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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMTC2 Gene

protein-coding   GIFtS: 49
GCID: GC12P083080

Transmembrane And Tetratricopeptide Repeat Containing 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transmembrane And Tetratricopeptide Repeat Containing 21 2
IBDBP12
IBDBP1 Transcript 22
IBDBP1, Transcript 12
Transmembrane And TPR Repeat-Containing Protein 22

External Ids:    HGNC: 254401   Entrez Gene: 1603352   Ensembl: ENSG000001791047   UniProtKB: Q8N3943   

Export aliases for TMTC2 gene to outside databases

Previous GC identifers: GC12P081584 GC12P080139


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TMTC2 Gene: 
TMTC2 (transmembrane and tetratricopeptide repeat containing 2) is a protein-coding gene. Diseases associated with TMTC2 include primary open angle glaucoma, and open-angle glaucoma. An important paralog of this gene is TMTC3.

Gene Wiki entry for TMTC2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_029419.12  NC_018923.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMTC2 gene promoter:
         Max1   POU3F1   MyoD   HNF-3beta   S8   NF-kappaB2   TGIF   NF-kappaB1   Hlf   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMTC2 promoter sequence
   Search SABiosciences Chromatin IP Primers for TMTC2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMTC2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q21.31   Ensembl cytogenetic band:  12q21.31   HGNC cytogenetic band: 12q21.31

TMTC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMTC2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P083080:  view genomic region     (about GC identifiers)

Start:
83,080,659 bp from pter      End:
83,528,649 bp from pter
Size:
447,991 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TMTC2_HUMAN, Q8N394 (See protein sequence)
Recommended Name: Transmembrane and TPR repeat-containing protein 2  
Size: 836 amino acids; 94130 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=BAC11102.1; Type=Erroneous initiation;
Secondary accessions: B2RCU7 Q8N2K8

Explore the universe of human proteins at neXtProt for TMTC2: NX_Q8N394

Explore proteomics data for TMTC2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N394

  • TMTC2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TMTC2 Protein Expression
    REFSEQ proteins: NP_689801.1  
    ENSEMBL proteins: 
     ENSP00000322300   ENSP00000448292   ENSP00000448630   ENSP00000447609  

    Human Recombinant Protein Products for TMTC2: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMTC2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum IDA--
    GO:0016021integral to membrane IEA--

    TMTC2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TTC: Tetratricopeptide (TTC) repeat domain containing

    4 InterPro protein domains:
     IPR011990 TPR-like_helical
     IPR013618 DUF1736
     IPR013026 TPR-contain_dom
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry Q8N394

    ProtoNet protein and cluster: Q8N394

    UniProtKB/Swiss-Prot: TMTC2_HUMAN, Q8N394
    Similarity: Belongs to the TMTC family
    Similarity: Contains 10 TPR repeats


    TMTC2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0042802identical protein binding ----
         
    TMTC2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TMTC2 
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    miRNA
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    8/27 QIAGEN miScript miRNA Assays for microRNAs that regulate TMTC2 (see all 27):
    hsa-miR-520e hsa-miR-302d hsa-miR-3660 hsa-miR-128 hsa-miR-302e hsa-miR-342-3p hsa-miR-519a hsa-miR-29b-1*
    SwitchGear 3'UTR luciferase reporter plasmidTMTC2 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMTC2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMTC2

    1 Interacting protein for TMTC2 (Q8N3943) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SUFUQ9UMX13I2D: score=4 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TMTC2

    Search CenterWatch for drugs/clinical trials and news about TMTC2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TMTC2 gene: 
    NM_152588.1  

    Unigene Cluster for TMTC2:

    Transmembrane and tetratricopeptide repeat containing 2
    Hs.577775  [show with all ESTs]
    Unigene Representative Sequence: AL834509
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000551915(uc001szs.1) ENST00000321196(uc001szt.3 uc010suk.2)
    ENST00000548305(uc001szr.1) ENST00000546590 ENST00000549919
    miRNA
    Products:
         
