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Aliases for TMIGD1 Gene

Aliases for TMIGD1 Gene

  • Transmembrane And Immunoglobulin Domain Containing 1 2 3
  • TMIGD 3 4
  • Transmembrane And Immunoglobulin Domain-Containing Protein 1 3
  • AWKS9372 3
  • UNQ9372 3

External Ids for TMIGD1 Gene

Previous HGNC Symbols for TMIGD1 Gene


Previous GeneCards Identifiers for TMIGD1 Gene

  • GC17M025669
  • GC17M028643
  • GC17M024853

Summaries for TMIGD1 Gene

GeneCards Summary for TMIGD1 Gene

TMIGD1 is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMIGD1 Gene

Genomics for TMIGD1 Gene

Regulatory Elements for TMIGD1 Gene

Genomic Location for TMIGD1 Gene

30,316,333 bp from pter
30,334,059 bp from pter
17,727 bases
Minus strand

Genomic View for TMIGD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMIGD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMIGD1 Gene

Proteins for TMIGD1 Gene

  • Protein details for TMIGD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane and immunoglobulin domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • A8K2K1
    • Q6ZMC6

    Protein attributes for TMIGD1 Gene

    262 amino acids
    Molecular mass:
    29185 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMIGD1 Gene


neXtProt entry for TMIGD1 Gene

Proteomics data for TMIGD1 Gene at MOPED

Post-translational modifications for TMIGD1 Gene

  • Glycosylation at Asn58, Asn83, Asn118, Asn158, and Asn190
  • Modification sites at PhosphoSitePlus

Other Protein References for TMIGD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for TMIGD1

No data available for DME Specific Peptides for TMIGD1 Gene

Domains for TMIGD1 Gene

Gene Families for TMIGD1 Gene

  • IGD :Immunoglobulin superfamily / Immunoglobulin-like domain containing
  • ISET :Immunoglobulin superfamily / I-set domain containing

Protein Domains for TMIGD1 Gene

Suggested Antigen Peptide Sequences for TMIGD1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q6UXZ0
  • Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
genes like me logo Genes that share domains with TMIGD1: view

Function for TMIGD1 Gene

Gene Ontology (GO) - Molecular Function for TMIGD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with TMIGD1: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMIGD1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMIGD1 Gene

Localization for TMIGD1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMIGD1 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

Jensen Localization Image for TMIGD1 Gene COMPARTMENTS Subcellular localization image for TMIGD1 gene
Compartment Confidence
plasma membrane 3
extracellular 2
cytosol 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for TMIGD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMIGD1: view

Pathways for TMIGD1 Gene

SuperPathways for TMIGD1 Gene

No Data Available

Interacting Proteins for TMIGD1 Gene

Gene Ontology (GO) - Biological Process for TMIGD1 Gene


No data available for Pathways by source for TMIGD1 Gene

Transcripts for TMIGD1 Gene

mRNA/cDNA for TMIGD1 Gene

(5) Additional mRNA sequences :
(3) REFSEQ mRNAs :
(6) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMIGD1 Gene

Transmembrane and immunoglobulin domain containing 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMIGD1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMIGD1 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b
SP2: -

Relevant External Links for TMIGD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMIGD1 Gene

mRNA expression in normal human tissues for TMIGD1 Gene

mRNA differential expression in normal tissues according to GTEx for TMIGD1 Gene

This gene is overexpressed in Small Intestine - Terminal Ileum (27.2) and Colon - Transverse (24.9).

Protein differential expression in normal tissues for TMIGD1 Gene

This gene is overexpressed in Breast (66.5).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TMIGD1 Gene

SOURCE GeneReport for Unigene cluster for TMIGD1 Gene Hs.371005

genes like me logo Genes that share expressions with TMIGD1: view

Expression partners for TMIGD1 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TMIGD1 Gene

Orthologs for TMIGD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMIGD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TMIGD1 35
  • 83.91 (n)
  • 78.16 (a)
  • 78 (a)
(Canis familiaris)
Mammalia TMIGD1 35
  • 86.85 (n)
  • 77.39 (a)
  • 77 (a)
(Mus musculus)
Mammalia Tmigd1 35
  • 78.54 (n)
  • 73.56 (a)
Tmigd1 16
Tmigd1 36
  • 74 (a)
(Pan troglodytes)
Mammalia TMIGD1 35
  • 99.49 (n)
  • 98.85 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Tmigd1 35
  • 81.32 (n)
  • 75.4 (a)
(Monodelphis domestica)
Mammalia TMIGD1 36
  • 63 (a)
(Ornithorhynchus anatinus)
Mammalia TMIGD1 36
  • 61 (a)
(Gallus gallus)
Aves TMIGD1 35
  • 60.82 (n)
  • 53.06 (a)
  • 49 (a)
(Anolis carolinensis)
Reptilia TMIGD1 36
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tmigd1 35
  • 54.39 (n)
  • 45.18 (a)
(Danio rerio)
Actinopterygii tmigd1 35
  • 50.24 (n)
  • 35.07 (a)
tmigd1 36
  • 31 (a)
Species with no ortholog for TMIGD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMIGD1 Gene

Gene Tree for TMIGD1 (if available)
Gene Tree for TMIGD1 (if available)

Paralogs for TMIGD1 Gene

No data available for Paralogs for TMIGD1 Gene

Variants for TMIGD1 Gene

Sequence variations from dbSNP and Humsavar for TMIGD1 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs997877 -- 30,327,592(-) ACAGA(A/G)TGAGA intron-variant
rs998087 -- 30,327,652(-) AGCCC(A/G)GAAGT intron-variant
rs2321705 -- 30,326,716(+) CCTGT(A/G)CATGT intron-variant
rs2321706 -- 30,326,756(+) AAATG(C/G)TGTGT intron-variant
rs3103303 -- 30,321,911(+) GCAGC(C/G)TCGAC intron-variant

Relevant External Links for TMIGD1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMIGD1 Gene

Disorders for TMIGD1 Gene

No disorders were found for TMIGD1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TMIGD1 Gene

Publications for TMIGD1 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TMIGD1 Gene

Sources for TMIGD1 Gene

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