N.F. (1996)
    812. Assessment of oxygen radicals during kidney transplantation--effect of radical scavenger. (PubMed id 8959891)9 Hower R....Land W. (1996)
    813. Peripheral natural killer cell activity and intraperitoneal soluble p55 tumor necrosis factor receptor in patients with malignant ascites: two possible indicators for response to intraperitoneal combined tumor necrosis factor alpha and interferon gamma treatment. (PubMed id 8625364)9 Ott M.G....Raeth U. (1996)
    814. Effects of clozapine on plasma cytokine and soluble c ytokine receptor levels. (PubMed id 8889915)9 PollmAocher T....Mullington J. (1996)
    815. The role of receptors for tumour necrosis factor-alpha in the induction of human polymorphonuclear neutrophil chemiluminescence. (PubMed id 8946217)9 Zeman K....TchA^rzewski H. (1996)
    816. Chronic infusion of nerve growth factor into rat striatum increases cholinergic markers and inhibits striatal neuronal discharge rate. (PubMed id 8921273)9 FAPrander P....StrAPmberg I. (1996)
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    818. Exploring cell death mechanisms by analyzing signaling cascades of the TNF/NGF receptor family. (PubMed id 8950472)9 Wallach D....Varfolomeev E. (1996)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 7133 HGNC: 11917 AceView: TNFRSF1B Ensembl:ENSG00000028137 euGenes: HUgn7133
    ECgene: TNFRSF1B Kegg: 7133 H-InvDB: TNFRSF1B

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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    PharmGKB entry for TNFRSF1B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TNFRSF1B Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
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    Patent Information for TNFRSF1B gene:
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