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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMOD1 Gene

protein-coding   GIFtS: 53
GCID: GC09P100263

tropomodulin 1


(Previous symbols: D9S57E, TMOD)
 Explore 3 diseases affiliated with
TMOD1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TMOD1    

Aliases
for TMOD1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Tropomodulin 11 2     Erythrocyte Tropomodulin2 3
TMOD1 2 3 5     E-Tmod2 3
D9S57E1 2 3     E-Tropomodulin1
ETMOD1 2     Tropomodulin-11

External Ids:    HGNC: 118711   Entrez Gene: 71112   Ensembl: ENSG000001368427   OMIM: 1909305   UniProtKB: P282893   

Export aliases for TMOD1 gene to outside databases

Previous GC identifers: GC09P092029 GC09P093743 GC09P095643 GC09P095666 GC09P097343 GC09P099303 GC09P069864


Summaries
for TMOD1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TMOD1:
This gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates
tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin
filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants
encoding the same protein have been found for this gene. (provided by RefSeq, Oct 2009)

UniProtKB/Swiss-Prot: TMOD1_HUMAN, P28289
Function: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex
contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane
skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a
specific tropomyosin isoform at its N-terminus

Gene Wiki entry for TMOD1


Genomic Views
for TMOD1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_008470.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMOD1 gene promoter:
         AREB6   PPAR-gamma1   GATA-6   MyoD   PPAR-gamma2   E4BP4   FOXL1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TMOD1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TMOD1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMOD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22.3   Ensembl cytogenetic band:  9q22.33   HGNC cytogenetic band: 9q22

TMOD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMOD1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P100263:  view genomic region     (about GC identifiers)

Start:
 100,263,462 bp from pter      End:
 100,364,025 bp from pter
Size:
 100,564 bases      Orientation:
 plus strand

Proteins
for TMOD1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TMOD1_HUMAN, P28289 (See protein sequence)
Recommended Name: Tropomodulin-1  
Size: 359 amino acids; 40569 Da
Subunit: Binds to the N-terminus of isoforms 2/3 of TPM3 and to actin
Subcellular location: Cytoplasm, cytoskeleton
Secondary accessions: B2RB77 Q9BUF1

Explore the universe of human proteins at neXtProt for TMOD1: NX_P28289

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P28289

    • TMOD1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001159588.1  NP_003266.1  

    ENSEMBL proteins: 
     ENSP00000259365   ENSP00000364318   ENSP00000378637  
    Reactome Protein details: P28289
    Human Recombinant Protein Products: 
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    Novus Biologicals TMOD1 Proteins
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TMOD1

    Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0005829cytosol TAS--
    GO:0005856cytoskeleton ----
    GO:0008180colocalizes with signalosome IDA18850735


    TMOD1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for TMOD1

    Protein Domains /
    Families
    for TMOD1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TMOD1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR004934 Tropomodulin

    Graphical View of Domain Structure for InterPro Entry P28289

    ProtoNet protein and cluster: P28289

    1 Blocks protein family: IPB004934 Tropomodulin

    UniProtKB/Swiss-Prot: TMOD1_HUMAN, P28289
    Similarity: Belongs to the tropomodulin family


    Function
    for TMOD1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: TMOD1_HUMAN, P28289
    Function: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex
    contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane
    skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a
    specific tropomyosin isoform at its N-terminus

    miRNA
    Products:            		 OriGene 3'-UTR Clone (see all 2): TMOD1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMOD1
    8/51 QIAGEN miScript miRNA Assays for microRNAs that regulate TMOD1 (see all 51):
    hsa-miR-21* hsa-miR-582-3p hsa-miR-142-5p hsa-miR-3164 hsa-miR-134 hsa-miR-301a hsa-miR-124 hsa-miR-298
    SwitchGear 3'UTR luciferase reporter plasmid: TMOD1 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMOD1 (see all 7)
    OriGene shRNA RFP: TMOD1
    OriGene siRNA: TMOD1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMOD1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for TMOD1

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMOD1 (see all 4)
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    GenScript: all cDNA clones in your preferred vector (see all 2): TMOD1 (NM_003275)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMOD1 

    Cell Line
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    Search LifeMap BioReagents cell lines for TMOD1

    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--
    GO:0005523tropomyosin binding IEA--


    TMOD1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for TMOD1:
     Small cells 

    Animal Models:
         7 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Tmod1):
     cardiovascular system  embryogenesis  growth/size  hematopoietic system  homeostasis/metabolism 
     mortality/aging  muscle 