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    8/27 QIAGEN miScript miRNA Assays for microRNAs that regulate TMTC2 (see all 27):
    hsa-miR-520e hsa-miR-302d hsa-miR-3660 hsa-miR-128 hsa-miR-302e hsa-miR-342-3p hsa-miR-519a hsa-miR-29b-1*
    SwitchGear 3'UTR luciferase reporter plasmidTMTC2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TMTC2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMTC2
    Clone
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    OriGene clones in human, mouse for TMTC2 (see all 7)
    OriGene ORF clones in mouse, rat for TMTC2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMTC2 (NM_152588)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMTC2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMTC2
    Sirion Biotech Customized lentivirus for stable overexpression of TMTC2 
                         Customized lentivirus expression plasmids for stable overexpression of TMTC2 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMTC2
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    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMTC2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMTC2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMTC2

    Additional mRNA sequence: 

    AK074634.1 AK299771.1 AK315285.1 AL834509.1 BC047464.1 BC071614.1 BC093852.1 BC093854.1 
    BC098572.1 BC143378.1 

    9 DOTS entries:

    DT.111236  DT.439058  DT.91758558  DT.121175842  DT.121175919  DT.121175929  DT.75149634  DT.95256094 
    DT.97806648 

    24/45 AceView cDNA sequences (see all 45):

    NM_152588 BU735946 AW474234 CA424966 AI886513 AX795396 AL834509 AI350781 
    AI537287 AX795392 BM697269 AK074634 AX795394 BP357360 AV726517 BF002762 
    N51813 CO246142 AI262660 BC071614 BC047464 AI765006 BX508970 BX641525 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TMTC2 expression in normal human tissues (normalized intensities)      TMTC2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCAAAAAAT
    TMTC2 Expression
    About this image


    TMTC2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/17 selected tissues (see all 17) fully expand
     
     Brain (Nervous System)    fully expand to see all 5 entries
             ganglion/cranial/facial VII   
     
     Limb (Muscoskeletal System)    fully expand to see all 5 entries
             Autopod
             limb/hindlimb/leg   
     
     Eye (Sensory Organs)    fully expand to see all 3 entries
             nGnG Amacrine Cells Inner Nuclear Layer
             Retina
             sensory organ/eye/cornea   
     
     Lower Urinary Tract (Urinary System)    fully expand to see all 3 entries
             Ureter
             visceral organ/bladder   
     
     Gut Tube (Gastrointestinal Tract)    fully expand to see all 3 entries
             Hindgut

    See TMTC2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TMTC2

    SOURCE GeneReport for Unigene cluster: Hs.577775
        SABiosciences Custom PCR Arrays for TMTC2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMTC2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TMTC2 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmtc21 , 5 transmembrane and tetratricopeptide repeat containing more1, 5 88.8(n)1
    95.69(a)1
      10 (54.72 cM)5
    2782791  NM_177368.41  NP_796342.21 
     1051876635 
    chicken
    (Gallus gallus)
    Aves TMTC21 transmembrane and tetratricopeptide repeat containing more 81.27(n)
    87.13(a)
      417880  XM_416123.3  XP_416123.3 
    lizard
    (Anolis carolinensis)
    Reptilia TMTC26
    Uncharacterized protein
    83(a)
    1 ↔ 1
    5(35994402-36120451)
    zebrafish
    (Danio rerio)
    Actinopterygii tmtc21 transmembrane and tetratricopeptide repeat containing more 66.51(n)
    71.86(a)
      564667  NM_001130603.1  NP_001124075.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG43411 CG4341 47.67(n)
    42.5(a)
      33276  NM_134714.4  NP_608558.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F32D1.31 Protein F32D1.3 43.38(n)
    35.89(a)
      178832  NM_071799.2  NP_504200.1 


