TMSB4X Gene
protein-coding GIFtS: 54
GCID: GC0XP012993
|
|
thymosin beta 4, X-linked(Previous names: thymosin, beta 4, X chromosome )
(Previous symbol: TMSB4)
| |
Aliases
for TMSB4X gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Thymosin Beta 4, X-Linked1 2 | | FX2 | | TB4X1 2 3 5 | | Prothymosin Beta-42 | | TMSB41 2 3 5 | | Thymosin Beta-42 | | Thymosin, Beta 4, X Chromosome1 2 | | Fx3 | | T Beta-42 3 | | THYB43 | | PTMB42 5 | | |
Export aliases for TMSB4X gene to outside databasesPrevious GC identifers: GC04M091917 GC04M092061 GC0XP012354 GC0XP012752 GC0XP012903 GC0XP010756 |
Summaries
for TMSB4X gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TMSB4X:
This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The proteinis also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has ahomolog on chromosome Y. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: TYB4_HUMAN, P62328Function: Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequestersactin monomers (G actin) and therefore inhibits actin polymerizationFunction: Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase (By similarity)
Gene Wiki entry for TMSB4X (Thymosin beta-4)
|
Genomic Views
for TMSB4X gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_167197.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TMSB4X gene promoter:
PPAR-gamma1 AP-1 ATF-2 c-Jun PPAR-gamma2 NF-kappaB1 NF-kappaB
Other transcription factors
Search SABiosciences Chromatin IP Primers for TMSB4X
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMSB4X |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq21.3-q22 Ensembl cytogenetic band: Xp22.2 HGNC cytogenetic band: Xq21.3-q22TMSB4X Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP012993: view genomic region
(about GC identifiers)
Start:
|
12,993,226 bp from pter |
End:
|
12,995,346 bp from pter |
Size:
|
2,121 bases |
Orientation:
|
plus strand |
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Proteins
for TMSB4X gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TYB4_HUMAN, P62328 (See
protein sequence)Recommended Name: Thymosin beta-4 Size: 44 amino acids; 5053 Da
Subcellular location: Cytoplasm, cytoskeleton
2 PDB 3D structures from  and Proteopedia  for TMSB4X:1UY5 (3D)
3TU5 (3D)
Secondary accessions: P01253 P01254 Q546P5 Q63576 Q9UE55Explore the universe of human proteins at neXtProt for TMSB4X: NX_P62328
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P62328
TMSB4X Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_066932.1
ENSEMBL proteins: ENSP00000414376 ENSP00000370010 ENSP00000370009 ENSP00000370007 Reactome Protein details: P62328
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
TMSB4X for ontologies About GeneDecksing
TMSB4X Antibody Products:
Assay Products for TMSB4X: |
Protein
Domains /
Families
for TMSB4X gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TMSB4X for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P62328ProtoNet protein and cluster: P62328 UniProtKB/Swiss-Prot: TYB4_HUMAN, P62328Similarity: Belongs to the thymosin beta family |
Function
for TMSB4X gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TYB4_HUMAN, P62328Function: Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequestersactin monomers (G actin) and therefore inhibits actin polymerizationFunction: Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase (By similarity)Induction: By alpha interferons. Decreased levels in THP-1 cells after treatment with recombinant interferon-lambda Genatlas biochemistry entry for TMSB4X:thymosin beta 4,identical to the interferon inducible gene 6-26 (4/6-26)-like 7,potential actin sequesteringprotein,escaping inactivation,ubiquitous
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMSB4X (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMSB4X
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TMSB4X (NM_021109) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMSB4X | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMSB4X |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003779 | actin binding |
IEA | -- | | GO:0005515 | protein binding |
IPI | -- |
TMSB4X for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Tmsb4xtm1.1Chen for TMSB4X
2 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Tmsb4x):
TMSB4X for phenotypes About GeneDecksing
|
Pathways & Interactions
for TMSB4X gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Platelet activation, signaling and aggregation | | | 2 | Platelet degranulation | | | 3 | Regulation of Actin Cytoskeleton | | | 4 | Rho Family GTPases | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for TMSB4X
1  BioSystems Pathway for TMSB4X
4 
Reactome Pathways for TMSB4X
1 
Kegg Pathway (Kegg details for TMSB4X):
TMSB4X for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TMSB4X
STRING Interaction
Network Preview (showing 5 interactants - click image to see 13)
