Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMUB1 Gene

protein-coding   GIFtS: 47
GCID: GC07M150778

Transmembrane And Ubiquitin-Like Domain Containing 1

(Previous name: chromosome 7 open reading frame 21)
(Previous symbol: C7orf21)
  Search for TMUB1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transmembrane And Ubiquitin-Like Domain Containing 11 2     DULP2 3
C7orf211 2 3     Chromosome 7 Open Reading Frame 211
Dendritic Cell-Derived Ubiquitin-Like Protein2 3     Transmembrane And Ubiquitin-Like Domain-Containing Protein 12
Hepatocyte Odd Protein Shuttling Protein2 3     Ubiquitin-Like Protein DULP2
Ubiquitin-Like Protein SB1442 3     HOPS3

External Ids:    HGNC: 217091   Entrez Gene: 835902   Ensembl: ENSG000001648977   OMIM: 6147925   UniProtKB: Q9BVT83   

Export aliases for TMUB1 gene to outside databases

Previous GC identifers: GC07M150409 GC07M144590


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TMUB1 Gene: 
TMUB1 (transmembrane and ubiquitin-like domain containing 1) is a protein-coding gene. An important paralog of this gene is TMUB2.

UniProtKB/Swiss-Prot: TMUB1_HUMAN, Q9BVT8
Function: May contribute to the regulation of translation during cell-cycle progression. May contribute to the
regulation of cell proliferation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007914.15  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMUB1 gene promoter:
         GR   GR-beta   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMUB1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TMUB1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMUB1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q36.1   Ensembl cytogenetic band:  7q36.1   HGNC cytogenetic band: 7q36.1

TMUB1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMUB1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M150778:  view genomic region     (about GC identifiers)

Start:
150,778,167 bp from pter      End:
150,780,633 bp from pter
Size:
2,467 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 150,107,712-150,110,158     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TMUB1_HUMAN, Q9BVT8 (See protein sequence)
Recommended Name: Transmembrane and ubiquitin-like domain-containing protein 1  
Size: 246 amino acids; 26261 Da
Subunit: Interacts with EEF1A1 (By similarity)
Subcellular location: Membrane; Multi-pass membrane protein (Potential). Cytoplasm. Nucleus. Note=Predominantly
nuclear during growth arrest (By similarity). Actively exported from the nucleus in dividing cells
Secondary accessions: D3DX06 Q53AQ2

Explore the universe of human proteins at neXtProt for TMUB1: NX_Q9BVT8

Explore proteomics data for TMUB1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BVT8

  • TMUB1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TMUB1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001129516.1  NP_113622.1  

    ENSEMBL proteins: 
     ENSP00000297533   ENSP00000376565   ENSP00000417519   ENSP00000418709   ENSP00000419214  
     ENSP00000420692   ENSP00000420516  

    Human Recombinant Protein Products for TMUB1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Proteins for TMUB1
    OriGene Protein Over-expression Lysate for TMUB1
    OriGene MassSpec for TMUB1 
    OriGene Custom Protein Services for TMUB1
    GenScript Custom Purified and Recombinant Proteins Services for TMUB1
    Novus Biologicals TMUB1 Protein
    Novus Biologicals TMUB1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMUB1 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0016021integral to membrane IEA--

    TMUB1 for ontologies           About GeneDecksing



    TMUB1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TMUB1
    GenScript Custom Superior Antibodies Services for TMUB1
    Novus Biologicals TMUB1 Antibodies
    Abcam antibodies for TMUB1
    Cloud-Clone Corp. Antibodies for TMUB1 
    ThermoFisher Antibodies for TMUB1
    LSBio Antibodies in human, mouse, rat for TMUB1 

    Assay Products for TMUB1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TMUB1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMUB1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMUB1 
    Cloud-Clone Corp. CLIAs for TMUB1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR000626 Ubiquitin
     IPR019955 Ubiquitin_supergroup

    Graphical View of Domain Structure for InterPro Entry Q9BVT8

    ProtoNet protein and cluster: Q9BVT8

    1 Blocks protein domain: IPB000626 Ubiquitin domain

    UniProtKB/Swiss-Prot: TMUB1_HUMAN, Q9BVT8
    Similarity: Contains 1 ubiquitin-like domain


    TMUB1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TMUB1_HUMAN, Q9BVT8
    Function: May contribute to the regulation of translation during cell-cycle progression. May contribute to the
    regulation of cell proliferation (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    TMUB1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for TMUB1:
     Decreased number of cells in m  Increased Salmonella enterica  

         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Tmub1):
     adipose tissue  behavior/neurological  hematopoietic system  immune system 

    TMUB1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Tmub1tm1Lex for TMUB1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for TMUB1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TMUB1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMUB1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMUB1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMUB1
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate TMUB1:
    hsa-miR-27a hsa-miR-128 hsa-miR-3681* hsa-miR-1285 hsa-miR-646 hsa-miR-612 hsa-miR-661 hsa-miR-27b
    SwitchGear 3'UTR luciferase reporter plasmidTMUB1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TMUB1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMUB1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMUB1
    Sirion Biotech Customized adenovirus for overexpression of TMUB1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for TMUB1 (see all 13)
    OriGene ORF clones in mouse, rat for TMUB1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TMUB1 (NM_001136044)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMUB1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMUB1
    Sirion Biotech Customized lentivirus for stable overexpression of TMUB1 
                         Customized lentivirus expression plasmids for stable overexpression of TMUB1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMUB1
    Search LifeMap BioReagents cell lines for TMUB1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMUB1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMUB1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/6 Interacting proteins for TMUB1 (Q9BVT83 ENSP000002975334) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AMFRQ9UKV53, ENSP000002906494I2D: score=1 STRING: ENSP00000290649
    ERLIN2O949053, ENSP000002764614I2D: score=1 STRING: ENSP00000276461
    RNF139Q8WU173, ENSP000003040514I2D: score=1 STRING: ENSP00000304051
    SYVN1Q86TM63, ENSP000003663954I2D: score=1 STRING: ENSP00000366395
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TMUB1

    Search CenterWatch for drugs/clinical trials and news about TMUB1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TMUB1 gene (2 alternative transcripts): 
    NM_001136044.1  NM_031434.3  

    Unigene Cluster for TMUB1:

    Transmembrane and ubiquitin-like domain containing 1
    Hs.726215  [show with all ESTs]
    Unigene Representative Sequence: NM_031434
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000297533(uc003wjd.3) ENST00000392818(uc003wjc.3) ENST00000462940(uc003wjb.3)
    ENST00000482202 ENST00000476627 ENST00000488752 ENST00000492838
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMUB1
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate TMUB1:
    hsa-miR-27a hsa-miR-128 hsa-miR-3681* hsa-miR-1285 hsa-miR-646 hsa-miR-612 hsa-miR-661 hsa-miR-27b
    SwitchGear 3'UTR luciferase reporter plasmidTMUB1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TMUB1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMUB1
    Clone
    Products:
         
    OriGene clones in human, mouse for TMUB1 (see all 13)
    OriGene ORF clones in mouse, rat for TMUB1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TMUB1 (NM_001136044)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMUB1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMUB1
    Sirion Biotech Customized lentivirus for stable overexpression of TMUB1 
                         Customized lentivirus expression plasmids for stable overexpression of TMUB1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMUB1
    OriGene qSTAR qPCR primer pairs in human, mouse for TMUB1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMUB1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMUB1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMUB1

    Additional mRNA sequence: 

    AK314035.1 AY037155.1 AY358481.1 AY603380.1 BC000936.1 BC033182.1 

    13 DOTS entries:

    DT.111352  DT.92437033  DT.92437031  DT.95188413  DT.100818438  DT.100818435  DT.100818443  DT.99926386 
    DT.95188388  DT.97847803  DT.100818436  DT.100818440  DT.100844948 

