Aliases for TMOD2 Gene
External Ids for TMOD2 Gene
Previous GeneCards Identifiers for TMOD2 Gene
This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2008]
GeneCards Summary for TMOD2 Gene
TMOD2 is a Protein Coding gene. GO annotations related to this gene include actin binding and tropomyosin binding. An important paralog of this gene is LMOD1.
UniProtKB/Swiss-Prot for TMOD2 Gene
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity).