Aliases for TMPRSS4 Gene
External Ids for TMPRSS4 Gene
Previous GeneCards Identifiers for TMPRSS4 Gene
This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for TMPRSS4 Gene
TMPRSS4 (Transmembrane Protease, Serine 4) is a Protein Coding gene. Diseases associated with TMPRSS4 include autosomal recessive cerebral atrophy. Among its related pathways are Influenza A. GO annotations related to this gene include serine-type endopeptidase activity and scavenger receptor activity. An important paralog of this gene is TMPRSS11A.
UniProtKB/Swiss-Prot for TMPRSS4 Gene
Probable protease. Seems to be capable of activating ENaC (By similarity).