    24/631 AceView cDNA sequences (see all 631):

    BC000377 BM552664 BM705064 CF134787 BM693823 BU634380 BM142075 CR619155 
    BQ223605 BQ679755 BM314521 BM547737 BM844796 BC033182 CR590845 AA251816 
    BM824050 BF446329 BX464935 BC011770 BI824094 CR617191 BM052908 BQ677384 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for TMUB1 (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6a · 6b · 6c ^ 7a · 7b · 7c
    SP1:        -     -     -     -     -     -     -     -                                 
    SP2:              -     -     -     -     -     -     -                                 
    SP3:                    -     -     -     -     -     -                                 
    SP4:                          -     -     -     -     -                                 
    SP5:                                                  -     -                           


    ECgene alternative splicing isoforms for TMUB1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TMUB1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACCGCCCGT
    TMUB1 Expression
    About this image


    See TMUB1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TMUB1

    SOURCE GeneReport for Unigene cluster: Hs.726215
        SABiosciences Custom PCR Arrays for TMUB1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TMUB1
    OriGene qSTAR qPCR primer pairs in human, mouse for TMUB1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMUB1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMUB1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMUB1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMUB1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TMUB1 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmub11 , 5 transmembrane and ubiquitin-like domain containing more1, 5 87.48(n)1
    89.8(a)1
      5 (11.79 cM)5
    642951  NM_022418.31  NP_071863.11 
     244454585 
    chicken
    (Gallus gallus)
    Aves TMUB11 transmembrane and ubiquitin-like domain containing more 70.86(n)
    60.84(a)
      431107  XM_428658.3  XP_428658.3 
    lizard
    (Anolis carolinensis)
    Reptilia TMUB16
    Uncharacterized protein
    41(a)
    1 ↔ 1
    AAWZ02040777(21-6444)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.117602 Transcribed sequence with weak similarity to protein more 71.72(n)    BX699569.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa98b102 Transcribed sequence with weak similarity to protein more 71.57(n)    CK027052.1 
    worm
    (Caenorhabditis elegans)
    Secernentea B0303.46
    Uncharacterized protein B0303.4
    10(a)
    1 → many
    III(8689850-8693473)


    ENSEMBL Gene Tree for TMUB1 (if available)
    TreeFam Gene Tree for TMUB1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TMUB1 gene
    TMUB22  
    1 SIMAP similar gene for TMUB1 using alignment to 3 protein entries:     TMUB1_HUMAN (see all proteins):
    TMUB2

    TMUB1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/29 SNPs in TMUB1 are shown (see all 29)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1897954291,2
    --150779989(+) TTCACC/TCCAAC 2 -- int1 ut510--------
    rs1824397801,2
    --150780169(+) CCCCAC/TCCGCG 2 -- int1 ut510--------
    rs1879630731,2
    --150780245(+) GCCACC/TGAGCG 2 -- int1 ut510--------
    rs1910093191,2
    --150780436(+) GCCCCC/TCGAAG 2 -- int1 us2k10--------
    rs1439825501,2
    C--150780530(+) CGGCTC/TCCCCA 2 -- ut51 us2k10--------
    rs1464702341,2
    --150780600(+) AAGCAA/CCCCTC 2 -- ut51 us2k10--------
    rs1509857261,2
    C--150780747(+) GGGGC-/GGGTTT 2 -- us2k10--------
    rs1834238861,2
    --150780768(+) GCTACC/TCCCTA 2 -- us2k10--------
    rs69621001,2
    C,H--150780933(+) TGTCAG/CAGTGG 2 -- us2k115Minor allele frequency- C:0.00NS EA NA WA CSA 669
    rs1873478581,2
    --150780978(+) CTTCAA/GCCCAG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TMUB1 (150778167 - 150780633 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for TMUB1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv6004CNV Insertion18451855
    dgv7547n71CNV Loss21882294
    dgv7546n71CNV Loss21882294
    dgv7548n71CNV Loss21882294
    nsv889477CNV Loss21882294
    nsv465215CNV Loss19166990
    nsv889465CNV Loss21882294
    dgv7545n71CNV Loss21882294
    nsv831188CNV Loss17160897
    nsv889476CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing TMUB1
    DNA2.0 Custom Variant and Variant Library Synthesis for TMUB1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TMUB1 for disorders           About MalaCards
    OMIM gene information: 614792    OMIM disorders: --