    TMOD1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for TMOD1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Striated Muscle Contraction
    		Striated Muscle Contraction1.00
    		Muscle contraction0.65
    		Striated Muscle Contraction0.87

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for TMOD1 
        Striated Muscle Contraction

    2        Reactome Pathways for TMOD1
        Muscle contraction
    Striated Muscle Contraction



    TMOD1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TMOD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/32 Interacting proteins for TMOD1 (P282893 ENSP000002593654) via UniProtKB, MINT, STRING, and/or I2D (see all 32)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NEBP209293, ENSP000003862594I2D: score=2 STRING: ENSP00000386259
    COPS5Q929053, ENSP000003505124I2D: score=1 STRING: ENSP00000350512
    TMSB10P633133, ENSP000002331434I2D: score=1 STRING: ENSP00000233143
    PRKCEQ021563I2D: score=1 
    SNX33Q8WV413I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008344adult locomotory behavior IEA--
    GO:0030049muscle filament sliding TAS--
    GO:0030239myofibril assembly IEA--


    TMOD1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TMOD1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TMOD1
    Search CenterWatch for drugs/clinical trials and news about TMOD1 

    Transcripts
    for TMOD1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TMOD1 gene (2 alternative transcripts): 
    NM_001166116.1  NM_003275.3  

    Unigene Cluster for TMOD1:

    Tropomodulin 1
    Hs.404289  [show with all ESTs]
    Unigene Representative Sequence: NM_003275
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000259365 ENST00000375175 ENST00000395211(uc004axl.2 uc004axk.2)


    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMOD1
    8/51 QIAGEN miScript miRNA Assays for microRNAs that regulate TMOD1 (see all 51):
    hsa-miR-21* hsa-miR-582-3p hsa-miR-142-5p hsa-miR-3164 hsa-miR-134 hsa-miR-301a hsa-miR-124 hsa-miR-298
    SwitchGear 3'UTR luciferase reporter plasmid: TMOD1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMOD1 (see all 7)
    OriGene shRNA RFP: TMOD1
    OriGene siRNA: TMOD1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMOD1
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMOD1 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): TMOD1 (NM_003275)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMOD1 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMOD1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMOD1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMOD1

    Additional cDNA sequence: 

    AK095748.1 AK096156.1 AK314533.1 BC002660.2 M77016.1 

    10 DOTS entries:

    DT.448680  DT.100786207  DT.447207  DT.95369662  DT.100786210  DT.100037847  DT.121158367  DT.92013476 
    DT.99997182  DT.100016606 

    24/170 AceView cDNA sequences (see all 170):

    BC002660 AW206101 BU615401 BQ926270 BX281921 CA437084 R00848 AK096156 
    AA706643 AI127379 BE857120 CA429446 BM678116 N90795 BM996455 AA455871 
    CA949991 BQ130530 BQ897320 AK095748 CD106367 BE858765 BU783086 BU742517 

    GeneLoc Exon Structure


    Expression
    for TMOD1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TMOD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTGCAGGGAC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TMOD1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeInner Nuclear LayerMature Horizontal CellsHorizontal, Retina
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    PureStem™ progenitor RASMO12 (Embryonic Progenitor Cell)
    Ventral/hypothalamic-like neurons (Generation of midbra...)
    Cardiomyocyte-like progenitor cells (Derivation of cardio...)

    See TMOD1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TMOD1

    SOURCE GeneReport for Unigene cluster: Hs.404289

    UniProtKB/Swiss-Prot: TMOD1_HUMAN, P28289
    Tissue specificity: Highly expressed in the erythrocyte, heart and skeletal muscle

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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMOD1

    Orthologs
    for TMOD1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for TMOD1 gene from 5/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves TMOD11 tropomodulin 1 77.16(n)
    86.35(a)    		   395883  NM_205027.1  NP_990358.1 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    		 --
    		 85(a)
    84(a)
    		 1 ↔ many
    1 ↔ many
    		 GL343544.1(798-34483)
    GL343391.1(1726-40906)
    zebrafish
    (Danio rerio)    		 Actinopterygii tmod11 tropomodulin 1 69.87(n)
    79.1(a)    		   100149766  XM_001920567.1  XP_001920602.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta tmod1 tropomodulin 48.87(n)
    38.35(a)    		   43633  NM_170506.3  NP_733385.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea unc-941 Protein UNC-94 47.85(n)
    40.54(a)    		   172275  NM_059333.2  NP_491734.1 


