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TNFAIP8L2 Gene

protein-coding   GIFtS: 45
GCID: GC01P151129

Tumor Necrosis Factor, Alpha-Induced Protein 8-Like 2

  Search for TNFAIP8L2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tumor Necrosis Factor, Alpha-Induced Protein 8-Like 21 2     TNFAIP8-Like Protein 22 3
TIPE22 3 5     Inflammation Factor 202
Inflammation Factor Protein 202 3     Tumor Necrosis Factor Alpha-Induced Protein 8-Like Protein 22
TNF Alpha-Induced Protein 8-Like Protein 22 3     Tumor Necrosis Factor, Alpha-Induced Protein 8-Like Protein 22

External Ids:    HGNC: 262771   Entrez Gene: 796262   Ensembl: ENSG000001631547   OMIM: 6121125   UniProtKB: Q6P5893   

Export aliases for TNFAIP8L2 gene to outside databases

Previous GC identifers: GC01P147943 GC01P149395 GC01P122507


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TNFAIP8L2 Gene:
TNFAIP8L2 (tumor necrosis factor, alpha-induced protein 8-like 2) is a protein-coding gene. An important paralog of this gene is TNFAIP8.

UniProtKB/Swiss-Prot: TP8L2_HUMAN, Q6P589
Function: Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative
regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system
and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_004487.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the TNFAIP8L2 gene promoter:
         PPAR-alpha   Spz1   Tal-1   MAZR   RREB-1   Olf-1   Nkx2-5   TGIF   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): TNFAIP8L2 promoter sequence
   Search Chromatin IP Primers for TNFAIP8L2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TNFAIP8L2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21.3   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q21.2

TNFAIP8L2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TNFAIP8L2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P151129:  view genomic region     (about GC identifiers)

Start:
151,129,105 bp from pter      End:
151,132,225 bp from pter
Size:
3,121 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TP8L2_HUMAN, Q6P589 (See protein sequence)
Recommended Name: Tumor necrosis factor alpha-induced protein 8-like protein 2  
Size: 184 amino acids; 20556 Da
Subunit: May interact with CASP8; however, such result is unclear since PubMed:19079267 could not reproduce the
interaction with CASP8
Sequence caution: Sequence=AAG44785.1; Type=Frameshift; Positions=117;
1 PDB 3D structure from and Proteopedia for TNFAIP8L2:
3F4M (3D)    
Secondary accessions: Q6I9Y0 Q9H2H7 Q9H5G2

Explore the universe of human proteins at neXtProt for TNFAIP8L2: NX_Q6P589

Explore proteomics data for TNFAIP8L2 at MOPED


See TNFAIP8L2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_078851.2  
ENSEMBL proteins: 
 ENSP00000357906  

TNFAIP8L2 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR008477 DUF758

Graphical View of Domain Structure for InterPro Entry Q6P589

ProtoNet protein and cluster: Q6P589

UniProtKB/Swiss-Prot: TP8L2_HUMAN, Q6P589
Domain: The central region was initially thought to constitute a DED (death effector) domain. However,
3D-structure data reveal a previously uncharacterized fold that is different from the predicted fold of a DED
(death effector) domain. It consists of a large, hydrophobic central cavity that is poised for cofactor binding
Similarity: Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily


Find genes that share domains with TNFAIP8L2           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: TP8L2_HUMAN, Q6P589
Function: Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative
regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system
and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By
similarity)

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005515protein binding IPI--
     
Find genes that share ontologies with TNFAIP8L2           About GenesLikeMe


Phenotypes:
     1 GenomeRNAi human phenotype for TNFAIP8L2:
 Increased S DNA content, incre 

     9 MGI mutant phenotypes (inferred from 1 allele(MGI details for Tnfaip8l2):
 cellular  digestive/alimentary  growth/size/body  hematopoietic system  homeostasis/metabolism 
 immune system  liver/biliary system  mortality/aging  respiratory system 

Find genes that share phenotypes with TNFAIP8L2           About GenesLikeMe

Animal Models:
     MGI mouse knock-out Tnfaip8l2tm1Yhcn for TNFAIP8L2

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TNFAIP8L2
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4 qRT-PCR Assays for microRNAs that regulate TNFAIP8L2:
hsa-miR-4264 hsa-miR-1244 hsa-miR-185* hsa-miR-1299
SwitchGear 3'UTR luciferase reporter plasmidTNFAIP8L2 3' UTR sequence
Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat TNFAIP8L2

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GenScript: all cDNA clones in your preferred vector: TNFAIP8L2 (NM_024575)
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TNFAIP8L2

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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNFAIP8L2


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol2
nucleus2
mitochondrion1

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005737cytoplasm IEA--

Find genes that share ontologies with TNFAIP8L2           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TNFAIP8L2
Interactions:

