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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TNF Gene

protein-coding   GIFtS: 72
GCID: GC06P031543

tumor necrosis factor

(Previous names: tumor necrosis factor (TNF superfamily, member 2) )
(Previous symbol: TNFA)
 Explore 783 diseases affiliated with
TNF via our new
 Human Malady Compendium 
Biological research products
for TNF
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Tumor Necrosis Factor1 2     Tumor Necrosis Factor (TNF Superfamily, Member 2)1
TNFA1 2 3 5     APC1 Protein2
TNF-Alpha1     Cachectin3
TNFSF21 2 3     TNF, Macrophage-Derived2
DIF1 2     TNF, Monocyte-Derived2
Tumor Necrosis Factor Ligand Superfamily Member 22 3     Tumor Necrosis Factor-Alpha2
TNF-A1     Cachectin3

External Ids:    HGNC: 118921   Entrez Gene: 71242   Ensembl: ENSG000002328107   OMIM: 1911605   UniProtKB: P013753   

Export aliases for TNF gene to outside databases

Previous GC identifers: GC06P031606 GC06P031597 GC06P031314 GC06P031647 GC06P031652 GC06P031330


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TNF:
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF)
superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors
TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological
processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine
has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout
studies in mice also suggested the neuroprotective function of this cytokine. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: TNFA_HUMAN, P01375
Function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce
cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of
interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell
proliferation and induce cell differentiation
Function: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells

summary for TNF:
NF-kappaB (nuclear factor-kappa B) is a rapidly acting primary transcription factor found in all cell types.
It is involved in cellular responses to stimuli such as cytokines and stress and plays a key role in
regulating the immune response to infection. In unstimulated cells NF-kappaB dimers are sequestered
inactively in the cytoplasm by a protein complex called inhibitor of kappa B (IkappaB). IkappaB inactivates
NF-kappaB by masking the nuclear localization signals (NLS). Activation of NF-kappaB occurs via degradation
of IkappaB, a process that is initiated by its phosphorylation by IkappaB kinase (IKK). Phosphorylated
IkappaB becomes dissociated from NF-kappaB, unmasking the NLS. Phosphorylation also results in IkappaB
ubiquitination and targeting to the proteasome. NF-kappaB can now enter the nucleus and regulate gene
expression. NF-kappaB turns on expression of IkappaB forming a negative feedback loop.

Gene Wiki entry for TNF (Tumor necrosis factor-alpha)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  NT_113891.2  NT_167244.1  NT_167245.1  NT_167246.1  NT_167247.1  
NT_167248.1  NT_167249.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TNF gene promoter:
         c-Fos   p53   AP-1   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): TNF promoter sequence
   Search SABiosciences Chromatin IP Primers for TNF

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TNF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p21.33   HGNC cytogenetic band: 6p21.3

TNF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TNF gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P031543:  view genomic region     (about GC identifiers)

Start:
31,543,344 bp from pter      End:
31,546,113 bp from pter
Size:
2,770 bases      Orientation:
plus strand

6/7 alternative locations (see all 7):
Chr6+,ALT_REF_LOCI_1 31,555,632-31,565,733      Chr6+,ALT_REF_LOCI_4 31,505,893-31,508,655      Chr6+,ALT_REF_LOCI_3 31,525,488-31,539,294     
Chr6+,ALT_REF_LOCI_2 31,530,756-31,572,712      Chr6+,ALT_REF_LOCI_5 31,534,479-31,537,241      Chr6+,ALT_REF_LOCI_6 31,533,585-31,571,936     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TNFA_HUMAN, P01375 (See protein sequence)
Recommended Name: Tumor necrosis factor precursor  
Size: 233 amino acids; 25644 Da
Subunit: Homotrimer. Interacts with SPPL2B
Subcellular location: Cell membrane; Single-pass type II membrane protein
Subcellular location: Tumor necrosis factor, membrane form: Membrane; Single-pass type II membrane protein
Subcellular location: Tumor necrosis factor, soluble form: Secreted
Subcellular location: C-domain 1: Secreted
Subcellular location: C-domain 2: Secreted
Sequence caution: Sequence=AAF71992.1; Type=Frameshift; Positions=91, 157; Sequence=CAA75070.1; Type=Erroneous gene
model prediction;
6/12 PDB 3D structures from and Proteopedia for TNF (see all 12):
1A8M (3D)        1TNF (3D)        2AZ5 (3D)        2E7A (3D)        2TUN (3D)        2ZJC (3D)    
Secondary accessions: O43647 Q9P1Q2 Q9UIV3

Explore the universe of human proteins at neXtProt for TNF: NX_P01375

Post-translational modifications:

  • The soluble form derives from the membrane form by proteolytic processing. The membrane-bound form is further
  • proteolytically processed by SPPL2A or SPPL2B through regulated intramembrane proteolysis producing TNF intracellular
    domains (ICD1 and ICD2) released in the cytosol and TNF C-domain 1 and C-domain 2 secreted into the extracellular
    space1
  • The membrane form, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the membrane
  • form occurs by binding to soluble TNFRSF1A/TNFR11
  • O-glycosylated; glycans contain galactose, N-acetylgalactosamine and N-acetylneuraminic acid1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P01375

  • TNF Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_000585.2  
    ENSEMBL proteins: 
     ENSP00000398698  
    Reactome Protein details: P01375
    Human Recombinant Protein Products: 
    EMD Millipore Purified and/or Recombinant TNF Protein
    R&D Systems Recombinant & Natural Proteins for TNF (TNF-alpha/TNFSF1A)
    Enzo Life Sciences proteins for TNF
    OriGene Purified Proteins (see all 3): TNF
    OriGene Protein Over-expression Lysate: TNF
    OriGene Custom Protein Services for TNF 
    GenScript Purified and Recombinant Proteins for TNF
    Novus Biologicals TNF Proteins
    Novus Biologicals TNF Lysate
    Sino Biological Recombinant Protein for TNF
    ProSpec Recombinant Protein for TNF
    Browse Proteins at Uscn

    Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001891phagocytic cup ISS--
    GO:0005615extracellular space IDA18355445
    GO:0005622intracellular ----
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane IDA18355445


    TNF for ontologies           About GeneDecksing



    TNF Antibody Products: 
    EMD Millipore Mono- and Polyclonal Antibodies for the study of TNF
    R&D Systems Antibodies for TNF (TNF-alpha/TNFSF1A)
    Cell Signaling Technology (CST) Antibodies for TNF  (TNF-a)
    OriGene Antibodies (see all 5): TNF
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    Novus Biologicals TNF Antibodies
    Abcam antibodies for TNF 
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    Assay Products for TNF: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for TNF
    Cell Signaling Technology (CST) Sandwich ELISA Kits for TNF (TNF-a)
    Enzo Life Sciences assays for TNF
    Browse ELISAs and CLIAs at Uscn


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TNF for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR002959 TNF_alpha
     IPR006052 TNF
     IPR006053 TNF_a/b/c
     IPR008983 Tumour_necrosis_fac-like_dom
     IPR021184 TNF_CS

    Graphical View of Domain Structure for InterPro Entry P01375

    ProtoNet protein and cluster: P01375

    3 Blocks protein families:
    IPB002959 Tumour necrosis factor alpha (cachectin) signature
    IPB006052 Tumor Necrosis Factor
    IPB006053 Tumour necrosis factor family signature


    UniProtKB/Swiss-Prot: TNFA_HUMAN, P01375
    Similarity: Belongs to the tumor necrosis factor family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: TNFA_HUMAN, P01375
    Function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce
    cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of
    interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell
    proliferation and induce cell differentiation
    Function: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells

         Genatlas biochemistry entry for TNF:
    tumor necrosis factor,alpha (cachectin),potent proinflammatory cytokine,involved in inflammatory and immune
    responses,stimulating the sphingomyelinase (SMPD1),enhancing insulin resistance in peripheral tissues of cancer
    patients,susceptibility factor for narcolepsy and myasthenia gravis and cardiac sarcoidosis,with a common polymorphism
    in the promoter region (C->A) associated with reduced circulating levels of TNF,mediating neuronal death in injured
    brain (by inducing resistance to the protective effect of IGF1)

         Summary:  
    During embryonic development, TNF as signaling molecule
    affects the following cells: Fetal Hepatocytes in Liver Lobule

    TNF as growth factor is involved in stem cell differentiation protocols towards the derivation of the following cells: Dendritic-like cells, Mature dendritic-like cells

    miRNA
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    OriGene 3'-UTR Clone: TNF
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TNF
    8/29 QIAGEN miScript miRNA Assays for microRNAs that regulate TNF (see all 29):
    hsa-miR-549 hsa-miR-875-3p hsa-miR-181c hsa-miR-3141 hsa-miR-4263 hsa-miR-331-3p hsa-miR-301a hsa-miR-181a-2*
    SwitchGear 3'UTR luciferase reporter plasmidTNF 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TNF (see all 7)
    OriGene shRNA RFP: TNF
    OriGene siRNA: TNF
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TNF

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TNF

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TNF (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TNF
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TNF (NM_001192)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TNF 

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNF

    Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002020protease binding IPI12777399
    GO:0005125cytokine activity IDA10748004
    GO:0005164tumor necrosis factor receptor binding IDA14512626
    GO:0005515protein binding IPI--
    GO:0042802identical protein binding IDA14512626


    TNF for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for TNF:
     Increased cell death in breast 

    Animal Models:
         Mouse knock-outs for TNF: Ltb/TnfLtb/tm1.1Dvk Lta/TnfLta/tm1Eug Tnftm1Jods Lta/TnfLta/tm1Fda Tnftm1Sek Tnftm1Gkl
                                                   Tnftm3Gkl Ltb/Tnf/LtaLtb/Tnf/tm1Dvk Tnftm2.1Gkl Tnftm1Ljo Tnftm1.2Sned Lta/TnfLta/tm1Jods Tnftm2Gkl
         15/24 MGI mutant phenotypes (inferred from 19 alleles(MGI details for Tnf) (see all 24):
     adipose tissue  behavior/neurological  cardiovascular system  cellular  craniofacial 
     digestive/alimentary  embryogenesis  endocrine/exocrine gland  growth/size  hematopoietic system 
     homeostasis/metabolism  immune system  integument  limbs/digits/tail  liver/biliary system 

    TNF for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/90 super-pathways (see all 90About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1PEDF Induced Signaling
    8/9 pathways (see all 9)
    PEDF Induced Signaling1.00
    RAR-Gamma-RXR-Alpha Degradation0.54
    MIF Mediated Glucocorticoid Regulation0.73
    STAT3 Pathway0.47
    MIF Regulation of Innate Immune Cells0.71
    Endothelin-1 Signaling Pathway0.44
    IL-6 Pathway0.61
    Cytokine-cytokine receptor interaction0.26
    2TWEAK Pathway
    TNFR1 Pathway0.53
    TNF Signaling0.40
    HIV-1 Nef- Negative effector of Fas and TNF-alpha0.42
    Apoptotic Pathways Triggered By HIV10.37
    Apoptosis and survival_TNFR1 signaling pathway0.40
    Apoptosis through Death Receptors0.32
    Apoptosis and survival TNFR1 signaling pathway0.40
    TWEAK Signaling Pathway0.31
    3Allograft rejection
    Allograft rejection1.00
    Asthma0.44
    Type I diabetes mellitus0.67
    THC Differentiation Pathway0.39
    Graft-versus-host disease0.63
    Antigen processing and presentation0.25
    4Rho Family GTPases
    Rho Family GTPases1.00
    MAPK Signaling0.51
    ERK Signaling0.61
    ILK Signaling0.45
    Molecular Mechanisms of Cancer0.51
    5Apoptosis and survival_Caspase cascade
    Apoptosis and survival_Caspase cascade1.00
    Caspase cascade in apoptosis0.42
    Apoptosis and survival Caspase cascade1.00
    FAS pathway and Stress induction of HSP regulation0.33

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    5/14 EMD Millipore Pathways for TNF (see all 14)
        Immune response CD16 signaling in NK cells
    Immune response IL-9 signaling pathway
    Immune response MIF-mediated glucocorticoid regulation
    Immune response MIF in innate immunity response
    Immune response IL-1 signaling pathway

    5/7 R&D Systems Pathways for TNF (see all 7)
        TNF Superfamily - Human Ligand-Receptor Interactions & their Associated Functions
    Adipocytokines & Insulin Signaling
    Th1 Differentiation
    Toll-Like receptor Signaling Pathways
    Apoptosis Signaling Pathways

    5/50 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for TNF (see all 50)
        Caspase Cascade
    THC Differentiation Pathway
    14-3-3 Induced Apoptosis
    Molecular Mechanisms of Cancer
    Antioxidant Action of Vitamin-C

    2 Cell Signaling Technology (CST) Pathways for TNF
        Apoptosis and Autophagy
    NF-kappaB Signaling

    5/15 GeneGo (Thomson Reuters) Pathways for TNF (see all 15)
        Apoptosis and survival Anti-apoptotic TNFs/NF-kB/IAP pathway
    Immune response MIF-mediated glucocorticoid regulation
    Apoptosis and survival Caspase cascade
    Immune response MIF in innate immunity response
    Immune response IL-9 signaling pathway

    5/34 BioSystems Pathways for TNF (see all 34
        MicroRNAs in cardiomyocyte hypertrophy
    Notch Signaling Pathway
    Matrix Metalloproteinases
    Adipogenesis
    EBV LMP1 signaling

    4        Reactome Pathways for TNF
        Death Receptor Signalling
    TNF signaling
    Extrinsic Pathway for Apoptosis
    Apoptosis


    5/35         Kegg Pathways  (Kegg details for TNF) (see all 35):
        MAPK signaling pathway
    Cytokine-cytokine receptor interaction
    Apoptosis
    TGF-beta signaling pathway
    Osteoclast differentiation


    TNF for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TNF

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    5/108 Interacting proteins for TNF (P013751, 2, 3 ENSP000003986984) via UniProtKB, MINT, STRING, and/or I2D (see all 108)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IKBKGQ9Y6K92, 3MINT-8410390 I2D: score=1 
    RBCK1Q9BYM82, 3MINT-8410390 I2D: score=1 
    RNF31Q96EP02, 3MINT-8410390 I2D: score=1 
    TNFAIP3P215802, 3MINT-8410390 I2D: score=1 
    TNFRSF1AP194381, 2, 3, ENSP000001627494EBI-359977,EBI-299451 MINT-48045 MINT-49295 I2D: score=12 STRING: ENSP00000162749
    About this table

    Gene Ontology (GO): 5/119 biological process terms (GO ID links to tree view) (see all 119):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000060protein import into nucleus, translocation IDA16280327
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IDA15345745
    GO:0000165MAPK cascade IMP--
    GO:0000185activation of MAPKKK activity IDA15310755
    GO:0000187activation of MAPK activity IDA10748004


    TNF for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TNF for compounds           About GeneDecksing

    EMD Millipore small molecules for TNF:
    Small Molecule - inhibitor
    Enzo Life Sciences drugs & compounds for TNF

    Compounds for TNF available from Tocris Bioscience    About this table
    CompoundAction CAS #
    PiceatannolInhibits TNF-induced NF-kappaB activation[10083-24-6]
    Bay 11-7821Irreversible inhibitor of TNF-alpha-induced IkappaBalpha phosphorylation[19542-67-7]
    ThalidomideTNF-alpha synthesis inhibitor[50-35-1]
    Bay 11-7085Irreversible inhibitor of TNF-alpha-induced IkappaBalpha phosphorylation[196309-76-9]

    4 HMDB Compounds for TNF    About this table
    CompoundSynonyms CAS #PubMed Ids
    Butyric acid1-Butyrate (see all 25)107-92-616142751
    AtorvastatinAtorvastatin acid (see all 4)134523-00-5--
    Glucosamine2-Amino-2-deoxy-D-glucopyranose (see all 10)3416-24-8--
    Simvastatin(+)-Simvastatin (see all 28)79902-63-9--

    9 DrugBank Compounds for TNF    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Infliximab-- 170277-31-3targetinhibitor15691299 16622728 11752352 15691217 12110154 17642244 15481318 16052578 16456024 15674127 15804598
    Adalimumab-- 331731-18-1targetantibody11752352 15200343 12044041 14532145 15022409 15046527
    EtanerceptCD120b (see all 7)185243-69-0targetantibody10375846 10206649 10405518 10338381 11752352 10357816
    Thalidomidealpha-phthalimidoglutarimide (see all 5)50-35-1targetinhibitor12167383 12105857 12046682 12113124 11752352 12102294
    AmrinoneAmrinona [inn-spanish] (see all 4)60719-84-8targetinhibitor1611705 10444479 10075051 11805217 11969359
    ChloroquineChloraquine (see all 6)54-05-7target--16418198 16761500 17456179 16870179 16670522
    Clenbuterol-- 37148-27-9targetother/unknown10071758 15021963 17139543 16261833 11193379
    Glucosamine-- 3416-24-8target--16431966 16469053 16445576 12244074 15930455
    Pranlukast-- 103177-37-3targetother/unknown17430359 12801315 12801316

    10/141 Novoseek chemical compound relationships for TNF gene (see all 141)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    infliximab 92.6 1681 16095114 (7), 11961039 (7), 12632433 (7), 15538942 (6) (see all 99)
    etanercept 92 1158 11961039 (8), 19188093 (5), 15005015 (5), 20443835 (5) (see all 99)
    adalimumab 89.5 487 11730333 (10), 19188093 (4), 17343250 (3), 17502862 (3) (see all 99)
    endotoxin 87.3 2305 8687293 (8), 1643887 (7), 9185243 (7), 1770269 (7) (see all 99)
    rantes 83.7 975 16466762 (6), 12663241 (6), 9527395 (6), 12388374 (5) (see all 99)
    pge2 79.9 2340 9298541 (9), 8388910 (8), 1836009 (8), 2378446 (7) (see all 99)
    il 10 79.5 347 19771178 (7), 11166831 (5), 15800006 (5), 12719394 (5) (see all 99)
    pentoxifylline 78.4 990 8189599 (9), 1385797 (8), 7589090 (7), 9486396 (6) (see all 99)
    nitric oxide 76.3 4152 7706743 (11), 8046239 (9), 11566624 (9), 1517576 (8) (see all 99)
    abatacept 74.2 77 19916731 (4), 18590608 (4), 17057043 (3), 18670735 (3) (see all 42)

    5 PharmGKB related drug/compound annotations for TNF gene
    Drug/compound PharmGKB Annotation
    abacavirCA  
    adalimumabCA  
    carbamazepineCA  
    etanerceptCA  
    infliximabCA  
    About this table

    Search CenterWatch for drugs/clinical trials and news about TNF / TNFA 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TNF gene: 
    NM_000594.3  

    Unigene Cluster for TNF:

    Tumor necrosis factor
    Hs.241570  [show with all ESTs]
    Unigene Representative Sequence: NM_000594
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000449264(uc003nui.3 uc003nuj.3)

    miRNA
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    OriGene 3'-UTR Clone: TNF
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TNF
    8/29 QIAGEN miScript miRNA Assays for microRNAs that regulate TNF (see all 29):
    hsa-miR-549 hsa-miR-875-3p hsa-miR-181c hsa-miR-3141 hsa-miR-4263 hsa-miR-331-3p hsa-miR-301a hsa-miR-181a-2*
    SwitchGear 3'UTR luciferase reporter plasmidTNF 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TNF (see all 7)
    OriGene shRNA RFP: TNF
    OriGene siRNA: TNF
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TNF
    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TNF (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TNF
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TNF (NM_001192)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TNF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TNF 
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TNF
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TNF

    Additional cDNA sequence: 

    AB451492.1 AF043342.1 AF098751.1 AJ227911.1 AK314960.1 BC028148.1 FJ795028.1 HQ201306.2 
    M10988.1 X01394.1 

    6 DOTS entries:

    DT.447264  DT.75172441  DT.100717788  DT.121394302  DT.40132506  DT.95165288 

    24/68 AceView cDNA sequences (see all 68):

    X01394 BM762686 BC028148 BM844832 CD364761 BM842415 CA307225 BG232086 
    CA310368 NM_000594 BM831593 CD368116 M10988 CA309664 CD368142 BI907528 
    AA381586 CD366187 BM844831 AJ227911 AI242177 BI910312 CA308256 BI908079 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TNF expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TAGCCCCCTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    TNF expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Early Embryo (Zygote)Morula8-Cell EmbryoEarly Embryo
    LiverSinusoidsKupffer CellsBlood
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See TNF Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TNF

    SOURCE GeneReport for Unigene cluster: Hs.241570
        SABiosciences Expression via Pathway-Focused PCR Arrays including TNF (see all 50): 
              Lung Cancer in human mouse rat
              Antiviral Response in human mouse rat
              Multiple Sclerosis in human mouse rat
              Wound Healing in human mouse rat
              Lymphoma in human mouse rat

    Primer
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    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TNF
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TNF
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TNF

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for TNF gene from 2/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia TNF6
    --
    36(a)
    1 ↔ 1
    2(195687375-195691887)
    zebrafish
    (Danio rerio)
    Actinopterygii tnfa6
    tnfb6
    tumor necrosis factor a (TNF superfamily, member 2...
    tumor necrosis factor b (TNF superfamily, member 2...
    26(a)
    21(a)
    many ↔ many
    many ↔ many
    19(27505097-27509684)
    15(33995840-33998916)


    ENSEMBL Gene Tree for TNF (if available)
    TreeFam Gene Tree for TNF (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TNF gene
    FASLG2  TNFSF152  LTA2  TNFSF142  
    2 SIMAP similar genes for TNF using alignment to 5 protein entries:     TNFA_HUMAN (see all proteins):
    LTA    FASLG

    TNF for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    UniProtKB/Swiss-Prot: TNFA_HUMAN, P01375
    Polymorphism: Genetic variations in TNF influence susceptibility to hepatitis B virus (HBV) infection [MIM:610424]
    Polymorphism: Genetic variations in TNF are involved in susceptibility to malaria [MIM:611162]


    10/93 NCBI SNPs in TNF are shown (see all 93    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs27361961,2
    C,H--31329389(-) ATGCTG/TGTTTC 1 -- us2k14Minor allele frequency- T:0.00NS EA 406
    rs27361951,2
    C--31329425(-) AGGCCC/TTCTTC 1 -- us2k10--------
    rs42481601,2
    C,F,--31329427(+) AGAAGG/ACCTGC 1 -- us2k13Minor allele frequency- A:0.01NS NA 332
    rs42481621,2
    C,F--31329503(+) GCTACC/ACCCAC 1 -- us2k12Minor allele frequency- A:0.01NS 330
    rs28577111,2
    C--31329505(-) GGGTGC/GGGGTA 1 -- us2k10--------
    rs30935481,2
    C--31329554(+) AGCTCC/TTTCTC 1 -- us2k12Minor allele frequency- T:0.01NS 94
    rs42481631,2
    C,F--31329562(+) CTCCCC/GGCAGG 1 -- us2k12Minor allele frequency- G:0.01NS 328
    rs18007501,2
    C,F,H,--31329697(+) TGGAAG/ATTAGA 1 -- us2k127Minor allele frequency- A:0.02NS MN EA NA 3174
    rs49870271,2
    C,--31329828(+) CCCCTA/C/TRGAAT 1 -- us2k15MN 400
    rs6731,2
    C,F,--31329829(+) CCCTCG/AGAATC 1 -- us2k120Minor allele frequency- A:0.35NS MN NA WA 1862

    HapMap Linkage Disequilibrium report for TNF (31543344 - 31546113 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TNF: --
    Human Gene Mutation Database (HGMD): TNF

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TNF
    DNA2.0 Custom Variant and Variant Library Synthesis for TNF

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TNF for disorders           About GeneDecksing

    OMIM gene information: 191160   
    OMIM disorders: 611162  600807  157300  
    UniProtKB/Swiss-Prot: TNFA_HUMAN, P01375
  • Genetic variations in TNF are a cause of susceptibility psoriatic arthritis (PSORAS) [MIM:607507]. PSORAS is
  • an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild,
    non-destructive disease to a severe, progressive, erosive arthropathy. Five types of psoriatic arthritis have been
    defined: asymmetrical oligoarthritis characterized by primary involvement of the small joints of the fingers or toes;
    asymmetrical arthritis which involves the joints of the extremities; symmetrical polyarthritis characterized by a
    rheumatoidlike pattern that can involve hands, wrists, ankles, and feet; arthritis mutilans, which is a rare but
    deforming and destructive condition; arthritis of the sacroiliac joints and spine (psoriatic spondylitis)

    20/783 diseases for TNF (see all 783):    About MalaCards
    charcot-marie-tooth neuropathy    charcot-marie-tooth neuropathy type 2    new daily-persistent headache    charcot-marie-tooth neuropathy type 2a
    periodic fever, aphthous stomatitis, pharyngitis and adenitis    punctate inner choroidopathy    insulin resistance    carotid intimal medial thickness
    migraine without aura    crimean-congo hemorrhagic fever    open-angle glaucoma    lambert-eaton myasthenic syndrome
    post-transplant lymphoproliferative disease    graft versus host disease    monoclonal gammopathy of uncertain significance    maternally inherited leigh syndrome
    perinatal necrotizing enterocolitis    alpha 1-antitrypsin deficiency    benign migratory glossitis    weill-marchesani syndrome

    14 diseases from the University of Copenhagen DISEASES database for TNF:
    Rheumatoid arthritis     Inflammatory bowel disease     Hypersensitivity reaction type II disease     Cancer
    Malaria     Connective tissue disease     Ankylosing spondylitis     Psoriatic arthritis
    Psoriasis     Tuberculosis     Vascular disease     Multiple sclerosis
    Asthma     Peritonitis

    10/96 Novoseek disease relationships for TNF gene (see all 96)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    necrosis 99 80542 15626980 (12), 1595815 (11), 2374209 (11), 10561634 (10) (see all 99)
    tumors 96.4 68579 15626980 (12), 1595815 (11), 2374209 (11), 10561634 (10) (see all 99)
    inflammation 92.2 3272 17482668 (5), 20439544 (5), 7737534 (4), 9042105 (4) (see all 99)
    rheumatoid arthritis 90.1 2641 1802490 (5), 15879156 (4), 8329189 (4), 19560810 (4) (see all 99)
    arthritis psoriatic 79 279 16284098 (4), 9326391 (4), 15838232 (3), 14678719 (3) (see all 99)
    sepsis 78.9 1166 1860332 (7), 15526005 (6), 2064171 (5), 8403981 (5) (see all 99)
    tumor necrosis factor receptor-associated periodic syndrome 78.8 119 12352631 (2), 15689926 (2), 18347298 (2), 15492850 (2) (see all 82)
    spondylitis ankylosing 77.7 312 9704649 (4), 15838232 (3), 17414952 (3), 16763453 (3) (see all 99)
    shock septic 77.7 621 9366763 (8), 2285204 (5), 8318801 (5), 10966243 (4) (see all 99)
    arthritis 77.5 684 8033415 (5), 9585810 (5), 7589090 (5), 8222316 (4) (see all 99)

    Genetic Association Database (GAD): TNF
    Human Genome Epidemiology (HuGE) Navigator: TNF (2475 documents)
    Tumor Gene Database (TGDB): TNF

