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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TNFAIP2 Gene

protein-coding   GIFtS: 55
GCID: GC14P103592

tumor necrosis factor, alpha-induced protein 2
 Explore 14 diseases affiliated with
TNFAIP2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TNFAIP2    

Aliases
for TNFAIP2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Tumor Necrosis Factor, Alpha-Induced Protein 21 2     TNF Alpha-Induced Protein 22 3
B941 2     Exocyst Complex Component 3-Like 32
EXOC3L31 2     Tumor Necrosis Factor Alpha-Induced Protein 22
Primary Response Gene B94 Protein2 3     

External Ids:    HGNC: 118951   Entrez Gene: 71272   Ensembl: ENSG000001852157   OMIM: 6033005   UniProtKB: Q031693   

Export aliases for TNFAIP2 gene to outside databases

Previous GC identifers: GC14P100983 GC14P097408 GC14P101579 GC14P101582 GC14P102662 GC14P083771


Summaries
for TNFAIP2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TNFAIP2:
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in
umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line
expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may
be a retinoic acid target gene in acute promyelocytic leukemia. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: TNAP2_HUMAN, Q03169
Function: May play a role as a mediator of inflammation and angiogenesis




Genomic Views
for TNFAIP2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TNFAIP2 gene promoter:
         SRF   GR   HSF1 (long)   Lmo2   Tal-1beta   CRE-BP1   c-Myb   HSF1short   GR-alpha   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TNFAIP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for TNFAIP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TNFAIP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32   Ensembl cytogenetic band:  14q32.32   HGNC cytogenetic band: 14q32

TNFAIP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TNFAIP2 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P103592:  view genomic region     (about GC identifiers)

Start:
 103,589,779 bp from pter      End:
 103,603,776 bp from pter
Size:
 13,998 bases      Orientation:
 plus strand

Proteins
for TNFAIP2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TNAP2_HUMAN, Q03169 (See protein sequence)
Recommended Name: Tumor necrosis factor alpha-induced protein 2  
Size: 654 amino acids; 72661 Da
Developmental stage: Differentially expressed in development and capillary tube-like formation in vitro
Secondary accessions: Q86VI0

Explore the universe of human proteins at neXtProt for TNFAIP2: NX_Q03169

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q03169

    • TNFAIP2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006282.2  
    ENSEMBL proteins: 
     ENSP00000453103   ENSP00000452634   ENSP00000452824   ENSP00000452992   ENSP00000453142  
     ENSP00000453458   ENSP00000452914   ENSP00000332326   ENSP00000393256   ENSP00000446171  

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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space TAS1374453


    TNFAIP2 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for TNFAIP2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TNFAIP2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR010326 Sec6

    Graphical View of Domain Structure for InterPro Entry Q03169

    ProtoNet protein and cluster: Q03169

    1 Blocks protein family: IPB010326 Exocyst complex component Sec6

    UniProtKB/Swiss-Prot: TNAP2_HUMAN, Q03169
    Similarity: Belongs to the SEC6 family


    Function
    for TNFAIP2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: TNAP2_HUMAN, Q03169
    Function: May play a role as a mediator of inflammation and angiogenesis
    Induction: By TNF and other proinflammatory factors

         Genatlas biochemistry entry for TNFAIP2:
    tumor necrosis factor alpha,inducible primary response,2

    miRNA
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    hsa-mir-30a (MIRT005196)

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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate TNFAIP2:
    hsa-miR-3163 hsa-miR-548d-3p hsa-miR-520d-5p hsa-miR-524-5p hsa-miR-619
    SwitchGear 3'UTR luciferase reporter plasmid: TNFAIP2 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TNFAIP2 (see all 7)
    OriGene shRNA RFP: TNFAIP2
    OriGene siRNA: TNFAIP2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TNFAIP2

    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for TNFAIP2

    In Situ Assay
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    3 GenomeRNAi human phenotypes for TNFAIP2:
     Decreased Hepatitis C virus re  Increased HPV18 LCR reporter a  Upregulation of NF-kappaB path 


    Pathways & Interactions
    for TNFAIP2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TNFAIP2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5/526 Interacting proteins for TNFAIP2 (Q031692 ENSP000003323264) via UniProtKB, MINT, STRING, and/or I2D (see all 526)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CDC5LQ994592, ENSP000003605324MINT-7947479 STRING: ENSP00000360532
    ABCF1Q8NE712MINT-7947479
    ABCF3Q9NUQ82MINT-7947479
    ACTBP607092MINT-7947479
    ACTL6AO960192MINT-7947479
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001525angiogenesis IEA--
    GO:0030154cell differentiation IEA--


