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TNF Gene

protein-coding   GIFtS: 73
GCID: GC06P031543

Tumor Necrosis Factor

(Previous names: tumor necrosis factor (TNF superfamily, member 2))
(Previous symbol: TNFA)
Microbiology & Infectious Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tumor Necrosis Factor1 2     Tumor Necrosis Factor (TNF Superfamily, Member 2)1
TNFA1 2 3 5     DIF2
Tumor Necrosis Factor Ligand Superfamily Member 22 3     APC1 Protein2
TNF-a2 3     cachectin2
TNF-alpha2 3     TNF, Macrophage-Derived2
TNFSF22 3     TNF, Monocyte-Derived2
Member 21     Tumor Necrosis Factor-Alpha2
TNF Superfamily1     Cachectin3

External Ids:    HGNC: 118921   Entrez Gene: 71242   Ensembl: ENSG000002328107   OMIM: 1911605   UniProtKB: P013753   

Export aliases for TNF gene to outside databases

Previous GC identifers: GC06P031606 GC06P031597 GC06P031314 GC06P031647 GC06P031652 GC06P031330


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TNF Gene:
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF)
superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its
receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of
biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation.
This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance,
and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. (provided by
RefSeq, Jul 2008)

GeneCards Summary for TNF Gene:
TNF (tumor necrosis factor) is a protein-coding gene. Diseases associated with TNF include aphthous stomatitis, and vascular dementia. GO annotations related to this gene include cytokine activity and identical protein binding. An important paralog of this gene is FASLG.

UniProtKB/Swiss-Prot: TNFA_HUMAN, P01375
Function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can
induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by
stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions
it can stimulate cell proliferation and induce cell differentiation
Function: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells

summary for TNF Gene:
NF-kappaB (nuclear factor-kappa B) is a rapidly acting primary transcription factor found in all cell types.
It is involved in cellular responses to stimuli such as cytokines and stress and plays a key role in
regulating the immune response to infection. In unstimulated cells NF-kappaB dimers are sequestered
inactively in the cytoplasm by a protein complex called inhibitor of kappa B (IkappaB). IkappaB inactivates
NF-kappaB by masking the nuclear localization signals (NLS). Activation of NF-kappaB occurs via degradation
of IkappaB, a process that is initiated by its phosphorylation by IkappaB kinase (IKK). Phosphorylated
IkappaB becomes dissociated from NF-kappaB, unmasking the NLS. Phosphorylation also results in IkappaB
ubiquitination and targeting to the proteasome. NF-kappaB can now enter the nucleus and regulate gene
expression. NF-kappaB turns on expression of IkappaB forming a negative feedback loop.

Gene Wiki entry for TNF (Tumor necrosis factor-alpha) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NC_018917.2  NT_007592.16  NT_113891.3  NT_167244.2  NT_167245.2  NT_167246.2  NT_167247.2  
NT_167248.2  NT_167249.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TNF gene promoter:
         c-Fos   p53   AP-1   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): TNF promoter sequence
   Search Chromatin IP Primers for TNF

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TNF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p21.33   HGNC cytogenetic band: 6p21.3

TNF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TNF gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P031543:  view genomic region     (about GC identifiers)

Start:
31,543,344 bp from pter      End:
31,546,113 bp from pter
Size:
2,770 bases      Orientation:
plus strand

Selected alternative locations (see all 7):
Chr6+,NT_167246 2,886,234-2,888,996      Chr6+,NT_167248 2,836,988-2,839,752      Chr6+,NT_167247 2,923,056-2,925,818     
Chr6+,NT_167249 2,874,151-2,876,913      Chr6+,NT_167244 2,859,024-2,860,830      Chr6+,NT_167245 2,828,891-2,831,653     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TNFA_HUMAN, P01375 (See protein sequence)
Recommended Name: Tumor necrosis factor precursor  
Size: 233 amino acids; 25644 Da
Subunit: Homotrimer. Interacts with SPPL2B
Sequence caution: Sequence=AAF71992.1; Type=Frameshift; Positions=91, 157; Sequence=CAA75070.1; Type=Erroneous
gene model prediction;
Selected PDB 3D structures from and Proteopedia for TNF (see all 14):
1A8M (3D)        1TNF (3D)        2AZ5 (3D)        2E7A (3D)        2TUN (3D)        2ZJC (3D)    
Secondary accessions: O43647 Q9P1Q2 Q9UIV3

Explore the universe of human proteins at neXtProt for TNF: NX_P01375

Explore proteomics data for TNF at MOPED

Post-translational modifications: 

  • The soluble form derives from the membrane form by proteolytic processing. The membrane-bound form is further
    proteolytically processed by SPPL2A or SPPL2B through regulated intramembrane proteolysis producing TNF
    intracellular domains (ICD1 and ICD2) released in the cytosol and TNF C-domain 1 and C-domain 2 secreted into the
    extracellular space1
  • The membrane form, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the
    membrane form occurs by binding to soluble TNFRSF1A/TNFR11
  • O-glycosylated; glycans contain galactose, N-acetylgalactosamine and N-acetylneuraminic acid1
  • Glycosylation2 at Ser80
  • Modification sites at PhosphoSitePlus

  • See TNF Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_000585.2  
    ENSEMBL proteins: 
     ENSP00000398698  
    Reactome Protein details: P01375

    TNF Human Recombinant Protein Products:

    EMD Millipore Purified and/or Recombinant TNF Protein
    R&D Systems Recombinant & Natural Proteins for TNF (TNF-alpha)
    Enzo Life Sciences proteins for TNF
    OriGene Purified Proteins for TNF
    OriGene Protein Over-expression Lysate for TNF
    OriGene MassSpec for TNF
    OriGene Custom Protein Services for TNF
    GenScript Purified and Recombinant Proteins for TNF
    Novus Biologicals TNF Proteins
    Novus Biologicals TNF Lysate
    Sino Biological Recombinant Protein for TNF
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for TNF
    Browse Proteins at Cloud-Clone Corp.

    TNF Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of TNF
    R&D Systems Antibodies for TNF (TNF-alpha)
    OriGene Antibodies for TNF
    OriGene Custom Antibody Services for TNF
    Novus Biologicals TNF Antibodies
    Abcam antibodies for TNF
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibody for TNF
    LSBio Antibodies in human, mouse, rat for TNF

    TNF Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TNF
    R&D Systems Flow Cytometry Kits for TNF (TNF-alpha)         (see all)
    GenScript Custom Assay Services for TNF
    Enzo Life Sciences assays for TNF
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TNFSF: Tumor necrosis factor (ligand) superfamily

    Selected InterPro protein domains (see all 6):
     IPR008064 TNFalpha/TNFSF15
     IPR002959 TNF_alpha
     IPR006052 TNF_dom
     IPR006053 TNF
     IPR008983 Tumour_necrosis_fac-like_dom

    Graphical View of Domain Structure for InterPro Entry P01375

    ProtoNet protein and cluster: P01375

    3 Blocks protein domains:
    IPB002959 Tumour necrosis factor alpha (cachectin) signature
    IPB006052 Tumor Necrosis Factor
    IPB006053 Tumour necrosis factor family signature


    UniProtKB/Swiss-Prot: TNFA_HUMAN, P01375
    Similarity: Belongs to the tumor necrosis factor family


    TNF for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TNFA_HUMAN, P01375
    Function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can
    induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by
    stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions
    it can stimulate cell proliferation and induce cell differentiation
    Function: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells

         Genatlas biochemistry entry for TNF:
    tumor necrosis factor,alpha (cachectin),potent proinflammatory cytokine,involved in inflammatory and immune
    responses,stimulating the sphingomyelinase (SMPD1),enhancing insulin resistance in peripheral tissues of cancer
    patients,susceptibility factor for narcolepsy and myasthenia gravis and cardiac sarcoidosis,with a common
    polymorphism in the promoter region (C->A) associated with reduced circulating levels of TNF,mediating neuronal
    death in injured brain (by inducing resistance to the protective effect of IGF1)

         Summary: 
    During embryonic development, TNF as signaling molecule affects the following cells:
    Liver: Fetal Hepatocytes (Liver Lobule)

    TNF as growth factor is involved in stem cell differentiation protocols towards the derivation of the following cells:
                
    Blood: Mature dendritic-like cells, Dendritic-like cells       to see all 2 cells

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002020protease binding IPI12777399
    GO:0005125cytokine activity IDA10748004
    GO:0005164tumor necrosis factor receptor binding IDA14512626
    GO:0005515protein binding IPI11878931
    GO:0042802identical protein binding IDA14512626
         
    TNF for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TNF:
     Increased cell death in breast 

         Selected MGI mutant phenotypes (inferred from 19 alleles(MGI details for Tnf) (see all 24):
     adipose tissue  behavior/neurological  cardiovascular system  cellular  craniofacial 
     digestive/alimentary  embryogenesis  endocrine/exocrine gland  growth/size/body  hematopoietic system 
     homeostasis/metabolism  immune system  integument  limbs/digits/tail  liver/biliary system 

    TNF for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for TNF: Ltb/TnfLtb/tm1.1Dvk Lta/TnfLta/tm1Eug Tnftm1Jods Lta/TnfLta/tm1Fda Tnftm1Sek Tnftm1Gkl
                                                         Tnftm3Gkl Ltb/Tnf/LtaLtb/Tnf/tm1Dvk Tnftm2.1Gkl Tnftm1Ljo Tnftm1.2Sned Lta/TnfLta/tm1Jods Tnftm2Gkl

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TNF
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TNF

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TNF
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TNF

    miRNA
    Products:
        
    miRTarBase miRNAs that target TNF:
    hsa-mir-203a (MIRT006857)

    Block miRNA regulation of human, mouse, rat TNF using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TNF (see all 29):
    hsa-miR-549 hsa-miR-875-3p hsa-miR-181c hsa-miR-3141 hsa-miR-4263 hsa-miR-331-3p hsa-miR-301a hsa-miR-181a-2*
    SwitchGear 3'UTR luciferase reporter plasmidTNF 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TNF
    Predesigned siRNA for gene silencing in human, mouse, rat TNF

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TNF

    Clone
    Products:
         
    OriGene clones in human, mouse for TNF (see all 6)
    OriGene ORF clones in mouse, rat for TNF
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TNF (NM_001192)
    Sino Biological Human cDNA Clone for TNF
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TNF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TNF

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TNF
    Browse ESI BIO Cell Lines and PureStem Progenitors for TNF 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNF


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TNFA_HUMAN, P01375: Cell membrane; Single-pass type II membrane protein
    TNFA_HUMAN, P01375: Tumor necrosis factor, membrane form: Membrane; Single-pass type II membrane protein
    TNFA_HUMAN, P01375: Tumor necrosis factor, soluble form: Secreted
    TNFA_HUMAN, P01375: C-domain 1: Secreted
    TNFA_HUMAN, P01375: C-domain 2: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    plasma membrane5
    endosome3
    nucleus3
    cytoskeleton2
    cytosol2
    mitochondrion2
    endoplasmic reticulum1
    golgi apparatus1
    lysosome1
    peroxisome1
    vacuole1

    Gene Ontology (GO): Selected cellular component terms (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001891phagocytic cup ISS--
    GO:0005576extracellular region TAS--
    GO:0005615extracellular space IDA10443688
    GO:0005622intracellular ----
    GO:0005886plasma membrane TAS--

    TNF for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TNF About   (see all 99)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1TWEAK Pathway
    TNFR1 Pathway0.56
    Apoptotic Pathways Triggered By HIV10.42
    TNF Signaling0.55
    Apoptosis through Death Receptors0.42
    Apoptosis and survival TNFR1 signaling pathway0.52
    TWEAK Signaling Pathway0.31
    HIV-1 Nef- Negative effector of Fas and TNF-alpha0.46
    2Allograft rejection
    Allograft rejection0.86
    Asthma0.46
    Allograft Rejection0.86
    THC Differentiation Pathway0.38
    Type I diabetes mellitus0.69
    Antigen processing and presentation0.36
    Graft-versus-host disease0.65
    3Apoptosis and survival Caspase cascade
    Apoptosis and survival Caspase cascade0.44
    Caspase cascade in apoptosis0.42
    FAS pathway and Stress induction of HSP regulation0.44
    4IL-9 Signaling Pathways
    Immune response IL 9 signaling pathway0.42
    Adipocytokines and Insulin Signaling0.34
    IL-9 Pathway0.36
    5PEDF Induced Signaling
    MIF Regulation of Innate Immune Cells0.94
    IL-6 Pathway0.61
    MIF Mediated Glucocorticoid Regulation0.94
    STAT3 Pathway0.47
    PEDF Induced Signaling0.73
    Endothelin-1 Signaling Pathway0.46
    all-trans-Retinoic Acid Signaling in Brain0.71
    Cytokine-cytokine receptor interaction0.43

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected R&D Systems Pathways for TNF (see all 8)
        NOD-like Receptor Signaling Pathways
    TNF Superfamily - Human Ligand-Receptor Interactions & their Associated Functions
    Adipocytokines & Insulin Signaling
    Th1 Differentiation
    Toll-Like receptor Signaling Pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for TNF (see all 50)
        Caspase Cascade
    THC Differentiation Pathway
    14-3-3 Induced Apoptosis
    Molecular Mechanisms of Cancer
    Antioxidant Action of Vitamin-C

    1 Cell Signaling Technology (CST) Pathway for TNF
        NF-kappaB Signaling

    Selected GeneGo (Thomson Reuters) Pathways for TNF (see all 15)
        Apoptosis and survival Anti-apoptotic TNFs/NF-kB/IAP pathway
    Immune response MIF-mediated glucocorticoid regulation
    Apoptosis and survival Caspase cascade
    Immune response MIF in innate immunity response
    Immune response IL-9 signaling pathway

    Selected BioSystems Pathways for TNF (see all 38)
        MAPK signaling pathway
    MicroRNAs in cardiomyocyte hypertrophy
    Apoptosis
    Cytokines and Inflammatory Response
    TGF Beta Signaling Pathway

    3 Sino Biological Pathways for TNF
        TNF Signaling
    Death Receptor Signaling
    NF-kB (NFkB) Pathway

    2 Reactome Pathways for TNF
        Transcriptional regulation of white adipocyte differentiation
    TNF signaling


    Selected Kegg Pathways  (Kegg details for TNF) (see all 45):
        MAPK signaling pathway
    Cytokine-cytokine receptor interaction
    NF-kappa B signaling pathway
    mTOR signaling pathway
    Apoptosis


    TNF for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Arrays including TNF (see all 50): 
              Lung Cancer in human mouse rat
              Antiviral Response in human mouse rat
              Multiple Sclerosis in human mouse rat
              Wound Healing in human mouse rat
              Lymphoma in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for TNF

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TNF (P013751, 2, 3 ENSP000003986984) via UniProtKB, MINT, STRING, and/or I2D (see all 154)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TNFRSF1AP194381, 2, 3, ENSP000001627494EBI-359977,EBI-299451 MINT-48045 MINT-49295 I2D: score=12 STRING: ENSP00000162749
    IKBKGQ9Y6K91, 2, 3EBI-359977,EBI-81279 MINT-8410390 I2D: score=1 
    RBCK1Q9BYM82, 3MINT-8410390 I2D: score=1 
    RNF31Q96EP02, 3MINT-8410390 I2D: score=1 
    TNFAIP3P215802, 3MINT-8410390 I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 128):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000060protein import into nucleus, translocation IDA16280327
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IDA15345745
    GO:0000165MAPK cascade IMP--
    GO:0000185activation of MAPKKK activity IDA15310755
    GO:0000187activation of MAPK activity IDA10748004

    TNF for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Enzo Life Sciences drugs & compounds for TNF
    3 ApexBio Compounds for TNF     About this table
    CompoundAction CAS #
    Lenalidomide (CC-5013)TNF-alfa secretion inhibitor with IC50 of 13 nM[191732-72-6]
    Necrostatin-1Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-alfa-induced necroptosis with EC50 of 490 nM[4311-88-0]
    Pomalidomide (CC-4047)Pomalidomide, previously known as CC-4047 or actimid, is a potent immunomodulatory molecule that exhibits antineoplastic activity for the treatment of hematological malignancies, especially relapsed and refractory multiple myeloma (MM)[19171-19-8]

    Compounds for TNF available from Tocris Bioscience    About this table
    CompoundAction CAS #
    SC 514IKKbeta inhibitor; attenuates NF-kappaB-induced gene expression[354812-17-2]
    Ro 106-9920Inhibitor of NF-kappaB activation[62645-28-7]
    IMD 0354Inhibitor of IKKbeta[978-62-1]
    CelastrolInhibits TNF-alpha-induced NF-kappaB activation[34157-83-0]
    Bay 11-7085Irreversible inhibitor of TNF-alpha-induced IkappaBalpha phosphorylation[196309-76-9]

    4 HMDB Compounds for TNF    About this table
    CompoundSynonyms CAS #PubMed Ids
    Butyric acid1-Butyrate (see all 25)107-92-616142751
    AtorvastatinAtorvastatin acid (see all 4)134523-00-5--
    Glucosamine2-Amino-2-deoxy-D-glucopyranose (see all 10)3416-24-8--
    Simvastatin(+)-Simvastatin (see all 28)79902-63-9--

    Selected DrugBank Compounds for TNF (see all 12)    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Infliximab-- 170277-31-3targetinhibitor15691299 16622728 11752352 15691217 12110154 17642244 15481318 16052578 16456024 15674127 15804598
    Adalimumab-- 331731-18-1targetantibody11752352 15200343 12044041 14532145 15022409 15046527
    EtanerceptCD120b (see all 7)185243-69-0targetantibody10375846 10206649 10405518 10338381 11752352 10357816
    Thalidomidealpha-phthalimidoglutarimide (see all 5)50-35-1targetinhibitor12167383 12105857 12046682 12113124 11752352 12102294
    AmrinoneAmrinona [inn-spanish] (see all 4)60719-84-8targetinhibitor1611705 10444479 10075051 11805217 11969359
    ChloroquineChloraquine (see all 6)54-05-7target--16418198 16761500 17456179 16870179 16670522
    Clenbuterol-- 37148-27-9targetother/unknown10071758 15021963 17139543 16261833 11193379
    Glucosamine-- 3416-24-8target--16431966 16469053 16445576 12244074 15930455
    Pranlukast-- 103177-37-3targetother/unknown17430359 12801315 12801316
    Certolizumab pegol-- 428863-50-7targetneutralizer23620660

    Selected Novoseek inferred chemical compound relationships for TNF gene (see all 141)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    infliximab 92.6 1681 16095114 (7), 11961039 (7), 12632433 (7), 15538942 (6) (see all 99)
    etanercept 92 1158 11961039 (8), 19188093 (5), 15005015 (5), 20443835 (5) (see all 99)
    adalimumab 89.5 487 11730333 (10), 19188093 (4), 17343250 (3), 17502862 (3) (see all 99)
    endotoxin 87.3 2305 8687293 (8), 1643887 (7), 9185243 (7), 1770269 (7) (see all 99)
    rantes 83.7 975 16466762 (6), 12663241 (6), 9527395 (6), 12388374 (5) (see all 99)
    pge2 79.9 2340 9298541 (9), 8388910 (8), 1836009 (8), 2378446 (7) (see all 99)
    il 10 79.5 347 19771178 (7), 11166831 (5), 15800006 (5), 12719394 (5) (see all 99)
    pentoxifylline 78.4 990 8189599 (9), 1385797 (8), 7589090 (7), 9486396 (6) (see all 99)
    nitric oxide 76.3 4152 7706743 (11), 8046239 (9), 11566624 (9), 1517576 (8) (see all 99)
    abatacept 74.2 77 19916731 (4), 18590608 (4), 17057043 (3), 18670735 (3) (see all 42)

    5 PharmGKB related drug/compound annotations for TNF gene    About this table
    Drug/compound PharmGKB Annotation
    abacavirCA  
    adalimumabCA  
    carbamazepineCA  
    etanerceptCA  
    infliximabCA  



    TNF for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

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    REFSEQ mRNAs for TNF gene: 
    NM_000594.3  

    Unigene Cluster for TNF:

    Tumor necrosis factor
    Hs.241570  [show with all ESTs]
    Unigene Representative Sequence: NM_000594
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000449264(uc003nui.3 uc003nuj.3)
    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TNF using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TNF (see all 29):
    hsa-miR-549 hsa-miR-875-3p hsa-miR-181c hsa-miR-3141 hsa-miR-4263 hsa-miR-331-3p hsa-miR-301a hsa-miR-181a-2*
    SwitchGear 3'UTR luciferase reporter plasmidTNF 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TNF
    Predesigned siRNA for gene silencing in human, mouse, rat TNF
    Clone
    Products:
         
    OriGene clones in human, mouse for TNF (see all 6)
    OriGene ORF clones in mouse, rat for TNF
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TNF (NM_001192)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TNF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TNF
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TNF
    OriGene qSTAR qPCR primer pairs in human, mouse for TNF
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TNF
      QuantiTect SYBR Green Assays in human, mouse, rat TNF
      QuantiFast Probe-based Assays in human, mouse, rat TNF

    Additional mRNA sequence: 

    AB451492.1 AF043342.1 AF098751.1 AJ227911.1 AK314960.1 BC028148.1 FJ795028.1 HQ201306.2 
    M10988.1 X01394.1 

    6 DOTS entries:

    DT.447264  DT.75172441  DT.100717788  DT.121394302  DT.40132506  DT.95165288 

    Selected AceView cDNA sequences (see all 68):

    CA307225 BM831593 BM844832 CA310368 NM_000594 BM762686 BM842415 CD364761 
    BC028148 X01394 BG232086 M10988 BI910312 CA307429 CD367625 CD366187 
    CD368116 CA308256 CD368929 AI088239 BI908079 CD367794 CA748748 CD367664 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TNF expression in normal human tissues (normalized intensities)      TNF embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGCCCCCTG
    TNF Expression
    About this image


    TNF expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Blood (Cardiovascular System)    fully expand to see all 3 entries
             Kupffer Cells Sinusoids
             Angiogenic cell precursor
     
     Liver (Hepatobiliary System)
             Kupffer Cells Sinusoids
     
     Epithelial Cells
             Duct Cells Pancreatic Ducts
     
     NULL (Uncategorized)
             Adipose-derived stromal vascular fraction and adipocytes (HiQCell)
     
     Zygote (Early Embryonic Tissues)
             8-Cell Embryo Morula
    TNF Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TNF Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.241570
        Pathway & Disease-focused RT2 Profiler PCR Arrays including TNF (see all 50): 
              Lung Cancer in human mouse rat
              Antiviral Response in human mouse rat
              Multiple Sclerosis in human mouse rat
              Wound Healing in human mouse rat
              Lymphoma in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TNF
    OriGene qSTAR qPCR primer pairs in human, mouse for TNF
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TNF
    QuantiTect SYBR Green Assays in human, mouse, rat TNF
    QuantiFast Probe-based Assays in human, mouse, rat TNF
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNF

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TNF gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tnf1 , 5 tumor necrosis factor1, 5 82.9(n)1
    80.17(a)1
      17 (18.59 cM)5
    219261  NM_013693.31  NP_038721.11 
     351993815 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    38(a)
    37(a)
    1 ↔ many
    1 ↔ many
    2(195685950-195692186)
    2(195674701-195679824)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tnf1 tumor necrosis factor 50.43(n)
    34.36(a)
      100134991  NM_001113671.1  NP_001107143.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tnfa6
    tnfb6
    tumor necrosis factor a (TNF superfamily, member 2...
    tumor necrosis factor b (TNF superfamily, member 2...
    26(a)
    24(a)
    many ↔ many
    many ↔ many
    19(27505097-27509684) ENSDARG00000009511
    15(33995840-33998916) ENSDARG00000013598


    ENSEMBL Gene Tree for TNF (if available)
    TreeFam Gene Tree for TNF (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TNF gene
    FASLG2  TNFSF152  LTA2  TNFSF142  
    2 SIMAP similar genes for TNF using alignment to 4 protein entries:     TNFA_HUMAN (see all proteins):
    LTA    FASLG

    TNF for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Polymorphic Variants from UniProtKB/Swiss-Prot
    TNFA_HUMAN, P01375: Genetic variations in TNF influence susceptibility to hepatitis B virus (HBV) infection [MIM:610424]
    TNFA_HUMAN, P01375: Genetic variations in TNF are involved in susceptibility to malaria [MIM:611162]


    Selected SNPs for TNF (see all 131)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs18006301,2
    C,F,H--31459428(+) CCCCCC/ACTTAA 1 -- us2k135Minor allele frequency- A:0.14NS MN NA EA WA 4098
    rs46458361,2
    C,F--31459428(+) CCCCCC/ACTTAA 1 -- us2k11Minor allele frequency- A:0.15NS 158
    rs17997241,2
    C,F--31459434(+) CTTAAC/TGAAGA 1 -- us2k130Minor allele frequency- T:0.09NS MN NA EA WA 2962
    rs42481581,2
    C,F,H--31459485(+) AGGACC/TTCCAG 1 -- us2k17Minor allele frequency- T:0.01NS EA NA 808
    rs49870861,2
    C,F,H--31459509(+) GGGACG/ATTTAA 1 -- us2k19Minor allele frequency- A:0.00MN NS EA 804
    rs42481591,2
    C,F,H--31459532(+) ACACAC/ATGGGG 1 -- us2k16Minor allele frequency- A:0.00NS EA 740
    rs27361961,2
    C,H--31459607(-) ATGCTG/TGTTTC 1 -- us2k14Minor allele frequency- T:0.00NS EA 406
    rs27361951,2
    C--31459643(-) AGGCCC/TTCTTC 1 -- us2k10--------
    rs42481601,2
    C,F--31459645(+) AGAAGG/ACCTGC 1 -- us2k13Minor allele frequency- A:0.01NS NA 332
    rs42481611,2
    C,F--31459719(+) CTGCTA/CCCCCC 1 -- us2k14Minor allele frequency- C:0.02NS NA 334

    HapMap Linkage Disequilibrium report for TNF (31543344 - 31546113 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for TNF:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv830627CNV Loss17160897
    nsv462870CNV Loss19166990
    nsv470809CNV Loss18288195
    nsv884418CNV Gain21882294

    Human Gene Mutation Database (HGMD): TNF
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TNF
    DNA2.0 Custom Variant and Variant Library Synthesis for TNF

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 191160   
    OMIM disorders: 611162  600807  157300  
    UniProtKB/Swiss-Prot: TNFA_HUMAN, P01375
  • Psoriatic arthritis (PSORAS) [MIM:607507]: An inflammatory, seronegative arthritis associated with
    psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive,
    erosive arthropathy. Five types of psoriatic arthritis have been defined: asymmetrical oligoarthritis
    characterized by primary involvement of the small joints of the fingers or toes; asymmetrical arthritis which
    involves the joints of the extremities; symmetrical polyarthritis characterized by a rheumatoid like pattern that
    can involve hands, wrists, ankles, and feet; arthritis mutilans, which is a rare but deforming and destructive
    condition; arthritis of the sacroiliac joints and spine (psoriatic spondylitis). Note=Disease susceptibility is
    associated with variations affecting the gene represented in this entry

  • Selected diseases for TNF (see all 757):    About MalaCards
    aphthous stomatitis    vascular dementia    migraine without aura    septic shock
    magic syndrome    mycobacterium chelonae    meliodosis    periodic fever, aphthous stomatitis, pharyngitis and adenitis
    new daily-persistent headache    stomatitis    uveitis    cerebral malaria
    toxic shock syndrome    tuberculoid leprosy    mucocutaneous leishmaniasis    visual agnosia
    tuberculous uveitis    adult pulmonary langerhans cell histiocytosis    central nervous system vasculitis    punctate inner choroidopathy

    Selected diseases from the University of Copenhagen DISEASES database for TNF (see all 24):
    Rheumatoid arthritis     Crohn's disease     Cancer     Hypersensitivity reaction type II disease
    Vascular disease     Malaria     Psoriasis     Psoriatic arthritis
    Connective tissue disease     Tuberculosis     Ankylosing spondylitis     Asthma
    Multiple sclerosis     Peritonitis     Diabetes mellitus     Liver disease
    Pneumonia     Ulcerative colitis     Uveitis     Kidney disease

    TNF for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Selected Novoseek inferred disease relationships for TNF gene (see all 96)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    necrosis 99 80542 15626980 (12), 1595815 (11), 2374209 (11), 10561634 (10) (see all 99)
    tumors 96.4 68579 15626980 (12), 1595815 (11), 2374209 (11), 10561634 (10) (see all 99)
    inflammation 92.2 3272 17482668 (5), 20439544 (5), 7737534 (4), 9042105 (4) (see all 99)
    rheumatoid arthritis 90.1 2641 1802490 (5), 15879156 (4), 8329189 (4), 19560810 (4) (see all 99)
    arthritis psoriatic 79 279 16284098 (4), 9326391 (4), 15838232 (3), 14678719 (3) (see all 99)
    sepsis 78.9 1166 1860332 (7), 15526005 (6), 2064171 (5), 8403981 (5) (see all 99)
    tumor necrosis factor receptor-associated periodic syndrome 78.8 119 12352631 (2), 15689926 (2), 18347298 (2), 15492850 (2) (see all 82)
    spondylitis ankylosing 77.7 312 9704649 (4), 15838232 (3), 17414952 (3), 16763453 (3) (see all 99)
    shock septic 77.7 621 9366763 (8), 2285204 (5), 8318801 (5), 10966243 (4) (see all 99)
    arthritis 77.5 684 8033415 (5), 9585810 (5), 7589090 (5), 8222316 (4) (see all 99)

    Genetic Association Database (GAD): TNF
    Human Genome Epidemiology (HuGE) Navigator: TNF (2475 documents)
    Tumor Gene Database (TGDB): TNF

    Export disorders for TNF gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TNF gene, integrated from 10 sources (see all 17174) (see top 10):
    (articles sorted by number of sources associating them with TNF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria. (PubMed id 10369255)1, 2, 4, 9 Knight J.C.... Kwiatkowski D. (Nat. Genet. 1999)
    2. Association of TNF-alpha promoter polymorphisms with the clearance of hepatitis B virus infection. (PubMed id 12915457)1, 2, 4 Kim Y.J.... Shin H.D. (Hum. Mol. Genet. 2003)
    3. Cytokine gene polymorphisms: association with psoriatic arthritis susceptibility and severity. (PubMed id 12746914)1, 2, 4 Balding J.... FitzGerald O. (Arthritis Rheum. 2003)
    4. Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. (PubMed id 6392892)1, 2, 3 Pennica D.... Goeddel D.V. (Nature 1984)
    5. The tumor necrosis factor polymorphism TNF (-308) is associated with susceptibility to meningococcal sepsis, but not with lethality. (PubMed id 19242354)1, 4, 9 Read R.C....Wilson A.G. (Crit. Care Med. 2009)
    6. Association between the level of circulating bioactive tumor necrosis factor alpha and the tumor necrosis factor alpha gene polymorphism at -308 in patients with rheumatoid arthritis treated with a tumor necrosis factor alpha inhibitor. (PubMed id 18438841)1, 4, 9 Marotte H....Miossec P. (Arthritis Rheum. 2008)
    7. TNF polymorphism and bronchoalveolar lavage cell TNF-alpha levels in chronic beryllium disease and beryllium sensitization. (PubMed id 17208287)1, 4, 9 Sato H....Maier L.A. (J. Allergy Clin. Immunol. 2007)
    8. TNF-alpha gene promoter polymorphism at nucleotide -308 and the inflammatory response and oxidative stress induced by cardiac surgery: role of heart failure and medical treatment. (PubMed id 18450464)1, 4, 9 GaliA+anes M....Hadjinikolaou L. (Eur J Cardiothorac Surg 2008)
    9. TNFalpha genotype affects TNFalpha release, insulin sensitivity and the severity of liver disease in HCV chronic hepatitis. (PubMed id 16143422)1, 4, 9 Valenti L....Fargion S. (J. Hepatol. 2005)
    10. Association of bladder tumors and GA genotype of -308 nucleotide in tumor necrosis factor-alpha promoter with greater tumor necrosis factor-alpha expression. (PubMed id 15533517)1, 4, 9 Jeong P....Kim W.J. (Urology 2004)
    11. TNF-alpha promoter, Nod2 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin. (PubMed id 15016407)1, 4, 9 Schippers E.F....van Dissel J.T. (Cytokine 2004)
    12. Tumor necrosis factor-alpha -308G/A single nucleotide polymorphism and red-complex periodontopathogens are independently associated with increased levels of tumor necrosis factor-alpha in diseased periodontal tissues. (PubMed id 19076989)1, 4, 9 Trombone A.P....Garlet G.P. (J. Periodont. Res. 2009)
    13. TNFA and IL10 gene polymorphisms are not associated with periodontitis in Brazilians. (PubMed id 19771178)1, 4, 9 Moreira P.R....Dutra W.O. (Open Dent J 2009)
    14. Single nucleotide polymorphisms in TNF-alpha, TNFR2 gene and TNF-alpha production in Asian Indians. (PubMed id 19811435)1, 4, 9 Gupta R....Das S.N. (Immunol. Invest. 2009)
    15. TNF and TNFR polymorphisms in severe sepsis and septic shock: a prospective multicentre study. (PubMed id 15526005)1, 4, 9 Gordon A.C....Hinds C.J. (Genes Immun. 2004)
    16. TNF-alpha and TGF-beta1 gene polymorphisms and renal allograft rejection in Koreans. (PubMed id 15546338)1, 4, 9 Park J.Y....Ahn C. (Tissue Antigens 2004)
    17. Cytokine gene polymorphisms in hemodialysis patients: association with comorbidity, functionality, and serum albumin. (PubMed id 15086488)1, 4, 9 Balakrishnan V.S....Pereira B.J. (Kidney Int. 2004)
    18. Tumor necrosis factor alpha promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease. (PubMed id 11832442)1, 4, 9 Valenti L....Fargion S. (Gastroenterology 2002)
    19. Tumor necrosis factor alpha (-308), interleukin-6 (-174) and interleukin-10 (-1082) gene polymorphisms in polycystic ovary syndrome. (PubMed id 20189706)1, 4, 9 Vural P....AkgA1l C. (Eur. J. Obstet. Gynecol. Reprod. Biol. 2010)
    20. Association of TNF-alpha with severe respiratory syncytial virus infection and bronchial asthma. (PubMed id 18811622)1, 4, 9 Puthothu B....Heinzmann A. (Pediatr Allergy Immunol 2009)
    21. Association of TNF polymorphisms with sarcoidosis, its prognosis and tumour necrosis factor (TNF)-alpha levels in Asian Indians. (PubMed id 18062795)1, 4, 9 Sharma S....Sharma S.K. (Clin. Exp. Immunol. 2008)
    22. TNF-alpha (-308 G/A) and CD14 (-159T/C) polymorphisms in the bronchial responsiveness of Korean children with asthma. (PubMed id 17196641)1, 4, 9 Hong S.J....Park C.S. (J. Allergy Clin. Immunol. 2007)
    23. NRAMP1 and TNF-alpha polymorphisms and susceptibility to tuberculosis in Thais. (PubMed id 17298451)1, 4, 9 Vejbaesya S....Sermduangprateep C. (Respirology 2007)
    24. Differential effect of IL10 and TNF{alpha} genotypes on determining susceptibility to discoid and systemic lupus erythematosus. (PubMed id 15800006)1, 4, 9 SuA!rez A....GutiAcrrez C. (Ann. Rheum. Dis. 2005)
    25. Association of TNF-alpha and TNF-beta gene polymorphism with steroid receptor expression in breast cancer patients. (PubMed id 15999154)1, 4, 9 Kamali-Sarvestani E....Talei A.A. (Pathol. Oncol. Res. 2005)
    26. Relation of tumor necrosis factor (TNF) gene polymorphisms with serum concentrations and in vitro production of TNF-alpha and interleukin-8 in heavy drinkers. (PubMed id 15902922)1, 4, 9 GonzA!lez-Quintela A....Perez L.F. (Alcohol 2004)
    27. Tumour necrosis factor-alpha gene promoter region -308 and -376 G--&gt;A polymorphisms in BehAset's disease. (PubMed id 14727453)1, 4, 9 Duymaz-Tozkir J....Saruhan-Direskeneli G. (Clin. Exp. Rheumatol. 2003)
    28. Lack of association of TNF-238A and -308A in Japanese patients with psoriasis vulgaris, psoriatic arthritis and generalized pustular psoriasis. (PubMed id 12234707)1, 4, 9 Nishibu A....Kaneko F. (J. Dermatol. Sci. 2002)
    29. Recurrent miscarriage and variant alleles of mannose binding lectin, tumour necrosis factor and lymphotoxin alpha genes. (PubMed id 11737072)1, 4, 9 Baxter N....Summerfield J.A. (Clin. Exp. Immunol. 2001)
    30. Genetic variation in the stress protein hsp70-2 gene is highly associated with obesity. (PubMed id 11319647)1, 4, 9 Chouchane L....Strosberg A.D. (Int. J. Obes. Relat. Metab. Disord. 2001)
    31. Interleukin-6 (G-174C) and tumour necrosis factor-alpha (G-308A) gene polymorphisms in geriatric patients with chronic periodontitis. (PubMed id 19555357)1, 4, 9 Costa A.M....Bezerra A.C. (Gerodontology 2010)
    32. [TNF alfa polymorphism and course of ulcerative colitis]. (PubMed id 19606693)1, 4, 9 JaA8ocha A.8....Fiedorowicz E. (Pol. Merkur. Lekarski 2009)
    33. Influence of cytokine gene polymorphisms on IgA nephropathy. (PubMed id 18300111)1, 4, 9 Bantis C....Ivens K. (Ren Fail 2008)
    34. Sepsis syndrome and death in trauma patients are associated with variation in the gene encoding tumor necrosis factor. (PubMed id 18434886)1, 4, 9 Menges T....Bein G. (Crit. Care Med. 2008)
    35. Genetic polymorphisms of adiponectin and tumor necrosis factor-alpha and nonalcoholic fatty liver disease in Chinese people. (PubMed id 18565022)1, 4, 9 Wong V.W....Chan H.L. (J. Gastroenterol. Hepatol. 2008)
    36. Association between LTA, TNF and AGER polymorphisms and late diabetic complications. (PubMed id 18575614)1, 4, 9 Lindholm E....Agardh C.D. (PLoS ONE 2008)
    37. Characterization of tumour necrosis factor-alpha genetic variants and mRNA expression in patients with severe sepsis. (PubMed id 18643840)1, 4, 9 O'Dwyer M.J....Ryan T. (Int. J. Immunogenet. 2008)
    38. Effect of the 252A&gt;G polymorphism of the lymphotoxin-alpha gene on inflammatory markers of response to cigarette smoking in Korean healthy men. (PubMed id 17113059)1, 4, 9 Jang Y....Lee J.H. ( international journal of clinical chemistry 2007)
    39. Tumour necrosis factor alpha promoter polymorphisms and etanercept therapy in juvenile idiopathic arthritis. (PubMed id 16951943)1, 4, 9 Schmeling H. and Horneff G. (Rheumatol. Int. 2007)
    40. Influence of TNF gene polymorphisms in Japanese patients with NASH and simple steatosis. (PubMed id 17395331)1, 4, 9 Tokushige K....Shiratori K. (J. Hepatol. 2007)
    41. Common TNF-alpha, IL-1 beta, PAI-1, uPA, CD14 and TLR4 polymorphisms are not associated with disease severity or outcome from Gram negative sepsis. (PubMed id 17877801)1, 4, 9 Jessen K.M....Benfield T. (BMC Infect. Dis. 2007)
    42. Tumor necrosis factor-alpha and interleukin-4 gene polymorphisms in Chinese patients with gout. (PubMed id 17631734)1, 4, 9 Chen M.L....Huang C.M. (Clin. Exp. Rheumatol. 2007)
    43. A - 308 promoter polymorphism of tumor necrosis factor alpha gene does not associate with the susceptibility to psoriasis vulgaris. No difference either between psoriasis type I and type II patients. (PubMed id 17053845)1, 4, 9 Baran W....Baran E. (Acta Dermatovenerol Alp Panonica Adriat 2006)
    44. TNFalpha polymorphisms and risk of psoriatic arthritis. (PubMed id 16284098)1, 4, 9 Rahman P....Gladman D. (Ann. Rheum. Dis. 2006)
    45. Polymorphism of cytokine genes (TGF-beta1, IFN-gamma, IL-6, IL-10, and TNF-alpha) in patients with chronic pancreatitis. (PubMed id 15841043)1, 4, 9 Bendicho M.T....Lemaire D.C. (Pancreas 2005)
    46. -238 and +489 TNF-alpha along with TNF-RII gene polymorphisms associate with the diffuse phenotype in patients with Systemic Sclerosis. (PubMed id 15585313)1, 4, 9 Tolusso B....Ferraccioli G. (Immunol. Lett. 2005)
    47. [The associations of the single nucleotide polymorphisms on TNF and CD14 promoters with the mortality of infection, systematic inflammatory response syndromec and sepsis in surgical patients]. (PubMed id 14720421)1, 4, 9 Yu B.J....Tang X.M. (Zhonghua Yi Xue Za Zhi 2003)
    48. Polymorphisms in the +252(A/G) lymphotoxin-alpha and the -308(A/G) tumor necrosis factor-alpha genes and susceptibility to chronic periodontitis in a Czech population. (PubMed id 12828656)1, 4, 9 Fassmann A....Vanek J. (J. Periodont. Res. 2003)
    49. Association of plasma levels of tumor necrosis factor (TNF)-alpha and its soluble receptors, two polymorphisms of the TNF gene, with acute severe pancreatitis and early septic shock due to it. (PubMed id 12717265)1, 4, 9 Dianliang Z....Baojun Y. (Pancreas 2003)
    50. TNF-alpha and TNF-beta gene polymorphisms in cerebral infarction. (PubMed id 14593215)1, 4, 9 Um J.Y....Kim H.M. (J. Mol. Neurosci. 2003)
    51. Polymorphisms in TNFA and TNFR2 affect outcome of unrelated bone marrow transplantation. (PubMed id 11979305)1, 4, 9 Ishikawa Y....Juji T. (Bone Marrow Transplant. 2002)
    52. Polymorphisms of the tumor necrosis factor-alpha gene promoter predict for outcome after thalidomide therapy in relapsed and refractory multiple myeloma. (PubMed id 12200397)1, 4, 9 Neben K....Goldschmidt H. (Blood 2002)
    53. TNF and LTA gene polymorphisms reveal different risk in gastric and duodenal ulcer patients. (PubMed id 11781708)1, 4, 9 Lanas A....PeA+a A.S. (Genes Immun. 2001)
    54. Association between polymorphisms in human tumor necrosis factor-alpha (--308) and -beta (252) genes and development of gestational diabetes mellitus. (PubMed id 20189261)1, 4, 9 Montazeri S....Radhakrishnan A.K. (Diabetes Res. Clin. Pract. 2010)
    55. Genetic variation in chromosomal translocation breakpoint and immune function genes and risk of non-Hodgkin lymphoma. (PubMed id 20087644)1, 4, 9 Fernberg P....EkstrAPm Smedby K. (amp 2010)
    56. Genetic association of Toll-like-receptor 4 and tumor necrosis factor-alpha polymorphisms with Plasmodium falciparum blood infection levels. (PubMed id 20307689)1, 4, 9 Basu M....Sengupta S. (Infect. Genet. Evol. 2010)
    57. The NRAMPI, VDR and TNF-alpha gene polymorphisms in Iranian tuberculosis patients: the study on host susceptibility. (PubMed id 20231985)1, 4, 9 Merza M....Hoffner S. (Braz J Infect Dis 2009)
    58. Variation in the lymphotoxin-alpha/tumor necrosis factor locus modifies risk of erythema nodosum in sarcoidosis. (PubMed id 19225544)1, 4, 9 McDougal K.E....Cutting G.R. (J. Invest. Dermatol. 2009)
    59. The role of tumor necrosis factor (TNF)-alpha and TNF receptor polymorphisms in susceptibility to ankylosing spondylitis. (PubMed id 19772798)1, 4, 9 Chatzikyriakidou A....Drosos A.A. (Clin. Exp. Rheumatol. 2009)
    60. Association of polymorphisms in Tumor Necrosis Factor Alpha and Beta genes with increased risk for oral cancer. (PubMed id 19528505)1, 4, 9 Yapijakis C....Vairaktaris E. (Anticancer Res. 2009)
    61. Long-range linkage on chromosome 6p of VEGF, FKBP5, HLA and TNF alleles associated with transplant rejection. (PubMed id 19233472)1, 4, 9 Chen Y....Hutchinson I.V. (Mol. Immunol. 2009)
    62. [Relationship among TNF-alpha gene promoter -308 site polymorphism, the levels of maternal serum TNF-alpha, and the mRNA expression placental TNF-alpha in preterm labor]. (PubMed id 19292050)1, 4, 9 Pu J. and Zeng W.Y. (Sichuan Da Xue Xue Bao Yi Xue Ban 2009)
    63. [Effect of TNF-alpha gene polymorphism on outcome of thalidomide-based regimens for multiple myeloma]. (PubMed id 19954656)1, 4, 9 DU J....Hou J. (Zhonghua Xue Ye Xue Za Zhi 2009)
    64. Association of gastric disease with polymorphisms in the inflammatory-related genes IL-1B, IL-1RN, IL-10, TNF and TLR4. (PubMed id 19295440)1, 4, 9 Murphy G....O'Sullivan M. (amp 2009)
    65. Tumor necrosis factor gene polymorphisms in Turkish patients with sarcoidosis. (PubMed id 18451575)1, 4, 9 Seyhan E.C....Issever H. (Intern. Med. 2008)
    66. Influence of functional interleukin 10/tumor necrosis factor-alpha polymorphisms on interferon-alpha, IL-10, and regulatory T cell population in patients with systemic lupus erythematosus receiving antimalarial treatment. (PubMed id 18597405)1, 4, 9 LA^pez P....SuA!rez A. (J. Rheumatol. 2008)
    67. Cytokine gene polymorphism in kidney transplantation--impact of TGF-beta 1, TNF-alpha and IL-6 on graft outcome. (PubMed id 18158121)1, 4, 9 Nikolova P.N....Naumova E.J. (Transpl. Immunol. 2008)
    68. Combined effect of tumour necrosis factor-alpha and interleukin-13 polymorphisms on bronchial hyperresponsiveness in Korean children with asthma. (PubMed id 18341619)1, 4, 9 Kim H.B....Hong S.J. (Clin. Exp. Allergy 2008)
    69. A single tumour necrosis factor haplotype influences the response to adalimumab in rheumatoid arthritis. (PubMed id 17673491)1, 4, 9 Miceli-Richard C....Mariette X. (Ann. Rheum. Dis. 2008)
    70. Polymorphisms of tumor-necrosis factor-alpha - 308 and lymphotoxin-alpha + 250: possible modulation of susceptibility to apoptosis in chronic lymphocytic leukemia and non-Hodgkin lymphoma mononuclear cells. (PubMed id 19021060)1, 4, 9 Jevtovic-Stoimenov T....PavloviA8 S. (amp 2008)
    71. Associations between tumor necrosis factor-alpha and lymphotoxin-alpha polymorphisms and idiopathic recurrent miscarriage. (PubMed id 18299433)1, 4, 9 Zammiti W....Mahjoub T. (Reproduction 2008)
    72. Tumor necrosis factor-alpha and interleukin-10 gene promoter polymorphisms in Turkish rheumatoid arthritis patients. (PubMed id 18427872)1, 4, 9 Ates O....Topal-Sarikaya A. (Clin. Rheumatol. 2008)
    73. Tumor necrosis factor--alpha and transforming growth factor--beta1 polymorphisms in bronchial asthma. (PubMed id 18711258)1, 4, 9 Kumar A....Sehajpal P.K. (Indian J Med Sci 2008)
    74. TNFalpha in patients with end-stage heart failure on medical therapy or supported by a left ventricular assist device. (PubMed id 18346639)1, 4, 9 Bruggink A.H....De Weger R.A. (Transpl. Immunol. 2008)
    75. [Association between susceptibility of endometriosis and the gene polymorphism of tumor necrosis factor]. (PubMed id 18754435)1, 4, 9 Lu D.H....Deng L. (Zhonghua Yi Xue Za Zhi 2008)
    76. [Influence of G308A polymorphism of tumor necrosis factor alpha gene on insulin resistance in obese patients after weight loss]. (PubMed id 17927932)1, 4, 9 de Luis D.A....Romero E. (Med Clin (Barc) 2007)
    77. Polymorphisms in TGFbeta and TNFalpha are associated with the myelodysplastic syndrome phenotype. (PubMed id 18081437)1, 4, 9 Powers M.P....Chang C.C. (amp 2007)
    78. Effect of tumor necrosis factor-alpha gene polymorphism on peri-implant bone loss following prosthetic reconstruction. (PubMed id 17356374)1, 4, 9 Cury P.R....de AraA_jo N.S. (Implant Dent 2007)
    79. Role of IL-6, TNF-A and LT-A variants in the modulation of the clinical expression of plaque-induced gingivitis. (PubMed id 17953695)1, 4, 9 Scapoli C....Trombelli L. (J. Clin. Periodontol. 2007)
    80. Association of TGFbeta1, TNFalpha, CCR2 and CCR5 gene polymorphisms in type-2 diabetes and renal insufficiency among Asian Indians. (PubMed id 17428349)1, 4, 9 Prasad P....Thelma B.K. (BMC Med. Genet. 2007)
    81. Clinical and genetic risk factors for pneumonia in systemic lupus erythematosus. (PubMed id 17665457)1, 4, 9 Kinder B.W....Criswell L.A. (Arthritis Rheum. 2007)
    82. TNF-alpha gene promoter -238G&gt;A and -308G&gt;A polymorphisms alter risk of psoriasis vulgaris: a meta-analysis. (PubMed id 17446901)1, 4, 9 Li C....Gao T. (J. Invest. Dermatol. 2007)
    83. Associations of promoter region polymorphisms in the tumour necrosis factor-alpha gene and early-onset psoriasis vulgaris in a northern Polish population. (PubMed id 17553030)1, 4, 9 Nedoszytko B....Roszkiewicz J. (Br. J. Dermatol. 2007)
    84. Predictive value of cytokine gene polymorphisms for the development of end-stage renal disease. (PubMed id 17173255)1, 4, 9 Babel N....Reinke P. (J. Nephrol. 2006)
    85. Cytokine gene polymorphisms in Turkish patients with inflammatory bowel disease. (PubMed id 16638698)1, 4, 9 Celik Y....Bozdayi A.M. (Scand. J. Gastroenterol. 2006)
    86. Polymorphisms in the TNF-alpha promoter and variability in the granulomatous response in patients with Crohn's disease. (PubMed id 16641217)1, 4, 9 Dalal I....Levine A. (Pediatr. Res. 2006)
    87. MHC class II, tumour necrosis factor alpha, and lymphotoxin alpha gene haplotype associations with serological subsets of systemic lupus erythematosus. (PubMed id 16107511)1, 4, 9 McHugh N.J....Welsh K. (Ann. Rheum. Dis. 2006)
    88. Association of TNF haplotypes with asthma, serum IgE levels, and correlation with serum TNF-alpha levels. (PubMed id 16728705)1, 4, 9 Sharma S....Ghosh B. (Am. J. Respir. Cell Mol. Biol. 2006)
    89. Combined polymorphisms of tumour necrosis factor alpha and interleukin-10 genes in patients with alcoholic hepatitis. (PubMed id 16702858)1, 4, 9 Richardet J.P....Bories P.N. (amp 2006)
    90. Prevalence of two tumor necrosis factor gene polymorphisms in premature infants with early onset sepsis. (PubMed id 17108674)1, 4, 9 Schueller A.C....Stuber F. (Biol. Neonate 2006)
    91. Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph Consortium. (PubMed id 16389181)1, 4, 9 Rothman N....Nieters A. (Lancet Oncol. 2006)
    92. Tumour necrosis factor (TNF)alpha -308 G/G promoter polymorphism and TNFalpha levels correlate with a better response to adalimumab in patients with rheumatoid arthritis. (PubMed id 17343250)1, 4, 9 Cuchacovich M....AguillA^n J.C. (Scand. J. Rheumatol. 2006)
    93. Genetic contribution of the tumour necrosis factor (TNF) B + 252*2/2 genotype, but not the TNFa,b microsatellite alleles, to systemic lupus erythematosus in Japanese patients. (PubMed id 15932622)1, 4, 9 Takeuchi F....Tanimoto K. (Int. J. Immunogenet. 2005)
    94. Extended haplotype in the tumor necrosis factor gene cluster is associated with asthma and asthma-related phenotypes. (PubMed id 15976383)1, 4, 9 Randolph A.G....Weiss S.T. (Am. J. Respir. Crit. Care Med. 2005)
    95. Association between TNF-alpha and TGF-beta genotypes in infants and parental history of allergic rhinitis and asthma. (PubMed id 15120189)1, 4, 9 Gentile D.A....Skoner D.P. (Hum. Immunol. 2004)
    96. Susceptibility for ischemic stroke in Korean population is associated with polymorphisms of the interleukin-1 receptor antagonist and tumor necrosis factor-alpha genes, but not the interleukin-1beta gene. (PubMed id 15036607)1, 4, 9 Lee B.C....Chung J.H. (Neurosci. Lett. 2004)
    97. [Potential effect of tumor necrosis factor-alpha and tumor necrosis factor receptor II gene polymorphisms on the pathogenesis of silicosis]. (PubMed id 15555301)1, 4, 9 Li L....Liu B.C. (Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2004)
    98. Tumour necrosis factor alpha polymorphisms are not involved in the development of steatosis in chronic hepatitis C. (PubMed id 15256977)1, 4, 9 SA!nchez-MuA+oz D....NuA+ez-Roldan A. (amp 2004)
    99. Polymorphisms in the tumor necrosis factor-alpha gene at position -308 and the inducible 70 kd heat shock protein gene at position +1267 in multifetal pregnancies and preterm premature rupture of fetal membranes. (PubMed id 15507967)1, 4, 9 Kalish R.B....Witkin S.S. (Am. J. Obstet. Gynecol. 2004)
    100. Polymorphism in promoter region of IL10 gene is associated with rheumatoid arthritis in women. (PubMed id 14994383)1, 4, 9 Padyukov L....Klareskog L. (J. Rheumatol. 2004)
    101. [Potential effect of tumor necrosis factor-alpha and its receptor II gene polymorphisms on the pathogenesis of coal worker's pneumoconiosis]. (PubMed id 15355698)1, 4, 9 Li L....Wang H.L. (Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2004)
    102. Association of tumor necrosis factor polymorphisms with asthma and serum total IgE. (PubMed id 14681301)1, 4, 9 Shin H.D....Park C.S. (Hum. Mol. Genet. 2004)
    103. Tumor necrosis factor-alpha allele lymphotoxin-alpha+250 is associated with the presence and severity of placental inflammation among preterm births. (PubMed id 15128916)1, 4, 9 Kazzi S.N....Buhimschi I.A. (Pediatr. Res. 2004)
    104. Association of IL-1beta, IL-1ra, and TNF-alpha gene polymorphisms in childhood nephrotic syndrome. (PubMed id 14758530)1, 4, 9 Kim S.D....Cho B.S. (Pediatr. Nephrol. 2004)
    105. Polymorphisms within the tumor necrosis factor and lymphotoxin-alpha genes and endemic pemphigus foliaceus--are there any associations? (PubMed id 14617046)1, 4, 9 Roxo V.M....Petzl-Erler M.L. (Tissue Antigens 2003)
    106. Cytokine single nucleotide polymorphisms and intrarenal gene expression in chronic allograft nephropathy in children. (PubMed id 12787424)1, 4, 9 Melk A....Von Schnakenburg C. (Kidney Int. 2003)
    107. Lack of association between the promoter polymorphisms at positions -308 and -238 of the tumor necrosis factor alpha gene and psoriasis vulgaris in Japanese patients. (PubMed id 14657629)1, 4, 9 Tsunemi Y....Tamaki K. (Dermatology (Basel) 2003)
    108. Tumor necrosis factor-alpha, lymphotoxin-alpha, and interleukin-10 gene polymorphisms and restenosis after coronary artery stenting. (PubMed id 14572794)1, 4, 9 Koch W....Kastrati A. (Cytokine 2003)
    109. TNF and TNF receptor polymorphisms in Korean Behcet's disease patients. (PubMed id 12770792)1, 4, 9 Lee E.B....Song Y.W. (Hum. Immunol. 2003)
    110. Relation between tumour necrosis factor polymorphism TNFalpha-308 and risk of asthma. (PubMed id 11896460)1, 4, 9 Witte J.S....Hall J.M. (Eur. J. Hum. Genet. 2002)
    111. TNF-alpha and -beta gene polymorphisms in multiple sclerosis: a highly significant role for determinants in the first intron of the TNF-beta gene. (PubMed id 12568117)1, 4, 9 Fernandes Filho J.A....Pandey J.P. (Autoimmunity 2002)
    112. Tumour necrosis factor-alpha polymorphism and the HLA-Cw*0602 allele in psoriatic arthritis. (PubMed id 12011375)1, 4, 9 Al-Heresh A.M....McHugh N. (Rheumatology (Oxford) 2002)
    113. Interleukin-6 and interferon-gamma gene polymorphisms in the development of bronchiolitis obliterans syndrome after lung transplantation. (PubMed id 12451269)1, 4, 9 Lu K.C....Mohanakumar T. (Transplantation 2002)
    114. The G--&gt;A single nucleotide polymorphism at the -308 position in the tumor necrosis factor-alpha promoter increases the risk for severe sepsis after trauma. (PubMed id 11988644)1, 4, 9 O'Keefe G.E....Munford R.S. (J Trauma 2002)
    115. Promoter polymorphisms of the genes encoding tumor necrosis factor-alpha and interleukin-1beta are associated with different subtypes of psoriasis characterized by early and late disease onset. (PubMed id 11851889)1, 4, 9 Reich K....Neumann C. (J. Invest. Dermatol. 2002)
    116. Influence of TNFalpha and LTalpha single nucleotide polymorphisms on susceptibility to and prognosis in cutaneous malignant melanoma in the British population. (PubMed id 11841484)1, 4, 9 Howell W.M....Theaker J.M. (Eur. J. Immunogenet. 2002)
    117. Interleukin-10 and tumor necrosis factor gene polymorphisms and risk of coronary artery disease and myocardial infarction. (PubMed id 11689215)1, 4, 9 Koch W....SchAPmig A. (Atherosclerosis 2001)
    118. Cytokine gene polymorphisms in psoriasis. (PubMed id 11298547)1, 4, 9 Craven N.M....Griffiths C.E. (Br. J. Dermatol. 2001)
    119. Tumour necrosis factor-alpha promoter polymorphism in erythema nodosum. (PubMed id 11411907)1, 4, 9 Labunski S....Kunz M. (Acta Derm. Venereol. 2001)
    120. The gene polymorphism of tumor necrosis factor-beta, but not that of tumor necrosis factor-alpha, is associated with the prognosis of sarcoidosis. (PubMed id 11243953)1, 4, 9 Yamaguchi E....Kawakami Y. (Chest 2001)
    121. Polymorphisms within the tumor necrosis factor locus and prevalence of coronary artery disease in middle-aged men. (PubMed id 11257271)1, 4, 9 Keso T....Karhunen P.J. (Atherosclerosis 2001)
    122. Tumor necrosis factor, tumor necrosis factor receptors type 1 and 2, lymphotoxin-alpha, and HLA-DRB1 gene polymorphisms in human T-cell lymphotropic virus type I associated myelopathy. (PubMed id 11163081)1, 4, 9 Nishimura M....Uchiyama T. (Hum. Immunol. 2000)
    123. Tumor necrosis factor-beta gene NcoI polymorphism decreases insulin resistance in Japanese men. (PubMed id 11092520)1, 4, 9 Hayakawa T....Kobayashi K. (Metab. Clin. Exp. 2000)
    124. Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study. (PubMed id 10450718)1, 4, 9 Mira J.P....Dhainaut J.F. (JAMA 1999)
    125. Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria. (PubMed id 7935762)1, 4, 9 McGuire W....Kwiatkowski D. (Nature 1994)
    126. [Impact of TNF-alpha gene polymorphism, development of atherogenic dyslipidemia and risk of atherosclerosis]. (PubMed id 20422754)1, 4, 9 RoA-tenberg G.E....Serebriakova O.E. (Vestn. Akad. Med. Nauk SSSR 2010)
    127. Interleukin (IL)-1beta, IL-1 receptor antagonist, IL-6, IL-8, IL-10, and tumor necrosis factor alpha gene polymorphisms in patients with febrile seizures. (PubMed id 20486195)1, 4, 9 Chou I.C....Tsai F.J. (J. Clin. Lab. Anal. 2010)
    128. Tumor necrosis factor--alpha gene promoter polymorphisms in Chinese patients with nonalcoholic fatty liver diseases. (PubMed id 19637776)1, 4, 9 Hu Z.W....Tang X. (Acta Gastroenterol. Belg. 2009)
    129. Interleukin-1 receptor antagonist and tumour necrosis factor-alpha gene polymorphisms in Turkish patients with allergic contact dermatitis. (PubMed id 19706048)1, 4, 9 Ertam I....Ozkinay F. (Contact Derm. 2009)
    130. Association of TNF-alpha gene polymorphisms with systemic lupus erythematosus in Taiwanese patients. (PubMed id 19762398)1, 4, 9 Lin Y.J....Tsai F.J. (Lupus 2009)
    131. Tumor necrosis factor polymorphisms and alcoholic liver disease: a HuGE review and meta-analysis. (PubMed id 19755636)1, 4, 9 Marcos M....Laso F.J. (Am. J. Epidemiol. 2009)
    132. Tumor necrosis factor-alpha -308 genotypes influence inflammatory activity and TNF-alpha serum concentrations in children with juvenile idiopathic arthritis. (PubMed id 19208590)1, 4, 9 MourALo A.F....Fonseca J.E. (J. Rheumatol. 2009)
    133. Variation in inflammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke. (PubMed id 17981284)1, 4, 9 Bis J.C....Psaty B.M. (Atherosclerosis 2008)
    134. HLA class I and II and TNF-alpha gene polymorphisms in sarcoidosis patients. (PubMed id 19023492)1, 4, 9 Morais A....Tafulo S. (Rev Port Pneumol 2008)
    135. TNF, IFNG, IL6, IL10 and TGFB1 gene polymorphisms in South and Southeast Brazil. (PubMed id 18680515)1, 4, 9 Visentainer J.E....de Souza C.A. (Int. J. Immunogenet. 2008)
    136. Differential association of tumour necrosis factor-alpha single nucleotide polymorphism (-308) with tuberculosis and bronchial asthma. (PubMed id 19004142)1, 4, 9 Kumar V....Sehajpal P.K. (Natl Med J India 2008)
    137. Higher LPS-stimulated TNF-alpha mRNA levels in peripheral blood mononuclear cells from Chinese ankylosing spondylitis patients with -308G/A polymorphism in promoter region of tumor necrosis factor: association with distinct A33/B58/Cw10 haplotypes. (PubMed id 18719920)1, 4, 9 Lu M.C....Lai N.S. (Rheumatol. Int. 2008)
    138. Interleukin-10 (IL10) and tumor necrosis factor alpha (TNF) gene polymorphisms in Parkinson's disease patients. (PubMed id 18362084)1, 4, 9 Bialecka M....DroA_dzik M. (amp 2008)
    139. Inflammatory system gene polymorphism and the risk of stroke: a case-control study in an Indian population. (PubMed id 18158110)1, 4, 9 Banerjee I....Ganesh S. (Brain Res. Bull. 2008)
    140. Genetic polymorphisms of RANTES, IL1-A, MCP-1 and TNF-A genes in patients with prostate cancer. (PubMed id 19099590)1, 4, 9 SA!enz-LA^pez P....Ruiz-Cabello F. (BMC Cancer 2008)
    141. TNF and sTNFR1/2 plasma levels in ALS patients. (PubMed id 18083240)1, 4, 9 Cereda C....Ceroni M. (J. Neuroimmunol. 2008)
    142. Cytokine Genes TNF, IL1A, IL1B, IL6, IL1RN and IL10, and childhood-onset mood disorders. (PubMed id 18832862)1, 4, 9 Misener V.L....Barr C.L. (Neuropsychobiology 2008)
    143. Single nucleotide polymorphism in the tumor necrosis factor-alpha gene affects inflammatory bowel diseases risk. (PubMed id 18698679)1, 4, 9 Ferguson L.R....Han D.Y. (World J. Gastroenterol. 2008)
    144. IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency. (PubMed id 17690329)1, 4, 9 Demeo D.L....Silverman E.K. (Am. J. Respir. Cell Mol. Biol. 2008)
    145. [Association of immune system gene polymorphisms with quantitative features which are pathogenetically important in chronic viral hepatitis]. (PubMed id 18610832)1, 4, 9 Goncharova I.A....pyzurev V.P. (Mol. Biol. (Mosk.) 2008)