    Export disorders for TNF gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TNF gene, integrated from 9 sources (see all 16820) (see top 10):
    (articles sorted by number of sources associating them with TNF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria. (PubMed id 10369255)1, 2, 4, 9 Knight J.C....Kwiatkowski D. (1999)
    2. Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. (PubMed id 6392892)1, 2, 3 Pennica D.... Goeddel D.V. (1984)
    3. TNF-alpha promoter, Nod2 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin. (PubMed id 15016407)1, 4, 9 Schippers E.F....van Dissel J.T. (2004)
    4. TNF and TNFR polymorphisms in severe sepsis and septic shock: a prospective multicentre study. (PubMed id 15526005)1, 4, 9 Gordon A.C....Hinds C.J. (2004)
    5. Relation of tumor necrosis factor (TNF) gene polymorphisms with serum concentrations and in vitro production of TNF-alpha and interleukin-8 in heavy drinkers. (PubMed id 15902922)1, 4, 9 Gonzalez-Quintela A....Perez L.F. (2004)
    6. Genetic variation in the stress protein hsp70-2 gene is highly associated with obesity. (PubMed id 11319647)1, 4, 9 Chouchane L....Strosberg A.D. (2001)
    7. Polymorphism of cytokine genes (TGF-beta1, IFN-gamma, IL-6, IL-10, and TNF-alpha) in patients with chronic pancreatitis. (PubMed id 15841043)1, 4, 9 Bendicho M.T....Lemaire D.C. (2005)
    8. -238 and +489 TNF-alpha along with TNF-RII gene polymorphisms associate with the diffuse phenotype in patients with Systemic Sclerosis. (PubMed id 15585313)1, 4, 9 Tolusso B....Ferraccioli G. (2005)
    9. [The associations of the single nucleotide polymorphisms on TNF and CD14 promoters with the mortality of infection, systematic inflammatory response syndromec and sepsis in surgical patients] (PubMed id 14720421)1, 4, 9 Yu B.J....Tang X.M. (2003)
    10. Polymorphisms in the +252(A/G) lymphotoxin-alpha and the -308(A/G) tumor necrosis factor-alpha genes and susceptibility to chronic periodontitis in a Czech population. (PubMed id 12828656)1, 4, 9 Fassmann A....Vanek J. (2003)
    11. MHC class II, tumour necrosis factor alpha, and lymphotoxin alpha gene haplotype associations with serological subsets of systemic lupus erythematosus. (PubMed id 16107511)1, 4, 9 McHugh N.J....Welsh K. (2006)
    12. Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph Consortium. (PubMed id 16389181)1, 4, 9 Rothman N....Nieters A. (2006)
    13. Association between TNF-alpha and TGF-beta genotypes in infants and parental history of allergic rhinitis and asthma. (PubMed id 15120189)1, 4, 9 Gentile D.A....Skoner D.P. (2004)
    14. [Potential effect of tumor necrosis factor-alpha and tumor necrosis factor receptor II gene polymorphisms on the pathogenesis of silicosis.] (PubMed id 15555301)1, 4, 9 Li L....Liu B.C. (2004)
    15. Polymorphisms in the tumor necrosis factor-alpha gene at position -308 and the inducible 70 kd heat shock protein gene at position +1267 in multifetal pregnancies and preterm premature rupture of fetal membranes. (PubMed id 15507967)1, 4, 9 Kalish R.B....Witkin S.S. (2004)
    16. [Potential effect of tumor necrosis factor-alpha and its receptor II gene polymorphisms on the pathogenesis of coal worker's pneumoconiosis] (PubMed id 15355698)1, 4, 9 Li L....Wang H.L. (2004)
    17. Relation between tumour necrosis factor polymorphism TNFalpha-308 and risk of asthma. (PubMed id 11896460)1, 4, 9 Witte J.S....Hall J.M. (2002)
    18. Interleukin-6 and interferon-gamma gene polymorphisms in the development of bronchiolitis obliterans syndrome after lung transplantation. (PubMed id 12451269)1, 4, 9 Lu K.C....Mohanakumar T. (2002)
    19. The G-->A single nucleotide polymorphism at the -308 position in the tumor necrosis factor-alpha promoter increases the risk for severe sepsis after trauma. (PubMed id 11988644)1, 4, 9 O'Keefe G.E....Munford R.S. (2002)
    20. Promoter polymorphisms of the genes encoding tumor necrosis factor-alpha and interleukin-1beta are associated with different subtypes of psoriasis characterized by early and late disease onset. (PubMed id 11851889)1, 4, 9 Reich K....Neumann C. (2002)
    21. Interleukin-10 and tumor necrosis factor gene polymorphisms and risk of coronary artery disease and myocardial infarction. (PubMed id 11689215)1, 4, 9 Koch W....Schomig A. (2001)
    22. Cytokine gene polymorphisms in psoriasis. (PubMed id 11298547)1, 4, 9 Craven N.M....Griffiths C.E. (2001)
    23. Tumor necrosis factor, tumor necrosis factor receptors type 1 and 2, lymphotoxin-alpha, and HLA-DRB1 gene polymorphisms in human T-cell lymphotropic virus type I associated myelopathy. (PubMed id 11163081)1, 4, 9 Nishimura M....Uchiyama T. (2000)
    24. Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study. (PubMed id 10450718)1, 4, 9 Mira J.P....Dhainaut J.F. (1999)
    25. Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria. (PubMed id 7935762)1, 4, 9 McGuire W....Kwiatkowski D. (1994)
    26. Interaction of the -308G/A promoter polymorphism of the tumor necrosis factor-alpha gene with single-nucleotide polymorphism 45 of the adiponectin gene: effect on serum adiponectin concentrations in a Spanish population. (PubMed id 16254197)1, 4, 9 Gonzalez-Sanchez J.L....Serrano-Rios M. (2006)
    27. Polymorphism of the TNF-alpha, HSP70-2, and CD14 genes increases susceptibility to severe acute pancreatitis. (PubMed id 15714129)1, 4, 9 Balog A....Mandi Y. (2005)
    28. Influence of cytokine and ICAM-1 gene polymorphisms on susceptibility to chronic pancreatitis. (PubMed id 15917409)1, 4, 9 Howell W.M....Bateman A.C. (2005)
    29. Heat shock protein 70 and tumor necrosis factor alpha in Taiwanese patients with dementia. (PubMed id 15832029)1, 4, 9 Fung H.C....Lee-Chen G.J. (2005)
    30. Influence of toll-like receptor 4, CD14, tumor necrosis factor, and interleukine-10 gene polymorphisms on clinical outcome in Japanese critically ill patients. (PubMed id 16051275)1, 4, 9 Nakada T.A....Tokuhisa T. (2005)
    31. Are genetic polymorphisms of tumour necrosis factor alpha, interleukin-10, CD14 endotoxin receptor or manganese superoxide dismutase associated with alcoholic liver disease? (PubMed id 16148556)1, 4, 9 Martins A....Camilo M.E. (2005)
    32. Lack of a strong association between HLA class II, tumour necrosis factor and transporter associated with antigen processing gene polymorphisms and virological response to alpha-interferon treatment in patients with chronic hepatitis C. (PubMed id 15548263)1, 4, 9 Airoldi A....Pinzello G. (2004)
    33. Genetic polymorphisms in tumor necrosis factor (TNF)-alpha and TNF-beta in a population-based study of systemic lupus erythematosus: associations and interaction with the interleukin-1alpha-889 C/T polymorphism. (PubMed id 15219382)1, 4, 9 Parks C.G....Cooper G.S. (2004)
    34. Innate immunity genes influence the severity of acute appendicitis. (PubMed id 15273551)1, 4, 9 Rivera-Chavez F.A....O'Keefe G.E. (2004)
    35. Polymorphism of stress protein HSP70-2 gene in Tunisians: susceptibility implications in type 2 diabetes and obesity. (PubMed id 15223990)1, 4, 9 Zouari Bouassida K....Danguir J. (2004)
    36. [Allelic variants of the tumor necrosis factor superfamily as markers of the severity of the course of chronic obstructive lung disease and bronchiectatic disease] (PubMed id 15174288)1, 4, 9 Ianbaeva D.G....Viktorova T.V. (2004)
    37. A study of candidate genes for psoriasis near HLA-C in Chinese patients with psoriasis. (PubMed id 12653732)1, 4, 9 Chang Y.T....Wong C.K. (2003)
    38. The effect of the -308A allele of the TNF-alpha gene on insulin action is dependent on obesity. (PubMed id 12855762)1, 4, 9 Pihlajamaki J....Laakso M. (2003)
    39. Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors. (PubMed id 12019209)1, 4, 9 van Heel D.A....Kwiatkowski D. (2002)
    40. Polymorphisms in candidate obesity genes and their interaction with dietary intake of n-6 polyunsaturated fatty acids affect obesity risk in a sub-sample of the EPIC-Heidelberg cohort. (PubMed id 12395215)1, 4, 9 Nieters A....Linseisen J. (2002)
    41. Bone mineral mass is associated with interleukin 1 receptor autoantigen and TNF-alpha gene polymorphisms in post-menopausal Mediterranean women. (PubMed id 12240899)1, 4, 9 Fontova R....Richart C. (2002)
    42. Analysis of tumor necrosis factor-alpha, lymphotoxin-alpha, tumor necrosis factor receptor II, and interleukin-6 polymorphisms in patients with idiopathic pulmonary fibrosis. (PubMed id 11371414)1, 4, 9 Pantelidis P....Du Bois R.M. (2001)
    43. Association of tumor necrosis factor alpha gene promoter polymorphism with the presence of chronic obstructive pulmonary disease. (PubMed id 11179116)1, 4, 9 Sakao S....Kuriyama T. (2001)
    44. Lack of association between adult asthma and the tumour necrosis factor alpha-308 polymorphism gene. (PubMed id 11106199)1, 4, 9 Louis R....Louis E. (2000)
    45. Distinct tumour necrosis factor alpha, interferon gamma, interleukin 10, and cytotoxic T cell antigen 4 gene polymorphisms in disease occurrence and end stage renal disease in Wegener's granulomatosis. (PubMed id 15708894)1, 4, 9 Spriewald B.M....Kalden J.R. (2005)
    46. Association of the -159 CD14 gene polymorphism and lack of association of the -308 TNFA and Q551R IL-4RA polymorphisms with severe chronic periodontitis in Swedish Caucasians. (PubMed id 15842262)1, 4, 9 Donati M....Padyukov L. (2005)
    47. Association of gene polymorphisms of tumour necrosis factor-alpha and interleukin-13 with chronic obstructive pulmonary disease in Han nationality in Beijing. (PubMed id 15820084)1, 4, 9 Jiang L....Yao W.Z. (2005)
    48. CD14 receptor polymorphism and Alzheimer's disease risk. (PubMed id 15854776)1, 4, 9 Combarros O....Berciano J. (2005)
    49. [Recognition and study of susceptible gene to ankylosing spondylitis] (PubMed id 15730950)1, 4, 9 Zhu X.Q....Yang Z. (2005)
    50. 1267 HSP70-2 polymorphism as a risk factor for carotid plaque rupture and cerebral ischaemia in old type 2 diabetes-atherosclerotic patients. (PubMed id 15992611)1, 4, 9 Giacconi R....Mocchegiani E. (2005)
    51. [Genetic association of tumor necrosis factor (TNF)-alpha polymorphisms with primary biliary cirrhosis and autoimmune liver diseases in a Chinese population] (PubMed id 15059302)1, 4, 9 Fan L.Y....Zhou L. (2004)
    52. [Polymorphism of TNF-alpha in autoimmunity and tuberculosis] (PubMed id 15495570)1, 4, 9 Correa P.A....Anaya J.M. (2004)
    53. Genetic risk factors for infection in patients with early rheumatoid arthritis. (PubMed id 15526004)1, 4, 9 Hughes L.B....Bridges S.L. (2004)
    54. Genetic contribution of tumor necrosis factor (TNF)-alpha gene promoter (-1031, -863 and -857) and TNF receptor 2 gene polymorphisms in endometriosis susceptibility. (PubMed id 15212671)1, 4, 9 Teramoto M....Honjo H. (2004)
    55. Genetic association of cutaneous neonatal lupus with HLA class II and tumor necrosis factor alpha: implications for pathogenesis. (PubMed id 15334474)1, 4, 9 Clancy R.M....Buyon J.P. (2004)
    56. [Tumor necrosis factor-alpha and interleukin-10 gene polymorphisms in Korean patients with inflammatory bowel disease] (PubMed id 14646574)1, 4, 9 Kim T.H....Song I.S. (2003)
    57. Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen. (PubMed id 12871600)1, 4, 9 Adams G.T....Kutlar A. (2003)
    58. Relationship between the tumor necrosis factor alpha polymorphism and the serum C-reactive protein levels in inflammatory bowel disease. (PubMed id 12811429)1, 4, 9 Vatay A....Fust G. (2003)
    59. Effect of TNF and LTA polymorphisms on biological markers of response to oxidative stimuli in coal miners: a model of gene-environment interaction. Tumour necrosis factor and lymphotoxin alpha. (PubMed id 12566517)1, 4, 9 Nadif R....Kauffmann F. (2003)
    60. A tumor necrosis factor-alpha-inducible promoter variant of interferon-gamma accelerates CD4+ T cell depletion in human immunodeficiency virus-1-infected individuals. (PubMed id 12854077)1, 4, 9 An P....Winkler C.A. (2003)
    61. Analysis of the modifying effects of SAA1, SAA2 and TNF-alpha gene polymorphisms on development of amyloidosis in FMF patients. (PubMed id 14696796)1, 4, 9 Yilmaz E....Bakkaloglu A. (2003)
    62. Tumor necrosis factor-alpha promoter gene polymorphism -308 and chorioamnionitis. (PubMed id 12850624)1, 4, 9 Simhan H.N....Caritis S.N. (2003)
    63. Association between novel GM-CSF gene polymorphisms and the frequency and severity of atopic dermatitis. (PubMed id 13679820)1, 4, 9 Rafatpanah H....Arkwright P.D. (2003)
    64. Association of IL2, TNFA, IL4 and IL10 Promoter Gene Polymorphisms with the Rate of Progression of the HIV Infection. (PubMed id 12687247)1, 4, 9 Smolnikova M.V. and Konenkov V.I. (2002)
    65. Host defense and inflammatory gene polymorphisms are associated with outcomes after HLA-identical sibling bone marrow transplantation. (PubMed id 12393699)1, 4, 9 Rocha V....Gluckman E. (2002)
    66. Association of the TNF-alpha -308 G/A promoter polymorphism with insulin resistance in obesity. (PubMed id 12006640)1, 4, 9 Dalziel B....Caterson I.D. (2002)
    67. Association of a single nucleotide variant in the human tumour necrosis factor alpha promoter region with decreased bone mineral density. (PubMed id 12396374)1, 4, 9 Ota N....Emi M. (2002)
    68. Cytokine gene polymorphisms in children successfully withdrawn from immunosuppression after liver transplantation. (PubMed id 11981433)1, 4, 9 Mazariegos G.V....Zeevi A. (2002)
    69. Profound bias in interferon-gamma and interleukin-6 allele frequencies in western Kenya, where severe malarial anemia is common in children. (PubMed id 12232842)1, 4, 9 Gourley I.S....Duffy P.E. (2002)
    70. Lack of association between atopic asthma and the tumor necrosis factor alpha-308 gene polymorphism in a Czech population. (PubMed id 12530118)1, 4, 9 Buckova D....Vacha J. (2002)
    71. Polymorphisms in the TNF-alpha and TNF-receptor genes in patients with coronary artery disease. (PubMed id 11737221)1, 4, 9 Allen R.A....Pirmohamed M. (2001)
    72. Septic shock and respiratory failure in community-acquired pneumonia have different TNF polymorphism associations. (PubMed id 11401880)1, 4, 9 Waterer G.W....Wunderink R.G. (2001)
    73. Association between -G308A tumor necrosis factor alpha gene polymorphism and schizophrenia. (PubMed id 11244489)1, 4, 9 Boin F....Gennarelli M. (2001)
    74. TNFalpha promoter region gene polymorphisms in carbamazepine-hypersensitive patients. (PubMed id 11294926)1, 4, 9 Pirmohamed M....Park B.K. (2001)
    75. Lack of association between promoter polymorphism of the tumor necrosis factor-alpha gene and psoriatic arthritis in Japanese patients. (PubMed id 11121160)1, 4, 9 Hamamoto Y....Muto M. (2000)
    76. Tumor necrosis factor gene polymorphisms in patients with cirrhosis from chronic hepatitis C virus infection. (PubMed id 11196686)1, 4, 9 Yee L.J....van Leeuwen D.J. (2000)
    77. Association of genotypes affecting the expression of interleukin-1beta or interleukin-1 receptor antagonist with osteoarthritis. (PubMed id 11083263)1, 4, 9 Moos V....Muller B. (2000)
    78. Interaction analysis between 5-HTTLPR and TNFA -238/-308 polymorphisms in schizophrenia. (PubMed id 16252073)1, 4 Pae C.U....Lee C. (2006)
    79. Cytokine gene polymorphisms in Colombian patients with different clinical presentations of tuberculosis. (PubMed id 15925543)1, 4 Henao M.I....Garcia L.F. (2006)
    80. Genetic and environmental factors associated with the development of hypertension in pregnancy. (PubMed id 16369102)1, 4 Kobashi G. (2006)
    81. Type 1 diabetes in the Spanish population: additional factors to class II HLA-DR3 and -DR4. (PubMed id 15842729)1, 4 Urcelay E....de la Concha E.G. (2005)
    82. [Association of TNFA-308 gene polymorphisms with susceptibility to chronic periodontitis in Chinese patients] (PubMed id 16400484)1, 4 Pang R.Y....Zhang X. (2005)
    83. Genetic variations in IL6 associate with intervertebral disc disease characterized by sciatica. (PubMed id 15733644)1, 4 Noponen-Hietala N....Ala-Kokko L. (2005)
    84. Cytokine genotypes correlate with pain and radiologically defined joint damage in patients with juvenile rheumatoid arthritis. (PubMed id 15901906)1, 4 Oen K....Reed M. (2005)
    85. Lack of association between certain candidate gene polymorphisms and the metabolic syndrome. (PubMed id 15978856)1, 4 Meirhaeghe A....Dallongeville J. (2005)
    86. Association of CAT polymorphisms with catalase activity and exposure to environmental oxidative stimuli. (PubMed id 16298864)1, 4 Nadif R....Kauffmann F. (2005)
    87. Association of cytokine and DNA repair gene polymorphisms with hepatitis B-related hepatocellular carcinoma. (PubMed id 16172101)1, 4 Chen C.C....Yu M.W. (2005)
    88. Tumor necrosis factor alpha, CYP 17, urokinase, and interleukin 10 gene polymorphisms in postmenopausal women: correlation to bone mineral density and susceptibility to osteoporosis. (PubMed id 15927351)1, 4 Chen H.Y....Tsai C.H. (2005)
    89. Genetic predisposition for a compromised immune system after multiple trauma. (PubMed id 16317381)1, 4 Hildebrand F....Stuhrmann M. (2005)
    90. [Relationship between cytokine gene polymorphism and susceptibility to hepatitis B virus intrauterine infection] (PubMed id 15941525)1, 4 Zhu Q.R....Fei L.E. (2005)
    91. Tumor necrosis factor-alpha -308 promoter polymorphism contributes independently to HLA alleles in the severity of rheumatoid arthritis in Mexicans. (PubMed id 15725578)1, 4 Rodriguez-Carreon A.A....Vargas-Alarcon G. (2005)
    92. TNFalpha, IFNgamma and IL-10 gene polymorphisms in a sample of Sicilian patients with coeliac disease. (PubMed id 15979955)1, 4 Lio D....Cataldo F. (2005)
    93. Risks of human conotruncal heart defects associated with 32 single nucleotide polymorphisms of selected cardiovascular disease-related genes. (PubMed id 16100725)1, 4 Shaw G.M....Lammer E.J. (2005)
    94. IL-2 and TNF-alpha promoter polymorphisms in patients with acute kidney graft rejection. (PubMed id 15964333)1, 4 Pawlik A....Gawronska-Szklarz B. (2005)
    95. Genes and outcome after aneurysmal subarachnoid haemorrhage. (PubMed id 15726267)1, 4 Ruigrok Y.M....Wijmenga C. (2005)
    96. Cytokine gene polymorphisms in population of ethnic Macedonians. (PubMed id 16100774)1, 4 Trajkov D....Spiroski M. (2005)
    97. A role of TNF-alpha gene variant on juvenile ischemic stroke: a case-control study. (PubMed id 16324093)1, 4 Rubattu S....Rasura M. (2005)
    98. Genetic polymorphisms of interleukin (IL)-1B, IL-1RN, IL-8, IL-10 and tumor necrosis factor {alpha} and risk of gastric cancer in a Chinese population. (PubMed id 15579481)1, 4 Lu W....You W. (2005)
    99. CYP17 and tumor necrosis factor-alpha gene polymorphisms are associated with risk of oral cancer in Chinese patients in Taiwan. (PubMed id 15799583)1, 4 Chen W.C....Tsai F.J. (2005)
    100. Physical function and its response to exercise: associations with cytokine gene variation in older adults with knee osteoarthritis. (PubMed id 16282562)1, 4 Nicklas B.J....Pahor M. (2005)
    101. Associations between frequencies of a susceptible TNF-alpha promoter allele and protective alpha-thalassaemias and malaria parasite incidence in Vanuatu. (PubMed id 15941417)1, 4 Ubalee R....Hirayama K. (2005)
    102. [Genetic polymorphism of tumor necrosis factor-alpha in patients with chronic benzene poisoning] (PubMed id 16124898)1, 4 Lv L....Irons R.R. (2005)
    103. Association between tumour necrosis factor gene polymorphisms and the clinical types of patients with chronic hepatitis B virus infection. (PubMed id 15649304)1, 4 Xu X.W....Tan D.M. (2005)
    104. Polymorphisms in tumor necrosis factor genes and susceptibility to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma in a population of high incidence region of North China. (PubMed id 16313841)1, 4 Guo W....Zhang J.H. (2005)
    105. A polymorphism in the TNF-alpha promoter gene is associated with pediatric onset and colonic location of Crohn's disease. (PubMed id 15667501)1, 4 Levine A....Silver E.L. (2005)
    106. Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations. (PubMed id 15817713)1, 4 Hersh C.P....Silverman E.K. (2005)
    107. The relative importance of cytokine gene polymorphisms in the development of early and late acute rejection and six-month renal allograft pathology. (PubMed id 15818327)1, 4 Tinckam K....Nickerson P. (2005)
    108. Evaluation of cytokine polymorphisms (TNFalpha, IFNgamma and IL-10) in Down patients with coeliac disease. (PubMed id 16182624)1, 4 Cataldo F....Corsello G. (2005)
    109. Frequencies of the common promoter polymorphisms in cytokine genes in a Polish population. (PubMed id 16164695)1, 4 Kurzawski M....Drozdzik M. (2005)
    110. Modeling the influence of APOC3, APOE, and TNF polymorphisms on the risk of antiretroviral therapy-associated lipid disorders. (PubMed id 15809899)1, 4 Tarr P.E....Telenti A. (2005)
    111. -308GA and TNFB polymorphisms in acute respiratory distress syndrome. (PubMed id 16135717)1, 4 Gong M.N....Christiani D.C. (2005)
    112. Genetic predictors of coronary heart disease risk factors in premenopausal African-American women. (PubMed id 15825968)1, 4 Giger J.N....Acton R.T. (2005)
    113. Function associated transforming growth factor-beta gene polymorphism in chronic beryllium disease. (PubMed id 15750822)1, 4 Gaede K.I....Muller-Quernheim J. (2005)
    114. Cytokine polymorphisms do not influence acute rejection in renal transplantation under tacrolimus-based immunosuppression. (PubMed id 15919456)1, 4 Loucaidou M....Taube D. (2005)
    115. A recombined haplotype in the major histocompatibility region contains a cluster of genes conferring high susceptibility to ulcerative colitis in the Spanish population. (PubMed id 16116311)1, 4 Fernandez L....Martinez A. (2005)
    116. Effect of cytokines and chemokines (TGF-beta, TNF-alpha, IL-6, IL-10, MCP-1, RANTES) gene polymorphisms in kidney recipients on posttransplantation outcome: influence of donor-recipient match. (PubMed id 15848524)1, 4 Lacha J....Vitko S. (2005)
    117. Cytokine gene polymorphisms as potential risk and protective factors in renal cell carcinoma. (PubMed id 15784411)1, 4 Basturk B....Oral H.B. (2005)
    118. Pro- and anti-inflammatory cytokine gene polymorphism profiles in Bulgarian multiple sclerosis patients. (PubMed id 16183136)1, 4 Mihailova S....Naumova E. (2005)
    119. A comparison of methods for determining genotypes at the tumour necrosis factor-alpha-308, interleukin (IL)-1beta+3953, IL-6 -174 and IL-10 -1082/-819/-592 polymorphic loci. (PubMed id 15787640)1, 4 Bown M.J....Sayers R.D. (2005)
    120. Alterations in leukocyte function following surgical trauma: differentiation of distinct reaction types and association with tumor necrosis factor gene polymorphisms. (PubMed id 15699425)1, 4 Majetschak M....Schafer M. (2005)
    121. Cytokine gene polymorphisms and susceptibility to recurrent pregnancy loss in Iranian women. (PubMed id 15811521)1, 4 Kamali-Sarvestani E....Sarvari J. (2005)
    122. Risk of spontaneous preterm birth is associated with common proinflammatory cytokine polymorphisms. (PubMed id 15951664)1, 4 Engel S.A....Olshan A.F. (2005)
    123. TNF-857T, a genetic risk marker for acute anterior uveitis. (PubMed id 15851552)1, 4 Kuo N.W....Lightman S. (2005)
    124. Common genetic variants in the interleukin-6 and chitotriosidase genes are associated with the risk for serious infection in children undergoing therapy for acute myeloid leukemia. (PubMed id 16107886)1, 4 Lehrnbecher T....Schwabe D. (2005)
    125. [Association of TNFA polymorphisms with the outcomes of HBV infection] (PubMed id 16086278)1, 4 Liu Y....Li H. (2005)
    126. Genotypes of TNF-alpha, VEGF, hOGG1, GSTM1, and GSTT1: useful determinants for clinical outcome of bladder cancer. (PubMed id 15667866)1, 4 Kim E.J....Kim W.J. (2005)
    127. Cytokine gene polymorphisms in Japanese patients with hepatitis B virus infection--association between TGF-beta1 polymorphisms and hepatocellular carcinoma. (PubMed id 15763337)1, 4 Migita K....Eguchi K. (2005)
    128. The role of cytokine gene polymorphisms in determining disease susceptibility and phenotype in inflammatory bowel disease. (PubMed id 15842590)1, 4 Cantor M.J....Bernstein C.N. (2005)
    129. Haplotype analysis of a 100 kb region spanning TNF-LTA identifies a polymorphism in the LTA promoter region that is associated with atopic asthma susceptibility in Japan. (PubMed id 15969671)1, 4 Migita O....Arinami T. (2005)
    130. Immune response gene polymorphisms in renal transplant recipients. (PubMed id 16378074)1, 4 Dmitrienko S....Keown P.A. (2005)
    131. Polymorphisms in inflammation genes and bladder cancer: from initiation to recurrence, progression, and survival. (PubMed id 16110031)1, 4 Leibovici D....Wu X. (2005)
    132. Gene polymorphisms and serological markers of patients with active Crohn's disease in a clinical trial of antisense to ICAM-1. (PubMed id 15958080)1, 4 Yacyshyn B.R....Tami J.A. (2005)
    133. Dominance of high-producing interleukin 6 and low-producing interleukin 10 and interferon gamma alleles in glucose-6-phosphate dehydrogenase-deficient trauma patients. (PubMed id 15718915)1, 4 Upperman J.S....Spolarics Z. (2005)
    134. Relationship between cytokines gene polymorphism and susceptibility to hepatitis B virus intrauterine infection. (PubMed id 16232344)1, 4 Zhu Q.R....Dong Z.Q. (2005)
    135. The cytokine gene polymorphisms in patients with chronic kidney graft rejection. (PubMed id 15814282)1, 4 Pawlik A....Gawronska-Szklarz B. (2005)
    136. Lack of association between pro-inflammatory cytokine (IL-6, IL-8 and TNF-alpha) gene polymorphisms and Graves' disease. (PubMed id 16313297)1, 4 Chen R.H....Tsai F.J. (2005)
    137. Polymorphism in the genes of alpha and beta tumor necrosis factors (TNF-alpha and TNF-beta) and gamma interferon (IFN-gamma) among Iranian women with breast cancer. (PubMed id 15890243)1, 4 Kamali-Sarvestani E....Talei A.R. (2005)
    138. [On the association of tumor necrosis factor-alpha gene polymorphisms with the susceptibility to silicosis] (PubMed id 16235536)1, 4 Wang D.J....Sun M. (2005)
    139. Association of the major histocompatibility complex with response to infliximab therapy in rheumatoid arthritis patients. (PubMed id 15077289)1, 4 Martinez A....Fernandez-Gutierrez B. (2004)
    140. TLR4 and TNF-alpha polymorphisms are associated with an increased risk for severe sepsis following burn injury. (PubMed id 15520404)1, 4 Barber R.C....Horton J.W. (2004)
    141. Genotype announcement in a genetic polymorphism study for health checkup examinees at Nagoya University Hospital. (PubMed id 15279067)1, 4 Nishio K....Hamajima N. (2004)
    142. Cytokine gene polymorphisms and breast cancer susceptibility and prognosis. (PubMed id 15265021)1, 4 Smith K.C....Howell W.M. (2004)
    143. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    144. Influence of recipient and donor IL-1alpha, IL-4, and TNFalpha genotypes on the incidence of acute renal allograft rejection. (PubMed id 14693849)1, 4 Lee H....Newstead C.G. (2004)
    145. Cytokine gene polymorphisms and risks of acute rejection and delayed graft function after kidney transplantation. (PubMed id 15599305)1, 4 Alakulppi N.S....Laine J.T. (2004)
    146. Genetic basis of tobacco smoking: strong association of a specific major histocompatibility complex haplotype on chromosome 6 with smoking behavior. (PubMed id 15339882)1, 4 Fust G....Yu C.Y. (2004)
    147. [Genetic polymorphisms of alcohol-metabolizing enzymes and cytokines in patients with alcohol induced pancreatitis and alcoholic liver cirrhosis] (PubMed id 15220553)1, 4 Kim M.S....Lee M.S. (2004)
    148. IL-10 haplotypes as possible predictors of spontaneous clearance of HCV infection. (PubMed id 14698136)1, 4 Mangia A....Andriulli A. (2004)
    149. Tumor necrosis factor alpha gene polymorphism is associated with cerebral infarction. (PubMed id 14992821)1, 4 Um J.Y. and Kim H.M. (2004)
    150. Association between the TNF-2 allele and a better survival in cardiogenic shock. (PubMed id 15189946)1, 4 Appoloni O....Vincent J.L. (2004)
    151. Ethnic differences of polymorphisms in cytokine and innate immune system genes in pregnant women. (PubMed id 15292002)1, 4 Nguyen D.P....Witkin S.S. (2004)
    152. The influence of tumor necrosis factor -308 and C-reactive protein G1059C gene variants on serum concentration of C-reactive protein: evidence for an age-dependent association. (PubMed id 15469865)1, 4 Araujo F....Mansur A.J. (2004)
    153. The TNF-863A allele strongly associates with anticentromere antibody positivity in scleroderma. (PubMed id 14872499)1, 4 Sato H....Welsh K.I. (2004)
    154. Cytokine gene polymorphisms influence mucosal cytokine expression, gastric inflammation, and host specific colonisation during Helicobacter pylori infection. (PubMed id 15247172)1, 4 Rad R....Prinz C. (2004)
    155. Renovascular disease is associated with low producer genotypes of the anti-inflammatory cytokine interleukin-10. (PubMed id 15104679)1, 4 George S....Varghese Z. (2004)
    156. Complex genetic predisposition in adult and juvenile rheumatoid arthritis. (PubMed id 15018649)1, 4 Miterski B....Epplen J.T. (2004)
    157. Functional promoter region polymorphism of the proinflammatory chemokine IL-8 gene associates with Parkinson's disease in the Irish. (PubMed id 15120188)1, 4 Ross O.A....Gibson J.M. (2004)
    158. Allele 2 of the interleukin-1 receptor antagonist gene is associated with early gastric cancer. (PubMed id 15570075)1, 4 Glas J....Folwaczny C. (2004)
    159. Cytokine gene polymorphism and early graft rejection in liver transplant recipients. (PubMed id 15621151)1, 4 Karasu Z....Tokat Y. (2004)
    160. Cytokine gene polymorphisms in recurrent pregnancy loss of unknown cause. (PubMed id 15214940)1, 4 Prigoshin N....Testa R. (2004)
    161. Association between presenilin-1 -48C/T polymorphism and Down's syndrome. (PubMed id 15308304)1, 4 Lucarelli P....Curatolo P. (2004)
    162. Impact of donor and recipient cytokine genotypes on renal allograft outcome. (PubMed id 15194285)1, 4 Ligeiro D....Trindade H. (2004)
    163. HLA and cytokine gene polymorphisms are independently associated with responses to hepatitis B vaccination. (PubMed id 15057902)1, 4 Wang C....Kaslow R.A. (2004)
    164. Early failure of dental implants and TNF-alpha (G-308A) gene polymorphism. (PubMed id 15017311)1, 4 Campos M.I....Line S.R. (2004)
    165. Association analysis of the -308G>A promoter polymorphism of the tumor necrosis factor alpha (TNF-alpha) gene in Japanese patients with schizophrenia. (PubMed id 14767724)1, 4 Hashimoto R....Kunugi H. (2004)
    166. Association of polymorphic MHC microsatellites with GVHD, survival, and leukemia relapse in unrelated hematopoietic stem cell transplant donor/recipient pairs matched at five HLA loci. (PubMed id 15009808)1, 4 Li S....Inoko H. (2004)
    167. Gene polymorphisms in pro-inflammatory cytokines are associated with systemic inflammation in patients with severe periodontal infections. (PubMed id 15341923)1, 4 D'Aiuto F....Tonetti M.S. (2004)
    168. Neither the tumor necrosis factor alpha-308 A/G polymorphism nor the alpha2-macroglobulin polymorphism was associated with late-onset Alzheimer's disease in the Chinese population. (PubMed id 15468911)1, 4 Zhang P....Wang L. (2004)
    169. The influence of genetic variation in the HLA-DRB1 and LTA-TNF regions on the response to treatment of early rheumatoid arthritis with methotrexate or etanercept. (PubMed id 15457442)1, 4 Criswell L.A....Bridges S.L. (2004)
    170. HLA-DQ6 and ingestion of contaminated water: possible gene-environment interaction in an outbreak of Leptospirosis. (PubMed id 15014429)1, 4 Lingappa J....McNicholl J. (2004)
    171. Analysis of tumor necrosis factor-alpha, transforming growth factor-beta 1, interleukin-10, and interferon-gamma polymorphisms in patients with alcoholic chronic pancreatitis. (PubMed id 15066699)1, 4 Schneider A....Whitcomb D.C. (2004)
    172. Gene interactions and stroke risk in children with sickle cell anemia. (PubMed id 14615367)1, 4 Hoppe C....Styles L. (2004)
