Aliases for TMPRSS3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb, and/or 11Nature:405,311-319 and CroW21) About This Section
| This gene clusters with an RNA gene Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Transmembrane Protease, Serine 31 2 | | TADG122 3 | | DFNB101 2 5 | | Gene Similar To Transmembrane Serine Protease11 | | DFNB81 2 5 | | Transmembrane Protease Serine 32 | | ECHOS12 3 5 | | EC 3.4.21.-3 | | Serine Protease TADG-122 3 | | EC 3.4.218 | | Tumor-Associated Differentially-Expressed Gene 12 Protein2 3 | | |
| External Ids: | HGNC: 118771 | Entrez Gene: 646992 | Ensembl: ENSG000001601837 | OMIM: 6055115 | UniProtKB: P577273 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n407814 | |
Export aliases for TMPRSS3 gene to outside databasesPrevious GC identifers: GC21M040339 GC21M042686 GC21M042665 GC21M029209 GC21M038437
Summaries for TMPRSS3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for TMPRSS3: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine proteasedomain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serineproteases are known to be involved in a variety of biological processes, whose malfunction often leads to humandiseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomalrecessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved inthe development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was alsoidentified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcriptvariants have been described. (provided by RefSeq, Jan 2012) UniProtKB/Swiss-Prot: TMPS3_HUMAN, P57727Function: Probable serine protease that play a role in hearing. Acts as a permissive factor for cochlear hair cellssurvival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity).Activates ENaC (in vitro) Gene Wiki entry for TMPRSS3
|
Genomic Views for TMPRSS3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics, Whole Chromsome Sequence According to
Nature (Cited Here with Permission):405,311-319 and CroW21) About This Section
|
| GC21M043791: |
GeneLoc |
Nature:405,311-319 |
Start:
|
43,791,996 bp from pter |
29,339,326 bp from centromere |
End:
|
43,816,955 bp from pter |
29,363,526 bp from centromere |
Size:
|
24,960 bases |
24,201 bases |
Orientation:
|
minus strand |
minus strand |
Proteins for TMPRSS3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: TMPS3_HUMAN, P57727 (See
protein sequence)Recommended Name: Transmembrane protease serine 3 Size: 454 amino acids; 49405 Da
Subcellular location: Endoplasmic reticulum membrane; Single-pass type II membrane protein
Secondary accessions: D3DSJ6 Q6ZMC3Alternative splicing: 5 isoforms: P57727-1 P57727-2 P57727-3 P57727-4 P57727-5 Explore the universe of human proteins at neXtProt for TMPRSS3: NX_P57727
Post-translational modifications:
Undergoes autoproteolytic activation1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P57727 4 DME Specific Peptides for TMPRSS3 (P57727)
TMPRSS3 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins (4 alternative transcripts):
NP_001243246.1 NP_076927.1 NP_115780.1 NP_115781.1 ENSEMBL proteins: ENSP00000381442 ENSP00000411013 ENSP00000291532 ENSP00000381434 ENSP00000369762 Human Recombinant Protein Products for TMPRSS3:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
TMPRSS3 for ontologies About GeneDecksing
TMPRSS3 Antibody Products: Assay Products for TMPRSS3: |
Protein
Domains / Families for TMPRSS3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TMPRSS3 for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry P57727ProtoNet protein and cluster: P57727 4 Blocks protein families: IPB001190 Speract/scavenger receptor IPB001254 Serine protease IPB001314 Chymotrypsin serine protease family (S1) signature IPB002172 Low density lipoprotein-receptor
UniProtKB/Swiss-Prot: TMPS3_HUMAN, P57727Similarity: Belongs to the peptidase S1 familySimilarity: Contains 1 LDL-receptor class A domainSimilarity: Contains 1 peptidase S1 domainSimilarity: Contains 1 SRCR domain |
Function for TMPRSS3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: TMPS3_HUMAN, P57727Function: Probable serine protease that play a role in hearing. Acts as a permissive factor for cochlear hair cellssurvival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity).Activates ENaC (in vitro) Enzyme Numbers (IUBMB): EC 3.4.212 EC 3.4.21.-1
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
TMPRSS3 for ontologies About GeneDecksing
Phenotypes: 1 GenomeRNAi human phenotype for TMPRSS3: 3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Tmprss3):
TMPRSS3 for phenotypes About GeneDecksing
Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMPRSS3 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMPRSS3 (see all 4) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TMPRSS3 (NM_032405) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMPRSS3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMPRSS3  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMPRSS3 |
|
Pathways & Interactions for TMPRSS3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMPRSS3
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
 5/8 Interacting proteins for TMPRSS3 (P577272, 3 ENSP000002915324) via UniProtKB, MINT, STRING, and/or I2D (see all 8)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
TMPRSS3 for ontologies About GeneDecksing
|
Drugs & Compounds for TMPRSS3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
TMPRSS3 for compounds About GeneDecksing
Browse Tocris compounds for TMPRSS3 1 Novoseek chemical compound relationship for TMPRSS3 gene About this table
Search CenterWatch for drugs/clinical trials and news about TMPRSS3 / TMPS3 
|
Transcripts for TMPRSS3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for TMPRSS3 gene (5 alternative transcripts): NM_001256317.1 NM_024022.2 NM_032404.2 NM_032405.1 NM_032401.1 Unigene Cluster for TMPRSS3: Transmembrane protease, serine 3 Hs.208600 [show with all ESTs]Unigene Representative Sequence: NR_0460209 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000476848(uc002zay.2) ENST00000474596(uc002zaz.2) ENST00000482761(uc002zba.2) ENST00000398405 ENST00000433957 ENST00000291532(uc002zbb.2 uc002zbc.2) ENST00000398397(uc002zbd.3) ENST00000478680 ENST00000380399
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMPRSS3 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMPRSS3 (see all 4) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TMPRSS3 (NM_032405) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMPRSS3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMPRSS3  |
Additional cDNA sequence: AB038157.1 AB038158.1 AB038159.1 AB038160.1 AF201380.1 AF267741.1 AK172842.1 AY358458.1 AY633572.1 BC074846.2 BC074847.2 NR_046020.1 7 DOTS entries: DT.92418060 DT.75100241 DT.95314059 DT.100019257 DT.100771966 DT.99936886 DT.75147373 24/190 AceView cDNA sequences (see all 190): BM768238 AB038160 NM_032404 NM_032405 NM_024022 BM767158 BM855291 BM856224 BM853943 BM768507 AI970839 BX341674 BM142503 AI925552 BM856488 BM817954 BM853888 BM855692 BM798931 AA524242 CK820254 AA858276 BM854657 BM855263 GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for TMPRSS3 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | |
| SP1: | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for TMPRSS3
|
Expression for TMPRSS3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TMPRSS3 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TTGGTGTTGG
 About this image See TMPRSS3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for TMPRSS3
SOURCE GeneReport for Unigene cluster: Hs.208600
UniProtKB/Swiss-Prot: TMPS3_HUMAN, P57727Tissue specificity: Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in somecarcinomas SABiosciences Custom PCR Arrays for TMPRSS3
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMPRSS3 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMPRSS3 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMPRSS3 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMPRSS3 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMPRSS3 |
Orthologs for TMPRSS3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TMPRSS3 gene from 4/12 species (see all 12) About this table
ENSEMBL Gene Tree for TMPRSS3 (if available) TreeFam Gene Tree for TMPRSS3 (if available)  |
Paralogs for TMPRSS3 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for TMPRSS3 gene
- TMPRSS72 TMPRSS52 ST142 TMPRSS42 TMPRSS11D2 TMPRSS132 TMPRSS11E2 TMPRSS11B2
- TMPRSS22 TMPRSS92 HPN2 TMPRSS152 TMPRSS11F2 TMPRSS11A2 TMPRSS62
18/88 SIMAP similar genes for TMPRSS3 using alignment to 3 protein entries: TMPS3_HUMAN (see all proteins)
(see all similar genes):KLKB1 F12 CTRL TMPRSS11F CTRB1 DKFZp779M0222 CTRB2 PRSS46 CELA2B TMPRSS5 PRSS8 TPSG1 CELA3A HPN PRSS21 TMPRSS2 serase-1B PROC1
TMPRSS3 for paralogs About GeneDecksing
|
Genomic Variants for TMPRSS3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 21 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for TMPRSS3 (43791996 - 43816955 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for TMPRSS3: -- Human Gene Mutation Database (HGMD): TMPRSS3
Locus Specific Mutation Databases (LSDB): TMPRSS3
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMPRSS3 |
|
Disorders
/ Diseases for TMPRSS3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TMPRSS3 for disorders About GeneDecksing
OMIM gene information: 605511 OMIM disorders: 601072 605316 UniProtKB/Swiss-Prot: TMPS3_HUMAN, P57727
Defects in TMPRSS3 are the cause of deafness autosomal recessive type 8 (DFNB8) [MIM:601072]. DFNA8 is a formof sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear,the nerve pathways to the brain, or the area of the brain that receives sound information Defects in TMPRSS3 are the cause of deafness autosomal recessive type 10 (DFNB10) [MIM:605316] 9 diseases for TMPRSS3: About MalaCardsdeafness, autosomal recessive 8, childhood onset deafness, autosomal recessive 10, congenital hearing loss nonsyndromic deafness ovarian cancer gout pancreatic cancer carcinoma pancreatitis 1 disease from the University of Copenhagen DISEASES database for TMPRSS3:Nonsyndromic deafness 5 Novoseek disease relationships for TMPRSS3 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| congenital deafness |
76.7 |
2 |
15447792 (2) |
| ovarian carcinoma |
46.7 |
4 |
11068177 (1), 15361711 (1) |
| ovarian cancer |
33 |
1 |
11068177 (1) |
| carcinoma |
10.7 |
1 |
11068177 (1) |
| tumors |
0 |
2 |
11068177 (2) |
Genetic Association Database (GAD): TMPRSS3 Human Genome Epidemiology (HuGE) Navigator: TMPRSS3 (1 document) Export disorders for TMPRSS3 gene to outside databases
|
Publications for TMPRSS3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TMPRSS3 gene, integrated from 9 sources (see all 35): (articles sorted by number of sources associating them with TMPRSS3) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Mutations in the TMPRSS3 gene are a rare cause of childhood nonsyndromic deafness in Caucasian patients. (PubMed id 11907649)1, 2, 3, 4, 9 Wattenhofer M....Antonarakis S.E. (2002)
- Novel missense mutations of TMPRSS3 in two consanguineous Tunisian families with non-syndromic autosomal recessive deafness. (PubMed id 11462234)1, 2, 3, 9 Masmoudi S.... Guipponi M. (2001)
- The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro. (PubMed id 12393794)1, 2, 9 Guipponi M.... Rossier B.C. (2002)
- Ovarian tumor cells express a novel multi-domain cell surface serine protease. (PubMed id 11068177)1, 2, 9 Underwood L.J.... O'Brien T.J. (2000)
- Insertion of beta-satellite repeats identifies a transmembrane protease causing both congenital and childhood onset autosomal recessive deafness. (PubMed id 11137999)1, 2, 9 Scott H.S....Antonarakis S.E. (2001)
- A novel TMPRSS3 missense mutation in a DFNB8/10 family prevents proteolytic activation of the protein. (PubMed id 16021470)1, 2 Wattenhofer M.... Antonarakis S.E. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- Novel mutations of TMPRSS3 in four DFNB8/B10 families segregating congenital autosomal recessive deafness. (PubMed id 11424922)1, 2 Ben-Yosef T.... Morell R.J. (2001)
|
External Searches for TMPRSS3 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing TMPRSS3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TMPRSS3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TMPRSS3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for TMPRSS3 gene: Search GeneIP for patents involving TMPRSS3
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for TMPRSS3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
 |
| | | | OriGene Antibodies for TMPRSS3 | | OriGene shRNA RFP for TMPRSS3 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMPRSS3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMPRSS3 | | OriGene Protein Over-expression Lysate for TMPRSS3 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for TMPRSS3 | | OriGene 3'-UTR Clone for TMPRSS3 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMPRSS3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMPRSS3 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for TMPRSS3 | | OriGene Custom Protein Services for TMPRSS3 | | OriGene Custom Immunoassay Development | | |
| |  |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TMPRSS3 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMPRSS3 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMPRSS3 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMPRSS3 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMPRSS3 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMPRSS3 |
| |
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| | | Search Tocris compounds for TMPRSS3 |
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 | | TMPRSS3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMPRSS3 |
|  |  |  |  | | | ThermoFisher Antibodies for TMPRSS3 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMPRSS3 |
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