    Search GeneGlobe Interaction Network for TNFAIP8L2

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

3 Interacting proteins for TNFAIP8L2 (Q6P5891, 3 ENSP000003579064) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
CASP8Q147903, ENSP000003512734I2D: score=2 STRING: ENSP00000351273
RAC1P630001EBI-9073209,EBI-413628
CASP10ENSP000002861864STRING: ENSP00000286186
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Gene Ontology (GO): 3 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0045087innate immune response IEA--
GO:0050728negative regulation of inflammatory response IEA--
GO:0050868negative regulation of T cell activation IEA--

Find genes that share ontologies with TNFAIP8L2           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for TNFAIP8L2 (TP8L2)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for TNFAIP8L2 gene: 
NM_024575.4  

Unigene Cluster for TNFAIP8L2:

Tumor necrosis factor, alpha-induced protein 8-like 2
Hs.432360  [show with all ESTs]
Unigene Representative Sequence: BC063014
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000368910(uc001ewx.2)
miRNA
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Block miRNA regulation of human, mouse, rat TNFAIP8L2 using miScript Target Protectors
4 qRT-PCR Assays for microRNAs that regulate TNFAIP8L2:
hsa-miR-4264 hsa-miR-1244 hsa-miR-185* hsa-miR-1299
SwitchGear 3'UTR luciferase reporter plasmidTNFAIP8L2 3' UTR sequence
Inhib. RNA
Products:
     
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Predesigned siRNA for gene silencing in human, mouse, rat TNFAIP8L2
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TNFAIP8L2
Primer
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OriGene qPCR primer pairs and template standards for TNFAIP8L2
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Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TNFAIP8L2
  QuantiTect SYBR Green Assays in human, mouse, rat TNFAIP8L2
  QuantiFast Probe-based Assays in human, mouse, rat TNFAIP8L2

Additional mRNA sequence: 

AF271774.1 AK027120.1 AK225472.1 BC012013.2 BC063014.1 

7 DOTS entries:

DT.313060  DT.121409556  DT.75183784  DT.121409579  DT.75113669  DT.121409566  DT.70105220 

Selected AceView cDNA sequences (see all 241):

F30918 BQ013374 BQ936887 BF594059 BC012013 BE207308 AI357271 AL833373 
BU736413 AI090123 BM745075 AA085630 AW006145 AI471219 AI597799 BU730826 
BX357796 AI298776 CR607615 BC000264 NM_001002234 BQ574859 BM826325 BU754466 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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TNFAIP8L2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TGAACCAAGG
TNFAIP8L2 Expression
About this image


TNFAIP8L2 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 3) fully expand
 
 Smooth Muscle (Muscoskeletal System)
         Juxtaglomerular Cells Afferent Arteriole
 
 Kidney (Urinary System)
         Juxtaglomerular Cells Afferent Arteriole
 
 Spleen (Hematopoietic System)
TNFAIP8L2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

TNFAIP8L2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.432360
    Custom PCR Arrays for TNFAIP8L2
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNFAIP8L2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for TNFAIP8L2 gene from Selected species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Tnfaip8l21 , 5 tumor necrosis factor, alpha-induced protein 8-like more1, 5 86.23(n)1
94.02(a)1
  3 (40.74 cM)5
697691  NM_027206.21  NP_081482.11 
 951395215 
lizard
(Anolis carolinensis)
Reptilia TNFAIP8L26
tumor necrosis factor, alpha-induced protein 8-lik...
66(a)
1 ↔ 1
GL343668.1(211517-212077)
tropical clawed frog
(Xenopus tropicalis)
Amphibia tnfaip8l21 tumor necrosis factor, alpha-induced protein 8-like more 63.59(n)
63.59(a)
  595002  NM_001030443.1  NP_001025614.1 
zebrafish
(Danio rerio)
Actinopterygii tnfaip8l2b1 tumor necrosis factor, alpha-induced protein 8, like more 62.66(n)
63.39(a)
  393345  NM_200374.1  NP_956668.1 
fruit fly
(Drosophila melanogaster)
Insecta CG40916
--
34(a)
1 → many
2R(19586469-19589924)


ENSEMBL Gene Tree for TNFAIP8L2 (if available)
TreeFam Gene Tree for TNFAIP8L2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for TNFAIP8L2 gene
TNFAIP82  TNFAIP8L32  TNFAIP8L12  
3 SIMAP similar genes for TNFAIP8L2 using alignment to 1 protein entry:     TP8L2_HUMAN:
TNFAIP8    TNFAIP8L3    TNFAIP8L1

Find genes that share paralogs with TNFAIP8L2           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Structural Variations
     Database of Genomic Variants (DGV) 2 variations for TNFAIP8L2:    About this table    
Variant IDTypeSubtypePubMed ID
dgv2n68CNV Loss17160897
nsv522840CNV Gain19592680