    ENSEMBL Gene Tree for TMOD1 (if available)
    TreeFam Gene Tree for TMOD1 (if available) 

    Paralogs
    for TMOD1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TMOD1 gene
    LMOD32  LMOD22  TMOD32  TMOD42  LMOD12  TMOD22  
    7 SIMAP similar genes for TMOD1 using alignment to 2 protein entries:     TMOD1_HUMAN (see all proteins):
    DKFZp686E1899    TMOD3    TMOD2    TMOD4    LMOD2    LMOD1
    LMOD3

    TMOD1 for paralogs           About GeneDecksing



    Genomic Variants
    for TMOD1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1706 NCBI SNPs in TMOD1 are shown (see all 1706)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1509264201,2
    		C,unknown100363511(+) CAATAC/TAATAT 3 -- ut310--------
    rs1501816921,2
    		--100261488(+) ACCCTG/TTCTTT 1 -- us2k10--------
    rs596946931,2
    		C--100261648(+) AAAAA-/ACAAAC 1 -- us2k11Minor allele frequency- A:0.50NA 2
    rs123469341,2
    		C,--100261656(+) AAAAAC/AAAACA 1 -- us2k1 tfbs3 trp31Minor allele frequency- A:0.50NA 2
    rs2002897181,2
    		--100261660(+) AAAAC-/AAAACA 1 -- us2k10--------
    rs108176761,2
    		C,F,A,H,--100261672(+) ACAAAC/AAAAAA 1 -- us2k1 tfbs3 trp37Minor allele frequency- A:0.29NA WA 14
    rs1158432281,2
    		F,--100261788(+) CAGCCT/CGGGCA 1 -- us2k11Minor allele frequency- C:0.04WA 118
    rs1460376181,2
    		--100261866(+) GTAATC/TCCAGC 1 -- us2k10--------
    rs792831171,2
    		F,--100261921(+) AGGAGG/ATTGAG 2 -- us2k11Minor allele frequency- A:0.08EA 120
    rs1386536391,2
    		--100261935(+) GCAATA/GAGCCG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TMOD1 (100263462 - 100364025 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TMOD1: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMOD1
    DNA2.0 Custom Variant and Variant Library Synthesis for TMOD1

    Disorders / Diseases
    for TMOD1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TMOD1 for disorders           About GeneDecksing

    OMIM gene information: 190930    OMIM disorders: --

    3 diseases for TMOD1:    About MalaCards
    transitional cell carcinoma    carcinoma    neuronitis


    Export disorders for TMOD1 gene to outside databases

    Publications
    for TMOD1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMOD1 gene, integrated from 9 sources (see all 48):
    (articles sorted by number of sources associating them with TMOD1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of human fetal liver tropomodulin. A tropomyosin-binding protein. (PubMed id 1370827)1, 2, 3, 9 Sung L.A.... Chien S. (1992)
    2. Genomic organization of mouse and human erythrocyte tropomodulin genes encoding the pointed end capping protein for the actin filaments. (PubMed id 11054557)1, 2, 9 Chu X.... Sung L.A. (2000)
    3. Erythrocyte tropomodulin binds to the N-terminus of hTM5, a tropomyosin isoform encoded by the gamma-tropomyosin gene. (PubMed id 8002995)1, 2, 9 Sung L.A. and Lin J.J.-C. (1994)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Gene assignment, expression, and homology of human tropomodulin. (PubMed id 8661028)1, 3 Sung L.A....Lin C.C. (1996)
    8. The N-terminal end of nebulin interacts with tropomodulin at the pointed ends of the thin filaments. (PubMed id 11016930)1, 9 McElhinny A.S....Gregorio C.C. (2001)
    9. Mapping the tropomyosin isoform 5 binding site on human erythrocyte tropomodulin: further insights into E-Tmod/TM5 interaction. (PubMed id 16297372)1, 9 Vera C....Sung L.A. (2005)
    10. Tropomyosin requires an intact N-terminal coiled coil to interact with tropomodulin. (PubMed id 11964245)1, 9 Greenfield N.J. and Fowler V.M. (2002)

    External Searches for TMOD1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing TMOD1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7111 HGNC: 11871 AceView: TMOD1 Ensembl:ENSG00000136842 euGenes: HUgn7111
    ECgene: TMOD1 H-InvDB: TMOD1

    Other Databases showing TMOD1 gene

    (According to HUGE)
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    Specialized Databases showing TMOD1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMOD1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TMOD1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    		Patent Information for TMOD1 gene:
    Search GeneIP for patents involving TMOD1

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