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Aliases for TMX2-CTNND1 Gene

Subcategory (RNA class) for TMX2-CTNND1 Gene


Quality Score for this RNA gene is


Aliases for TMX2-CTNND1 Gene

  • TMX2-CTNND1 Readthrough (NMD Candidate) 2 3

External Ids for TMX2-CTNND1 Gene

Previous GeneCards Identifiers for TMX2-CTNND1 Gene

  • GC11U901785
  • GC11P057482
  • GC11P057486

Summaries for TMX2-CTNND1 Gene

Entrez Gene Summary for TMX2-CTNND1 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring TMX2 (thioredoxin-related transmembrane protein 2) and CTNND1 (catenin, cadherin-associated protein, delta 1) genes on chromosome 11. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is therefore unlikely to produce a protein product. [provided by RefSeq, Dec 2010]

GeneCards Summary for TMX2-CTNND1 Gene

TMX2-CTNND1 (TMX2-CTNND1 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. An important paralog of this gene is TMX2.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMX2-CTNND1 Gene

Genomics for TMX2-CTNND1 Gene

Genomic Location for TMX2-CTNND1 Gene

57,712,523 bp from pter
57,819,180 bp from pter
106,658 bases
Plus strand

Genomic View for TMX2-CTNND1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for TMX2-CTNND1 Gene

No data available for Regulatory Elements for TMX2-CTNND1 Gene

Proteins for TMX2-CTNND1 Gene

  • Protein details for TMX2-CTNND1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein TMX2-CTNND1
    Protein Accession:

    Protein attributes for TMX2-CTNND1 Gene

    103 amino acids
    Molecular mass:
    11615 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMX2-CTNND1 Gene

Proteomics data for TMX2-CTNND1 Gene at MOPED

Post-translational modifications for TMX2-CTNND1 Gene

No Post-translational modifications

Other Protein References for TMX2-CTNND1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TMX2-CTNND1 Gene

Domains & Families for TMX2-CTNND1 Gene

Protein Domains for TMX2-CTNND1 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMX2-CTNND1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TMX2-CTNND1 Gene

Function for TMX2-CTNND1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMX2-CTNND1 Gene

Localization for TMX2-CTNND1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TMX2-CTNND1 Gene

Pathways & Interactions for TMX2-CTNND1 Gene

SuperPathways for TMX2-CTNND1 Gene

No Data Available

Interacting Proteins for TMX2-CTNND1 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000456881 for TMX2-CTNND1 Gene via STRING

Gene Ontology (GO) - Biological Process for TMX2-CTNND1 Gene


No data available for Pathways by source and SIGNOR curated interactions for TMX2-CTNND1 Gene

Drugs & Compounds for TMX2-CTNND1 Gene

No Compound Related Data Available

Transcripts for TMX2-CTNND1 Gene

mRNA/cDNA for TMX2-CTNND1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TMX2-CTNND1 Gene

No ASD Table

Relevant External Links for TMX2-CTNND1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMX2-CTNND1 Gene

mRNA expression in normal human tissues for TMX2-CTNND1 Gene

genes like me logo Genes that share expression patterns with TMX2-CTNND1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TMX2-CTNND1 Gene

Orthologs for TMX2-CTNND1 Gene

This gene was present in the common ancestor of animals.

Orthologs for TMX2-CTNND1 Gene

Organism Taxonomy Gene Similarity Type Details
(Monodelphis domestica)
Mammalia -- 36
  • 28 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 13 (a)
(Gallus gallus)
Aves -- 36
  • 26 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 27 (a)
(Danio rerio)
Actinopterygii tmx2a 36
  • 18 (a)
tmx2b 36
  • 20 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG11007 36
  • 11 (a)
(Caenorhabditis elegans)
Secernentea C35D10.10 36
  • 10 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5859 36
  • 12 (a)
Species with no ortholog for TMX2-CTNND1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for TMX2-CTNND1 Gene

Gene Tree for TMX2-CTNND1 (if available)
Gene Tree for TMX2-CTNND1 (if available)

Paralogs for TMX2-CTNND1 Gene

Paralogs for TMX2-CTNND1 Gene

(1) SIMAP similar genes for TMX2-CTNND1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TMX2-CTNND1: view

Variants for TMX2-CTNND1 Gene

Sequence variations from dbSNP and Humsavar for TMX2-CTNND1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs501738 -- 57,758,411(-) ATTCA(C/T)TGATT intron-variant
rs507827 -- 57,759,567(-) ttctt(G/T)gggcc intron-variant
rs552122 -- 57,758,328(-) TCACT(A/G)CTCAC intron-variant
rs7949841 -- 57,757,228(+) actct(C/G)tcgcc intron-variant
rs11383661 -- 57,755,541(+) AAGAT(-/T)TTTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMX2-CTNND1 Gene

Variant ID Type Subtype PubMed ID
nsv832163 CNV Gain 17160897
nsv832164 CNV Loss 17160897
nsv508633 CNV Loss 20534489
nsv326 CNV Insertion 18451855
esv2668702 CNV Deletion 23128226
nsv327 CNV Loss 18451855

Relevant External Links for TMX2-CTNND1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TMX2-CTNND1 Gene

Disorders for TMX2-CTNND1 Gene

Relevant External Links for TMX2-CTNND1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with TMX2-CTNND1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMX2-CTNND1 Gene

Publications for TMX2-CTNND1 Gene

  1. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) (Nature 2014) 67
  2. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 67
  3. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9205841) Nagase T. … Ohara O. (DNA Res. 1997) 67

Products for TMX2-CTNND1 Gene

Sources for TMX2-CTNND1 Gene

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