5/29 Interacting proteins for TMSB4X (P623281, 2, 3 ENSP000003700074) via UniProtKB, MINT, STRING, and/or I2D (see all 29)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
TMSB4X for ontologies About GeneDecksing
|
Drugs & Compounds
for TMSB4X gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
TMSB4X for compounds About GeneDecksing
 Browse Tocris compounds for TMSB4X
10/17 Novoseek chemical compound relationships for TMSB4X gene (see all 17) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tetrapeptide |
66.6 |
3 |
12916639 (1), 17191900 (1), 2253778 (1) |
| matrigel |
37.6 |
3 |
8719875 (2), 16423999 (1) |
| phalloidin |
37 |
2 |
8055911 (2) |
| perchloric acid |
23.8 |
1 |
2209614 (1) |
| lysine |
18 |
1 |
18327913 (1) |
| cytarabine |
14.4 |
1 |
12962156 (1) |
| atp |
11.3 |
9 |
14623892 (2), 8506348 (1), 8576116 (1), 8055911 (1) (see all 7) |
| methionine |
6.64 |
1 |
9563520 (1) |
| adp |
4.43 |
4 |
8506348 (1), 10940259 (1), 8055911 (1), 7787248 (1) |
| fibrinogen |
1.27 |
4 |
17892513 (2), 8514613 (1) |
Search CenterWatch for drugs/clinical trials and news about TMSB4X / TYB4
|
Transcripts
for TMSB4X gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TMSB4X gene: NM_021109.3 Unigene Cluster for TMSB4X: Thymosin beta 4, X-linked Hs.437277 [show with all ESTs]Unigene Representative Sequence: BF6805124 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000451311(uc004cvf.3) ENST00000380636 ENST00000380635 ENST00000380633
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMSB4X (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMSB4X
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TMSB4X (NM_021109) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMSB4X | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMSB4X |
Additional cDNA sequence: AK055976.1 AK057827.1 AK311747.1 BC001631.1 BC016732.1 BC022857.1 BC061586.1 BC062436.1 BC064954.1 BC070248.1 BC070249.1 BC083509.1 BC092437.1 BC101790.1 BC101792.1 BC104464.1 BC104465.1 BC104666.1 BC107789.1 BC128102.1 BC128103.1 BC139925.1 BC141975.1 BC141976.1 BC151215.1 BT007090.1 M11948.1 M17733.1 X02493.1 24/109 DOTS entries (see all 109): DT.95377392 DT.100741234 DT.100741255 DT.100741263 DT.92471804 DT.100741219 DT.92471824 DT.121313106 DT.95377459 DT.100741220 DT.100060434 DT.85101298 DT.100867513 DT.100741218 DT.91910729 DT.95335616 DT.100741252 DT.100741239 DT.91981905 DT.91820572 DT.100741257 DT.100741227 DT.121313016 DT.121313144 24/4052 AceView cDNA sequences (see all 4052): BM836350 AA374732 AA360643 AI954979 H83682 AA620438 AA363783 AI086957 BM766282 BM838367 BQ269663 BI438491 BM836233 BM990152 BM838806 AA360681 AA132113 AL048571 BM818261 AW574637 CA431403 BM833704 AI917254 AI708544
GeneLoc Exon Structure
|
Expression
for TMSB4X gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TMSB4X expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGGTGAAGG
About this image
See TMSB4X Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TMSB4X
SOURCE GeneReport for Unigene cluster: Hs.437277
UniProtKB/Swiss-Prot: TYB4_HUMAN, P62328Tissue specificity: Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels inmyeloma cells
SABiosciences Custom PCR Arrays for TMSB4X
Primer
Products: | | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat TMSB4X | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMSB4X | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMSB4X |
Orthologs
for TMSB4X gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for TMSB4X gene from 4/9 species (see all 9) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
TMSB106 |
Uncharacterized protein |
83(a) |
1 → many |
13(14578839-14579804) |
lizard
(Anolis carolinensis) |
Reptilia |
TMSL46 |
-- |
100(a) |
1 → many |
3(120076424-120076936) |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.125592 |
Transcribed sequence with moderate similarity to protein more |
73.83(n) |
|
CF999620.1 |
soybean
(Glycine max) |
eudicotyledons |
445109412 |
-- |
87.29(n) |
|
|
ENSEMBL Gene Tree for TMSB4X (if available)
TreeFam Gene Tree for TMSB4X (if available) |
Paralogs
for TMSB4X gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TMSB4X gene
- TMSB15B2 TMSB15A2 TMSB4Y2 TMSB4XP42 TMSB102
5 SIMAP similar genes for TMSB4X using alignment to 7 protein entries: TYB4_HUMAN (see all proteins):TMSB15A TMSB4XP4 TMSB4Y TMSB10 TMSB15B
TMSB4X for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for TMSB4X
PGOHUM00000262015
|
Genomic Variants
for TMSB4X gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TMSB4X (12993226 - 12995346 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TMSB4X: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMSB4X |
|
Disorders
/ Diseases
for TMSB4X gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TMSB4X for disorders About GeneDecksing
OMIM gene information: 300159
OMIM disorders: --