    173. A NOTCH4 association with multiple sclerosis is secondary to HLA-DR*1501. (PubMed id 14651518)1, 4 Duvefelt K....Hillert J. (2004)
    174. Polymorphisms in the tumour necrosis factor gene are not associated with severity of inflammatory polyarthritis. (PubMed id 14962963)1, 4 Barton A....Silman A. (2004)
    175. Analysis of MHC genes in a Tunisian isolate with autoimmune thyroid diseases: implication of TNF -308 gene polymorphism. (PubMed id 15236755)1, 4 Bougacha-Elleuch N....Hammadi A. (2004)
    176. Tumor necrosis factor-alpha and interferon-gamma polymorphisms contribute to susceptibility to oral lichen planus. (PubMed id 14962095)1, 4 Carrozzo M....Gandolfo S. (2004)
    177. Role of cytokine gene polymorphism and hepatic transforming growth factor beta1 expression in recurrent hepatitis C after liver transplantation. (PubMed id 15207246)1, 4 Ben-Ari Z....Mor E. (2004)
    178. Interleukin-10 production genotype protects against acute persistent rejection after lung transplantation. (PubMed id 15135368)1, 4 Zheng H.X....Zeevi A. (2004)
    179. Promoter polymorphisms of tumor necrosis factor-alpha are associated with risk of gastric mucosa-associated lymphoid tissue lymphoma. (PubMed id 15146559)1, 4 Wu M.S....Lin J.T. (2004)
    180. TNFalpha polymorphism frequencies in HPV-associated cervical dysplasia. (PubMed id 14766265)1, 4 Kirkpatrick A....Glew S. (2004)
    181. [Relationship of endothelin-1 (ET-1) TaqI and tumor necrosis factor (TNF) a gene polymorphism with portal hypertension in liver cirrhosis.] (PubMed id 15623376)1, 4 Cheng Y.Q....Xiong P. (2004)
    182. Single nucleotide polymorphisms of the inflammatory cytokine genes in adults with chronic immune thrombocytopenic purpura. (PubMed id 15009068)1, 4 Satoh T....Kuwana M. (2004)
    183. Candidate genetic markers and the risk of restenosis after coronary angioplasty. (PubMed id 12899665)1, 4 Volzke H....Rettig R. (2004)
    184. Nonimmunologic complications and gene polymorphisms of immunoregulatory cytokines in long-term renal transplants. (PubMed id 15200452)1, 4 Babel N....Reinke P. (2004)
    185. Th2/Th3 cytokine genotypes are associated with pregnancy loss. (PubMed id 14969768)1, 4 Costeas P.A....Koumas L. (2004)
    186. TNF-alpha, TGF-beta, IL-10, IL-6, and INF-gamma alleles among African Americans and Cuban Americans. Report of the ASHI Minority Workshops: Part IV. (PubMed id 15603866)1, 4 Delaney N.L....Leffell M.S. (2004)
    187. Genetic polymorphisms and retinopathy of prematurity. (PubMed id 15161830)1, 4 Cooke R.W....Clark D. (2004)
    188. Association between the tumor necrosis factor-alpha -308 G/A gene polymorphism and migraine. (PubMed id 14718719)1, 4 Rainero I....Pinessi L. (2004)
    189. Influence of promoter variants of interleukin-10, interleukin-9, and tumor necrosis factor-alpha genes on respiratory syncytial virus bronchiolitis. (PubMed id 14722888)1, 4 Hoebee B....Kimman T.G. (2004)
    190. Analysis of 6 genetic loci for disease susceptibility in psoriatic arthritis. (PubMed id 15517637)1, 4 Alenius G.M....Samuelsson L. (2004)
    191. Cytokine gene polymorphisms in Taiwan. (PubMed id 15361128)1, 4 Trejaut J.A....Lin M. (2004)
    192. [Cytokine gene polymorphisms in Chinese patients with type I autoimmune hepatitis] (PubMed id 15161508)1, 4 Ma X. and Qiu D.K. (2004)
    193. Donor genomics influence graft events: the effect of donor polymorphisms on acute rejection and chronic allograft nephropathy. (PubMed id 15458467)1, 4 Hoffmann S....Becker B.N. (2004)
    194. [First results on the influence of polymorphisms at glutathione S-transferase, cytochrome P450, and tumor necrosis factor gene loci on the development of multiple head and neck cancer] (PubMed id 12548461)1, 4 Matthias C....Strange R.C. (2003)
    195. Study on the correlation of cytokine gene polymorphism with chronic periodontitis. (PubMed id 14966591)1, 4 Lin L....Yin L.Y. (2003)
    196. Variation in immune response genes and chronic Q fever. Concepts: preliminary test with post-Q fever fatigue syndrome. (PubMed id 12595908)1, 4 Helbig K.J....Marmion B.P. (2003)
    197. Lower rate of tumor necrosis factor-alpha -863A allele and higher concentration of tumor necrosis factor-alpha receptor 2 in first-degree relatives of subjects with type 2 diabetes. (PubMed id 12898475)1, 4 Costa A....Conget I. (2003)
    198. Polymorphism of the stress protein HSP70-2 gene is associated with the susceptibility to the nasopharyngeal carcinoma. (PubMed id 12691826)1, 4 Jalbout M....Chouchane L. (2003)
    199. Cytokine gene polymorphisms moderate responses to respiratory syncytial virus in adults. (PubMed id 12507818)1, 4 Gentile D.A....Skoner D.P. (2003)
    200. A clinical feature associated with polymorphisms of the TNF region in Japanese patients with palmoplantar pustulosis. (PubMed id 12691703)1, 4 Hashigucci K....Inoko H. (2003)
    201. Association of TNF-alpha promoter polymorphisms with the clearance of hepatitis B virus infection. (PubMed id 12915457)1, 2 Kim Y.J.... Shin H.D. (2003)
    202. Cytokine gene polymorphisms in heart transplantation: association of low IL-10 production genotype with Quilty effect. (PubMed id 12909463)1, 4 Plaza D.M....Garcia L.F. (2003)
    203. No evidence for a major effect of tumor necrosis factor alpha gene polymorphisms in periportal fibrosis caused by Schistosoma mansoni infection. (PubMed id 14500462)1, 4 Moukoko C.E....Chevillard C. (2003)
    204. Promoter polymorphism of IL-10 and severity of multiple sclerosis. (PubMed id 14616291)1, 4 Luomala M....Elovaara I. (2003)
    205. Genetic factors and asthma in aluminum smelter workers. (PubMed id 14655898)1, 4 Arnaiz N.O....Checkoway H. (2003)
    206. TNF, TNF receptor type 1, and allograft inflammatory factor-1 gene polymorphisms in Japanese patients with type 1 diabetes. (PubMed id 12559634)1, 4 Nishimura M....Nakamura N. (2003)
    207. The TNF-alpha -308, MCP-1 -2518 and TGF-beta1 +915 polymorphisms are not associated with the development of chronic lung disease in very low birth weight infants. (PubMed id 12944979)1, 4 Adcock K....Baier R.J. (2003)
    208. TNFA-TNFB haplotypes modify susceptibility to type I diabetes mellitus independently of HLA class II in a Moroccan population. (PubMed id 12622777)1, 4 Bouqbis L....Izaabel H. (2003)
    209. Influence of the TNF-alpha and TNF-beta polymorphisms upon infectious risk and outcome in surgical intensive care patients. (PubMed id 12906716)1, 4 Calvano J.E....Lowry S.F. (2003)
    210. Tumour necrosis factor-alpha gene -238G/A promoter polymorphism associated with a more rapid onset of lipodystrophy. (PubMed id 12478078)1, 4 Nolan D....Mallal S. (2003)
    211. Polymorphisms of the tumor necrosis factor receptors: no association with narcolepsy in German patients. (PubMed id 12601524)1, 4 Wieczorek S....Gencik M. (2003)
    212. Polymorphisms in tumour necrosis factor-alpha, transforming growth factor-beta, interleukin-10, interleukin-6, interferon-gamma, and outcome of hepatitis C virus infection. (PubMed id 12938195)1, 4 Barrett S....Crowe J. (2003)
    213. Human genetic polymorphisms and asymptomatic Plasmodium falciparum malaria in Gabonese schoolchildren. (PubMed id 12641410)1, 4 Mombo L.E....Krishnamoorthy R. (2003)
    214. Tumour necrosis factor-alpha gene polymorphisms and Alzheimer's disease. (PubMed id 12962917)1, 4 Culpan D....Wilcock G.K. (2003)
    215. Novel association of HLA-haplotypes with primary sclerosing cholangitis (PSC) in a southern European population. (PubMed id 14567462)1, 4 Neri T.M....Okolicsanyi L. (2003)
    216. -308 Nco I polymorphism of tumour necrosis factor alpha in overweight Caucasians. (PubMed id 14625134)1, 4 Morris A.M....Clifton P.M. (2003)
    217. Influence of cytokine and mannose binding protein gene polymorphisms on human T-cell leukemia virus type I (hTLV-I) provirus load in HTLV-I asymptomatic carriers. (PubMed id 12651071)1, 4 Nishimura M....Matsuoka M. (2003)
    218. [The correlation between Kawasaki disease and polymorphisms of Tumor necrosis factor alpha and interleukin-10 gene promoter] (PubMed id 14744383)1, 4 Yang J....Wang G.B. (2003)
    219. Prediction of genetic risk for hypertension. (PubMed id 12654703)1, 4 Izawa H....Yokota M. (2003)
    220. Tumour necrosis factor alpha and its promoter polymorphisms' role in the phenotypic expression of hemochromatosis. (PubMed id 12940442)1, 4 Distante S....Bell H. (2003)
    221. Genetic background of Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis: association of HLA-DRB1*0901 with microscopic polyangiitis. (PubMed id 12858454)1, 4 Tsuchiya N....Hashimoto H. (2003)
    222. Polymorphisms of tumor necrosis factor and myeloperoxidase genes in patients with chronic renal failure on peritoneal dialysis. (PubMed id 15068388)1, 4 Buraczynska K....Ksiazek A. (2003)
    223. Analysis of major histocompatibility complex and CTLA-4 alleles in Brazilian patients with primary biliary cirrhosis. (PubMed id 12911663)1, 4 Bittencourt P.L....Goldberg A.C. (2003)
    224. Population frequencies of single nucleotide polymorphisms (SNPs) in immuno-modulatory genes. (PubMed id 14566095)1, 4 Martin A.M....Weber B.L. (2003)
    225. [Cytokine gene polymorphism in sensitized kidney transplant recipients and its association with acute rejection episodes] (PubMed id 14625191)1, 4 Gu X.W....Qian J. (2003)
    226. The -308 polymorphism in the tumour necrosis factor (TNF) gene promoter region and ex vivo lipopolysaccharide-induced TNF expression and cytotoxic activity in Chilean patients with rheumatoid arthritis. (PubMed id 12595628)1, 4 Cuenca J....Aguillon J.C. (2003)
    227. Associations between cytokine gene polymorphisms and recurrent pregnancy loss. (PubMed id 12609526)1, 4 Daher S....DeLima M.G. (2003)
    228. Haplotypic analysis of the TNF locus by association efficiency and entropy. (PubMed id 12702205)1, 4 Ackerman H....Kwiatkowski D.P. (2003)
    229. Cytokine gene polymorphisms: association with psoriatic arthritis susceptibility and severity. (PubMed id 12746914)1, 2 Balding J.... FitzGerald O. (2003)
    230. No association between the -1031 polymorphism in the TNF-alpha promoter region and type 1 diabetes. (PubMed id 12770796)1, 4 Shbaklo H....Zalloua P.A. (2003)
    231. Promoter polymorphisms of the TNF-alpha (G-308A) and IL-6 (C-174G) genes predict the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study. (PubMed id 12829659)1, 4 Kubaszek A....Laakso M. (2003)
    232. [Role of polymorphism of certain cytokines in gastric cancer in Mexico. Preliminary results] (PubMed id 15127646)1, 4 Garza-Gonzalez E....el-Omar E. (2003)
    233. A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus. (PubMed id 12732844)1, 4 Watanabe I....Koga T. (2003)
    234. Tumour necrosis factor family genes in a phenotype of COPD associated with emphysema. (PubMed id 12661999)1, 4 Ferrarotti I....Luisetti M. (2003)
    235. Association between IL-1beta -511C/T and IL-1RA (86bp)n repeats polymorphisms and schizophrenia. (PubMed id 14563376)1, 4 Zanardini R....Gennarelli M. (2003)
    236. Genotyping for cytokine polymorphisms: allele frequencies in the Italian population. (PubMed id 12558814)1, 4 Uboldi de Capei M.U....Curtoni E.S. (2003)
    237. Cytokine gene polymorphisms associated with symptomatic parvovirus B19 infection. (PubMed id 14514772)1, 4 Kerr J.R....Hutchinson I.V. (2003)
    238. A combination of human leukocyte antigen DQB1*02 and the tumor necrosis factor alpha promoter G308A polymorphism predisposes to an insulin-deficient phenotype in patients with type 2 diabetes. (PubMed id 12788886)1, 4 Li H....Tuomi T. (2003)
    239. Cytokine polymorphisms and histologic expression in autopsy studies: contribution of TNF-alpha and TGF-beta 1 to the pathogenesis of autoimmune-associated congenital heart block. (PubMed id 12960355)1, 4 Clancy R.M....Buyon J.P. (2003)
    240. Tumor necrosis factor gene polymorphism is associated with enhanced systemic inflammatory response and increased cardiopulmonary morbidity after cardiac surgery. (PubMed id 14500138)1, 4 Tomasdottir H....Ricksten S.E. (2003)
    241. A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma. (PubMed id 12891537)1, 4 Machado J.C....Sobrinho-Simoes M. (2003)
    242. Combined analysis of cytokine genotype polymorphism and the level of expression with allograft function in African-American renal transplant patients. (PubMed id 12727482)1, 4 McDaniel D.O....Butkus D.E. (2003)
    243. Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. (PubMed id 14656967)1, 2 Xie T.... Hood L. (2003)
    244. Tumor necrosis factor alpha, its soluble receptor I, and -308 gene promoter polymorphism in patients with rheumatoid arthritis with or without amyloidosis: implications for the pathogenesis of nephropathy and anemia of chronic disease in reactive amyloidosis. (PubMed id 14613268)1, 4 Maury C.P....Hurme M. (2003)
    245. Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor alpha, NFKB1, and peroxisome proliferator-activated receptor gamma with colorectal cancer. (PubMed id 12839942)1, 4 Landi S....Canzian F. (2003)
    246. Lack of association of tumor necrosis factor alpha gene polymorphism in patients with rheumatoid arthritis in central Taiwan. (PubMed id 12750939)1, 4 Lo S.F....Tsai F.J. (2003)
    247. Tumor necrosis factor-alpha gene polymorphism at position -308 and schizophrenia in the Korean population. (PubMed id 12839521)1, 4 Pae C.U....Serretti A. (2003)
    248. [Relationship between tumor necrosis factor genetic polymorphisms and acute lymphocytic leukemia] (PubMed id 12917036)1, 4 Zhao H.Y....Guan Z.Z. (2003)
    249. Cytokine gene polymorphisms moderate illness severity in infants with respiratory syncytial virus infection. (PubMed id 12590978)1, 4 Gentile D.A....Skoner D.P. (2003)
    250. Tumor necrosis factor-alpha -308 gene polymorphism is associated with synthetic hemodialysis graft failure. (PubMed id 12580317)1, 4 Ram S....Kruger T.E. (2003)
    251. [Polymorphism of TNF-alpha (308 A/G), IL-10 (1082 A/G, 819 C/T 592 A/C), IL-6 (174 G/C), and IFN-gamma (874 A/T); genetically conditioned cytokine synthesis level in children with diabetes type 1] (PubMed id 12818128)1, 4 Siekiera U....Koehler B. (2002)
    252. Recipient cytokine genotypes for TNF-alpha and IL-10 and the minor histocompatibility antigens HY and CD31 codon 125 are not associated with occurrence or severity of acute GVHD in unrelated cord blood transplantation: a retrospective analysis. (PubMed id 12438965)1, 4 Kogler G....Dickinson A.M. (2002)
    253. TNFalpha-308A associated with shorter intervals of Plasmodium falciparum reinfections. (PubMed id 12135427)1, 4 Meyer C.G....Kremsner P.G. (2002)
    254. Risk of chemotherapy-induced pulmonary fibrosis is associated with polymorphic tumour necrosis factor-a2 gene. (PubMed id 12030733)1, 4 Libura J....Piguet P.F. (2002)
    255. [Polymorphism of the tumor necrosis factor alpha gene in patients with infiltrative tuberculosis and from the Bashkorstan populations] (PubMed id 12391840)1, 4 Bikmaeva A.R....Khusnutdinova E.K. (2002)
    256. Association of tumor necrosis factor-alpha gene promoter polymorphism with low attenuation areas on high-resolution CT in patients with COPD. (PubMed id 12171811)1, 4 Sakao S....Kuriyama T. (2002)
    257. Frequency of cytokine polymorphisms in populations from western Europe, Africa, Asia, the Middle East and South America. (PubMed id 12392859)1, 4 Meenagh A....Middleton D. (2002)
    258. Allele and haplotype frequency at human leucocyte antigen class I/II and immunomodulatory cytokine loci in patients with myelodysplasia and acute myeloid leukaemia: in search of an autoimmune aetiology. (PubMed id 12028020)1, 4 Gowans D....Bowen D. (2002)
    259. Association between the tumor necrosis factor locus and the clinical outcome of Leishmania chagasi infection. (PubMed id 12438370)1, 4 Karplus T.M....Wilson M.E. (2002)
    260. Influence of cytokine gene polymorphisms on the development of prostate cancer. (PubMed id 12067976)1, 4 McCarron S.L....Howell W.M. (2002)
    261. MICA rather than MICB, TNFA, or HLA-DRB1 is associated with susceptibility to psoriatic arthritis. (PubMed id 12022360)1, 4 Gonzalez S....Lopez-Larrea C. (2002)
    262. Differences in the genetic background of latent autoimmune diabetes in adults (LADA) and type 1 diabetes mellitus. (PubMed id 12270547)1, 4 Vatay A....Panczel P. (2002)
    263. Association of cytokine single nucleotide polymorphisms with B7 costimulatory molecules in kidney allograft recipients. (PubMed id 11906646)1, 4 Hutchings A....Benfield M.R. (2002)
    264. No association between the G308A polymorphism of the tumor necrosis factor-alpha gene and schizophrenia. (PubMed id 12451465)1, 4 Riedel M....Muller N. (2002)
    265. Association between TNFA polymorphism and the development of asthma in the Japanese population. (PubMed id 12091169)1, 4 Noguchi E....Arinami T. (2002)
    266. MHC susceptibility genes to IgA deficiency are located in different regions on different HLA haplotypes. (PubMed id 12370403)1, 4 De la Concha E.G....Fontan G. (2002)
    267. Tumor necrosis factor-alpha and interleukin-10 promoter polymorphisms in Epstein-Barr virus-associated gastric carcinoma. (PubMed id 11756988)1, 4 Wu M.S....Lin J.T. (2002)
    268. A study of five human cytokine genes in human essential hypertension. (PubMed id 12009575)1, 4 Frossard P.M....Lukic M.L. (2002)
    269. Polymorphisms of the TNF gene and the TNF receptor superfamily member 1B gene are associated with susceptibility to ulcerative colitis and Crohn's disease, respectively. (PubMed id 11904678)1, 4 Sashio H....Furuyama J. (2002)
    270. Lack of association between C-850T polymorphism of the gene encoding tumor necrosis factor-alpha and polycystic ovary syndrome. (PubMed id 12396555)1, 4 Korhonen S....Heinonen S. (2002)
    271. CD14 and TNfa promoter polymorphisms in patients with acute arthritis. Special reference to development of chronic spondyloarthropathy. (PubMed id 12492251)1, 4 Repo H....Leirisalo-Repo M. (2002)
    272. [Association of tumor necrosis factor microsatellites TNF with the susceptibility to and outcome of postoperative severe sepsis] (PubMed id 12126516)1, 4 Shu Q....Frank S. (2002)
    273. Susceptibility for and clinical manifestations of rheumatoid arthritis are associated with polymorphisms of the TNF-alpha, IL-1beta, and IL-1Ra genes. (PubMed id 11838837)1, 4 Cvetkovic J.T....Lefvert A.K. (2002)
    274. [Frequency of donor TNF-alpha gene polymorphism in patients with graft versus host disease following hematopoietic stem cell transplantation] (PubMed id 12513816)1, 4 Wang J.B....Lu D.P. (2002)
    275. Lack of association between IL-1 cluster and TNF-alpha gene polymorphisms and giant cell arteritis. (PubMed id 12102486)1, 4 Gonzalez-Gay M.A....Hajeer A.H. (2002)
    276. Susceptibility to primary sclerosing cholangitis in Brazil is associated with HLA-DRB1*13 but not with tumour necrosis factor alpha -308 promoter polymorphism. (PubMed id 12235090)1, 4 Bittencourt P.L....Goldberg A.C. (2002)
    277. Host genetic polymorphism analysis in cervical cancer. (PubMed id 12142377)1, 4 Calhoun E.S....Persing D.H. (2002)
    278. Polymorphisms in cytokine genes do not predict progression to end-stage heart failure in children. (PubMed id 15773449)1, 4 Webber S.A....Zeevi A. (2002)
    279. A positive response to infliximab in Crohn disease: association with a higher systemic inflammation before treatment but not with -308 TNF gene polymorphism. (PubMed id 12190096)1, 4 Louis E....Belaiche J. (2002)
    280. Association of the tumour necrosis factor alpha -308G/A polymorphism with the risk of diabetes in an elderly population-based cohort. (PubMed id 12058258)1, 4 Heijmans B.T....Slagboom P.E. (2002)
    281. Ethnic-specific genetic associations with pulmonary tuberculosis. (PubMed id 12404162)1, 4 Delgado J.C....Goldfeld A.E. (2002)
    282. Pharmacogenetic investigation of the TNF/TNF-receptor system in patients with chronic active Crohn's disease treated with infliximab. (PubMed id 12049175)1, 4 Mascheretti S....Schreiber S. (2002)
    283. Tumour necrosis factor receptor II polymorphism and juvenile idiopathic arthritis. (PubMed id 11961180)1, 4 Zeggini E....Donn R. (2002)
    284. Polymorphism Ncol in tumor necrosis factor B is associated with fasting glycemia and lipid parameters in healthy non-obese caucasian subjects. (PubMed id 12149604)1, 4 Kankova K....Vacha J. (2002)
    285. The CD14-260 C --> T promoter polymorphism co-segregates with the tumor necrosis factor-alpha (TNF-alpha)-308 G --> A polymorphism and is associated with the interleukin-1 beta (IL-1 beta) synthesis capacity of human leukocytes. (PubMed id 12101079)1, 4 Heesen M....Kunz D. (2002)
    286. [TNF-alpha PC-1 gene polymorphisms and pre-diabetes quantitative features in the Polish population] (PubMed id 12715715)1, 4 Wanic K....Sieradzki J. (2002)
    287. Multi-locus interactions predict risk for post-PTCA restenosis: an approach to the genetic analysis of common complex disease. (PubMed id 12082592)1, 4 Zee R.Y....Lindpainter K. (2002)
    288. Interleukin 1 and chronic rejection: possible genetic links in human heart allografts. (PubMed id 12095061)1, 4 Vamvakopoulos J.E....Metcalf S.M. (2002)
    289. Triplet repeat polymorphism in the transmembrane region of the MICA gene in celiac disease. (PubMed id 12074713)1, 4 Fernandez L....Gomez de la Concha E. (2002)
    290. Allele frequencies of polymorphisms of TNFA, IL-6, IL-10 and IFNG in an Italian Caucasian population. (PubMed id 12047360)1, 4 Poli F....Sirchia G. (2002)
    291. Association between the TNFalpha-308 A/G polymorphism and the onset-age of Alzheimer disease. (PubMed id 12116197)1, 4 Alvarez V....Coto E. (2002)
    292. Cytokine gene polymorphisms and acute human liver graft rejection. (PubMed id 12089714)1, 4 Warle M.C....Bouma G.J. (2002)
    293. Relationship of tumour necrosis factor alpha gene polymorphisms and neuropsychiatric lupus. (PubMed id 11958574)1, 4 May L.A....Manolios N. (2002)
    294. Tumor necrosis factor-alpha allele 2 shows an association with insulin-dependent diabetes mellitus in Latvians. (PubMed id 12021142)1, 4 Shtauvere-Brameus A....Sanjeevi C.B. (2002)
    295. [Influence of cytokine gene polymorphism on renal transplantation] (PubMed id 12133353)1, 4 Tian Y....Zhang Y. (2002)
    296. Novel alleles at the lymphotoxin alpha (LTalpha) locus mark extended HLA haplotypes in native Africans. (PubMed id 11250044)1, 4 Tang J....Kaslow R.A. (2001)
    297. Plasma tumor necrosis factor alpha levels and the -238*A promoter polymorphism in patients with antiphospholipid syndrome. (PubMed id 11246532)1, 4 Bertolaccini M.L....Hughes G.R. (2001)
    298. Different allelic frequencies of several cytokine genes in Hong Kong Chinese and Swedish Caucasians. (PubMed id 11528523)1, 4 Padyukov L....Hanson L.A. (2001)
    299. Cross-sectional study on cytokine polymorphisms, cytokine production after T-cell stimulation and clinical parameters in a random sample of a German population. (PubMed id 11354638)1, 4 Nieters A....Becker N. (2001)
    300. Lack of evidence for the association of tumor necrosis factor-alpha gene promoter polymorphism with calcium oxalate stone and bladder cancer patients. (PubMed id 11828995)1, 4 Tsai F.J....Chen W.C. (2001)
    301. Case-control study with narcoleptic patients and healthy controls who, like the patients, possess both HLA-DRB1*1501 and -DQB1*0602. (PubMed id 11285131)1, 4 Hohjoh H....Tokunaga K. (2001)
    302. Both genetic and clinical factors predict the development of graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. (PubMed id 11544434)1, 4 Socie G....Charron D. (2001)
    303. The effect of cytokine gene polymorphisms on pediatric heart allograft outcome. (PubMed id 11404167)1, 4 Awad M.R....Zeevi A. (2001)
    304. No association of tumor necrosis factor-alpha gene polymorphism and copd in Caucasian smokers and Japanese smokers. (PubMed id 11157631)1, 4 Teramoto S. and Ishii T. (2001)
    305. Association between genetic polymorphism of tumor necrosis factor-alpha and risk of oral submucous fibrosis, a pre-cancerous condition of oral cancer. (PubMed id 11808761)1, 4 Chiu C.J....Chen C.J. (2001)
    306. Lack of association between human longevity and polymorphisms of IL-1 cluster, IL-6, IL-10 and TNF-alpha genes in Finnish nonagenarians. (PubMed id 11640949)1, 4 Wang X.Y....Hervonen A. (2001)
    307. A study of cytokine gene polymorphisms and protein secretion in renal transplantation. (PubMed id 11316066)1, 4 Cartwright N.H....Kaminski E.R. (2001)
    308. Role of cytokine gene polymorphism in hepatitis C recurrence and allograft rejection among liver transplant recipients. (PubMed id 11391238)1, 4 Tambur A.R....Mor E. (2001)
    309. Association analysis of HLA-class II and class III gene polymorphisms in the susceptibility to mediterranean visceral leishmaniasis. (PubMed id 11334675)1, 4 Meddeb-Garnaoui A....Dellagi K. (2001)
    310. Genes of the class II and class III major histocompatibility complex are associated with typhoid fever in Vietnam. (PubMed id 11120931)1, 4 Dunstan S.J....Dougan G. (2001)
    311. Association between TNF-alpha promoter polymorphism and Helicobacter pylori cagA subtype infection. (PubMed id 11533078)1, 4 Yea S.S....Paik K.H. (2001)
    312. Donor cytokine genotype influences the development of acute rejection after renal transplantation. (PubMed id 11233912)1, 4 Marshall S.E....Welsh K.I. (2001)
    313. Polymorphism of Immune Response Genes as a Factor for Predisposition to Development of Diseases. (PubMed id 12687213)1, 4 Konenkov V.I....Smolnikova M.V. (2001)
    314. Genetic polymorphisms as biomarkers of sensitivity to inhaled sulfur dioxide in subjects with asthma. (PubMed id 11258696)1, 4 Winterton D.L....Koenig J.Q. (2001)
    315. Cytokine polymorphism and kidney graft survival at a single center. (PubMed id 11266927)1, 4 Neumann J....Garcia V. (2001)
    316. [Influence of genetic variation in the major histocompatibility complex on head and neck cancer susceptibility] (PubMed id 11602932)1, 4 Matthias C....Strange R.C. (2001)
    317. Is tumor necrosis factor genotype (TNFA2/TNFA2)a genetic prognostic factor of an unfavorable outcome in IgA nephropathy? (PubMed id 11748357)1, 4 Lee E.Y....Hong S.Y. (2001)
    318. Tumor necrosis factor alpha polymorphism associated with increased susceptibility to development of adult T-cell leukemia/lymphoma in human T-lymphotropic virus type 1 carriers. (PubMed id 11325850)1, 4 Tsukasaki K....Koeffler H.P. (2001)
    319. Lack of association of severe preeclampsia with maternal and fetal mutant alleles for tumor necrosis factor alpha and lymphotoxin alpha genes and plasma tumor necrosis factor alpha levels. (PubMed id 11349201)1, 4 Livingston J.C....Sibai B.M. (2001)
    320. TNF-alpha, IL-6, IFN-gamma, and IL-10 gene expression polymorphisms and the IL-4 receptor alpha-chain variant Q576R: effects on renal allograft outcome. (PubMed id 11544427)1, 4 Hahn A.B....Conti D.J. (2001)
    321. Cytokine gene polymorphism in patients with graft-versus-host disease. (PubMed id 11266928)1, 4 Tambur A.R....Klein T. (2001)
    322. The telomeric part of the HLA region predisposes to rheumatoid arthritis independently of the class II loci. (PubMed id 11165717)1, 4 Zanelli E....Giphart M.J. (2001)
    323. Association of tumor necrosis factor-alpha and interleukin-1 gene polymorphisms with silicosis. (PubMed id 11264025)1, 4 Yucesoy B....Luster M.I. (2001)
    324. Allele 2 of interleukin-1 receptor antagonist gene increases the risk of thyroid peroxidase antibodies in subacute thyroiditis. (PubMed id 11506478)1, 4 Luotola K....Hurme M. (2001)
    325. Tumour necrosis factor alpha promoter polymorphism at position -308 is not associated with actinic prurigo. (PubMed id 11722460)1, 4 Grabczynska S.A....Vaughan R.W. (2001)
    326. [Association of tumor necrosis factor microsatellite polymorphism with incidence and outcome of severe postoperative sepsis] (PubMed id 11798757)1, 4 Shu Q....Stueber F. (2000)
    327. A prospective study of genetic markers of susceptibility to infection and inflammation, and the severity, progression, and regression of coronary atherosclerosis and its response to therapy. (PubMed id 11199329)1, 4 Elghannam H....Marian A.J. (2000)
    328. [Study on the relationship between a polymorphism of tumor necrosis factor-alpha gene and the pathogenesis of polycystic ovary syndrome] (PubMed id 11775944)1, 4 Mao W....Chen Y. (2000)
    329. Association of the TNF-alpha-308 (G-->A) polymorphism with self-reported history of childhood asthma. (PubMed id 11153913)1, 4 Winchester E.C....Kessling A.M. (2000)
    330. Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B. (PubMed id 11118029)1, 4 Nejentsev S....Ilonen J. (2000)
    331. Genetic analysis of immunomodulating factors in sporadic Parkinson's disease. (PubMed id 11072751)1, 4 Kruger R....Riess O. (2000)
    332. Tumor necrosis factor alpha gene G-308A polymorphism, insulin resistance, and fasting plasma glucose in young, older, and diabetic Japanese men. (PubMed id 11145126)1, 4 Ishii T....Saruta T. (2000)
    333. An interleukin-1 genotype is associated with fatal outcome of meningococcal disease. (PubMed id 11023482)1, 4 Read R.C....Duff G.W. (2000)
    334. A new member of the Ig superfamily and a V-ATPase G subunit are among the predicted products of novel genes close to the TNF locus in the human MHC. (PubMed id 10202016)1, 2 Neville M.J. and Campbell R.D. (1999)
    335. A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'. (PubMed id 10205166)1, 2 Watts A.D.... Chaudhri G. (1999)
    336. High resolution crystal structure of a human tumor necrosis factor- alpha mutant with low systemic toxicity. (PubMed id 9442056)1, 2 Cha S.S.... Oh B.H. (1998)
    337. Crystal structure of TNF-alpha mutant R31D with greater affinity for receptor R1 compared with R2. (PubMed id 9488135)1, 2 Reed C....Weber I.T. (1997)
    338. Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha. (PubMed id 9034191)1, 2 Moss M.L.... Becherer J.D. (1997)
    339. Phosphorylation of the 26 kDa TNF precursor in monocytic cells and in transfected HeLa cells. (PubMed id 8597870)1, 2 Pocsik E.... Wallach D. (1995)
    340. Dense Alu clustering and a potential new member of the NF kappa B family within a 90 kilobase HLA class III segment. (PubMed id 8499947)1, 2 Iris F.J.M....Cohen D. (1993)
    341. Myristyl acylation of the tumor necrosis factor alpha precursor on specific lysine residues. (PubMed id 1402651)1, 2 Stevenson F.T.... Lovett D.H. (1992)
    342. Localization of the active site of human tumour necrosis factor (hTNF) by mutational analysis. (PubMed id 2009860)1, 2 Ostade X.V.... Fiers W. (1991)
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    345. Structure of tumour necrosis factor. (PubMed id 2922050)1, 2 Jones E.Y.... Walker N.P. (1989)
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    347. Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor. (PubMed id 3883195)1, 2 Shirai T.... Wallace R.B. (1985)
    348. Molecular cloning of the complementary DNA for human tumor necrosis factor. (PubMed id 3856324)1, 2 Wang A.M.... Mark D.F. (1985)
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    351. Molecular cloning and expression of human tumor necrosis factor and comparison with mouse tumor necrosis factor. (PubMed id 3932069)1, 2 Marmenout A.... Fiers W. (1985)
    352. Expression and distribution of tumor necrosis factor alpha in human lumbar intervertebral discs: a study in surgical specimen and autopsy controls. (PubMed id 15626980)1, 9 Weiler C....Boos N. (2005)
    353. Alterations of biliary biochemical constituents and cytokines in infantile hepatitis syndrome. (PubMed id 17109502)1, 9 Ding Y....Zhang S.L. (2006)
    354. Effects of tumor necrosis factor-alpha (TNF alpha) in epidermal keratinocytes revealed using global transcriptional profiling. (PubMed id 15145954)1, 9 Banno T....Blumenberg M. (2004)
    355. The tumor necrosis factor polymorphism TNF (-308) is associated with susceptibility to meningococcal sepsis, but not with lethality. (PubMed id 19242354)1, 9 Read R.C....Wilson A.G. (2009)