    TMUB1 for disorders           About GeneDecksing


    Export disorders for TMUB1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TMUB1 gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with TMUB1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of DULP, a novel ubiquitin-like molecule from human dendritic cells. (PubMed id 19254477)1, 2 Liu G.Y.... Yu Y.Z. (2009)
    2. HOPS: a novel cAMP-dependent shuttling protein involved in protein synthesis regulation. (PubMed id 16014383)1, 2 Della Fazia M.A.... Servillo G. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    5. Novel, gel-free proteomics approach identifies RNF5 an d JAMP as modulators of GPCR stability. (PubMed id 23798571)1 Roy S.J....Parent J.L. (2013)
    6. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    10. Membrane-associated ubiquitin ligase complex containi ng gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-c oenzyme A reductase. (PubMed id 21343306)1 Jo Y....DeBose-Boyd R.A. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83590 HGNC: 21709 AceView: FASTKandC7orf21 Ensembl:ENSG00000164897 euGenes: HUgn83590
    ECgene: TMUB1 H-InvDB: TMUB1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMUB1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TMUB1 gene:
    Search GeneIP for patents involving TMUB1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMUB1  
     OriGene qPCR primer pairs and template standards for TMUB1   OriGene Protein Over-expression Lysate for TMUB1  
     OriGene MassSpec something-or-other for TMUB1   OriGene clones in human, mouse for TMUB1  
     OriGene qSTAR qPCR primer pairs in human, mouse for TMUB1   OriGene Purified Protein for TMUB1  
     OriGene ORF clones in mouse, rat for TMUB1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TMUB1   OriGene Custom Protein Services for TMUB1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TMUB1
     QIAGEN SeqTarget long-range PCR primers for resequencing TMUB1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMUB1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMUB1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMUB1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMUB1
     GenScript Custom Purified and Recombinant Proteins Services for TMUB1 GenScript cDNA clones with any tag delivered in your preferred vector for TMUB1
     GenScript Custom Assay Services for TMUB1 GenScript Custom Superior Antibodies Services for TMUB1
     GenScript Custom overexpressing Cell Line Services for TMUB1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in TMUB1 promoter
     Search Chromatin IP Primers for TMUB1
     RT2 qPCR Primer Assay in human, mouse, rat TMUB1
     Search GNC Networks for TMUB1
     SABiosciences Custom PCR Arrays for TMUB1
     Search Tocris compounds for TMUB1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     TMUB1 antibodies
     TMUB1 proteins
     TMUB1 lysates
     Antibodies for TMUB1
     See all of Abcam's Antibodies, Kits and Proteins for TMUB1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for TMUB1
     Antibodies for TMUB1
     ELISAs for TMUB1
     CLIAs for TMUB1
     Search LifeMap BioReagents cell lines for TMUB1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMUB1
     SwitchGear 3'UTR luciferase reporter plasmids for TMUB1
     SwitchGear Promoter luciferase reporter plasmids for TMUB1
     ThermoFisher Antibodies for TMUB1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMUB1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for TMUB1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TMUB1
    Customized:
     lentivirus for stable overexpression of TMUB1
     lentivirus expression plasmids for stable overexpression of TMUB1
     adenovirus for overexpression of TMUB1
     LSBio Antibodies in human, mouse, rat for TMUB1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TMUB1 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4