    146. Polymorphisms of the TNF, CD14, and HSPA1B genes in patients with acute alcohol-induced pancreatitis. (PubMed id 18580445)1, 4, 9 Tukiainen E....Repo H. (Pancreas 2008)
    147. Interleukin-10 and tumor necrosis factor-alpha gene polymorphisms in tuberculosis. (PubMed id 18071881)1, 4, 9 Ates O....Topal-Sarikaya A. (J. Clin. Immunol. 2008)
    148. TNFA -308G&gt;A in two international population-based cohorts and risk of asthma. (PubMed id 18385169)1, 4, 9 Castro-Giner F....Probst-Hensch N.M. (Eur. Respir. J. 2008)
    149. A study on the TNF-alpha system in Caucasian Spanish patients with alcoholic liver disease. (PubMed id 17728075)1, 4, 9 Auguet T....Richart C. (Drug Alcohol Depend 2008)
    150. HLA Dr-Dq haplotypes and the TNFA-308 polymorphism: associations with asthma and allergy. (PubMed id 17686102)1, 4, 9 Munthe-Kaas M.C....Undlien D. (Allergy 2007)
    151. Tumor necrosis factor gene polymorphisms in Tunisian patients with Behcet's disease. (PubMed id 17349875)1, 4, 9 Kamoun M....Hamzaoui K. (Hum. Immunol. 2007)
    152. Tumor necrosis factor-alpha gene promoter polymorphism in patients with familial Mediterranean fever. (PubMed id 17057944)1, 4, 9 Celebi Kobak A....Akarca U.S. (Clin. Rheumatol. 2007)
    153. IL1 and TNF gene polymorphisms in patients with juvenile idiopathic arthritis treated with TNF inhibitors. (PubMed id 17324969)1, 4, 9 Cimaz R....Miossec P. (Ann. Rheum. Dis. 2007)
    154. Tumor necrosis factor alpha -238G&gt;A genotype alters postprandial plasma levels of free fatty acids in obese individuals with type 2 diabetes mellitus. (PubMed id 17445540)1, 4, 9 Fontaine-Bisson B....El-Sohemy A. (Metab. Clin. Exp. 2007)
    155. A novel gene variation of TNFalpha associated with ankylosing spondylitis: a reconfirmed study. (PubMed id 17472990)1, 4, 9 Zhu X....Yang Z. (Ann. Rheum. Dis. 2007)
    156. Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media. (PubMed id 17908769)1, 4, 9 Emonts M....Sanders E.A. (Pediatrics 2007)
    157. Parental smoking modifies the relation between genetic variation in tumor necrosis factor-alpha (TNF) and childhood asthma. (PubMed id 17450233)1, 4, 9 Wu H....London S.J. (Environ. Health Perspect. 2007)
    158. Polymorphisms of tumor necrosis factor-alpha, interleukin-10, cytochrome P450 3A5 and ABCB1 in Chinese liver transplant patients treated with immunosuppressant tacrolimus. (PubMed id 17568575)1, 4, 9 Li D....Zhang G.L. ( international journal of clinical chemistry 2007)
    159. Association of TNF-alpha gene promoter C-857T polymorphism with higher serum LDL cholesterol levels and carotid plaque formation in Japanese patients with type 2 diabetes. (PubMed id 17347550)1, 4, 9 Yamashina M....Satoh J. (Tohoku J. Exp. Med. 2007)
    160. Polymorphisms in the IL-4, IL-4 receptor alpha chain, TNF-alpha, and lymphotoxin-alpha genes and risk of asthma in Hong Kong Chinese adults. (PubMed id 17536219)1, 4, 9 Mak J.C....Chan-Yeung M. (Int. Arch. Allergy Immunol. 2007)
    161. TNF-alpha, TNF-beta and IL-4 gene polymorphisms in Iranian patients with multiple sclerosis. (PubMed id 17295710)1, 4, 9 Kamali-Sarvestani E....Gharesi-Fard B. (Acta Neurol. Scand. 2007)
    162. Association between human African trypanosomiasis and the IL6 gene in a Congolese population. (PubMed id 16720107)1, 4, 9 Courtin D....Garcia A. (Infect. Genet. Evol. 2007)
    163. Role of genetic polymorphisms in ACE and TNF-alpha gene in sarcoidosis: a meta-analysis. (PubMed id 17768594)1, 4, 9 Medica I....Peterlin B. (J. Hum. Genet. 2007)
    164. Association between polymorphism of tumour necrosis factor alpha-308 gene promoter and asthma: a meta-analysis. (PubMed id 16517578)1, 4, 9 Gao J....Gao X. (Thorax 2006)
    165. [Association between tumor necrosis factor-alpha promoter polymorphisms and type 2 diabetes and obesity in Chilean elderly women]. (PubMed id 17167711)1, 4, 9 Santos M J.L....Albala B C. (Rev Med Chil 2006)
    166. An association between asthma and TNF-308G/A polymorphism: meta-analysis. (PubMed id 16865291)1, 4, 9 Aoki T....Noguchi E. (J. Hum. Genet. 2006)
    167. The effects of genetic polymorphisms of IL-1 and TNF-A on Helicobacter pylori-induced gastroduodenal diseases in Korea. (PubMed id 16579840)1, 4, 9 Kim N....Song I.S. (Helicobacter 2006)
    168. Associations of tumour necrosis factor alpha promoter polymorphisms at position -308 and -238 with clinical characteristics of chronic hepatitis C. (PubMed id 17052277)1, 4, 9 Dai C.Y....Yu M.L. (J. Viral Hepat. 2006)
    169. Tumor necrosis factor alpha promoter polymorphisms in patients with juvenile idiopathic arthritis. (PubMed id 16539828)1, 4, 9 Schmeling H....Horneff G. (Clin. Exp. Rheumatol. 2006)
    170. [Association among serous and cerebrospinal fluid TNF-alpha level, gene polymorphisms of TNF-alpha and multiple sclerosis in Han nationality of southern China]. (PubMed id 17160953)1, 4, 9 Dong Y.X....Lin P.Y. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2006)
    171. Association of-238G/A and -857C/T polymorphisms of tumor necrosis factor-alpha gene promoter region with outcomes of hepatitis B virus infection. (PubMed id 16827185)1, 4, 9 Li H.Q....Li H. (Biomed. Environ. Sci. 2006)
    172. Interaction of the -308G/A promoter polymorphism of the tumor necrosis factor-alpha gene with single-nucleotide polymorphism 45 of the adiponectin gene: effect on serum adiponectin concentrations in a Spanish population. (PubMed id 16254197)1, 4, 9 GonzA!lez-SA!nchez J.L....Serrano-RA-os M. (Clin. Chem. 2006)
    173. Association of TNF-alpha, TNF-beta, IFN-gamma and IL-1Ra gene polymorphisms with Graves' disease in the Thai population. (PubMed id 17348243)1, 4, 9 Nakkuntod J....Hirankarn N. (Asian Pac. J. Allergy Immunol. 2006)
    174. Association of TNF-alpha genetic polymorphism with HLA DPB1*0301. (PubMed id 17014432)1, 4, 9 Kim S.H....Park H.S. (Clin. Exp. Allergy 2006)
    175. Analysis of linkage between lymphotoxin alpha haplotype and polymorphisms in 5'-flanking region of tumor necrosis factor alpha gene associated with efficacy of infliximab for Crohn's disease patients. (PubMed id 17049565)1, 4, 9 Ozeki T....Yamada Y. (Mutat. Res. 2006)
    176. Lack of association of tumor necrosis factor-alpha gene polymorphisms with disease susceptibility and severity in BehAset's disease. (PubMed id 15875188)1, 4, 9 AteA9 A....Duman M. (Rheumatol. Int. 2006)
    177. Cytokine gene polymorphisms in bullous pemphigoid in a Chinese population. (PubMed id 16403098)1, 4, 9 Chang Y.T....Tsai S.F. (Br. J. Dermatol. 2006)
    178. [Tumor necrosis factor alpha (TNF-alpha) gene G-308A polymorphism relationship to insulin resistance and lipid abnormalities in children with obesity]. (PubMed id 17020650)1, 4, 9 Pyrzak B....Rymkiewicz-KluczyA8ska B. (Endokrynol Diabetol Chor Przemiany Materii Wieku Rozw 2006)
    179. Associations of tumor necrosis factor G-308A with childhood asthma and wheezing. (PubMed id 16456144)1, 4, 9 Li Y.F....Gilliland F.D. (Am. J. Respir. Crit. Care Med. 2006)
    180. Association of TNFd and IL-10 polymorphisms with mortality in unrelated hematopoietic stem cell transplantation. (PubMed id 16699452)1, 4, 9 Bettens F....Tiercy J.M. (Transplantation 2006)
    181. Polymorphism of the TNF-alpha, HSP70-2, and CD14 genes increases susceptibility to severe acute pancreatitis. (PubMed id 15714129)1, 4, 9 Balog A....MA!ndi Y. (Pancreas 2005)
    182. Clinical importance of transforming growth factor-beta but not of tumor necrosis factor-alpha gene polymorphisms in patients with the myelodysplastic syndrome belonging to the refractory anemia subtype. (PubMed id 15860935)1, 4, 9 Balog A....MA!ndi Y. (Pathobiology 2005)
    183. The influence of a polymorphism at position -857 of the tumour necrosis factor alpha gene on clinical response to etanercept therapy in rheumatoid arthritis. (PubMed id 15695296)1, 4, 9 Kang C.P....Bae S.C. (Rheumatology (Oxford) 2005)
    184. TNFalpha and IL10 SNPs act together to predict disease behaviour in Crohn's disease. (PubMed id 15937090)1, 4, 9 Fowler E.V....Radford-Smith G.L. (J. Med. Genet. 2005)
    185. Association of tumour necrosis factor-alpha, lymphotoxin-alpha and HLA-DRB1 gene polymorphisms with LAPfgren's syndrome in Czech patients with sarcoidosis. (PubMed id 15713215)1, 4, 9 Mrazek F....Petrek M. (Tissue Antigens 2005)
    186. Inflammatory gene polymorphisms influence risk of postoperative morbidity after lung resection. (PubMed id 15854959)1, 4, 9 Shaw A.D....Dickey B.F. (Ann. Thorac. Surg. 2005)
    187. Influence of cytokine and ICAM-1 gene polymorphisms on susceptibility to chronic pancreatitis. (PubMed id 15917409)1, 4, 9 Howell W.M....Bateman A.C. (J. Clin. Pathol. 2005)
    188. Interleukin 1 receptor antagonist and tumor necrosis factor-alpha gene polymorphism in patients with end-stage renal failure. (PubMed id 15717635)1, 4, 9 Shu K.H....Lee W.C. (Ren Fail 2005)
    189. Correlation between a gene polymorphism of tumor necrosis factor and inflammatory bowel disease. (PubMed id 16246225)1, 4, 9 Song Y....Fan D.M. (Chin J Dig Dis 2005)
    190. Tumor necrosis factor-alpha microsatellite polymorphism association with rheumatoid arthritis in Indian patients. (PubMed id 16099338)1, 4, 9 Agrawal C....Das H.R. (Arch. Med. Res. 2005)
    191. Meta-analysis on the G-308A tumor necrosis factor alpha gene variant and phenotypes associated with the metabolic syndrome. (PubMed id 16421346)1, 4, 9 Sookoian S.C....Pirola C.J. (Obes. Res. 2005)
    192. Heat shock protein 70 and tumor necrosis factor alpha in Taiwanese patients with dementia. (PubMed id 15832029)1, 4, 9 Fung H.C....Lee-Chen G.J. (Dement Geriatr Cogn Disord 2005)
    193. Influence of toll-like receptor 4, CD14, tumor necrosis factor, and interleukine-10 gene polymorphisms on clinical outcome in Japanese critically ill patients. (PubMed id 16051275)1, 4, 9 Nakada T.A....Tokuhisa T. (J. Surg. Res. 2005)
    194. [The role of genetic polymorphisms within tumor necrosis factor promoter gene in non-Hodgkin's lymphomas]. (PubMed id 16786763)1, 4, 9 JuszczyA8ski P....Warzocha K. (Prz. Lek. 2005)
    195. Are genetic polymorphisms of tumour necrosis factor alpha, interleukin-10, CD14 endotoxin receptor or manganese superoxide dismutase associated with alcoholic liver disease? (PubMed id 16148556)1, 4, 9 Martins A....Camilo M.E. (amp 2005)
    196. Impact of cytokine gene polymorphism on cardiovascular risk in renal transplant recipients. (PubMed id 15910294)1, 4, 9 Altun B....Turgan C. (Transpl. Int. 2005)
    197. Extended haplotype analysis reveals an association of TNF polymorphisms with susceptibility to systemic lupus erythematosus beyond HLA-DR3. (PubMed id 16095006)1, 4, 9 Schotte H....SchlA1ter B. (Scand. J. Rheumatol. 2005)
    198. Lack of a strong association between HLA class II, tumour necrosis factor and transporter associated with antigen processing gene polymorphisms and virological response to alpha-interferon treatment in patients with chronic hepatitis C. (PubMed id 15548263)1, 4, 9 Airoldi A....Pinzello G. (Eur. J. Immunogenet. 2004)
    199. Relevance of IL10, TGFbeta1, TNFalpha, and IL4Ralpha gene polymorphisms in kidney transplantation: a collaborative transplant study report. (PubMed id 15367225)1, 4, 9 Mytilineos J....Opelz G. (Am. J. Transplant. 2004)
    200. Genetic polymorphisms in tumor necrosis factor (TNF)-alpha and TNF-beta in a population-based study of systemic lupus erythematosus: associations and interaction with the interleukin-1alpha-889 C/T polymorphism. (PubMed id 15219382)1, 4, 9 Parks C.G....Cooper G.S. (Hum. Immunol. 2004)
    201. Polymorphisms in the promoter region of tumor necrosis factor alpha (TNF-alpha) and the HLA-DRB1 locus in Mexican mestizo patients with ulcerative colitis. (PubMed id 15325795)1, 4, 9 Yamamoto-Furusho J.K....Granados J. (Immunol. Lett. 2004)
    202. Innate immunity genes influence the severity of acute appendicitis. (PubMed id 15273551)1, 4, 9 Rivera-Chavez F.A....O'Keefe G.E. (Ann. Surg. 2004)
    203. Are pANCA, ASCA, or cytokine gene polymorphisms associated with pouchitis? Long-term follow-up in 102 ulcerative colitis patients. (PubMed id 15056081)1, 4, 9 Aisenberg J....Sachar D.B. (Am. J. Gastroenterol. 2004)
    204. Polymorphism of stress protein HSP70-2 gene in Tunisians: susceptibility implications in type 2 diabetes and obesity. (PubMed id 15223990)1, 4, 9 Zouari Bouassida K....Danguir J. (amp 2004)
    205. [Allelic variants of the tumor necrosis factor superfamily as markers of the severity of the course of chronic obstructive lung disease and bronchiectatic disease]. (PubMed id 15174288)1, 4, 9 Ianbaeva D.G....Viktorova T.V. (Genetika 2004)
    206. Polymorphisms of tumor necrosis factor (TNF) alpha and beta genes in Korean patients with psoriasis. (PubMed id 12709814)1, 4, 9 Kim T.G....Kim T.Y. (Arch. Dermatol. Res. 2003)
    207. A study of candidate genes for psoriasis near HLA-C in Chinese patients with psoriasis. (PubMed id 12653732)1, 4, 9 Chang Y.T....Wong C.K. (Br. J. Dermatol. 2003)
    208. IL-10 and TNF-alpha polymorphisms in a sample of Sicilian patients affected by tuberculosis: implication for ageing and life span expectancy. (PubMed id 12714269)1, 4, 9 Scola L....Lio D. (Mech. Ageing Dev. 2003)
    209. The effect of the -308A allele of the TNF-alpha gene on insulin action is dependent on obesity. (PubMed id 12855762)1, 4, 9 PihlajamAoki J....Laakso M. (Obes. Res. 2003)
    210. Variation in the TNF gene promoter and risk of osteolysis after total hip arthroplasty. (PubMed id 14606512)1, 4, 9 Wilkinson J.M....Eastell R. (J. Bone Miner. Res. 2003)
    211. Tumor necrosis factor genetic polymorphisms and response to antiviral therapy in patients with chronic hepatitis C. (PubMed id 11922568)1, 4, 9 Rosen H.R....Chou S. (Am. J. Gastroenterol. 2002)
    212. Differential association of polymorphisms in the TNFalpha region with psoriatic arthritis but not psoriasis. (PubMed id 11830425)1, 4, 9 HAPhler T....MAorker-Hermann E. (Ann. Rheum. Dis. 2002)
    213. Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors. (PubMed id 12019209)1, 4, 9 van Heel D.A....Kwiatkowski D. (Hum. Mol. Genet. 2002)
    214. [Tumor necrosis factor alpha HLA-DRB(1) gene polymorphism and genetic susceptibility to cirrhosis]. (PubMed id 12654235)1, 4, 9 Lin J....Liang K. (Zhonghua Nei Ke Za Zhi 2002)
    215. The TNF alpha/G-308A polymorphism influences insulin sensitivity in offspring of patients with coronary heart disease: the European Atherosclerosis Research Study II. (PubMed id 11888514)1, 4, 9 Nicaud V....Tiret L. (Atherosclerosis 2002)
    216. Polymorphisms in the interleukin-10, tumor necrosis factor-alpha, and transforming growth factor-beta1 genes in chronic hepatitis C patients treated with interferon and ribavirin. (PubMed id 11830340)1, 4, 9 Vidigal P.G....Zein N.N. (J. Hepatol. 2002)
    217. [Significance of tumor necrosis factor-alpha gene polymorphism in patients with acute severe pancreatitis]. (PubMed id 12609060)1, 4, 9 Zhang D....Tang X. (Zhonghua Yi Xue Za Zhi 2002)
    218. Tumor necrosis factor gene polymorphisms, leukocyte function, and sepsis susceptibility in blunt trauma patients. (PubMed id 12414751)1, 4, 9 Majetschak M....Heesen M. (Clin. Diagn. Lab. Immunol. 2002)
    219. Increased frequency of the uncommon tumor necrosis factor -857T allele in British and Dutch patients with sarcoidosis. (PubMed id 11956055)1, 4, 9 Grutters J.C....Welsh K.I. (Am. J. Respir. Crit. Care Med. 2002)
    220. Polymorphisms in candidate obesity genes and their interaction with dietary intake of n-6 polyunsaturated fatty acids affect obesity risk in a sub-sample of the EPIC-Heidelberg cohort. (PubMed id 12395215)1, 4, 9 Nieters A....Linseisen J. (Eur J Nutr 2002)
    221. Bone mineral mass is associated with interleukin 1 receptor autoantigen and TNF-alpha gene polymorphisms in post-menopausal Mediterranean women. (PubMed id 12240899)1, 4, 9 Fontova R....Richart C. (J. Endocrinol. Invest. 2002)
    222. Analysis of tumor necrosis factor-alpha, lymphotoxin-alpha, tumor necrosis factor receptor II, and interleukin-6 polymorphisms in patients with idiopathic pulmonary fibrosis. (PubMed id 11371414)1, 4, 9 Pantelidis P....Du Bois R.M. (Am. J. Respir. Crit. Care Med. 2001)
    223. Polymorphism of tumor necrosis factor in esophageal, gastric or colorectal carcinoma. (PubMed id 11379335)1, 4, 9 Saito S....Nakao A. (Hepatogastroenterology 2001)
    224. Tumor necrosis factor-alpha gene polymorphisms in children with multiple sclerosis. (PubMed id 11571703)1, 4, 9 Anlar B....Yakut A. (Neuropediatrics 2001)
    225. Tumor necrosis factor promoter polymorphisms in patients with rheumatoid arthritis in Taiwan. (PubMed id 11508580)1, 4, 9 Yen J.H....Liu H.W. (J. Rheumatol. 2001)
    226. Association of tumor necrosis factor alpha gene promoter polymorphism with the presence of chronic obstructive pulmonary disease. (PubMed id 11179116)1, 4, 9 Sakao S....Kuriyama T. (Am. J. Respir. Crit. Care Med. 2001)
    227. Major histocompatibility locus genetic markers of beryllium sensitization and disease. (PubMed id 11716174)1, 4, 9 Saltini C....Tinelli C. (Eur. Respir. J. 2001)
    228. Interethnic studies of TNF polymorphisms confirm the likely presence of a second MHC susceptibility locus in ankylosing spondylitis. (PubMed id 11196671)1, 4, 9 Milicic A....Brown M.A. (Genes Immun. 2000)
    229. Lack of association between adult asthma and the tumour necrosis factor alpha-308 polymorphism gene. (PubMed id 11106199)1, 4, 9 Louis R....Louis E. (Eur. Respir. J. 2000)
    230. Investigation of TNFA 308G &gt; A and TNFB 252G &gt; A polymorphisms in genetic susceptibility to migraine. (PubMed id 20035431)1, 4, 9 Ghosh J....Mittal B. (J. Neurol. 2010)
    231. Genetic susceptibility to different clinical forms of tuberculosis in the Peruvian population. (PubMed id 20188863)1, 4, 9 Taype C.A....Shaw M.A. (Infect. Genet. Evol. 2010)
    232. Polymorphisms in TNF and HSP-70 show a significant association with gastric cancer and duodenal ulcer. (PubMed id 19626584)1, 4, 9 Partida-RodrA-guez O....Perez-RodrA-guez M. (Int. J. Cancer 2010)
    233. The role of tumor necrosis factor alpha G-308A polymorphisms in the course of pulmonary sarcoidosis. (PubMed id 20070603)1, 4, 9 Wijnen P.A....Drent M. (Tissue Antigens 2010)
    234. Meta-analysis of TNF-alpha promoter - 238A/G polymorphism and SLE susceptibility. (PubMed id 20166876)1, 4, 9 Zou Y.F....Ye D.Q. (Autoimmunity 2010)
    235. TNF-alpha and IL-10 gene polymorphisms show a weak association with pemphigus vulgaris in the Slovak population. (PubMed id 19470040)1, 4, 9 Javor J....Svecova D. (J Eur Acad Dermatol Venereol 2010)
    236. Cytokine gene polymorphisms in BehAset's disease and their association with clinical and laboratory findings. (PubMed id 19796538)1, 4, 9 Dilek K....Oral H.B. (Clin. Exp. Rheumatol. 2009)
    237. Lack of association of TNF-alpha promoter polymorphisms with ankylosing spondylitis: a meta-analysis. (PubMed id 19720680)1, 4, 9 Lee Y.H. and Song G.G. (Rheumatology (Oxford) 2009)
    238. Tumor necrosis factor-alpha is a common genetic risk factor for asthma, juvenile rheumatoid arthritis, and systemic lupus erythematosus in a Mexican pediatric population. (PubMed id 19480843)1, 4, 9 JimAcnez-Morales S....Orozco L. (Hum. Immunol. 2009)
    239. Does the simultaneous tumor necrosis factor receptor 2, tumor necrosis factor promoter gene polymorphism represent a higher risk for alcoholic liver disease? (PubMed id 19212208)1, 4, 9 Machado M.V....Cortez-Pinto H. (amp 2009)
    240. Association between inflammatory gene polymorphisms and coronary artery disease in an Indian population. (PubMed id 18157711)1, 4, 9 Banerjee I....Ganesh S. (J. Thromb. Thrombolysis 2009)
    241. Effect of desensitization in solid organ transplant recipients depends on some cytokines genes polymorphism. (PubMed id 19332120)1, 4, 9 Lobashevsky A.L....Turrentine M.W. (Transpl. Immunol. 2009)
    242. -308G&gt;A and -1031T&gt;C tumor necrosis factor gene polymorphisms in Tunisian patients with coronary artery disease. (PubMed id 19803813)1, 4, 9 Ghazouani L....Mahjoub T. (Clin. Chem. Lab. Med. 2009)
    243. TNF-alpha gene polymorphisms in Iranian Azeri Turkish patients with Behcet's Disease. (PubMed id 19774383)1, 4, 9 Bonyadi M....Dastgiri S. (Rheumatol. Int. 2009)
    244. Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE II. (PubMed id 19267370)1, 4, 9 Wang M.H....Platz E.A. (Prostate 2009)
    245. Independent and additive interactive effects among tumor necrosis factor-alpha polymorphisms, substance use habits, and chronic hepatitis B and hepatitis C virus infection on risk for hepatocellular carcinoma. (PubMed id 19910749)1, 4, 9 Jeng J.E....Chang J.G. (Medicine (Baltimore) 2009)
    246. TNF and LTA gene, allele, and extended HLA haplotype associations with severe dengue virus infection in ethnic Thais. (PubMed id 19392621)1, 4, 9 Vejbaesya S....Stephens H.A. (J. Infect. Dis. 2009)
    247. Analysis of inflammation- and atherosclerosis-related gene polymorphisms in branch retinal vein occlusion. (PubMed id 19347053)1, 4, 9 Steinbrugger I....Weger M. (Mol. Vis. 2009)
    248. TNF, LTA and TGFB1 genotype distributions among acute graft-vs-host disease subsets after HLA-matched unrelated hematopoietic stem cell transplantation: a pilot study. (PubMed id 19392797)1, 4, 9 Shah R.... Posch P.E. (Tissue Antigens 2009)
    249. Cytokine gene polymorphisms and BALF cytokine levels in interstitial lung diseases. (PubMed id 19117745)1, 4, 9 Vasakova M....Striz I. (Respir Med 2009)
    250. Association of interferon-gamma and tumor necrosis factor alpha polymorphisms with susceptibility to vitiligo in Iranian patients. (PubMed id 18820938)1, 4, 9 Namian A.M....Kamali-Sarvestani E. (Arch. Dermatol. Res. 2009)
    251. Polymorphisms of tumor necrosis factor alpha gene and coronary heart disease in a Chinese Han population: interaction with cigarette smoking. (PubMed id 18814905)1, 4, 9 Hou L....Gu D. (Thromb. Res. 2009)
    252. Genetic variants in immunoregulatory genes and risk for childhood lymphomas. (PubMed id 19508433)1, 4, 9 Andrie E....Petridou E.T. (Eur. J. Haematol. 2009)
    253. The relation of adiponectin and tumor necrosis factor alpha levels between endothelial nitric oxide synthase, angiotensin-converting enzyme, transforming growth factor beta, and tumor necrosis factor alpha gene polymorphism in adrenal incidentalomas. (PubMed id 19498318)1, 4, 9 Harman E....Yilmaz C. (J. Endocrinol. Invest. 2009)
    254. Cytokine gene polymorphisms in heavy drinkers with and without decompensated liver disease: a case-control study. (PubMed id 19086955)1, 4, 9 Gleeson D....Duff G.W. (Am. J. Gastroenterol. 2008)
    255. Association of cystic fibrosis transmembrane conductance regulator (CFTR) mutation/variant/haplotype and tumor necrosis factor (TNF) promoter polymorphism in hyperlipidemic pancreatitis. (PubMed id 17981921)1, 4, 9 Chang Y.T....Wong J.M. (Clin. Chem. 2008)
    256. The -308 TNFalpha gene polymorphism in severe acute alcoholic hepatitis: identification of a new susceptibility marker. (PubMed id 18336639)1, 4, 9 Nguyen-Khac E....Naassila M. (Alcohol. Clin. Exp. Res. 2008)
    257. Relationship between periodontal findings and the TNF-alpha Gene 1031T/C polymorphism in Turkish patients with BehAset's disease. (PubMed id 18355201)1, 4, 9 Akman A....Yegin O. (J Eur Acad Dermatol Venereol 2008)
    258. Genetic markers of tumour necrosis factor alpha in aggressive and chronic periodontitis. (PubMed id 18363738)1, 4, 9 Schulz S....Reichert S. (J. Clin. Periodontol. 2008)
    259. Genetic factors of susceptibility and of severity in primary biliary cirrhosis. (PubMed id 18930330)1, 4, 9 Poupon R....Barbu V. (J. Hepatol. 2008)
    260. Impact of genetic polymorphisms of leptin and TNF-alpha on rosiglitazone response in Chinese patients with type 2 diabetes. (PubMed id 18438653)1, 4, 9 Liu H.L....Liu Z.Q. (Eur. J. Clin. Pharmacol. 2008)
    261. Tumour necrosis factor gene polymorphisms are associated with COPD. (PubMed id 18256059)1, 4, 9 Gingo M.R....Bowler R.P. (Eur. Respir. J. 2008)
    262. Lack of association between the TNF-alpha -308 (G/A) genetic polymorphism and periodontal disease in Brazilians. (PubMed id 19148387)1, 4, 9 Menezes N.G. and Colombo A.P. (Braz Oral Res 2008)
    263. New approach reveals CD28 and IFNG gene interaction in the susceptibility to cervical cancer. (PubMed id 18337305)1, 4, 9 Guzman V.B....Morgun A. (Hum. Mol. Genet. 2008)
    264. Polymorphisms in cytokine genes and their association with acute rejection and recurrence of hepatitis B in Chinese liver transplant recipients. (PubMed id 18375254)1, 4, 9 Xie H.Y....Zheng S.S. (Arch. Med. Res. 2008)
    265. Evaluation of functional single nucleotide polymorphisms of different genes coding for the immunoregulatory molecules in patients with monoclonal large granular lymphocyte lymphocytosis. (PubMed id 18361934)1, 4, 9 Garrido P....Ruiz-Cabello F. (Hum. Immunol. 2008)
    266. Association of TNF-alpha and TNFR1 promoters and 3' UTR region of TNFR2 gene polymorphisms with genetic susceptibility to tobacco-related oral carcinoma in Asian Indians. (PubMed id 18206417)1, 4, 9 Gupta R....Das S.N. (Oral Oncol. 2008)
    267. Serum TNF-alpha levels in relation to alcohol consumption and common TNF gene polymorphisms. (PubMed id 18579335)1, 4, 9 Gonzalez-Quintela A....Gude F. (Alcohol 2008)
    268. Haplotypes of tumor necrosis factor gene and tracheal aspirate fluid levels of tumor necrosis factor-alpha in preterm infants. (PubMed id 18645461)1, 4, 9 Kazzi S.N....Buhimschi I.A. (Pediatr. Res. 2008)
    269. Human leucocyte antigen and TNFalpha polymorphism association in microscopic colitis. (PubMed id 18334870)1, 4, 9 Koskela R.M....Karttunen R.A. (amp 2008)
    270. Genetic variations in inflammatory mediators influence lung disease progression in cystic fibrosis. (PubMed id 19009622)1, 4, 9 Corvol H....Clement A. (Pediatr. Pulmonol. 2008)
    271. Epistatic interactions are critical to gene-association studies: PAI-1 and risk for mortality after burn injury. (PubMed id 18182917)1, 4, 9 Barber R.C....Horton J.W. (amp 2008)
    272. Polymorphisms in the CD14 and IL-6 genes associated with periodontal disease. (PubMed id 17448042)1, 4, 9 Tervonen T....Karttunen R. (J. Clin. Periodontol. 2007)
    273. Cytokine gene polymorphisms in Colombian patients with systemic lupus erythematosus. (PubMed id 17711410)1, 4, 9 Guarnizo-Zuccardi P....Vasquez G. (Tissue Antigens 2007)
    274. IL-10 and IL-6 gene polymorphisms as potential host susceptibility factors in Brucellosis. (PubMed id 17544674)1, 4, 9 Budak F....Oral H.B. (Cytokine 2007)
    275. Analysis of polymorphisms of tumor necrosis factor-alpha and polymorphic xenobiotic metabolizing enzymes in inflammatory bowel disease: study from northern India. (PubMed id 17565649)1, 4, 9 Mittal R.D....Ghoshal U.C. (J. Gastroenterol. Hepatol. 2007)
    276. Frequency distribution of cytokine gene polymorphisms in the healthy North Indian population. (PubMed id 17257312)1, 4, 9 Kaur G....Mehra N.K. (Tissue Antigens 2007)
    277. The -308 tumour necrosis factor-alpha gene polymorphism predicts therapeutic response to TNFalpha-blockers in rheumatoid arthritis and spondyloarthritis patients. (PubMed id 16720636)1, 4, 9 Seitz M....Villiger P.M. (Rheumatology (Oxford) 2007)
    278. Development of a novel microarray methodology for the study of SNPs in the promoter region of the TNF-alpha gene: their association with obstructive pulmonary disease in Greek patients. (PubMed id 17509552)1, 4, 9 Papatheodorou A....Tzetis M. (Clin. Biochem. 2007)
    279. Cytokine genotype and phenotype effects on lung function decline in firefighters. (PubMed id 17351514)1, 4, 9 Josyula A.B....Burgess J.L. (J. Occup. Environ. Med. 2007)
    280. Phenotype selection for detecting variable genes: a survey of cardiovascular quantitative traits and TNF locus polymorphism. (PubMed id 17356550)1, 4, 9 Hong M.G....Prince J.A. (Eur. J. Hum. Genet. 2007)
    281. Polymorphisms of tumor necrosis factor-alpha but not MDR1 influence response to medical therapy in pediatric-onset inflammatory bowel disease. (PubMed id 17255827)1, 4, 9 Cucchiara S....Annese V. (J. Pediatr. Gastroenterol. Nutr. 2007)
    282. Genetic susceptibility to SLE is associated with TNF-alpha gene polymorphism -863, but not -308 and -238, in Thai population. (PubMed id 18001298)1, 4, 9 Hirankarn N....Wongpiyabovorn J. (Int. J. Immunogenet. 2007)
    283. IL2 and TNFA gene polymorphisms and the risk of graft-versus-host disease after allogeneic haematopoietic stem cell transplantation. (PubMed id 18021367)1, 4, 9 Viel D.O....Visentainer J.E. (Scand. J. Immunol. 2007)
    284. Tumor necrosis factor-alpha gene polymorphism correlates with cardiovascular disease in patients with end-stage renal disease. (PubMed id 17705580)1, 4, 9 Buraczynska M....Ksiazek A. (amp 2007)
    285. Immune mechanisms in non-Hodgkin lymphoma: joint effects of the TNF G308A and IL10 T3575A polymorphisms with non-Hodgkin lymphoma risk factors. (PubMed id 17510437)1, 4, 9 Wang S.S....Hartge P. (Cancer Res. 2007)
    286. Significant association between TNF-alpha (TNF) promoter allele (-1031C, -863C, and -857C) and cerebral malaria in Thailand. (PubMed id 17493155)1, 4, 9 Hananantachai H....Tokunaga K. (Tissue Antigens 2007)
    287. [Association of cytokines genes (ILL, IL1RN, TNF, LTA, IL6, IL8, IL0) polymorphic markers with chronic obstructive pulmonary disease]. (PubMed id 17380888)1, 4, 9 Danilko K.V....Victorova T.V. (Mol. Biol. (Mosk.) 2007)
    288. Analysis of IL-1A(-889) and TNFA(-308) gene polymorphism in Brazilian patients with generalized aggressive periodontitis. (PubMed id 17823082)1, 4, 9 Maria de Freitas N....Lotufo R.F. (Eur. Cytokine Netw. 2007)
    289. TNF polymorphisms in psoriasis: association of psoriatic arthritis with the promoter polymorphism TNF*-857 independent of the PSORS1 risk allele. (PubMed id 17530646)1, 4, 9 Reich K....Burkhardt H. (Arthritis Rheum. 2007)
    290. Tumour necrosis factor and lymphotoxin A polymorphisms and lung function in smokers. (PubMed id 16971410)1, 4, 9 Tanaka G....He J.Q. (Eur. Respir. J. 2007)
    291. Association of polymorphisms within the promoter region of the tumor necrosis factor-alpha with clinical outcomes of rheumatic fever. (PubMed id 17079017)1, 4, 9 Ramasawmy R....Guilherme L. (Mol. Immunol. 2007)
    292. GSTM1 and TNF-alpha gene polymorphisms and relations between blood lead and inflammatory markers in a non-occupational population. (PubMed id 17298885)1, 4, 9 Kim J.H....Hong Y.C. (Mutat. Res. 2007)
    293. Association of TNF-alpha -308 G/A and IL-4 -589 C/T gene promoter polymorphisms with asthma susceptibility in the south of Iran. (PubMed id 18088017)1, 4, 9 Kamali-Sarvestani E....Nekoee A. (amp 2007)
    294. Cytokine gene polymorphisms can alter the effect of Bacillus Calmette-GuAcrin (BCG) immunotherapy. (PubMed id 16938461)1, 4, 9 Basturk B....Oktay B. (Cytokine 2006)
    295. Association of HLA-A, -B, -C genes and TNF microsatellite polymorphism with psoriasis vulgaris: a study of genetic risk in Brazilian patients. (PubMed id 17101473)1, 4, 9 Biral A.C....Kraemer M.H. (Eur J Dermatol 2006)
    296. Association between chronic hepatitis B virus infection and interleukin-10, tumor necrosis factor-alpha gene promoter polymorphisms. (PubMed id 16824070)1, 4, 9 Cheong J.Y....Kim J.H. (J. Gastroenterol. Hepatol. 2006)
    297. Alleles 308A and 238A in the tumor necrosis factor alpha gene promoter do not increase the risk of severe malaria in children with Plasmodium falciparum infection in Mali. (PubMed id 16982833)1, 4, 9 Cabantous S....Marquet S. (Infect. Immun. 2006)
    298. Tumour necrosis factor microsatellite haplotypes are associated with chronic pancreatitis. (PubMed id 16407614)1, 4, 9 O'Reilly D.A....Kingsnorth A.N. (JOP 2006)
    299. Role of single nucleotide polymorphisms of cytokine genes in spontaneous preterm delivery. (PubMed id 17145371)1, 4, 9 Speer E.M....Skoner D.P. (Hum. Immunol. 2006)
    300. Analysis of tumor necrosis factor-alpha, transforming growth factor-beta, interleukin-10, IL-6, and interferon-gamma gene polymorphisms in patients with chronic periodontitis. (PubMed id 17209781)1, 4, 9 Babel N....Reinke P. (J. Periodontol. 2006)
    301. Three allele combinations associated with multiple sclerosis. (PubMed id 16872485)1, 4, 9 Favorova O.O....Ochs M.F. (BMC Med. Genet. 2006)
    302. Meta-analysis of TNF-alpha promoter -308 A/G polymorphism and SLE susceptibility. (PubMed id 16418737)1, 4, 9 Lee Y.H....Nath S.K. (Eur. J. Hum. Genet. 2006)
    303. Association between vitamin D receptor, CCR5, TNF-alpha and TNF-beta gene polymorphisms and HBV infection and severity of liver disease. (PubMed id 16545485)1, 4, 9 Suneetha P.V....Hissar S. (J. Hepatol. 2006)
    304. Cytokine tumor necrosis factor-alpha A promoter gene polymorphism at position -308 G--&gt;A and pediatric inflammatory bowel disease: implications in ulcerative colitis and Crohn's disease. (PubMed id 16707968)1, 4, 9 SA1kora J....StozickA1 F. (J. Pediatr. Gastroenterol. Nutr. 2006)
    305. Involvement of -308 TNF-alpha and 1267 Hsp70-2 polymorphisms and zinc status in the susceptibility of coronary artery disease (CAD) in old patients. (PubMed id 16953332)1, 4, 9 Giacconi R....Mocchegiani E. (Biogerontology 2006)
    306. Tumor necrosis factor- alpha promoter polymorphism at position -308 predicts response to combination therapy in hepatitis C virus infection. (PubMed id 16323137)1, 4, 9 Dai C.Y....Yu M.L. (J. Infect. Dis. 2006)
    307. Interleukin-10 or tumor necrosis factor-alpha polymorphisms and the natural course of hepatitis C virus infection in a hyperendemic area of Japan. (PubMed id 16698276)1, 4, 9 Kusumoto K....Tsubouchi H. (Cytokine 2006)
    308. Association of TNF-alpha serum levels and TNFA promoter polymorphisms with risk of myocardial infarction. (PubMed id 16243340)1, 4, 9 Bennet A.M....de Faire U. (Atherosclerosis 2006)
    309. Polymorphisms within the tumor necrosis factor-alpha promoter region in patients with HLA-B27-associated uveitis: association with susceptibility and clinical manifestations. (PubMed id 16581430)1, 4, 9 El-Shabrawi Y....Hermann J. (Ophthalmology 2006)
    310. Genetic susceptibility to ulcerative colitis in the Chinese Han ethnic population: association with TNF polymorphisms. (PubMed id 16863613)1, 4, 9 Cao Q....Si J.M. (Chin. Med. J. 2006)
    311. Lack of association between TNFalpha gene polymorphism at position -308 and risk of acute rheumatic fever in Turkish patients. (PubMed id 16467041)1, 4, 9 Berdeli A....Aydin H.H. (Scand. J. Rheumatol. 2006)
    312. Lack of association with TNF-alpha-308 promoter polymorphism in patients with vitiligo. (PubMed id 16691430)1, 4, 9 Yazici A.C....Tursen U. (Arch. Dermatol. Res. 2006)
    313. Autoimmunity and tuberculosis. Opposite association with TNF polymorphism. (PubMed id 15693080)1, 4, 9 Correa P.A....Anaya J.M. (J. Rheumatol. 2005)
    314. Association of tumour necrosis factor alpha variants with the CF pulmonary phenotype. (PubMed id 15790988)1, 4, 9 Yarden J....Cuppens H. (Thorax 2005)
    315. Lack of association between TNF-308 polymorphism and the clinical and immunological characteristics of systemic lupus erythematosus and primary SjAPgren's syndrome. (PubMed id 15971421)1, 4, 9 TobA^n G.J....Anaya J.M. (Clin. Exp. Rheumatol. 2005)
    316. Tumor necrosis factor-alpha promoter polymorphism in Mexican patients with Chagas' disease. (PubMed id 15790514)1, 4, 9 RodrA-guez-PAcrez J.M....Vargas-AlarcA^n G. (Immunol. Lett. 2005)
    317. Effect of cytokine gene polymorphism on histological activity index, viral load and response to treatment in patients with chronic hepatitis C genotype 3. (PubMed id 16425360)1, 4, 9 Abbas Z....Jafri W. (World J. Gastroenterol. 2005)
    318. Tumour necrosis factor gene polymorphisms and childhood wheezing. (PubMed id 16204594)1, 4, 9 Bilolikar H....Balfour-Lynn I.M. (Eur. Respir. J. 2005)
    319. Distinct tumour necrosis factor alpha, interferon gamma, interleukin 10, and cytotoxic T cell antigen 4 gene polymorphisms in disease occurrence and end stage renal disease in Wegener's granulomatosis. (PubMed id 15708894)1, 4, 9 Spriewald B.M....Kalden J.R. (Ann. Rheum. Dis. 2005)
    320. Association of the -159 CD14 gene polymorphism and lack of association of the -308 TNFA and Q551R IL-4RA polymorphisms with severe chronic periodontitis in Swedish Caucasians. (PubMed id 15842262)1, 4, 9 Donati M....Padyukov L. (J. Clin. Periodontol. 2005)
    321. Association of gene polymorphisms of tumour necrosis factor-alpha and interleukin-13 with chronic obstructive pulmonary disease in Han nationality in Beijing. (PubMed id 15820084)1, 4, 9 Jiang L....Yao W.Z. (Chin. Med. J. 2005)
    322. CD14 receptor polymorphism and Alzheimer's disease risk. (PubMed id 15854776)1, 4, 9 Combarros O....Berciano J. (Neurosci. Lett. 2005)
    323. [Study on the association between gestational diabetes mellitus and tumor necrosis factor-alpha gene polymorphism]. (PubMed id 16277898)1, 4, 9 Chang Y....Luo Y. (Zhonghua Fu Chan Ke Za Zhi 2005)
    324. [Recognition and study of susceptible gene to ankylosing spondylitis]. (PubMed id 15730950)1, 4, 9 Zhu X.Q....Yang Z. (Yi Chuan 2005)
    325. Polymorphisms of TNFalpha, IL1beta, and IL1RN genes in chronic obstructive pulmonary disease. (PubMed id 15766560)1, 4, 9 Hegab A.E....Sekizawa K. (Biochem. Biophys. Res. Commun. 2005)
    326. 1267 HSP70-2 polymorphism as a risk factor for carotid plaque rupture and cerebral ischaemia in old type 2 diabetes-atherosclerotic patients. (PubMed id 15992611)1, 4, 9 Giacconi R....Mocchegiani E. (Mech. Ageing Dev. 2005)
    327. Lack of association between the TNF alpha G -308 A promoter polymorphism and periodontal disease. (PubMed id 15142214)1, 4, 9 Folwaczny M....Folwaczny C. (J. Clin. Periodontol. 2004)
    328. [Genetic association of tumor necrosis factor (TNF)-alpha polymorphisms with primary biliary cirrhosis and autoimmune liver diseases in a Chinese population]. (PubMed id 15059302)1, 4, 9 Fan L.Y....Zhou L. (Zhonghua Gan Zang Bing Za Zhi 2004)
    329. An analysis of tumor necrosis factor alpha gene polymorphisms and haplotypes with natural clearance of hepatitis C virus infection. (PubMed id 15071492)1, 4, 9 Thio C.L....Thomas D.L. (Genes Immun. 2004)
    330. Influence of TNF gene polymorphism in patients with acute and fulminant hepatitis. (PubMed id 15565405)1, 4, 9 Tsuchiya N....Shiratori K. (J. Gastroenterol. 2004)
    331. Association of -238G/A polymorphism of tumor necrosis factor-alpha gene promoter region with outcomes of hepatitis B virus infection in Chinese Han population. (PubMed id 15188512)1, 4, 9 Lu L.P....Li H. (World J. Gastroenterol. 2004)
    332. TNF-alpha-308A allele, a possible severity risk factor of hemorrhagic manifestation in dengue fever patients. (PubMed id 15361124)1, 4, 9 FernA!ndez-Mestre M.T....Layrisse Z. (Tissue Antigens 2004)
    333. [Polymorphism of TNF-alpha in autoimmunity and tuberculosis]. (PubMed id 15495570)1, 4, 9 Correa P.A....Anaya J.M. (Biomedica 2004)
    334. Genetic risk factors for infection in patients with early rheumatoid arthritis. (PubMed id 15526004)1, 4, 9 Hughes L.B....Bridges S.L. (Genes Immun. 2004)
    335. Adverse outcomes after preterm labor are associated with tumor necrosis factor-alpha polymorphism -863, but not -308, in mother-infant pairs. (PubMed id 15507966)1, 4, 9 Amory J.H....Hitti J. (Am. J. Obstet. Gynecol. 2004)
    336. Ethnic differences in polymorphisms of tumor necrosis factor-alpha, interleukin-10, and transforming growth factor-beta1 genes in patients with chronic hepatitis C virus infection. (PubMed id 15100460)1, 4, 9 Zein N.N....Vidigal P.G. (Am. J. Trop. Med. Hyg. 2004)
    337. Tumor necrosis factor-alpha-308 promoter and p53 codon 72 gene polymorphisms in women with leiomyomas. (PubMed id 15474092)1, 4, 9 Hsieh Y.Y....Tsai C.H. (Fertil. Steril. 2004)
    338. Genetic contribution of tumor necrosis factor (TNF)-alpha gene promoter (-1031, -863 and -857) and TNF receptor 2 gene polymorphisms in endometriosis susceptibility. (PubMed id 15212671)1, 4, 9 Teramoto M....Honjo H. (Am. J. Reprod. Immunol. 2004)
    339. Genetic association of cutaneous neonatal lupus with HLA class II and tumor necrosis factor alpha: implications for pathogenesis. (PubMed id 15334474)1, 4, 9 Clancy R.M....Buyon J.P. (Arthritis Rheum. 2004)
    340. Tumor necrosis factor alpha promoter polymorphisms at position -308 in Taiwanese chronic hepatitis C patients treated with interferon-alpha. (PubMed id 12834858)1, 4, 9 Yu M.L....Chang W.Y. (Antiviral Res. 2003)
    341. Tumour necrosis factor-alpha polymorphism as one of the complex inherited factors in pemphigus. (PubMed id 14760938)1, 4, 9 Torzecka J.D....Kowalski M.L. (Mediators Inflamm. 2003)
    342. [Tumor necrosis factor-alpha and interleukin-10 gene polymorphisms in Korean patients with inflammatory bowel disease]. (PubMed id 14646574)1, 4, 9 Kim T.H....Song I.S. (Korean J Gastroenterol 2003)
    343. Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen. (PubMed id 12871600)1, 4, 9 Adams G.T....Kutlar A. (BMC Med. Genet. 2003)
    344. Relationship between the tumor necrosis factor alpha polymorphism and the serum C-reactive protein levels in inflammatory bowel disease. (PubMed id 12811429)1, 4, 9 Vatay A....FA1st G. (Immunogenetics 2003)
    345. Effect of TNF and LTA polymorphisms on biological markers of response to oxidative stimuli in coal miners: a model of gene-environment interaction. Tumour necrosis factor and lymphotoxin alpha. (PubMed id 12566517)1, 4, 9 Nadif R....Kauffmann F. (J. Med. Genet. 2003)
    346. Association between levels of TNF-alpha and TNF-alpha promoter -308 A/A polymorphism in children with Kawasaki disease. (PubMed id 12783130)1, 4, 9 Chien Y.H....Chiang B.L. (J. Formos. Med. Assoc. 2003)
    347. A tumor necrosis factor-alpha-inducible promoter variant of interferon-gamma accelerates CD4+ T cell depletion in human immunodeficiency virus-1-infected individuals. (PubMed id 12854077)1, 4, 9 An P....Winkler C.A. (J. Infect. Dis. 2003)
    348. Tumor necrosis factor-alpha levels and promoter polymorphism in patients with Kawasaki disease in Korea. (PubMed id 14703611)1, 4, 9 Ahn S.Y....Kim D.S. (Yonsei Med. J. 2003)
    349. Analysis of the modifying effects of SAA1, SAA2 and TNF-alpha gene polymorphisms on development of amyloidosis in FMF patients. (PubMed id 14696796)1, 4, 9 Yilmaz E....BakkaloA9lu A. (Turk. J. Pediatr. 2003)
    350. TNF-alpha -308A promoter polymorphism is associated with enhanced TNF-alpha production and inflammatory activity in Crohn's patients with fistulizing disease. (PubMed id 12809834)1, 4, 9 GonzA!lez S....LA^pez-Larrea C. (Am. J. Gastroenterol. 2003)
    351. Tumor necrosis factor-alpha promoter polymorphisms and the risk of rejection after liver transplantation: a case control analysis of 210 donor-recipient pairs. (PubMed id 12682890)1, 4, 9 Jazrawi S.F....Rosen H.R. (Liver Transpl. 2003)
    352. Tumor necrosis factor-alpha promoter gene polymorphism -308 and chorioamnionitis. (PubMed id 12850624)1, 4, 9 Simhan H.N....Caritis S.N. (Obstet Gynecol 2003)
    353. Decreased frequency of the tumor necrosis factor alpha -308 allele in Serbian patients with multiple sclerosis. (PubMed id 12824709)1, 4, 9 DruloviA8 J....Mostarica StojkoviA8 M. (Eur. Neurol. 2003)
    354. Association between novel GM-CSF gene polymorphisms and the frequency and severity of atopic dermatitis. (PubMed id 13679820)1, 4, 9 Rafatpanah H....Arkwright P.D. (J. Allergy Clin. Immunol. 2003)
    355. Association of IL2, TNFA, IL4 and IL10 Promoter Gene Polymorphisms with the Rate of Progression of the HIV Infection. (PubMed id 12687247)1, 4, 9 Smolnikova M.V. and Konenkov V.I. (Russ. J. Immunol. 2002)
    356. TNF alpha and LT alpha gene polymorphisms as additional markers of celiac disease susceptibility in a DQ2-positive population. (PubMed id 12439617)1, 4, 9 Garrote J.A....Blanco-QuirA^s A. (Immunogenetics 2002)
    357. The mutagenically separated polymerase chain reaction is a rapid and reliable method for genotyping of the tumour necrosis factor-alpha promoter polymorphism (-308 G/A). (PubMed id 11983212)1, 4, 9 SchlA1ter B....Assmann G. ( international journal of clinical chemistry 2002)
    358. Tumor necrosis factor-alpha +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease. (PubMed id 12537602)1, 4, 9 KA1AsA1kaycan M....Wouters E.F. (Respir. Res. 2002)
    359. Major histocompatibility complex class I chain related (MIC) A gene, TNFa microsatellite alleles and TNFB alleles in juvenile idiopathic arthritis patients from Latvia. (PubMed id 11975986)1, 4, 9 Nikitina Zake L....Sanjeevi C.B. (Hum. Immunol. 2002)
    360. Host defense and inflammatory gene polymorphisms are associated with outcomes after HLA-identical sibling bone marrow transplantation. (PubMed id 12393699)1, 4, 9 Rocha V....Gluckman E. (Blood 2002)
    361. Association of the TNF-alpha -308 G/A promoter polymorphism with insulin resistance in obesity. (PubMed id 12006640)1, 4, 9 Dalziel B....Caterson I.D. (Obes. Res. 2002)
    362. Association of a single nucleotide variant in the human tumour necrosis factor alpha promoter region with decreased bone mineral density. (PubMed id 12396374)1, 4, 9 Ota N....Emi M. (Ann. Hum. Biol. 2002)
    363. Cytokine gene polymorphisms in children successfully withdrawn from immunosuppression after liver transplantation. (PubMed id 11981433)1, 4, 9 Mazariegos G.V....Zeevi A. (Transplantation 2002)
    364. Profound bias in interferon-gamma and interleukin-6 allele frequencies in western Kenya, where severe malarial anemia is common in children. (PubMed id 12232842)1, 4, 9 Gourley I.S....Duffy P.E. (J. Infect. Dis. 2002)
    365. Lack of association between atopic asthma and the tumor necrosis factor alpha-308 gene polymorphism in a Czech population. (PubMed id 12530118)1, 4, 9 BuckovA! D....VA!cha J. (amp 2002)
    366. Polymorphisms in the TNF-alpha and TNF-receptor genes in patients with coronary artery disease. (PubMed id 11737221)1, 4, 9 Allen R.A....Pirmohamed M. (Eur. J. Clin. Invest. 2001)
    367. Septic shock and respiratory failure in community-acquired pneumonia have different TNF polymorphism associations. (PubMed id 11401880)1, 4, 9 Waterer G.W....Wunderink R.G. (Am. J. Respir. Crit. Care Med. 2001)
    368. Association between -G308A tumor necrosis factor alpha gene polymorphism and schizophrenia. (PubMed id 11244489)1, 4, 9 Boin F....Gennarelli M. (Mol. Psychiatry 2001)
    369. TNFalpha promoter region gene polymorphisms in carbamazepine-hypersensitive patients. (PubMed id 11294926)1, 4, 9 Pirmohamed M....Park B.K. (Neurology 2001)
    370. Increased frequency of the tumor necrosis factor-alpha-308 A allele in adults with human immunodeficiency virus dementia. (PubMed id 11506397)1, 4, 9 Quasney M.W....McArthur J. (Ann. Neurol. 2001)
    371. Tumor necrosis factor alpha promoter polymorphisms influence the phenotypic expression of hereditary hemochromatosis. (PubMed id 11389006)1, 4, 9 Fargion S....Fiorelli G. (Blood 2001)
    372. Tumor necrosis factor-alpha -308 promoter gene polymorphism and increased tumor necrosis factor serum bioactivity in farmer's lung patients. (PubMed id 11179110)1, 4, 9 Schaaf B.M....Zabel P. (Am. J. Respir. Crit. Care Med. 2001)
    373. Influence of tumor necrosis factor-alpha gene-308 polymorphism on the development of coronary vasculopathy after cardiac transplantation. (PubMed id 11744409)1, 4, 9 Densem C.G....Brooks N.H. (J. Heart Lung Transplant. 2001)
    374. Polymorphisms in tumour necrosis factor alpha, interleukin-10 and transforming growth factor beta1 genes and end-stage liver disease. (PubMed id 11192323)1, 4, 9 Bathgate A.J....Hutchinson I.V. (amp 2000)
    375. Contribution of TNF-alpha and IL-10 gene polymorphisms to graft-versus-host disease following allo-hematopoietic stem cell transplantation. (PubMed id 11223972)1, 4, 9 Takahashi H....Koike T. (Bone Marrow Transplant. 2000)
    376. Plasma interleukin-10:Tumor necrosis factor (TNF)-alpha ratio is associated with TNF promoter variants and predicts malarial complications. (PubMed id 11023485)1, 4, 9 May J....Kremsner P.G. (J. Infect. Dis. 2000)
    377. Lack of association between promoter polymorphism of the tumor necrosis factor-alpha gene and psoriatic arthritis in Japanese patients. (PubMed id 11121160)1, 4, 9 Hamamoto Y....Muto M. (J. Invest. Dermatol. 2000)
    378. Tumor necrosis factor gene polymorphisms in patients with cirrhosis from chronic hepatitis C virus infection. (PubMed id 11196686)1, 4, 9 Yee L.J....van Leeuwen D.J. (Genes Immun. 2000)
    379. Association of genotypes affecting the expression of interleukin-1beta or interleukin-1 receptor antagonist with osteoarthritis. (PubMed id 11083263)1, 4, 9 Moos V....MA1ller B. (Arthritis Rheum. 2000)
    380. Common variations in the genes encoding C-reactive protein, tumor necrosis factor-alpha, and interleukin-6, and the risk of clinical diabetes in the Women's Health Initiative Observational Study. (PubMed id 21149504)1, 4 Chan K.H....Liu S. (Clin. Chem. 2011)
    381. Hodgkin disease risk: role of genetic polymorphisms and gene-gene interactions in inflammation pathway genes. (PubMed id 21061265)1, 4 Monroy C.M....El-Zein R.A. (Mol. Carcinog. 2011)
    382. Association of haplotypes of inflammation-related genes with gastric preneoplastic lesions in African Americans and Caucasians. (PubMed id 20473875)1, 4 Zabaleta J....Ochoa A.C. (Int. J. Cancer 2011)
    383. TNF-I+ gene polymorphisms and excessive daytime sleepiness in pediatric obstructive sleep apnea. (PubMed id 20846669)1, 4 Khalyfa A....Gozal D. (J. Pediatr. 2011)
    384. Possible effect of gene polymorphisms on the release of TNFI+ and IL1 cytokines in coal workers' pneumoconiosis. (PubMed id 20005085)1, 4 Ates I....Karakaya A. (Exp. Toxicol. Pathol. 2011)
    385. TNF-308 gene polymorphism is associated with COPD risk among Asians: meta-analysis of data for 6,118 subjects. (PubMed id 20364405)1, 4 Zhan P....Song Y. (Mol. Biol. Rep. 2011)
    386. Cytokine polymorphisms in Th1/Th2 pathway genes, body mass index, and risk of non-Hodgkin lymphoma. (PubMed id 20952689)1, 4 Chen Y....Zhang Y. (Blood 2011)
    387. Association of interferon-gamma, interleukin-10, and tumor necrosis factor-alpha gene polymorphisms with occurrence and severity of Eales' disease. (PubMed id 20720222)1, 4 Sen A....Bhattacharya B. (amp 2011)
    388. Interaction between tumor necrosis factor-I+ gene -308G/A promoter and leptin receptor gene Lys656Asn single-nucleotide polymorphisms: effect on serum leptin concentrations. (PubMed id 20814201)1, 4 de Luis D.A....Romero E. (amp 2010)
    389. Interleukin-1beta and -10 polymorphisms influence erosive reflux esophagitis and gastritis in Taiwanese patients. (PubMed id 20659236)1, 4 Cheng H.H....Wang W.C. (J. Gastroenterol. Hepatol. 2010)
    390. Influence of tumour necrosis factor-I+ polymorphism-308 and atopy on irritant contact dermatitis in healthcare workers. (PubMed id 20731689)1, 4 Davis J.A....Hoath S.B. (Contact Derm. 2010)
    391. IL1RN VNTR and IL2-330 polymorphic genes are independently associated with chronic immune thrombocytopenia. (PubMed id 20626741)1, 4 Rocha A.M....Queiroz D.M. (Br. J. Haematol. 2010)
    392. Dengue hemorrhagic fever is associated with polymorphisms in JAK1. (PubMed id 20588308)1, 4 Silva L.K....Teixeira M.G. (Eur. J. Hum. Genet. 2010)
    393. Single nucleotide polymorphisms in inflammatory genes and the risk of early onset of lone atrial fibrillation. (PubMed id 20490891)1, 4 Henningsen K.M....Svendsen J.H. (Inflamm. Res. 2010)
    394. Cytokine gene polymorphisms in irritable bowel syndrome in Indian population--a pilot case control study. (PubMed id 20860222)1, 4 Santhosh S....Kurian G. (Trop Gastroenterol 2010)
    395. Association of the tumor necrosis factor-alpha -308 G/A polymorphism with nasal polyposis. (PubMed id 20012441)1, 4 Batikhan H....Gerceker M. (Eur Arch Otorhinolaryngol 2010)
    396. Lack of effect of tumor necrosis factor-alpha -308 G/A polymorphism on severity of liver fibrosis in Tunisian hepatitis C virus (HCV)-infected patients. (PubMed id 20537485)1, 4 Bouzgarrou N....Chouchane L. (Gastroenterol. Clin. Biol. 2010)
    397. Influence of polygenetic polymorphisms on the susceptibility to non-alcoholic fatty liver disease of Chinese people. (PubMed id 20492333)1, 4 Zhou Y.J....Huang H.L. (J. Gastroenterol. Hepatol. 2010)
    398. Polymorphisms in inflammatory genes, plasma antioxidants, and prostate cancer risk. (PubMed id 20431935)1, 4 Zhang J....Kadlubar F.F. (amp 2010)
    399. Study of TNFalpha -308G/A and IL6 -174G/C polymorphisms in type 2 diabetes and obesity risk in the Tunisian population. (PubMed id 20132806)1, 4 Bouhaha R....Vaxillaire M. (Clin. Biochem. 2010)
    400. Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility &quot;hot-spot&quot;. (PubMed id 20628624)1, 4 Johnatty S.E.... . (PLoS Genet. 2010)
    401. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    402. Association of -308G/A polymorphism in the tumor necrosis factor-alpha gene promoter with susceptibility to development of hantavirus cardiopulmonary syndrome in the RibeirALo Preto region, Brazil. (PubMed id 20372945)1, 4 Borges A.A....Figueiredo L.T. (Arch. Virol. 2010)
    403. Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. (PubMed id 20587610)1, 4 Ucisik-Akkaya E....Dorak M.T. (Mol. Hum. Reprod. 2010)
    404. Association of tumor necrosis factor-alpha gene promoter polymorphisms with acute viral hepatitis in the Indian population. (PubMed id 19390969)1, 4 Singhal S....Kar P. (Dig. Dis. Sci. 2010)
    405. Cytokines genes polymorphisms and risk of multiple sclerosis. (PubMed id 20228669)1, 4 Izad M....Keramatipour M. (Am. J. Med. Sci. 2010)
    406. A systematic review and meta-analysis of tumor necrosis factor I+-308 polymorphism and Kawasaki disease. (PubMed id 20202153)1, 4 Arj-Ong S....Attia J. (Pediatr Int 2010)
    407. Associations of the IL-1 and TNF gene polymorphisms in the susceptibility to duodenal ulcer disease in Chinese Han population. (PubMed id 19804405)1, 4 Mei Q....Hu Y.M. (Int. J. Immunogenet. 2010)
    408. The rs1800629 polymorphism in the TNF gene interacts with physical activity on the changes in C-reactive protein levels in the Finnish Diabetes Prevention Study. (PubMed id 20361391)1, 4 KilpelAoinen T.O....Tuomilehto J. (amp 2010)
    409. TNF polymorphisms in patients with BehAset disease: a meta-analysis. (PubMed id 20470944)1, 4 Touma Z....Arayssi T. (Arch. Med. Res. 2010)
    410. Cytokine genetic polymorphisms and susceptibility to Kawasaki disease in Taiwanese children. (PubMed id 21048327)1, 4 Weng K.P....Ger L.P. (Circ. J. 2010)
    411. Genetic evaluation of the TNF-I+ -238G&gt;A and -308G&gt;A promoter polymorphisms in Croatian patients with type I diabetes. (PubMed id 20849900)1, 4 Korolija M....HadA3ija M.P. (Hum. Immunol. 2010)
    412. Common single nucleotide polymorphisms in immunoregulatory genes and multiple myeloma risk among women in Connecticut. (PubMed id 20568250)1, 4 Lee K.M....Lan Q. (Am. J. Hematol. 2010)
    413. Combining genetic markers and clinical risk factors improves the risk assessment of impaired glucose metabolism. (PubMed id 20384434)1, 4 Ruchat S.M....PAcrusse L. (Ann. Med. 2010)
    414. Clinical relevance of 13 cytokine gene polymorphisms in Chinese major trauma patients. (PubMed id 20217044)1, 4 Gu W....Jiang J.X. (Intensive Care Med 2010)
    415. Association of combined maternal-fetal TNF-alpha gene G308A genotypes with preterm delivery: a gene-gene interaction study. (PubMed id 20224765)1, 4 Liang M....Chen D. (amp 2010)
    416. Cytokine gene polymorphisms in sarcoidosis. (PubMed id 21086908)1, 4 Vasakova M....Striz I. (Sarcoidosis Vasc Diffuse Lung Dis 2010)
    417. Pathway genetic load allows simultaneous evaluation of multiple genetic associations. (PubMed id 20381257)1, 4 Huebinger R.M....Barber R.C. (Burns 2010)
    418. Helicobacter pylori infection and cytokine gene polymorphisms in Uzbeks. (PubMed id 20942272)1, 4 Abdiev S....Hamajima N. (Nagoya J Med Sci 2010)
    419. Cystic fibrosis conductance regulator, tumor necrosis factor, interferon alpha-10, interferon alpha-17, and interferon gamma genotyping as potential risk markers in pulmonary sarcoidosis pathogenesis in Greek patients. (PubMed id 20722470)1, 4 Makrythanasis P....Kanavakis E. (Genet Test Mol Biomarkers 2010)
    420. G protein beta3 subunit, interleukin-10, and tumor necrosis factor-alpha gene polymorphisms in Koreans with irritable bowel syndrome. (PubMed id 20337945)1, 4 Lee H.J....Jin C.J. (Neurogastroenterol. Motil. 2010)
    421. Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population. (PubMed id 20485444)1, 4 Wang Y....Huang W. (J. Hum. Genet. 2010)
    422. TNF-alpha -308G&gt;A and IL-6 -174G&gt;C polymorphisms in Tunisian patients with coronary artery disease. (PubMed id 20493832)1, 4 Ghazouani L....Mahjoub T. (Clin. Biochem. 2010)
    423. Association of candidate susceptible loci with chronic infection with hepatitis B virus in a Chinese population. (PubMed id 20087947)1, 4 Chen D.Q....Zheng B.J. (J. Med. Virol. 2010)
    424. Relationship between cytokine gene single nucleotide polymorphisms and symptom burden and quality of life in lung cancer survivors. (PubMed id 20564140)1, 4 Rausch S.M....Yang P. (Cancer 2010)
    425. Nontuberculous mycobacterial cervicofacial lymphadenitis in children from the multicenter, randomized, controlled trial in The Netherlands: relevance of polymorphisms in candidate host immunity genes. (PubMed id 20399512)1, 4 Haverkamp M.H....van Dissel J.T. (Int. J. Pediatr. Otorhinolaryngol. 2010)
    426. Association of the TNF-{alpha}-C-857T polymorphism with resistance to the cholesterol-lowering effect of HMG-CoA reductase inhibitors in type 2 diabetic subjects. (PubMed id 20007938)1, 4 Takahashi T....Satoh J. (Diabetes Care 2010)
    427. Additive effect of polymorphisms in the IL-6, LTA, and TNF-{alpha} genes and plasma fatty acid level modulate risk for the metabolic syndrome and its components. (PubMed id 20080841)1, 4 Phillips C.M....Roche H.M. (J. Clin. Endocrinol. Metab. 2010)
    428. The cancer anorexia/weight loss syndrome: exploring associations with single nucleotide polymorphisms (SNPs) of inflammatory cytokines in patients with non-small cell lung cancer. (PubMed id 20012999)1, 4 Jatoi A....Yang P. (Support Care Cancer 2010)
    429. Association of TNF-alpha gene with spontaneous deep intracerebral hemorrhage in the Taiwan population: a case control study. (PubMed id 20534169)1, 4 Chen Y.C....Chen C.M. (BMC Neurol 2010)
    430. Tumor necrosis factor (TNF) and lymphotoxin-alpha (LTA) polymorphisms and risk of non-Hodgkin lymphoma in the InterLymph Consortium. (PubMed id 20047977)1, 4 Skibola C.F....Wang S.S. (Am. J. Epidemiol. 2010)
    431. Independent predictive roles of eotaxin Ala23Thr, paraoxonase 2 Ser311Cys and beta-adrenergic receptor Trp64Arg polymorphisms on cardiac disease in Type 2 Diabetes--an 8-year prospective cohort analysis of 1297 patients. (PubMed id 20536507)1, 4 Wang Y....Chan J.C. (Diabet. Med. 2010)
    432. Association of IL1A, IL1B, and TNF gene polymorphisms with chronic rhinosinusitis with and without nasal polyposis: A replication study. (PubMed id 20157068)1, 4 Mfuna Endam L....Desrosiers M. (amp 2010)
    433. Cytokine polymorphism in noninfectious uveitis. (PubMed id 20335604)1, 4 Atan D....Churchill A.J. (amp 2010)
    434. Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. (PubMed id 20503287)1, 4 Schuurhof A....Janssen R. (Pediatr. Pulmonol. 2010)
    435. Genetic susceptibility to distinct bladder cancer subphenotypes. (PubMed id 19692168)1, 4 Guey L.T....Malats N. (Eur. Urol. 2010)
    436. Interaction of immunological genes on chromosome 2q33 and IFNG in susceptibility to cervical cancer. (PubMed id 19959217)1, 4 Ivansson E.L....Gyllensten U.B. (Gynecol. Oncol. 2010)
    437. Association between tumor necrosis factor-alpha (-308Ga89A and -238Ga89A) polymorphisms and homocysteine levels in patients with ischemic strokes and silent brain infarctions. (PubMed id 20798494)1, 4 Kim O.J....Kim N.K. (Cerebrovasc. Dis. 2010)
    438. Genetic variation in tumor necrosis factor and risk of diffuse large B-cell lymphoma and follicular lymphoma: differences between subgroups in Swedish patients. (PubMed id 20578820)1, 4 Thunberg U....Berglund M. (amp 2010)
    439. The association between TNF-alpha promoter polymorphisms and ankylosing spondylitis: a meta-analysis. (PubMed id 20535510)1, 4 Li B....Li H. (Clin. Rheumatol. 2010)
    440. Polymorphisms of the TNF-alpha and ACE genes, and renal scarring in infants with urinary tract infection. (PubMed id 20022049)1, 4 Savvidou A....Galanakis E. (J. Urol. 2010)
    441. Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994. (PubMed id 21054877)1, 4 Ned R.M....Dowling N.F. (BMC Med. Genet. 2010)
    442. Association of tumor necrosis factor-alpha-863C/A gene polymorphism with chronic obstructive pulmonary disease. (PubMed id 20352242)1, 4 Chen Y.C....Lin M.C. (Lung 2010)
    443. Analyses of functional IL10 and TNF-I+ genotypes in BehAset's syndrome. (PubMed id 20191386)1, 4 AteA9 O....Topal-SarA+kaya A. (Mol. Biol. Rep. 2010)
    444. Frequencies of polymorphisms in cytokines, neurotransmitters and adrenergic receptors in patients with complex regional pain syndrome type I after distal radial fracture. (PubMed id 20173430)1, 4 Herlyn P....Gradl G. (Clin J Pain 2010)
    445. The role of functional polymorphisms of the TNF-alpha gene promoter in the risk of ischemic stroke in Chinese Han and Uyghur populations: Two case-control studies. (PubMed id 20493182)1, 4 Tong Y....Cheng J. ( international journal of clinical chemistry 2010)
    446. Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease. (PubMed id 20346360)1, 4 Roberts K.E....Fallon M.B. (Gastroenterology 2010)
    447. Polymorphisms in the BRCA1 and ABCB1 genes modulate menopausal hormone therapy associated breast cancer risk in postmenopausal women. (PubMed id 19672706)1, 4 (Breast Cancer Res. Treat. 2010)
    448. Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus. (PubMed id 20662065)1, 4 Clancy R.M....Buyon J.P. (Arthritis Rheum. 2010)
    449. Large-scale association analysis of TNF/LTA gene region polymorphisms in type 2 diabetes. (PubMed id 20459604)1, 4 Boraska V....Zeggini E. (BMC Med. Genet. 2010)
    450. Carriage of a tumor necrosis factor polymorphism amplifies the cytotoxic T-lymphocyte antigen 4 attributed risk of primary biliary cirrhosis: evidence for a gene-gene interaction. (PubMed id 20578265)1, 4 Juran B.D....Lazaridis K.N. (Hepatology 2010)
    451. A candidate gene study of obstructive sleep apnea in European Americans and African Americans. (PubMed id 20538960)1, 4 Larkin E.K....Redline S. (Am. J. Respir. Crit. Care Med. 2010)
    452. Polymorphisms in tumor necrosis factor and lymphotoxin A in tuberculosis without and with response to treatment. (PubMed id 20180006)1, 4 GarcA-a-Elorriaga G....GonzA!lez-Bonilla C. (Inflammation 2010)
    453. Polymorphisms in cytokine genes and serum cytokine levels among New Mexican women with and without breast cancer. (PubMed id 20418110)1, 4 Erdei E....Berwick M. (Cytokine 2010)
    454. Metagenomic study of single-nucleotide polymorphism within candidate genes associated with type 2 diabetes in an Indian population. (PubMed id 20967696)1, 4 Mukhopadhyaya P.N....Mutha A. (Genet. Mol. Res. 2010)
    455. Tumor necrosis factor-alpha promoter variants and iron phenotypes in 785 hemochromatosis and iron overload screening (HEIRS) study participants. (PubMed id 20178892)1, 4 Acton R.T....Eckfeldt J.H. (amp 2010)
    456. A Large-scale genetic association study of esophageal adenocarcinoma risk. (PubMed id 20453000)1, 4 Liu C.Y....Christiani D.C. (Carcinogenesis 2010)
    457. [Analysis of linkage and association of alleles of proinflammatory cytokines genes IL-6, IFNg and TNF with multiple sclerosis using transmission disequilibrium test (TDT)]. (PubMed id 21090238)1, 4 Makarycheva O.I.u....Favorova O.O. (Mol. Biol. (Mosk.) 2010)
    458. Linkage of large-vessel carotid atherosclerotic stroke to inflammatory genes via a systematic screen. (PubMed id 20536609)1, 4 Belfer I....DeGraba T.J. (Int J Stroke 2010)
    459. A strong genetic association between the tumor necrosis factor locus and proliferative vitreoretinopathy: the retina 4 project. (PubMed id 20663564)1, 4 Rojas J....Carracedo A. (Ophthalmology 2010)
    460. Interaction between early maternal smoking and variants in TNF and GSTP1 in childhood wheezing. (PubMed id 20210814)1, 4 Panasevich S....MelAcn E. (Clin. Exp. Allergy 2010)
    461. The association of innate immune response gene polymorphisms and puerperal group A streptococcal sepsis. (PubMed id 20207250)1, 4 Davis S.M....Silver R.M. (Am. J. Obstet. Gynecol. 2010)
    462. Genetic association between TNF-alpha -308 G&gt;A polymorphism and longitudinal weight change during clozapine treatment. (PubMed id 20521320)1, 4 Wang Y.C....Liou Y.J. (Hum Psychopharmacol 2010)
    463. Polymorphisms in tumour necrosis factor alpha (TNFalpha) gene in patients with acute pancreatitis. (PubMed id 20396411)1, 4 Ozhan G....Alpertunga B. (Mediators Inflamm. 2010)
    464. Genetic variability in the severity and outcome of community-acquired pneumonia. (PubMed id 19900796)1, 4 SolAc-ViolA!n J....Rodriguez-Gallego C. (Respir Med 2010)
    465. Role of polymorphic variants as genetic modulators of infection in neonatal sepsis. (PubMed id 20463618)1, 4 Abu-Maziad A....Murray J.C. (Pediatr. Res. 2010)
    466. Cardiovascular disease in kidney transplant recipients: the prognostic value of inflammatory cytokine genotypes. (PubMed id 20061995)1, 4 La Manna G....Stefoni S. (Transplantation 2010)
    467. The -308 (G/A) single nucleotide polymorphism in the TNF-alpha gene and the risk of major depression in the elderly. (PubMed id 19618378)1, 4 Cerri A.P....Annoni G. (Int J Geriatr Psychiatry 2010)
    468. Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease. (PubMed id 20014019)1, 4 Dubinsky M.C....Rotter J.I. (Inflamm. Bowel Dis. 2010)
    469. Tumor necrosis factor-alpha polymorphisms and expression in Guillain-BarrAc syndrome. (PubMed id 20600447)1, 4 Prasad K.N....Paliwal V.K. (Hum. Immunol. 2010)
    470. Tumour necrosis factor alpha -308G-&gt;A polymorphism is not associated with response to TNFalpha blockers in Caucasian patients with rheumatoid arthritis: systematic review and meta-analysis. (PubMed id 19966089)1, 4 Pavy S....Coenen M.J. (Ann. Rheum. Dis. 2010)
    471. Tumor necrosis factor-{alpha} rs361525 polymorphism is associated with increased local production and downstream inflammation in chronic obstructive pulmonary disease. (PubMed id 20299531)1, 4 Sapey E....Stockley R.A. (Am. J. Respir. Crit. Care Med. 2010)
    472. Association between tumor necrosis factor-alpha promoter -308 A/G polymorphism and susceptibility to sepsis and sepsis mortality: a systematic review and meta-analysis. (PubMed id 19789454)1, 4 Teuffel O....Sung L. (Crit. Care Med. 2010)
    473. Tumor necrosis factor-alpha polymorphisms in women with idiopathic recurrent miscarriage. (PubMed id 20106534)1, 4 Finan R.R....Almawi W.Y. (J. Reprod. Immunol. 2010)
    474. Replication of genetic association studies in asthma and related phenotypes. (PubMed id 20395963)1, 4 Undarmaa S....Suzuki Y. (J. Hum. Genet. 2010)
    475. Tumor necrosis factor alpha -C850T polymorphism is significantly associated with endometriosis in Asian Indian women. (PubMed id 19394608)1, 4 Lakshmi K.V....Hasan Q. (Fertil. Steril. 2010)
    476. Association of Helicobacter pylori infection with reduced risk for esophageal cancer is independent of environmental and genetic modifiers. (PubMed id 20399210)1, 4 Whiteman D.C....Webb P.M. (Gastroenterology 2010)
    477. IL-10 and TNF-alpha promoter polymorphisms in susceptibility to systemic lupus erythematosus in Taiwan. (PubMed id 20576226)1, 4 Lin Y.J....Tsai F.J. (Clin. Exp. Rheumatol. 2010)
    478. Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism. (PubMed id 20603037)1, 4 Beckers M.M....Biesma D.H. (Eur. J. Intern. Med. 2010)
    479. Etanercept reduces matrix metalloproteinase-9 level in children with polyarticular juvenile idiopathic arthritis and TNF-alpha-308GG genotype. (PubMed id 20596903)1, 4 Basic J....Veljkovic A. (J. Physiol. Biochem. 2010)
    480. Tumor necrosis factor alpha, interleukin-6 and interleukin-10 polymorphisms in preeclampsia. (PubMed id 20178529)1, 4 Vural P....Eroglu H. (J. Obstet. Gynaecol. Res. 2010)
    481. Gene polymorphisms in association with emerging cardiovascular risk markers in adult women. (PubMed id 20078877)1, 4 Fan A.Z....Mokdad A.H. (BMC Med. Genet. 2010)
    482. Association of longevity with IL-10 -1082 G/A and TNF-alpha-308 G/A polymorphisms. (PubMed id 20518833)1, 4 Khabour O.F. and Barnawi J.M. (Int. J. Immunogenet. 2010)
    483. Interleukin 10 and tumor necrosis factor-alpha genotypes in rheumatoid arthritis--association with clinical response to glucocorticoids. (PubMed id 20080912)1, 4 de Paz B....SuA!rez A. (J. Rheumatol. 2010)
    484. Proinflammatory cytokine gene polymorphisms in irritable bowel syndrome. (PubMed id 19844779)1, 4 Barkhordari E....Amirzargar A.A. (J. Clin. Immunol. 2010)
    485. Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring. (PubMed id 20459687)1, 4 Eid N.A....Ibrahim M.E. (Malar. J. 2010)
    486. G308A polymorphism of TNF-alpha gene is associated with insulin resistance and histological changes in non alcoholic fatty liver disease patients. (PubMed id 21057163)1, 4 Aller R....Velasco M.C. (Ann Hepatol 2010)
    487. Association between anthropometric measures of obesity, metabolic disturbances and polymorphism G-308A of the tumor necrosis factor-alpha gene in children. (PubMed id 21147642)1, 4 Pyrzak B....Kucharska A.M. (Eur. J. Med. Res. 2010)
    488. Human leukocyte antigen (HLA) and single nucleotide polymorphisms (SNPs) tumor necrosis factor (TNF)-alpha -238 and -308 as genetic markers of susceptibility to psoriasis and severity of the disease in a long-term follow-up Brazilian study. (PubMed id 20931685)1, 4 MagalhALes R.F....Kraemer M.H. (Int. J. Dermatol. 2010)
    489. Tumor necrosis factor alpha (TNF-alpha) polymorphisms in Chinese patients with Graves' disease. (PubMed id 19732761)1, 4 Gu L.Q....Zhao Y.J. (Clin. Biochem. 2010)
    490. Polymorphisms in genes involved in autoimmune disease and the risk of FVIII inhibitor development in Italian patients with haemophilia A. (PubMed id 20015215)1, 4 Bafunno V....Margaglione M. (Haemophilia 2010)
    491. The COPD genetic association compendium: a comprehensive online database of COPD genetic associations. (PubMed id 19933216)1, 4 Castaldi P.J....Trikalinos T.A. (Hum. Mol. Genet. 2010)
    492. IL-2 and IL-10 gene polymorphisms are associated with respiratory tract infection and may modulate the effect of vitamin E on lower respiratory tract infections in elderly nursing home residents. (PubMed id 20484443)1, 4 Belisle S.E....Meydani S.N. (Am. J. Clin. Nutr. 2010)
    493. Tumour necrosis factor 308 polymorphisms and hepatocellular carcinoma risk: a meta-analysis. (PubMed id 21033253)1, 4 Guo Y.M....Shen X.Z. (Hepatogastroenterology 2010)
    494. A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). (PubMed id 20673868)1, 4 Romero R....Menon R. (Am. J. Obstet. Gynecol. 2010)
    495. TNFalpha -308 G/A polymorphism is associated with breast cancer risk: a meta-analysis involving 10,184 cases and 12,911 controls. (PubMed id 20035378)1, 4 Fang F....Yu L. (Breast Cancer Res. Treat. 2010)
    496. A study of the TNF/LTA/LTB locus and susceptibility to severe malaria in highland papuan children and adults. (PubMed id 21029472)1, 4 Randall L.M....Engwerda C.R. (Malar. J. 2010)
    497. Tumor necrosis factor-I+ gene polymorphisms in age-related macular degeneration. (PubMed id 21060270)1, 4 Wan L....Lin J.M. (Retina (Philadelphia, Pa.) 2010)
    498. Candidate gene study of susceptibility to cutaneous leishmaniasis in Sri Lanka. (PubMed id 20214763)1, 4 Samaranayake T.N....Dissanayake V.H. (amp 2010)
    499. Associations between tumor necrosis factor-alpha (TNF-alpha) -308 and -238 G/A polymorphisms and shared epitope status and responsiveness to TNF-alpha blockers in rheumatoid arthritis: a metaanalysis update. (PubMed id 20194454)1, 4 Lee Y.H....Song G.G. (J. Rheumatol. 2010)
    500. The interleukin 6 -174 C/C genotype predicts greater rhinovirus illness. (PubMed id 20001857)1, 4 Doyle W.J....Cohen S. (J. Infect. Dis. 2010)
    501. A multiplex MALDI-TOF MS approach facilitates genotyping of DNA from formalin-fixed paraffin-embedded tumour specimens. (PubMed id 20802378)1, 4 Horn H....Schaeffeler E. (Pharmacogenet. Genomics 2010)
    502. Influence of CRP, IL6, and TNFA gene polymorphisms on circulating levels of C-reactive protein in Mexican adolescents. (PubMed id 21044752)1, 4 Mendoza-Carrera F....SA!nchez-Corona J. (Arch. Med. Res. 2010)
    503. Tumor necrosis factor-alpha gene -308 G/A polymorphism modulates the relationship between dietary fat intake, serum lipids, and obesity risk in black South African women. (PubMed id 20335630)1, 4 Joffe Y.T....Goedecke J.H. (J. Nutr. 2010)
    504. Association of tumor necrosis factor-alpha polymorphisms with susceptibility and clinical outcomes of rheumatic heart disease. (PubMed id 20563362)1, 4 Mohamed A.A....Ammar R.I. (Saudi Med J 2010)
    505. A study of TNF-alpha-238 and -308 polymorphisms with different outcomes of persistent hepatitis B virus infection in China. (PubMed id 21080879)1, 4 Wang B....Zeng Z. (Pathology 2010)
    506. Tumour necrosis factor-alpha gene polymorphisms in asbestos-induced diseases. (PubMed id 20486865)1, 4 Helmig S....Schneider J. (Biomarkers 2010)
    507. Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. (PubMed id 20331378)1, 4 Mosbruger T.L....Thio C.L. (J. Infect. Dis. 2010)
    508. [Analysis of polymorphism of three positions of promoter region of TNF- gene in patients with ischemic heart disease, unstable angina and myocardial infarction]. (PubMed id 20146672)1, 4 Shevchenko A.V....Voevoda M.I. (Kardiologiia 2010)
    509. Human leukocyte antigen (HLA) A1-B8-DR3 (8.1) haplotype, tumor necrosis factor (TNF) G-308A, and risk of non-Hodgkin lymphoma. (PubMed id 20147981)1, 4 Abdou A.M....Wang S.S. (Leukemia 2010)
    510. TNF-alpha promoter polymorphisms in multiple sclerosis: no association with -308 and -238 alleles, but the -857 alleles in associated with the disease in Turkish patients. (PubMed id 20082645)1, 4 Akcali A....Neyal M. (Int. J. Immunogenet. 2010)
    511. TNF-alpha and TNF-beta gene polymorphisms in Polish patients with sarcoidosis. Connection with the susceptibility and prognosis. (PubMed id 21319595)1, 4 Kieszko R....Milanowski J. (Sarcoidosis Vasc Diffuse Lung Dis 2010)
    512. Characterization of tumor necrosis factor-I+ block haplotypes associated with susceptibility to chronic venous leg ulcers in Caucasian patients. (PubMed id 20854863)1, 4 Tan J.H....Wallace H.J. (Hum. Immunol. 2010)
    513. Study on association between genetic polymorphisms of haem oxygenase-1, tumour necrosis factor, cadmium exposure and malaria pathogenicity and severity. (PubMed id 20846452)1, 4 Kuesap J....Na-Bangchang K. (Malar. J. 2010)
    514. Host genetics and outcome in meningococcal disease: a systematic review and meta-analysis. (PubMed id 20334849)1, 4 Brouwer M.C....van de Beek D. (Lancet Infect Dis 2010)
    515. Obesity-dependent association of TNF-LTA locus with type 2 diabetes in North Indians. (PubMed id 20177654)1, 4 Mahajan A....Bharadwaj D. (J. Mol. Med. 2010)
    516. A placebo-controlled, double-blind trial of infliximab for cancer-associated weight loss in elderly and/or poor performance non-small cell lung cancer patients (N01C9). (PubMed id 19665818)1, 4 Jatoi A....Loprinzi C.L. (Lung Cancer 2010)
    517. Interleukin 10 polymorphisms differentially influence the risk of gastric cancer in East Asians and Caucasians. (PubMed id 20363151)1, 4 Won H.H....Lee K.A. (Cytokine 2010)
    518. Influence of G308A polymorphism of tumor necrosis factor alpha gene on surgical results of biliopancreatic diversion. (PubMed id 18566867)1, 4 de Luis D.A....Martin T. (Obes Surg 2010)
    519. Effect of TNF-alpha genetic variants and CCR5 Delta 32 on the vulnerability to HIV-1 infection and disease progression in Caucasian Spaniards. (PubMed id 20420684)1, 4 Veloso S....Vidal F. (BMC Med. Genet. 2010)
    520. Association of polymorphisms of tumor necrosis factor and tumor protein p53 with primary open-angle glaucoma. (PubMed id 20357201)1, 4 Fan B.J....Pang C.P. (amp 2010)
    521. Tumor necrosis factor alpha promoter polymorphism in posttransplantation diabetes mellitus of renal transplant recipients. (PubMed id 21094815)1, 4 Kao C.C....Yang S.F. (Transplant. Proc. 2010)
    522. Association of TNF-alpha-238G/A and 308 G/A gene polymorphisms with pulmonary tuberculosis among patients with coal worker's pneumoconiosis. (PubMed id 20514989)1, 4 Fan H.M....Ren J.X. (Biomed. Environ. Sci. 2010)
    523. Tumor necrosis factor-alpha-308A allele may have a protective effect for chronic hepatitis B virus infection in Mongoloid populations. (PubMed id 20004605)1, 4 Zheng M.H....Chen Y.P. (Int. J. Infect. Dis. 2010)
    524. Cytokine polymorphisms and Alzheimer disease: possible associations. (PubMed id 20213229)1, 4 Ribizzi G....Megna M. (Neurol. Sci. 2010)
    525. Association of tumor necrosis factor gene polymorphisms with susceptibility to dilated cardiomyopathy in a Han Chinese population. (PubMed id 20491592)1, 4 Liang W.B....Zhang L. (DNA Cell Biol. 2010)
    526. [Relationship of tumor necrosis factor gene polymorphism and acute graft-versus-host disease after unrelated allogeneic hematopoietic stem cell transplantation]. (PubMed id 20627040)1, 4 Jin L....Huang H. (Zhonghua Nei Ke Za Zhi 2010)
    527. The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer. (PubMed id 20437058)1, 4 Hawken S.J....Little J. (Hum. Genet. 2010)
    528. Association of tumor necrosis factor alpha and IL-10 promoter polymorphisms with rheumatoid arthritis in North Indian population. (PubMed id 19779724)1, 4 Gambhir D....Naik S. (Rheumatol. Int. 2010)
    529. A 3-factor epistatic model predicts digital ulcers in Italian scleroderma patients. (PubMed id 20603050)1, 4 Beretta L....Scorza R. (Eur. J. Intern. Med. 2010)
    530. Analyses of shared genetic factors between asthma and obesity in children. (PubMed id 20816195)1, 4 MelAcn E....Lasky-Su J. (J. Allergy Clin. Immunol. 2010)
    531. Tumor necrosis factor rs361525 (-238G&gt;A) polymorphism contributes to hepatocellular carcinoma susceptibility. (PubMed id 20953524)1, 4 Guo Y.M....Shen X.Z. (Saudi Med J 2010)
    532. Is there a genetic variation association in the IL-10 and TNF alpha promoter gene with gestational diabetes mellitus? (PubMed id 20536548)1, 4 Montazeri S....Radhakrishnan A.K. (Hereditas 2010)
    533. Association between -238 but not -308 polymorphism of Tumor necrosis factor alpha (TNF-alpha)v and unexplained recurrent spontaneous abortion (URSA) in Chinese population. (PubMed id 20920206)1, 4 Liu C....Ma X. (amp 2010)
    534. Tumour necrosis factor-alpha polymorphisms and hepatocellular carcinoma: a meta-analysis. (PubMed id 20819413)1, 4 Qin H....Ma Y. (J. Int. Med. Res. 2010)
    535. [Meta-analysis of association of tumor necrosis factor alpha-308 gene promoter polymorphism with gastric cancer]. (PubMed id 20450741)1, 4 Lu P.H....Tao G.Q. (Zhonghua Yu Fang Yi Xue Za Zhi 2010)
    536. Tumour necrosis factor-I+ promoter region polymorphisms affect the course of spontaneous HBsAg clearance. (PubMed id 20825556)1, 4 Kao P.C....Chang M.H. (Liver Int. 2010)
    537. Graves' disease and gene polymorphism of TNF-I+, IL-2, IL-6, IL-12, and IFN-I^. (PubMed id 20960273)1, 4 Anvari M....Amirzargar A. (Endocrine 2010)
    538. Tumor necrosis factor-alpha gene polymorphisms are associated with severity of acute graft-versus-host disease following matched unrelated donor bone marrow transplantation in children: a Pediatric Blood and Marrow Transplant Consortium study. (PubMed id 20100586)1, 4 Goyal R.K....Atlas M. (Biol. Blood Marrow Transplant. 2010)
    539. Association of the 98T ELAM-1 polymorphism with increased bleeding after cardiac surgery. (PubMed id 20056442)1, 4 Welsby I.J....Stafford-Smith M. (J. Cardiothorac. Vasc. Anesth. 2010)
    540. IL10 GGC haplotype is positively and HLA-DQA1*05-DQB1*02 is negatively associated with radiographic progression in undifferentiated arthritis. (PubMed id 20472930)1, 4 Ursum J....van der Horst-Bruinsma I.E. (J. Rheumatol. 2010)
    541. Genetic polymorphisms in TNF genes and tuberculosis in North Indians. (PubMed id 20537163)1, 4 Sharma S....Sharma S.K. (BMC Infect. Dis. 2010)
    542. Candidate genes of cerebrovascular disease and sudden sensorineural hearing loss. (PubMed id 19833626)1, 4 Um J.Y....Kim H.M. (Clin. Appl. Thromb. Hemost. 2010)
    543. [Complex analsis of association of inflammation genes with myocardial infarction]. (PubMed id 20608170)1, 4 Sudomoina M.A....Favorova O.O. (Mol. Biol. (Mosk.) 2010)
    544. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)1, 4 He C....Hunter D.J. (Hum. Genet. 2010)
    545. Association between EGF, TGF-{beta}1, TNF-{alpha} gene polymorphisms and cancer of the pancreatic head. (PubMed id 21187523)1, 4 Wu G.Y....Keese M. (Anticancer Res. 2010)
    546. Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer. (PubMed id 20811626)1, 4 Hildebrandt M.A....Wu X. (PLoS ONE 2010)
    547. Polymorphisms of genes encoding tumor necrosis factor-alpha, interleukin-10, cluster of differentiation-14 and interleukin-1ra in critically ill patients. (PubMed id 20163933)1, 4 Surbatovic M....Magic Z. (J Crit Care 2010)
    548. Immunogenetic characteristics of patients with autoimmune gastritis. (PubMed id 20082482)1, 4 Oksanen A.M....Partanen J.A. (World J. Gastroenterol. 2010)
    549. Association between cytokine gene polymorphisms and gastric precancerous lesions: systematic review and meta-analysis. (PubMed id 20200422)1, 4 Peleteiro B....Barros H. (amp 2010)
    550. Impact of cytokine genotype on cardiovascular surrogate markers in hemodialysis patients. (PubMed id 20662694)1, 4 Yilmaz R....Turgan C. (Ren Fail 2010)
    551. Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations. (PubMed id 19934104)1, 4 Attur M....Kornman K.S. (Ann. Rheum. Dis. 2010)
    552. Labile anger during interferon alfa treatment is associated with a polymorphism in tumor necrosis factor alpha. (PubMed id 20661026)1, 4 Lotrich F.E....Pollock B.G. (Clin Neuropharmacol 2010)
    553. Association between inflammatory genetic polymorphism and acute lung injury after cardiac surgery with cardiopulmonary bypass. (PubMed id 20424554)1, 4 Wang J.F....Lu A.D. (Med. Sci. Monit. 2010)
    554. Association between polymorphism of tumor necrosis factor-alpha promoter and response to lamivudine treatment in patients with chronic hepatitis B. (PubMed id 19830555)1, 4 Park Y.K....Han K.H. (Dig. Dis. Sci. 2010)
    555. Association between TNF-alpha, TGF-beta1, IL-10, IL-6 and IFN-gamma gene polymorphisms and generalized aggressive periodontitis. (PubMed id 20370995)1, 4 Erciyas K....Orbak R. (Clin Invest Med 2010)
    556. Strong association between the -308 TNF promoter polymorphism and allergic rhinitis in Pakistani patients. (PubMed id 21313996)1, 4 Minhas K....Ahmed A. (amp 2010)
    557. C-reactive protein -717C&gt;T genetic polymorphism associates with esophagectomy-induced stress hyperglycemia. (PubMed id 20145925)1, 4 Motoyama S....Ogawa J. (World J Surg 2010)
    558. Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program. (PubMed id 20682687)1, 4 Jablonski K.A....Florez J.C. (Diabetes 2010)
    559. Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment. (PubMed id 20056178)1, 4 Segat L....Crovella S. (Vaccine 2010)
    560. Gene-gene and gene - clinical factors interaction in acute myocardial infarction: a new detailed risk chart. (PubMed id 20388088)1, 4 Licastro F....Ferrari R. (Curr. Pharm. Des. 2010)
    561. SNP/haplotype associations in cytokine and cytokine receptor genes and immunity to rubella vaccine. (PubMed id 20217072)1, 4 Dhiman N....Poland G.A. (Immunogenetics 2010)
    562. Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project. (PubMed id 20565774)1, 4 Cross D.S....McCarty C.A. (BMC Genet. 2010)
    563. Polymorphisms IL10-819 and TLR-2 are potentially associated with sepsis in Brazilian patients. (PubMed id 20835611)1, 4 Carregaro F....Leopoldino A.M. (Mem. Inst. Oswaldo Cruz 2010)
    564. Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. (PubMed id 20452482)1, 4 Romero R....Menon R. (Am. J. Obstet. Gynecol. 2010)
    565. Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer. (PubMed id 19760027)1, 4 Tsilidis K.K....Platz E.A. (amp 2009)
    566. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1, 4 Barcellos L.F....Criswell L.A. (PLoS Genet. 2009)
    567. Influence of cytokine gene variations on immunization to childhood vaccines. (PubMed id 19819209)1, 4 Yucesoy B....Luster M.I. (Vaccine 2009)
    568. Polymorphisms in the tumour necrosis factor alpha-induced protein 3 (TNFAIP3) gene are associated with chronic rhinosinusitis. (PubMed id 19344623)1, 4 Cormier C....Desrosiers M. (amp 2009)
    569. IL-10 and TNF-alpha promoter haplotypes are associated with childhood Crohn's disease location. (PubMed id 19673019)1, 4 Sanchez R....Sinnett D. (World J. Gastroenterol. 2009)
    570. Confirmation of the novel association at the BTNL2 locus with ulcerative colitis. (PubMed id 19659809)1, 4 Pathan S....Jewell D.P. (Tissue Antigens 2009)
    571. Genetic and nongenetic covariates of pain severity in patients with adenocarcinoma of the pancreas: assessing the influence of cytokine genes. (PubMed id 19692203)1, 4 Reyes-Gibby C.C....Spitz M.R. (J Pain Symptom Manage 2009)
    572. A novel exonic variant (221delT) in the LGALS13 gene encoding placental protein 13 (PP13) is associated with preterm labour in a low risk population. (PubMed id 19818512)1, 4 Gebhardt S....Hillermann R. (J. Reprod. Immunol. 2009)
    573. Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02). (PubMed id 19115949)1, 4 Limou S....Zagury J.F. (J. Infect. Dis. 2009)
    574. Influence of G308A promoter variant of tumor necrosis factor-alpha gene on insulin resistance and weight loss secondary to two hypocaloric diets: a randomized clinical trial. (PubMed id 19064125)1, 4 de Luis D.A....Conde R. (Arch. Med. Res. 2009)
    575. TNF-alpha polymorphisms in primary biliary cirrhosis: a northern and southern Italian experience. (PubMed id 19758199)1, 4 Niro G.A....Invernizzi P. (Ann. N. Y. Acad. Sci. 2009)
    576. Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk. (PubMed id 19336475)1, 4 Drenos F....Hingorani A.D. (Hum. Mol. Genet. 2009)
    577. [Selected cytokine gene polymorphisms and the risk of preterm delivery in the population of Polish women]. (PubMed id 19338208)1, 4 Kalinka J. and Bitner A. (Ginekol. Pol. 2009)
    578. TNF-alpha-308 G/A polymorphism and responsiveness to TNF-alpha blockade therapy in moderate to severe rheumatoid arthritis: a systematic review and meta-analysis. (PubMed id 19365401)1, 4 O'Rielly D.D....Rahman P. (Pharmacogenomics J. 2009)
    579. Genetic variation in immune regulation and DNA repair pathways and stomach cancer in China. (PubMed id 19661089)1, 4 Hussain S.K....Zhang Z.F. (amp 2009)
    580. Association of tumor necrosis factor alpha gene polymorphism G-308A with pseudoexfoliative glaucoma in the Pakistani population. (PubMed id 20029655)1, 4 Khan M.I....Qamar R. (Mol. Vis. 2009)
    581. Evaluation of the genetic background of standard-immunosuppressant-related toxicity in a cohort of 200 paediatric renal allograft recipients--a retrospective study. (PubMed id 19644155)1, 4 Grenda R....KaliciA8ski P. (Ann. Transplant. 2009)
    582. Tumor necrosis factor receptor superfamily, member 1B haplotypes increase or decrease the risk of inflammatory bowel diseases in a New Zealand caucasian population. (PubMed id 19421420)1, 4 Ferguson L.R....Demmers P.S. (Gastroenterol Res Pract 2009)
    583. Determination of genetic predisposition to patent ductus arteriosus in preterm infants. (PubMed id 19336370)1, 4 Dagle J.M....Murray J.C. (Pediatrics 2009)
    584. Polymorphisms in inflammatory genes and the risk of ischemic stroke and transient ischemic attack: results of a multilocus genotyping assay. (PubMed id 19028820)1, 4 Greisenegger S....Mannhalter C. (Clin. Chem. 2009)
    585. Distribution of the 22 cytokine gene polymorphisms in healthy Macedonian population. (PubMed id 19408823)1, 4 Trajkov D....Spiroski M. (Bratisl Lek Listy 2009)
    586. The major histocompatibility complex conserved extended haplotype 8.1 in AIDS-related non-Hodgkin lymphoma. (PubMed id 19654554)1, 4 Aissani B....Kaslow R.A. (J. Acquir. Immune Defic. Syndr. 2009)
    587. Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis. (PubMed id 19683555)1, 4 Fialho R.N....Bruges-Armas J. (Hum. Immunol. 2009)
    588. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (Occup Environ Med 2009)
    589. Association between cytokine gene polymorphisms and risk for upper respiratory tract infection and acute otitis media. (PubMed id 19522649)1, 4 Revai K....Chonmaitree T. (Clin. Infect. Dis. 2009)
    590. Clinical characteristics of tumors derived from colorectal cancer patients who harbor the tumor necrosis factor alpha-1031T/T and NOD2 3020insC polymorphism. (PubMed id 19679065)1, 4 KA8adny J....LubiA8ski J. (Cancer Epidemiol 2009)
    591. Ambient ozone modifies the effect of tumor necrosis factor G-308A on bronchitic symptoms among children with asthma. (PubMed id 19236316)1, 4 Lee Y.L....Gilliland F.D. (Allergy 2009)
    592. Phenotype-genotype interactions on renal function in type 2 diabetes: an analysis using structural equation modelling. (PubMed id 19479237)1, 4 Song X.Y....Chan J.C. (Diabetologia 2009)
    593. Single nucleotide polymorphisms of cytokine genes are associated with fibrosis of the intrahepatic bile duct wall in human clonorchiasis. (PubMed id 19488421)1, 4 Chung B.S....Hong S.T. (Korean J. Parasitol. 2009)
