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Aliases for TMPPE Gene

Aliases for TMPPE Gene

  • Transmembrane Protein With Metallophosphoesterase Domain 2 3
  • EC 3.1.-.- 4

External Ids for TMPPE Gene

Summaries for TMPPE Gene

GeneCards Summary for TMPPE Gene

TMPPE is a Protein Coding gene. GO annotations related to this gene include hydrolase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMPPE Gene

Genomics for TMPPE Gene

Genomic Location for TMPPE Gene

Start:
33,090,416 bp from pter
End:
33,096,801 bp from pter
Size:
6,386 bases
Orientation:
Minus strand

Genomic View for TMPPE Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMPPE Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMPPE Gene

Regulatory Elements for TMPPE Gene

Proteins for TMPPE Gene

  • Protein details for TMPPE Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZT21-TMPPE_HUMAN
    Recommended name:
    Transmembrane protein with metallophosphoesterase domain
    Protein Accession:
    Q6ZT21
    Secondary Accessions:
    • B2RNG5
    • Q6ZRG1

    Protein attributes for TMPPE Gene

    Size:
    453 amino acids
    Molecular mass:
    49453 Da
    Cofactor:
    Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; Note=Binds 2 divalent metal cations.;
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMPPE Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMPPE Gene

Proteomics data for TMPPE Gene at MOPED

Post-translational modifications for TMPPE Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMPPE Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMPPE Gene

Domains for TMPPE Gene

Protein Domains for TMPPE Gene

UniProtKB/Swiss-Prot:

TMPPE_HUMAN
Family:
  • Belongs to the metallophosphoesterase superfamily. LOC643853 family.:
    • Q6ZT21
genes like me logo Genes that share domains with TMPPE: view

No data available for Gene Families for TMPPE Gene

Function for TMPPE Gene

Enzyme Numbers (IUBMB) for TMPPE Gene

Gene Ontology (GO) - Molecular Function for TMPPE Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016787 hydrolase activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with TMPPE: view

No data available for Molecular function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMPPE Gene

Localization for TMPPE Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMPPE Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMPPE Gene COMPARTMENTS Subcellular localization image for TMPPE gene
Compartment Confidence
plasma membrane 3
endoplasmic reticulum 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for TMPPE Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMPPE: view

Pathways for TMPPE Gene

SuperPathways for TMPPE Gene

No Data Available

Interacting Proteins for TMPPE Gene

Gene Ontology (GO) - Biological Process for TMPPE Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with TMPPE: view

No data available for Pathways by source for TMPPE Gene

Transcripts for TMPPE Gene

mRNA/cDNA for TMPPE Gene

(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TMPPE Gene

No ASD Table

Relevant External Links for TMPPE Gene

GeneLoc Exon Structure for
TMPPE
ECgene alternative splicing isoforms for
TMPPE

Expression for TMPPE Gene

mRNA expression in normal human tissues for TMPPE Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for TMPPE Gene

genes like me logo Genes that share expressions with TMPPE: view

Orthologs for TMPPE Gene

This gene was present in the common ancestor of animals.

Orthologs for TMPPE Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMPPE 36
  • 99.34 (n)
  • 99.12 (a)
cow
(Bos Taurus)
Mammalia TMPPE 36
  • 85.29 (n)
  • 87.39 (a)
mouse
(Mus musculus)
Mammalia Tmppe 36
  • 83.52 (n)
  • 86.29 (a)
Tmppe 16
Tmppe 37
  • 86 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMPPE 37
  • 69 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC102555172 36
  • 82.55 (n)
  • 86.35 (a)
chicken
(Gallus gallus)
Aves TMPPE 36
  • 66.82 (n)
  • 69.02 (a)
zebrafish
(Danio rerio)
Actinopterygii tmppe 36
  • 58.68 (n)
  • 55.58 (a)
tmppe 37
  • 54 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea F40B5.2 36
  • 47.51 (n)
  • 37.22 (a)
F40B5.2 37
  • 32 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 46 (a)
OneToOne
Species with no ortholog for TMPPE:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for TMPPE Gene

ENSEMBL:
Gene Tree for TMPPE (if available)
TreeFam:
Gene Tree for TMPPE (if available)

Paralogs for TMPPE Gene

No data available for Paralogs for TMPPE Gene

Variants for TMPPE Gene

Relevant External Links for TMPPE Gene

HapMap Linkage Disequilibrium report
TMPPE

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for TMPPE Gene

Disorders for TMPPE Gene

No disorders were found for TMPPE Gene.

No data available for UniProtKB/Swiss-Prot for TMPPE Gene

Publications for TMPPE Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for TMPPE Gene

Sources for TMPPE Gene

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