    356. Influence of renal involvement on peripheral blood mononuclear cell expression behaviour of tumour necrosis factor-alpha and interleukin-6 in type 2 diabetic patients. (PubMed id 17911088)1, 9 Navarro J.F....Garcia J. (2008)
    357. Association between the level of circulating bioactive tumor necrosis factor alpha and the tumor necrosis factor alpha gene polymorphism at -308 in patients with rheumatoid arthritis treated with a tumor necrosis factor alpha inhibitor. (PubMed id 18438841)1, 9 Marotte H....Miossec P. (2008)
    358. Lack of TNFalpha mRNA expression in cervical cancer is not associated with loss of heterozygosity at 6p21.3, inactivating mutations or promoter methylation. (PubMed id 17560652)1, 9 Kloth J.N....Fleuren G.J. (2008)
    359. TNF polymorphism and bronchoalveolar lavage cell TNF-alpha levels in chronic beryllium disease and beryllium sensitization. (PubMed id 17208287)1, 9 Sato H....Maier L.A. (2007)
    360. Different methylation of the TNF-alpha promoter in cortex and substantia nigra: Implications for selective neuronal vulnerability. (PubMed id 18930140)1, 9 Pieper H.C....Wullner U. (2008)
    361. Association of high sensitivity C-reactive protein [hsCRP] and tumour necrosis factor-alpha [TNF-alpha] with carotid intimal medial thickness in subjects with different grades of glucose intolerance--the Chennai Urban Rural Epidemiology Study (CURES-31). (PubMed id 18328265)1, 9 Gokulakrishnan K....Mohan V. (2008)
    362. TNF-alpha gene promoter polymorphism at nucleotide -308 and the inflammatory response and oxidative stress induced by cardiac surgery: role of heart failure and medical treatment. (PubMed id 18450464)1, 9 Galinanes M....Hadjinikolaou L. (2008)
    363. TNFalpha genotype affects TNFalpha release, insulin sensitivity and the severity of liver disease in HCV chronic hepatitis. (PubMed id 16143422)1, 9 Valenti L....Fargion S. (2005)
    364. Association of bladder tumors and GA genotype of -308 nucleotide in tumor necrosis factor-alpha promoter with greater tumor necrosis factor-alpha expression. (PubMed id 15533517)1, 9 Jeong P....Kim W.J. (2004)
    365. Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kappaB. (PubMed id 15273737)1, 9 Schmelz K....Daniel P.T. (2004)
    366. The levels of tumor necrosis factor-alpha and interle ukin-6 in patients with isolated coronary artery ectasia. (PubMed id 19551157)1, 9 Aydin M....Aktop Z. (2009)
    367. Tumor necrosis factor-alpha -308G/A single nucleotide polymorphism and red-complex periodontopathogens are independently associated with increased levels of tumor necrosis factor-alpha in diseased periodontal tissues. (PubMed id 19076989)1, 9 Trombone A.P....Garlet G.P. (2008)
    368. Increased production of IL-1alpha and TNF-alpha in lipopolysaccharide-stimulated blood from obese patients with non-alcoholic fatty liver disease. (PubMed id 16564703)1, 9 Poniachik J....Videla L.A. (2006)
    369. Melanoma cell attachment, invasion, and integrin expression is upregulated by tumor necrosis factor alpha and suppressed by alpha melanocyte stimulating hormone. (PubMed id 12445207)1, 9 Zhu N....Haycock J.W. (2002)
    370. Characterization of synergistic induction of CX3CL1/f ractalkine by TNF-alpha and IFN-gamma in vascular endothelial cells: an essenti al role for TNF-alpha in post-transcriptional regulation of CX3CL1. (PubMed id 20231691)1, 9 Matsumiya T....Satoh K. (2010)
    371. Interleukin 12, interleukin 18, and tumor necrosis factor alpha release by alveolar macrophages: acute and chronic hypersensitivity pneumonitis. (PubMed id 19230467)1, 9 Ye Q....Guzman J. (2009)
    372. Elevated plasma levels of TNF-alpha and interleukin-6 in patients with diastolic dysfunction and glucose metabolism disorders. (PubMed id 19909503)1, 9 Dinh W....Lankisch M. (2009)
    373. TNFA and IL10 Gene Polymorphisms are not Associated w ith Periodontitis in Brazilians. (PubMed id 19771178)1, 9 Moreira P.R....Dutra W.O. (2009)
    374. Activation and overexpression of PARP-1 in circulating mononuclear cells promote TNF-alpha and IL-6 expression in patients with unstable angina. (PubMed id 18996291)1, 9 Huang D....Huang K. (2008)
    375. IL-2, TNF-alpha, and leptin: local versus systemic concentrations in NSCLC patients. (PubMed id 17913045)1, 9 Carpagnano G.E....Foschino Barbaro M.P. (2007)
    376. Plasma levels of tumor necrosis factor-alpha and interleukin-6 in obsessive compulsive disorder. (PubMed id 17497035)1, 9 Konuk N....Erdogan A. (2007)
    377. Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects. (PubMed id 12952969)1, 9 Rotter V....Smith U. (2003)
    378. A promoter mutation that increases transcription of the tumor necrosis factor-alpha gene is not associated with preterm delivery. (PubMed id 9369824)4, 9 Dizon-Townson D.S....Ward K. (1997)
    379. Differential effect of IL-1beta and TNF-alpha on the production of IL-6, IL-8 and PGE(2) in fibroblast-like synoviocytes and THP-1 m acrophages. (PubMed id 19697035)1, 9 Choi H.M....Kim K.S. (2010)
    380. Does interleukin-18 or tumour necrosis factor-alpha h ave an independent association with the risk of coronary heart disease? Results from a prospective study in New Zealand. (PubMed id 20096599)1, 9 Welsh P....Lowe G.D. (2010)
    381. Single nucleotide polymorphisms in TNF-alpha, TNFR2 g ene and TNF-alpha production in Asian Indians. (PubMed id 19811435)1, 9 Gupta R....Das S.N. (2009)
    382. [The level of TNF-alpha secretion of PBMC in patients with chronic hepatitis C and nonalcoholic fatty liver] (PubMed id 20104750)1, 9 Dong Y....Cheng Y. (2009)
    383. Relationship of transforming growth factor-beta(1) with tumour necrosis factor-alpha and endothelial activation in patients with stable renal transplantation. (PubMed id 18275506)1, 9 Palermo A....Cottone S. (2008)
    384. Cytokine regulation of mucin secretion in a human middle ear epithelial model. (PubMed id 18063379)1, 9 Samuel E.A....Kerschner J.E. (2008)
    385. Expression of S100A6 in cardiac myocytes limits apoptosis induced by tumor necrosis factor-alpha. (PubMed id 18753141)1, 9 Tsoporis J.N....Parker T.G. (2008)
    386. The evaluation of cystatin C, IL-1beta, and TNF-alpha levels in total saliva and gingival crevicular fluid from 11- to 16-year-old children. (PubMed id 18454664)1, 9 Ulker A.E....Demirtas S. (2008)
    387. [The effect of TNF-alpha & IL-8 in the pathogenesis of allergic rhinitis] (PubMed id 17285966)1, 9 Wang Z. (2006)
    388. Expression and regulation of tumor necrosis factor alpha in normal and malignant ovarian epithelium. (PubMed id 16505113)1, 9 Szlosarek P.W....Balkwill F.R. (2006)
    389. Effects of proinflammatory cytokines on the expression of mineralization markers and heme oxygenase-1 in human pulp cells. (PubMed id 16410066)1, 9 Min K.S....Kim E.C. (2006)
    390. Butyrate suppresses tumor necrosis factor alpha produ ction by regulating specific messenger RNA degradation mediated through a cis-a cting AU-rich element. (PubMed id 16142751)6, 9 Fukae J....Koike T. (2005)
    391. TNF-alpha and TGF-beta1 gene polymorphisms and renal allograft rejection in Koreans. (PubMed id 15546338)1, 9 Park J.Y....Ahn C. (2004)
    392. Cytokine gene polymorphisms in hemodialysis patients: association with comorbidity, functionality, and serum albumin. (PubMed id 15086488)1, 9 Balakrishnan V.S....Pereira B.J. (2004)
    393. Regulation of eotaxin gene expression by TNF-alpha and IL-4 through mRNA stabilization: involvement of the RNA-binding protein HuR. (PubMed id 14530362)1, 9 Atasoy U....Stellato C. (2003)
    394. Association between measures of insulin sensitivity and circulating levels of interleukin-8, interleukin-6 and tumor necrosis factor-alpha. Effect of weight loss in obese men. (PubMed id 12720537)1, 9 Bruun J.M....Richelsen B. (2003)
    395. Relative abundance and patterns of correlation among six cytokines in pleural fluid measured by cytometric bead array. (PubMed id 12851716)1, 9 Aoe K....Takeyama H. (2003)
    396. Tumor necrosis factor alpha (TNF-alpha)-induced RANTES chemokine expression via activation of NF-kappaB and p38 MAP kinase: roles of TNF-alpha in alcoholic liver diseases. (PubMed id 12663241)1, 9 Hirano F....Makino I. (2003)
    397. Tumor necrosis factor alpha promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease. (PubMed id 11832442)1, 9 Valenti L....Fargion S. (2002)
    398. Tumor necrosis factor alpha decreases, and interleukin-10 increases, the sensitivity of human monocytes to dexamethasone: potential regulation of the glucocorticoid receptor. (PubMed id 10443688)1, 9 Franchimont D....Geenen V. (1999)
    399. IL-8 production by macrophages is synergistically enh anced when cigarette smoke is combined with TNF-alpha. (PubMed id 19874800)1, 9 Sarir H....Folkerts G. (2010)
    400. Tumor necrosis factor-alpha enhances both epithelial- mesenchymal transition and cell contraction induced in A549 human alveolar epit helial cells by transforming growth factor-beta1. (PubMed id 20128678)1, 9 Yamauchi Y....Nagase T. (2010)
    401. Tumor necrosis factor alpha (-308), interleukin-6 (-1 74) and interleukin-10 (-1082) gene polymorphisms in polycystic ovary syndrome. (PubMed id 20189706)1, 9 Vural P....AkgA1l C. (2010)
    402. Associations of circulating TNFalpha and IL-18 with m yocardial infarction and cardiovascular risk markers: the Glasgow Myocardial In farction Study. (PubMed id 19581111)1, 9 Welsh P....Lowe G. (2009)
    403. G9a and HP1 couple histone and DNA methylation to TNFalpha transcription silencing during endotoxin tolerance. (PubMed id 18809684)1, 9 El Gazzar M....McCall C.E. (2008)
    404. Thalidomide suppressed IL-1beta while enhancing TNF-alpha and IL-10, when cells in whole blood were stimulated with lipopolysaccharide. (PubMed id 18668392)1, 9 Shannon E....Kamath B. (2008)
    405. The role of vascular endothelial growth factor, tumor necrosis factor alpha and interleukin-6 in pathogenesis of diabetic retinopathy. (PubMed id 17716775)1, 9 Mysliwiec M....Raczynska K. (2008)
    406. Tumor necrosis factor-alpha (TNF-alpha) induces integrin CD11b/CD18 (Mac-1) up-regulation and migration to the CC chemokine CCL3 (MIP-1alpha) on human neutrophils through defined signalling pathways. (PubMed id 18164590)1, 9 Montecucco F....Ottonello L. (2008)
    407. HIV-1 Tat protein induces TNF-alpha and IL-10 production by human macrophages: differential implication of PKC-betaII and -delta isozymes and MAP kinases ERK1/2 and p38. (PubMed id 18692180)1, 9 Leghmari K....Bahraoui E. (2008)
    408. Overexpression of TNF-alpha and TNFRII in invasive micropapillary carcinoma of the breast: clinicopathological correlations. (PubMed id 18764880)1, 9 Cui L.F....Fu L. (2008)
    409. Mechanical stress induces tumor necrosis factor-{alpha} production through Ca2+ release-dependent TLR2 signaling. (PubMed id 18550705)1, 9 Kim H.G....Chung D.K. (2008)
    410. Interleukin-10 and tumor necrosis factor-alpha polymorphisms in vascular access failure in patients on hemodialysis: preliminary data in Korea. (PubMed id 18303205)1, 9 Sung S.A....Lee S.Y. (2008)
    411. Association of TNF polymorphisms with sarcoidosis, its prognosis and tumour necrosis factor (TNF)-alpha levels in Asian Indians. (PubMed id 18062795)1, 9 Sharma S....Sharma S.K. (2008)
    412. Association of TNF-alpha with severe respiratory syncytial virus infection and bronchial asthma. (PubMed id 18811622)1, 9 Puthothu B....Heinzmann A. (2008)
    413. Analysis of interleukin-8, interleukin-10, and tumor necrosis factor-alpha in the cerebrospinal fluid of patients with cervical spondylotic myelopathy. (PubMed id 18391721)1, 9 Ito K....Ishiguro N. (2008)
    414. LPS induces interleukin-6 and interleukin-8 but not tumor necrosis factor-alpha in human adipocytes. (PubMed id 18060802)1, 9 Hoch M....Linscheid P. (2008)
    415. Association between TNF and IL-1 bloc polymorphisms and plasma MCP-1 concentration. (PubMed id 16814297)1, 9 Berrahmoune H....Visvikis-Siest S. (2007)
    416. Circulating concentrations of adiponectin and tumor necrosis factor-alpha in gestational diabetes mellitus. (PubMed id 17454170)1, 9 Altinova A.E....Arslan M. (2007)
    417. Tumour necrosis factor-alpha (TNFalpha) and interleukin-10 are crucial mediators in post-operative systemic inflammatory response and determine the occurrence of complications after major abdominal surgery. (PubMed id 17428673)1, 9 Dimopoulou I....Giamarellos-Bourboulis E.J. (2007)
    418. TNF-alpha (-308 G/A) and CD14 (-159T/C) polymorphisms in the bronchial responsiveness of Korean children with asthma. (PubMed id 17196641)1, 9 Hong S.J....Park C.S. (2007)
    419. NRAMP1 and TNF-alpha polymorphisms and susceptibility to tuberculosis in Thais. (PubMed id 17298451)1, 9 Vejbaesya S....Sermduangprateep C. (2007)
    420. Interleukin-10 modulates pro-apoptotic effects of TNF-alpha in human articular chondrocytes in vitro. (PubMed id 18023359)1, 9 John T....Schulze-Tanzil G. (2007)
    421. Glucosamine sulfate inhibits TNF-alpha and IFN-gamma- induced production of ICAM-1 in human retinal pigment epithelial cells in vitro . (PubMed id 16431966)7, 9 Chen J.T....Lu D.W. (2006)
    422. Do adiponectin, TNFalpha, leptin and CRP relate to insulin resistance in pregnancy? Studies in women with and without gestational diabetes, during and after pregnancy. (PubMed id 16170833)1, 9 McLachlan K.A....Alford F.P. (2006)
    423. Vitamin D-induced up-regulation of tumour necrosis factor alpha (TNF-alpha) in prostate cancer cells. (PubMed id 15904673)1, 9 Golovko O....Tuohimaa P. (2005)
    424. Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor. (PubMed id 15755722)1, 9 Zhang W....Min W. (2005)
    425. Differential effect of IL10 and TNF{alpha} genotypes on determining susceptibility to discoid and systemic lupus erythematosus. (PubMed id 15800006)1, 9 Suarez A....Gutierrez C. (2005)
    426. Association of TNF-alpha and TNF-beta gene polymorphism with steroid receptor expression in breast cancer patients. (PubMed id 15999154)1, 9 Kamali-Sarvestani E....Talei A.A. (2005)
    427. The effects of peritoneal dialysis and hemodialysis on serum tumor necrosis factor-alpha, interleukin-6, interleukin-10 and C-reactive-protein levels. (PubMed id 15223612)1, 9 Borazan A....Yilmaz A. (2004)
    428. An immunoglobulin agent (IVIG) inhibits NF-kappaB activation in cultured endothelial cells of coronary arteries in vitro. (PubMed id 15167972)1, 9 Ichiyama T....Furukawa S. (2004)
    429. Tumour necrosis factor-alpha gene promoter region -308 and -376 G-->A polymorphisms in Behcet's disease. (PubMed id 14727453)1, 9 Duymaz-Tozkir J....Saruhan-Direskeneli G. (2003)
    430. High innate production of interleukin-10 and tumor necrosis factor-alpha contributes to susceptibility for non-paraneoplastic Lambert-Eaton myasthenic syndrome. (PubMed id 12864989)1, 9 Wirtz P.W....Verschuuren J.J. (2003)
    431. TNF-alpha plus IFN-gamma induce connexin43 expression and formation of gap junctions between human monocytes/macrophages that enhance physiological responses. (PubMed id 12538692)1, 9 Eugenin E.A....Saez J.C. (2003)
    432. Modulation of toll-like receptor 4 expression on human monocytes by tumor necrosis factor and interleukin-6: tumor necrosis factor evokes lipopolysaccharide hyporesponsiveness, whereas interleukin-6 enhances lipopolysaccharide activity. (PubMed id 12923493)1, 9 Tamandl D....Spittler A. (2003)
    433. Serum levels of interleukin-1 receptor antagonist and tumor necrosis factor-alpha are elevated in children with Langerhans cell histiocytosis. (PubMed id 12794527)1, 9 Rosso D.A....Braier J.L. (2003)
    434. Tumor necrosis factor-alpha induces early-onset endothelial adhesivity by protein kinase Czeta-dependent activation of intercellular adhesion molecule-1. (PubMed id 12714560)1, 9 Javaid K....Malik A.B. (2003)
    435. Urokinase plasminogen activator mRNA is induced by IL-1alpha and TNF-alpha in in vitro acantholysis. (PubMed id 12930304)1, 9 Feliciani C....Tulli A. (2003)
    436. Relationship between circulating serum soluble interleukin-6 receptor and the angiogenic cytokines basic fibroblast growth factor and vascular endothelial growth factor in multiple myeloma. (PubMed id 12574959)1, 9 Alexandrakis M.G....Kyriakou D.S. (2003)
    437. Lack of association of TNF-238A and -308A in Japanese patients with psoriasis vulgaris, psoriatic arthritis and generalized pustular psoriasis. (PubMed id 12234707)1, 9 Nishibu A....Kaneko F. (2002)
    438. TNF-alpha sensitizes HT-29 colonic epithelial cells to intestinal lactobacilli. (PubMed id 12192111)1, 9 McCracken V.J....Gaskins H.R. (2002)
    439. Recurrent miscarriage and variant alleles of mannose binding lectin, tumour necrosis factor and lymphotoxin alpha genes. (PubMed id 11737072)1, 9 Baxter N....Summerfield J.A. (2001)
    440. [The postburn changes of the plasma levels of PGE2 and TNF alpha in burn patients] (PubMed id 11774822)1, 9 Chen H....Xu W. (2001)
    441. No strong association between alleles of tumour necrosis factor alpha and interleukin-1 receptor antagonist and corneal melting associated with systemic vasculitis. (PubMed id 10729297)4, 9 McKibbin M....Morrell A.J. (2000)
    442. Combined analysis of polymorphisms of the tumor necrosis factor-alpha and interleukin-10 promoter regions and polymorphic xenobiotic metabolizing enzymes in psoriasis. (PubMed id 10469306)4, 9 Reich K....Neumann C. (1999)
    443. Relation of a TNF gene polymorphism to severe sepsis in trauma patients. (PubMed id 10450735)4, 9 Majetschak M....Stuber F. (1999)
    444. Regulation of TNFalpha and TGFbeta-1 gene transcription by HIV-1 Tat in CNS cells. (PubMed id 9670843)1, 9 Sawaya B.E....Amini S. (1998)
    445. Analysis of the synergistic stimulation of mouse macrophage proliferation by macrophage colony-stimulating factor (CSF-1) and tumor necrosis factor alpha (TNF-alpha). (PubMed id 8336080)1, 9 Guilbert L.J....Garcia-Lloret M. (1993)
    446. Soluble factors derived from tumor mammary cell lines induce a stromal mammary adipose reversion in human and mice adipose cells. Po ssible role of TGF-beta1 and TNF-alpha. (PubMed id 19649705)1, 9 Guerrero J....MartA-nez J. (2010)
    447. Association between toll-like receptor polymorphisms and serum levels of tumor necrosis factor-alpha and its soluble receptors in ob ese children. (PubMed id 20357716)1, 9 Jermendy A....Cseh K. (2010)
    448. Interleukin-6 (G-174C) and tumour necrosis factor-alp ha (G-308A) gene polymorphisms in geriatric patients with chronic periodontitis . (PubMed id 19555357)1, 9 Costa A.M....Bezerra A.C. (2010)
    449. The association of tumor necrosis factor alpha recept or 2 and tumor necrosis factor alpha with insulin resistance and the influence of adipose tissue biomarkers in humans. (PubMed id 19846171)1, 9 Hivert M.F....Meigs J.B. (2010)
    450. Regulated on activation, normal T cell expressed and secreted and tumor necrosis factor-alpha in septic neonates. (PubMed id 19847187)1, 9 Shouman B. and Badr R. (2010)
    451. Interactions among type I and type II interferon, tum or necrosis factor, and beta-estradiol in the regulation of immune response-rel ated gene expressions in systemic lupus erythematosus. (PubMed id 19121222)1, 9 Lee H.M....Nishimoto N. (2009)
    452. [TNF alfa polymorphism and course of ulcerative colit is] (PubMed id 19606693)1, 9 JaA8ocha A.8....Fiedorowicz E. (2009)
    453. Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells. (PubMed id 19122175)1, 9 Di Francesco L....Patrignani P. (2009)
    454. TNFalpha and its receptors in psoriatic skin, before and after treatment with etanercept. (PubMed id 20074459)1, 9 Caldarola G....Feliciani C. (2009)
    455. Mechanisms of leukocyte accumulation and activation in chorioamnionitis: interleukin 1beta and tumor necrosis factor alpha enhance in term decidua. (PubMed id 19164476)1, 9 Arcuri F....Lockwood C.J. (2009)
    456. The repeatability of interleukin-6, tumor necrosis factor-alpha, and C-reactive protein in COPD patients over one year. (PubMed id 19436686)1, 9 Kolsum U....Singh D. (2009)
    457. Psychiatric morbidity associated with some cytokines (IL-1beta, IL-12, IL-18 and TNF-alpha) among rheumatoid arthritis patients. (PubMed id 20306665)1, 9 El-Tantawy A.M....Amin R.T. (2008)
    458. Influence of cytokine gene polymorphisms on IgA nephropathy. (PubMed id 18300111)1, 9 Bantis C....Ivens K. (2008)
    459. Sepsis syndrome and death in trauma patients are associated with variation in the gene encoding tumor necrosis factor. (PubMed id 18434886)1, 9 Menges T....Bein G. (2008)
    460. Modulation of TNF release by choline requires alpha7 subunit nicotinic acetylcholine receptor-mediated signaling. (PubMed id 18584048)1, 9 Parrish W.R....Pavlov V.A. (2008)
    461. Expression of TNF-alpha protein in omental and subcutaneous adipose tissue in obesity. (PubMed id 17935818)1, 9 Cao Y.L....Zhang J. (2008)
    462. Genetic polymorphisms of adiponectin and tumor necrosis factor-alpha and nonalcoholic fatty liver disease in Chinese people. (PubMed id 18565022)1, 9 Wong V.W....Chan H.L. (2008)
    463. CD300a/c regulate type I interferon and TNF-alpha secretion by human plasmacytoid dendritic cells stimulated with TLR7 and TLR9 ligands. (PubMed id 18535206)1, 9 Ju X....Clark G.J. (2008)
    464. Association between LTA, TNF and AGER polymorphisms and late diabetic complications. (PubMed id 18575614)1, 9 Lindholm E....Agardh C.D. (2008)
    465. Adiponectin protects against angiotensin II or tumor necrosis factor alpha-induced endothelial cell monolayer hyperpermeability: role of cAMP/PKA signaling. (PubMed id 18292388)1, 9 Xu S.Q....Goldstein B.J. (2008)
    466. Characterization of tumour necrosis factor-alpha genetic variants and mRNA expression in patients with severe sepsis. (PubMed id 18643840)1, 9 O'Dwyer M.J....Ryan T. (2008)
    467. Effect of the 252A>G polymorphism of the lymphotoxin-alpha gene on inflammatory markers of response to cigarette smoking in Korean healthy men. (PubMed id 17113059)1, 9 Jang Y....Lee J.H. (2007)
    468. Tumour necrosis factor alpha promoter polymorphisms and etanercept therapy in juvenile idiopathic arthritis. (PubMed id 16951943)1, 9 Schmeling H. and Horneff G. (2007)
    469. The expression of TNF-alpha and ICAM-1 in lesions of lichen planus and its implication. (PubMed id 18231758)1, 9 Chen X....Yue Q. (2007)
    470. Influence of the selective oestrogen receptor modulator (raloxifene hydrochloride) on IL-6, TNF-alpha, TGF-beta1 and bone turnover markers in the treatment of postmenopausal osteoporosis. (PubMed id 17823083)1, 9 Ozmen B....Hekimsoy Z. (2007)
    471. Associations between insulin resistance and TNF-alpha in plasma, skeletal muscle and adipose tissue in humans with and without type 2 diabetes. (PubMed id 17928988)1, 9 Plomgaard P....Pedersen B.K. (2007)
    472. Influence of TNF gene polymorphisms in Japanese patients with NASH and simple steatosis. (PubMed id 17395331)1, 9 Tokushige K....Shiratori K. (2007)
    473. Common TNF-alpha, IL-1 beta, PAI-1, uPA, CD14 and TLR4 polymorphisms are not associated with disease severity or outcome from Gram negative sepsis. (PubMed id 17877801)1, 9 Jessen K.M....Benfield T. (2007)
    474. Interaction between transmembrane TNF and TNFR1/2 mediates the activation of monocytes by contact with T cells. (PubMed id 17785864)1, 9 Rossol M....Wagner U. (2007)
    475. Tumor necrosis factor-alpha and interleukin-4 gene polymorphisms in Chinese patients with gout. (PubMed id 17631734)1, 9 Chen M.L....Huang C.M. (2007)
    476. A - 308 promoter polymorphism of tumor necrosis factor alpha gene does not associate with the susceptibility to psoriasis vulgaris. No difference either between psoriasis type I and type II patients. (PubMed id 17053845)1, 9 Baran W....Baran E. (2006)
    477. TNFalpha polymorphisms and risk of psoriatic arthritis. (PubMed id 16284098)1, 9 Rahman P....Gladman D. (2006)
    478. Serum IL-1beta, IL-2, and IL-6 in insulin-dependent diabetic children. (PubMed id 16864906)1, 9 Dogan Y....Gurgoze M.K. (2006)
    479. Transcriptional regulation of CD38 expression by tumor necrosis factor-alpha in human airway smooth muscle cells: role of NF-kappaB and sensitivity to glucocorticoids. (PubMed id 16571778)1, 9 Kang B.N....Kannan M.S. (2006)
    480. High serum TNF-alpha level in Type 2 diabetic patients with microangiopathy is associated with eNOS down-regulation and apoptosis in endothelial cells. (PubMed id 16260352)1, 9 Makino N....Abe N. (2005)
    481. Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis. (PubMed id 16203766)1, 9 Iversen P.O. and Wiig H. (2005)
    482. Induction of cytokine (interleukin-1alpha and tumor necrosis factor-alpha) and chemokine (CCL20, CCL27, and CXCL8) alarm signals after allergen and irritant exposure. (PubMed id 15679580)1, 9 Spiekstra S.W....Gibbs S. (2005)
    483. Relationship of obesity and visceral adiposity with serum concentrations of CRP, TNF-alpha and IL-6. (PubMed id 15955385)1, 9 Park H.S....Yu R. (2005)
    484. IL-17 and IL-17F modulate GM-CSF production by lung microvascular endothelial cells stimulated with IL-1beta and/or TNF-alpha. (PubMed id 15388258)1, 9 Numasaki M....Sasaki H. (2004)
    485. Critical paracrine interactions between TNF-alpha and IL-10 regulate lipopolysaccharide-stimulated human choriodecidual cytokine and prostaglandin E2 production. (PubMed id 12496396)1, 9 Sato T.A....Mitchell M.D. (2003)
    486. Modulation of IL-8 and RANTES release in human conjunctival epithelial cells: primary cells and cell line compared and contrasted. (PubMed id 12792476)1, 9 Smit E.E....Trocme S.D. (2003)
    487. Moderate alcohol consumption, glucose metabolism and lipolysis: the effect on adiponectin and tumor necrosis factor alpha. (PubMed id 15055475)1, 9 Avogaro A....Beltramello G. (2003)
    488. Effects of TNFalpha on expression of ICAM-1 in human airway epithelial cells in vitro: oxidant-mediated pathways and transcription factors. (PubMed id 14572618)1, 9 Krunkosky T.M....Adler K.B. (2003)
    489. Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2). (PubMed id 12591926)1, 9 Shi C.S. and Kehrl J.H. (2003)
    490. Association of plasma levels of tumor necrosis factor (TNF)-alpha and its soluble receptors, two polymorphisms of the TNF gene, with acute severe pancreatitis and early septic shock due to it. (PubMed id 12717265)1, 9 Dianliang Z....Baojun Y. (2003)
    491. TNF-alpha and TNF-beta gene polymorphisms in cerebral infarction. (PubMed id 14593215)1, 9 Um J.Y....Kim H.M. (2003)
    492. Frequencies of the tumor necrosis factor gene polymorphisms in the Korean population. (PubMed id 15061799)1, 9 Um J.Y. and Kim H.M. (2003)
    493. Extracellular ubiquitin inhibits the TNF-alpha response to endotoxin in peripheral blood mononuclear cells and regulates endotoxin hyporesponsiveness in critical illness. (PubMed id 12406900)1, 9 Majetschak M....Obertacke U. (2003)
    494. Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways. (PubMed id 12171600)1, 9 Knebel A....Cohen P. (2002)
    495. Polymorphisms in TNFA and TNFR2 affect outcome of unrelated bone marrow transplantation. (PubMed id 11979305)1, 9 Ishikawa Y....Juji T. (2002)
    496. Relevance of the selected cytokine release (TNF-alpha, IL-6, IFN-gamma, and IFN-alpha) to the exacerbation of bronchial asthma from airway mycotic infections. Predominant role of TFN-alpha? (PubMed id 12530117)1, 9 Liebhart J....Mal/olepszy J. (2002)
    497. IL-4, but not IL-13, modulates TARC (thymus and activation-regulated chemokine)/CCL17 and IP-10 (interferon-induced protein of 10kDA)/CXCL10 release by TNF-alpha and IFN-gamma in HaCaT cell line. (PubMed id 12441140)1, 9 Kakinuma T....Tamaki K. (2002)
    498. Role of tumour necrosis factor-alpha in insulin resistance during normal pregnancy. (PubMed id 12270556)1, 9 Melczer Z....Cseh K. (2002)
    499. Polymorphisms of the tumor necrosis factor-alpha gene promoter predict for outcome after thalidomide therapy in relapsed and refractory multiple myeloma. (PubMed id 12200397)1, 9 Neben K....Goldschmidt H. (2002)
    500. TNF and LTA gene polymorphisms reveal different risk in gastric and duodenal ulcer patients. (PubMed id 11781708)1, 9 Lanas A....Pena A.S. (2001)
    501. Increased risk of fibrosing alveolitis associated with interleukin-1 receptor antagonist and tumor necrosis factor-alpha gene polymorphisms. (PubMed id 10934117)4, 9 Whyte M....Di Giovine F. (2000)
    502. A TNF-alpha promoter polymorphism is associated with juvenile onset psoriasis and psoriatic arthritis. (PubMed id 9326391)4, 9 Hohler T....Marker-Hermann E. (1997)
    503. Expression and functional significance of tumor necrosis factor receptors in human myocardium. (PubMed id 7664431)1, 9 Torre-Amione G....Mann D.L. (1995)
    504. TNF-alpha modulates the migratory response of mesench ymal stem cells to TRAIL. (PubMed id 20063037)1, 9 Corallini F....Zauli G. (2010)
    505. Adipophilin affects the expression of TNF-alpha, MCP- 1, and IL-6 in THP-1 macrophages. (PubMed id 19851831)1, 9 Chen F.L....Hu R.M. (2010)
    506. Association between polymorphisms in human tumor necr osis factor-alpha (--308) and -beta (252) genes and development of gestational diabetes mellitus. (PubMed id 20189261)1, 9 Montazeri S....Radhakrishnan A.K. (2010)
    507. Genetic variation in chromosomal translocation breakp oint and immune function genes and risk of non-Hodgkin lymphoma. (PubMed id 20087644)1, 9 Fernberg P....EkstrAPm Smedby K. (2010)
    508. Genetic association of Toll-like-receptor 4 and tumor necrosis factor-alpha polymorphisms with Plasmodium falciparum blood infection levels. (PubMed id 20307689)1, 9 Basu M....Sengupta S. (2010)
    509. Insulin resistance in hyperthyroidism: the role of IL 6 and TNF alpha. (PubMed id 19837795)1, 9 Mitrou P....Dimitriadis G. (2010)
    510. Association of Interleukin-10, Interferon-gamma, Tran sforming Growth Factor-beta, and Tumor Necrosis Factor-alpha Gene Polymorphisms With Long-Term Kidney Allograft Survival. (PubMed id 20404426)1, 9 Omrani M.D....Ahmadpoor P. (2010)
    511. [Relationship between the level of serum TNF-alpha of patients with chronic hepatitis C and treatment with interferon-alpha and the influencing factors] (PubMed id 20104757)1, 9 Ren Y....Li J. (2009)
    512. The NRAMPI, VDR and TNF-alpha gene polymorphisms in I ranian tuberculosis patients: the study on host susceptibility. (PubMed id 20231985)1, 9 Merza M....Hoffner S. (2009)
    513. Proinflammatory tissue response and recovery of adipo kines during 4 days of subcutaneous large-pore microdialysis. (PubMed id 19328242)1, 9 Clausen T.S....Stallknecht B. (2009)
    514. Tumor necrosis factor-alpha levels in HIV-1 seroposit ive injecting drug users. (PubMed id 19347588)1, 9 Ownby R.L....Kumar M. (2009)
    515. Variation in the Lymphotoxin-alpha/Tumor Necrosis Factor Locus Modifies Risk of Erythema Nodosum in Sarcoidosis. (PubMed id 19225544)1, 9 McDougal K.E....Cutting G.R. (2009)
    516. The role of tumor necrosis factor (TNF)-alpha and TNF receptor polymorphisms in susceptibility to ankylosing spondylitis. (PubMed id 19772798)1, 9 Chatzikyriakidou A....Drosos A.A. (2009)
    517. [Rebamipide inhibited expression of TLR4 and TNF-alph a release in pulmonary epithelial cell line A549 induced by lipopolysaccharide] (PubMed id 19483297)1, 9 Wen X....Zhou X. (2009)
    518. Up-regulated renal expression of TNF-alpha signalling adapter proteins in lupus glomerulonephritis. (PubMed id 19151112)1, 9 Zhu L....Yu X. (2009)
    519. Synergism between tumor necrosis factor alpha and interleukin-17 to induce IL-23 p19 expression in fibroblast-like synoviocytes. (PubMed id 19201028)1, 9 Goldberg M....Katz Y. (2009)
    520. Association of polymorphisms in Tumor Necrosis Factor Alpha and Beta genes with increased risk for oral cancer. (PubMed id 19528505)1, 9 Yapijakis C....Vairaktaris E. (2009)
    521. Long-range linkage on chromosome 6p of VEGF, FKBP5, HLA and TNF alleles associated with transplant rejection. (PubMed id 19233472)1, 9 Chen Y....Hutchinson I.V. (2009)
    522. Histo- and immunocytochemical detection of inducible NOS and TNF-alpha in the locus coeruleus of human opiate addicts. (PubMed id 19038328)1, 9 Dyuizen I. and Lamash N.E. (2009)
    523. Pleural tuberculosis in patients with early HIV infection is associated with increased TNF-alpha expression and necrosis in granulomas. (PubMed id 19156215)1, 9 Bezuidenhout J....Walzl G. (2009)
