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Aliases for TMEM94 Gene

Aliases for TMEM94 Gene

  • Transmembrane Protein 94 2 3 5
  • KIAA0195 2 3 4

External Ids for TMEM94 Gene

Previous HGNC Symbols for TMEM94 Gene

  • KIAA0195

Summaries for TMEM94 Gene

GeneCards Summary for TMEM94 Gene

TMEM94 (Transmembrane Protein 94) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM94 Gene

Genomics for TMEM94 Gene

Regulatory Elements for TMEM94 Gene

Enhancers for TMEM94 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TMEM94 on UCSC Golden Path with GeneCards custom track

Genomic Location for TMEM94 Gene

75,441,159 bp from pter
75,500,452 bp from pter
59,294 bases
Plus strand

Genomic View for TMEM94 Gene

Genes around TMEM94 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM94 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM94 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM94 Gene

Proteins for TMEM94 Gene

  • Protein details for TMEM94 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 94
    Protein Accession:
    Secondary Accessions:
    • O75536
    • Q86XF1

    Protein attributes for TMEM94 Gene

    1356 amino acids
    Molecular mass:
    151151 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA12108.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for TMEM94 Gene


neXtProt entry for TMEM94 Gene

Proteomics data for TMEM94 Gene at MOPED

Post-translational modifications for TMEM94 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TMEM94 Gene

Domains & Families for TMEM94 Gene

Protein Domains for TMEM94 Gene

Suggested Antigen Peptide Sequences for TMEM94 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM94: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM94 Gene

Function for TMEM94 Gene

genes like me logo Genes that share phenotypes with TMEM94: view

Animal Models for TMEM94 Gene

MGI Knock Outs for TMEM94:

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TMEM94 Gene

Localization for TMEM94 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM94 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM94 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with TMEM94: view

No data available for Subcellular locations from COMPARTMENTS for TMEM94 Gene

Pathways & Interactions for TMEM94 Gene

SuperPathways for TMEM94 Gene

No Data Available

Interacting Proteins for TMEM94 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000313885 Q12767-TMM94_HUMAN for TMEM94 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for TMEM94 Gene


No data available for Pathways by source and SIGNOR curated interactions for TMEM94 Gene

Drugs & Compounds for TMEM94 Gene

No Compound Related Data Available

Transcripts for TMEM94 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM94 Gene

No ASD Table

Relevant External Links for TMEM94 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM94 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA Expression by UniProt/SwissProt for TMEM94 Gene

Tissue specificity: Expressed ubiquitously.
genes like me logo Genes that share expression patterns with TMEM94: view

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for TMEM94 Gene

Orthologs for TMEM94 Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM94 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia KIAA0195 35
  • 90.36 (n)
  • 94.21 (a)
KIAA0195 36
  • 93 (a)
(Canis familiaris)
Mammalia KIAA0195 35
  • 90.81 (n)
  • 95.8 (a)
KIAA0195 36
  • 95 (a)
(Mus musculus)
Mammalia 2310067B10Rik 35
  • 89.28 (n)
  • 95.5 (a)
Tmem94 16
2310067B10Rik 36
  • 95 (a)
(Pan troglodytes)
Mammalia KIAA0195 35
  • 99.63 (n)
  • 99.63 (a)
KIAA0195 36
  • 98 (a)
(Monodelphis domestica)
Mammalia KIAA0195 36
  • 90 (a)
(Ornithorhynchus anatinus)
Mammalia KIAA0195 36
  • 84 (a)
(Gallus gallus)
Aves KIAA0195 35
  • 75.98 (n)
  • 82.77 (a)
KIAA0195 36
  • 83 (a)
(Anolis carolinensis)
Reptilia KIAA0195 36
  • 81 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa0195 35
  • 70.58 (n)
  • 71.99 (a)
(Danio rerio)
Actinopterygii LOC795408 35
  • 67.47 (n)
  • 69.13 (a)
si:dkeyp-67e6.4 36
  • 68 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000576 35
  • 50.34 (n)
  • 38.27 (a)
fruit fly
(Drosophila melanogaster)
Insecta l(2)k05819 35
  • 48.98 (n)
  • 37.58 (a)
l(2)k05819 36
  • 30 (a)
(Caenorhabditis elegans)
Secernentea D1007.15 35
  • 41.03 (n)
  • 33.06 (a)
D1007.15 36
  • 27 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 28 (a)
-- 36
  • 23 (a)
Species with no ortholog for TMEM94:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TMEM94 Gene

Gene Tree for TMEM94 (if available)
Gene Tree for TMEM94 (if available)

Paralogs for TMEM94 Gene

No data available for Paralogs for TMEM94 Gene

Variants for TMEM94 Gene

Sequence variations from dbSNP and Humsavar for TMEM94 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs8073809 - 75,496,347(+) CAGCA(C/T)CAGCA reference, missense
rs13357 -- 75,499,611(-) TTAGG(C/G)CCCCT utr-variant-3-prime
rs4073989 -- 75,454,781(+) AGGGA(A/G)Aggct intron-variant, upstream-variant-2KB
rs4073990 -- 75,454,843(+) GAGGA(C/T)TGCTT intron-variant, upstream-variant-2KB
rs4073991 -- 75,455,388(-) tgatt(C/T)tcttg intron-variant, upstream-variant-2KB

Variation tolerance for TMEM94 Gene

Residual Variation Intolerance Score: 5.42% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.17; 39.28% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for TMEM94 Gene

Disorders for TMEM94 Gene

Relevant External Links for TMEM94

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TMEM94 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM94 Gene

Publications for TMEM94 Gene

  1. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PMID: 8724849) Nagase T. … Nomura N. (DNA Res. 1996) 2 3 4 67
  2. Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy. (PMID: 25852190) So J. … Colwill K. (Sci Signal 2015) 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PMID: 23455922) Varjosalo M. … Superti-Furga G. (Nat. Methods 2013) 3
  5. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 3

Products for TMEM94 Gene

Sources for TMEM94 Gene