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Aliases for TNDM Gene

Aliases for TNDM Gene

  • Diabetes Mellitus, Transient Neonatal 3
  • TNDM1 3
  • DMTN 3

External Ids for TNDM Gene

Summaries for TNDM Gene

Entrez Gene Summary for TNDM Gene

  • Transient neonatal diabetes mellitus is associated with overexpression of a region containing the PLAGL1 and HYMAI genes on chromosome 6q24. These genes are normally imprinted and expressed only from the paternal allele. Imprinting is regulated by differential methylation of a CpG island in this region. [provided by RefSeq, May 2015]

GeneCards Summary for TNDM Gene

TNDM (Diabetes Mellitus, Transient Neonatal) is an Uncategorized gene. Diseases associated with TNDM include diabetes mellitus, transient neonatal, 1 and paternal uniparental disomy of chromosome 6. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Miscellaneous transport and binding events.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TNDM Gene

Genomics for TNDM Gene

Genomic Location for TNDM Gene

Chromosome:
6
Orientation:
Unknown strand

Genomic View for TNDM Gene

No data available for Regulatory Elements , Cytogenetic band and RefSeq DNA sequence for TNDM Gene

Proteins for TNDM Gene

Post-translational modifications for TNDM Gene

No Post-translational modifications

No data available for DME Specific Peptides for TNDM Gene

Domains & Families for TNDM Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TNDM Gene

Function for TNDM Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TNDM Gene

Localization for TNDM Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TNDM Gene

Pathways & Interactions for TNDM Gene

genes like me logo Genes that share pathways with TNDM: view

Pathways by source for TNDM Gene

Interacting Proteins for TNDM Gene

Gene Ontology (GO) - Biological Process for TNDM Gene

None

No data available for SIGNOR curated interactions for TNDM Gene

Drugs & Compounds for TNDM Gene

No Compound Related Data Available

Expression for TNDM Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TNDM Gene

Orthologs for TNDM Gene

No data available for Orthologs and Evolution for TNDM Gene

Paralogs for TNDM Gene

No data available for Paralogs for TNDM Gene

Variants for TNDM Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for TNDM Gene

Disorders for TNDM Gene

MalaCards: The human disease database

(3) MalaCards diseases for TNDM Gene - From: OMIM and GeneCards

Disorder Aliases PubMed IDs
diabetes mellitus, transient neonatal, 1
  • diabetes mellitus, transient neonatal
paternal uniparental disomy of chromosome 6
  • upd(6)pat
macroglossia
  • congenital macroglossia
- elite association - COSMIC cancer census association via MalaCards
Search TNDM in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with TNDM: view

No data available for UniProtKB/Swiss-Prot , Genatlas and External Links for TNDM Gene

Publications for TNDM Gene

  1. Transient neonatal diabetes mellitus type 1. (PMID: 20803656) Mackay D.J. … Temple I.K. (Am J Med Genet C Semin Med Genet 2010) 3 67
  2. Genetic and epigenetic defects at the 6q24 imprinted locus in a cohort of 13 patients with transient neonatal diabetes: new hypothesis raised by the finding of a unique case with hemizygotic deletion in the critical region. (PMID: 16971482) Diatloff-Zito C. … Robert J.J. (J. Med. Genet. 2007) 3
  3. A maternal hypomethylation syndrome presenting as transient neonatal diabetes mellitus. (PMID: 16816970) Mackay D.J. … Temple I.K. (Hum. Genet. 2006) 3
  4. Bisulphite sequencing of the transient neonatal diabetes mellitus DMR facilitates a novel diagnostic test but reveals no methylation anomalies in patients of unknown aetiology. (PMID: 15635480) Mackay D.J. … Robinson D.O. (Hum. Genet. 2005) 3
  5. Monozygous triplets discordant for transient neonatal diabetes mellitus and for imprinting of the TNDM differentially methylated region. (PMID: 15924231) Kant S.G. … Mackay D.J. (Hum. Genet. 2005) 3

Products for TNDM Gene

Sources for TNDM Gene

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