    ENSEMBL Gene Tree for TMTC2 (if available)
    TreeFam Gene Tree for TMTC2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TMTC2 gene
    TMTC32  TMTC12  OGT2  TMTC42  
    3 SIMAP similar genes for TMTC2 using alignment to 3 protein entries:     TMTC2_HUMAN (see all proteins):
    TMTC1    TMTC3    TMTC4

    TMTC2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/9310 SNPs in TMTC2 are shown (see all 9310)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs57995981,2
    C--80349525(+) ATATA-/TAAAGAC 1 -- int11Minor allele frequency- TA:0.00NA 2
    rs341380591,2
    C--82950570(+) TTTTT-/TCTTAT 1 -- int10--------
    rs1492160581,2
    --83078935(+) TATTTC/TACATA 1 -- us2k10--------
    rs780355821,2
    C,F--83078950(+) AACTAC/TTTTAA 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1808540761,2
    --83079098(+) AAACAA/TCTGAT 1 -- us2k10--------
    rs1402007091,2
    C--83079119(+) GTGTT-/CTTCCT 1 -- us2k10--------
    rs746429751,2
    F--83079162(+) TATATA/GCTATA 1 -- us2k11Minor allele frequency- G:0.08WA 118
    rs760061011,2
    F--83079264(+) TATGGA/GGGAAA 1 -- us2k11Minor allele frequency- G:0.01WA 118
    rs1849222141,2
    --83079673(+) CATCGC/TGGTGC 1 -- us2k10--------
    rs1451773471,2
    --83079698(+) CCTGGA/CCAGAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TMTC2 (83080659 - 83330659 bp, first 250kb of TMTC2)

    Structural Variations
         Database of Genomic Variants (DGV) 10/36 variations for TMTC2 (see all 36):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1003105CNV Deletion20482838
    esv2746123CNV Deletion23290073
    esv2746125CNV Deletion23290073
    esv2016291CNV Deletion18987734
    esv2421910CNV Deletion20811451
    esv2663704CNV Deletion23128226
    esv2746126CNV Deletion23290073
    esv5126CNV Deletion18987735
    esv2746124CNV Deletion23290073
    nsv507662CNV Insertion20534489

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TMTC2
    DNA2.0 Custom Variant and Variant Library Synthesis for TMTC2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    4 diseases for TMTC2:    About MalaCards
    primary open angle glaucoma    open-angle glaucoma    glaucoma    hypoxia

    1 disease from the University of Copenhagen DISEASES database for TMTC2:
    Primary open angle glaucoma

    TMTC2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TMTC2
    Human Genome Epidemiology (HuGE) Navigator: TMTC2 (4 documents)

    Export disorders for TMTC2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TMTC2 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with TMTC2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A genome-wide search for loci interacting with known p rostate cancer risk-associated genetic variants. (PubMed id 22219177)1, 4 Tao S....Sun J. (2012)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. Three susceptible loci associated with primary open-a ngle glaucoma identified by genome-wide association study in a Japanese populat ion. (PubMed id 19625618)1, 4 Nakano M....Tashiro K. (2009)
    4. Molecular genetics of successful smoking cessation: convergent genome-wide association study results. (PubMed id 18519826)1, 4 Uhl G.R....Lerman C. (2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Genome-wide association study of antibody response to smallpox vaccine. (PubMed id 22542470)1 Ovsyannikova I.G....Poland G.A. (2012)
    8. Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus. (PubMed id 20662065)1 Clancy R.M....Buyon J.P. (2010)
    9. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    10. Genome-wide association of hypoxia-inducible factor ( HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-ind ucible transcripts. (PubMed id 19386601)1 Mole D.R....Ratcliffe P.J. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 160335 HGNC: 25440 AceView: DKFZp762A217 Ensembl:ENSG00000179104 euGenes: HUgn160335
    ECgene: TMTC2 H-InvDB: TMTC2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMTC2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TMTC2 gene:
    Search GeneIP for patents involving TMTC2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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