Aliases for TMX2 Gene
External Ids for TMX2 Gene
Previous HGNC Symbols for TMX2 Gene
Previous GeneCards Identifiers for TMX2 Gene
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines. [provided by RefSeq, Jan 2017]
GeneCards Summary for TMX2 Gene
TMX2 (Thioredoxin Related Transmembrane Protein 2) is a Protein Coding gene. An important paralog of this gene is TMX2-CTNND1.