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Aliases for TMEM99 Gene

Aliases for TMEM99 Gene

  • Transmembrane Protein 99 2 3

External Ids for TMEM99 Gene

Previous GeneCards Identifiers for TMEM99 Gene

  • GC17P036229
  • GC17P038975
  • GC17P034769

Summaries for TMEM99 Gene

GeneCards Summary for TMEM99 Gene

TMEM99 is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM99 Gene

Genomics for TMEM99 Gene

Regulatory Elements for TMEM99 Gene

Genomic Location for TMEM99 Gene

40,819,092 bp from pter
40,836,274 bp from pter
17,183 bases
Plus strand

Genomic View for TMEM99 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM99 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM99 Gene

Proteins for TMEM99 Gene

  • Protein details for TMEM99 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 99
    Protein Accession:
    Secondary Accessions:
    • B4DQ34
    • Q96BP9

    Protein attributes for TMEM99 Gene

    258 amino acids
    Molecular mass:
    27975 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM99 Gene


neXtProt entry for TMEM99 Gene

Proteomics data for TMEM99 Gene at MOPED

Post-translational modifications for TMEM99 Gene

No Post-translational modifications

Other Protein References for TMEM99 Gene

No data available for DME Specific Peptides for TMEM99 Gene

Domains for TMEM99 Gene

Protein Domains for TMEM99 Gene


Suggested Antigen Peptide Sequences for TMEM99 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM99: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM99 Gene

Function for TMEM99 Gene

Animal Model Products

CRISPR Products

miRNA for TMEM99 Gene

miRTarBase miRNAs that target TMEM99

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM99

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM99 Gene

Localization for TMEM99 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM99 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for TMEM99 Gene COMPARTMENTS Subcellular localization image for TMEM99 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for TMEM99 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM99: view

Pathways for TMEM99 Gene

SuperPathways for TMEM99 Gene

No Data Available

Interacting Proteins for TMEM99 Gene

Gene Ontology (GO) - Biological Process for TMEM99 Gene


No data available for Pathways by source for TMEM99 Gene

Transcripts for TMEM99 Gene

Unigene Clusters for TMEM99 Gene

Transmembrane protein 99:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM99

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM99 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c
SP1: - - -
SP2: - -
SP3: -
SP4: -

Relevant External Links for TMEM99 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM99 Gene

mRNA expression in normal human tissues for TMEM99 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM99 Gene

This gene is overexpressed in Testis (6.6) and Skin - Sun Exposed (Lower leg) (4.2).

SOURCE GeneReport for Unigene cluster for TMEM99 Gene Hs.744059

genes like me logo Genes that share expressions with TMEM99: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for TMEM99 Gene

Orthologs for TMEM99 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TMEM99 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TMEM99 35
  • 98.58 (n)
  • 97.67 (a)
Species with no ortholog for TMEM99:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM99 Gene

Gene Tree for TMEM99 (if available)
Gene Tree for TMEM99 (if available)

Paralogs for TMEM99 Gene

No data available for Paralogs for TMEM99 Gene

Variants for TMEM99 Gene

Sequence variations from dbSNP and Humsavar for TMEM99 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs6694 -- 40,834,780(+) TGCGG(A/T)CATCG synonymous-codon, reference
rs10558 - 40,834,751(+) TTCGC(C/T)ATCTT missense, reference
rs1034708 -- 40,827,510(-) cttac(C/T)ctgct intron-variant, upstream-variant-2KB
rs1044806 - 40,834,800(+) AGGAC(G/T)TCTTC missense, reference
rs2240078 -- 40,834,582(-) GAGGG(C/G)ACATA synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for TMEM99 Gene

Variant ID Type Subtype PubMed ID
nsv908226 CNV Loss 21882294

Relevant External Links for TMEM99 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM99 Gene

Disorders for TMEM99 Gene

No disorders were found for TMEM99 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TMEM99 Gene

Publications for TMEM99 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Decoding the fine-scale structure of a breast cancer genome and transcriptome. (PMID: 16461635) Volik S. … Collins C. (Genome Res. 2006) 3
  5. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PMID: 16751776) Girard A. … Carmell M.A. (Nature 2006) 3

Products for TMEM99 Gene

Sources for TMEM99 Gene

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