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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TMPRSS11A Gene

protein-coding GIFtS: 48
GCID: GC04M068776

transmembrane protease, serine 11A

Explore 28 diseases affiliated with
TMPRSS11A via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Transmembrane Protease, Serine 11A¹ ²		Transmembrane Protease Serine 11A²
ECRG1¹ ² ³ ⁵		EC 3.4.21.-³
Airway Trypsin-Like Protease 1² ³		HATL1³
Epidermal Type-II Transmembrane Serine Protease² ³		HESP³
Esophageal Cancer-Susceptibility Gene 1 Protein² ³		EC 3.4.21⁸
Epidermal Type II Transmembrane Serine Protease²

External Ids:	HGNC: 27954¹	Entrez Gene: 339967²	Ensembl: ENSG00000187054⁷	OMIM: 611704⁵	UniProtKB: Q6ZMR5³

Export aliases for TMPRSS11A gene to outside databases

Previous GC identifers: GC04M068605 GC04M068459 GC04M064689

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: TM11A_HUMAN, Q6ZMR5

Function: Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth

and induce G1 cell cycle arrest

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000004.11 NC_018915.1 NT_022778.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TMPRSS11A gene promoter:
STAT5B Pbx1a FOXD1 FOXO3 FOXO3b FOXL1 HFH-1 FOXO3a Pax-4a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TMPRSS11A promoter sequence

Search SABiosciences Chromatin IP Primers for TMPRSS11A

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMPRSS11A

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q13.2 Ensembl cytogenetic band: 4q13.2 HGNC cytogenetic band: 4q13.2

TMPRSS11A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMPRSS11A gene location

GeneLoc information about chromosome 4 GeneLoc Exon Structure

GeneLoc location for GC04M068776: view genomic region (about GC identifiers)

Start:	68,775,103 bp from pter	End:	68,829,858 bp from pter
Size:	54,756 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TM11A_HUMAN, Q6ZMR5 (See protein sequence)

Recommended Name: Transmembrane protease serine 11A

Size: 421 amino acids; 47569 Da

Subunit: May interact with ZBTB17

Subcellular location: Membrane; Single-pass type II membrane protein (Potential)

Sequence caution: Sequence=AAD41463.1; Type=Frameshift; Positions=371; Sequence=CAD67985.1; Type=Erroneous gene model

prediction;

Secondary accessions: Q2NKI9 Q6JE90 Q7RTY4 Q86TK8

Alternative splicing: 2 isoforms: Q6ZMR5-1 Q6ZMR5-2

Explore the universe of human proteins at neXtProt for TMPRSS11A: NX_Q6ZMR5

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6ZMR5

3 DME Specific Peptides for TMPRSS11A (Q6ZMR5)

GDSGGPL

DIAVVQV

WIASKTG

TMPRSS11A Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001107859.1 NP_872412.3

ENSEMBL proteins:

ENSP00000426911 ENSP00000334611 ENSP00000427621 ENSP00000379491

Human Recombinant Protein Products for TMPRSS11A:

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	Uscn Proteins for TMPRSS11A

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005886	plasma membrane	--	--
GO:0005887	integral to plasma membrane	IEA	--

TMPRSS11A for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for TMPRSS11A

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TMPRSS11A for domains About GeneDecksing

5/6 InterPro domains/families (see all 6):

IPR001314 Peptidase_S1A

IPR000082 SEA

IPR017329 Pept_S1A_HAT/DESC1

IPR009003 Trypsin-like_Pept_dom

IPR001254 Peptidase_S1

Graphical View of Domain Structure for InterPro Entry Q6ZMR5

ProtoNet protein and cluster: Q6ZMR5

3 Blocks protein families:

IPB000082 SEA domain

IPB001254 Serine protease

IPB001314 Chymotrypsin serine protease family (S1) signature

UniProtKB/Swiss-Prot: TM11A_HUMAN, Q6ZMR5

Similarity: Belongs to the peptidase S1 family

Similarity: Contains 1 peptidase S1 domain

Similarity: Contains 1 SEA domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: TM11A_HUMAN, Q6ZMR5

Function: Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth

and induce G1 cell cycle arrest

Enzyme Numbers (IUBMB): EC 3.4.21² EC 3.4.21.-¹

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004252	serine-type endopeptidase activity	IEA	--

TMPRSS11A for ontologies About GeneDecksing

Phenotypes:
3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Tmprss11a):

endocrine/exocrine gland

normal

reproductive system

TMPRSS11A for phenotypes About GeneDecksing

Animal Models:
Mouse knock-out Tmprss11a^tm1Dgen for TMPRSS11A

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TMPRSS11A

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMPRSS11A
		1 QIAGEN miScript miRNA Assays for microRNA that regulate TMPRSS11A:
		hsa-miR-1305
		SwitchGear 3'UTR luciferase reporter plasmid: TMPRSS11A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMPRSS11A (see all 4) OriGene shRNA RFP: TMPRSS11A OriGene siRNA: TMPRSS11A
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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMPRSS11A (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMPRSS11A (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMPRSS11A