    524. [Relationship among TNF-alpha gene promoter -308 site polymorphism, the levels of maternal serum TNF-alpha, and the mRNA expression placental TNF-alpha in preterm labor] (PubMed id 19292050)1, 9 Pu J. and Zeng W.Y. (2009)
    525. Joint effect of obesity and TNFA variability on asthma: two international cohort studies. (PubMed id 19196817)1, 9 Castro-Giner F....Probst-Hensch N.M. (2009)
    526. [Effect of TNF-alpha gene polymorphism on outcome of thalidomide-based regimens for multiple myeloma] (PubMed id 19954656)1, 9 DU J....Hou J. (2009)
    527. Association of gastric disease with polymorphisms in the inflammatory-related genes IL-1B, IL-1RN, IL-10, TNF and TLR4. (PubMed id 19295440)1, 9 Murphy G....O'Sullivan M. (2009)
    528. Alterations of the CD4(+), CD8 (+) T cell subsets, interleukins-1beta, IL-10, IL-17, tumor necrosis factor-alpha and soluble intercellular adhesion molecule-1 in rheumatoid arthritis and osteoarthritis: preliminary observations. (PubMed id 18392953)1, 9 Hussein M.R....Backer E.A. (2008)
    529. Tumor necrosis factor gene polymorphisms in Turkish patients with sarcoidosis. (PubMed id 18451575)1, 9 Seyhan E.C....Issever H. (2008)
    530. Influence of Functional Interleukin 10/Tumor Necrosis Factor-alpha Polymorphisms on Interferon-alpha, IL-10, and Regulatory T Cell Population in Patients with Systemic Lupus Erythematosus Receiving Antimalarial Treatment. (PubMed id 18597405)1, 9 Lopez P....Suarez A. (2008)
    531. [Determination and clinical implication of leukotriene B(4) and tumor necrosis factor-alpha in condensate of exhaled breath of chronic obstructive pulmonary disease patients] (PubMed id 18549718)1, 9 Chen J.L....Tao G.H. (2008)
    532. Role of TNF-alpha and extracellular ATP in THP-1 cell activation following allergen exposure. (PubMed id 18303186)1, 9 Miyazawa M....Nishiyama N. (2008)
    533. Cytokine gene polymorphism in kidney transplantation--impact of TGF-beta 1, TNF-alpha and IL-6 on graft outcome. (PubMed id 18158121)1, 9 Nikolova P.N....Naumova E.J. (2008)
    534. Tumor necrosis factor-alpha up-regulates the expression of CCL2 and adhesion molecules of human proximal tubular epithelial cells through MAPK signaling pathways. (PubMed id 18656701)1, 9 Ho A.W....Lam C.W. (2008)
    535. Combined effect of tumour necrosis factor-alpha and interleukin-13 polymorphisms on bronchial hyperresponsiveness in Korean children with asthma. (PubMed id 18341619)1, 9 Kim H.B....Hong S.J. (2008)
    536. Correlation between omental TNF-alpha protein and plasma PAI-1 in obesity subjects. (PubMed id 17698217)1, 9 Cao Y.L....Zhang J. (2008)
    537. Moraxella catarrhalis lipooligosaccharide selectively upregulates ICAM-1 expression on human monocytes and stimulates adjacent naive monocytes to produce TNF-alpha through cellular cross-talk. (PubMed id 18363879)1, 9 Xie H. and Gu X.X. (2008)
    538. A single tumour necrosis factor haplotype influences the response to adalimumab in rheumatoid arthritis. (PubMed id 17673491)1, 9 Miceli-Richard C....Mariette X. (2008)
    539. Polymorphisms of tumor-necrosis factor-alpha - 308 and lymphotoxin-alpha + 250: possible modulation of susceptibility to apoptosis in chronic lymphocytic leukemia and non-Hodgkin lymphoma mononuclear cells. (PubMed id 19021060)1, 9 Jevtovic-Stoimenov T....Pavlovic S. (2008)
    540. Associations between tumor necrosis factor-alpha and lymphotoxin-alpha polymorphisms and idiopathic recurrent miscarriage. (PubMed id 18299433)1, 9 Zammiti W....Mahjoub T. (2008)
    541. Tumor necrosis factor-alpha and Interleukin-10 gene promoter polymorphisms in Turkish rheumatoid arthritis patients. (PubMed id 18427872)1, 9 Ates O....Topal-Sarikaya A. (2008)
    542. Tumor necrosis factor - alpha and transforming growth factor - beta1 polymorphisms in bronchial asthma. (PubMed id 18711258)1, 9 Kumar A....Sehajpal P.K. (2008)
    543. TNFalpha in patients with end-stage heart failure on medical therapy or supported by a left ventricular assist device. (PubMed id 18346639)1, 9 Bruggink A.H....De Weger R.A. (2008)
    544. [Association between susceptibility of endometriosis and the gene polymorphism of tumor necrosis factor] (PubMed id 18754435)1, 9 Lu D.H....Deng L. (2008)
    545. TNF-alpha represses connexin43 expression in HaCat keratinocytes via activation of JNK signaling. (PubMed id 18297686)1, 9 Tacheau C....Verrecchia F. (2008)
    546. Interleukin-1beta and tumour necrosis factor-alpha impede neutral lipid turnover in macrophage-derived foam cells. (PubMed id 19032770)1, 9 Persson J....Lindholm M.W. (2008)
    547. Activation of keratinocyte protein kinase C zeta in psoriasis plaques. (PubMed id 18385757)1, 9 Zhao Y....Gaspari A.A. (2008)
    548. Suppression of lipopolysaccharide-stimulated tumor necrosis factor-alpha production by adiponectin is mediated by transcriptional and post-transcriptional mechanisms. (PubMed id 18678874)1, 9 Park P.H....Nagy L.E. (2008)
    549. [Influence of G308A polymorphism of tumor necrosis factor alpha gene on insulin resistance in obese patients after weight loss] (PubMed id 17927932)1, 9 de Luis D.A....Romero E. (2007)
    550. Polymorphisms in TGFbeta and TNFalpha are associated with the myelodysplastic syndrome phenotype. (PubMed id 18081437)1, 9 Powers M.P....Chang C.C. (2007)
    551. Effect of tumor necrosis factor-alpha gene polymorphism on peri-implant bone loss following prosthetic reconstruction. (PubMed id 17356374)1, 9 Cury P.R....de Araujo N.S. (2007)
    552. Role of IL-6, TNF-A and LT-A variants in the modulation of the clinical expression of plaque-induced gingivitis. (PubMed id 17953695)1, 9 Scapoli C....Trombelli L. (2007)
    553. Association of TGFbeta1, TNFalpha, CCR2 and CCR5 gene polymorphisms in type-2 diabetes and renal insufficiency among Asian Indians. (PubMed id 17428349)1, 9 Prasad P....Thelma B.K. (2007)
    554. Clinical and genetic risk factors for pneumonia in systemic lupus erythematosus. (PubMed id 17665457)1, 9 Kinder B.W....Criswell L.A. (2007)
    555. Stimulation of the peroxisome proliferator-activated receptor gamma (PPAR gamma) and the expression of selected blood monocyte cytokine genes in diabetic macroangiopathy. (PubMed id 17141246)1, 9 Adamiec R....Sadakierska-Chudy A. (2007)
    556. [Selection of one of the TNF blockers; infliximab and etanercept] (PubMed id 17642244)7, 9 Mimura T. (2007)
    557. TNF-alpha gene promoter -238G>A and -308G>A polymorphisms alter risk of psoriasis vulgaris: a meta-analysis. (PubMed id 17446901)1, 9 Li C....Gao T. (2007)
    558. Associations of promoter region polymorphisms in the tumour necrosis factor-alpha gene and early-onset psoriasis vulgaris in a northern Polish population. (PubMed id 17553030)1, 9 Nedoszytko B....Roszkiewicz J. (2007)
    559. Macrophage colony stimulating factor expression in human cardiac cells is upregulated by tumor necrosis factor-alpha via an NF-kappaB dependent mechanism. (PubMed id 17922812)1, 9 Hohensinner P.J....Wojta J. (2007)
    560. Dopamine induces TNFalpha and TNF-R1 expression in SH-SY5Y human neuroblastoma cells. (PubMed id 17921876)1, 9 Gomez-Santos C....Ambrosio S. (2007)
    561. Regulation of p21Waf1 expression and TNFalpha biosynthesis by glutathione modulators in PMA induced-THP1 differentiation: involvement of JNK and ERK pathways. (PubMed id 17920036)1, 9 Debbas V....Monteiro H.P. (2007)
    562. Predictive value of cytokine gene polymorphisms for the development of end-stage renal disease. (PubMed id 17173255)1, 9 Babel N....Reinke P. (2006)
    563. Cytokine gene polymorphisms in Turkish patients with inflammatory bowel disease. (PubMed id 16638698)1, 9 Celik Y....Bozdayi A.M. (2006)
    564. TNF-alpha and IFN-alpha enhance influenza-A-virus-induced chemokine gene expression in human A549 lung epithelial cells. (PubMed id 16253303)1, 9 Veckman V....Julkunen I. (2006)
    565. TNF-alpha blockade down-regulates the CD40/CD40L pathway in the mucosal microcirculation: a novel anti-inflammatory mechanism of infliximab in Crohn's disease. (PubMed id 16456024)7, 9 Danese S....Fiocchi C. (2006)
    566. Polymorphisms in the TNF-alpha promoter and variability in the granulomatous response in patients with Crohn's disease. (PubMed id 16641217)1, 9 Dalal I....Levine A. (2006)
    567. JAB1 determines the response of rheumatoid arthritis synovial fibroblasts to tumor necrosis factor-alpha. (PubMed id 16936264)1, 9 Wang J....Zhang H.G. (2006)
    568. Association of TNF haplotypes with asthma, serum IgE levels, and correlation with serum TNF-alpha levels. (PubMed id 16728705)1, 9 Sharma S....Ghosh B. (2006)
    569. Chloroquine treatment influences proinflammatory cytokine levels in systemic lupus erythematosus patients. (PubMed id 16761500)7, 9 Wozniacka A....Sysa-Jedrzejowska A. (2006)
    570. Combined polymorphisms of tumour necrosis factor alpha and interleukin-10 genes in patients with alcoholic hepatitis. (PubMed id 16702858)1, 9 Richardet J.P....Bories P.N. (2006)
    571. Novel anti-inflammatory role for glycogen synthase kinase-3beta in the inhibition of tumor necrosis factor-alpha- and interleukin-1beta-induced inflammatory gene expression. (PubMed id 16601113)1, 9 Vines A....Pillarisetti S. (2006)
    572. Prevalence of two tumor necrosis factor gene polymorphisms in premature infants with early onset sepsis. (PubMed id 17108674)1, 9 Schueller A.C....Stuber F. (2006)
    573. Expression of tumor necrosis factor alpha and its receptors during cellular differentiation. (PubMed id 16580225)1, 9 Schling P....Schmitz G. (2006)
    574. Tumour necrosis factor (TNF)alpha -308 G/G promoter polymorphism and TNFalpha levels correlate with a better response to adalimumab in patients with rheumatoid arthritis. (PubMed id 17343250)1, 9 Cuchacovich M....Aguillon J.C. (2006)
    575. Tumor necrosis factor and vascular endothelial growth factor induce endothelial integrin repertories, regulating endovascular differentiation and apoptosis in a human extravillous trophoblast cell line. (PubMed id 15788755)1, 9 Fukushima K....Nakano H. (2005)
    576. Expression of TNFalpha and its receptors R1 and R2 in human alveolar epithelial cells exposed to organic dust and the effects of 8-bromo-cAMP and protein kinase A modulation. (PubMed id 16134057)1, 9 Burvall K....Larsson K. (2005)
    577. The reciprocal association of adipocytokines with insulin resistance and C-reactive protein in clinically healthy men. (PubMed id 15798948)1, 9 Behre C.J....Hulthe J. (2005)
    578. Differential effects of tumor necrosis factor-alpha and CD40L on NF-kappaB inhibitory proteins IkappaBalpha, beta and epsilon and on the induction of the Jun amino-terminal kinase pathway in Ramos Burkitt lymphoma cells. (PubMed id 16464740)1, 9 Laskov R....Horwitz M.S. (2005)
    579. Genetic contribution of the tumour necrosis factor (TNF) B + 252*2/2 genotype, but not the TNFa,b microsatellite alleles, to systemic lupus erythematosus in Japanese patients. (PubMed id 15932622)1, 9 Takeuchi F....Tanimoto K. (2005)
    580. NOD2/CARD15 and TNFA, but not IL1B and IL1RN, are associated with Crohn's disease. (PubMed id 15803022)1, 9 Ferreira A.C....Tavarela-Veloso F. (2005)
    581. Cross-regulation of TNF and IFN-alpha in autoimmune diseases. (PubMed id 15728381)1, 9 Palucka A.K....Banchereau J. (2005)
    582. Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha. (PubMed id 15685549)1, 9 Mitoma H....Harada M. (2005)
    583. Extended haplotype in the tumor necrosis factor gene cluster is associated with asthma and asthma-related phenotypes. (PubMed id 15976383)1, 9 Randolph A.G....Weiss S.T. (2005)
    584. Cloning and characterization of a small-size peptide Zfra that regulates the cytotoxic function of tumor necrosis factor by interacting with JNK1. (PubMed id 15629131)1, 9 Hsu L.J....Chang N.S. (2005)
    585. Beyond insulin resistance in NASH: TNF-alpha or adiponectin? (PubMed id 15239085)1, 9 Hui J.M....George J. (2004)
    586. Insulin resistance is not due to persistently elevated serum tumor necrosis-alpha levels in small for gestational age, premature, or twin children. (PubMed id 15043686)1, 9 Jefferies C.A....Cutfield W.S. (2004)
    587. The effects of calcitriol therapy on serum interleukin-1, interleukin-6 and tumour necrosis factor-alpha concentrations in post-menopausal patients with osteoporosis. (PubMed id 15587751)1, 9 Inanir A....Mermerci B. (2004)
    588. UVB radiation-mediated expression of inducible nitric oxide synthase activity and the augmenting role of co-induced TNF-alpha in human skin endothelial cells. (PubMed id 15482484)1, 9 Suschek C.V....Kolb-Bachofen V. (2004)
    589. Susceptibility for ischemic stroke in Korean population is associated with polymorphisms of the interleukin-1 receptor antagonist and tumor necrosis factor-alpha genes, but not the interleukin-1beta gene. (PubMed id 15036607)1, 9 Lee B.C....Chung J.H. (2004)
    590. Tumour necrosis factor alpha polymorphisms are not involved in the development of steatosis in chronic hepatitis C. (PubMed id 15256977)1, 9 Sanchez-Munoz D....Nunez-Roldan A. (2004)
    591. Nickel and DNCB induce CCR7 expression on human dendritic cells through different signalling pathways: role of TNF-alpha and MAPK. (PubMed id 15304089)1, 9 Boisleve F....Pallardy M. (2004)
    592. Polymorphism in promoter region of IL10 gene is associated with rheumatoid arthritis in women. (PubMed id 14994383)1, 9 Padyukov L....Klareskog L. (2004)
    593. GM-CSF and TNF-alpha synergize to increase in vitro granuloma size of PBMC from humans induced by Schistosoma mansoni recombinant 28-kDa GST. (PubMed id 15388264)1, 9 Rezende C.M....Goes A.M. (2004)
    594. Association of tumor necrosis factor polymorphisms with asthma and serum total IgE. (PubMed id 14681301)1, 9 Shin H.D....Park C.S. (2004)
    595. Tumor necrosis factor-alpha allele lymphotoxin-alpha+250 is associated with the presence and severity of placental inflammation among preterm births. (PubMed id 15128916)1, 9 Kazzi S.N....Buhimschi I.A. (2004)
    596. Association of IL-1beta, IL-1ra, and TNF-alpha gene polymorphisms in childhood nephrotic syndrome. (PubMed id 14758530)1, 9 Kim S.D....Cho B.S. (2004)
    597. Polymorphisms within the tumor necrosis factor and lymphotoxin-alpha genes and endemic pemphigus foliaceus--are there any associations? (PubMed id 14617046)1, 9 Roxo V.M....Petzl-Erler M.L. (2003)
    598. Enhanced TNF alpha and oxidative stress in patients with heart failure: effect of TNF alpha on platelet O2- production. (PubMed id 12888880)1, 9 De Biase L....Violi F. (2003)
    599. Cytokine single nucleotide polymorphisms and intrarenal gene expression in chronic allograft nephropathy in children. (PubMed id 12787424)1, 9 Melk A....Von Schnakenburg C. (2003)
    600. Lack of association between the promoter polymorphisms at positions -308 and -238 of the tumor necrosis factor alpha gene and psoriasis vulgaris in Japanese patients. (PubMed id 14657629)1, 9 Tsunemi Y....Tamaki K. (2003)
    601. Involvement of Fas and TNF pathways in the induction of apoptosis of T cells by antithymocyte globulin. (PubMed id 12783210)1, 9 Dubey S. and Nityanand S. (2003)
    602. Intra-arterial tumor necrosis factor-alpha impairs endothelium-dependent vasodilatation and stimulates local tissue plasminogen activator release in humans. (PubMed id 12692009)1, 9 Chia S....Newby D.E. (2003)
    603. Tumor necrosis factor-alpha, lymphotoxin-alpha, and interleukin-10 gene polymorphisms and restenosis after coronary artery stenting. (PubMed id 14572794)1, 9 Koch W....Kastrati A. (2003)
    604. TNF and TNF receptor polymorphisms in Korean Behcet's disease patients. (PubMed id 12770792)1, 9 Lee E.B....Song Y.W. (2003)
    605. TNF-alpha and -beta gene polymorphisms in multiple sclerosis: a highly significant role for determinants in the first intron of the TNF-beta gene. (PubMed id 12568117)1, 9 Fernandes Filho J.A....Pandey J.P. (2002)
    606. The association between tumor necrosis factor, HLA-DR alleles, and IgE-mediated asthma in Taiwanese adolescents. (PubMed id 12169181)1, 9 Lin Y.C....Guo Y.L. (2002)
    607. Tumour necrosis factor-alpha polymorphism and the HLA-Cw*0602 allele in psoriatic arthritis. (PubMed id 12011375)1, 9 Al-Heresh A.M....McHugh N. (2002)
    608. Recurrent aphthous stomatitis and gene polymorphisms for the inflammatory markers TNF-alpha, TNF-beta and the vitamin D receptor: no association detected. (PubMed id 12477062)4, 9 Bazrafshani M.R....Thornhill M.H. (2002)
    609. Tumour necrosis factor-alpha, interleukin-2 soluble receptor and different inflammatory parameters in patients with rheumatoid arthritis. (PubMed id 12581498)1, 9 Frode T.S....Medeiros Y.S. (2002)
    610. Polymorphisms in or near tumour necrosis factor (TNF)-gene do not determine levels of endotoxin-induced TNF production. (PubMed id 11857057)1, 9 de Jong B.A....Huizinga T.W. (2002)
    611. Effect of thalidomide on the skeletal muscle in experimental heart failure. (PubMed id 12167383)7, 9 Vescovo G....Dalla Libera L. (2002)
    612. The pathophysiological influence of leptin and the tumor necrosis factor system on maternal insulin resistance: negative correlation with anthropometric parameters of neonates in gestational diabetes. (PubMed id 12626032)1, 9 Cseh K....Winkler G. (2002)
    613. Tumor necrosis factor system in insulin resistance in gestational diabetes. (PubMed id 11891016)1, 9 Winkler G....Karadi I. (2002)
    614. TNF-alpha--accelerated apoptosis abrogates ANCA-mediated neutrophil respiratory burst by a caspase-dependent mechanism. (PubMed id 11849390)1, 9 Kettritz R....Haller H. (2002)
    615. Critical role of tumor necrosis factor-alpha and NF-kappa B in interferon-gamma -induced CD40 expression in microglia/macrophages. (PubMed id 11830590)1, 9 Nguyen V.T. and Benveniste E.N. (2002)
    616. Influence of TNFalpha and LTalpha single nucleotide polymorphisms on susceptibility to and prognosis in cutaneous malignant melanoma in the British population. (PubMed id 11841484)1, 9 Howell W.M....Theaker J.M. (2002)
    617. Tumour necrosis factor-alpha promoter polymorphism in erythema nodosum. (PubMed id 11411907)1, 9 Labunski S....Kunz M. (2001)
    618. The gene polymorphism of tumor necrosis factor-beta, but not that of tumor necrosis factor-alpha, is associated with the prognosis of sarcoidosis. (PubMed id 11243953)1, 9 Yamaguchi E....Kawakami Y. (2001)
    619. Polymorphisms within the tumor necrosis factor locus and prevalence of coronary artery disease in middle-aged men. (PubMed id 11257271)1, 9 Keso T....Karhunen P.J. (2001)
    620. The G-308A variant of the Tumor Necrosis Factor-alpha (TNF-alpha) gene is not associated with obesity, insulin resistance and body fat distribution. (PubMed id 11570978)1, 9 Romeo S....Baroni M.G. (2001)
    621. Tumor necrosis factor alpha 5'-flanking region, tumor necrosis factor receptor II, and HLA-DRB1 polymorphisms in Japanese patients with rheumatoid arthritis. (PubMed id 10765919)4, 9 Shibue T....Tokunaga K. (2000)
    622. Role of tumor necrosis factor-alpha gene locus in obesity and obesity-associated hypertension in French Canadians. (PubMed id 10904006)4, 9 Pausova Z....Hamet P. (2000)
    623. Tumor necrosis factor-beta gene NcoI polymorphism decreases insulin resistance in Japanese men. (PubMed id 11092520)1, 9 Hayakawa T....Kobayashi K. (2000)
    624. The -238 and -308 G-->A polymorphisms of the tumor necrosis factor alpha gene promoter are not associated with features of the insulin resistance syndrome or altered birth weight in Danish Caucasians. (PubMed id 10770222)4, 9 Rasmussen S.K....Pedersen O. (2000)
    625. Pilot study assessing TNF gene polymorphism as a prognostic marker for disease progression in neonates with sepsis. (PubMed id 10782394)4, 9 Weitkamp J.H....Bartmann P. (2000)
    626. Lack of association between the -308 polymorphism of the tumor necrosis factor-alpha gene and the insulin resistance syndrome. (PubMed id 10916281)4, 9 da Sliva B....Lowe W.L. (2000)
    627. TNF-alpha inhibits HIV-1 replication in peripheral blood monocytes and alveolar macrophages by inducing the production of RANTES and decreasing C-C chemokine receptor 5 (CCR5) expression. (PubMed id 10490959)1, 9 Lane B.R....Coffey M.J. (1999)
    628. Prevalence of tumor necrosis factor-alpha and angiotensin converting enzyme polymorphisms in mild/moderate and fatal/near-fatal asthma. (PubMed id 10390412)4, 9 Chagani T....Sandford A.J. (1999)
    629. Severe malarial anemia and cerebral malaria are associated with different tumor necrosis factor promoter alleles. (PubMed id 9841857)4, 9 McGuire W....Kwiatkowski D. (1999)
    630. Association of polymorphisms within the tumour necrosis factor (TNF) genes and childhood asthma. (PubMed id 9645594)4, 9 Albuquerque R.V....Lesouef P.N. (1998)
    631. Tumor necrosis factor-alpha gene polymorphism in psoriasis. (PubMed id 9395887)4, 9 Arias A.I....Pandey J.P. (1997)
    632. Suppression of nephrin expression by TNF-alpha via in terfering with the cAMP-retinoic acid receptor pathway. (PubMed id 20237236)1, 9 Saito Y....Kitamura M. (2010)
    633. TNFalpha and TGF-beta1 influence IL-18-induced IFNgam ma production through regulation of IL-18 receptor and T-bet expression. (PubMed id 19879772)1, 9 Koutoulaki A....Wei X.Q. (2010)
    634. Possible involvements of nuclear factor-kappa B and a ctivator protein-1 in the tumor necrosis factor-alpha-induced upregulation of m atrix metalloproteinase-12 in human alveolar epithelial A549 cell line. (PubMed id 20051654)1, 9 Yu Y....Misawa M. (2010)
    635. [Impact of TNF-alpha gene polymorphism, development o f atherogenic dyslipidemia and risk of atherosclerosis] (PubMed id 20422754)1, 9 RoA-tenberg G.E....Serebriakova O.E. (2010)
    636. Selective inhibition of TNF-alpha or IL-1 beta does n ot affect E. coli-induced inflammation in human whole blood. (PubMed id 20334922)1, 9 Barratt-Due A....Mollnes T.E. (2010)
    637. Interleukin (IL)-1beta, IL-1 receptor antagonist, IL- 6, IL-8, IL-10, and tumor necrosis factor alpha gene polymorphisms in patients with febrile seizures. (PubMed id 20486195)1, 9 Chou I.C....Tsai F.J. (2010)
    638. The relationship between tumor necrosis factor-alpha, brain natriuretic peptide and atrial natriuretic peptide in patients with chro nic heart failure. (PubMed id 19155075)1, 9 Vaz PAcrez A....Rauchhaus M. (2010)
    639. The effect of the pro-inflammatory cytokine tumor nec rosis factor-alpha on human joint capsule myofibroblasts. (PubMed id 20064200)1, 9 Mattyasovszky S.G....Rommens P.M. (2010)
    640. Involvement of MAPKs and NF-kappaB in tumor necrosis factor alpha-induced vascular cell adhesion molecule 1 expression in human rheu matoid arthritis synovial fibroblasts. (PubMed id 20039412)1, 9 Luo S.F....Yang C.M. (2010)
    641. Upregulation of MMP-9 production by TNFalpha in kerat inocytes and its attenuation by vitamin D. (PubMed id 20020446)1, 9 Bahar-Shany K....Koren R. (2010)
    642. Circulating E-selectin and tumor necrosis factor-alpha in extraarticular involvement and joint disease activity in rheumatoid arthritis. (PubMed id 18726101)1, 9 Corona-Sanchez E.G....Gamez-Nava J.I. (2009)
    643. Structure-function relationship of tumor necrosis factor (TNF) and its receptor interaction based on 3D structural analysis of a fully active TNFR1-selective TNF mutant. (PubMed id 19084540)1, 9 Mukai Y....Tsutsumi Y. (2009)
    644. Measurement of tumor necrosis factor-alpha, leukotriene B4, and interleukin 8 in the exhaled breath condensate in patients with acute exacerbations of chronic obstructive pulmonary disease. (PubMed id 19436689)1, 9 Ko F.W....Hui D.S. (2009)
    645. Plasma concentrations of TNF-alpha and its soluble re ceptors sTNFR1 and sTNFR2 in patients with coronary artery disease. (PubMed id 19845893)1, 9 Safranow K....Chlubek D. (2009)
    646. Enhanced propensity of T lymphocytes in patients with systemic lupus erythematosus to apoptosis in the presence of tumour necrosis factor alpha. (PubMed id 19110660)1, 9 Habib H.M....Mageed R.A. (2009)
    647. Effect of hypoxia and exogenous IL-10 on the pro-infl ammatory cytokine TNF-alpha and the anti-angiogenic molecule soluble Flt-1 in p lacental villous explants. (PubMed id 19501525)1, 9 Royle C....Hennessy A. (2009)
    648. Tumor necrosis factor--alpha gene promoter polymorphi sms in Chinese patients with nonalcoholic fatty liver diseases. (PubMed id 19637776)1, 9 Hu Z.W....Tang X. (2009)
    649. Interleukin-1 receptor antagonist and tumour necrosis factor-alpha gene polymorphisms in Turkish patients with allergic contact derm atitis. (PubMed id 19706048)1, 9 Ertam I....Ozkinay F. (2009)
    650. The role of P38 MAPK and PKC in BLP induced TNF-alpha release, apoptosis, and NFkappaB activation in THP-1 monocyte cells. (PubMed id 18675993)1, 9 O'Sullivan A.W....Redmond H.P. (2009)
    651. Association of TNF-alpha gene polymorphisms with syst emic lupus erythematosus in Taiwanese patients. (PubMed id 19762398)1, 9 Lin Y.J....Tsai F.J. (2009)
    652. [Expression of interleukin-1beta and tumor necrosis factor-alpha in the synovium and synovial fluid of patients with Kashin-Beck disease and osteoarthritis] (PubMed id 19218098)1, 9 Sun Z.M....Zhang Y.G. (2009)
    653. Transforming growth factor beta1-mediated activation of the smooth muscle alpha-actin gene in human pulmonary myofibroblasts is inhibited by tumor necrosis factor-alpha via mitogen-activated protein kinase kinase 1-dependent induction of the Egr-1 transcriptional repressor. (PubMed id 19261809)1, 9 Liu X....Strauch A.R. (2009)
    654. Acute hyperinsulinemia raises plasma interleukin-6 in both nondiabetic and type 2 diabetes mellitus subjects, and this effect is inversely associated with body mass index. (PubMed id 19375766)1, 9 Ruge T....Eriksson J.W. (2009)
    655. Tumor necrosis factor polymorphisms and alcoholic liv er disease: a HuGE review and meta-analysis. (PubMed id 19755636)1, 9 Marcos M....Laso F.J. (2009)
    656. Serum concentrations of markers of TNFalpha and Fas-mediated pathways and renal function in nonproteinuric patients with type 1 diabetes. (PubMed id 19073786)1, 9 Niewczas M.A....Krolewski A.S. (2009)
    657. Tumor necrosis factor-alpha -308 genotypes influence inflammatory activity and TNF-alpha serum concentrations in children with juvenile idiopathic arthritis. (PubMed id 19208590)1, 9 MourALo A.F....Fonseca J.E. (2009)
    658. Variation in inflammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke. (PubMed id 17981284)1, 9 Bis J.C....Psaty B.M. (2008)
    659. HLA class I and II and TNF-alpha gene polymorphisms in sarcoidosis patients. (PubMed id 19023492)1, 9 Morais A....Tafulo S. (2008)
    660. Novel cardiovascular risk factors in premature coronary atherosclerosis associated with systemic lupus erythematosus. (PubMed id 18634156)1, 9 Rho Y.H....Stein C.M. (2008)
    661. TNF, IFNG, IL6, IL10 and TGFB1 gene polymorphisms in South and Southeast Brazil. (PubMed id 18680515)1, 9 Visentainer J.E....de Souza C.A. (2008)
    662. Comparing Type D personality and older age as correlates of tumor necrosis factor-alpha dysregulation in chronic heart failure. (PubMed id 18068948)1, 9 Denollet J....Conraads V.M. (2008)
    663. Angiotensin II receptor blocker inhibits tumour necrosis factor-alpha-induced cell damage in human renal proximal tubular epithelial cells. (PubMed id 18331441)1, 9 Kagawa T....Hashimoto K. (2008)
    664. Differential association of tumour necrosis factor-alpha single nucleotide polymorphism (-308) with tuberculosis and bronchial asthma. (PubMed id 19004142)1, 9 Kumar V....Sehajpal P.K. (2008)
    665. Regulation of arterial-venous differences in tumor necrosis factor responsiveness of endothelial cells by anatomic context. (PubMed id 18292233)1, 9 Liu M....Pober J.S. (2008)
    666. Higher LPS-stimulated TNF-alpha mRNA levels in peripheral blood mononuclear cells from Chinese ankylosing spondylitis patients with -308(G/A) polymorphism in promoter region of tumor necrosis factor: association with distinct A33/B58/Cw10 haplotypes. (PubMed id 18719920)1, 9 Lu M.C....Lai N.S. (2008)
    667. Interleukin-10 (IL10) and tumor necrosis factor alpha (TNF) gene polymorphisms in Parkinson's disease patients. (PubMed id 18362084)1, 9 Bialecka M....Drozdzik M. (2008)
    668. Inflammatory system gene polymorphism and the risk of stroke: a case-control study in an Indian population. (PubMed id 18158110)1, 9 Banerjee I....Ganesh S. (2008)
    669. Tumor necrosis factor-alpha and mortality in heart failure: a community study. (PubMed id 18645056)1, 9 Dunlay S.M....Roger V.L. (2008)
    670. Tumor necrosis factor-alpha induces MMP-9 expression via p42/p44 MAPK, JNK, and nuclear factor-kappaB in A549 cells. (PubMed id 18336852)1, 9 Lin C.C....Yang C.M. (2008)
    671. Genetic polymorphisms of RANTES, IL1-A, MCP-1 and TNF-A genes in patients with prostate cancer. (PubMed id 19099590)1, 9 SA!enz-LA^pez P....Ruiz-Cabello F. (2008)
    672. [Isolation of Mycoplasma penetrans and detection of the levels of serum IL-6 and TNF-alpha in the blood of patients with antoimmune disease.] (PubMed id 18992196)1, 9 Wen X.S....Chen H.L. (2008)
    673. Plasma homocysteine is a determinant of tissue necrosis factor-alpha in hypertensive patients. (PubMed id 18093792)1, 9 Bogdanski P....Jakubowski H. (2008)
    674. Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals. (PubMed id 18838202)1, 9 Seal S....Deeg H.J. (2008)
    675. TNF and sTNFR1/2 plasma levels in ALS patients. (PubMed id 18083240)1, 9 Cereda C....Ceroni M. (2008)
    676. Cytokine Genes TNF, IL1A, IL1B, IL6, IL1RN and IL10, and childhood-onset mood disorders. (PubMed id 18832862)1, 9 Misener V.L....Barr C.L. (2008)
    677. Single nucleotide polymorphism in the tumor necrosis factor-alpha gene affects inflammatory bowel diseases risk. (PubMed id 18698679)1, 9 Ferguson L.R....Han D.Y. (2008)
    678. Human immunodeficiency virus infection alters tumor necrosis factor alpha production via Toll-like receptor-dependent pathways in alveolar macrophages and U1 cells. (PubMed id 18524817)1, 9 Nicol M.Q....Skolnik P.R. (2008)
    679. Vascular endothelial growth factor and tumor necrosis factor genes polymorphisms in Turkish patients with sarcoidosis. (PubMed id 18330749)1, 9 Seyhan E.C....Issever H. (2008)
    680. IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency. (PubMed id 17690329)1, 9 Demeo D.L....Silverman E.K. (2008)
    681. Tumor necrosis factor alpha drives cadherin 11 expression in rheumatoid inflammation. (PubMed id 18821672)1, 9 Vandooren B....Baeten D. (2008)
    682. PAI-1 gene 4G/5G polymorphism, cytokine levels and their relations with metabolic parameters in obese children. (PubMed id 18278185)1, 9 Kinik S.T....Atac F.B. (2008)
    683. Induction of macrophage secretion of tumor necrosis factor alpha through Fcgamma receptor IIa engagement by rheumatoid arthritis-specific autoantibodies to citrullinated proteins complexed with fibrinogen. (PubMed id 18311806)1, 9 Clavel C....Serre G. (2008)
    684. [Association of immune system gene polymorphisms with quantitative features which are pathogenetically important in chronic viral hepatitis] (PubMed id 18610832)1, 9 Goncharova I.A....pyzurev V.P. (2008)
    685. Tristetraprolin regulates TNF TNF-alpha mRNA stability via a proteasome dependent mechanism involving the combined action of the ERK and p38 pathways. (PubMed id 17606294)1, 9 Deleault K.M....Brooks S.A. (2008)
    686. Rheumatoid arthritis, periodontal disease and coronary artery disease. (PubMed id 17763921)1, 9 Abou-Raya S....Abuelkheir H. (2008)
    687. PPARalpha and PPARgamma effectively protect against HIV-induced inflammatory responses in brain endothelial cells. (PubMed id 18710415)1, 9 Huang W....Toborek M. (2008)
    688. Polymorphisms of the TNF, CD14, and HSPA1B genes in patients with acute alcohol-induced pancreatitis. (PubMed id 18580445)1, 9 Tukiainen E....Repo H. (2008)
    689. TNFA-308 in Two International Population-Based Cohorts Shows Increased Risk for Asthma. (PubMed id 18385169)1, 9 Castro-Giner F....Probst-Hensch N.M. (2008)
    690. Associations of proinflammatory cytokines with the risk of recurrent stroke. (PubMed id 18566306)1, 9 Welsh P....Woodward M. (2008)
