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Aliases for TMEM92 Gene

Aliases for TMEM92 Gene

  • Transmembrane Protein 92 2 3 5

External Ids for TMEM92 Gene

Previous GeneCards Identifiers for TMEM92 Gene

  • GC17P045707
  • GC17P048352
  • GC17P043718

Summaries for TMEM92 Gene

GeneCards Summary for TMEM92 Gene

TMEM92 (Transmembrane Protein 92) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM92 Gene

Genomics for TMEM92 Gene

Regulatory Elements for TMEM92 Gene

Genomic Location for TMEM92 Gene

50,271,406 bp from pter
50,281,485 bp from pter
10,080 bases
Plus strand

Genomic View for TMEM92 Gene

Genes around TMEM92 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM92 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM92 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM92 Gene

Proteins for TMEM92 Gene

  • Protein details for TMEM92 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 92
    Protein Accession:
    Secondary Accessions:
    • Q8NBF0

    Protein attributes for TMEM92 Gene

    159 amino acids
    Molecular mass:
    17229 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM92 Gene

Proteomics data for TMEM92 Gene at MOPED

Post-translational modifications for TMEM92 Gene

No Post-translational modifications

Other Protein References for TMEM92 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM92 Gene

Domains & Families for TMEM92 Gene

Protein Domains for TMEM92 Gene


Suggested Antigen Peptide Sequences for TMEM92 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM92: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM92 Gene

Function for TMEM92 Gene

genes like me logo Genes that share phenotypes with TMEM92: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM92 Gene

Localization for TMEM92 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM92 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

Jensen Localization Image for TMEM92 Gene COMPARTMENTS Subcellular localization image for TMEM92 gene
Compartment Confidence
plasma membrane 3
extracellular 1

No data available for Gene Ontology (GO) - Cellular Components for TMEM92 Gene

Pathways & Interactions for TMEM92 Gene

SuperPathways for TMEM92 Gene

No Data Available

Interacting Proteins for TMEM92 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000300433 for TMEM92 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for TMEM92 Gene


No data available for Pathways by source and SIGNOR curated interactions for TMEM92 Gene

Drugs & Compounds for TMEM92 Gene

No Compound Related Data Available

Transcripts for TMEM92 Gene

Unigene Clusters for TMEM92 Gene

Transmembrane protein 92:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM92 Gene

No ASD Table

Relevant External Links for TMEM92 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM92 Gene

mRNA expression in normal human tissues for TMEM92 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM92 Gene

This gene is overexpressed in Stomach (x13.6), Small Intestine - Terminal Ileum (x9.8), and Liver (x6.6).

SOURCE GeneReport for Unigene cluster for TMEM92 Gene Hs.224630

genes like me logo Genes that share expression patterns with TMEM92: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TMEM92 Gene

Orthologs for TMEM92 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TMEM92 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia TMEM92 35
  • 76.65 (n)
  • 66.24 (a)
TMEM92 36
  • 58 (a)
(Pan troglodytes)
Mammalia LOC747062 35
  • 96.99 (n)
  • 95.14 (a)
TMEM92 36
  • 98 (a)
(Bos Taurus)
Mammalia TMEM92 36
  • 58 (a)
(Monodelphis domestica)
Mammalia TMEM92 36
  • 45 (a)
(Mus musculus)
Mammalia Tmem92 36
  • 41 (a)
Species with no ortholog for TMEM92:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM92 Gene

Gene Tree for TMEM92 (if available)
Gene Tree for TMEM92 (if available)

Paralogs for TMEM92 Gene Pseudogenes for TMEM92 Gene

genes like me logo Genes that share paralogs with TMEM92: view

No data available for Paralogs for TMEM92 Gene

Variants for TMEM92 Gene

Sequence variations from dbSNP and Humsavar for TMEM92 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs6504642 -, - 50,278,899(+) AGACA(A/C/G)CCCAG reference, missense
rs9894445 - 50,274,511(+) CCCAA(A/G)CTTGG reference, missense
rs1969512 -- 50,280,055(-) ACCCA(A/C)ACAAG utr-variant-3-prime
rs1969513 -- 50,279,939(-) GACTG(G/T)CCTCC utr-variant-3-prime
rs2141280 -- 50,271,889(-) ctaat(A/T)ttttg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM92 Gene

Variant ID Type Subtype PubMed ID
nsv833475 CNV Loss 17160897
nsv509661 CNV Insertion 20534489

Variation tolerance for TMEM92 Gene

Residual Variation Intolerance Score: 48.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.14; 51.51% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM92 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM92 Gene

Disorders for TMEM92 Gene

Relevant External Links for TMEM92

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TMEM92 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM92 Gene

Publications for TMEM92 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PMID: 23824909) Chen Y. … Ge F. (Mol. Cell Proteomics 2013) 3
  4. Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. (PMID: 19834535) Wheeler H.E. … Kim S.K. (PLoS Genet. 2009) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for TMEM92 Gene

Sources for TMEM92 Gene

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