Aliases for TNFAIP8L3 Gene
External Ids for TNFAIP8L3 Gene
Previous GeneCards Identifiers for TNFAIP8L3 Gene
GeneCards Summary for TNFAIP8L3 Gene
TNFAIP8L3 (Tumor Necrosis Factor, Alpha-Induced Protein 8-Like 3) is a Protein Coding gene. An important paralog of this gene is TNFAIP8.
UniProtKB/Swiss-Prot for TNFAIP8L3 Gene
Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling.