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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMPRSS5 Gene

protein-coding   GIFtS: 49
GCID: GC11M113592

Transmembrane Protease, Serine 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transmembrane Protease, Serine 51 2     EC 3.4.21.-3
spinesin1     Spinesin3
SPINESIN2     EC 3.4.218
Transmembrane Protease Serine 52     EC 3.4.21.48

External Ids:    HGNC: 149081   Entrez Gene: 809752   Ensembl: ENSG000001666827   OMIM: 6067515   UniProtKB: Q9H3S33   

Export aliases for TMPRSS5 gene to outside databases

Previous GC identifers: GC11M115911 GC11M115070 GC11M113095 GC11M113063 GC11M109486


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TMPRSS5 Gene:
This gene encodes a protein that belongs to the serine protease family. Serine proteases are known to be involved
in many physiological and pathological processes. (provided by RefSeq, Jul 2008)

GeneCards Summary for TMPRSS5 Gene: 
TMPRSS5 (transmembrane protease, serine 5) is a protein-coding gene. Diseases associated with TMPRSS5 include gout, and neuronitis. GO annotations related to this gene include scavenger receptor activity and serine-type endopeptidase activity. An important paralog of this gene is TMPRSS11D.

UniProtKB/Swiss-Prot: TMPS5_HUMAN, Q9H3S3
Function: May play a role in hearing




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_033899.8  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMPRSS5 gene promoter:
         STAT5B   STAT1   STAT4   STAT1beta   Pax-2   STAT5A   Pax-2a   STAT1alpha   STAT2   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMPRSS5 promoter sequence
   Search SABiosciences Chromatin IP Primers for TMPRSS5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMPRSS5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q   Ensembl cytogenetic band:  11q23.2   HGNC cytogenetic band: 11q

TMPRSS5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMPRSS5 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M113592:  view genomic region     (about GC identifiers)

Start:
113,558,268 bp from pter      End:
113,577,095 bp from pter
Size:
18,828 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TMPS5_HUMAN, Q9H3S3 (See protein sequence)
Recommended Name: Transmembrane protease serine 5  
Size: 457 amino acids; 49560 Da
Subcellular location: Cell membrane; Single-pass type II membrane protein (Potential)

Explore the universe of human proteins at neXtProt for TMPRSS5: NX_Q9H3S3

Explore proteomics data for TMPRSS5 at MOPED 

4/7 DME Specific Peptides for TMPRSS5 (Q9H3S3) (see all 7)
 GDSGGPL  SGGPLVC  LVGVVSWG  CQGDSGGP 

TMPRSS5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

TMPRSS5 Protein Expression
REFSEQ proteins: NP_110397.2  
ENSEMBL proteins: 
 ENSP00000437937   ENSP00000437761   ENSP00000299882   ENSP00000441104   ENSP00000445528  
 ENSP00000440783   ENSP00000445930   ENSP00000443681   ENSP00000445502   ENSP00000440976  

Human Recombinant Protein Products for TMPRSS5: 
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Novus Biologicals TMPRSS5 Lysates
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for TMPRSS5 

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005886plasma membrane IDA17918732
GO:0016020membrane ----
GO:0016021integral to membrane IEA--
GO:0043025neuronal cell body IEA--

TMPRSS5 for ontologies           About GeneDecksing



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Cloud-Clone Corp. CLIAs for TMPRSS5


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
TMPRSS: Serine peptidases / Transmembrane

5/6 InterPro protein domains (see all 6):
 IPR001314 Peptidase_S1A
 IPR001190 Srcr_rcpt
 IPR009003 Trypsin-like_Pept_dom
 IPR017448 Srcr_rcpt-rel
 IPR001254 Peptidase_S1

Graphical View of Domain Structure for InterPro Entry Q9H3S3

ProtoNet protein and cluster: Q9H3S3

2 Blocks protein domains:
IPB001254 Serine protease
IPB001314 Chymotrypsin serine protease family (S1) signature


UniProtKB/Swiss-Prot: TMPS5_HUMAN, Q9H3S3
Similarity: Belongs to the peptidase S1 family
Similarity: Contains 1 peptidase S1 domain
Similarity: Contains 1 SRCR domain


TMPRSS5 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: TMPS5_HUMAN, Q9H3S3
Function: May play a role in hearing

     Enzyme Numbers (IUBMB): EC 3.4.21.42 EC 3.4.212 EC 3.4.21.-1

     Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003824catalytic activity ----
GO:0004252serine-type endopeptidase activity IEA--
GO:0005044scavenger receptor activity IEA--
GO:0008233peptidase activity IMP17918732
     
TMPRSS5 for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for TMPRSS5 
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMPRSS5 
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miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMPRSS5
3 QIAGEN miScript miRNA Assays for microRNAs that regulate TMPRSS5:
hsa-miR-877* hsa-miR-766 hsa-miR-3918
SwitchGear 3'UTR luciferase reporter plasmidTMPRSS5 3' UTR sequence
Inhib. RNA
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Gene Editing
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Clone
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OriGene clones in human, mouse for TMPRSS5 (see all 7)
OriGene ORF clones in mouse, rat for TMPRSS5
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GenScript: all cDNA clones in your preferred vector: TMPRSS5 (NM_030770)
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Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMPRSS5


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMPRSS5

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006508proteolysis IMP17918732

TMPRSS5 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TMPRSS5 (TMPS5)

Search CenterWatch for drugs/clinical trials and news about TMPRSS5 / TMPS5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TMPRSS5 gene: 
NM_030770.2  

Unigene Cluster for TMPRSS5:

Transmembrane protease, serine 5
Hs.46720  [show with all ESTs]
Unigene Representative Sequence: AF495727
12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000536856 ENST00000540540 ENST00000299882(uc001poc.4 uc009yys.3 uc009yyt.3 uc001pod.4 uc010rww.2 uc009yyu.3 uc010rwx.2)
ENST00000545579 ENST00000538955 ENST00000544634 ENST00000544476 ENST00000545265
ENST00000545412 ENST00000539732 ENST00000538770 ENST00000538091
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMPRSS5
3 QIAGEN miScript miRNA Assays for microRNAs that regulate TMPRSS5:
hsa-miR-877* hsa-miR-766 hsa-miR-3918
SwitchGear 3'UTR luciferase reporter plasmidTMPRSS5 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for TMPRSS5
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMPRSS5
Clone
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OriGene ORF clones in mouse, rat for TMPRSS5
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GenScript: all cDNA clones in your preferred vector: TMPRSS5 (NM_030770)
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMPRSS5
Sirion Biotech Customized lentivirus for stable overexpression of TMPRSS5 
                     Customized lentivirus expression plasmids for stable overexpression of TMPRSS5 
Primer
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OriGene qSTAR qPCR primer pairs in human, mouse for TMPRSS5
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  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMPRSS5
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMPRSS5

Additional mRNA sequence: 

AB028140.1 AF495727.1 AK294313.1 AK295366.1 BC028065.1 BC047222.1 BC121802.1 BC121803.1 

5 DOTS entries:

DT.101978242  DT.101978241  DT.107841  DT.100677419  DT.120706743 

24/35 AceView cDNA sequences (see all 35):

AI597622 AL538140 CD516647 BC028065 BF515139 BI757597 AI967938 BM977058 
BF934870 AI085672 AI056603 AI197773 NM_030770 CB115630 AI825589 AI201055 
BQ575647 BI601373 AI052212 AI631456 CK004430 AI653241 AB028140 BC047222 

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for TMPRSS5 (see all 7)    About this scheme

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16
SP1:                    -                 -                 -                 -     -                 -                           
SP2:              -     -     -           -                 -                 -     -                                             
SP3:              -     -     -     -     -                 -                 -     -                                             
SP4:              -     -     -     -     -                                                                                       
SP5:                                                                                                  -                           


ECgene alternative splicing isoforms for TMPRSS5

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TMPRSS5 expression in normal human tissues (normalized intensities)      TMPRSS5 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GCTGAGAGGC
TMPRSS5 Expression
About this image


TMPRSS5 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/2 selected tissues (see all 2) fully expand
 
 Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
         Muscle Progenitor Cells Mandibular Arch Muscles
 
 Brain (Nervous System)
         Myelinating Oligodendrocyte Cells Forebrain White Matter

See TMPRSS5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TMPRSS5

SOURCE GeneReport for Unigene cluster: Hs.46720

UniProtKB/Swiss-Prot: TMPS5_HUMAN, Q9H3S3
Tissue specificity: Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of
motoneurons in the spinal cord

    SABiosciences Custom PCR Arrays for TMPRSS5
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMPRSS5