    691. Nef and TNFalpha are coplayers that favor HIV-1 replication in monocytic cells and primary macrophages. (PubMed id 18336259)1, 9 Herbein G....Aggarwal B.B. (2008)
    692. A study on the TNF-alpha system in Caucasian Spanish patients with alcoholic liver disease. (PubMed id 17728075)1, 9 Auguet T....Richart C. (2008)
    693. HLA Dr-Dq haplotypes and the TNFA-308 polymorphism: associations with asthma and allergy. (PubMed id 17686102)1, 9 Munthe-Kaas M.C....Undlien D. (2007)
    694. Tumor necrosis factor alpha activates release of B lymphocyte stimulator by neutrophils infiltrating the rheumatoid joint. (PubMed id 17530706)1, 9 Assi L.K....Scheel-Toellner D. (2007)
    695. Lipopolysaccharide-binding protein plasma levels and liver TNF-alpha gene expression in obese patients: evidence for the potential role of endotoxin in the pathogenesis of non-alcoholic steatohepatitis. (PubMed id 18000721)1, 9 Ruiz A.G....Pons-Romero F. (2007)
    696. Tumor necrosis factor gene polymorphisms in Tunisian patients with Behcet's disease. (PubMed id 17349875)1, 9 Kamoun M....Hamzaoui K. (2007)
    697. Risk factors associated with non-alcoholic fatty liver disease in Chinese patients and the role of tumor necrosis factor-alpha. (PubMed id 18251167)1, 9 Chu C.J....Lee S.D. (2007)
    698. Tumor necrosis factor-alpha gene promoter polymorphism in patients with familial Mediterranean fever. (PubMed id 17057944)1, 9 Celebi Kobak A....Akarca U.S. (2007)
    699. IL1 and TNF gene polymorphisms in patients with juvenile idiopathic arthritis treated with TNF inhibitors. (PubMed id 17324969)1, 9 Cimaz R....Miossec P. (2007)
    700. Tumor necrosis factor alpha -238G>A genotype alters postprandial plasma levels of free fatty acids in obese individuals with type 2 diabetes mellitus. (PubMed id 17445540)1, 9 Fontaine-Bisson B....El-Sohemy A. (2007)
    701. Interferon-gamma and tumor necrosis factor-alpha sensitize primarily resistant human endometrial stromal cells to Fas-mediated apoptosis. (PubMed id 18003704)1, 9 Fluhr H....Licht P. (2007)
    702. Rosiglitazone attenuates NF-kappaB-dependent ICAM-1 and TNF-alpha production caused by homocysteine via inhibiting ERK1/2/p38MAPK activation. (PubMed id 17583675)1, 9 Bai Y.P....Zhang G.G. (2007)
    703. A novel gene variation of TNFalpha associated with ankylosing spondylitis: a reconfirmed study. (PubMed id 17472990)1, 9 Zhu X....Yang Z. (2007)
    704. Quantitative gene expression of cytokines in peripheral blood leukocytes stimulated in vitro: modulation by the anti-tumor nerosis factor-alpha antibody infliximab and comparison with the mucosal cytokine expression in patients with ulcerative colitis. (PubMed id 17900510)1, 9 Moriconi F....Ramadori G. (2007)
    705. Serum IL-1beta, IL-6, IL-8, and TNF-alpha levels in early diagnosis and management of neonatal sepsis. (PubMed id 18274637)1, 9 Kurt A.N....Yilmaz E. (2007)
    706. Insulin and adiponectin inhibit the TNFalpha-induced ADMA accumulation in human endothelial cells: the role of DDAH. (PubMed id 17141242)1, 9 Eid H.M....Seljeflot I. (2007)
    707. Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media. (PubMed id 17908769)1, 9 Emonts M....Sanders E.A. (2007)
    708. 15-Deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) mediates repression of TNF-alpha by decreasing levels of acetylated histone H3 and H4 at its promoter. (PubMed id 17532302)1, 9 Engdahl R....Daly J.M. (2007)
    709. The significance of tumor necrosis factor-alpha in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment. (PubMed id 16930761)1, 9 Chen H....Jia W. (2007)
    710. Parental smoking modifies the relation between genetic variation in tumor necrosis factor-alpha (TNF) and childhood asthma. (PubMed id 17450233)1, 9 Wu H....London S.J. (2007)
    711. Expression of matrix metalloproteinase-1 and tumor necrosis factor-alpha in ulcerative colitis. (PubMed id 17990358)1, 9 Wang Y.D. and Mao J.W. (2007)
    712. Polymorphisms of tumor necrosis factor-alpha, interleukin-10, cytochrome P450 3A5 and ABCB1 in Chinese liver transplant patients treated with immunosuppressant tacrolimus. (PubMed id 17568575)1, 9 Li D....Zhang G.L. (2007)
    713. Association of TNF-alpha gene promoter C-857T polymorphism with higher serum LDL cholesterol levels and carotid plaque formation in Japanese patients with type 2 diabetes. (PubMed id 17347550)1, 9 Yamashina M....Satoh J. (2007)
    714. Polymorphisms in the IL-4, IL-4 receptor alpha chain, TNF-alpha, and lymphotoxin-alpha genes and risk of asthma in Hong Kong Chinese adults. (PubMed id 17536219)1, 9 Mak J.C....Chan-Yeung M. (2007)
    715. TNF-alpha, TNF-beta and IL-4 gene polymorphisms in Iranian patients with multiple sclerosis. (PubMed id 17295710)1, 9 Kamali-Sarvestani E....Gharesi-Fard B. (2007)
    716. Association between human African trypanosomiasis and the IL6 gene in a Congolese population. (PubMed id 16720107)1, 9 Courtin D....Garcia A. (2007)
    717. Interferon-gamma and bacterial lipopolysaccharide act synergistically on human neutrophils enhancing interleukin-8, interleukin-1beta, tumor necrosis factor-alpha, and interleukin-12 p70 secretion and phagocytosis via upregulation of toll-like receptor 4. (PubMed id 17304101)1, 9 Pearl-Yafe M....Shalit I. (2007)
    718. LPS-stimulated production of TNF-alpha by peripheral blood monocytes in patients with Behcet's disease. (PubMed id 16897113)1, 9 Slobodin G....Toubi E. (2007)
    719. Interleukin-10 and Tumor Necrosis Factor-alpha Gene Polymorphisms in Tuberculosis. (PubMed id 18071881)1, 9 Ates O....Topal-Sarikaya A. (2007)
    720. Role of genetic polymorphisms in ACE and TNF-alpha gene in sarcoidosis: a meta-analysis. (PubMed id 17768594)1, 9 Medica I....Peterlin B. (2007)
    721. Association between polymorphism of tumour necrosis factor alpha-308 gene promoter and asthma: a meta-analysis. (PubMed id 16517578)1, 9 Gao J....Gao X. (2006)
    722. [Association between tumor necrosis factor-alpha promoter polymorphisms and type 2 diabetes and obesity in Chilean elderly women] (PubMed id 17167711)1, 9 Santos M J.L....Albala B C. (2006)
    723. An association between asthma and TNF-308G/A polymorphism: meta-analysis. (PubMed id 16865291)1, 9 Aoki T....Noguchi E. (2006)
    724. The effects of genetic polymorphisms of IL-1 and TNF-A on Helicobacter pylori-induced gastroduodenal diseases in Korea. (PubMed id 16579840)1, 9 Kim N....Song I.S. (2006)
    725. Associations of tumour necrosis factor alpha promoter polymorphisms at position -308 and -238 with clinical characteristics of chronic hepatitis C. (PubMed id 17052277)1, 9 Dai C.Y....Yu M.L. (2006)
    726. Tumor necrosis factor alpha promoter polymorphisms in patients with juvenile idiopathic arthritis. (PubMed id 16539828)1, 9 Schmeling H....Horneff G. (2006)
    727. [Association among serous and cerebrospinal fluid TNF-alpha level, gene polymorphisms of TNF-alpha and multiple sclerosis in Han nationality of southern China] (PubMed id 17160953)1, 9 Dong Y.X....Lin P.Y. (2006)
    728. Association of-238G/A and -857C/T polymorphisms of tumor necrosis factor-alpha gene promoter region with outcomes of hepatitis B virus infection. (PubMed id 16827185)1, 9 Li H.Q....Li H. (2006)
    729. TNFalpha induces chromosomal abnormalities independent of ROS through IKK, JNK, p38 and caspase pathways. (PubMed id 16723255)1, 9 Higashimoto T....Zandi E. (2006)
    730. Association of TNF-alpha, TNF-beta, IFN-gamma and IL-1Ra gene polymorphisms with Graves' disease in the Thai population. (PubMed id 17348243)1, 9 Nakkuntod J....Hirankarn N. (2006)
    731. Inhibition of apolipoprotein AI gene expression by tumor necrosis factor alpha: roles for MEK/ERK and JNK signaling. (PubMed id 16475830)1, 9 Beers A....Mooradian A.D. (2006)
    732. Tumor necrosis factor-alpha differentially modulates CD44 expression in ovarian cancer cells. (PubMed id 16908592)1, 9 Muthukumaran N....Rodriguez-Rodriguez L. (2006)
    733. Interleukin -1beta (IL-1 beta), interleukin 6 (IL-6) and tumor necrosis factor (TNF) in plasma and pleural fluid of pneumonia, lung cancer and tuberculous pleuritis. (PubMed id 18088554)1, 9 Ilonidis G....Anogianakis G. (2006)
    734. Association of TNF-alpha genetic polymorphism with HLA DPB1*0301. (PubMed id 17014432)1, 9 Kim S.H....Park H.S. (2006)
    735. Tumor necrosis factor-alpha and interleukin-1beta regulate interleukin-8 expression in third trimester decidual cells: implications for the genesis of chorioamnionitis. (PubMed id 17003486)1, 9 Lockwood C.J....Schatz F. (2006)
    736. Analysis of linkage between lymphotoxin alpha haplotype and polymorphisms in 5'-flanking region of tumor necrosis factor alpha gene associated with efficacy of infliximab for Crohn's disease patients. (PubMed id 17049565)1, 9 Ozeki T....Yamada Y. (2006)
    737. Lack of association of tumor necrosis factor-alpha gene polymorphisms with disease susceptibility and severity in Behcet's disease. (PubMed id 15875188)1, 9 Ates A....Duman M. (2006)
    738. Tumor necrosis factor-alpha down-regulates human Cu/Zn superoxide dismutase 1 promoter via JNK/AP-1 signaling pathway. (PubMed id 16895791)1, 9 Afonso V....Lomri A. (2006)
    739. [The -308 and -238 Polymorphisms of the TNF-alpha Promoter Gene in Type 2 Diabetes Mellitus.] (PubMed id 18156701)1, 9 Kim H.R....Park A.J. (2006)
    740. Changes of tumor necrosis factor, surfactant protein A, and phospholipids in bronchoalveolar lavage fluid in the development and progression of coal workers' pneumoconiosis. (PubMed id 16827183)1, 9 Xing J.C....Bruch J. (2006)
    741. Tumor necrosis factor alpha is associated with insulin-mediated suppression of free fatty acids and net lipid oxidation in HIV-infected patients with lipodystrophy. (PubMed id 16423623)1, 9 Haugaard S.B....Iversen J. (2006)
    742. Transcriptional regulation of the osterix (Osx, Sp7) promoter by tumor necrosis factor identifies disparate effects of mitogen-activated protein kinase and NF kappa B pathways. (PubMed id 16410254)1, 9 Lu X....Nanes M.S. (2006)
    743. Cytokine gene polymorphisms in bullous pemphigoid in a Chinese population. (PubMed id 16403098)1, 9 Chang Y.T....Tsai S.F. (2006)
    744. [Tumor necrosis factor alpha (TNF-alpha) gene G-308A polymorphism relationship to insulin resistance and lipid abnormalities in children with obesity] (PubMed id 17020650)1, 9 Pyrzak B....Rymkiewicz-Kluczynska B. (2006)
    745. Insufficient endogenous control of tumor necrosis factor-alpha contributes to temporomandibular joint pain and tissue destruction in rheumatoid arthritis. (PubMed id 16960936)1, 9 Alstergren P. and Kopp S. (2006)
    746. Could single-nucleotide polymorphisms (SNPs) affecting the tumour necrosis factor promoter be considered as part of rheumatoid arthritis evolution? (PubMed id 16446172)1, 9 AguillA^n J.C....Cuchacovich M. (2006)
    747. Associations of tumor necrosis factor G-308A with childhood asthma and wheezing. (PubMed id 16456144)1, 9 Li Y.F....Gilliland F.D. (2006)
    748. Association of TNFd and IL-10 polymorphisms with mortality in unrelated hematopoietic stem cell transplantation. (PubMed id 16699452)1, 9 Bettens F....Tiercy J.M. (2006)
    749. Clinical importance of transforming growth factor-beta but not of tumor necrosis factor-alpha gene polymorphisms in patients with the myelodysplastic syndrome belonging to the refractory anemia subtype. (PubMed id 15860935)1, 9 Balog A....Mandi Y. (2005)
    750. Interleukin-4 suppresses the enhancement of ceramide synthesis and cutaneous permeability barrier functions induced by tumor necrosis factor-alpha and interferon-gamma in human epidermis. (PubMed id 15816837)1, 9 Hatano Y....Katagiri K. (2005)
    751. Tumour necrosis factor activates the mitogen-activated protein kinases p38alpha and ERK in the synovial membrane in vivo. (PubMed id 16207331)1, 9 Gortz B....Schett G. (2005)
    752. The influence of a polymorphism at position -857 of the tumour necrosis factor alpha gene on clinical response to etanercept therapy in rheumatoid arthritis. (PubMed id 15695296)1, 9 Kang C.P....Bae S.C. (2005)
    753. TNFalpha and IL10 SNPs act together to predict disease behaviour in Crohn's disease. (PubMed id 15937090)1, 9 Fowler E.V....Radford-Smith G.L. (2005)
    754. Association of tumour necrosis factor-alpha, lymphotoxin-alpha and HLA-DRB1 gene polymorphisms with Lofgren's syndrome in Czech patients with sarcoidosis. (PubMed id 15713215)1, 9 Mrazek F....Petrek M. (2005)
    755. Adiponectin induces TNF-alpha and IL-6 in macrophages and promotes tolerance to itself and other pro-inflammatory stimuli. (PubMed id 16115611)1, 9 Tsatsanis C....Margioris A.N. (2005)
    756. The association of the carrier state of the tumor necrosis factor-alpha (TNFalpha) -308A allele with the duration of oxygen supplementation in preterm neonates. (PubMed id 15809210)1, 9 Bokodi G....Vasarhelyi B. (2005)
    757. Inflammatory gene polymorphisms influence risk of postoperative morbidity after lung resection. (PubMed id 15854959)1, 9 Shaw A.D....Dickey B.F. (2005)
    758. TRAF-dependent association of protein kinase Tpl2/COT1 (MAP3K8) with CD40. (PubMed id 15670770)1, 9 Chan H. and Reed J.C. (2005)
    759. Interleukin 1 receptor antagonist and tumor necrosis factor-alpha gene polymorphism in patients with end-stage renal failure. (PubMed id 15717635)1, 9 Shu K.H....Lee W.C. (2005)
    760. Correlation between a gene polymorphism of tumor necrosis factor and inflammatory bowel disease. (PubMed id 16246225)1, 9 Song Y....Fan D.M. (2005)
    761. TNF-alpha upregulates adenosine 2b (A2b) receptor expression and signaling in intestinal epithelial cells: a basis for A2bR overexpression in colitis. (PubMed id 16322943)1, 9 Kolachala V....Sitaraman S.V. (2005)
    762. Circulating tumor necrosis factor alpha is higher in non-obese, non-diabetic Mexican Americans compared to non-Hispanic white adults. (PubMed id 15784408)1, 9 Ho R.C....Melby C.L. (2005)
    763. Tumor necrosis factor-alpha microsatellite polymorphism association with rheumatoid arthritis in Indian patients. (PubMed id 16099338)1, 9 Agrawal C....Das H.R. (2005)
    764. Correlation between levels of tumour necrosis factor-alpha and levels of pH, glucose, and lactate dehydrogenase in parapneumonic effusions. (PubMed id 15667911)1, 9 Odeh M....Oliven A. (2005)
    765. Meta-analysis on the G-308A tumor necrosis factor alpha gene variant and phenotypes associated with the metabolic syndrome. (PubMed id 16421346)1, 9 Sookoian S.C....Pirola C.J. (2005)
    766. [The role of genetic polymorphisms within tumor necrosis factor promoter gene in non-Hodgkin's lymphomas] (PubMed id 16786763)1, 9 Juszczynski P....Warzocha K. (2005)
    767. Tumor necrosis factor-alpha plays an important role in restenosis development. (PubMed id 16319143)1, 9 Monraats P.S....Jukema J.W. (2005)
    768. Impact of cytokine gene polymorphism on cardiovascular risk in renal transplant recipients. (PubMed id 15910294)1, 9 Altun B....Turgan C. (2005)
    769. Extended haplotype analysis reveals an association of TNF polymorphisms with susceptibility to systemic lupus erythematosus beyond HLA-DR3. (PubMed id 16095006)1, 9 Schotte H....Schluter B. (2005)
    770. Relevance of IL10, TGFbeta1, TNFalpha, and IL4Ralpha gene polymorphisms in kidney transplantation: a collaborative transplant study report. (PubMed id 15367225)1, 9 Mytilineos J....Opelz G. (2004)
    771. Polymorphisms in the promoter region of tumor necrosis factor alpha (TNF-alpha) and the HLA-DRB1 locus in Mexican mestizo patients with ulcerative colitis. (PubMed id 15325795)1, 9 Yamamoto-Furusho J.K....Granados J. (2004)
    772. Melatonin promoted chemotaxins expression in lung epithelial cell stimulated with TNF-alpha. (PubMed id 15537425)1, 9 Luo F....Wang Z. (2004)
    773. Tumor necrosis factor, interleukin 11, and leukemia inhibitory factor produced by Langerhans cells in Langerhans cell histiocytosis. (PubMed id 15543003)1, 9 Andersson By U....Henter J.I. (2004)
    774. Sarcoidosis and granuloma genes: a family-based study in African-Americans. (PubMed id 15332393)1, 9 Rybicki B.A....Iannuzzi M.C. (2004)
    775. Are pANCA, ASCA, or cytokine gene polymorphisms associated with pouchitis? Long-term follow-up in 102 ulcerative colitis patients. (PubMed id 15056081)1, 9 Aisenberg J....Sachar D.B. (2004)
    776. Inhibition of human herpes simplex virus type 2 by interferon gamma and tumor necrosis factor alpha is mediated by indoleamine 2,3-dioxygenase. (PubMed id 15374002)1, 9 Adams O....Daubener W. (2004)
    777. Intracellular expression of pro-inflammatory cytokines (IL-1alpha, TNF-alpha, and IL-6) in chronic hepatitis C. (PubMed id 15638425)1, 9 Kasprzak A....Zabel M. (2004)
    778. Soluble TNF-R1, but not tumor necrosis factor alpha, predicts the 3-month mortality in patients with alcoholic hepatitis. (PubMed id 15288471)1, 9 Spahr L....Hadengue A. (2004)
    779. Tumor necrosis factor alpha is a key mediator of gut inflammation seen in amebic colitis in human intestine in the SCID mouse-human intestinal xenograft model of disease. (PubMed id 12933883)1, 9 Zhang Z....Stanley S.L. (2003)
    780. Induction of matrix metalloproteinase-13 gene expression by TNF-alpha is mediated by MAP kinases, AP-1, and NF-kappaB transcription factors in articular chondrocytes. (PubMed id 12878172)1, 9 Liacini A....Zafarullah M. (2003)
    781. Polymorphisms of tumor necrosis factor (TNF) alpha and beta genes in Korean patients with psoriasis. (PubMed id 12709814)1, 9 Kim T.G....Kim T.Y. (2003)
    782. Overexpression of tumor necrosis factor-alpha diminishes pulmonary fibrosis induced by bleomycin or transforming growth factor-beta. (PubMed id 12816730)1, 9 Fujita M....Mason R.J. (2003)
    783. IL-10 and TNF-alpha polymorphisms in a sample of Sicilian patients affected by tuberculosis: implication for ageing and life span expectancy. (PubMed id 12714269)1, 9 Scola L....Lio D. (2003)
    784. Intratesticular delivery of tumor necrosis factor-alpha and ceramide directly abrogates steroidogenic acute regulatory protein expression and Leydig cell steroidogenesis in adult rats. (PubMed id 12959973)1, 9 Morales V....Ruiz de Galarreta C.M. (2003)
    785. [Expression of tumor necrosis factor-alpha and nuclear factor-kappa B in childhood ulcerative colitis] (PubMed id 14731353)1, 9 Tang H.F....Ou B.Y. (2003)
    786. Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation. (PubMed id 12753742)1, 9 Legler D.F....Bron C. (2003)
    787. Increased expression of TNF-alpha, IL-6, and IL-8 in HALS: implications for reduced adiponectin expression and plasma levels. (PubMed id 12876073)1, 9 Lihn A.S....Andersen O. (2003)
    788. The inducibility of TNF-alpha production is different in the granulocytic and monocytic differentiated forms of wild type and CGD-mutant PLB-985 cells. (PubMed id 14636244)1, 9 Selmeczy Z....Vizi E.S. (2003)
    789. Mapping the HLA association in Behcet's disease: a role for tumor necrosis factor polymorphisms? (PubMed id 12632436)1, 9 Ahmad T....Jewell D.P. (2003)
    790. Variation in the TNF gene promoter and risk of osteolysis after total hip arthroplasty. (PubMed id 14606512)1, 9 Wilkinson J.M....Eastell R. (2003)
    791. Systemic inflammation, adipose tissue tumor necrosis factor, and leptin expression. (PubMed id 12690081)1, 9 Bullo M....Salas-Salvado J. (2003)
    792. Tumor necrosis factor genetic polymorphisms and response to antiviral therapy in patients with chronic hepatitis C. (PubMed id 11922568)1, 9 Rosen H.R....Chou S. (2002)
    793. Hyperoxia prolongs tumor necrosis factor-alpha-mediated activation of NF-kappaB: role of IkappaB kinase. (PubMed id 11954826)1, 9 Wong H.R....Shanley T.P. (2002)
    794. Correlation of maternal serum fetuin/alpha2-HS-glycoprotein concentration with maternal insulin resistance and anthropometric parameters of neonates in normal pregnancy and gestational diabetes. (PubMed id 12153747)1, 9 Kalabay L....Winkler G. (2002)
    795. Differential association of polymorphisms in the TNFalpha region with psoriatic arthritis but not psoriasis. (PubMed id 11830425)1, 9 Hohler T....Marker-Hermann E. (2002)
    796. How does infliximab work in rheumatoid arthritis? (PubMed id 12110154)7, 9 Maini R.N. and Feldmann M. (2002)
    797. The role of cytokines in activation of coagulation and fibrinolysis in dengue shock syndrome. (PubMed id 11858187)1, 9 Suharti C....van der Meer J.W. (2002)
    798. Increased bioactive TNF in human systemic lupus erythematosus: associations with cell death. (PubMed id 11958572)1, 9 Aringer M....Graninger W.B. (2002)
    799. Cerebrospinal fluid and serum protein levels of tumour necrosis factor-alpha (TNF-alpha) interleukin-6 (IL-6) and soluble interleukin-6 receptor (sIL-6R gp80) in multiple sclerosis patients. (PubMed id 12445803)1, 9 Vladic A....Simaga S. (2002)
    800. Interrelationship between serum lipid profile, serum hormones and other components of the metabolic syndrome. (PubMed id 12603009)1, 9 Garaulet M....Tebar F.J. (2002)
    801. [Tumor necrosis factor alpha HLA-DRB(1) gene polymorphism and genetic susceptibility to cirrhosis] (PubMed id 12654235)1, 9 Lin J....Liang K. (2002)
    802. The TNF alpha/G-308A polymorphism influences insulin sensitivity in offspring of patients with coronary heart disease: the European Atherosclerosis Research Study II. (PubMed id 11888514)1, 9 Nicaud V....Tiret L. (2002)
    803. Polymorphisms in the interleukin-10, tumor necrosis factor-alpha, and transforming growth factor-beta1 genes in chronic hepatitis C patients treated with interferon and ribavirin. (PubMed id 11830340)1, 9 Vidigal P.G....Zein N.N. (2002)
    804. [Significance of tumor necrosis factor-alpha gene polymorphism in patients with acute severe pancreatitis] (PubMed id 12609060)1, 9 Zhang D....Tang X. (2002)
    805. Tumor necrosis factor gene polymorphisms, leukocyte function, and sepsis susceptibility in blunt trauma patients. (PubMed id 12414751)1, 9 Majetschak M....Heesen M. (2002)
    806. Increased frequency of the uncommon tumor necrosis factor -857T allele in British and Dutch patients with sarcoidosis. (PubMed id 11956055)1, 9 Grutters J.C....Welsh K.I. (2002)
    807. Thalidomide and its analogues have distinct and opposing effects on TNF-alpha and TNFR2 during co-stimulation of both CD4(+) and CD8(+) T cells. (PubMed id 12296856)1, 9 Marriott J.B....Dalgleish A.G. (2002)
    808. IL-17 selectively down-regulates TNF-alpha-induced RANTES gene expression in human colonic subepithelial myofibroblasts. (PubMed id 12165487)1, 9 Andoh A....Fujiyama Y. (2002)
    809. Polymorphism of tumor necrosis factor in esophageal, gastric or colorectal carcinoma. (PubMed id 11379335)1, 9 Saito S....Nakao A. (2001)
    810. Tumor necrosis factor-alpha gene polymorphisms in children with multiple sclerosis. (PubMed id 11571703)1, 9 Anlar B....Yakut A. (2001)
    811. Pro-inflammatory and pro-oxidant properties of the HIV protein Tat in a microglial cell line: attenuation by 17 beta-estradiol. (PubMed id 11579140)1, 9 Bruce-Keller A.J....Nath A. (2001)
    812. Tumor necrosis factor-alpha promoter polymorphisms in Mexican patients with systemic lupus erythematosus (SLE). (PubMed id 11704801)4, 9 Zuniga J....Granados J. (2001)
    813. Tumor necrosis factor promoter polymorphisms in patients with rheumatoid arthritis in Taiwan. (PubMed id 11508580)1, 9 Yen J.H....Liu H.W. (2001)
    814. Major histocompatibility locus genetic markers of beryllium sensitization and disease. (PubMed id 11716174)1, 9 Saltini C....Tinelli C. (2001)
    815. TNF-alpha polymorphisms in multiple sclerosis: no association with -238 and -308 promoter alleles, but the microsatellite allele a11 is associated with the disease in French patients. (PubMed id 10773851)4, 9 Lucotte G....Mercier G. (2000)
    816. Interethnic studies of TNF polymorphisms confirm the likely presence of a second MHC susceptibility locus in ankylosing spondylitis. (PubMed id 11196671)1, 9 Milicic A....Brown M.A. (2000)
    817. A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells. (PubMed id 10748004)1, 9 Madge L.A. and Pober J.S. (2000)
    818. HIV type 1 nef gene inhibits tumor necrosis factor alpha-induced apoptosis and promotes cell proliferation through the action of MAPK and JNK in human glial cells. (PubMed id 11153078)1, 9 Robichaud G.A. and Poulin L. (2000)
    819. Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF. (PubMed id 10357816)7, 9 Grell M....Strasser A. (1999)
    820. The HIV-1 vpr protein acts as a negative regulator of apoptosis in a human lymphoblastoid T cell line: possible implications for the pathogenesis of AIDS. (PubMed id 9449720)1, 9 Conti L....Gessani S. (1998)
    821. Tumour necrosis factor c2 microsatellite allele is associated with the rate of HIV disease progression. (PubMed id 9084788)4, 9 Khoo S.H....Ollier W.E. (1997)
    822. Replication of human immunodeficiency virus-1 in primary human T cells is dependent on the autocrine secretion of tumor necrosis factor through the control of nuclear factor-kappa B activation. (PubMed id 9438495)1, 9 Munoz-Fernandez M.A....Fresno M. (1997)
    823. Interethnic differences in the association of tumor necrosis factor promoter polymorphisms with systemic lupus erythematosus. (PubMed id 8895148)4, 9 Rudwaleit M....Wordsworth P. (1996)
    824. Increased frequency of the uncommon allele of a tumour necrosis factor alpha gene polymorphism in rheumatoid arthritis and systemic lupus erythematosus. (PubMed id 7614782)4, 9 Danis V.A....Grennan D. (1995)
    825. Induction of interleukin-1 and tumor necrosis factor alpha in brain cultures by human immunodeficiency virus type 1. (PubMed id 1548758)1, 9 Merrill J.E....Chen I.S. (1992)
    826. Molecular cloning and expression of a receptor for human tumor necrosis factor. (PubMed id 2158863)1, 9 Schall T.J....Raab H. (1990)
    827. Cooperative induction of CXCL10 involves NADPH oxidas e: Implications for HIV dementia. (PubMed id 19941336)1, 9 Williams R....Buch S. (2010)
    828. Genetic susceptibility to different clinical forms of tuberculosis in the Peruvian population. (PubMed id 20188863)1, 9 Taype C.A....Shaw M.A. (2010)
    829. Polymorphisms in TNF and HSP-70 show a significant as sociation with gastric cancer and duodenal ulcer. (PubMed id 19626584)1, 9 Partida-RodrA-guez O....Perez-RodrA-guez M. (2010)
    830. Tumor necrosis factor alpha gene variants do not disp lay allelic imbalance in circulating myeloid cells. (PubMed id 20206339)1, 9 Wienzek S....Bein G. (2010)
    831. The RING domain of TRAF2 plays an essential role in t he inhibition of TNFalpha-induced cell death but not in the activation of NF-ka ppaB. (PubMed id 20064526)1, 9 Zhang L....Habelhah H. (2010)
    832. TLR activation pathways in HIV-1-exposed seronegative individuals. (PubMed id 20124101)1, 9 Biasin M....Clerici M. (2010)
    833. The role of tumor necrosis factor alpha G-308A polymo rphisms in the course of pulmonary sarcoidosis. (PubMed id 20070603)1, 9 Wijnen P.A....Drent M. (2010)
    834. Meta-analysis of TNF-alpha promoter - 238A/G polymorp hism and SLE susceptibility. (PubMed id 20166876)1, 9 Zou Y.F....Ye D.Q. (2010)
    835. Suppressing IL-32 in monocytes impairs the induction of the proinflammatory cytokines TNFalpha and IL-1beta. (PubMed id 19880327)1, 9 Hong J....Kim S. (2010)
    836. TNF activates a NF-kappaB-regulated cellular program in human CD45RA- regulatory T cells that modulates their suppressive function. (PubMed id 20181891)1, 9 Nagar M....Goldstein I. (2010)
    837. TNF-alpha and IL-10 gene polymorphisms show a weak as sociation with pemphigus vulgaris in the Slovak population. (PubMed id 19470040)1, 9 Javor J....Svecova D. (2010)
    838. Effects of UVA on TNF-alpha, IL-1beta, and IL-10 expression levels in human keratinocytes and intervention studies with an antioxida nt and a JNK inhibitor. (PubMed id 20070836)1, 9 An L....Liu Y. (2010)
    839. Impact of genomic risk factors on outcome after hemat opoietic stem cell transplantation for patients with chronic myeloid leukemia. (PubMed id 20305143)1, 9 Dickinson A.M....Gratwohl A. (2010)
    840. Effect of 1,25 dihydroxyvitamin D3 on intracellular IFN-gamma and TNF-alpha positive T cell subsets in pulmonary tuberculosis. (PubMed id 19091593)1, 9 Prabhu Anand S....Narayanan P.R. (2009)
    841. Investigation of TNFA 308G > A and TNFB 252G > A polymorphisms in genetic susceptibility to migraine. (PubMed id 20035431)1, 9 Ghosh J....Mittal B. (2009)
    842. Cardiotrophin-1 induces tumor necrosis factor alpha s ynthesis in human peripheral blood mononuclear cells. (PubMed id 20224758)1, 9 Fritzenwanger M....Figulla H.R. (2009)
    843. ELISpot analysis of LPS-stimulated leukocytes: human granulocytes selectively secrete IL-8, MIP-1beta and TNF-alpha. (PubMed id 19358850)1, 9 Smedman C....Paulie S. (2009)
    844. Etanercept impairs maturation of human monocyte-derived dendritic cells by inhibiting the autocrine TNFalpha-mediated signaling. (PubMed id 19301111)1, 9 Slobodin G....Toubi E. (2009)
    845. Cytokine gene polymorphisms in BehAset's disease and t heir association with clinical and laboratory findings. (PubMed id 19796538)1, 9 Dilek K....Oral H.B. (2009)
    846. Lack of association of TNF-alpha promoter polymorphis ms with ankylosing spondylitis: a meta-analysis. (PubMed id 19720680)1, 9 Lee Y.H. and Song G.G. (2009)
    847. Tumor necrosis factor-alpha is a common genetic risk factor for asthma, juvenile rheumatoid arthritis, and systemic lupus erythemato sus in a Mexican pediatric population. (PubMed id 19480843)1, 9 JimAcnez-Morales S....Orozco L. (2009)
    848. Decreased high-density lipoprotein cholesterol level is an independent correlate of circulating tumor necrosis factor-alpha in a gen eral population. (PubMed id 19645041)1, 9 Yamagishi S....Imaizumi T. (2009)
    849. Association of cytokine gene polymorphisms with psori asis in cases from the Nile Delta of Egypt. (PubMed id 19784523)1, 9 Settin A....Hassan T. (2009)
    850. Does the simultaneous tumor necrosis factor receptor 2, tumor necrosis factor promoter gene polymorphism represent a higher risk for alcoholic liver disease? (PubMed id 19212208)1, 9 Machado M.V....Cortez-Pinto H. (2009)
    851. Effect of desensitization in solid organ transplant recipients depends on some cytokines genes polymorphism. (PubMed id 19332120)1, 9 Lobashevsky A.L....Turrentine M.W. (2009)
    852. Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNFalpha-induced MEK/ERK signalling. (PubMed id 19144181)1, 9 Rockel J.S....Leask A. (2009)
    853. -308G>A and -1031T>C tumor necrosis factor gene polymorphisms in Tunisian patients with coronary artery disease. (PubMed id 19803813)1, 9 Ghazouani L....Mahjoub T. (2009)
    854. Silencing of TNF-alpha receptors coordinately suppres ses TNF-alpha expression through NF-kappaB activation blockade in THP-1 macroph age. (PubMed id 19683526)1, 9 Verma N....Das R.H. (2009)
    855. TNF-alpha gene polymorphisms in Iranian Azeri Turkish patients with Behcet's Disease. (PubMed id 19774383)1, 9 Bonyadi M....Dastgiri S. (2009)
    856. Inflammatory cytokine mRNA detection by real time PCR in chorioamniotic membranes from pregnant women with preterm premature rupture of membranes. (PubMed id 19272692)1, 9 Polettini J....Silva M.G. (2009)
    857. Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE II. (PubMed id 19267370)1, 9 Wang M.H....Platz E.A. (2009)
    858. JNK/AP-1 pathway is involved in tumor necrosis factor -alpha induced expression of vascular endothelial growth factor in MCF7 cells. (PubMed id 19553068)1, 9 Yin Y....Han X. (2009)
    859. Independent and additive interactive effects among tu mor necrosis factor-alpha polymorphisms, substance use habits, and chronic hepa titis B and hepatitis C virus infection on risk for hepatocellular carcinoma. (PubMed id 19910749)1, 9 Jeng J.E....Chang J.G. (2009)
    860. Tumor necrosis factor-{alpha} downregulates intestinal NHE8 expression by reducing basal promoter activity. (PubMed id 19109523)1, 9 Xu H....Ghishan F.K. (2009)
    861. TNF and LTA Gene, Allele, and Extended HLA Haplotype Associations with Severe Dengue Virus Infection in Ethnic Thais. (PubMed id 19392621)1, 9 Vejbaesya S....Stephens H.A. (2009)
    862. Involvement of TNF-alpha in abnormal adipocyte and muscle sortilin expression in obese mice and humans. (PubMed id 19219422)1, 9 Kaddai V....Cormont M. (2009)
    863. Isoflavone genistein protects human vascular endothelial cells against tumor necrosis factor-alpha-induced apoptosis through the p38beta mitogen-activated protein kinase. (PubMed id 19082897)1, 9 Si H. and Liu D. (2009)
    864. Analysis of inflammation- and atherosclerosis-related gene polymorphisms in branch retinal vein occlusion. (PubMed id 19347053)1, 9 Steinbrugger I....Weger M. (2009)
    865. TNF, LTA and TGFB1 genotype distributions among acute graft-vs-host disease subsets after HLA-matched unrelated hematopoietic stem cell transplantation: a pilot study. (PubMed id 19392797)1, 9 Shah R....Posch P.E. (2009)
    866. Lysosomal serine protease CLN2 regulates tumor necrosis factor-alpha-mediated apoptosis in a bid-dependent manner. (PubMed id 19246452)1, 9 Autefage H....Andrieu-Abadie N. (2009)
    867. Cytokine gene polymorphisms and BALF cytokine levels in interstitial lung diseases. (PubMed id 19117745)1, 9 Vasakova M....Striz I. (2009)
    868. Association of interferon-gamma and tumor necrosis factor alpha polymorphisms with susceptibility to vitiligo in Iranian patients. (PubMed id 18820938)1, 9 Namian A.M....Kamali-Sarvestani E. (2009)
    869. Doxorubicin-mediated apoptosis in glioma cells requir es NFAT3. (PubMed id 19784808)1, 9 Gopinath S....Rao J.S. (2009)
    870. Genetic variants in immunoregulatory genes and risk f or childhood lymphomas. (PubMed id 19508433)1, 9 Andrie E....Petridou E.T. (2009)
    871. Circulating TNFalpha levels in older men and women do not show independent prospective relations with MI or stroke. (PubMed id 19135670)1, 9 Jefferis B.J....Lowe G.D. (2009)
    872. Modulation of T lymphocyte replicative senescence via TNF-{alpha} inhibition: role of caspase-3. (PubMed id 19299722)1, 9 Parish S.T....Effros R.B. (2009)
    873. Identification of NR4A2 as a transcriptional activato r of IL-8 expression in human inflammatory arthritis. (PubMed id 19732956)1, 9 Aherne C.M....Murphy E.P. (2009)
    874. Psoriasis patients generate increased serum levels of autoantibodies to tumor necrosis factor-alpha and interferon-alpha. (PubMed id 19800767)1, 9 Bergman R....Karin N. (2009)
    875. The relation of adiponectin and tumor necrosis factor alpha levels between endothelial nitric oxide synthase, angiotensin-converting enzyme, transforming growth factor beta, and tumor necrosis factor alpha gene polymorphism in adrenal incidentalomas. (PubMed id 19498318)1, 9 Harman E....Yilmaz C. (2009)
    876. Cytokine gene polymorphisms in heavy drinkers with and without decompensated liver disease: a case-control study. (PubMed id 19086955)1, 9 Gleeson D....Duff G.W. (2008)
    877. Myelodysplasia and anemia of chronic disease in human tumor necrosis factor-alpha transgenic mice. (PubMed id 18205195)1, 9 Capocasale R.J....Bugelski P.J. (2008)
    878. Depressive symptoms in patients with chronic hepatitis C are correlated with elevated plasma levels of interleukin-1beta and tumor necrosis factor-alpha. (PubMed id 18063307)1, 9 Loftis J.M....Hauser P. (2008)
    879. Association of cystic fibrosis transmembrane conductance regulator (CFTR) mutation/variant/haplotype and tumor necrosis factor (TNF) promoter polymorphism in hyperlipidemic pancreatitis. (PubMed id 17981921)1, 9 Chang Y.T....Wong J.M. (2008)
    880. Two modes of ERK activation by TNF in keratinocytes: different cellular outcomes and bi-directional modulation by vitamin D. (PubMed id 18080320)1, 9 Ziv E....Koren R. (2008)
    881. The -308 TNFalpha gene polymorphism in severe acute alcoholic hepatitis: identification of a new susceptibility marker. (PubMed id 18336639)1, 9 Nguyen-Khac E....Naassila M. (2008)
    882. Relationship between periodontal findings and the TNF-alpha Gene 1031T/C polymorphism in Turkish patients with Behcet's diseasedagger. (PubMed id 18355201)1, 9 Akman A....Yegin O. (2008)
    883. Genetic markers of tumour necrosis factor alpha in aggressive and chronic periodontitis. (PubMed id 18363738)1, 9 Schulz S....Reichert S. (2008)
    884. Genetic variation in tumor necrosis factor and the nuclear factor-kappaB canonical pathway and risk of non-Hodgkin's lymphoma. (PubMed id 18990758)1, 9 Cerhan J.R....Slager S.L. (2008)
    885. The role of IL-12 and TNF-alpha in AIDP and AMAN. (PubMed id 18717726)1, 9 Deng H....Zhu J. (2008)
    886. Tumor necrosis factor-alpha antagonism improves endothelial dysfunction in patients with Crohn's disease. (PubMed id 17507924)1, 9 Schinzari F....Cardillo C. (2008)
    887. Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen. (PubMed id 19104039)1, 9 Lam L.T....Staudt L.M. (2008)
    888. BMP-7 protects mesangial cells from injury by polymeric IgA. (PubMed id 18496506)1, 9 Chan W.L....Lai K.N. (2008)
    889. Genetic factors of susceptibility and of severity in primary biliary cirrhosis. (PubMed id 18930330)1, 9 Poupon R....Barbu V. (2008)
    890. Cytokines induce an early steroid resistance in airway smooth muscle cells: novel role of interferon regulatory factor-1. (PubMed id 17947510)1, 9 Tliba O....Amrani Y. (2008)
    891. Impact of genetic polymorphisms of leptin and TNF-alpha on rosiglitazone response in Chinese patients with type 2 diabetes. (PubMed id 18438653)1, 9 Liu H.L....Liu Z.Q. (2008)
    892. Tumour necrosis factor gene polymorphisms are associated with COPD. (PubMed id 18256059)1, 9 Gingo M.R....Bowler R.P. (2008)
    893. Lack of association between the TNF-alpha -308 (G/A) genetic polymorphism and periodontal disease in Brazilians. (PubMed id 19148387)1, 9 Menezes N.G. and Colombo A.P. (2008)
    894. New approach reveals CD28 and IFNG gene interaction in the susceptibility to cervical cancer. (PubMed id 18337305)1, 9 Guzman V.B....Morgun A. (2008)
    895. Polymorphisms in cytokine genes and their association with acute rejection and recurrence of hepatitis B in Chinese liver transplant recipients. (PubMed id 18375254)1, 9 Xie H.Y....Zheng S.S. (2008)
    896. Constitutive activation of phosphatidylinositol 3-kinase signaling pathway down-regulates TLR4-mediated tumor necrosis factor-alpha release in alveolar macrophages from asymptomatic HIV-positive persons in vitro. (PubMed id 18826950)1, 9 Tachado S.D....Koziel H. (2008)
    897. Evaluation of functional single nucleotide polymorphisms of different genes coding for the immunoregulatory molecules in patients with monoclonal large granular lymphocyte lymphocytosis. (PubMed id 18361934)1, 9 Garrido P....Ruiz-Cabello F. (2008)
    898. Association of TNF-alpha and TNFR1 promoters and 3' UTR region of TNFR2 gene polymorphisms with genetic susceptibility to tobacco-related oral carcinoma in Asian Indians. (PubMed id 18206417)1, 9 Gupta R....Das S.N. (2008)
    899. Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures. (PubMed id 19017992)1, 9 Sacre S.M....Foxwell B.M. (2008)
    900. Tumour necrosis factor alpha upregulates platelet CD40L in patients with heart failure. (PubMed id 18281372)1, 9 Pignatelli P....Violi F. (2008)
    901. JNK modulates the effect of caspases and NF-kappaB in the TNF-alpha-induced down-regulation of Na+/K+ATPase in HepG2 cells. (PubMed id 18348163)1, 9 Kassardjian A. and Kreydiyyeh S.I. (2008)
    902. TNF-alpha is a positive regulatory factor for human Vgamma2 Vdelta2 T cells. (PubMed id 18981134)1, 9 Li H....Pauza C.D. (2008)
    903. Polymorphisms of tumor necrosis factor alpha gene and coronary heart disease in a Chinese Han population: Interaction with cigarette smoking. (PubMed id 18814905)1, 9 Hou L....Gu D. (2008)
    904. Distinct role of c-Jun N-terminal kinase isoforms in human neutrophil apoptosis regulated by tumor necrosis factor-alpha and granulocyte-macrophage colony-stimulating factor. (PubMed id 18439101)1, 9 Kato T....Kitagawa S. (2008)
    905. Differential flow cytometric detection of intracellular cytokines in peripheral and peritoneal mononuclear cells of women with endometriosis. (PubMed id 17207568)1, 9 Gmyrek G.B....Chel/monska-Soyta A. (2008)
    906. Serum TNF-alpha levels in relation to alcohol consumption and common TNF gene polymorphisms. (PubMed id 18579335)1, 9 Gonzalez-Quintela A....Gude F. (2008)
    907. Haplotypes of tumor necrosis factor gene and tracheal aspirate fluid levels of tumor necrosis factor-alpha in preterm infants. (PubMed id 18645461)1, 9 Kazzi S.N....Buhimschi I.A. (2008)
    908. TNF alpha-induced down-regulation of estrogen receptor alpha in MCF-7 breast cancer cells. (PubMed id 18483465)1, 9 Lee S.H. and Nam H.S. (2008)
    909. Reactive oxygen species in tumor necrosis factor-alpha-activated primary human keratinocytes: implications for psoriasis and inflammatory skin disease. (PubMed id 18463678)1, 9 Young C.N....Terlecky S.R. (2008)
    910. Human leucocyte antigen and TNFalpha polymorphism association in microscopic colitis. (PubMed id 18334870)1, 9 Koskela R.M....Karttunen R.A. (2008)
    911. Antithrombin inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by monocytes in vitro through inhibition of Egr-1 expression. (PubMed id 18088351)1, 9 Komura H....Okajima K. (2008)
    912. TNF-alpha-induced up-regulation of intercellular adhesion molecule-1 is regulated by a Rac-ROS-dependent cascade in human airway epithelial cells. (PubMed id 18446055)1, 9 Kim H....Lee S.S. (2008)
    913. Genetic variations in inflammatory mediators influence lung disease progression in cystic fibrosis. (PubMed id 19009622)1, 9 Corvol H....Clement A. (2008)
    914. Asymmetric dimethylarginine induces TNF-alpha production via ROS/NF-kappaB dependent pathway in human monocytic cells and the inhibitory effect of reinioside C. (PubMed id 18295546)1, 9 Zhang G.G....Li Y.J. (2008)
    915. Epistatic interactions are critical to gene-association studies: PAI-1 and risk for mortality after burn injury. (PubMed id 18182917)1, 9 Barber R.C....Horton J.W. (2008)
    916. Regulation of tenascin-C expression by tumor necrosis factor-alpha in cultured human osteoarthritis chondrocytes. (PubMed id 18061975)1, 9 Nakoshi Y....Uchida A. (2008)
    917. Raf-1 kinase mediates adenylyl cyclase sensitization by TNF-alpha in human airway smooth muscle cells. (PubMed id 17277048)1, 9 Osawa Y....Emala C.W. (2007)
    918. Polymorphisms in the CD14 and IL-6 genes associated with periodontal disease. (PubMed id 17448042)1, 9 Tervonen T....Karttunen R. (2007)
    919. Cytokine gene polymorphisms in Colombian patients with systemic lupus erythematosus. (PubMed id 17711410)1, 9 Guarnizo-Zuccardi P....Vasquez G. (2007)
    920. Linkage and association analysis of candidate genes for TB and TNFalpha cytokine expression: evidence for association with IFNGR1, IL-10, and TNF receptor 1 genes. (PubMed id 17431682)1, 9 Stein C.M....Iyengar S.K. (2007)
    921. IL-10 and IL-6 gene polymorphisms as potential host susceptibility factors in Brucellosis. (PubMed id 17544674)1, 9 Budak F....Oral H.B. (2007)
    922. Analysis of polymorphisms of tumor necrosis factor-alpha and polymorphic xenobiotic metabolizing enzymes in inflammatory bowel disease: study from northern India. (PubMed id 17565649)1, 9 Mittal R.D....Ghoshal U.C. (2007)
    923. Association between inflammatory gene polymorphisms and coronary artery disease in an Indian population. (PubMed id 18157711)1, 9 Banerjee I....Ganesh S. (2007)
    924. Frequency distribution of cytokine gene polymorphisms in the healthy North Indian population. (PubMed id 17257312)1, 9 Kaur G....Mehra N.K. (2007)
    925. The -308 tumour necrosis factor-alpha gene polymorphism predicts therapeutic response to TNFalpha-blockers in rheumatoid arthritis and spondyloarthritis patients. (PubMed id 16720636)1, 9 Seitz M....Villiger P.M. (2007)
    926. MAP kinase-dependent, NF-kappaB-independent regulation of inhibitor of apoptosis protein genes by TNF-alpha. (PubMed id 17133355)1, 9 Furusu A....Kitamura M. (2007)
    927. Development of a novel microarray methodology for the study of SNPs in the promoter region of the TNF-alpha gene: their association with obstructive pulmonary disease in Greek patients. (PubMed id 17509552)1, 9 Papatheodorou A....Tzetis M. (2007)
    928. Cytokine genotype and phenotype effects on lung function decline in firefighters. (PubMed id 17351514)1, 9 Josyula A.B....Burgess J.L. (2007)
    929. Phenotype selection for detecting variable genes: a survey of cardiovascular quantitative traits and TNF locus polymorphism. (PubMed id 17356550)1, 9 Hong M.G....Prince J.A. (2007)
    930. Polymorphisms of tumor necrosis factor-alpha but not MDR1 influence response to medical therapy in pediatric-onset inflammatory bowel disease. (PubMed id 17255827)1, 9 Cucchiara S....Annese V. (2007)
    931. Perfusion with lipopolysaccharide differently affects the secretion of tumor necrosis factor-alpha and interleukin-6 by term and preterm human placenta. (PubMed id 17194482)1, 9 Holcberg G....Huleihel M. (2007)
    932. Genetic susceptibility to SLE is associated with TNF-alpha gene polymorphism -863, but not -308 and -238, in Thai population. (PubMed id 18001298)1, 9 Hirankarn N....Wongpiyabovorn J. (2007)
    933. IL2 and TNFA gene polymorphisms and the risk of graft-versus-host disease after allogeneic haematopoietic stem cell transplantation. (PubMed id 18021367)1, 9 Viel D.O....Visentainer J.E. (2007)
    934. Tumor necrosis factor-alpha gene polymorphism correlates with cardiovascular disease in patients with end-stage renal disease. (PubMed id 17705580)1, 9 Buraczynska M....Ksiazek A. (2007)
    935. Immune mechanisms in non-Hodgkin lymphoma: joint effects of the TNF G308A and IL10 T3575A polymorphisms with non-Hodgkin lymphoma risk factors. (PubMed id 17510437)1, 9 Wang S.S....Hartge P. (2007)
    936. Significant association between TNF-alpha (TNF) promoter allele (-1031C, -863C, and -857C) and cerebral malaria in Thailand. (PubMed id 17493155)1, 9 Hananantachai H....Tokunaga K. (2007)
    937. The priming effect of C5a on monocytes is predominantly mediated by the p38 MAPK pathway. (PubMed id 17505301)1, 9 Schaeffer V....Maier R. (2007)
    938. [Association of cytokines genes (ILL, IL1RN, TNF, LTA, IL6, IL8, IL0) polymorphic markers with chronic obstructive pulmonary disease] (PubMed id 17380888)1, 9 Danilko K.V....Victorova T.V. (2007)
    939. Analysis of IL-1A(-889) and TNFA(-308) gene polymorphism in Brazilian patients with generalized aggressive periodontitis. (PubMed id 17823082)1, 9 Maria de Freitas N....Lotufo R.F. (2007)
    940. A possible role for TSLP in inflammatory arthritis. (PubMed id 17416344)1, 9 Koyama K....Nakao A. (2007)
    941. PPARgamma gene C161T substitution is associated with reduced risk of coronary artery disease and decreased proinflammatory cytokine expression. (PubMed id 17892998)1, 9 Liu Y....Ma A. (2007)
    942. RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation. (PubMed id 17449468)1, 9 Tian Y....Shu H.B. (2007)
    943. Induction of interleukin-8 (CXCL-8) by tumor necrosis factor-alpha and leukemia inhibitory factor in pancreatic carcinoma cells: Impact of CXCL-8 as an autocrine growth factor. (PubMed id 17671691)1, 9 Kamohara H....Baba H. (2007)
    944. Comparison of the human and canine cytokines IL-1(alpha/beta) and TNF-alpha to orthologous other mammalians. (PubMed id 17573384)1, 9 Soller J.T....Nolte I. (2007)
    945. Prevotella intermedia lipopolysaccharide stimulates release of tumor necrosis factor-alpha through mitogen-activated protein kinase signaling pathways in monocyte-derived macrophages. (PubMed id 17727652)1, 9 Kim S.J....Choi I.S. (2007)
    946. TNF polymorphisms in psoriasis: association of psoriatic arthritis with the promoter polymorphism TNF*-857 independent of the PSORS1 risk allele. (PubMed id 17530646)1, 9 Reich K....Burkhardt H. (2007)
    947. Tumour necrosis factor and lymphotoxin A polymorphisms and lung function in smokers. (PubMed id 16971410)1, 9 Tanaka G....He J.Q. (2007)
    948. Synergism in the repression of COX-2- and TNFalpha-induction in platelet activating factor-stressed human neural cells. (PubMed id 17881124)1, 9 Boetkjaer A....Lukiw W.J. (2007)
    949. Association of polymorphisms within the promoter region of the tumor necrosis factor-alpha with clinical outcomes of rheumatic fever. (PubMed id 17079017)1, 9 Ramasawmy R....Guilherme L. (2007)
    950. Berberine suppresses inflammatory agents-induced interleukin-1beta and tumor necrosis factor-alpha productions via the inhibition of IkappaB degradation in human lung cells. (PubMed id 17681786)1, 9 Lee C.H....Ho T.Y. (2007)
    951. GSTM1 and TNF-alpha gene polymorphisms and relations between blood lead and inflammatory markers in a non-occupational population. (PubMed id 17298885)1, 9 Kim J.H....Hong Y.C. (2007)
    952. Association of TNF-alpha -308 G/A and IL-4 -589 C/T gene promoter polymorphisms with asthma susceptibility in the south of Iran. (PubMed id 18088017)1, 9 Kamali-Sarvestani E....Nekoee A. (2007)
    953. 1,25(OH)(2)D(3) blocks TNF-induced monocytic tissue factor expression by inhibition of transcription factors AP-1 and NF-kappaB. (PubMed id 17401435)1, 9 Chung J....Hirosawa S. (2007)
    954. Post-induction, stimulus-specific regulation of tumor necrosis factor mRNA expression. (PubMed id 17303559)1, 9 Tsytsykova A.V....Goldfeld A.E. (2007)
    955. TNF-alpha induces transient resistance to Fas-induced apoptosis in eosinophilic acute myeloid leukemia cells. (PubMed id 17349210)1, 9 Qin Y....Hamann K.J. (2007)
    956. Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation. (PubMed id 17079667)1, 9 Mastronardi F.G....Moscarello M.A. (2006)
    957. Cytokine gene polymorphisms can alter the effect of Bacillus Calmette-Guerin (BCG) immunotherapy. (PubMed id 16938461)1, 9 Basturk B....Oktay B. (2006)
    958. Association of HLA-A, -B, -C genes and TNF microsatellite polymorphism with psoriasis vulgaris: a study of genetic risk in Brazilian patients. (PubMed id 17101473)1, 9 Biral A.C....Kraemer M.H. (2006)
    959. Glucose ingestion induces an increase in intranuclear nuclear factor kappaB, a fall in cellular inhibitor kappaB, and an increase in tumor necrosis factor alpha messenger RNA by mononuclear cells in healthy human subjects. (PubMed id 16919536)1, 9 Aljada A....Dandona P. (2006)
    960. Association between chronic hepatitis B virus infection and interleukin-10, tumor necrosis factor-alpha gene promoter polymorphisms. (PubMed id 16824070)1, 9 Cheong J.Y....Kim J.H. (2006)
    961. Alleles 308A and 238A in the tumor necrosis factor alpha gene promoter do not increase the risk of severe malaria in children with Plasmodium falciparum infection in Mali. (PubMed id 16982833)1, 9 Cabantous S....Marquet S. (2006)
    962. A membrane form of TNF-alpha presented by exosomes delays T cell activation-induced cell death. (PubMed id 16751383)1, 9 Zhang H.G....Kimberly R.P. (2006)
    963. Activation of toll-like receptor-9 induces matrix metalloproteinase-9 expression through Akt and tumor necrosis factor-alpha signaling. (PubMed id 16870179)7, 9 Lim E.J....Baek S.H. (2006)
    964. The effect of ciprofloxacin on CD14 and toll-like receptor-4 expression on human monocytes. (PubMed id 16552356)1, 9 Katsuno G....Tanaka N. (2006)
    965. Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. (PubMed id 16603398)1, 9 Ea C.K....Chen Z.J. (2006)
    966. A new transcription factor that regulates TNF-alpha gene expression, LITAF, is increased in intestinal tissues from patients with CD and UC. (PubMed id 16804395)1, 9 Stucchi A....Becker J. (2006)
    967. Tumour necrosis factor microsatellite haplotypes are associated with chronic pancreatitis. (PubMed id 16407614)1, 9 O'Reilly D.A....Kingsnorth A.N. (2006)
    968. Role of single nucleotide polymorphisms of cytokine genes in spontaneous preterm delivery. (PubMed id 17145371)1, 9 Speer E.M....Skoner D.P. (2006)
    969. Analysis of tumor necrosis factor-alpha, transforming growth factor-beta, interleukin-10, IL-6, and interferon-gamma gene polymorphisms in patients with chronic periodontitis. (PubMed id 17209781)1, 9 Babel N....Reinke P. (2006)
    970. Three allele combinations associated with multiple sclerosis. (PubMed id 16872485)1, 9 Favorova O.O....Ochs M.F. (2006)
    971. Pneumocystis jiroveci pneumonia in a patient with rheumatoid arthritis as a complication of treatment with infliximab, anti-tumor necrosis factor alpha neutralizing antibody. (PubMed id 16622728)7, 9 Mori S....Sugimoto M. (2006)
    972. Meta-analysis of TNF-alpha promoter -308 A/G polymorphism and SLE susceptibility. (PubMed id 16418737)1, 9 Lee Y.H....Nath S.K. (2006)
    973. Transactivator of transcription from HIV type 1 subtype E selectively inhibits TNF gene expression via interference with chromatin remodeling of the TNF locus. (PubMed id 16547255)1, 9 Ranjbar S....Goldfeld A.E. (2006)
    974. TNF-857 polymorphism in Israeli Jewish patients with inflammatory bowel disease. (PubMed id 16611251)1, 9 Fidder H.H....Crusius J.B. (2006)
    975. Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2. (PubMed id 16424170)1, 9 Johansen C....Iversen L. (2006)
    976. [Association between tumor necrosis factor-alpha gene polymorphism and insulin resistance in nonalcoholic fatty liver disease] (PubMed id 16938178)1, 9 Huang J....Zhou Y.J. (2006)
    977. Association between vitamin D receptor, CCR5, TNF-alpha and TNF-beta gene polymorphisms and HBV infection and severity of liver disease. (PubMed id 16545485)1, 9 Suneetha P.V....Hissar S. (2006)
    978. Increased expression of membrane TNF-alpha on activated peripheral CD8+ T cells in systemic lupus erythematosus. (PubMed id 16596274)1, 9 Horiuchi T....Okamura S. (2006)
    979. Cytokine tumor necrosis factor-alpha A promoter gene polymorphism at position -308 G-->A and pediatric inflammatory bowel disease: implications in ulcerative colitis and Crohn's disease. (PubMed id 16707968)1, 9 Sykora J....Stozicky F. (2006)
    980. Protein kinase Czeta is up-regulated in osteoarthritic cartilage and is required for activation of NF-kappaB by tumor necrosis factor and interleukin-1 in articular chondrocytes. (PubMed id 16798739)1, 9 LaVallie E.R....Arai M. (2006)
    981. Involvement of -308 TNF-alpha and 1267 Hsp70-2 polymorphisms and zinc status in the susceptibility of coronary artery disease (CAD) in old patients. (PubMed id 16953332)1, 9 Giacconi R....Mocchegiani E. (2006)
    982. Tumor necrosis factor- alpha promoter polymorphism at position -308 predicts response to combination therapy in hepatitis C virus infection. (PubMed id 16323137)1, 9 Dai C.Y....Yu M.L. (2006)
    983. TNFalpha genotype influences development of IgA-ASCA antibodies in Crohn's disease patients with CARD15 wild type. (PubMed id 16952484)1, 9 Castro-Santos P....Suarez A. (2006)
    984. Interleukin-10 or tumor necrosis factor-alpha polymorphisms and the natural course of hepatitis C virus infection in a hyperendemic area of Japan. (PubMed id 16698276)1, 9 Kusumoto K....Tsubouchi H. (2006)
    985. Mitogen-activated protein kinase kinase 1/extracellular signal-regulated kinase (MEK-1/ERK) inhibitors sensitize reduced glucocorticoid response mediated by TNFalpha in human epidermal keratinocytes (HaCaT). (PubMed id 17054908)1, 9 Onda K....Oka K. (2006)
    986. Association of TNF-alpha serum levels and TNFA promoter polymorphisms with risk of myocardial infarction. (PubMed id 16243340)1, 9 Bennet A.M....de Faire U. (2006)
    987. Protein tyrosine kinase and p38 MAP kinase pathways are involved in stimulation of matrix metalloproteinase-9 by TNF-alpha in human monocytes. (PubMed id 16720051)1, 9 Nguyen J....Bauvois B. (2006)
    988. Role of TNFalpha in pulmonary pathophysiology. (PubMed id 17034639)1, 9 Mukhopadhyay S....Mukherjee T.K. (2006)
    989. Polymorphisms within the tumor necrosis factor-alpha promoter region in patients with HLA-B27-associated uveitis: association with susceptibility and clinical manifestations. (PubMed id 16581430)1, 9 El-Shabrawi Y....Hermann J. (2006)
    990. Genetic susceptibility to ulcerative colitis in the Chinese Han ethnic population: association with TNF polymorphisms. (PubMed id 16863613)1, 9 Cao Q....Si J.M. (2006)
    991. Lack of association between TNFalpha gene polymorphism at position -308 and risk of acute rheumatic fever in Turkish patients. (PubMed id 16467041)1, 9 Berdeli A....Aydin H.H. (2006)
    992. Lack of association with TNF-alpha-308 promoter polymorphism in patients with vitiligo. (PubMed id 16691430)1, 9 Yazici A.C....Tursen U. (2006)
    993. TNF alpha inhibitors in the treatment of psoriasis and psoriatic arthritis. (PubMed id 15691217)7, 9 Tobin A.M. and Kirby B. (2005)
    994. Autoimmunity and tuberculosis. Opposite association with TNF polymorphism. (PubMed id 15693080)1, 9 Correa P.A....Anaya J.M. (2005)
    995. Proinflammatory factors present in sera from patients with acute dengue infection induce activation and apoptosis of human microvascular endothelial cells: possible role of TNF-alpha in endothelial cell damage in dengue. (PubMed id 15935956)1, 9 Cardier J.E....Rothman A.L. (2005)
    996. Association of tumour necrosis factor alpha variants with the CF pulmonary phenotype. (PubMed id 15790988)1, 9 Yarden J....Cuppens H. (2005)
    997. Lack of association between TNF-308 polymorphism and the clinical and immunological characteristics of systemic lupus erythematosus and primary Sjogren's syndrome. (PubMed id 15971421)1, 9 Tobon G.J....Anaya J.M. (2005)
    998. Tumor necrosis factor-alpha promoter polymorphism in Mexican patients with Chagas' disease. (PubMed id 15790514)1, 9 Rodriguez-Perez J.M....Vargas-Alarcon G. (2005)
    999. A soybean Kunitz trypsin inhibitor reduces tumor necrosis factor-alpha production in ultraviolet-exposed primary human keratinocytes. (PubMed id 16176285)1, 9 Kobayashi H....Terao T. (2005)
    1000. Effect of cytokine gene polymorphism on histological activity index, viral load and response to treatment in patients with chronic hepatitis C genotype 3. (PubMed id 16425360)1, 9 Abbas Z....Jafri W. (2005)
    1001. Tumour necrosis factor gene polymorphisms and childhood wheezing. (PubMed id 16204594)1, 9 Bilolikar H....Balfour-Lynn I.M. (2005)
    1002. Tumor necrosis factor-alpha-induced iron sequestration and oxidative stress in human endothelial cells. (PubMed id 16224057)1, 9 Nanami M....Nakanishi T. (2005)
    1003. Sulfasalazine and BAY 11-7082 interfere with the nuclear factor-kappa B and I kappa B kinase pathway to regulate the release of proinflammatory cytokines from human adipose tissue and skeletal muscle in vitro. (PubMed id 15564333)1, 9 Lappas M....Rice G.E. (2005)
    1004. Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression. (PubMed id 15681825)1, 9 Wang F....Turner J.R. (2005)
    1005. Synergistic induction of tissue factor by coagulation factor Xa and TNF: evidence for involvement of negative regulatory signaling cascades. (PubMed id 16105945)1, 9 Hezi-Yamit A....Sinha U. (2005)
    1006. Early growth response factor-1 mediates prostaglandin E2-dependent transcriptional suppression of cytokine-induced tumor necrosis factor-alpha gene expression in human macrophages and rheumatoid arthritis-affected synovial fibroblasts. (PubMed id 15640148)1, 9 Faour W.H....Di Battista J.A. (2005)
    1007. Accumulation of p53 in response to adenovirus early region 1A sensitizes human cells to tumor necrosis factor alpha-induced apoptosis. (PubMed id 16051302)1, 9 Zhang X....Grand R.J. (2005)
    1008. The tumour necrosis factor (TNF)-alpha system is activated in accordance with pulse pressure in normotensive subjects with type 1 diabetes mellitus. (PubMed id 16260427)1, 9 Gonzalez-Clemente J.M....Vendrell J. (2005)
    1009. Human resistin stimulates the pro-inflammatory cytokines TNF-alpha and IL-12 in macrophages by NF-kappaB-dependent pathway. (PubMed id 16039994)1, 9 Silswal N....Ehtesham N.Z. (2005)
    1010. The Met-196 -> Arg variation of human tumor necrosis factor receptor 2 (TNFR2) affects TNF-alpha-induced apoptosis by impaired NF-kappaB signaling and target gene expression. (PubMed id 15572357)1, 9 Till A....Schreiber S. (2005)
    1011. [Study on the association between gestational diabetes mellitus and tumor necrosis factor-alpha gene polymorphism] (PubMed id 16277898)1, 9 Chang Y....Luo Y. (2005)
    1012. Polymorphisms of TNFalpha, IL1beta, and IL1RN genes in chronic obstructive pulmonary disease. (PubMed id 15766560)1, 9 Hegab A.E....Sekizawa K. (2005)
    1013. Thiazolidinediones inhibit TNFalpha induction of PAI-1 independent of PPARgamma activation. (PubMed id 15990085)1, 9 Liu H.B....Dear A.E. (2005)
    1014. Tumor necrosis factor alpha activates the human plasminogen activator inhibitor-1 gene through a distal nuclear factor kappaB site. (PubMed id 14963043)1, 9 Hou B....Vaughan D.E. (2004)
    1015. Lack of association between the TNF alpha G -308 A promoter polymorphism and periodontal disease. (PubMed id 15142214)1, 9 Folwaczny M....Folwaczny C. (2004)
    1016. Hypothermia prolongs activation of NF-kappaB and augments generation of inflammatory cytokines. (PubMed id 15070815)1, 9 Fairchild K.D....Hasday J.D. (2004)
    1017. Association of TNF-beta polymorphism with disease severity among patients infected with hepatitis C virus. (PubMed id 14635012)1, 9 Goyal A....Sarin S.K. (2004)
    1018. The differential effects of IL-1 and TNF-alpha on proinflammatory cytokine and matrix metalloproteinase expression in human chondrosarcoma cells. (PubMed id 15316669)1, 9 Shi J....Dullea R.G. (2004)
    1019. Polymorphism of promotor region of the tumor necrosis factor-alpha gene in patients with viral hepatitis C. (PubMed id 15232637)1, 9 Smol'nikova M.V....Konenkov V.I. (2004)
    1020. Characterization of the survival effect of tumour necrosis factor-alpha in human neutrophils. (PubMed id 15157159)1, 9 Walmsley S.R....Chilvers E.R. (2004)
    1021. An analysis of tumor necrosis factor alpha gene polymorphisms and haplotypes with natural clearance of hepatitis C virus infection. (PubMed id 15071492)1, 9 Thio C.L....Thomas D.L. (2004)
    1022. Role of the HLA-DP Glu 69 and the TNF-alpha TNF-alpha 2 gene markers in susceptibility to beryllium hypersensitivity. (PubMed id 15345185)1, 9 Rogliani P....Saltini C. (2004)
    1023. HIV-1 Tat increases the adhesion of monocytes and T-cells to the endothelium in vitro and in vivo: implications for AIDS-associated vasculopathy. (PubMed id 15246652)1, 9 Matzen K....Sturzl M. (2004)
    1024. Influence of TNF gene polymorphism in patients with acute and fulminant hepatitis. (PubMed id 15565405)1, 9 Tsuchiya N....Shiratori K. (2004)
    1025. Association of -238G/A polymorphism of tumor necrosis factor-alpha gene promoter region with outcomes of hepatitis B virus infection in Chinese Han population. (PubMed id 15188512)1, 9 Lu L.P....Li H. (2004)
    1026. Soluble Fas and soluble FasL in multiple organ dysfunction syndrome complicating diffuse peritonitis. (PubMed id 17564320)1, 9 Kitamura M....Wakabayashi G. (2004)
    1027. TNF-alpha-308A allele, a possible severity risk factor of hemorrhagic manifestation in dengue fever patients. (PubMed id 15361124)1, 9 Fernandez-Mestre M.T....Layrisse Z. (2004)
    1028. Effect of tumor necrosis factor-alpha and interferon-gamma on intestinal P-glycoprotein expression, activity, and localization in Caco-2 cells. (PubMed id 15124210)1, 9 Belliard A.M....Leroy C. (2004)
    1029. An investigation into the association among preterm birth, cytokine gene polymorphisms and periodontal disease. (PubMed id 14723749)1, 9 Moore S....Simpson N.A. (2004)
    1030. SLC11A1 promoter gene polymorphisms and fibrosis progression in chronic hepatitis C. (PubMed id 14960532)1, 9 Romero-Gomez M....Gonzalez-Escribano M.F. (2004)
    1031. Tumour necrosis factor alpha, lipid peroxidation and NO* are increased and associated with decreased free-radical scavenging enzymes in patients with Weill-Marchesani syndrome. (PubMed id 15223607)1, 9 Evereklioglu C....Karabulut A.B. (2004)
    1032. Protein phosphatase 4 interacts with and down-regulates insulin receptor substrate 4 following tumor necrosis factor-alpha stimulation. (PubMed id 15331607)1, 9 Mihindukulasuriya K.A.... Tan T.-H. (2004)