    TNFAIP2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TNFAIP2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TNFAIP2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TNFAIP2
    2 Novoseek chemical compound relationships for TNFAIP2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cycloheximide 52.9 1 1374453 (1)
    retinoic acid 46.1 9 10766166 (5), 12894236 (1)

    Search CenterWatch for drugs/clinical trials and news about TNFAIP2 / TNAP2 

    Transcripts
    for TNFAIP2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TNFAIP2 gene: 
    NM_006291.2  

    Unigene Clusters for TNFAIP2:

    Tumor necrosis factor, alpha-induced protein 2
    Hs.525607  [show with all ESTs], Hs.736562  [show with all ESTs]
    Unigene Representative Sequences: NM_006291, BX346984
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000559195(uc001yml.1) ENST00000558056 ENST00000560869 ENST00000560562
    ENST00000559406 ENST00000560428 ENST00000560670 ENST00000561156 ENST00000559255
    ENST00000561217 ENST00000333007(uc001ymm.1 uc010awo.1 uc010txz.1)
    ENST00000451723 ENST00000538222(uc010tya.1)

    miRNA
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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate TNFAIP2:
    hsa-miR-3163 hsa-miR-548d-3p hsa-miR-520d-5p hsa-miR-524-5p hsa-miR-619
    SwitchGear 3'UTR luciferase reporter plasmid: TNFAIP2 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: TNFAIP2
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TNFAIP2
    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TNFAIP2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TNFAIP2

    Additional cDNA sequence: BC017818.1 

    11 DOTS entries:

    DT.100767834  DT.100752108  DT.92450567  DT.100760394  DT.91749383  DT.40115880  DT.95192578  DT.97801499 
    DT.100752110  DT.120783223  DT.92005493 

    24/317 AceView cDNA sequences (see all 317):

    BQ638037 CA309467 AI613435 BQ897589 AI141988 R53219 BG289102 AW512859 
    BQ685744 BM756462 AW085836 BQ917390 AA315833 CR619961 BX092264 BQ685497 
    BU528567 AA082530 AI038093 BM747838 BQ008377 BQ917320 CD367735 BM723611 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for TNFAIP2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b
    SP1:                                                                                          
    SP2:                                                                                          
    SP3:        -                                                                                 


    ECgene alternative splicing isoforms for TNFAIP2

    Expression
    for TNFAIP2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TNFAIP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACTCAGCCCG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TNFAIP2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Skeletal MuscleHyoid Arch MusclesMyoblastsSkeletal Muscle
    Skeletal MuscleMandibular Arch MusclesMyoblastsSkeletal Muscle
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See TNFAIP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TNFAIP2

    SOURCE GeneReport for Unigene clusters: Hs.525607 Hs.736562
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    In Situ
    Assay Products:     
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    Orthologs
    for TNFAIP2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for TNFAIP2 gene from 5/18 species (see all 18)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves TNFAIP21 tumor necrosis factor, alpha-induced protein 2 50.47(n)
    39.53(a)    		   423477  XM_421383.3  XP_421383.3 
    lizard
    (Anolis carolinensis)    		 Reptilia TNFAIP26
    		 --
    		 42(a)
    		 1 ↔ 1
    		 GL343232.1(405825-423001)
    zebrafish
    (Danio rerio)    		 Actinopterygii tnfaip2a1 tumor necrosis factor, alpha-induced protein 2a 41.59(n)
    27.77(a)    		   567159  NM_001030216.1  NP_001025387.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta sec66
    		 sec6
    		 16(a)
    		 1 → many
    		 2R(14512772-14515223)
    worm
    (Caenorhabditis elegans)    		 Secernentea sec-66
    		 Exocyst complex component 3
    		 14(a)
    		 1 → many
    		 II(5359535-5372105)


    ENSEMBL Gene Tree for TNFAIP2 (if available)
    TreeFam Gene Tree for TNFAIP2 (if available) 

    Paralogs
    for TNFAIP2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TNFAIP2 gene
    EXOC3L22  EXOC32  EXOC3L12  EXOC3L42  

    TNFAIP2 for paralogs           About GeneDecksing



    Genomic Variants
    for TNFAIP2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/281 NCBI SNPs in TNFAIP2 are shown (see all 281)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 14 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs124358601,2
    		H--103590683(+) CACACC/TGAAAG 1 -- us2k10--------
    rs1512928771,2
    		--103590685(+) CACCGA/GAAGCG 1 -- us2k10--------
    rs37595731,2
    		C,F,--103590772(+) CAGGCA/GCTCTG 1 -- us2k116Minor allele frequency- G:0.47NS NA CSA WA EA 1050
    rs81763551,2
    		C,F,--103590784(+) GTTTCG/ATGTCA 1 -- us2k13Minor allele frequency- A:0.03NS NA 80
    rs1844764421,2
    		--103590826(+) TCCTGC/TGGGAG 1 -- us2k10--------
    rs81763561,2
    		C,F,--103591010(+) GCTCCC/TGCGGG 1 -- us2k111Minor allele frequency- T:0.06NS NA WA 816
    rs1879771901,2
    		--103591056(+) AGTTGC/GGGCAC 1 -- us2k10--------
    rs81763571,2
    		C,F,H--103591165(+) AGGGAG/AGNNNN 1 -- us2k15Minor allele frequency- A:0.01NS NA 314
    rs749645501,2
    		--103591255(+) CCTGTC/TCCTCA 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs81763581,2
    		C,F,--103591307(+) TGGGGC/ATGGTG 1 -- us2k14Minor allele frequency- A:0.04NS NA 216

    HapMap Linkage Disequilibrium report for TNFAIP2 (103589779 - 103603776 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for TNFAIP2
         1 CNV: 4848
    Human Gene Mutation Database (HGMD): TNFAIP2

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TNFAIP2
    DNA2.0 Custom Variant and Variant Library Synthesis for TNFAIP2

    Disorders / Diseases
    for TNFAIP2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TNFAIP2 for disorders           About GeneDecksing

    OMIM gene information: 603300    OMIM disorders: --

    14 diseases for TNFAIP2:    About MalaCards
    acute promyelocytic leukemia    leukemia    primary biliary cirrhosis    b-cell lymphomas
    squamous cell carcinoma of the head and neck    squamous cell carcinoma    hodgkin's lymphoma    mediastinitis
    hepatitis b    hepatoblastoma    ovarian cancer    nasopharyngitis
    hepatitis    carcinoma

    1 disease from the University of Copenhagen DISEASES database for TNFAIP2:
    Hepatoblastoma

    2 Novoseek disease relationships for TNFAIP2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    necrosis 38.9 5 12894236 (1), 17624025 (1), 10766166 (1)
    tumors 8.63 3 12894236 (1), 10766166 (1)

    Human Genome Epidemiology (HuGE) Navigator: TNFAIP2 (9 documents)

    Export disorders for TNFAIP2 gene to outside databases

    Publications
    for TNFAIP2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TNFAIP2 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with TNFAIP2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning of a novel tumor necrosis factor-alpha-inducible primary response gene that is differentially expressed in development and capillary tube-like formation in vitro. (PubMed id 1374453)1, 2, 3, 9 Sarma V.... Dixit V.M. (1992)
    2. Identification of B94 (TNFAIP2) as a potential retinoic acid target gene in acute promyelocytic leukemia. (PubMed id 10766166)1, 9 Rusiniak M.E....Slack J.L. (2000)
    3. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    5. Genome-wide association study identifies 12 new susce ptibility loci for primary biliary cirrhosis. (PubMed id 21399635)1 Mells G.F....Anderson C.A. (2011)
    6. The BTB and CNC homology 1 (BACH1) target genes are i nvolved in the oxidative stress response and in control of the cell cycle. (PubMed id 21555518)1 Warnatz H.J....Yaspo M.L. (2011)
    7. A novel role for TNFAIP2: its correlation with invasi on and metastasis in nasopharyngeal carcinoma. (PubMed id 21057457)1 Chen L.C....Hsueh C. (2011)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. Aberrant expression of the dendritic cell marker TNFA IP2 by the malignant cells of Hodgkin lymphoma and primary mediastinal large B- cell lymphoma distinguishes these tumor types from morphologically and phenotyp ically similar lymphomas. (PubMed id 21921781)1 Kondratiev S....Rodig S.J. (2011)
    10. A functional variant at the miR-184 binding site in T NFAIP2 and risk of squamous cell carcinoma of the head and neck. (PubMed id 21934093)1 Liu Z....Wei Q. (2011)

    External Searches for TNFAIP2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing TNFAIP2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7127 HGNC: 11895 AceView: TNFAIP2 Ensembl:ENSG00000185215 euGenes: HUgn7127
    ECgene: TNFAIP2 H-InvDB: TNFAIP2

    Other Databases showing TNFAIP2 gene

    (According to HUGE)
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    Specialized Databases showing TNFAIP2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TNFAIP2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TNFAIP2 Genetics and Cytogenetics in Oncology and Haematology
    SeattleSNPshttp://pga.gs.washington.edu/data/tnfaip2/

    Intellectual Property
    for TNFAIP2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    		Patent Information for TNFAIP2 gene:
    Search GeneIP for patents involving TNFAIP2

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