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for TMPRSS5 gene from 6/14 species (see all 14)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Tmprss51 , 5 transmembrane protease, serine 5 (spinesin)1, 5 80.66(n)1
79.23(a)1
  9 (26.59 cM)5
808931  NM_030709.21  NP_109634.21 
 490812605 
chicken
(Gallus gallus)
Aves LOC1008592341 transmembrane protease serine 5-like 64.29(n)
57.74(a)
  100859234  XM_003642614.1  XP_003642662.1 
lizard
(Anolis carolinensis)
Reptilia TMPRSS56
transmembrane protease, serine 5
45(a)
1 ↔ 1
GL343354.1(307252-318507)
zebrafish
(Danio rerio)
Actinopterygii TMPRSS56
zgc:558886
zgc:55888
49(a)
16(a)
1 ↔ 1
possible ortholog
15(17108080-17116968)
4(8538926-8547751)
mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP0047701 AGAP004770-PA 50.45(n)
47.75(a)
  1278456  XM_318046.3  XP_318046.3 
worm
(Caenorhabditis elegans)
Secernentea try-16
Protein TRY-1
33(a)
1 → many
II(4948154-4949486)


ENSEMBL Gene Tree for TMPRSS5 (if available)
TreeFam Gene Tree for TMPRSS5 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for TMPRSS5 gene
TMPRSS11D2  TMPRSS32  TMPRSS11B2  TMPRSS62  TMPRSS11A2  TMPRSS72  TMPRSS42  ST142  
TMPRSS132  TMPRSS11E2  KLKB12  TMPRSS22  F112  HPN2  TMPRSS152  TMPRSS11F2  
18/99 SIMAP similar genes for TMPRSS5 using alignment to 12 protein entries:     TMPS5_HUMAN (see all proteins) (see all similar genes):
MGC52282    serase-1B    F12    CTRB2    DKFZp586F0824    CTRB1
KLKB1    F11    TMPRSS3    ST14    DKFZp779M0222    PRSS22
TMPRSS11D    TMPRSS11B    DESC1    TMPRSS11E    TMPRSS11F    ACR

TMPRSS5 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/487 SNPs in TMPRSS5 are shown (see all 487)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0380054
----see VAR_0380052 D V mis40--------
VAR_0380094
----see VAR_0380092 A S mis40--------
VAR_0380104
----see VAR_0380102 P S mis40--------
VAR_0380084
----see VAR_0380082 A V mis40--------
rs1846003911,2
C--113557876(+) ATTACA/CGGGGT 1 -- ds50010--------
rs65893911,2
C,A--113557891(+) caccgC/Tgccca 1 -- ds50013Minor allele frequency- T:0.14NS WA 36
rs1493047891,2
--113557925(+) TTAAAG/TAATTA 1 -- ds50010--------
rs1903817781,2
--113558046(+) AACATC/TGAGGC 1 -- ds50010--------
rs1506562131,2
C--113558209(+) GTTTG-/TGTC  
        
TGTCT
1 -- ds50010--------
rs1120147561,2
C--113558226(+) CTGTCC/TGTCTG 1 -- ds50011Minor allele frequency- T:0.50CSA 2

HapMap Linkage Disequilibrium report for TMPRSS5 (113558268 - 113577095 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for TMPRSS5: --

Human Gene Mutation Database (HGMD): TMPRSS5
SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing TMPRSS5
DNA2.0 Custom Variant and Variant Library Synthesis for TMPRSS5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 606751    OMIM disorders: --

UniProtKB/Swiss-Prot: TMPS5_HUMAN, Q9H3S3
  • Note=Defects in TMPRSS5 may be a cause of deafness

  • 2 diseases for TMPRSS5:    About MalaCards
    gout    neuronitis


    TMPRSS5 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TMPRSS5

    Export disorders for TMPRSS5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TMPRSS5 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TMPRSS5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Spinesin/TMPRSS5, a novel transmembrane serine protease, cloned from human spinal cord. (PubMed id 11741986)1, 2, 9 Yamaguchi N.... Mitsui S. (2002)
    2. An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss. (PubMed id 17918732)1, 2 Guipponi M.... Scott H.S. (2008)
    3. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    5. ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts. (PubMed id 12484779)1 Mohan S....Baylink D.J. (2002)
    6. Molecular cloning and tissue-specific expression analysis of mouse spinesin, a type II transmembrane serine protease 5. (PubMed id 15465023)9 Watanabe Y....Yamaguchi N. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80975 HGNC: 14908 AceView: TMPRSS5 Ensembl:ENSG00000166682 euGenes: HUgn80975
    ECgene: TMPRSS5 H-InvDB: TMPRSS5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMPRSS5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TMPRSS5 gene:
    Search GeneIP for patents involving TMPRSS5

    GeneCards and IP:
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