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing TNFAIP8L2
DNA2.0 Custom Variant and Variant Library Synthesis for TNFAIP8L2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 612112    OMIM disorders: --


Find genes that share disorders with TNFAIP8L2           About GenesLikeMe


Export disorders for TNFAIP8L2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for TNFAIP8L2 gene, integrated from 10 sources (see all 15):
(articles sorted by number of sources associating them with TNFAIP8L2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. TIPE2, a novel biomarker for clinical chronic kidney allograft rejection. (PubMed id 23009108)1 Jia L....Ou Y. (Artif Organs 2013)
  2. The expression and significance of TIPE2 in peripheral blood mononuclear cells from asthmatic children. (PubMed id 24107080)1 Ma Y....Wang X. (Scand. J. Immunol. 2013)
  3. The anti-inflammatory TIPE2 is an inhibitor of the oncogenic Ras. (PubMed id 22326055)1 Gus-Brautbar Y....Chen Y.H. (Mol. Cell 2012)
  4. The unique expression profile of human TIPE2 suggests new functions beyond its role in immune regulation. (PubMed id 21459448)1 Zhang L....Zhang L. (Mol. Immunol. 2011)
  5. Roles of TIPE2 in hepatitis B virus-induced hepatic inflammation in humans and mice. (PubMed id 21466895)1 Xi W....Liu S. (Mol. Immunol. 2011)
  6. Tissue-specific expression of TIPE2 provides insights into its function. (PubMed id 20663561)1 Zhang G....Liu S. (Mol. Immunol. 2010)
  7. Crystal structure of TIPE2 provides insights into immune homeostasis. (PubMed id 19079267)2 Zhang X.... Shi Y. (Nat. Struct. Mol. Biol. 2009)
  8. TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis. (PubMed id 18455983)2 Sun H.... Chen Y.H. (Cell 2008)
  9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
  10. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (Nature 2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 79626 HGNC: 26277 AceView: SCNM1andFLJ23467 Ensembl:ENSG00000163154 euGenes: HUgn79626
ECgene: TNFAIP8L2 H-InvDB: TNFAIP8L2

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for TNFAIP8L2 Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for TNFAIP8L2 Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for TNFAIP8L2 gene:
Search GeneIP for patents involving TNFAIP8L2

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 OriGene Antibodies for TNFAIP8L2   OriGene RNAi products in human, mouse, rat for TNFAIP8L2  
 OriGene qPCR primer pairs and template standards for TNFAIP8L2   OriGene Protein Over-expression Lysate for TNFAIP8L2  
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 OriGene Custom Antibody Services for TNFAIP8L2   OriGene Custom Protein Services for TNFAIP8L2  

 
 
 Block miRNA regulation of human, mouse, rat TNFAIP8L2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TNFAIP8L2
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TNFAIP8L2 Predesigned siRNA for gene silencing in human, mouse, rat TNFAIP8L2
 QuantiFast Probe-based Assays in human, mouse, rat TNFAIP8L2 QuantiTect SYBR Green Assays in human, mouse, rat TNFAIP8L2
 Custom PCR Arrays for TNFAIP8L2 Search Chromatin IP Primers for TNFAIP8L2
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TNFAIP8L2  Search GeneGlobe Interaction Network for TNFAIP8L2
 Regulatory tfbs in TNFAIP8L2 promoter
 GenScript Custom Purified and Recombinant Proteins Services for TNFAIP8L2 GenScript cDNA clones with any tag delivered in your preferred vector for TNFAIP8L2
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 Search Tocris compounds for TNFAIP8L2 (TP8L2)
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
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 See all of Abcam's Antibodies, Kits and Proteins for TNFAIP8L2
 Custom Antibody / Protein Production Service
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 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Browse Proteins at Cloud-Clone Corp.
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 Browse ESI BIO Cell Lines and PureStem Progenitors for TNFAIP8L2
 Gene Synthesis
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 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNFAIP8L2
 SwitchGear 3'UTR luciferase reporter plasmids for TNFAIP8L2
 SwitchGear Promoter luciferase reporter plasmids for TNFAIP8L2
 Search ThermoFisher Antibodies for TNFAIP8L2
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TNFAIP8L2
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TNFAIP8L2
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TNFAIP8L2
 LSBio Antibodies in human, mouse, rat for TNFAIP8L2
Customized transgenic rodents for:
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 Browse compounds at ApexBio
 Search Addgene for plasmids for TNFAIP8L2
  Search eBioscience for proteins for TNFAIP8L2
  Search eBioscience for elisas for TNFAIP8L2
  eBioscience FlowRNA Probe Sets
       
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