    594. Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. (PubMed id 19328558)1, 4 Yosifova A....Nakamura Y. (J Affect Disord 2009)
    595. Effects of interleukin-6 T15A single nucleotide polymorphism on baseline peritoneal solute transport rate in incident peritoneal dialysis patients. (PubMed id 19164257)1, 4 Hwang Y.H....Oh K.H. (Perit Dial Int 2009)
    596. Role of non-HLA genetic variants in end-stage renal disease. (PubMed id 19497039)1, 4 Ranganath P....Agrawal S. (Tissue Antigens 2009)
    597. [TGF-Beta1-915G/C and TNF-alpha-308G/A polymorphisms in children with asthma]. (PubMed id 19533439)1, 4 Aytekin C....Babacan E. (Tuberk Toraks 2009)
    598. The -509C/T polymorphism of transforming growth factor-beta1 is associated with increased risk for development of chronic idiopathic neutropenia. (PubMed id 19614955)1, 4 Eliopoulos D.G....Papadaki H.A. (Eur. J. Haematol. 2009)
    599. Association between polymorphisms in tumor necrosis factor (TNF) and TNF receptor genes and circulating TNF, soluble TNF receptor levels, and bone mineral density in postmenopausal Korean women. (PubMed id 19369902)1, 4 Kim H....Kim J.G. (Menopause 2009)
    600. Association of genetic profiles to Crohn's disease by linear combinations of single nucleotide polymorphisms. (PubMed id 18804983)1, 4 D'Addabbo A....Ancona N. (Artif Intell Med 2009)
    601. Association of TNFA -308 G/A and TNFRI +36 A/G gene polymorphisms with glaucoma. (PubMed id 19556827)1, 4 Razeghinejad M.R....Kamali-Sarvestani E. (Ophthalmic Res. 2009)
    602. Utility of incorporating genetic variants for the early detection of prostate cancer. (PubMed id 19223501)1, 4 Nam R.K....Narod S.A. (Clin. Cancer Res. 2009)
    603. Integrative predictive model of coronary artery calcification in atherosclerosis. (PubMed id 19948975)1, 4 McGeachie M....Ramoni M.F. (Circulation 2009)
    604. Primary lung cancer and TNF-alpha gene polymorphisms: a case-control study in a Croatian population. (PubMed id 19564826)1, 4 Flego V....RistiA8 S. (Med. Sci. Monit. 2009)
    605. Cytokine polymorphisms predict the frequency of otitis media as a complication of rhinovirus and RSV infections in children. (PubMed id 18560870)1, 4 Alper C.M....Doyle W.J. (Eur Arch Otorhinolaryngol 2009)
    606. Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994. (PubMed id 18936436)1, 4 Chang M.H....Khoury M.J. (Am. J. Epidemiol. 2009)
    607. Relevance of gamma interferon, tumor necrosis factor alpha, and interleukin-10 gene polymorphisms to susceptibility to Mediterranean spotted fever. (PubMed id 19386798)1, 4 Forte G.I....Mansueto S. (Clin. Vaccine Immunol. 2009)
    608. A common variant in DRD3 receptor is associated with autism spectrum disorder. (PubMed id 19058789)1, 4 de Krom M....van Ree J.M. (Biol. Psychiatry 2009)
    609. Infliximab dependency in children with Crohn's disease. (PubMed id 19183163)1, 4 Duricova D....Munkholm P. (amp 2009)
    610. Ankylosing spondylitis susceptibility and severity--contribution of TNF gene promoter polymorphisms at positions -238 and -308. (PubMed id 19758203)1, 4 Sousa E....Fonseca J.E. (Ann. N. Y. Acad. Sci. 2009)
    611. Influence of recipient and donor IL-10, TNFA and INFG genotypes on the incidence of acute renal allograft rejection. (PubMed id 18792803)1, 4 Azarpira N....Tarahi M.J. (Mol. Biol. Rep. 2009)
    612. Tumour necrosis factor (--308A) polymorphism in very preterm infants with bronchopulmonary dysplasia: a meta-analysis. (PubMed id 19066187)1, 4 Chauhan M....McGuire W. (Arch. Dis. Child. Fetal Neonatal Ed. 2009)
    613. Involvement of functional polymorphisms in the TNFA gene in the pathogenesis of autoimmune thyroid diseases and production of anti-thyrotropin receptor antibody. (PubMed id 19250279)1, 4 Inoue N....Iwatani Y. (Clin. Exp. Immunol. 2009)
    614. [Polymorphisms in inflammatory response genes in metastatic renal cancer]. (PubMed id 19658300)1, 4 SA!enz LA^pez P....CA^zar Olmo J.M. (Actas Urol Esp 2009)
    615. -308(G/A) TNF-alpha gene polymorphism and risk of depression late in the life. (PubMed id 19836613)1, 4 Cerri A.P....Annoni G. (Arch Gerontol Geriatr 2009)
    616. Variation in cytokine genes can contribute to severity of acetabular osteolysis and risk for revision in patients with ABG 1 total hip arthroplasty: a genetic association study. (PubMed id 19860911)1, 4 Gallo J....Petrek M. (BMC Med. Genet. 2009)
    617. Association of tumor necrosis factor-alpha-308 (G--&gt;A) polymorphism and susceptibility to brucellosis. (PubMed id 19424555)1, 4 Reza J.S....Mehrdad H. (J Microbiol Immunol Infect 2009)
    618. Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit. (PubMed id 19050632)1, 4 Henckaerts L....Van den Berghe G. (Crit. Care Med. 2009)
    619. A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients. (PubMed id 19131662)1, 4 Wang X....Cook N.R. ( a journal of cerebral circulation 2009)
    620. Genetic factors in mother-to-child transmission of HCV infection. (PubMed id 19481774)1, 4 Bevilacqua E....Amoroso A. (Virology 2009)
    621. Influence of host genetic variation on rubella-specific T cell cytokine responses following rubella vaccination. (PubMed id 19200845)1, 4 Ovsyannikova I.G....Poland G.A. (Vaccine 2009)
    622. Family-based transmission analysis of HLA genetic markers in Sardinian children with autistic spectrum disorders. (PubMed id 19167444)1, 4 Guerini F.R....Clerici M. (Hum. Immunol. 2009)
    623. TNFalpha promoter polymorphism is a risk factor for susceptibility in hepatocellular carcinoma in Korean population. (PubMed id 19545551)1, 4 Jung K.W....Hwang J.S. ( international journal of clinical chemistry 2009)
    624. [Association of tumor necrosis factor-alpha-308G/A and interleukin-6-174G/C gene polymorphisms with the susceptibility of respiratory syncytial virus bronchiolitis]. (PubMed id 19849941)1, 4 Zhang Y.L....Chen X.F. (Zhongguo Dang Dai Er Ke Za Zhi 2009)
    625. Tumour necrosis factor gene polymorphism: a predictive factor for the development of post-transplant lymphoproliferative disease. (PubMed id 19738620)1, 4 McAulay K.A....Crawford D.H. (Br. J. Cancer 2009)
    626. High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PubMed id 19453261)1, 4 Yerges L.M....Zmuda J.M. (J. Bone Miner. Res. 2009)
    627. Combining effects of polymorphism of tumor necrosis factor alpha 5'-flanking region and HLA-DRB1 on radiological progression in patients with rheumatoid arthritis. (PubMed id 19002558)1, 4 Ichikawa N....Kamatani N. (Mod Rheumatol 2009)
    628. Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach. (PubMed id 19263529)1, 4 Zee R.Y....Glynn R.J. ( international journal of clinical chemistry 2009)
    629. Candidate gene polymorphisms for ischemic stroke. (PubMed id 19729601)1, 4 Matarin M....Meschia J.F. ( a journal of cerebral circulation 2009)
    630. TNF-alpha -308 G&gt;A and -238 G&gt;A polymorphisms are not major risk factors in Caucasian patients with exfoliation glaucoma. (PubMed id 19279689)1, 4 MossbAPck G....Weger M. (Mol. Vis. 2009)
    631. Family-based analysis of tumor necrosis factor and lymphotoxin-alpha tag polymorphisms with type 1 diabetes in the population of South Croatia. (PubMed id 19167443)1, 4 Boraska V....Zemunik T. (Hum. Immunol. 2009)
    632. CTLA-4 CT60 polymorphism in thyroid and polyglandular autoimmunity. (PubMed id 19530270)1, 4 Dultz G....Kahaly G.J. (Horm. Metab. Res. 2009)
    633. Migraine and tumour necrosis factor gene polymorphism. An association study in a Sardinian sample. (PubMed id 19253056)1, 4 Asuni C....Del Zompo M. (J. Neurol. 2009)
    634. TNF-alpha-308 promotor polymorphism in patients with chronic obstructive pulmonary disease and lung cancer. (PubMed id 19469656)1, 4 Stankovic M.M....Radojkovic D.P. (Neoplasma 2009)
    635. Association of single nucleotide polymorphisms (SNPs) in TNF-LTA locus with breast cancer risk in Indian population. (PubMed id 18409070)1, 4 Kohaar I....Bharadwaj M. (Breast Cancer Res. Treat. 2009)
    636. [Association between the -1031T/C polymorphism in tumor necrosis factor-alpha gene and unstable angina]. (PubMed id 19806584)1, 4 Liu Y....Shen W.F. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2009)
    637. Tumor necrosis factor alpha and interferon gamma genes polymorphisms and serum levels in pancreatic adenocarcinoma. (PubMed id 19152246)1, 4 Talar-Wojnarowska R....Malecka-Panas E. (Neoplasma 2009)
    638. A gene-based risk score for lung cancer susceptibility in smokers and ex-smokers. (PubMed id 19789190)1, 4 Young R.P....Gamble G.D. (Postgrad Med J 2009)
    639. Relevance of IL-1 and TNF gene polymorphisms on interleukin-1beta and tumor necrosis factor-alpha gastric mucosal production. (PubMed id 19664671)1, 4 GarcA-a-GonzA!lez M.A....Lanas A. (Hum. Immunol. 2009)
    640. Association between genetic polymorphisms in cytokine genes and recurrent miscarriage--a meta-analysis. (PubMed id 19778488)1, 4 Medica I....Peterlin B. (Reprod. Biomed. Online 2009)
    641. Influence of ethnicity on pharmacogenetic variation in the Ghanaian population. (PubMed id 19546880)1, 4 Yen-Revollo J.L....Marsh S. (Pharmacogenomics J. 2009)
    642. Preliminary evidence of a genetic association between tumor necrosis factor alpha and the severity of sleep disturbance and morning fatigue. (PubMed id 19419979)1, 4 Aouizerat B.E....Miaskowski C. (Biol Res Nurs 2009)
    643. Relationships between C-reactive protein concentration and genotype in healthy volunteers. (PubMed id 19072030)1, 4 Jones J....Sandborn W.J. (Clin. Chem. Lab. Med. 2009)
    644. An assessment of a TNF polymorphic marker for the risk of HCV infection: meta-analysis and a new clinical study design. (PubMed id 19800032)1, 4 Chen Y. and Pei J. (Infect. Genet. Evol. 2009)
    645. Influence of proinflammatory cytokine gene polymorphism on childhood obesity. (PubMed id 20156727)1, 4 Popko K....Demkow U. (Eur. J. Med. Res. 2009)
    646. Common genetic variants in candidate genes and risk of familial lymphoid malignancies. (PubMed id 19573080)1, 4 Liang X.S....Goldin L.R. (Br. J. Haematol. 2009)
    647. [The specific features of TNF-alpha gene polymorphism in asthmatic patients and their relatives]. (PubMed id 19803352)1, 4 Cherkashina I.I....Liberdovskaia E.D. (Probl Tuberk Bolezn Legk 2009)
    648. A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2. (PubMed id 20085599)1, 4 Genuneit J....Moffatt M.F. (Clin. Exp. Allergy 2009)
    649. Severe obesity is associated with novel single nucleotide polymorphisms of the ESR1 and PPARgamma locus in Han Chinese. (PubMed id 19491387)1, 4 Chen H.H....Pan W.H. (Am. J. Clin. Nutr. 2009)
    650. Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies. (PubMed id 19956635)1, 4 Holmes M.V....Casas J.P. (PLoS ONE 2009)
    651. The proinflammatory cytokine TNF-alpha -308 AA genotype is associated with polyglandular autoimmunity. (PubMed id 19811436)1, 4 Dittmar M....Kahaly G.J. (Immunol. Invest. 2009)
    652. Epistasis between IL1A, IL1B, TNF, HTR2A, 5-HTTLPR and TPH2 variations does not impact alcohol dependence disorder features. (PubMed id 19742166)1, 4 Drago A....Serretti A. (Int J Environ Res Public Health 2009)
    653. Toll-like receptor signaling pathway variants and prostate cancer mortality. (PubMed id 19505919)1, 4 Stark J.R....Kraft P. (amp 2009)
    654. Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project. (PubMed id 19339270)1, 4 Canova C....Brennan P. (Cancer Res. 2009)
    655. Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PubMed id 19170196)1, 4 Shen M....Lan Q. (Environ. Mol. Mutagen. 2009)
    656. Tumor necrosis factor region polymorphisms are associated with AIDS and with cytomegalovirus retinitis. (PubMed id 19542865)1, 4 Deghaide N.H....Donadi E.A. (AIDS 2009)
    657. Role of IL-10 -1082, IFN-gamma +874, and TNF-alpha -308 genes polymorphisms in suicidal behavior. (PubMed id 19813110)1, 4 Omrani M.D....Massomi R. (Arch Suicide Res 2009)
    658. Role of TNF-alpha gene variation in idiopathic childhood ischemic stroke: a case-control study. (PubMed id 19168815)1, 4 Shi K.L....Zou L.P. (J. Child Neurol. 2009)
    659. Genetic polymorphisms modifying oxidative stress are associated with disease activity in rheumatoid arthritis patients. (PubMed id 19242068)1, 4 Bohanec Grabar P....Dolzan V. (Dis. Markers 2009)
    660. Analyses of associations with asthma in four asthma population samples from Canada and Australia. (PubMed id 19247692)1, 4 Daley D....Hudson T.J. (Hum. Genet. 2009)
    661. Tumor necrosis factor alpha and lymphotoxin alpha haplotypes in idiopathic recurrent pregnancy loss. (PubMed id 18394614)1, 4 Zammiti W....Mahjoub T. (Fertil. Steril. 2009)
    662. Tumor necrosis factor alpha and interleukin 10 promoter polymorphisms in Mexican patients with restenosis after coronary stenting. (PubMed id 19585232)1, 4 MartA-nez-RA-os M.A....Vargas-AlarcA^n G. (Biochem. Genet. 2009)
    663. Expression and genetic analysis of tumor necrosis factor-alpha (TNF-alpha) G-308A polymorphism in sporadic Alzheimer's disease in a Southern China population. (PubMed id 18992723)1, 4 Yang L....Peng Y. (Brain Res. 2009)
    664. G-308A TNF-alpha polymorphism is associated with an increased risk of hepatocellular carcinoma in the Turkish population: case-control study. (PubMed id 19683483)1, 4 Akkiz H....Doran F. (Cancer Epidemiol 2009)
    665. Impact of polymorphisms of the major histocompatibility complex class II, interleukin-10, tumor necrosis factor-alpha and cytotoxic T-lymphocyte antigen-4 genes on inhibitor development in severe hemophilia A. (PubMed id 19817985)1, 4 Pavlova A....Oldenburg J. (J. Thromb. Haemost. 2009)
    666. Cytokine genetic polymorphisms and prostate cancer aggressiveness. (PubMed id 19474090)1, 4 Zabaleta J....Ochoa A.C. (Carcinogenesis 2009)
    667. Evaluation of the effect of tumor necrosis factor-alpha gene polymorphism on the risk of peri-implantitis: a case-control study. (PubMed id 20162115)1, 4 Cury P.R....Shibli J.A. (amp 2009)
    668. Familial disease, the HLA-DRB1 shared epitope and anti-CCP antibodies influence time at appearance of substantial joint damage in rheumatoid arthritis. (PubMed id 19117726)1, 4 Rojas-Villarraga A....Anaya J.M. (J. Autoimmun. 2009)
    669. Do common genetic variants in endotoxin signaling pathway contribute to predisposition to alcoholic liver cirrhosis? (PubMed id 19278365)1, 4 PetrA!sek J....Jirsa M. (Clin. Chem. Lab. Med. 2009)
    670. Association of TNF-alpha promoter polymorphisms with aspirin-induced urticaria. (PubMed id 19250144)1, 4 Choi J.H....Park H.S. (J Clin Pharm Ther 2009)
    671. TNF-alpha gene polymorphism and TNF-alpha levels in obese Asian Indians with obstructive sleep apnea. (PubMed id 19022640)1, 4 Bhushan B....Vikram N.K. (Respir Med 2009)
    672. Cytokine gene polymorphisms in preeclampsia and eclampsia. (PubMed id 19407822)1, 4 de Lima T.H....Daher S. (Hypertens. Res. 2009)
    673. Association between a pro-inflammatory genetic profile and the risk of chronic atrophic gastritis among older adults from Germany. (PubMed id 19013788)1, 4 Gao L....Brenner H. (Eur. J. Cancer 2009)
    674. Polymorphisms of interleukin-6 and tumor necrosis factor gene promoters and cardiorespiratory function following liver transplantation: a preliminary study. (PubMed id 19376428)1, 4 Arranz Duran J....Soriano BenA-tez de Lugo A. (Transplant. Proc. 2009)
    675. Role of inflammation gene polymorphisms on pain severity in lung cancer patients. (PubMed id 19773451)1, 4 Reyes-Gibby C.C....Shete S. (amp 2009)
    676. Pro-inflammatory cytokine genes influence the clinical features of frontotemporal lobar degeneration. (PubMed id 19546559)1, 4 Rainero I....Pinessi L. (Dement Geriatr Cogn Disord 2009)
    677. Adipokine genes and prostate cancer risk. (PubMed id 19035456)1, 4 Moore S.C....Gunter M.J. (Int. J. Cancer 2009)
    678. The role of TNF genetic variants and the interaction with cigarette smoking for gastric cancer risk: a nested case-control study. (PubMed id 19615068)1, 4 Yang J.J....Park S.K. (BMC Cancer 2009)
    679. IL2-330G polymorphic allele is associated with decreased risk of Helicobacter pylori infection in adulthood. (PubMed id 19638314)1, 4 Queiroz D.M....Bittencourt P.F. (Microbes Infect. 2009)
    680. Tumour necrosis factor alpha gene (TNF-alpha) -376 polymorphism in Hungarian patients with primary progressive multiple sclerosis. (PubMed id 19201038)1, 4 Losonczi E....VAccsei L. (J. Neuroimmunol. 2009)
    681. The value of HLA-DRB1 shared epitope, -308 tumor necrosis factor-alpha gene promoter polymorphism, rheumatoid factor, anti-citrullinated peptide antibodies, and early erosions for predicting radiological outcome in recent-onset rheumatoid arthritis. (PubMed id 19411391)1, 4 Reneses S....GarcA-a A. (J. Rheumatol. 2009)
    682. Perioperative genomic profiles using structure-specific oligonucleotide probes. (PubMed id 19474452)1, 4 Hogan K.J....Domanico M.J. (amp 2009)
    683. Interleukin-10 is associated with resistance to febrile seizures: genetic association and experimental animal studies. (PubMed id 19055487)1, 4 Ishizaki Y....Hara T. (Epilepsia 2009)
    684. Inflammatory cytokine gene polymorphisms and spontaneous preterm birth. (PubMed id 19375805)1, 4 Moura E....Daher S. (J. Reprod. Immunol. 2009)
    685. Synopsis and synthesis of candidate-gene association studies in chronic lymphocytic leukemia: the CUMAGAS-CLL information system. (PubMed id 19700502)1, 4 Zintzaras E. and Kitsios G.D. (Am. J. Epidemiol. 2009)
    686. Association of tumour necrosis factor-alpha gene (T-1031C, C-863A, and C-857T) polymorphisms with bladder cancer susceptibility and outcome after bacille Calmette-GuAcrin immunotherapy. (PubMed id 19338536)1, 4 Ahirwar D.K....Mittal R.D. (BJU Int. 2009)
    687. A candidate gene association study of 77 polymorphisms in migraine. (PubMed id 19559392)1, 4 SchA1rks M....Zee R.Y. (J Pain 2009)
    688. HLA-E gene polymorphism associated with susceptibility to Kawasaki disease and formation of coronary artery aneurysms. (PubMed id 19180512)1, 4 Lin Y.J....Tsai F.J. (Arthritis Rheum. 2009)
    689. Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants. (PubMed id 19527514)1, 4 Menon R....Thorsen P. (amp 2009)
    690. Retinopathy and nephropathy in type 1 diabetic patients--association with polymorphysms of vitamin D-receptor, TNF, Neuro-D and IL-1 receptor 1 genes. (PubMed id 20120526)1, 4 BuA8an K....Znaor L. (Coll Antropol 2009)
    691. Association of tumor necrosis factor alpha, interferon gamma and interleukin 10 gene polymorphisms with peripheral neuropathy in South Indian patients with type 2 diabetes. (PubMed id 19608431)1, 4 Kolla V.K....Akka J. (Cytokine 2009)
    692. Polymorphisms at cytokine genes may determine the effect of vitamin E on cytokine production in the elderly. (PubMed id 19710156)1, 4 Belisle S.E....Meydani S.N. (J. Nutr. 2009)
    693. [Transforming growth factor beta and tumor necrosis factor gene polymorphism and coal worker's pneumoconiosis]. (PubMed id 19493496)1, 4 Yu C....Qi F. (Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2009)
    694. TNF, LTA, HSPA1L and HLA-DR gene polymorphisms in HIV-positive patients with hypersensitivity to cotrimoxazole. (PubMed id 19374512)1, 4 Alfirevic A....Pirmohamed M. (Pharmacogenomics 2009)
    695. Association of SLC11A1 with tuberculosis and interactions with NOS2A and TLR2 in African-Americans and Caucasians. (PubMed id 19723394)1, 4 Velez D.R....Scott W.K. (Int. J. Tuberc. Lung Dis. 2009)
    696. [The relationship among IL-10, TNF gene polymorphisms, Helicobacter pylori infection and gastroduodenal diseases in Hubei Han ethnic]. (PubMed id 19957794)1, 4 Xiao H....Xia B. (Zhonghua Nei Ke Za Zhi 2009)
    697. Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1. (PubMed id 19143814)1, 4 Valdes A.M. and Thomson G. (amp 2009)
    698. Extensive genetic polymorphism in the haplotype STR-TNF and HLA class I with the onset and evolution of psoriasis vulgaris. (PubMed id 19574026)1, 4 Biral A.C....Kraemer M.H. (J. Dermatol. Sci. 2009)
    699. Lack of association between TNF 238 G/A polymorphism and type 2 diabetes: a meta-analysis. (PubMed id 19367363)1, 4 Feng R....Sun C. (Acta Diabetol 2009)
    700. The combinations of TNFalpha-308 and IL-6 -174 or IL-10 -1082 genes polymorphisms suggest an association with susceptibility to sporadic late-onset Alzheimer's disease. (PubMed id 19744138)1, 4 Vural P....Uysal M. (Acta Neurol. Scand. 2009)
    701. Incidence of adverse cutaneous drug reactions in a Mexican sample: an exploratory study on their association to tumour necrosis factor alpha TNF2 allele. (PubMed id 19309429)1, 4 Charli-Joseph Y....Orozco-Topete R. (J Eur Acad Dermatol Venereol 2009)
    702. Cluster analysis of risk factor genetic polymorphisms in Alzheimer's disease. (PubMed id 18307033)1, 4 Randall C.N....Poduslo S.E. (Neurochem. Res. 2009)
    703. Association of 22 cytokine gene polymorphisms with tuberculosis in Macedonians. (PubMed id 20349753)1, 4 Trajkov D....Spiroski M. (Indian J Tuberc 2009)
    704. Influence of TNF and IL10 gene polymorphisms in the immunopathogenesis of leprosy in the south of Brazil. (PubMed id 19058987)1, 4 Franceschi D.S....Visentainer J.E. (Int. J. Infect. Dis. 2009)
    705. Autoimmune pancreatitis associated with high prevalence of gastric ulcer independent of Helicobacter pylori infection status. (PubMed id 19276869)1, 4 Chang M.C....Wong J.M. (Pancreas 2009)
    706. PTEN identified as important risk factor of chronic obstructive pulmonary disease. (PubMed id 19625176)1, 4 Hosgood H.D....Lan Q. (Respir Med 2009)
    707. An association study of 13 SNPs from seven candidate genes with pediatric asthma and a preliminary study for genetic testing by multiple variants in Taiwanese population. (PubMed id 18931892)1, 4 Wang J.Y....Wu L.S. (J. Clin. Immunol. 2009)
    708. Allelic variants of CD40 and CD40L genes interact to promote antibiotic-induced cutaneous allergic reactions. (PubMed id 19735272)1, 4 Kim S.H....Park H.W. (Clin. Exp. Allergy 2009)
    709. Association of TNFA (-308G&gt;A) and IL-10 (-819C&gt;T) promoter polymorphisms with risk of cervical cancer. (PubMed id 19823053)1, 4 Singh H....Mittal B. (Int. J. Gynecol. Cancer 2009)
    710. Cancer cachexia is associated with the IL10 -1082 gene promoter polymorphism in patients with gastroesophageal malignancy. (PubMed id 19244371)1, 4 Deans D.A....Fearon K.C. (Am. J. Clin. Nutr. 2009)
    711. Genetic polymorphisms in the cytokine genes and risk of hepatocellular carcinoma in low-risk non-Asians of USA. (PubMed id 19126646)1, 4 Ognjanovic S....Yu M.C. (Carcinogenesis 2009)
    712. Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone. (PubMed id 18996102)1, 4 RuaA+o G....Hanks S. ( international journal of clinical chemistry 2009)
    713. Association between tumor necrosis factor alpha 308G/A polymorphism and increased proinflammatory cytokine release after cardiac surgery with cardiopulmonary bypass in the Korean population. (PubMed id 19467887)1, 4 Yoon S.Z....Yoon S.M. (J. Cardiothorac. Vasc. Anesth. 2009)
    714. TNF 308 G/A polymorphism and type 1 diabetes: a meta-analysis. (PubMed id 19477545)1, 4 Feng R.N....Sun C.H. (Diabetes Res. Clin. Pract. 2009)
    715. Synergistic effect of HLA class II loci and cytokine gene polymorphisms on the risk of gastric cancer in Japanese patients with Helicobacter pylori infection. (PubMed id 19544559)1, 4 Ando T....Yoshikawa T. (Int. J. Cancer 2009)
    716. [Influence of three point mutations in TNF-alpha promoter gene in clinical manifestations and complications of stomach and duodenal ulcer]. (PubMed id 19548417)1, 4 Polonikov A.V....Bulgakova I.V. (amp 2009)
    717. Cytokine and cytokine receptor single-nucleotide polymorphisms predict risk for non-small cell lung cancer among women. (PubMed id 19505916)1, 4 Van Dyke A.L....Schwartz A.G. (amp 2009)
    718. CRP genetic polymorphism is associated with lymph node metastasis in thoracic esophageal squamous cell cancer. (PubMed id 19495883)1, 4 Motoyama S....Ogawa J. (Ann. Surg. Oncol. 2009)
    719. Genetic factors associated with rheumatoid arthritis and systemic vasculitis: Evaluation of a panel of polymorphisms. (PubMed id 20037209)1, 4 Menegatti E....Roccatello D. (Dis. Markers 2009)
    720. Tumor necrosis factor and lymphotoxin-alpha polymorphisms and severe malaria in African populations. (PubMed id 19281305)1, 4 Clark T.G....Kwiatkowski D.P. (J. Infect. Dis. 2009)
    721. Clinical application of cytokine-related gene polymorphism analysis using a newly developed DNA chip in critically ill patients. (PubMed id 19527699)1, 4 Otani S....Hirasawa H. (Clin. Biochem. 2009)
    722. A candidate gene approach to genetic prognostic factors of IgA nephropathy--a result of Polymorphism REsearch to DIstinguish genetic factors Contributing To progression of IgA Nephropathy (PREDICT-IgAN). (PubMed id 19420105)1, 4 Yamamoto R....Rakugi H. (Nephrol. Dial. Transplant. 2009)
    723. [The influence of selected cytokine gene polymorphisms on the occurrence of acute and chronic rejection and on kidney graft survival]. (PubMed id 20097948)1, 4 Kocierz M....Wiecek A. (Postepy Hig Med Dosw (Online) 2009)
    724. Association of cytokine and chemokine gene polymorphisms with severe acute respiratory syndrome. (PubMed id 19258635)1, 4 Lau Y.L. and Peiris J.S. (Hong Kong Med J 2009)
    725. Association study between candidate genes and obesity-related phenotypes using a sample of lumberjacks. (PubMed id 19367093)1, 4 Chamberland A....Laprise C. (Public Health Genomics 2009)
    726. Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. (PubMed id 19258923)1, 4 Siezen C.L....Janssen R. (Pediatr. Infect. Dis. J. 2009)
    727. Evidence of epistasis between interleukin 1 and selenoprotein-S with susceptibility to rheumatoid arthritis. (PubMed id 18728048)1, 4 Marinou I....Wilson A.G. (Ann. Rheum. Dis. 2009)
    728. Association between TNFA-308 G/A polymorphism and sensitization to para-phenylenediamine: a case-control study. (PubMed id 18384449)1, 4 BlAPmeke B....Coenraads P.J. (Allergy 2009)
    729. Interferon-gamma 874A&gt;T genetic polymorphism is associated with infectious complications following surgery in patients with thoracic esophageal cancer. (PubMed id 19733878)1, 4 Motoyama S....Ogawa J. (Surgery 2009)
    730. Immune response and gene polymorphism profiles in Crohn's disease and ulcerative colitis. (PubMed id 18942754)1, 4 Queiroz D.M....Castro L.P. (Inflamm. Bowel Dis. 2009)
    731. Variation in the TLR4 gene influences the risk of organ failure and shock posttrauma: a cohort study. (PubMed id 19131814)1, 4 Shalhub S....O'Keefe G.E. (J Trauma 2009)
    732. Fatty acids, IL6, and TNFalpha polymorphisms: an example of nutrigenetics in Crohn's disease. (PubMed id 19550417)1, 4 Guerreiro C.S....Cravo M. (Am. J. Gastroenterol. 2009)
    733. Association of genetic variants with chronic kidney disease in individuals with different lipid profiles. (PubMed id 19578796)1, 4 Yoshida T....Yamada Y. (Int. J. Mol. Med. 2009)
    734. Common variants in immune and DNA repair genes and risk for human papillomavirus persistence and progression to cervical cancer. (PubMed id 19012493)1, 4 Wang S.S....Hildesheim A. (J. Infect. Dis. 2009)
    735. Systematic review by meta-analyses on the possible role of TNF-alpha polymorphisms in association with Alzheimer's disease. (PubMed id 19445962)1, 4 Di Bona D....Caruso C. (Brain Res Rev 2009)
    736. Distribution of cytokine gene polymorphisms in the general Lebanese population: the first report. (PubMed id 19594368)1, 4 Mahfouz R.A....Bazarbachi A. (Genet Test Mol Biomarkers 2009)
    737. Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. (PubMed id 19019335)1, 4 Velez D.R....Menon R. (Am. J. Obstet. Gynecol. 2009)
    738. The genomic basis of cerebral palsy: a HuGE systematic literature review. (PubMed id 19238444)1, 4 O'Callaghan M.E....Dekker G. (Hum. Genet. 2009)
    739. Inverse association between a pro-inflammatory genetic profile and Helicobacter pylori seropositivity among patients with chronic atrophic gastritis: enhanced elimination of the infection during disease progression? (PubMed id 19427781)1, 4 Gao L....Brenner H. (Eur. J. Cancer 2009)
    740. Proinflammatory cytokine gene polymorphisms among Iranian patients with asthma. (PubMed id 18763028)1, 4 Mahdaviani S.A....Movahedi M. (J. Clin. Immunol. 2009)
    741. Genetic polymorphisms of the lymphotoxin alpha gene are associated with increased risk for lethal infections during induction therapy for childhood acute leukemia: a case-control study. (PubMed id 19353239)1, 4 Kidas E....Grigull L. (Int. J. Hematol. 2009)
    742. Polymorphisms in tumor necrosis factor-A gene and prostate cancer risk in North Indian cohort. (PubMed id 19846139)1, 4 Kesarwani P....Mittal R.D. (J. Urol. 2009)
    743. HLA-association of serum levels of natural antibodies. (PubMed id 19167759)1, 4 Pozsonyi E....FA1st G. (Mol. Immunol. 2009)
    744. Cytokine polymorphisms and severity of tubal damage in women with Chlamydia-associated infertility. (PubMed id 19358670)1, 4 Ohman H....Surcel H.M. (J. Infect. Dis. 2009)
    745. Tumor necrosis factor gene variation and the risk of mortality after burn injury: a cohort study. (PubMed id 19060757)1, 4 Shalhub S....O'keefe G.E. (amp 2009)
    746. Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic syndrome. (PubMed id 19056482)1, 4 Yoshida T....Yamada Y. (Genomics 2009)
    747. [Genetic predisposition to multiple sclerosis as a polygenic autoimmune disease]. (PubMed id 19894308)1, 4 Favorova O.O....Ochs M.F. (Zh Nevrol Psikhiatr Im S S Korsakova 2009)
    748. Gene polymorphisms of TNF-alpha-308 (G/A), IL-10(-1082) (G/A), IL-6(-174) (G/C) and IL-1Ra (VNTR) in Egyptian cases with type 1 diabetes mellitus. (PubMed id 19127455)1, 4 Settin A....Kazamel A. (Autoimmunity 2009)
    749. Single nucleotide polymorphisms in obesity-related genes and all-cause and cause-specific mortality: a prospective cohort study. (PubMed id 19818126)1, 4 Gallicchio L....Helzlsouer K.J. (BMC Med. Genet. 2009)
    750. Association of candidate gene polymorphisms with chronic kidney disease in Japanese individuals with hypertension. (PubMed id 19282863)1, 4 Yoshida T....Yamada Y. (Hypertens. Res. 2009)