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TMPRSS11A

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for TMPRSS11A (Q6ZMR5³ ENSP00000334611⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
MYC	P01106³, ENSP00000367207⁴	I2D: score=1 STRING: ENSP00000367207
ZBTB17	Q13105³, ENSP00000364895⁴	I2D: score=1 STRING: ENSP00000364895

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006508	proteolysis	IEA	--
GO:0007049	cell cycle	IEA	--

TMPRSS11A for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

TMPRSS11A for compounds About GeneDecksing

EMD Millipore small molecules for TMPRSS11A:
Small Molecule - inhibitor

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TMPRSS11A
1 Novoseek chemical compound relationship for TMPRSS11A gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
serine	82.6	105	12888865 (3), 14668391 (3), 15328353 (3), 17575220 (2) (see all 77)

Search CenterWatch for drugs/clinical trials and news about TMPRSS11A / TM11A

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TMPRSS11A gene (2 alternative transcripts):

NM_001114387.1 NM_182606.3

Unigene Cluster for TMPRSS11A:

Transmembrane protease, serine 11A

Hs.450110 [show with all ESTs]

Unigene Representative Sequence: AY498712

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000508048 ENST00000334830(uc003hdr.1) ENST00000513536 ENST00000396188(uc003hds.1)

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMPRSS11A
		1 QIAGEN miScript miRNA Assays for microRNA that regulate TMPRSS11A:
		hsa-miR-1305
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMPRSS11A
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Additional cDNA sequence:

AF071882.1 AK131518.1 AK292950.1 AY498712.1 BC111796.1

1 DOTS entry:

DT.75134665

9 AceView cDNA sequences:

BN000133 BI831865 AK131518 NM_182606 AY498712 BX490784 AF071882 U77054

AW238432

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for TMPRSS11A About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8a	·	8b
SP1:			-
SP2:
SP3:			-						-

ECgene alternative splicing isoforms for TMPRSS11A

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TMPRSS11A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

TMPRSS11A expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Early limb mesenchymal cells (ELM cells) (Primary Cell)

Bone, Cartilage, Limb

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See TMPRSS11A Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.450110

UniProtKB/Swiss-Prot: TM11A_HUMAN, Q6ZMR5

Tissue specificity: Expressed in esophagus, liver, colon and lung. Down-regulated in esophagus cancers

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMPRSS11A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

--

ENSEMBL Gene Tree for TMPRSS11A (if available)
TreeFam Gene Tree for TMPRSS11A (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TMPRSS11A gene

TMPRSS7² TMPRSS5² ST14² TMPRSS4² TMPRSS11D² TMPRSS13² TMPRSS11E² TMPRSS3²

TMPRSS11B² TMPRSS2² TMPRSS9² HPN² TMPRSS15² TMPRSS11F² TMPRSS6²

18/74 SIMAP similar genes for TMPRSS11A using alignment to 4 protein entries: TM11A_HUMAN (see all proteins) (see all similar genes):

DESC1 TMPRSS11D TMPRSS11E DKFZp586F0824 HP F12

TMPRSS11F F2 TMPRSS11B HAT TMPRSS15 HPN

PROC1 TMPRSS2 PRSS22 PROC TMPRSS13 ST14

TMPRSS11A for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for TMPRSS11A
PGOHUM00000245554

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 4 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs185662471^1,2		--	68775529(+)	`AACATA/CACATA`	2	--	ds500¹		0	--	--	--	--
rs28670412^1,2	F	--	68775533(+)	`TAACAT/AAAGTA`	2	--	ds500¹		1		NA	120
rs188805790^1,2		--	68775605(+)	`AATCAA/GGTGTT`	2	--	ds500¹		0	--	--	--	--
rs74885481^1,2	C,F	--	68775617(+)	`TATGAG/CTGAAC`	2	--	ds500¹		1		NA	120
rs78792353^1,2	F	--	68775672(+)	`CAATAG/ACATGT`	2	--	ds500¹		1		WA	118
rs1440740^1,2	C,F,O,A,H	--	68775707(-)	`TGGAAC/TGATGA`	2	--	ds500¹		20		MN NS EA NA CSA WA	2526
rs181525092^1,2		--	68775807(+)	`TGCTTC/TCATAA`	2	--	ds500¹		0	--	--	--	--
rs144196567^1,2		--	68775834(+)	`TATTAC/TGAAAT`	2	--	ds500¹		0	--	--	--	--
rs1371934^1,2	C,F,O,A,H	--	68775872(-)	`CGTGTT/CTCCTG`	2	--	ds500¹		19		NS EA NA CSA WA	2414
rs147362238^1,2		--	68776059(+)	`CATTGC/TCATAA`	2	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TMPRSS11A (68775103 - 68829858 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 11 variations for TMPRSS11A
11 CNVs: 30207 8448 37549 31175 2523 9483 3498 2072 53714 80348 63851
Human Gene Mutation Database (HGMD): TMPRSS11A