    1033. Analysis of candidate genes in Polish families with obesity. (PubMed id 15202783)1, 9 Malczewska-Malec M....Dembinska-Kiec A. (2004)
    1034. Adverse outcomes after preterm labor are associated with tumor necrosis factor-alpha polymorphism -863, but not -308, in mother-infant pairs. (PubMed id 15507966)1, 9 Amory J.H....Hitti J. (2004)
    1035. Ethnic differences in polymorphisms of tumor necrosis factor-alpha, interleukin-10, and transforming growth factor-beta1 genes in patients with chronic hepatitis C virus infection. (PubMed id 15100460)1, 9 Zein N.N....Vidigal P.G. (2004)
    1036. Tumor necrosis factor-alpha gene expression and release in cultured human dermal microvascular endothelial cells. (PubMed id 15009105)1, 9 Hoffmann G....Sepp N. (2004)
    1037. Tumor necrosis factor-alpha-308 promoter and p53 codon 72 gene polymorphisms in women with leiomyomas. (PubMed id 15474092)1, 9 Hsieh Y.Y....Tsai C.H. (2004)
    1038. Tumor necrosis factor alpha promoter polymorphisms at position -308 in Taiwanese chronic hepatitis C patients treated with interferon-alpha. (PubMed id 12834858)1, 9 Yu M.L....Chang W.Y. (2003)
    1039. Tumour necrosis factor-alpha polymorphism as one of the complex inherited factors in pemphigus. (PubMed id 14760938)1, 9 Torzecka J.D....Kowalski M.L. (2003)
    1040. Serum amyloid A1 and tumor necrosis factor-alpha alleles in Turkish familial Mediterranean fever patients with and without amyloidosis. (PubMed id 12762136)1, 9 Akar N....Cakar N. (2003)
    1041. Survival during treatment with tumour necrosis factor blocking agents in rheumatoid arthritis. (PubMed id 14532145)7, 9 Flendrie M....van Riel P.L. (2003)
    1042. [New immunological weapons for medicine in the 21st Century: biological therapy based on the use of the latest generation monoclonal antibodies] (PubMed id 15022409)7, 9 AguillA^n J.C....Cuchacovich M. (2003)
    1043. Release of TNF-alpha during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers. (PubMed id 14659806)1, 9 Gilles S....Becker B.F. (2003)
    1044. c-Src-dependent tyrosine phosphorylation of IKKbeta is involved in tumor necrosis factor-alpha-induced intercellular adhesion molecule-1 expression. (PubMed id 12645577)1, 9 Huang W.C....Chen C.C. (2003)
    1045. Unopposed matrix metalloproteinase-9 expression in human tuberculous granuloma and the role of TNF-alpha-dependent monocyte networks. (PubMed id 14607966)1, 9 Price N.M....Friedland J.S. (2003)
    1046. TNF-alpha and IFN-gamma are overexpressed in the bone marrow of Fanconi anemia patients and TNF-alpha suppresses erythropoiesis in vitro. (PubMed id 12750172)1, 9 Dufour C....Pistoia V. (2003)
    1047. ANP inhibits TNF-alpha-induced endothelial MCP-1 expression--involvement of p38 MAPK and MKP-1. (PubMed id 12960255)1, 9 Weber N.C....Kiemer A.K. (2003)
    1048. Association between levels of TNF-alpha and TNF-alpha promoter -308 A/A polymorphism in children with Kawasaki disease. (PubMed id 12783130)1, 9 Chien Y.H....Chiang B.L. (2003)
    1049. Tumor necrosis factor-alpha induces functionally active hyaluronan-adhesive CD44 by activating sialidase through p38 mitogen-activated protein kinase in lipopolysaccharide-stimulated human monocytic cells. (PubMed id 12867430)1, 9 Gee K....Kumar A. (2003)
    1050. Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression. (PubMed id 12707358)1, 9 Huang W.C....Chen C.C. (2003)
    1051. Association of IL-10 polymorphism with severity of illness in community acquired pneumonia. (PubMed id 12554901)1, 9 Gallagher P.M....O'Neill S.J. (2003)
    1052. Tumor necrosis factor-alpha levels and promoter polymorphism in patients with Kawasaki disease in Korea. (PubMed id 14703611)1, 9 Ahn S.Y....Kim D.S. (2003)
    1053. TNF-alpha -308A promoter polymorphism is associated with enhanced TNF-alpha production and inflammatory activity in Crohn's patients with fistulizing disease. (PubMed id 12809834)1, 9 Gonzalez S....Lopez-Larrea C. (2003)
    1054. Tumor necrosis factor-alpha promoter polymorphisms and the risk of rejection after liver transplantation: a case control analysis of 210 donor-recipient pairs. (PubMed id 12682890)1, 9 Jazrawi S.F....Rosen H.R. (2003)
    1055. Decreased frequency of the tumor necrosis factor alpha -308 allele in Serbian patients with multiple sclerosis. (PubMed id 12824709)1, 9 Drulovic J....Mostarica Stojkovic M. (2003)
    1056. Interferon-gamma differentially regulates monocyte matrix metalloproteinase-1 and -9 through tumor necrosis factor-alpha and caspase 8. (PubMed id 12960156)1, 9 Zhou M....Wahl L.M. (2003)
    1057. Tumor necrosis factor (TNF)alpha and its soluble receptor (sTNFR) p75 during acute human parvovirus B19 infection in children. (PubMed id 12880679)1, 9 Barash J....Hahn T. (2003)
    1058. [Role of TNF-alpha and cytokines in the physiopathology of rheumatoid arthritis. Therapeutic perspectives] (PubMed id 14979058)1, 9 Meyer O. (2003)
    1059. Involvement of G(i) proteins and Src tyrosine kinase in TNFalpha production induced by lipopolysaccharide, group B Streptococci and Staphylococcus aureus. (PubMed id 12842760)1, 9 Fan H....Cook J.A. (2003)
    1060. The possible role of tumor necrosis factor-alpha in diabetic polyneuropathy. (PubMed id 14630568)1, 9 Satoh J....Toyota T. (2003)
    1061. Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression. (PubMed id 12829646)1, 9 Kern P.A....Ranganathan G. (2003)
    1062. Surfactant protein A inhibits peptidoglycan-induced tumor necrosis factor-alpha secretion in U937 cells and alveolar macrophages by direct interaction with toll-like receptor 2. (PubMed id 11724772)1, 9 Murakami S....Kuroki Y. (2002)
    1063. Activated protein C inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by inhibiting activation of both nuclear factor-kappa B and activator protein-1 in human monocytes. (PubMed id 12195699)1, 9 Yuksel M....Okabe H. (2002)
    1064. TNF alpha and LT alpha gene polymorphisms as additional markers of celiac disease susceptibility in a DQ2-positive population. (PubMed id 12439617)1, 9 Garrote J.A....Blanco-Quiros A. (2002)
    1065. Genetic factors associated with development of cerebral malaria and fibrotic schistosomiasis. (PubMed id 12509099)4, 9 Hirayama K. (2002)
    1066. The mutagenically separated polymerase chain reaction is a rapid and reliable method for genotyping of the tumour necrosis factor-alpha promoter polymorphism (-308 G/A). (PubMed id 11983212)1, 9 Schluter B....Assmann G. (2002)
    1067. Tumor necrosis factor-alpha +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease. (PubMed id 12537602)1, 9 Kucukaycan M....Wouters E.F. (2002)
    1068. Major histocompatibility complex class I chain related (MIC) A gene, TNFa microsatellite alleles and TNFB alleles in juvenile idiopathic arthritis patients from Latvia. (PubMed id 11975986)1, 9 Nikitina Zake L....Sanjeevi C.B. (2002)
    1069. [Tumor necrosis factor alpha genetic polymorphism as a risk factor in disease] (PubMed id 12434654)4, 9 Aguillon J.C....Cuchacovich M. (2002)
    1070. Downregulation of angiotensin converting enzyme by TNF-alpha in differentiating human macrophages. (PubMed id 12160518)1, 9 Viinikainen A....Saijonmaa O. (2002)
    1071. Immunopharmacological potential of selective phosphodiesterase inhibition. I. Differential regulation of lipopolysaccharide-mediated proinflammatory cytokine (interleukin-6 and tumor necrosis factor-alpha) biosynthesis in alveolar epithelial cells. (PubMed id 11805217)7, 9 Haddad J.J....Lauterbach R. (2002)
    1072. Differential TNFalpha mRNA regulation detected in the epidermis of leprosy patients. (PubMed id 12420104)1, 9 Teles R.M....Sampaio E.P. (2002)
    1073. Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells. (PubMed id 12370346)1, 9 Messmer D....Pope M. (2002)
    1074. Cathepsin B mediates tumor necrosis factor-induced arachidonic acid release in tumor cells. (PubMed id 12185082)1, 9 Foghsgaard L....Jaattela M. (2002)
    1075. Modulation of TNF and GM-CSF release from dispersed human nasal polyp cells and human whole blood by inhibitors of different PDE isoenzymes and glucocorticoids. (PubMed id 11969359)7, 9 Marx D....Szelenyi I. (2002)
    1076. Insulin-like growth factor binding protein-3 mediates tumor necrosis factor-alpha-induced apoptosis: role of Bcl-2 phosphorylation. (PubMed id 11971816)1, 9 Rajah R....Cohen P. (2002)
    1077. Template-directed dye-terminator incorporation with fluorescence polarization detection for analysis of single nucleotide polymorphisms implicated in sepsis. (PubMed id 12411588)4, 9 Freeman B.D....Zehnbauer B.A. (2002)
    1078. 15 deoxy delta12,14 PGJ2 induces procoagulant activity in cultured human endothelial cells. (PubMed id 11916086)1, 9 Xie S....Scully M.F. (2002)
    1079. Estradiol represses human T-cell leukemia virus type 1 Tax activation of tumor necrosis factor-alpha gene transcription. (PubMed id 12237295)1, 9 Tzagarakis-Foster C....Leitman D.C. (2002)
    1080. CD40 ligation induces macrophage IL-10 and TNF-alpha production: differential use of the PI3K and p42/44 MAPK-pathways. (PubMed id 11792123)1, 9 Foey A.D....Brennan F.M. (2001)
    1081. Six microsatellite markers on the short arm of chromosome 6 in relation to HLA-DR3 and TNF-308A in systemic lupus erythematosus. (PubMed id 11704803)1, 9 van der Linden M.W....Huizinga T.W. (2001)
    1082. Differential mechanisms of plasminogen activator inhibitor-1 gene activation by transforming growth factor-beta and tumor necrosis factor-alpha in endothelial cells. (PubMed id 11776328)1, 9 Chen Y.Q....Tseng-Crank J. (2001)
    1083. Increased frequency of the tumor necrosis factor-alpha-308 A allele in adults with human immunodeficiency virus dementia. (PubMed id 11506397)1, 9 Quasney M.W....McArthur J. (2001)
    1084. Tumor necrosis factor alpha promoter polymorphisms influence the phenotypic expression of hereditary hemochromatosis. (PubMed id 11389006)1, 9 Fargion S....Fiorelli G. (2001)
    1085. Tumor necrosis factor-alpha -308 promoter gene polymorphism and increased tumor necrosis factor serum bioactivity in farmer's lung patients. (PubMed id 11179110)1, 9 Schaaf B.M....Zabel P. (2001)
    1086. Influence of tumor necrosis factor-alpha gene-308 polymorphism on the development of coronary vasculopathy after cardiac transplantation. (PubMed id 11744409)1, 9 Densem C.G....Brooks N.H. (2001)
    1087. A genetically determined high setting of TNF-alpha influences immunologic parameters of HLA-B8,DR3 positive subjects: implications for autoimmunity. (PubMed id 11423177)1, 9 Lio D....Caruso C. (2001)
    1088. Tumor necrosis factor and motoneuronal degeneration: an open problem. (PubMed id 11847479)1, 9 Ghezzi P. and Mennini T. (2001)
    1089. Polymorphisms in tumour necrosis factor alpha, interleukin-10 and transforming growth factor beta1 genes and end-stage liver disease. (PubMed id 11192323)1, 9 Bathgate A.J....Hutchinson I.V. (2000)
    1090. Contribution of TNF-alpha and IL-10 gene polymorphisms to graft-versus-host disease following allo-hematopoietic stem cell transplantation. (PubMed id 11223972)1, 9 Takahashi H....Koike T. (2000)
    1091. Plasma interleukin-10:Tumor necrosis factor (TNF)-alpha ratio is associated with TNF promoter variants and predicts malarial complications. (PubMed id 11023485)1, 9 May J....Kremsner P.G. (2000)
    1092. Increased TNFA*2, but not TNFB*1, allele frequency in Spanish atopic patients. (PubMed id 10923589)4, 9 Castro J....Blanco-Quiros A. (2000)
    1093. Independent contribution of HLA-DRB1 and TNF alpha promoter polymorphisms to the susceptibility to Crohn's disease. (PubMed id 11196680)4, 9 Kawasaki A....Tokunaga K. (2000)
    1094. Induction of interactions between CD44 and hyaluronic acid by a short exposure of human T cells to diverse pro-inflammatory mediators. (PubMed id 10929056)1, 9 Ariel A....Hershkoviz R. (2000)
    1095. Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages. (PubMed id 10843712)1, 9 Mayne M....Geiger J.D. (2000)
    1096. Human immunodeficiency virus type 1 Nef mediates sustained membrane expression of tumor necrosis factor and the related cytokine LIGHT on activated T cells. (PubMed id 11000208)1, 9 Lama J. and Ware C.F. (2000)
    1097. Antitumor necrosis factor therapy for inflammatory bowel disease: a review of agents, pharmacology, clinical results, and safety. (PubMed id 10338381)7, 9 Sandborn W.J. and Hanauer S.B. (1999)
    1098. Tumor necrosis factor alpha promoter polymorphism at position -238 is associated with chronic active hepatitis C infection. (PubMed id 9515764)4, 9 Hohler T....Rittner C. (1998)
    1099. TNF microsatellite a2, b3 and d2 alleles are associated with systemic lupus erythematosus. (PubMed id 9098928)4, 9 Hajeer A.H....Ollier W.E. (1997)
    1100. No primary association between the 308 polymorphism in the tumor necrosis factor alpha promoter region and insulin-dependent diabetes mellitus. (PubMed id 8882412)4, 9 Deng G.Y....She J.X. (1996)
    1101. A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-alpha concentrations and outcome of patients with severe sepsis. (PubMed id 8625623)4, 9 Stuber F....Schade U. (1996)
    1102. Association between polymorphisms in the TNF region and systemic lupus erythematosus in the Italian population. (PubMed id 8813745)4, 9 D'Alfonso S....Momigliano-Richiardi P. (1996)
    1103. HIV-1 Tat potentiates TNF-induced NF-kappa B activation and cytotoxicity by altering the cellular redox state. (PubMed id 7859743)1, 9 Westendorp M.O....Lehmann V. (1995)
    1104. Interaction of HIV-1 gp120 molecule fragments with human monocytes: different requirements for tumor necrosis factor-alpha and IL-6 production. (PubMed id 7704970)1, 9 Zembala M....Colizzi V. (1995)
    1105. -308 tumor necrosis factor (TNF) polymorphism is not associated with survival in severe sepsis and is unrelated to lipopolysaccharide inducibility of the human TNF promoter. (PubMed id 8832971)4, 9 Stuber F....Nedospasov S.A. (1995-1996)
    1106. Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans. (PubMed id 8383325)1, 9 Corbett J.A....McDaniel M.L. (1993)
    1107. Anti-b(2)GPI/b(2)GPI induced TF and TNF-a expression i n monocytes involving both TLR4/MyD88 and TLR4/TRIF signaling pathways. (PubMed id 22964479)1 Xie H....Yan J. (2013)
    1108. Modeling susceptibility to periodontitis. (PubMed id 23100272)1 Laine M.L....Loos B.G. (2013)
    1109. Pro-inflammatory cytokine gene polymorphisms and threa t for coronary heart disease in a North Indian Agrawal population. (PubMed id 23159874)1 Garg P.R....Ghosh P.K. (2013)
    1110. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    1111. Production of TNF-a and IL-1b by peripheral blood mono nuclear cells in carriers of different allele variants of the gene. (PubMed id 22808497)1 Silkov A.N....Sennikov S.V. (2012)
    1112. Lack of effects of the TNF-alpha and IL-10 gene polymo rphisms in Mexican patients with lepromatous leprosy. (PubMed id 22655468)1 Velarde Felix J.S....Murillo-Llanes J. (2012)
    1113. Dyslipidemia and changes in lipid profiles associated with rheumatoid arthritis and initiation of anti-tumor necrosis factor therapy. (PubMed id 22504829)1 Curtis J.R....Baser O. (2012)
    1114. Glucocorticoids antagonize tumor necrosis factor-a-sti mulated lipolysis and resistance to the antilipolytic effect of insulin in human adipocytes. (PubMed id 22949029)1 Lee M.J. and Fried S.K. (2012)
    1115. Angiotensin II induces tumor necrosis factor-a express ion and release from cultured human podocytes. (PubMed id 22223068)1 Rosa A.C....Fantozzi R. (2012)
    1116. Cytokine gene polymorphism and asthma susceptibility, progress and control level. (PubMed id 21637953)1 Daneshmandi S....Kalvanagh P.A. (2012)
    1117. Association of tumor necrosis factor alpha-308 promote r polymorphism with spondyloarthritides patients in Colombia. (PubMed id 21833533)1 Romero-Sanchez C....Valle-Onate R. (2012)
    1118. Association between TNF-a promoter G-308A and G-238A p olymorphisms and obesity. (PubMed id 21559831)1 Hedayati M....Azizi F. (2012)
    1119. Association of tumor necrosis factor a, interleukin 6, and interleukin 10 promoter polymorphism with proliferative diabetic retinopath y in type 2 diabetic subjects. (PubMed id 22105495)1 Paine S.K....Bhattacharya B. (2012)
    1120. Frequent and strong antibody-mediated natural killer c ell activation in response to HIV-1 Env in individuals with chronic HIV-1 infect ion. (PubMed id 22496218)1 Thobakgale C.F....Altfeld M. (2012)
    1121. Changes in plasma IL4, TNFa and CRP in response to reg ular passive smoking at home among healthy school children in Khartoum, Sudan. (PubMed id 23066418)1 Merghani T.H....Alawad A. (2012)
    1122. Association of tumor necrosis factor-a gene promoter p olymorphism at sites -308 and -238 with non-alcoholic fatty liver disease: a met a-analysis. (PubMed id 22097889)1 Wang J.K....Tao X.Y. (2012)
    1123. Cyclophilin B attenuates the expression of TNF-a in li popolysaccharide-stimulated macrophages through the induction of B cell lymphoma -3. (PubMed id 22798670)1 Marcant A....Allain F. (2012)
    1124. Sphingosine mediates TNFa-induced lysosomal membrane p ermeabilization and ensuing programmed cell death in hepatoma cells. (PubMed id 22454477)1 Ullio C....Autelli R. (2012)
    1125. HCMV-encoded UL128 enhances TNF-a and IL-6 expression and promotes PBMC proliferation through the MAPK/ERK pathway in vitro. (PubMed id 22486303)1 Zheng Q....Zhao N. (2012)
    1126. Tumor necrosis factor-a pathway plays a critical role in regulating interferon-g induced protein-10 production in initial allogeneic h uman monocyte-endothelial cell interactions. (PubMed id 22564606)1 Fang Y.S....Xu H. (2012)
    1127. TNF promoter -308 A/G and -238 A/G polymorphisms and j uvenile idiopathic arthritis: a meta-analysis. (PubMed id 22696185)1 Lee Y.H....Song G.G. (2012)
    1128. Tumour necrosis factor-a-857T allele reduces the risk of hepatitis B virus infection in an Asian population. (PubMed id 22239528)1 Shi K.Q....Zheng M.H. (2012)
    1129. Relationships between tumour necrosis factor-a, interl eukin-12B and interleukin-10 gene polymorphisms and hepatitis B in Chinese Han h aemodialysis patients. (PubMed id 22070668)1 Wang C....Zhao W. (2012)
    1130. The age-dependency of genetic and environmental influe nces on serum cytokine levels: a twin study. (PubMed id 22673037)1 Sas A.A....Snieder H. (2012)
    1131. Genetic variants of TNFa, IL10, IL1b, CTLA4 and TGFb1 modulate the indices of alcohol-induced liver injury in East Indian population. (PubMed id 22902304)1 Roy N....Chowdhury A. (2012)
    1132. Transglutaminase 2 expression is enhanced synergistica lly by interferon-g and tumour necrosis factor-a in human small intestine. (PubMed id 22385244)1 Bayardo M....Chirdo F. (2012)
    1133. The importance of genetic variants in TNFa for periodo ntal disease in a cohort of coronary patients. (PubMed id 22691114)1 Schulz S....Reichert S. (2012)
    1134. Epigenetic regulation of tumor necrosis factor a (TNFa ) release in human macrophages by HIV-1 single-stranded RNA (ssRNA) is dependent on TLR8 signaling. (PubMed id 22393042)1 Han X....Tachado S.D. (2012)
    1135. Mucosal expression of basic fibroblastic growth factor , Syndecan 1 and tumor necrosis factor-alpha in diverticular disease of the colo n: a case-control study. (PubMed id 22680042)1 Tursi A....Ierardi E. (2012)
    1136. Effect of treatment with omega-3 fatty acids on C-reac tive protein and tumor necrosis factor-alfa in hemodialysis patients. (PubMed id 22569435)1 Tayyebi-Khosroshahi H....Zonouz N.R. (2012)
    1137. HIV-1 gp120 and drugs of abuse: interactions in the ce ntral nervous system. (PubMed id 22591361)1 Silverstein P.S....Kumar A. (2012)
    1138. Expression profile of apoptosis-related genes in child hood adrenocortical tumors: low level of expression of BCL2 and TNF genes sugges ts a poor prognosis. (PubMed id 22619347)1 Lorea C.F....Scrideli C.A. (2012)
    1139. Elevation of serum TNF-a levels in mild and moderate A lzheimer patients with daytime sleepiness. (PubMed id 22264991)1 Chen R....Li P. (2012)
    1140. Proinflammatory and 'resiliency' proteins in the CSF of patients with major depression. (PubMed id 21898706)1 Martinez J.M....Gorman J.M. (2012)
    1141. [TNF-a and soluble receptor TNF-a type 1 in children w ith diabetes mellitus type 1]. (PubMed id 22525685)1 Szalecki M....Janas R. (2012)
    1142. Depletion of OLFM4 gene inhibits cell growth and incre ases sensitization to hydrogen peroxide and tumor necrosis factor-alpha induced- apoptosis in gastric cancer cells. (PubMed id 22471589)1 Liu R.H....Huang Y. (2012)
    1143. TNF-a inhibits PPARb/d activity and SIRT1 expression t hrough NF-kB in human adipocytes. (PubMed id 22683888)1 Serrano-Marco L....Vazquez-Carrera M. (2012)
    1144. Lactobacillus plantarum lipoteichoic acid alleviates T NF-a-induced inflammation in the HT-29 intestinal epithelial cell line. (PubMed id 22526394)1 Kim H....Chung D.K. (2012)
    1145. Recognition of human tumor necrosis factor a (TNF-a) b y therapeutic antibody fragment: energetics and structural features. (PubMed id 22262846)1 Marusic J....Lah J. (2012)
    1146. Inhibitory effects of human immunodeficiency virus gp1 20 and Tat on CpG-A-induced inflammatory cytokines in plasmacytoid dendritic cel ls. (PubMed id 22814248)1 Fang M....Yao H. (2012)
    1147. A replicated association between polymorphisms near TN Fa and risk for adverse reactions to radiotherapy. (PubMed id 22767148)1 Talbot C.J....Symonds R.P. (2012)
    1148. Polymorphism G-308A in the promoter of the tumor necro sis factor-a gene and its association with the risk of venous thromboembolism. (PubMed id 22473048)1 Horakova K....Wroblova K. (2012)
    1149. Tumor necrosis factor -308 polymorphism (rs1800629) is associated with mortality and ventilator duration in 1057 Caucasian patients. (PubMed id 22749237)1 Watanabe E....Buchman T.G. (2012)
    1150. Tumor necrosis factor-a -308 G>A and interleukin-6 -174 G>C promoter polymorphisms and pemphigus. (PubMed id 22365967)1 Mosaad Y.M....El-Saied M.A. (2012)
    1151. Guanine-nucleotide exchange factor H1 mediates lipopol ysaccharide-induced interleukin 6 and tumor necrosis factor a expression in endo thelial cells via activation of nuclear factor kB. (PubMed id 22301607)1 Guo F....Huan J. (2012)
    1152. A20 inhibits LUBAC-mediated NF-kB activation by bindin g linear polyubiquitin chains via its zinc finger 7. (PubMed id 23032186)1 Verhelst K....Beyaert R. (2012)
    1153. TLR5, a novel and unidentified inflammatory mediator i n rheumatoid arthritis that correlates with disease activity score and joint TNF -a levels. (PubMed id 22661088)1 Chamberlain N.D....Shahrara S. (2012)
    1154. The role of inflammatory pathway genetic variation on maternal metabolic phenotypes during pregnancy. (PubMed id 22479352)1 Urbanek M....Lowe W.L. (2012)
    1155. Natural killer cell-produced IFN-g and TNF-a induce ta rget cell cytolysis through up-regulation of ICAM-1. (PubMed id 22045868)1 Wang R....Sun P.D. (2012)
    1156. Different susceptibility to insulin resistance and fat ty liver depending on the combination of TNF-a C-857T and adiponectin G+276T gen e polymorphisms in Japanese subjects with type 2 diabetes. (PubMed id 22327199)1 Ohara M....Satoh J. (2012)
    1157. TNF-a, myocardial perfusion and function in patients w ith ST-segment elevation myocardial infarction and primary percutaneous coronary intervention. (PubMed id 22562290)1 Kehmeier E.S....Rassaf T. (2012)
    1158. Tumor necrosis factor a release in peripheral blood mo nonuclear cells of cutaneous lupus and dermatomyositis patients. (PubMed id 22217359)1 Nabatian A.S....Werth V.P. (2012)
    1159. Role of tumor necrosis factor-alpha (C-863A) polymorph ism in pathogenesis of inflammatory bowel disease in Northern India. (PubMed id 21249467)1 Ahirwar D.K....Mittal R.D. (2012)
    1160. Prognostic significance of survivin and tumor necrosis factor-alpha in adult acute lymphoblastic leukemia. (PubMed id 21933669)1 Ahmed M.B....Ibrahim T.M. (2012)
    1161. The association of promoter gene polymorphisms of the tumor necrosis factor-a and interleukin-10 with severity of lactic acidosis duri ng liver transplantation surgery. (PubMed id 22664006)1 Farahat O....Baz H. (2012)
    1162. Genetic variants associated with susceptibility to mot her-to-child transmission of hepatitis B virus. (PubMed id 22772094)1 Chatzidaki V....Galanakis E. (2012)
    1163. Association of hsp70-2 (+1267A/G), hsp70-hom (+2437T/C ), HMOX-1 (number of GT repeats) and TNF-alpha (+489G/A) polymorphisms with COPD in Croatian population. (PubMed id 22542718)1 Matokanovic M....Barisic K. (2012)
    1164. Relative levels of the inflammatory cytokine TNFa and the soluble CD40 ligand profile in serum correlate with the thyrotoxic activity of Graves' disease. (PubMed id 22512415)1 Yamamoto K....Suzuki A. (2012)
    1165. Pivotal role of M-DC8^+ monocytes from viremic HIV-inf ected patients in TNFa overproduction in response to microbial products. (PubMed id 22802339)1 Dutertre C.A....Hosmalin A. (2012)
    1166. Association between TNF-a promoter -308A/G polymorphis m and tardive dyskinesian Chinese Han patients with schizophrenia. (PubMed id 22227290)1 Wang F....Zhang X.Y. (2012)
    1167. Vasoactive intestinal peptide enhances TNF-a-induced I L-6 and IL-8 synthesis in human proximal renal tubular epithelial cells by NF-kB -dependent mechanism. (PubMed id 22207455)1 Huang L....Tao L. (2012)
    1168. Miscarriage, and TNF-a and osteopontin relationship in women patients with Hashimoto's thyroiditis. (PubMed id 22558919)1 Harman E....Yilmaz C. (2012)
    1169. Combination of IL-17 and TNFa induces a pro-inflammato ry, pro-coagulant and pro-thrombotic phenotype in human endothelial cells. (PubMed id 22258491)1 Hot A....Miossec P. (2012)
    1170. Analysis of TNFa promoter SNPs and the risk of cervica l cancer in urban populations of Posadas (Misiones, Argentina). (PubMed id 22019249)1 Badano I....Liotta J.D. (2012)
    1171. Tumor necrosis factor (TNF) and lymphotoxin-alpha (LTA ) single nucleotide polymorphisms: importance in ARDS in septic pediatric critic ally ill patients. (PubMed id 22507624)1 Azevedo Z.M....Moraes M.O. (2012)
    1172. Intestinal epithelial cells with impaired autophagy lo se their adhesive capacity in the presence of TNF-a. (PubMed id 22466076)1 Saito M....Yokosuka O. (2012)
    1173. CD200 positive human mesenchymal stem cells suppress T NF-alpha secretion from CD200 receptor positive macrophage-like cells. (PubMed id 22363701)1 Pietila M....Lehenkari P. (2012)
    1174. Tumor necrosis factor-alpha -308G/A polymorphism and r isk of hepatocellular carcinoma in hepatitis C virus-infected patients. (PubMed id 22200181)1 Talaat R.M....Nasr M.I. (2012)
    1175. Pentoxifylline reduces tumor necrosis factor-a and HIV -induced vascular endothelial activation. (PubMed id 22463742)1 Green L.A....Clauss M. (2012)
    1176. miR-155 modulates TNF-a-inhibited osteogenic different iation by targeting SOCS1 expression. (PubMed id 22634176)1 Wu T....Huang H. (2012)
    1177. High TNF-alpha and IL-8 levels predict low blood dendr itic cell counts in primary cytomegalovirus infection. (PubMed id 22257833)1 Varani S....Soderberg-Naucler C. (2012)
    1178. TNF promoter -308 G>A and LTA 252 A>G polymorphi sms in Portuguese patients with systemic lupus erythematosus. (PubMed id 21544635)1 Santos M.J....Fonseca J.E. (2012)
    1179. Expansion of CD14+CD16+ monocytes producing TNF-a in c omplication-free diabetes type 1 juvenile onset patients. (PubMed id 22484242)1 Mysliwska J....Raczynska K. (2012)
    1180. Molecular targets of the antiinflammatory Harpagophytu m procumbens (devil's claw): inhibition of TNFa and COX-2 gene expression by pre venting activation of AP-1. (PubMed id 22072539)1 Fiebich B.L....McGregor G.P. (2012)
    1181. Tumor necrosis factor alpha 308 G/A polymorphism and G uillain-Barre syndrome risk. (PubMed id 21604171)1 Jiao H....Wang L. (2012)
    1182. The tumour necrosis factor-a-238A allele increases the risk of chronic HBV infection in European populations. (PubMed id 22239507)1 Zheng M.H....Chen Y.P. (2012)
    1183. Selected cytokines and glycodelin A levels in serum an d peritoneal fluid in girls with endometriosis. (PubMed id 22563871)1 Drosdzol-Cop A. and Skrzypulec-Plinta V. (2012)
    1184. Molecular Mechanism of TNFa-Induced Down-Regulation of SHBG Expression. (PubMed id 22301786)1 Simo R....Selva D.M. (2012)
    1185. [Association of the tumor necrosis factor-alpha -1031T /C and its combination with interleukin-6 -634C/G gene polymorphisms with suscep tibility to endometriosis]. (PubMed id 22883518)1 Mao T....Zhu X.N. (2012)
    1186. Association of TNF-a and Fas gene promoter polymorphis m with the risk of Kashin-Beck disease in Northwest Chinese population. (PubMed id 22431252)1 Zhao Q.M....Dang X.Q. (2012)
    1187. Cytokine tumor necrosis factor alpha induces intestina l epithelial barrier dysfunction. (PubMed id 22341723)1 Wang Q.Y....Li C.G. (2012)
    1188. Lack of association between TNF-a gene promoter polymo rphisms and pancreatitis: a meta-analysis. (PubMed id 22579868)1 Yang Z....Fan D. (2012)
    1189. Association of the von Hippel-Lindau protein with AUF1 and posttranscriptional regulation of VEGFA mRNA. (PubMed id 22086907)1 Xin H....Gnarra J.R. (2012)
    1190. Association study between functional polymorphisms in the TNF-alpha gene and obsessive-compulsive disorder. (PubMed id 22311210)1 Cappi C....Hounie A.G. (2012)
    1191. Depth and volume of resorption induced by osteoclasts generated in the presence of RANKL, TNF-alpha/IL-1 or LIGHT. (PubMed id 22172512)1 Mabilleau G....Chappard D. (2012)
    1192. Histamine derived from probiotic Lactobacillus reuteri suppresses TNF via modulation of PKA and ERK signaling. (PubMed id 22384111)1 Thomas C.M....Versalovic J. (2012)
    1193. Variants in the genes encoding TNF-a, IL-10, and GSTP1 influence the effect of a-tocopherol on inflammatory cell responses in healthy men. (PubMed id 22572643)1 England A....Grimble R.F. (2012)
    1194. Association of TNF-a with insulin resistance in type 2 diabetes mellitus. (PubMed id 22382194)1 Swaroop J.J....Naidu J.N. (2012)
    1195. p53 mediates TNF-induced epithelial cell apoptosis in IBD. (PubMed id 22863952)1 Goretsky T....Barrett T.A. (2012)
    1196. Cytokine profile, metabolic syndrome and cardiovascula r disease risk in women with late-onset gestational diabetes mellitus. (PubMed id 22200508)1 Lopez-Tinoco C....Bartha J.L. (2012)
    1197. STAT3 regulates monocyte TNF-alpha production in syste mic inflammation caused by cardiac surgery with cardiopulmonary bypass. (PubMed id 22506067)1 de Jong P.R....Jansen N.J. (2012)
    1198. Associations of cytokine concentrations with key osteo pathic lesions and clinical outcomes in patients with nonspecific chronic low ba ck pain: results from the OSTEOPATHIC Trial. (PubMed id 22984233)1 Licciardone J.C....Bergamini M.V. (2012)
    1199. Prolyl hydroxylase 3 (PHD3) modulates catabolic effect s of tumor necrosis factor-a (TNF-a) on cells of the nucleus pulposus through co -activation of nuclear factor kB (NF-kB)/p65 signaling. (PubMed id 22948157)1 Fujita N....Risbud M.V. (2012)
    1200. Could age modify the effect of genetic variants in IL6 and TNF-a genes in multiple myeloma? (PubMed id 22387051)1 Martino A....Rossi A.M. (2012)
    1201. Association of TNF-a promoter-308 A/G polymorphism wit h susceptibility to systemic lupus erythematosus: a meta-analysis. (PubMed id 21499693)1 Pan H.F....Ye D.Q. (2012)
    1202. Association of TNFa, TNFR1, and TNFR2 polymorphisms wi th sperm concentration and motility. (PubMed id 21350240)1 Lazaros L.A....Georgiou I.A. (2012)
    1203. TNF-a and IL-1RA polymorphisms and silicosis susceptib ility in Chinese workers exposed to silica particles: a case-control study. (PubMed id 23122308)1 Wang Y.W....Kuang J. (2012)
    1204. Time-course network analysis reveals TNF-a can promote G1/S transition of cell cycle in vascular endothelial cells. (PubMed id 22088844)1 Chen Y....Li S. (2012)
    1205. Blastocystis infection is associated with irritable bo wel syndrome in a Mexican patient population. (PubMed id 21870243)