    751. Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium. (PubMed id 19423537)1, 4 Gaudet M.M....Garcia-Closas M. (amp 2009)
    752. Association of polymorphisms in the tumor necrosis factor-alpha and interleukin-10 genes with oral lichen planus: a study in a chinese cohort with Han ethnicity. (PubMed id 19450147)1, 4 Bai J....Chen Q. (amp 2009)
    753. Contribution of TNF-308A and CCL2-2518A to carotid intima-media thickness in obese mexican children and adolescents. (PubMed id 18996288)1, 4 GonzA!lez-EnrA-quez G.V....Leal-CortAcs C.A. (Arch. Med. Res. 2008)
    754. Gene expression polymorphisms of interleukins-1 beta, -4, -6, -8, -10, and tumor necrosis factors-alpha, -beta: regression analysis of their effect upon oral squamous cell carcinoma. (PubMed id 18273643)1, 4 Vairaktaris E....Patsouris E. (J. Cancer Res. Clin. Oncol. 2008)
    755. IL-1, IL-1R and TNFalpha gene polymorphisms in Iranian patients with multiple sclerosis. (PubMed id 18322311)1, 4 Sarial S....Lotfi J. (Iran J Allergy Asthma Immunol 2008)
    756. Tumor necrosis factor alpha-308 gene polymorphism in patients with anorexia nervosa. (PubMed id 18773665)1, 4 Kanbur N....Tezcan I. (Turk. J. Pediatr. 2008)
    757. Prevalence and risk factors of atrophic gastritis and intestinal metaplasia in a Korean population without significant gastroduodenal disease. (PubMed id 18665932)1, 4 Kim N....Song I.S. (Helicobacter 2008)
    758. Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China. (PubMed id 18676870)1, 4 Hsing A.W....Chanock S.J. (Cancer Res. 2008)
    759. The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer. (PubMed id 19094228)1, 4 Tapper W....Eccles D. (Breast Cancer Res. 2008)
    760. TNF-alpha and IL-10 gene polymorphisms versus cardioimmunological responses in sudden infant death. (PubMed id 18633768)1, 4 Perskvist N....Palm U. (Fetal Pediatr Pathol 2008)
    761. Polymorphisms in the tumor necrosis factor/lipopolysaccharides pathway in Crohn disease in the Jewish Ashkenazi population. (PubMed id 18493210)1, 4 Silbermintz A....Silver J. (J. Pediatr. Gastroenterol. Nutr. 2008)
    762. Association of specific haplotype of TNFalpha with Helicobacter pylori-mediated duodenal ulcer in eastern Indian population. (PubMed id 19147919)1, 4 Chakravorty M....Roychoudhury S. (J. Genet. 2008)
    763. Interleukin-10 (-819 C/T) and tumor necrosis factor-alpha (-308 G/A) gene variants influence gastritis and lymphoid follicle development. (PubMed id 17717744)1, 4 Achyut B.R....Mittal B. (Dig. Dis. Sci. 2008)
    764. Systemic inflammatory response predicts prognosis in patients with advanced-stage colorectal cancer. (PubMed id 18794066)1, 4 Sharma R....Clarke S.J. (Clin Colorectal Cancer 2008)
    765. Common studied polymorphisms do not affect plasma cytokine levels upon endotoxin exposure in humans. (PubMed id 18307517)1, 4 Taudorf S....Bruunsgaard H. (Clin. Exp. Immunol. 2008)
    766. Association between tumor necrosis factor (TNF)-alpha G-308A gene polymorphism and preeclampsia complicated by severe fetal growth restriction. (PubMed id 18396154)1, 4 Molvarec A....RigA^ J. ( international journal of clinical chemistry 2008)
    767. Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome: The Finnish Diabetes Prevention Study. (PubMed id 18249219)1, 4 KilpelAoinen T.O....Uusitupa M. (Metab. Clin. Exp. 2008)
    768. Frequency of distribution of inflammatory cytokines IL-1, IL-6 and TNF-alpha gene polymorphism in patients with obstructive sleep apnea. (PubMed id 19218687)1, 4 Popko K....Demkow U. (J. Physiol. Pharmacol. 2008)
    769. Lack of association between thrombosis-associated and cytokine candidate gene polymorphisms and acute rejection or vascular complications after kidney transplantation. (PubMed id 17704111)1, 4 Alakulppi N.S....Laine J.T. (Nephrol. Dial. Transplant. 2008)
    770. Persistent association of nailfold capillaroscopy changes and skin involvement over thirty-six months with duration of untreated disease in patients with juvenile dermatomyositis. (PubMed id 18240225)1, 4 Christen-Zaech S....Pachman L.M. (Arthritis Rheum. 2008)
    771. Tumor necrosis factor alpha-308 and -238 polymorphisms in rheumatoid arthritis. Association with messenger RNA expression and sTNF-alpha. (PubMed id 18797411)1, 4 OregA^n-Romero E....MuA+oz-Valle J.F. (J. Investig. Med. 2008)
    772. The influence of tumor necrosis factor-alpha -308 G/A and IL-6 -174 G/C on pain and analgesia response in lung cancer patients receiving supportive care. (PubMed id 18990769)1, 4 Reyes-Gibby C.C....Bruera E. (amp 2008)
    773. Cytokine polymorphisms in women with recurrent pregnancy loss: meta-analysis. (PubMed id 18366487)1, 4 Bombell S. and McGuire W. (amp 2008)
    774. The simultaneous presence of IL-1B and TNFA two-positions risk haplotypes enhances the susceptibility for celiac disease. (PubMed id 18346907)1, 4 CherA+avsky A.C....Anaya J.M. (Cytokine 2008)
    775. A variant of position -308 of the Tumour necrosis factor alpha gene promoter and the risk of coronary heart disease. (PubMed id 17581788)1, 4 Elahi M.M....Mastana S.S. (amp 2008)
    776. [Association between tumor necrosis factor alpha gene polymorphism and colorectal cancer]. (PubMed id 19031138)1, 4 Wu G.Y....Sturm J.W. (Zhonghua Wei Chang Wai Ke Za Zhi 2008)
    777. Effect of the polymorphism of tumor necrosis factor-alpha-308 G/A gene promoter on the susceptibility to ulcerative colitis: a meta-analysis. (PubMed id 18827481)1, 4 Lu Z....Lin L. (Digestion 2008)
    778. Anti- and proinflammatory cytokine gene polymorphism and genetic predisposition: association with smoking, tumor stage and grade, and bacillus Calmette-GuAcrin immunotherapy in bladder cancer. (PubMed id 18558283)1, 4 Ahirwar D....Mittal R.D. (Cancer Genet. Cytogenet. 2008)
    779. Inflammatory cytokine gene variants in coronary artery disease patients in Greece. (PubMed id 19005292)1, 4 Manginas A....Cokkinos D.V. (Coron. Artery Dis. 2008)
    780. [Screening and analysis of multi-alleles in generalized aggressive periodontitis]. (PubMed id 19031816)1, 4 Wang H.Y. and Pan Y.P. (Zhonghua Kou Qiang Yi Xue Za Zhi 2008)
    781. Polymorphisms of tumor necrosis factor-alpha are associated with increased susceptibility to gastric cancer: a meta-analysis. (PubMed id 18350251)1, 4 Zhang J....Mao Y. (J. Hum. Genet. 2008)
    782. Single nucleotide polymorphisms in inflammation-related genes and mortality in a community-based cohort in Washington County, Maryland. (PubMed id 18263601)1, 4 Gallicchio L....Helzlsouer K.J. (Am. J. Epidemiol. 2008)
    783. Association of tumor necrosis factor-{alpha} gene polymorphisms with advanced stage endometriosis. (PubMed id 18272527)1, 4 Lee G.H....Moon S.Y. (Hum. Reprod. 2008)
    784. IL6 (-174) and TNFA (-308) promoter polymorphisms are associated with systemic creatine kinase response to eccentric exercise. (PubMed id 18758806)1, 4 Yamin C....Amir R.E. (Eur. J. Appl. Physiol. 2008)
    785. Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era. (PubMed id 18633131)1, 4 Habermann T.M....Cerhan J.R. (Blood 2008)
    786. Association of inflammatory cytokine gene polymorphisms with platelet recovery in idiopathic thrombocytopenic purpura patients after the eradication of Helicobacter pylori. (PubMed id 18354254)1, 4 Suzuki T....Mine T. (Digestion 2008)
    787. Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. (PubMed id 19064572)1, 4 Palmieri R.T.... . (amp 2008)
    788. A pilot case-control association study of cytokine polymorphisms in Brazilian women presenting with HPV-related cervical lesions. (PubMed id 18502564)1, 4 Fernandes A.P....Donadi E.A. (Eur. J. Obstet. Gynecol. Reprod. Biol. 2008)
    789. Analysis of TNF polymorphisms in Turkish systemic sclerosis patients with interstitial lung involvement. (PubMed id 18797991)1, 4 Ates O....Topal-Sarikaya A. (Biochem. Genet. 2008)
    790. TNF-alpha gene polymorphism and fetal Doppler velocimetry in intrauterine growth restriction. (PubMed id 18766139)1, 4 Seremak-Mrozikiewicz A....Mrozikiewicz P.M. (Neuro Endocrinol. Lett. 2008)
    791. Independent association of tumor necrosis factor polymorphism with type 1 diabetes susceptibility. (PubMed id 19120272)1, 4 Shin H.D....Park Y. (Ann. N. Y. Acad. Sci. 2008)
    792. SNP combinations in chromosome-wide genes are associated with bone mineral density in Taiwanese women. (PubMed id 18551993)1, 4 Lin G.T....Chang H.W. (Chin J Physiol 2008)
    793. Association of TNF promoter polymorphisms with type 1 diabetes in the South Croatian population. (PubMed id 18949133)1, 4 Boraska V....Zemunik T. (Biol. Res. 2008)
    794. Tumor necrosis factor alpha extended haplotypes and risk of gastric carcinoma. (PubMed id 18768512)1, 4 Canedo P....Machado J.C. (amp 2008)
    795. TNF gene polymorphisms in Graves' disease: TNF-308 A/G meta-analysis. (PubMed id 18989801)1, 4 Kammoun-Krichen M....Ayadi H. (Ann. Hum. Biol. 2008)
    796. Modulation of type 1 diabetes susceptibility by tumor necrosis factor alpha -308 G/A and lymphotoxin alpha +249 A/G haplotypes and lack of linkage disequilibrium with predisposing DQB1-DRB1 haplotypes in Bahraini patients. (PubMed id 17989340)1, 4 Stayoussef M....Almawi W.Y. (Clin. Vaccine Immunol. 2008)
    797. Association between cytokine gene polymorphisms and outcomes in renal transplantation: a meta-analysis of individual patient data. (PubMed id 18408074)1, 4 Thakkinstian A....Attia J. (Nephrol. Dial. Transplant. 2008)
    798. Associations between cytokine/cytokine receptor single nucleotide polymorphisms and humoral immunity to measles, mumps and rubella in a Somali population. (PubMed id 18715339)1, 4 Dhiman N....Poland G.A. (Tissue Antigens 2008)
    799. Association of donor inflammation- and apoptosis-related genotypes and delayed allograft function after kidney transplantation. (PubMed id 18640487)1, 4 Israni A.K....Feldman H.I. (Am. J. Kidney Dis. 2008)
    800. Assessment of laboratory measurements and -308 TNFalpha gene promoter polymorphisms in normal bone mineral density. (PubMed id 17684700)1, 4 Canhao H....Queiroz M.V. (Clin. Rheumatol. 2008)
    801. Association of tumor necrosis factor-alpha and interleukin-10 gene polymorphisms in Iranian patients with pre-eclampsia. (PubMed id 18705845)1, 4 Mirahmadian M....Amirzargar A.A. (Am. J. Reprod. Immunol. 2008)
    802. Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants. (PubMed id 18818748)1, 4 Velez D.R....Menon R. (PLoS ONE 2008)
    803. [Tumor necrosis factor gene polymorphisms in breast cancer patients]. (PubMed id 18846826)1, 4 Ostashkin A.S....Mazurenko N.N. (Genetika 2008)
    804. Tumor necrosis factor-alpha -308 polymorphism in infertile men with altered sperm production or motility. (PubMed id 18689851)1, 4 Tronchon V....Benahmed M. (Hum. Reprod. 2008)
    805. Genetic variants associated with insulin resistance and metabolic syndrome in young Asian Indians with myocardial infarction. (PubMed id 18710329)1, 4 Ranjith N....Rom L. (Metab Syndr Relat Disord 2008)
    806. No association found between the promoter variants of TNF-alpha and diabetic retinopathy in Chinese patients with type 2 diabetes. (PubMed id 18398712)1, 4 Wang N....Xu X. (Curr. Eye Res. 2008)
    807. Interactions between glutathione S-transferase P1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease. (PubMed id 18709160)1, 4 MelAcn E....Pershagen G. (Environ. Health Perspect. 2008)
    808. Effect of the TNFalpha-308 G/A polymorphism on the changes produced by atorvastatin in bone mineral density in patients with acute coronary syndrome. (PubMed id 18997459)1, 4 PAcrez-CastrillA^n J.L....Duenas-Laita A. (amp 2008)
    809. Haplotype-specific pattern of association of human major histocompatibility complex with non-Hodgkin's lymphoma outcome. (PubMed id 17971052)1, 4 Nowak J....Warzocha K. (Tissue Antigens 2008)
    810. The association between cytokine gene polymorphisms and kidney allograft survival. (PubMed id 18566561)1, 4 Pawlik A....Dabrowska-Zamojcin E. (Ann. Transplant. 2008)
    811. Association of TNF-alpha -308 polymorphism with the outcome of hepatitis B virus infection in Turkey. (PubMed id 17974504)1, 4 Basturk B....Oral B. (Infect. Genet. Evol. 2008)
    812. Association of alleles carried at TNFA -850 and BAT1 -22 with Alzheimer's disease. (PubMed id 18715507)1, 4 Gnjec A....Martins R.N. (J Neuroinflammation 2008)
    813. Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus. (PubMed id 18174230)1, 4 Miyagawa H....Horiuchi T. (Rheumatology (Oxford) 2008)
    814. Cytokine gene polymorphisms as risk and severity factors for juvenile dermatomyositis. (PubMed id 19035492)1, 4 Mamyrova G....Rider L.G. (Arthritis Rheum. 2008)
    815. Gender differences in genetic risk profiles for cardiovascular disease. (PubMed id 18974842)1, 4 Silander K....Peltonen L. (PLoS ONE 2008)
    816. DNA polymorphisms and response to treatment in patients with chronic hepatitis C: results from the HALT-C trial. (PubMed id 18619701)1, 4 Morgan T.R....O'Brien T.R. (J. Hepatol. 2008)
    817. Role of polymorphisms of the inflammatory response genes and DC-SIGNR in genetic susceptibility to SARS and other infections. (PubMed id 18708672)1, 4 Khoo U.S....Peiris J.S. (Hong Kong Med J 2008)
    818. Polymorphism in the tumor necrosis factor-alpha gene promoter is associated with severity of rheumatoid arthritis in the Czech population. (PubMed id 17562093)1, 4 Nemec P....Gatterova J. (Clin. Rheumatol. 2008)
    819. Identification of novel single nucleotide polymorphisms in inflammatory genes as risk factors associated with trachomatous trichiasis. (PubMed id 18974840)1, 4 Atik B....Dean D. (PLoS ONE 2008)
    820. Association study of the interleukin-1 gene complex and tumor necrosis factor alpha gene with suicide attempts. (PubMed id 18496214)1, 4 SA!iz P.A....Bobes J. (Psychiatr. Genet. 2008)
    821. Tumour necrosis factor alpha -308G/A gene polymorphism: lack of association with knee osteoarthritis in a Turkish population. (PubMed id 19032806)1, 4 Sezgin M....Erdal M.E. (Clin. Exp. Rheumatol. 2008)
    822. Influence of cytokine and intercellular adhesion molecule-1 gene polymorphisms on acute rejection in pediatric renal transplantation. (PubMed id 18627514)1, 4 Mendoza-Carrera F....Leal C. (Pediatr Transplant 2008)
    823. Gene polymorphisms of tumor necrosis factor alpha-308 and interleukin-10-1082 among asthmatic Egyptian children. (PubMed id 18534084)1, 4 Zedan M....Osman E. (Allergy Asthma Proc 2008)
    824. Alleles -308A and -1031C in the TNF-alpha gene promoter do not increase the risk but associated with circulating levels of TNF-alpha and clinical features of vivax malaria in Indian patients. (PubMed id 17996942)1, 4 Sohail M....Adak T. (Mol. Immunol. 2008)
    825. T-251A polymorphism of IL-8 relating to the development of histological gastritis and G-308A polymorphism of TNF-alpha relating to the development of macroscopic erosion. (PubMed id 18301299)1, 4 Szoke D....Tulassay Z. (amp 2008)
    826. Cytokine genotype suggests a role for inflammation in nucleoside analog-associated sensory neuropathy (NRTI-SN) and predicts an individual's NRTI-SN risk. (PubMed id 18240960)1, 4 Cherry C.L....Price P. (AIDS Res. Hum. Retroviruses 2008)
    827. Analysis of IL-10, IL-4 and TNF-alpha polymorphisms in drug-induced liver injury (DILI) and its outcome. (PubMed id 18485518)1, 4 Pachkoria K....Andrade R.J. (J. Hepatol. 2008)
    828. Interactions of cytokine gene polymorphisms in prostate cancer risk. (PubMed id 18174250)1, 4 Zabaleta J....Ochoa A.C. (Carcinogenesis 2008)
    829. Cytokine genotypes in acute pancreatitis: association with etiology, severity, and cytokine levels in blood. (PubMed id 18815552)1, 4 de-Madaria E....PAcrez-Mateo M. (Pancreas 2008)
    830. Genetics of humoral and cytokine activation in heart failure and its importance for risk stratification of patients. (PubMed id 18442814)1, 4 SpinarovA! L....VA-tovec J. (Exp. Mol. Pathol. 2008)
    831. New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background. (PubMed id 18513389)1, 4 Penco S....Grossi E. (BMC Bioinformatics 2008)
    832. The TNFalpha gene relates to clinical phenotype in alpha-1-antitrypsin deficiency. (PubMed id 18620570)1, 4 Wood A.M....Stockley R.A. (Respir. Res. 2008)
    833. Association of four DNA polymorphisms with acute rejection after kidney transplantation. (PubMed id 18444945)1, 4 GrinyA^ J....Essioux L. (Transpl. Int. 2008)
    834. Rapid genotyping of tumor necrosis factor alpha with fluorogenic hybridization probes on the LightCycler. (PubMed id 18815866)1, 4 Hayashi N....Baba H. (Clin. Exp. Med. 2008)
    835. Lack of association between TNF-alpha polymorphisms and Alzheimer's disease in an Italian cohort. (PubMed id 18834925)1, 4 Tedde A....Sorbi S. (Neurosci. Lett. 2008)
    836. Genetic regulation of amniotic fluid TNF-alpha and soluble TNF receptor concentrations affected by race and preterm birth. (PubMed id 18807256)1, 4 Menon R....Williams S.M. (Hum. Genet. 2008)
    837. Frequency of S and Z alleles for alpha-1-antitrypsin and tumor necrosis factor alpha -308 promoter polymorphism in northeastern Mexico. (PubMed id 18534053)1, 4 SA!nchez-DomA-nguez C.N....Ortiz-LA^pez R. (Allergy Asthma Proc 2008)
    838. The relationship between ApoE, TNFA, IL1a, IL1b and IL12b genes and HIV-1-associated dementia. (PubMed id 18631256)1, 4 Pemberton L.A....Brew B.J. (HIV Med. 2008)
    839. Association of TGF-beta1 codon 25 (G915C) polymorphism with hepatitis C virus infection. (PubMed id 18041006)1, 4 Pereira F.A....Reis M.G. (J. Med. Virol. 2008)
    840. TNF-alpha polymorphisms are associated with obsessive-compulsive disorder. (PubMed id 18639610)1, 4 Hounie A.G....Miguel E.C. (Neurosci. Lett. 2008)
    841. Association of tumor necrosis factor-alpha -308G&gt;A polymorphism with IgE-mediated allergy to betalactams in an Italian population. (PubMed id 17471286)1, 4 GuAcant-Rodriguez R.M....Romano A. (Pharmacogenomics J. 2008)
    842. Assessment of genetic risk factors for thoracic aortic aneurysm in hypertensive patients. (PubMed id 18600213)1, 4 Kato K....Yamada Y. (Am. J. Hypertens. 2008)
    843. Interaction between interleukin-1beta -31T/C gene polymorphism and drinking and smoking habits on the risk of hepatocellular carcinoma among Japanese. (PubMed id 18603357)1, 4 Sakamoto T....Tanaka K. (Cancer Lett. 2008)
    844. Clinical and molecular-genetic markers of ADHD in children. (PubMed id 18580852)1, 4 Drtilkova I....Znojil V. (Neuro Endocrinol. Lett. 2008)
    845. Tumor necrosis factor (TNF)-TNF receptor gene polymorphisms and their serum levels in Korean women with endometriosis. (PubMed id 19238748)1, 4 Chae S.J....Kim J.G. (Am. J. Reprod. Immunol. 2008)
    846. [Genetics factors determining predisposition to chronic course of virus hepatitis and fibrosis in liver]. (PubMed id 18610831)1, 4 Goncharova I.A....Puzyrev V.P. (Mol. Biol. (Mosk.) 2008)
    847. Roles of TNF-alpha gene polymorphisms in the occurrence and progress of SARS-Cov infection: a case-control study. (PubMed id 18312678)1, 4 Wang S....Hui W. (BMC Infect. Dis. 2008)
    848. Inflammatory response gene polymorphisms and their relationship with colorectal cancer risk. (PubMed id 18433468)1, 4 Suchy J....LubiA8ski J. (BMC Cancer 2008)
    849. TNF polymorphisms in Lebanese patients with BehAset's disease. (PubMed id 19026135)1, 4 Arayssi T.K....Farra C.G. (Clin. Exp. Rheumatol. 2008)
    850. Inflammation-related genes and the risk of Parkinson's disease: a multilocus approach. (PubMed id 18284424)1, 4 Infante J....Combarros O. (Eur. J. Neurol. 2008)
    851. Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PubMed id 18676680)1, 4 Hosgood H.D....Lan Q. (Carcinogenesis 2008)
    852. Polymorphisms in the tumor necrosis factor alpha and interleukin 1-beta promoters with possible gene regulatory functions increase the risk of preterm birth. (PubMed id 18951205)1, 4 Hollegaard M.V....Hougaard D.M. (Acta Obstet Gynecol Scand 2008)
    853. Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort. (PubMed id 18426866)1, 4 Marvelle A.F....Mohlke K.L. (Diabetes 2008)
    854. Cytokine single nucleotide polymorphisms in Iranian populations. (PubMed id 18632425)1, 4 Amirzargar A.A....Nikbin B. (Eur. Cytokine Netw. 2008)
    855. The TNF (-308A) polymorphism is associated with microchimerism in transfused trauma patients. (PubMed id 18199828)1, 4 Gill R.M....Busch M.P. (Blood 2008)
    856. TNF polymorphisms and prostate cancer risk. (PubMed id 18196539)1, 4 Danforth K.N....Hsing A.W. (Prostate 2008)
    857. Polymorphisms of TNF-alpha and LT-alpha genes in multiple myeloma. (PubMed id 18405969)1, 4 KA!dA!r K....VA!rkonyi J. (Leuk. Res. 2008)
    858. Association of cytokine gene polymorphisms in CWP and its severity in Turkish coal workers. (PubMed id 18702109)1, 4 Ates I....Karakaya A. (Am. J. Ind. Med. 2008)
    859. Cytokine polymorphisms have a synergistic effect on severity of the acute sickness response to infection. (PubMed id 18937577)1, 4 Vollmer-Conna U....Lloyd A.R. (Clin. Infect. Dis. 2008)
    860. Lack of associations between several polymorphisms in cytokine genes and the risk of chronic obstructive pulmonary diseases in Taiwan. (PubMed id 18364273)1, 4 Hsieh M.H....Christiani D.C. (Kaohsiung J. Med. Sci. 2008)
    861. Ethnic differences in cytokine gene polymorphisms: potential implications for cancer development. (PubMed id 17618436)1, 4 Zabaleta J....Ochoa A.C. (Cancer Immunol. Immunother. 2008)
    862. TNF-alpha promoter polymorphisms in sudden infant death. (PubMed id 18571009)1, 4 Ferrante L....Rognum T.O. (Hum. Immunol. 2008)
    863. Association of chest radiography findings with host-related genetic factors in patients with nephropathia epidemica. (PubMed id 17907045)1, 4 Paakkala A....Mustonen J. (Scand. J. Infect. Dis. 2008)
    864. Absence of an association of tumor necrosis factor (TNF)-alpha G308A, interleukin-6 (IL-6) G174C and interleukin-10 (IL-10) G1082A polymorphism in women with preeclampsia. (PubMed id 17544514)1, 4 Stonek F....Philipp K. (J. Reprod. Immunol. 2008)
    865. Lack of association between cytokine gene polymorphisms and silicosis and pulmonary tuberculosis in Chinese iron miners. (PubMed id 18931463)1, 4 Wu F....Xia Z. (J Occup Health 2008)
    866. Does cytokine gene polymorphism affect steroid responses in idiopathic nephrotic syndrome? (PubMed id 19008611)1, 4 Tripathi G....Agrawal S. (Indian J Med Sci 2008)
    867. IL-6 receptor, IL-8 receptor and TNF-alpha238 (G/A) polymorphisms are not associated with BehAset's disease in patients of German or Turkish origin. (PubMed id 19026125)1, 4 Storz K....KAPtter I. (Clin. Exp. Rheumatol. 2008)
    868. Correlation between genetic polymorphism of cytokine genes, plasma protein levels and bronchial asthma in the Han people in northern China. (PubMed id 18773331)1, 4 Xiaomin L....Yingmei Z. (J Asthma 2008)
    869. Can tumor necrosis factor receptor II gene 676T&gt;G polymorphism predict the response grading to anti-TNFalpha therapy in rheumatoid arthritis? (PubMed id 18309487)1, 4 Ongaro A....Padovan M. (Rheumatol. Int. 2008)
    870. Tumour necrosis factor (-308A) polymorphism in pre-eclampsia: meta-analysis of 16 case-control studies. (PubMed id 19133041)1, 4 Bombell S. and McGuire W. (amp 2008)
    871. Frequency of concurrent autoimmune disorders in patients with autoimmune hepatitis: effect of age, gender, and genetic background. (PubMed id 18223493)1, 4 Bittencourt P.L....Carrilho F.J. (J. Clin. Gastroenterol. 2008)
    872. Host polymorphisms in interleukin 4, complement factor H, and C-reactive protein associated with nasal carriage of Staphylococcus aureus and occurrence of boils. (PubMed id 18422436)1, 4 Emonts M....Belkum A.v. (J. Infect. Dis. 2008)
    873. Influence of genetic factors on toluene diisocyanate-related symptoms: evidence from a cross-sectional study. (PubMed id 18447907)1, 4 Broberg K....Littorin M. (Environ Health 2008)
    874. Tumor necrosis factor SNP haplotypes are associated with iron deficiency anemia in West African children. (PubMed id 18716131)1, 4 Atkinson S.H....Prentice A.M. (Blood 2008)
    875. Cytokine gene polymorphism and postreperfusion syndrome during orthotopic liver transplantation. (PubMed id 18589089)1, 4 Ulukaya S....Ulukaya E. (Transplant. Proc. 2008)
    876. TNFalpha -308 C--&gt;t and -863 C--&gt;a polymorphisms and spermiogram characteristics. (PubMed id 18418000)1, 4 Kurz C....Pietrowski D. (Gynecol. Obstet. Invest. 2008)
    877. Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. (PubMed id 18583979)1, 4 Allen N.C....Bertram L. (Nat. Genet. 2008)
    878. Polymorphisms of the tumor necrosis factor-alpha (TNF) and the TNF-alpha converting enzyme (TACE/ADAM17) genes in relation to cardiovascular mortality: the AtheroGene study. (PubMed id 18600307)1, 4 Morange P.E....Tiret L. (J. Mol. Med. 2008)
    879. Genetic profiling of genes from the oxidative stress pathway among North and South Indians. (PubMed id 18720901)1, 4 Tiwari A.K....Thelma B.K. (Hum. Biol. 2008)
    880. Genetic analysis of tumor necrosis factor-alpha (TNF-alpha) G-308A and Saitohin Q7R polymorphisms with Alzheimer's disease. (PubMed id 18396294)1, 4 Wang B....Ma X. (J. Neurol. Sci. 2008)
    881. [Association of tumor necrosis factor-alpha gene polymorphisms with susceptibility to occupational stress]. (PubMed id 19257928)1, 4 Qiu Y. and Yu S.F. (Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2008)
    882. Genetic polymorphisms impact the risk of acute rejection in pediatric heart transplantation: a multi-institutional study. (PubMed id 18551071)1, 4 Girnita D.M....Zeevi A. (Transplantation 2008)
    883. Tumor necrosis factor-alpha -1031 T/C polymorphism is associated with smaller and more proatherogenic low density lipoprotein particles in patients with rheumatoid arthritis. (PubMed id 18634161)1, 4 VallvAc J.C....Masana L. (J. Rheumatol. 2008)
    884. Interleukin-1 and tumor necrosis factor-alpha gene polymorphisms in Turkish patients with localized aggressive periodontitis. (PubMed id 18587204)1, 4 Guzeldemir E....Tastan H. (J Oral Sci 2008)
    885. Multiple genetic factors in olanzapine-induced weight gain in schizophrenia patients: a cohort study. (PubMed id 19193342)1, 4 Ujike H....Kuroda S. (J Clin Psychiatry 2008)
    886. Association of tumour necrosis factor alpha (TNF-alpha) polymorphisms with Graves' disease: A meta-analysis. (PubMed id 18472000)1, 4 Li N....Chen X. (Clin. Biochem. 2008)
    887. Polymorphisms of TNF-enhancer and gene for FcgammaRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population. (PubMed id 18194515)1, 4 Sinha S....Habib S. (Malar. J. 2008)
    888. TNF promoter polymorphisms associated with muscle phenotypes in humans. (PubMed id 18635873)1, 4 Liu D....Roth S.M. (J. Appl. Physiol. 2008)
    889. Interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha) levels and IL-6, TNF-polymorphisms in children with thrombosis. (PubMed id 18176176)1, 4 Unal S....Gurgey A. (J. Pediatr. Hematol. Oncol. 2008)
    890. Tumor necrosis factor-alpha polymorphisms in ulcerative colitis-associated colorectal cancer. (PubMed id 18289203)1, 4 Garrity-Park M.M....Smyrk T.C. (Am. J. Gastroenterol. 2008)
    891. Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. (PubMed id 18660489)1, 4 Lu Y....Boer J.M. (J. Lipid Res. 2008)
    892. The involvement of IL-10, IL-6, IFN-gamma, TNF-alpha and TGF-beta gene polymorphisms among Turkish lung cancer patients. (PubMed id 17654453)1, 4 Colakogullari M....Oral H.B. (Cell Biochem. Funct. 2008)
    893. TNF-alpha gene polymorphism (-308G/A) and toxoplasmic retinochoroiditis. (PubMed id 18577652)1, 4 Cordeiro C.A....Teixeira A.L. (Br J Ophthalmol 2008)
    894. A genetic-demographic approach reveals male-specific association between survival and tumor necrosis factor (A/G)-308 polymorphism. (PubMed id 18511747)1, 4 Cardelli M....Franceschi C. (J. Gerontol. A Biol. Sci. Med. Sci. 2008)
    895. [Association of cytokine gene polymorphisms with cachexia related to sporadic female breast cancer]. (PubMed id 18953879)1, 4 Li F.N....Jiang G.M. (Zhonghua Yi Xue Za Zhi 2008)
    896. Association of tumor necrosis factor -308G/A promoter polymorphism with schizophrenia and bipolar affective disorder in a Polish population. (PubMed id 18515978)1, 4 Czerski P.M....Hauser J. (Neuropsychobiology 2008)
    897. A functional polymorphism of the TNF-alpha gene that is associated with type 2 DM. (PubMed id 18328809)1, 4 Susa S....Kato T. (Biochem. Biophys. Res. Commun. 2008)
    898. Association of pro/anti-inflammatory cytokine gene variants in renal transplant patients with allograft outcome and cyclosporine immunosuppressant levels. (PubMed id 19707465)1, 4 Manchanda P.K....Mittal R.D. (amp 2008)
    899. Cytokine gene polymorphisms and susceptibility to chronic irritant contact dermatitis. (PubMed id 18416756)1, 4 de Jongh C.M....Kezic S. (Contact Derm. 2008)
    900. Tumour-necrosis factor-A polymorphisms and gastric cancer risk: a meta-analysis. (PubMed id 18319718)1, 4 Gorouhi F....Kamangar F. (Br. J. Cancer 2008)
    901. Polymorphisms in genes encoding tumor necrosis factor-alpha and HLA-DRB1 are not associated with response to infliximab in patients with rheumatoid arthritis. (PubMed id 18176993)1, 4 Pinto J.A....Blanco F.J. (J. Rheumatol. 2008)
    902. Can we predict neuropathy risk before stavudine prescription in a resource-limited setting? (PubMed id 18834321)1, 4 Affandi J.S....Cherry C.L. (AIDS Res. Hum. Retroviruses 2008)
    903. IL-1beta (+3954C/T) polymorphism could protect human immunodeficiency virus (HIV)-infected patients on highly active antiretroviral treatment (HAART) against lipodystrophic syndrome. (PubMed id 18344712)1, 4 Asensi V....Valle-Garay E. (Genet. Med. 2008)
    904. Association between tumor necrosis factor-alpha gene promoter polymorphism at position -308 and acne in Turkish patients. (PubMed id 18615253)1, 4 Baz K....IkizoA9lu G. (Arch. Dermatol. Res. 2008)
    905. Cytokine gene polymorphisms in periodontal disease: a meta-analysis of 53 studies including 4178 cases and 4590 controls. (PubMed id 18673406)1, 4 Nikolopoulos G.K....Bagos P.G. (J. Clin. Periodontol. 2008)
    906. Variants of CARD15, TNFA and PTPN22 and susceptibility to Crohn's disease in the Czech population: high frequency of the CARD15 1007fs. (PubMed id 18489434)1, 4 Hradsky O....Cinek O. (Tissue Antigens 2008)
    907. The G-308A polymorphism of the TNF-alpha gene does not predict changes in cardiac function in response to medical therapy for idiopathic dilated cardiomyopathy. (PubMed id 18997986)1, 4 Brooksbank R....Woodiwiss A. (Cardiovasc J Afr 2008)
    908. Tumor necrosis factor alpha-308 gene polymorphism and pseudoexfoliation glaucoma. (PubMed id 18852869)1, 4 Tekeli O....Elhan A.H. (Mol. Vis. 2008)
    909. Association of cytokine gene polymorphisms with rate of decline in lung function. (PubMed id 18545091)1, 4 Yucesoy B....Burgess J.L. (J. Occup. Environ. Med. 2008)
    910. The sodium-dependent glucose cotransporter SLC5A11 as an autoimmune modifier gene in SLE. (PubMed id 18069935)1, 4 Tsai L.-J.... Lan J.-L. (Tissue Antigens 2008)
    911. TNFA locus is associated with beta degrees 39 thalassemia in Corsica and Sardinia. (PubMed id 19103526)1, 4 Giovannoni L. (Eur. Cytokine Netw. 2008)
    912. Racial disparity in maternal-fetal genetic epistasis in spontaneous preterm birth. (PubMed id 18538149)1, 4 Fortunato S.J....Williams S.M. (Am. J. Obstet. Gynecol. 2008)
    913. [Gene polymorphism of tumor necrosis factor-alpha promoter region in -308 site and premature births in Chinese Han populations]. (PubMed id 18095602)1, 4 Pu J. and Zeng W.Y. (Sichuan Da Xue Xue Bao Yi Xue Ban 2007)
    914. Novel interleukin-4 and interleukin-1 receptor antagonist gene variations associated with non-cardia gastric cancer in Japan: comprehensive analysis of 207 polymorphisms of 11 cytokine genes. (PubMed id 17444864)1, 4 Seno H....Chiba T. (J. Gastroenterol. Hepatol. 2007)
    915. H pylori seropositivity and cytokine gene polymorphisms. (PubMed id 17724799)1, 4 Saijo Y....Kishi R. (World J. Gastroenterol. 2007)
    916. Genetic polymorphisms of tumor necrosis factor-alpha modify the association between dietary polyunsaturated fatty acids and fasting HDL-cholesterol and apo A-I concentrations. (PubMed id 17823444)1, 4 Fontaine-Bisson B....El-Sohemy A. (Am. J. Clin. Nutr. 2007)
    917. Tumor necrosis factor alpha -308 polymorphism is associated with rheumatoid arthritis in Han population of Eastern China. (PubMed id 17710405)1, 4 Chen R....Sun S. (Rheumatol. Int. 2007)
    918. Sun exposure, vitamin D receptor gene polymorphisms and risk of non-Hodgkin lymphoma. (PubMed id 17653830)1, 4 Purdue M.P....Wang S.S. (amp 2007)
    919. Allograft inflammatory factor-1 and tumor necrosis factor single nucleotide polymorphisms in systemic sclerosis. (PubMed id 17498268)1, 4 Otieno F.G....Artlett C.M. (Tissue Antigens 2007)
    920. Relationship between iris constitution analysis and TNF-alpha gene polymorphism in hypertensives. (PubMed id 17708628)1, 4 Yoo C.S....Um J.Y. (Am. J. Chin. Med. 2007)
    921. Cytokine promoter polymorphisms in Taiwanese patients with Graves' disease. (PubMed id 17208210)1, 4 Shiau M.Y....Chang Y.H. (Clin. Biochem. 2007)
    922. Body mass, polymorphisms in obesity-related genes, and the risk of developing breast cancer among women with benign breast disease. (PubMed id 17428620)1, 4 Gallicchio L....Helzlsouer K.J. (Cancer Detect. Prev. 2007)
    923. Conditional likelihood methods for haplotype-based association analysis using matched case-control data. (PubMed id 18078481)1, 4 Chen J. and Rodriguez C. (Biometrics 2007)
    924. Gastric cancer susceptibility is not linked to pro-and anti-inflammatory cytokine gene polymorphisms in whites: a Nationwide Multicenter Study in Spain. (PubMed id 17640324)1, 4 GarcA-a-GonzA!lez M.A....Zaballa M. (Am. J. Gastroenterol. 2007)
    925. Risk factors for perianal Crohn's disease: the role of genotype, phenotype, and ethnicity. (PubMed id 17509030)1, 4 Karban A....Levine A. (Am. J. Gastroenterol. 2007)
    926. Association of cytokine genetic polymorphism with hepatitis B infection evolution in adult patients. (PubMed id 17612762)1, 4 Ribeiro C.S....Moliterno R.A. (Mem. Inst. Oswaldo Cruz 2007)
    927. Frequency of cytokine gene promoter polymorphisms in the Northern Ireland cystic fibrosis population. (PubMed id 17336597)1, 4 Watt A.P....Elborn J.S. (J. Cyst. Fibros. 2007)
    928. Association of tumor necrosis factor polymorphisms with Guillain-BarrAc syndrome. (PubMed id 17483581)1, 4 Zhang J....Guo L. (Eur. Neurol. 2007)
    929. Cytokine gene variants and venous thrombotic risk in the BRATROS (BRAZILIAN THROMBOSIS STUDY). (PubMed id 17113632)1, 4 Pieroni F....Franco R.F. (Thromb. Res. 2007)
    930. Polymorphisms in Th1-type cell-mediated response genes and risk of gastric cancer. (PubMed id 16885196)1, 4 Hou L....Chow W.H. (Carcinogenesis 2007)
    931. Influence of G308A polymorphism of tumor necrosis factor-alpha gene on inflammatory markers in postsurgical head and neck cancer patients with early enteral nutrition. (PubMed id 17560079)1, 4 de Luis D.A....Aller R. (Nutrition 2007)
    932. Tumour necrosis factor-alpha single nucleotide polymorphisms are not independent of HLA class I in UK Caucasians with adult onset idiopathic inflammatory myopathies. (PubMed id 17586554)1, 4 Chinoy H....Cooper R.G. (Rheumatology (Oxford) 2007)
    933. Tumor necrosis factor-alpha-308 gene polymorphism in Croatian and Slovenian multiple sclerosis patients. (PubMed id 17268200)1, 4 RistiA8 S....Peterlin B. (Eur. Neurol. 2007)
    934. Single nucleotide polymorphisms of tumor necrosis factor-alpha and the susceptibility to bronchopulmonary dysplasia. (PubMed id 17123322)1, 4 Strassberg S.S....Parton L.A. (Pediatr. Pulmonol. 2007)
    935. Do TNFA -308 G/A and IL6 -174 G/C gene polymorphisms modulate risk of gallbladder cancer in the north Indian population? (PubMed id 18260730)1, 4 Vishnoi M....Mittal B. (Asian Pac. J. Cancer Prev. 2007)
    936. Association of tumour necrosis factor alpha promoter polymorphisms with ankylosing spondylitis in Taiwan. (PubMed id 17360787)1, 4 Shiau M.Y....Chang Y.H. (Ann. Rheum. Dis. 2007)
    937. TNF microsatellite alleles in Brazilian Chagasic patients. (PubMed id 17712635)1, 4 Campelo V....Donadi E.A. (Dig. Dis. Sci. 2007)
    938. Contribution of 20 single nucleotide polymorphisms of 13 genes to dyslipidemia associated with antiretroviral therapy. (PubMed id 17700364)1, 4 Arnedo M....Tarr P.E. (Pharmacogenet. Genomics 2007)
    939. Confirmation of an association between the TNF(-308) promoter polymorphism and stroke risk in children with sickle cell anemia. (PubMed id 17600229)1, 4 Hoppe C....Styles L. ( a journal of cerebral circulation 2007)
    940. Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. (PubMed id 17192785)1, 4 Bertram L....Tanzi R.E. (Nat. Genet. 2007)
    941. TNF polymorphisms modify endotoxin exposure-associated longitudinal lung function decline. (PubMed id 17332138)1, 4 Zhang H....Christiani D.C. (Occup Environ Med 2007)
    942. TNF-alpha -308G&gt;A polymorphism modulates cytokine serum concentrations and macrovascular complications in diabetic patients on aspirin. (PubMed id 17516296)1, 4 Krayenbuehl P.A....Schulthess G. (amp 2007)
    943. Different effects of polymorphisms of tumor necrosis factor-alpha and interleukin-1 beta on development of peptic ulcer and gastric cancer. (PubMed id 17201881)1, 4 Sugimoto M....Hishida A. (J. Gastroenterol. Hepatol. 2007)
    944. GvHD-associated cytokine polymorphisms do not associate with Omenn syndrome rather than T-B- SCID in patients with defects in RAG genes. (PubMed id 17572155)1, 4 Haq I.J....Gennery A.R. (Clin. Immunol. 2007)
    945. Polymorphisms of the TNF-alpha gene and risk of celiac disease in T1DM children. (PubMed id 17550423)1, 4 Hermann C....MadA!csy L. (Pediatr Diabetes 2007)
    946. Host cytokine genotype is related to adverse prognosis and systemic inflammation in gastro-oesophageal cancer. (PubMed id 17103073)1, 4 Deans C....Fearon K. (Ann. Surg. Oncol. 2007)
    947. TNF alpha and NRAMP1 polymorphisms in leprosy. (PubMed id 17624216)1, 4 Vejbaesya S....Sermduangprateep C. (J Med Assoc Thai 2007)
    948. Tumor necrosis factor-alpha gene and cerebral aneurysms. (PubMed id 17415203)1, 4 Fontanella M....Pinessi L. (Neurosurgery 2007)
    949. Is tumor necrosis factor-376A promoter polymorphism associated with susceptibility to multiple sclerosis? (PubMed id 18051225)1, 4 Kauffman M.A....Villa A.M. (Medicina (B Aires) 2007)
    950. [The genetic polymorphism of cytokine genes in Zhejiang Han individuals]. (PubMed id 17369174)1, 4 Zhang W....Yan L.X. (Yi Chuan 2007)
    951. Genetic polymorphisms of macrophage-mediators in Guillain-BarrAc syndrome. (PubMed id 17761309)1, 4 Geleijns K....Jacobs B.C. (J. Neuroimmunol. 2007)
    952. Role of matrix metalloproteinase, tissue inhibitor of metalloproteinase and tumor necrosis factor-alpha single nucleotide gene polymorphisms in inflammatory bowel disease. (PubMed id 17589947)1, 4 Meijer M.J....Verspaget H.W. (World J. Gastroenterol. 2007)
    953. Genetic variability of major inflammatory mediators has no impact on the outcome of kidney transplantation. (PubMed id 17989610)1, 4 Brabcova I....ViklickA1 O. (Transplantation 2007)
    954. Association between a polymorphism in the lymphotoxin-a promoter region and migraine. (PubMed id 17635597)1, 4 Lee K.A....Chung C.S. (Headache 2007)
    955. Profile of cytokine gene polymorphisms in Iranian multiple sclerosis patients. (PubMed id 17439892)1, 4 Amirzargar A....Nikbin B. (Mult. Scler. 2007)
    956. Investigation of functional gene polymorphisms IL-1beta, IL-6, IL-10 and TNF-alpha in individuals with recurrent aphthous stomatitis. (PubMed id 17052682)1, 4 GuimarALes A.L....Gomez R.S. (Arch. Oral Biol. 2007)
    957. Genetic analyses of celiac disease in a Spanish population confirm association with CELIAC3 but not with CELIAC4. (PubMed id 17767555)1, 4 Capilla A....Palau F. (Tissue Antigens 2007)
    958. TNF-alpha, TNF-beta, IL-6, IL-10, PECAM-1 and the MPO inflammatory gene polymorphisms in osteosarcoma. (PubMed id 17483704)1, 4 Oliveira I.D....de Toledo S.R. (J. Pediatr. Hematol. Oncol. 2007)
    959. Vesicoureteric reflux and tumor necrosis factor-alpha gene polymorphism. (PubMed id 18947693)1, 4 Pardo R....Coto E. (J Pediatr Urol 2007)
    960. Association of human leukocyte antigen ancestral haplotype 8.1 with adverse outcome of non-Hodgkin's lymphoma. (PubMed id 17311253)1, 4 Nowak J....Warzocha K. (amp 2007)
    961. The polymorphism -863C/A in tumour necrosis factor-alpha gene contributes an independent association to gout. (PubMed id 17938134)1, 4 Chang S.J....Ko Y.C. (Rheumatology (Oxford) 2007)
    962. Genetic polymorphisms and the risk of infection following esophagectomy. positive association with TNF-alpha gene -308 genotype. (PubMed id 17592300)1, 4 Azim K....Reynolds J.V. (Ann. Surg. 2007)
    963. Two critical genes (HLA-DRB1 and ABCF1)in the HLA region are associated with the susceptibility to autoimmune pancreatitis. (PubMed id 17119950)1, 4 Ota M....Kawa S. (Immunogenetics 2007)
    964. Polymorphisms in the tumor necrosis factor-alpha gene in Turkish women with pre-eclampsia and eclampsia. (PubMed id 17593951)1, 4 PazarbaA9i A....GA1rtunAs E. (Acta Med. Okayama 2007)
    965. Proinflammatory cytokine single nucleotide polymorphisms in nasal polyposis. (PubMed id 17638785)1, 4 Erbek S.S....Cakmak O. (amp 2007)
    966. A suggestive association of fuchs heterochromic cyclitis with cytotoxic T cell antigen 4 gene polymorphism. (PubMed id 17287608)1, 4 Spriewald B.M....Wenkel H. (Ophthalmic Res. 2007)
    967. [Association between genetic polymorphism of tumor necrosis factor and chronic severe hepatitis B in patients]. (PubMed id 17988528)1, 4 Li Z....Li H. (Zhonghua Yi Xue Za Zhi 2007)
    968. Association of IL-10 and TNFalpha genotypes with ANCA appearance in ulcerative colitis. (PubMed id 17070109)1, 4 Castro-Santos P....Gutierrez C. (Clin. Immunol. 2007)
    969. [Polymorphisms of tumor necrosis factor genes in sporadic and hereditary breast cancer]. (PubMed id 18416134)1, 4 Malivanova T.F....Mazurenko N.N. (Vopr Onkol 2007)
    970. Polymorphisms in proinflammatory genes and susceptibility to typhoid fever and paratyphoid fever. (PubMed id 17477815)1, 4 Ali S....van Dissel J.T. (amp 2007)
    971. The tumor necrosis factor alpha -308 G/A polymorphism does not influence inflammation and coagulation response in human endotoxemia. (PubMed id 17304103)1, 4 Kovar F.M....Endler G. (Shock 2007)
    972. TNFa microsatellite polymorphism modulates the risk of type 1 diabetes in the Belgian population, independent of HLA-DQ. (PubMed id 17678725)1, 4 Aminkeng F....Van der Auwera B.J. (Hum. Immunol. 2007)
    973. Variable number of tandem repeats of TNF receptor type 2 promoter as genetic biomarker of susceptibility to develop invasive pulmonary aspergillosis. (PubMed id 17207711)1, 4 Sainz J....Jurado M. (Hum. Immunol. 2007)
    974. Genetic risk profiles for Alzheimer's disease: integration of APOE genotype and variants that up-regulate inflammation. (PubMed id 16930778)1, 4 Licastro F....Corder E.H. (Neurobiol. Aging 2007)
    975. Cytokine gene polymorphisms in hepatitis C virus-related oral lichen planus. (PubMed id 17697145)1, 4 Carrozzo M....Amoroso A. (Exp. Dermatol. 2007)
    976. Polygenic disease associations in thymomatous myasthenia gravis. (PubMed id 18071035)1, 4 Amdahl C....Skeie G.O. (Arch. Neurol. 2007)
    977. The TNF-alpha-238G &gt; a single-nucleotide polymorphism protects against memory decline in older adults with type 2 diabetes. (PubMed id 17592954)1, 4 Chui M.H....Greenwood C.E. (Behav. Neurosci. 2007)
    978. Strong protective effect of DR3 against ulcerative colitis in the Spanish population. (PubMed id 17714554)1, 4 GA^mez-GarcA-a M....MartA-nez A. (Am. J. Gastroenterol. 2007)
    979. TNFA-308G&gt;A polymorphism influences the TNF-alpha response to altered vaginal flora. (PubMed id 17123692)1, 4 GenAs M.R....Onderdonk A.B. (Eur. J. Obstet. Gynecol. Reprod. Biol. 2007)
    980. Association of tumor necrosis factor-alpha-238G&gt;A and apolipoprotein E2 polymorphisms with intracranial hemorrhage after brain arteriovenous malformation treatment. (PubMed id 17986934)1, 4 Achrol A.S....Young W.L. (Neurosurgery 2007)
    981. Rheumatoid arthritis and genetic markers in Syrian and French populations: different effect of the shared epitope. (PubMed id 17068065)1, 4 Kazkaz L....Miossec P. (Ann. Rheum. Dis. 2007)
    982. Cytokine polymorphisms and risk of infection after kidney transplantation. (PubMed id 17889143)1, 4 Rodrigo E....Arias M. (Transplant. Proc. 2007)
    983. Possible involvement of cytokine gene polymorphisms in fulminant hepatitis. (PubMed id 17559370)1, 4 Takakura M....Shiratori K. (J. Gastroenterol. Hepatol. 2007)
    984. Evidence for genetic susceptibility towards development of posttransplant lymphoproliferative disorder in solid organ recipients. (PubMed id 17700165)1, 4 Babel N....Reinke P. (Transplantation 2007)
    985. Cytokine gene polymorphisms in Italian preterm infants: association between interleukin-10 -1082 G/A polymorphism and respiratory distress syndrome. (PubMed id 17314689)1, 4 Capasso M....Iolascon A. (Pediatr. Res. 2007)
    986. Gene polymorphisms of TNF-alpha(-308), IL-10(-1082), IL-6(-174), and IL-1Ra(VNTR) related to susceptibility and severity of rheumatic heart disease. (PubMed id 17607501)1, 4 Settin A....Saber I. (Pediatr Cardiol 2007)
    987. T-cell regulatory gene CTLA-4 polymorphism/haplotype association with autoimmune pancreatitis. (PubMed id 17712006)1, 4 Chang M.C....Wong J.M. (Clin. Chem. 2007)
    988. Tumor necrosis factor-alpha promoter polymorphism is associated with the risk of Parkinson's disease. (PubMed id 17192953)1, 4 Wu Y.R....Chen C.M. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2007)
    989. Clarithromycin resistance, tumor necrosis factor alpha gene polymorphism and mucosal inflammation affect H. pylori eradication success. (PubMed id 17846855)1, 4 Zambon C.F....Pedrazzoli S. (J. Gastrointest. Surg. 2007)
    990. Genetic variation at the TNF locus and the risk of severe sequelae of ocular Chlamydia trachomatis infection in Gambians. (PubMed id 17330135)1, 4 Natividad A....Bailey R.L. (Genes Immun. 2007)
    991. Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes. (PubMed id 17192490)1, 4 Willer C.J....Boehnke M. (Diabetes 2007)
    992. TNFalpha-308G/A polymorphism as a risk factor for HPV associated cervical cancer in Indian population. (PubMed id 17452777)1, 4 Kohaar I....Bharadwaj M. (Cell. Oncol. 2007)
    993. Acute myocardial infarction and proinflammatory gene variants. (PubMed id 18056971)1, 4 Licastro F....Corder E.H. (Ann. N. Y. Acad. Sci. 2007)
    994. TNFA2 and d2 alleles of the tumor necrosis factor alpha gene polymorphism are associated with onset/occurrence of idiopathic membranous nephropathy. (PubMed id 17213876)1, 4 Thibaudin D....Berthoux F. (Kidney Int. 2007)
    995. Cytokine genes and pain severity in lung cancer: exploring the influence of TNF-alpha-308 G/A IL6-174G/C and IL8-251T/A. (PubMed id 18086782)1, 4 Reyes-Gibby C.C....Shete S. (amp 2007)
    996. [Association of tumor necrosis factor alpha 308 G/A gene promoter polymorphism with the presence of chronic obstructive pulmonary disease: a meta-analysis]. (PubMed id 17988552)1, 4 Hu G.P....Ran P.X. (Zhonghua Jie He He Hu Xi Za Zhi 2007)
    997. Analysis of C-850T and G-308A polymorphisms of the tumor necrosis factor-alpha gene in Maya-Mestizo women with preeclampsia. (PubMed id 17710577)1, 4 Canto-Cetina T....Canto P. (Hypertens Pregnancy 2007)
    998. Relevance of transforming growth factor-beta1, interleukin-8, and tumor necrosis factor-alpha polymorphisms in patients with chronic pancreatitis. (PubMed id 17400536)1, 4 Farkas G....MA!ndi Y. (Eur. Cytokine Netw. 2007)
    999. Serological and genetic factors in early recurrence of IgA nephropathy after renal transplantation. (PubMed id 17988266)1, 4 Coppo R....Ponticelli C. (Clin Transplant 2007)
    1000. Genetic variation in tumour necrosis factor and lymphotoxin is not associated with endometriosis in an Australian sample. (PubMed id 17595314)1, 4 Zhao Z.Z....Montgomery G.W. (Hum. Reprod. 2007)
    1001. Polymorphisms in pro- and anti-inflammatory cytokine genes and susceptibility to atherosclerosis: a pathological study of 1503 consecutive autopsy cases. (PubMed id 17213232)1, 4 Oda K....Sawabe M. (Hum. Mol. Genet. 2007)
    1002. Lack of association of tumor necrosis factor-alpha polymorphisms with Chagas disease in Brazilian patients. (PubMed id 17141882)1, 4 Drigo S.A....Goldberg A.C. (Immunol. Lett. 2007)
    1003. Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population. (PubMed id 17355643)1, 4 Huang H.Y....Helzlsouer K.J. (BMC Genet. 2007)
    1004. Cytokine gene polymorphisms in acquired bone marrow failure. (PubMed id 17373677)1, 4 Gidvani V....Young N.S. (Am. J. Hematol. 2007)
    1005. TNF receptor I polymorphism is associated with persistent palindromic rheumatism. (PubMed id 17763205)1, 4 Lu L.Y....Sung P.K. (Scand. J. Rheumatol. 2007)
    1006. Cytokine gene polymorphisms in Chinese patients with psoriasis. (PubMed id 17388919)1, 4 Chang Y.T....Tsai S.F. (Br. J. Dermatol. 2007)
    1007. Association and interaction of the TNF-alpha gene with other pro- and anti-inflammatory cytokine genes and HLA genes in patients with type 1 diabetes from North India. (PubMed id 17498265)1, 4 Kumar R....Rani R. (Tissue Antigens 2007)
    1008. Associations between serum C-reactive protein (CRP) levels and polymorphisms of CRP, interleukin 1B, and tumor necrosis factor genes among Japanese health checkup examinees. (PubMed id 17477779)1, 4 Kikuchi M....Hamajima N. (Asian Pac. J. Cancer Prev. 2007)
    1009. Investigation of functional gene polymorphisms interleukin-1beta, interleukin-6, interleukin-10 and tumor necrosis factor in individuals with oral lichen planus. (PubMed id 17686006)1, 4 Xavier G.M....Gomez R.S. (amp 2007)
    1010. Polymorphisms of interleukin-10 and tumour necrosis factor-alpha genes are associated with newly diagnosed and recurrent pulmonary tuberculosis. (PubMed id 17587429)1, 4 Oh J.H....Song C.H. (Respirology 2007)
    1011. Polymorphisms within the IL-1 gene cluster: effects on cytokine profiles in peripheral blood and whole blood cell cultures of patients with aggressive periodontitis, juvenile idiopathic arthritis, and rheumatoid arthritis. (PubMed id 17335371)1, 4 Havemose-Poulsen A....Holmstrup P. (J. Periodontol. 2007)
    1012. Identification of two independent risk factors for lupus within the MHC in United Kingdom families. (PubMed id 17997607)1, 4 Fernando M.M....Vyse T.J. (PLoS Genet. 2007)
    1013. TNF microsatellites polymorphism is associated with rheumatoid arthritis. Confirming evidence in northwestern Colombians. (PubMed id 17631742)1, 4 Gomez L.M....Anaya J.M. (Clin. Exp. Rheumatol. 2007)
    1014. Susceptibility genes in Graves' ophthalmopathy: searching for a needle in a haystack? (PubMed id 17521325)1, 4 Bednarczuk T....Wall J.R. (Clin. Endocrinol. (Oxf) 2007)
    1015. Tumour necrotizing factor-alpha promoter and GST-T1 genotype predict skin allergy to chromate in cement workers in Taiwan. (PubMed id 17937745)1, 4 Wang B.J....Guo Y.L. (Contact Derm. 2007)
    1016. A TNF region haplotype offers protection from typhoid fever in Vietnamese patients. (PubMed id 17503085)1, 4 Dunstan S.J....Farrar J.J. (Hum. Genet. 2007)
    1017. Association of CD14, IL1B, IL6, IL10 and TNFA functional gene polymorphisms with symptomatic dental abscesses. (PubMed id 17511783)1, 4 de SA! A.R....Gomez R.S. (Int Endod J 2007)
    1018. Inflammation and atherosclerosis: the role of TNF and TNF receptors polymorphisms in coronary artery disease. (PubMed id 17346438)1, 4 Sbarsi I....Cuccia M. (Int J Immunopathol Pharmacol 2007)
    1019. Inflammatory cytokine gene polymorphisms and increased risk of Parkinson disease. (PubMed id 17562931)1, 4 Wahner A.D....Ritz B. (Arch. Neurol. 2007)
    1020. No association between the tumor necrosis factor-alpha gene promoter polymorphisms and schizophrenia in a Japanese population. (PubMed id 17559942)1, 4 Watanabe Y....Someya T. (Psychiatry Res 2007)
    1021. Effect of the G-308A polymorphism of the tumor necrosis factor alpha gene on the risk of ischemic heart disease and ischemic stroke: a meta-analysis. (PubMed id 17452160)1, 4 Pereira T.V....Krieger J.E. (Am. Heart J. 2007)
    1022. Impact of serum levels and gene polymorphism of cytokines on chronic hepatitis C infection. (PubMed id 17656331)1, 4 Chen T.Y....Chiou H.L. (Transl Res 2007)
    1023. The novel -G646A polymorphism of the TNFalpha promoter is associated with the HLA-B51 allele in Korean patients with BehAset's disease. (PubMed id 17657677)1, 4 Chang H.K....Kim S.K. (Scand. J. Rheumatol. 2007)
    1024. Contribution for new genetic markers of rheumatoid arthritis activity and severity: sequencing of the tumor necrosis factor-alpha gene promoter. (PubMed id 17408492)1, 4 Fonseca J.E....Queiroz M.V. (amp 2007)
    1025. Gene polymorphisms and the prevalence of key periodontal pathogens. (PubMed id 17452560)1, 4 Nibali L....Griffiths G.S. (J. Dent. Res. 2007)
    1026. Genetic polymorphisms in alveolar macrophage response-related genes, and risk of silicosis and pulmonary tuberculosis in Chinese iron miners. (PubMed id 17223386)1, 4 Qu Y....Xia Z. (Int J Hyg Environ Health 2007)
    1027. Tumor necrosis factor-alpha 308.2 polymorphism is associated with advanced hepatic fibrosis and higher risk for hepatocellular carcinoma. (PubMed id 18030367)1, 4 Jeng J.E....Chang J.G. (Neoplasia 2007)
    1028. TNF alpha promoter polymorphisms analysis in benign and malignant breast lesions. (PubMed id 17234183)1, 4 Sirotkovic-Skerlev M....Kapitanovic S. (Exp. Mol. Pathol. 2007)
    1029. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. (PubMed id 17703412)1, 4 Janssen R....Hoebee B. (J. Infect. Dis. 2007)
    1030. Lack of association between genetic polymorphisms in cytokine genes and disease expression in patients with hereditary non-polyposis colorectal cancer. (PubMed id 17454884)1, 4 Talseth B.A....Scott R.J. (Scand. J. Gastroenterol. 2007)
    1031. Common variants in genes that mediate immunity and risk of multiple myeloma. (PubMed id 17315188)1, 4 Brown E.E....Baris D. (Int. J. Cancer 2007)
    1032. Tumour necrosis factor a -308 promoter polymorphism in patients with rheumatoid arthritis. (PubMed id 17763852)1, 4 Rezaieyazdi Z....Mohajer F. (Rheumatol. Int. 2007)
    1033. Polymorphism in cytokine genes as prognostic markers in Hodgkin's lymphoma. (PubMed id 17496310)1, 4 Hohaus S....Leone G. (Ann. Oncol. 2007)
    1034. TNF-alpha polymorphisms in chronic beryllium disease and beryllium sensitization. (PubMed id 17426528)1, 4 McCanlies E.C....Weston A. (J. Occup. Environ. Med. 2007)
    1035. A tumor necrosis factor-alpha promoter polymorphism and pregnancy complications: results of a prospective cohort study in 1652 pregnant women. (PubMed id 17913961)1, 4 Stonek F....Tempfer C.B. (Reprod Sci 2007)
    1036. A case-control investigation of immune function gene polymorphisms and risk of testicular germ cell tumors. (PubMed id 17220333)1, 4 Purdue M.P....McGlynn K.A. (amp 2007)
    1037. Investigation of functional gene polymorphisms: IL-1B, IL-6 and TNFA in benign migratory glossitis in Brazilian individuals. (PubMed id 17850436)1, 4 GuimarALes A.L....Gomez R.S. (amp 2007)
    1038. Tumour necrosis factor gene complex polymorphisms in chronic obstructive pulmonary disease. (PubMed id 16867312)1, 4 Ruse C.E....Wardlaw A.J. (Respir Med 2007)
    1039. Combination of Helicobacter pylori strain and tumor necrosis factor-alpha polymorphism of the host increases the risk of peptic ulcer disease in children. (PubMed id 17667716)1, 4 Wilschanski M....Halle D. (J. Pediatr. Gastroenterol. Nutr. 2007)
    1040. Genetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF-LTA) and breast cancer risk. (PubMed id 17216494)1, 4 Gaudet M.M....Garcia-Closas M. (Hum. Genet. 2007)
    1041. Reduced mortality and CD4 cell loss among carriers of the interleukin-10 -1082G allele in a Zimbabwean cohort of HIV-1-infected adults. (PubMed id 18090276)1, 4 Erikstrup C....Ullum H. (AIDS 2007)
    1042. Tumor necrosis factor promoter gene polymorphism associated with increased susceptibility to non-Hodgkin's lymphomas. (PubMed id 17087739)1, 4 Bel Hadj Jrad B....Chouchane L. (Eur. J. Haematol. 2007)
    1043. Tumor necrosis factor-alpha promoter -308 A/G polymorphism and rheumatoid arthritis susceptibility: a metaanalysis. (PubMed id 17143972)1, 4 Lee Y.H....Song G.G. (J. Rheumatol. 2007)
    1044. [Relationship between cytokine gene polymorphism and development of gastric adenocarcinoma]. (PubMed id 17672967)1, 4 Zeng Q.D....Wang Y.S. (Zhonghua Yi Xue Za Zhi 2007)
    1045. Cytokine gene polymorphisms are not associated with bronchiolitis obliterans syndrome or survival after lung transplant. (PubMed id 17097497)1, 4 Snyder L.D....Palmer S.M. (J. Heart Lung Transplant. 2006)
    1046. IL-1beta, IL-6 and TNF-alpha and outcomes of neonatal hypoxic ischemic encephalopathy. (PubMed id 16181755)1, 4 Aly H....Hasanein B.M. (amp 2006)
    1047. A first study of cytokine genomic polymorphisms in CFS: Positive association of TNF-857 and IFNgamma 874 rare alleles. (PubMed id 16762155)1, 4 Carlo-Stella N....Cuccia M. (Clin. Exp. Rheumatol. 2006)
    1048. Role of non-HLA genetic polymorphisms in graft-versus-host disease after haematopoietic stem cell transplantation. (PubMed id 16984283)1, 4 Bertinetto F.E....Amoroso A. (Int. J. Immunogenet. 2006)
    1049. Gene polymorphisms in patients below 35 years of age who underwent coronary artery bypass surgery. (PubMed id 16374139)1, 4 TA1tA1n U....KatircioA9lu S.F. (Coron. Artery Dis. 2006)
    1050. Cytokine genotyping in preeclampsia. (PubMed id 16433832)1, 4 Daher S....Mattar R. (Am. J. Reprod. Immunol. 2006)
    1051. Tumor necrosis factor-alpha genetic predisposing factors can influence clinical severity in nephropathia epidemica. (PubMed id 16987073)1, 4 Maes P....Van Ranst M. (Viral Immunol. 2006)
    1052. Single nucleotide polymorphisms in the interleukin-6 gene promoter, tumor necrosis factor-alpha gene promoter, and transforming growth factor-beta1 gene signal sequence as predictors of time to onset of aseptic loosening after total hip arthroplasty: preliminary study. (PubMed id 17139467)1, 4 KolundziA8 R....Troselj K.G. (J Orthop Sci 2006)
    1053. Association of TNF-alpha promoter polymorphisms with the outcomes of hepatitis B virus infection in Chinese Han population. (PubMed id 16907849)1, 4 Du T....Li H. (J. Viral Hepat. 2006)
    1054. Tumor necrosis factor-alpha gene G-308A polymorphism is a risk factor for the development of membranous glomerulonephritis. (PubMed id 16391465)1, 4 Bantis C....Ivens K. (Am. J. Nephrol. 2006)
    1055. Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. (PubMed id 16538176)1, 4 Hung S.I....Chen Y.T. (Pharmacogenet. Genomics 2006)
    1056. Timing of adequate antibiotic therapy is a greater determinant of outcome than are TNF and IL-10 polymorphisms in patients with sepsis. (PubMed id 16859504)1, 4 Garnacho-Montero J....Ortiz-Leyba C. (Crit Care 2006)
    1057. Association of the OGG1 Ser326Cys polymorphism with tooth loss. (PubMed id 16538639)1, 4 Hasui Y....Hinoda Y. (J. Clin. Lab. Anal. 2006)
    1058. Association study of the tumor necrosis factor-alpha gene and its 1A receptor gene with methamphetamine dependence. (PubMed id 17105909)1, 4 Nomura A....Kuroda S. (Ann. N. Y. Acad. Sci. 2006)
    1059. Association between non-Hodgkin lymphoma and haplotypes in the TNF region. (PubMed id 16643431)1, 4 Spink C.F....Morgan G.J. (Br. J. Haematol. 2006)
    1060. TNFa-e microsatellite, HLA-DRB1 and -DQB1 alleles and haplotypes in Brazilian patients presenting recently diagnosed type 1 diabetes mellitus. (PubMed id 17130569)1, 4 Rassi D.M....Donadi E.A. (Ann. N. Y. Acad. Sci. 2006)
    1061. Interaction analysis between 5-HTTLPR and TNFA -238/-308 polymorphisms in schizophrenia. (PubMed id 16252073)1, 4<