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMPRSS11A

DNA2.0 Custom Variant and Variant Library Synthesis for TMPRSS11A

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TMPRSS11A for disorders           About GeneDecksing

OMIM gene information: 611704    OMIM disorders: --

20/28 diseases for TMPRSS11A (see all 28):    About MalaCards

iron-refractory iron deficiency anemia esophageal cancer esophagitis iron deficiency anemia

severe acute respiratory syndrome squamous cell carcinoma avian influenza ichthyosis, follicular

hypotrichosis ichthyosis ichthyosis with hypotrichosis oral squamous cell carcinoma

esophageal squamous cell carcinoma pancreatic ductal adenocarcinoma epithelial ovarian cancer anemia

ovarian cancer influenza prostate cancer breast cancer

6 Novoseek disease relationships for TMPRSS11A gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
cancer	35.9	14	16492908 (1), 19034347 (1), 19443387 (1), 19243302 (1) (see all 13)
metastasis	32.2	2	17575220 (1), 15792801 (1)
prostate cancer	32.2	3	12460890 (1), 18852137 (1), 15792801 (1)
tumors	22.4	11	17575220 (1), 15713998 (1), 16439987 (1), 17069593 (1) (see all 10)
carcinoma squamous cell	9.7	4	15328353 (1), 17579619 (1)
breast cancer	0	1	17985858 (1)

Human Genome Epidemiology (HuGE) Navigator: TMPRSS11A (3 documents)

Export disorders for TMPRSS11A gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TMPRSS11A gene, integrated from 9 sources (see all 91):
(articles sorted by number of sources associating them with TMPRSS11A)

Utopia: connect your pdf to the dynamic
world of online information

Mouse DESC1 is located within a cluster of seven DESC1-like genes and encodes a type II transmembrane serine protease that forms serpin inhibitory complexes. (PubMed id 15328353)^{1, 3, 9} Hobson J.P....Bugge T.H. (2004)
Induction of G1 cell cycle arrest and P15INK4b expression by ECRG1 through interaction with Miz-1. (PubMed id 15095404)^{1, 2} Zhao N.... Lu S.-H. (2004)
Human and mouse proteases: a comparative genomic approach. (PubMed id 12838346)^{1, 2} Puente X.S.... Lopez-Otin C. (2003)
ECRG1, a novel esophageal gene, cloned and identified from human esophagus and its inhibition effect on tumors. (PubMed id 17971341)^{1, 9} Yueying W....Shih-Hsin L. (2008)
A novel tumor suppressor gene ECRG4 interacts directl y with TMPRSS11A (ECRG1) to inhibit cancer cell growth in esophageal carcinoma. (PubMed id 21288367)¹ Li L.W....Lu S.H. (2011)
The ECRG1 290Arg/Gln polymorphism is related to risk o f esophageal squamous cell carcinoma in Kashmir. (PubMed id 21517269)¹ Rasool S....Masood A. (2011)
Single nucleotide polymorphism in esophageal cancer related gene 1: an analysis in resected oral squamous cell carcinoma patients. (PubMed id 19394797)¹ Blessmann M....Izbicki J.R. (2009)
Polymorphism Arg290Arg in esophageal-cancer-related gene 1 (ECRG1) is a prognostic factor for survival in esophageal cancer. (PubMed id 19052822)¹ Bachmann K....Strate T. (2009)
Candidate gene association study of esophageal squamo us cell carcinoma in a high-risk region in Iran. (PubMed id 19826048)¹ Akbari M.R....Narod S.A. (2009)
Identification of a novel polymorphism Arg290Gln of esophageal cancer related gene 1 (ECRG1) and its related risk to esophageal squamous cell carcinoma. (PubMed id 16267096)² Li Y.... Lu S.-H. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 339967	HGNC: 27954	AceView: LOC339967	Ensembl:ENSG00000187054	euGenes: HUgn339967
ECgene: TMPRSS11A	H-InvDB: TMPRSS11A

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for TMPRSS11A	Pharmacogenomics, SNPs, Pathways

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TMPRSS11A Gene

transmembrane protease, serine 11A

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TMPRSS11A Gene

transmembrane protease, serine 11A

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