20/40  diseases for TMSB4X (see all 40): About MalaCardsvernal keratoconjunctivitis epidermolysis bullosa x inactivation ischemic heart disease
keratoconjunctivitis interstitial lung disease rheumatoid arthritis, association with rheumatoid arthritis
thymoma diabetic retinopathy fibrosarcoma renal cell carcinoma
cystic fibrosis colon carcinoma gigantism colon cancer
keloids genetic disease hepatitis b scleroderma
10/20 Novoseek disease relationships for TMSB4X gene (see all 20) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| b-all |
36.5 |
1 |
9477130 (1) |
| colorectal carcinoma |
28.8 |
1 |
17072345 (1) |
| fibrosarcoma |
25.8 |
1 |
19405119 (1) |
| thymoma |
22.3 |
1 |
2333664 (1) |
| scar |
14.6 |
3 |
15698487 (1) |
| tumors |
14.4 |
36 |
16949646 (4), 20353910 (3), 17495241 (3), 2043590 (2) (see all 21) |
| colon carcinoma |
11.6 |
1 |
16364925 (1) |
| metastasis |
11 |
9 |
12970751 (2), 16956606 (1), 17923415 (1), 17916567 (1) (see all 8) |
| inflammation |
3.07 |
4 |
16630613 (1), 17200658 (1), 17083265 (1), 12358412 (1) |
| colon cancer |
1.12 |
3 |
16501890 (1), 17072345 (1), 16364925 (1) |
Genetic Association Database (GAD): TMSB4X
Export disorders for TMSB4X gene to outside databases
|
Publications
for TMSB4X gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TMSB4X gene, integrated from 9 sources (see all 200):
(articles sorted by number of sources associating them with TMSB4X) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Thymosin beta 4 and Fx, an actin-sequestering peptide, are indistinguishable. (PubMed id 1999398)1, 2, 9 Safer D.... Nachmias V.T. (1991)
- Structural requirements for thymosin beta4 in its contact with actin. An NMR-analysis of thymosin beta4 mutants in solution and correlation with their biological activity. (PubMed id 10848969)1, 2, 9 Simenel C.... Delepierre M. (2000)
- Molecular cloning and structural characterization of the functional human thymosin beta4 gene. (PubMed id 16010977)1, 2 Yang S.P.... Su Y. (2005)
- Functional coherence of the human Y chromosome. (PubMed id 9381176)1, 3 Lahn B.T. and Page D.C. (1997)
- Thymosin-beta 4 gene. Preliminary characterization and expression in tissues, thymic cells, and lymphocytes. (PubMed id 2677145)1, 3 Gomez-Marquez J....Freire M. (1989)
- Differential expression of the human thymosin-beta 4 gene in lymphocytes, macrophages, and granulocytes. (PubMed id 3500230)1, 2 Gondo H....Saunders G.F. (1987)
- Transcriptional and posttranscriptional regulation of interferon- induced gene expression in human cells. (PubMed id 6548414)1, 2 Friedman R.L.... Stark G.R. (1984)
- Thymosin beta 4 binds actin in an extended conformation and contacts both the barbed and pointed ends. (PubMed id 9153421)1, 9 Safer D....Elzinga M. (1997)
- Occurrence of thymosin beta4 in human breast cancer cells and in other cell types of the tumor microenvironment. (PubMed id 16949646)1, 9 Larsson L.I. and Holck S. (2007)
- Reduction of thymosin beta4 and actin in HL60 cells during apoptosis is preceded by a decrease of their mRNAs. (PubMed id 12962156)1, 9 Muller C.S....Hannappel E. (2003)
|
External Searches for TMSB4X gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TMSB4X gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TMSB4X gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TMSB4X gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for TMSB4X gene:
Search GeneIP for patents involving TMSB4X
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TMSB4X gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TMSB4X | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMSB4X | | Browse OriGene genome-wide validated SYBR primer pairs | | | OriGene Protein Over-expression Lysate for TMSB4X | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TMSB4X | | OriGene 3'-UTR Clone for TMSB4X | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMSB4X | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMSB4X | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TMSB4X | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TMSB4X | | OriGene Custom Protein Services for TMSB4X | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TMSB4X | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMSB4X | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMSB4X | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMSB4X | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMSB4X | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMSB4X |
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| | | | Search Tocris compounds for TMSB4X |
| |  |  |  |  | | | | | | Recombinant Protein for TMSB4X |
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 | | | | |  |  |  | | | | Search ThermoFisher Antibodies for TMSB4X |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMSB4X |
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