TMPRSS11BNL Gene
protein-coding GIFtS: 29
GCID: GC04M069055
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TMPRSS11B N terminal-like
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Aliases
for TMPRSS11BNL gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| TMPRSS11B N Terminal-Like1 2 | | TMPRSS11B N-Terminus-Like Protein2 3 | | FLJ415621 | | Transmembrane Protease Serine 11B-Like Protein2 |
Export aliases for TMPRSS11BNL gene to outside databasesPrevious GC identifer: GC04M064969 |
Summaries
for TMPRSS11BNL gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TMPRSS11BNL gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_022778.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for TMPRSS11BNL
Other transcription factors
Search SABiosciences Chromatin IP Primers for TMPRSS11BNL
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMPRSS11BNL |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q13.2 Ensembl cytogenetic band: 4q13.2 HGNC cytogenetic band: 4q13.2TMPRSS11BNL Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M069055: view genomic region
(about GC identifiers)
Start:
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69,054,242 bp from pter |
End:
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69,083,798 bp from pter |
Size:
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29,557 bases |
Orientation:
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minus strand |
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Proteins
for TMPRSS11BNL gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TM11L_HUMAN, B3KVV0 (See
protein sequence)Recommended Name: Transmembrane protease serine 11B-like protein Size: 105 amino acids; 12224 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Caution: Although similar to the N-terminus of TMPRSS11B, it is much shorter and lacks the C-terminal part thatcontains the peptidase S1 domain
Caution: Localized in the opposite strand of ferritin light chain-like pseudogeneExplore the universe of human proteins at neXtProt for TMPRSS11BNL: NX_B3KVV0
TMPRSS11BNL Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001123379.1
ENSEMBL proteins: ENSP00000391149
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
TMPRSS11BNL for ontologies About GeneDecksing
TMPRSS11BNL Antibody Products:
Assay Products for TMPRSS11BNL: |
Protein
Domains /
Families
for TMPRSS11BNL gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: B3KVV0 |
Function
for TMPRSS11BNL gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMPRSS11BNL (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMPRSS11BNL
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TMPRSS11BNL (NM_001129907) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMPRSS11BNL | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TMPRSS11BNL |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMPRSS11BNL |
|
Pathways & Interactions
for TMPRSS11BNL gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMPRSS11BNL
|
Drugs & Compounds
for TMPRSS11BNL gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TMPRSS11BNL
Search CenterWatch for drugs/clinical trials and news about TMPRSS11BNL / TM11L
|
Transcripts
for TMPRSS11BNL gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TMPRSS11BNL gene: NM_001129907.2 Unigene Cluster for TMPRSS11BNL: TMPRSS11B N terminal-like Hs.652046 [show with all ESTs]Unigene Representative Sequence: AK1235561 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000432593
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMPRSS11BNL (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMPRSS11BNL
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TMPRSS11BNL (NM_001129907) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMPRSS11BNL | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TMPRSS11BNL |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMPRSS11BNL
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat TMPRSS11BNL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMPRSS11BNL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMPRSS11BNL |
Additional cDNA sequence: AK123556.1 1 DOTS entry: DT.101969115 2 AceView cDNA sequences: AK123556 BX505030
GeneLoc Exon Structure
|
Expression
for TMPRSS11BNL gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TMPRSS11BNL expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CATACTGTCA
About this image
See TMPRSS11BNL Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.652046
SABiosciences Custom PCR Arrays for TMPRSS11BNL
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMPRSS11BNL
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat TMPRSS11BNL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMPRSS11BNL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMPRSS11BNL | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMPRSS11BNL |
Orthologs
for TMPRSS11BNL gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for TMPRSS11BNL gene from 1 species (see representative species ) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Tmprss11bnl5 |
transmembrane protease, serine 11b N terminal like |
-- |
|
5 (43.56 cM) 86657631 |
ENSEMBL Gene Tree for TMPRSS11BNL (if available)
TreeFam Gene Tree for TMPRSS11BNL (if available) |
Paralogs
for TMPRSS11BNL gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TMPRSS11BNL gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for TMPRSS11BNL
1 CNV: 36290 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMPRSS11BNL |
|
Disorders
/ Diseases
for TMPRSS11BNL gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for TMPRSS11BNL gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TMPRSS11BNL gene integrated from 9 sources:
(articles sorted by number of sources associating them with TMPRSS11BNL) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
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External Searches for TMPRSS11BNL gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing TMPRSS11BNL gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TMPRSS11BNL gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TMPRSS11BNL gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TMPRSS11BNL | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TMPRSS11BNL gene:
Search GeneIP for patents involving TMPRSS11BNL
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TMPRSS11BNL gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TMPRSS11BNL | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMPRSS11BNL | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMPRSS11BNL | | | OriGene Protein Over-expression Lysate for TMPRSS11BNL | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMPRSS11BNL | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMPRSS11BNL | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TMPRSS11BNL | | OriGene Custom Protein Services for TMPRSS11BNL | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TMPRSS11BNL | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMPRSS11BNL | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMPRSS11BNL | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMPRSS11BNL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMPRSS11BNL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMPRSS11BNL |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMPRSS11BNL |
|  |  |  | | | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TMPRSS11BNL |
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