Aliases for TMTC2 Gene
External Ids for TMTC2 Gene
Previous GeneCards Identifiers for TMTC2 Gene
The protein encoded by this gene is an integral membrane protein localized to the endoplasmic reticulum (ER). The encoded protein contains many tetratricopeptide repeats, sequences known for being involved in protein-protein interactions. This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin, and it appears to play a role in calcium homeostasis in the ER. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
GeneCards Summary for TMTC2 Gene
TMTC2 (Transmembrane And Tetratricopeptide Repeat Containing 2) is a Protein Coding gene. Diseases associated with TMTC2 include Open-Angle Glaucoma and Glaucoma 1, Open Angle, E. GO annotations related to this gene include identical protein binding. An important paralog of this gene is TMTC1.