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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TMSB10 Gene

protein-coding GIFtS: 50
GCID: GC02P085132

thymosin beta 10

Explore 28 diseases affiliated with
TMSB10 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Thymosin Beta 10¹ ²		Migration-Inducing Protein 12²
TB10¹ ²		Thymosin Beta-10²
MIG12²		PTMB10³
Migration-Inducing Gene 12²		THYB10³

External Ids:	HGNC: 11879¹	Entrez Gene: 9168²	Ensembl: ENSG00000034510⁷	OMIM: 188399⁵	UniProtKB: P63313³

Export aliases for TMSB10 gene to outside databases

Previous GC identifers: GC02P085114 GC02P085426 GC02P085090 GC02P085107 GC02P085044 GC02P084986

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: TYB10_HUMAN, P63313

Function: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G

actin) and therefore inhibits actin polymerization (By similarity)

Gene Wiki entry for TMSB10

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_022184.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TMSB10 gene promoter:
p53 AP-1 p300 FOXO4 ATF-2 c-Jun
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TMSB10 promoter sequence

Search SABiosciences Chromatin IP Primers for TMSB10

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMSB10

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p11.2 Ensembl cytogenetic band: 2p11.2 HGNC cytogenetic band: 2p11.2

TMSB10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMSB10 gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P085132: view genomic region (about GC identifiers)

Start:	85,132,749 bp from pter	End:	85,133,799 bp from pter
Size:	1,051 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TYB10_HUMAN, P63313 (See protein sequence)

Recommended Name: Thymosin beta-10

Size: 44 amino acids; 5026 Da

Subcellular location: Cytoplasm, cytoskeleton

Developmental stage: Found to decrease dramatically after birth

Sequence caution: Sequence=AAA36746.1; Type=Erroneous initiation; Sequence=AAC41691.1; Type=Erroneous initiation;

Secondary accessions: P13472 Q596K9

Explore the universe of human proteins at neXtProt for TMSB10: NX_P63313

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P63313

TMSB10 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_066926.1

ENSEMBL proteins:

ENSP00000233143

Human Recombinant Protein Products:

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	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Uscn

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005856	cytoskeleton	IEA	--

TMSB10 for ontologies About GeneDecksing

TMSB10 Antibody Products:

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Assay Products for TMSB10:

	Browse Kits and Assays available from EMD Millipore
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	GenScript Custom Assay Services for TMSB10
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TMSB10 for domains About GeneDecksing

2 InterPro domains/families:

IPR001152 Thymosin_b4

IPR016323 Thymosin_b4_chordata

Graphical View of Domain Structure for InterPro Entry P63313

ProtoNet protein and cluster: P63313

1 Blocks protein family: IPB001152 Thymosin beta-4

UniProtKB/Swiss-Prot: TYB10_HUMAN, P63313

Similarity: Belongs to the thymosin beta family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: TYB10_HUMAN, P63313

Function: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G

actin) and therefore inhibits actin polymerization (By similarity)

miRNA Products:		OriGene 3'-UTR Clone: TMSB10 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMSB10
		8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate TMSB10 (see all 9):
		hsa-miR-148b hsa-miR-27a hsa-miR-657 hsa-miR-128 hsa-miR-3681* hsa-miR-1301 hsa-miR-152 hsa-miR-27b

		SwitchGear 3'UTR luciferase reporter plasmid: TMSB10 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMSB10 (see all 7) OriGene shRNA RFP: TMSB10 OriGene siRNA: TMSB10
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Gene Editing
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DNA2.0 Custom Protein Engineering Service for TMSB10

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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMSB10 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMSB10 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: TMSB10 (NM_021103)
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMSB10

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for TMSB10
		Search LifeMap BioReagents cell lines for TMSB10

In Situ Assay
Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for TMSB10

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003779	actin binding	IEA	--

TMSB10 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TMSB10

STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

5/8 Interacting proteins for TMSB10 (P63313³ ENSP00000233143⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 8)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TMOD1	P28289³, ENSP00000259365⁴	I2D: score=1 STRING: ENSP00000259365
FOS	P01100³, ENSP00000306245⁴	I2D: score=1 STRING: ENSP00000306245
SUFU	ENSP00000358918⁴	STRING: ENSP00000358918
UBC	ENSP00000344818⁴	STRING: ENSP00000344818
POT1	ENSP00000350249⁴	STRING: ENSP00000350249

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0030036	actin cytoskeleton organization	IEA	--
GO:0042989	sequestering of actin monomers	IEA	--

TMSB10 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

TMSB10 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TMSB10
2 Novoseek chemical compound relationships for TMSB10 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
retinoic acid	28.8	2	2169566 (2)
vegf	23.9	9	11156961 (3), 16496302 (2), 12914774 (1), 18854659 (1)

Search CenterWatch for drugs/clinical trials and news about TMSB10 / TYB10

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TMSB10 gene:

NM_021103.3

Unigene Cluster for TMSB10:

Thymosin beta 10

Hs.446574 [show with all ESTs]

Unigene Representative Sequence: BQ276852

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000233143(uc002sow.1)

miRNA Products:		OriGene 3'-UTR Clone: TMSB10 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMSB10
		8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate TMSB10 (see all 9):
		hsa-miR-148b hsa-miR-27a hsa-miR-657 hsa-miR-128 hsa-miR-3681* hsa-miR-1301 hsa-miR-152 hsa-miR-27b

		SwitchGear 3'UTR luciferase reporter plasmid: TMSB10 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMSB10 (see all 7) OriGene shRNA RFP: TMSB10 OriGene siRNA: TMSB10
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMSB10

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMSB10

Additional cDNA sequence:

AK130949.1 AK311952.1 AY453400.1 BC016025.1 BC016731.1 BC107889.1 M20259.1 M92381.1

S54005.1

24/41 DOTS entries (see all 41):

DT.455409 DT.99926681 DT.99926733 DT.121001526 DT.100701944 DT.95219544 DT.101985573 DT.121001374

DT.95222543 DT.100701960 DT.99994789 DT.100848983 DT.100757256 DT.97760238 DT.101985574 DT.121001398

DT.92466041 DT.92466043 DT.100701909 DT.100701911 DT.121001388 DT.121001422 DT.95221885 DT.100701924

24/1350 AceView cDNA sequences (see all 1350):

AA365522 AA307549 AA421628 BU626196 BU521099 BM757319 AU103119 F25762

AU103131 BQ231135 AJ705327 BQ674882 F36325 BM888592 BF724548 BQ712482

CB131510 BM796835 BQ230686 BM760559 BQ668952 BU181768 CB110572 AU103133

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for TMSB10 About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3a	·	3b	·	3c	·	3d
SP1:									-
SP2:
SP3:									-

ECgene alternative splicing isoforms for TMSB10

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TMSB10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGGAAATCG

About this image

TMSB10 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Limb

Zeugopod

Prechondrocytic Mesenchymal Cells

Bone, Cartilage

Ovary

Primary Follicle

Primary Oocyte

Female Gametocytes, Germ Cells

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

Endoderm-like cells (Generation of hepato...)

Definitive endoderm-like cells (A scalable, suspensi...)

See TMSB10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TMSB10

SOURCE GeneReport for Unigene cluster: Hs.446574

SABiosciences Expression via Pathway-Focused PCR Array including TMSB10:

Nephrotoxicity in human mouse rat

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		SABiosciences RT² qPCR Primer Assay in human, mouse / rat TMSB10
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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for TMSB10 gene from 1/6 species (see all 6) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
zebrafish (Danio rerio)	Actinopterygii	tmsb⁶ si:ch211-11c15.3⁶	si:ch211-11c15.3	73(a) 69(a)	1 ↔ many 1 ↔ many	21(25782878-25786220) 14(35617038-35619396)

ENSEMBL Gene Tree for TMSB10 (if available)
TreeFam Gene Tree for TMSB10 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TMSB10 gene

TMSB15B² TMSB15A² TMSB4Y² TMSB4XP4² TMSB4X²

5 SIMAP similar genes for TMSB10 using alignment to 2 protein entries: TYB10_HUMAN (see all proteins):

TMSB15A TMSB15B TMSB4X TMSB4XP4 TMSB4Y

TMSB10 for paralogs About GeneDecksing

3 Pseudogenes.org Pseudogenes for TMSB10
PGOHUM00000240566 PGOHUM00000235972 PGOHUM00000241657

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs146395141^1,2		--	85130764(+)	`ATAAGC/TGTGAT`	1	--	us2k¹		0	--	--	--	--
rs190065998^1,2		--	85130917(+)	`ACCCCA/GTCTCT`	1	--	us2k¹		0	--	--	--	--
rs10180066^1,2	C	--	85130921(+)	`cgtctC/Ttacta`	1	--	us2k¹		0	--	--	--	--
rs6711942^1,2	C,F,	--	85130945(+)	`tagccG/Agacat`	1	--	us2k¹		1		NA	4
rs6712044^1,2	C,	--	85131013(+)	`aacccA/Gggagg`	1	--	us2k¹		0	--	--	--	--
rs12477539^1,2	H	--	85131095(+)	`aaagaA/Gaaaaa`	1	--	us2k¹ trp³		0	--	--	--	--
rs6715126^1,2	C,F,A,H	--	85131170(+)	`AAAAAG/AAAAGA`	1	--	us2k¹ trp³		9		NS EA NA WA CSA	719
rs144342983^1,2		--	85131170(+)	`AAAAA-/GAAAGA`	1	--	us2k¹		0	--	--	--	--
rs144357200^1,2		--	85131197(+)	`TGCCTC/TTTCTT`	1	--	us2k¹		0	--	--	--	--
rs148738174^1,2		--	85131280(+)	`ACAAGC/GCTATG`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TMSB10 (85132749 - 85133799 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TMSB10: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMSB10

DNA2.0 Custom Variant and Variant Library Synthesis for TMSB10

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TMSB10 for disorders           About GeneDecksing

OMIM gene information: 188399    OMIM disorders: --

20/28 diseases for TMSB10 (see all 28):    About MalaCards

middle ear cholesteatoma graft versus host disease anaplastic large cell lymphoma rheumatic chorea

cholesteatoma interstitial lung disease goiter thyroid carcinoma

ovarian cancer scleroderma breast cancer pancreatitis

thyroiditis carcinoma choroiditis pancreatic cancer

prostate carcinoma melanoma lung cancer prostatitis

1 disease from the University of Copenhagen DISEASES database for TMSB10:

Tuberculosis

10/11 Novoseek disease relationships for TMSB10 gene (see all 11) About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
thyroid carcinoma	48.1	2	15254683 (1), 10487837 (1)
neoplastic transformation	33.7	1	9485041 (1)
pancreatic carcinoma	31	6	15983444 (1)
goiter	26.9	3	10366416 (2)
melanoma	15.7	4	8425765 (3)
tumors	15	13	14989934 (2), 14975205 (2), 11956663 (1), 15983444 (1) (see all 7)
cancer lung	15	4	18789485 (3)
cancer	14.9	8	11709704 (1), 19909017 (1), 11710837 (1), 16786322 (1) (see all 7)
breast cancer	13.3	3	16786322 (2), 8912542 (1)
ovarian cancer	4.89	6	11709704 (2)

Export disorders for TMSB10 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TMSB10 gene, integrated from 9 sources (see all 78):
(articles sorted by number of sources associating them with TMSB10)

Utopia: connect your pdf to the dynamic
world of online information

Sequence of a human kidney cDNA clone encoding thymosin beta 10. (PubMed id 3365256)^{1, 2, 3} McCreary V.... Toback F.G. (1988)
Thymosin beta 10 levels in developing human brain and its regulation by retinoic acid in the HTB-10 neuroblastoma. (PubMed id 2169566)^{1, 2, 9} Hall A.K.... Morgan J.I. (1990)
Thymosin beta-10 expression in melanoma cell lines and melanocytic lesions: a new progression marker for human cutaneous melanoma. (PubMed id 8425765)^{1, 2, 9} Weterman M.A.... Bloemers H.P.J. (1993)
Thymosin beta-10 gene overexpression is a general event in human carcinogenesis. (PubMed id 10487837)^{1, 3, 9} Santelli G....Fusco A. (1999)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Localization of thymosin beta10 in breast cancer cells: relationship to actin cytoskeletal remodeling and cell motility. (PubMed id 16786322)^{1, 9} Maelan A.E....Larsson L.I. (2007)
Expression of thymosin beta10 and its role in non-small cell lung cancer. (PubMed id 18789485)^{1, 9} Gu Y....Wang E. (2009)
The interaction between E-tropomodulin and thymosin beta-10 rescues tumor cells from thymosin beta-10 mediated apoptosis by restoring actin architecture. (PubMed id 14741341)^{1, 9} Rho S.B....Lee J.H. (2004)
Thymosin beta-10 is aberrantly expressed in pancreatic cancer and induces JNK activation. (PubMed id 19194824)^{1, 9} Li M....Yao Q. (2009)
The identification of apoptosis-related residues in human thymosin beta-10 by mutational analysis and computational modeling. (PubMed id 16012174)^{1, 9} Rho S.B....Lee J.H. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 9168	HGNC: 11879	AceView: TMSB10	Ensembl:ENSG00000034510	euGenes: HUgn9168
ECgene: TMSB10	H-InvDB: TMSB10

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TMSB10	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for TMSB10	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for TMSB10 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for TMSB10 gene:
Search GeneIP for patents involving TMSB10

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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TMSB10 Gene

thymosin beta 10

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TMSB10 Gene

thymosin beta 10

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for TMSB10 gene

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for TMSB10 gene

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for TMSB10 gene

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Expression
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Intellectual Property
for TMSB10 gene

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