Aliases for TMSB4X Gene
External Ids for TMSB4X Gene
Previous HGNC Symbols for TMSB4X Gene
Previous GeneCards Identifiers for TMSB4X Gene
This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y. [provided by RefSeq, Jul 2008]
GeneCards Summary for TMSB4X Gene
TMSB4X (Thymosin Beta 4, X-Linked) is a Protein Coding gene. Diseases associated with TMSB4X include invasive malignant thymoma and colorectal cancer. Among its related pathways are Platelet activation, signaling and aggregation and Regulation of actin cytoskeleton. GO annotations related to this gene include poly(A) RNA binding and actin monomer binding. An important paralog of this gene is TMSB4Y.
UniProtKB/Swiss-Prot for TMSB4X Gene
Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase.