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TMEM9 Gene

protein-coding   GIFtS: 53
GCID: GC01M201103

Transmembrane Protein 9

  See TMEM9-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Protein 91 2
Dermal Papilla-Derived Protein 42 3
TMEM9A2
DERP43
SYNDIG15
TMEM90B5

External Ids:    HGNC: 188231   Entrez Gene: 2528392   Ensembl: ENSG000001168577   OMIM: 6143115   UniProtKB: Q9P0T73   

Export aliases for TMEM9 gene to outside databases

Previous GC identifers: GC00U991238 GC01M196562 GC01M197570 GC01M198392 GC01M197835 GC01M199370 GC01M172270


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEM9 Gene:
TMEM9 (transmembrane protein 9) is a protein-coding gene. Diseases associated with TMEM9 include exfoliation syndrome. An important paralog of this gene is TMEM9B.

UniProtKB/Swiss-Prot: TMEM9_HUMAN, Q9P0T7
Function: May be involved in intracellular transport

Gene Wiki entry for TMEM9 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_004487.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM9 gene promoter:
         Spz1   Tal-1   AML1a   FOXO3   Lmo2   FOXO3b   FAC1   FOXO4   FOXO3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TMEM9 promoter sequence
   Search Chromatin IP Primers for TMEM9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Ensembl cytogenetic band:  1q32.1   HGNC cytogenetic band: 1q41

TMEM9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM9 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M201103:  view genomic region     (about GC identifiers)

Start:
201,103,900 bp from pter      End:
201,140,702 bp from pter
Size:
36,803 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TMEM9_HUMAN, Q9P0T7 (See protein sequence)
Recommended Name: Transmembrane protein 9 precursor  
Size: 183 amino acids; 20574 Da
Subunit: Dimer (Potential)
Secondary accessions: B1ALM6 Q96NQ9 Q9BQF5

Explore the universe of human proteins at neXtProt for TMEM9: NX_Q9P0T7

Explore proteomics data for TMEM9 at MOPED

Post-translational modifications: 

  • N-glycosylated1
  • Glycosylation2 at Asn21, Asn38, Asn47
  • Modification sites at PhosphoSitePlus

  • See TMEM9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (9 alternative transcripts): 
    NP_001275493.1  NP_001275494.1  NP_001275495.1  NP_001275496.1  NP_001275497.1  NP_001275498.1  NP_001275499.1  NP_001275500.1  
    NP_057540.1  

    ENSEMBL proteins: 
     ENSP00000356303   ENSP00000356302   ENSP00000356299   ENSP00000356301   ENSP00000476893  
     ENSP00000437181   ENSP00000405329   ENSP00000390184   ENSP00000398557  

    TMEM9 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for TMEM9

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR008853 TMEM9

    Graphical View of Domain Structure for InterPro Entry Q9P0T7

    ProtoNet protein and cluster: Q9P0T7

    1 Blocks protein domain: IPB008853 TMEM9

    UniProtKB/Swiss-Prot: TMEM9_HUMAN, Q9P0T7
    Similarity: Belongs to the TMEM9 family


    Find genes that share domains with TMEM9           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TMEM9_HUMAN, Q9P0T7
    Function: May be involved in intracellular transport

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    Find genes that share ontologies with TMEM9           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for TMEM9:
     Decreased cell number, increas  G0/1 arrest 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM9
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM9
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM9

    miRNA
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    miRTarBase miRNAs that target TMEM9:
    hsa-mir-17-5p (MIRT050914), hsa-mir-125b-5p (MIRT046083)

    Block miRNA regulation of human, mouse, rat TMEM9 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate TMEM9:
    hsa-miR-135b hsa-miR-136 hsa-miR-24 hsa-miR-135a
    SwitchGear 3'UTR luciferase reporter plasmidTMEM9 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TMEM9

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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM9

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM9


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TMEM9_HUMAN, Q9P0T7: Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass
    type I membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome5
    lysosome5
    vacuole5
    extracellular2
    plasma membrane2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005764lysosome IDA12359240
    GO:0005765lysosomal membrane IEA--
    GO:0005770late endosome IDA12359240
    GO:0016021integral component of membrane IEA--
    GO:0031902late endosome membrane IEA--

    Find genes that share ontologies with TMEM9           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM9
    Interactions:

        Search GeneGlobe Interaction Network for TMEM9

    2 Interacting proteins for TMEM9 (Q9P0T73) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TMEM230Q96A573I2D: score=3 
    CLN3Q132863I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport IEA--
    GO:0008150biological_process ND--

    Find genes that share ontologies with TMEM9           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM9



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TMEM9 gene (9 alternative transcripts): 
    NM_001288564.1  NM_001288565.1  NM_001288566.1  NM_001288567.1  NM_001288568.1  NM_001288569.1  NM_001288570.1  NM_001288571.1  
    NM_016456.4  

    Unigene Cluster for TMEM9:

    Transmembrane protein 9
    Hs.181444  [show with all ESTs]
    Unigene Representative Sequence: AK094588
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367334 ENST00000367333(uc001gwa.3) ENST00000472411 ENST00000367330(uc001gvx.3)
    ENST00000367332(uc001gvy.3 uc010ppo.2 uc001gvz.3 uc010ppp.1)
    ENST00000495205 ENST00000485839 ENST00000497582 ENST00000455367 ENST00000435310
    ENST00000414605
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM9 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate TMEM9:
    hsa-miR-135b hsa-miR-136 hsa-miR-24 hsa-miR-135a
    SwitchGear 3'UTR luciferase reporter plasmidTMEM9 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM9
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM9
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TMEM9 (NM_001033504)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM9
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM9
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM9
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM9
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM9
      QuantiFast Probe-based Assays in human, mouse, rat TMEM9

    Additional mRNA sequence: 

    AB013909.1 AF151020.1 AK054883.1 AK075335.1 AK091726.1 AK094588.1 AK296307.1 AK303843.1 
    AL136600.1 AY138587.1 AY359012.1 BC001106.2 CR457162.1 CR533467.1 

    18 DOTS entries:

    DT.447561  DT.101962517  DT.100827520  DT.100827515  DT.101982822  DT.99980739  DT.100827516  DT.100671856 
    DT.100827510  DT.121409511  DT.100043099  DT.121409551  DT.100044830  DT.100827514  DT.100827525  DT.95266638 
    DT.95266639  DT.97860052 

    Selected AceView cDNA sequences (see all 592):

    CF528592 CR617609 CR618141 AI190982 AA911959 BE220528 AI538649 BM837202 
    AI660327 AI422274 BM672144 CR615799 AK054883 BM703587 AW005478 BF437577 
    BI771068 AI869084 CR600811 F04350 CR594211 CR620935 BP382044 BM547719 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TMEM9 (see all 10)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c · 9d · 9e
    SP1:                    -     -                 -                       -     -     -                                       
    SP2:                    -     -           -     -                       -     -     -                                       
    SP3:                                      -     -                       -     -     -                                       
    SP4:                                      -     -                       -     -                                             
    SP5:        -     -     -     -           -     -                       -     -     -                                       


    ECgene alternative splicing isoforms for TMEM9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMEM9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGAGAAAAT
    TMEM9 Expression
    About this image


    TMEM9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Eye (Sensory Organs)
             Retina
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Kidney (Urinary System)
     
     Uterus (Reproductive System)
     
     Thyroid (Endocrine System)
    TMEM9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.181444

    UniProtKB/Swiss-Prot: TMEM9_HUMAN, Q9P0T7
    Tissue specificity: Highly expressed in adrenal gland, thyroid gland, testis, ovary and prostate. Moderate
    expression in trachea, spinal cord, stomach, colon, small intestine and spleen. Low expression in bone marrow,
    lymph node, thymus and peripheral blood lymphocytes. Expression was detected in hematopoietic cell lines
    including those of myeloid, erythroid, B- and T-cell origin

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TMEM9 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem91 , 5 transmembrane protein 91, 5 90.89(n)1
    97.27(a)1
      1 (59.51 cM)5
    662411  NM_001160145.11  NP_001153617.11 
     1360179675 
    chicken
    (Gallus gallus)
    Aves TMEM91 transmembrane protein 9 80.6(n)
    87.01(a)
      421157  XM_004934842.1  XP_004934899.1 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM96
    transmembrane protein 9
    67(a)
    1 ↔ 1
    4(131068749-131098371)
    zebrafish
    (Danio rerio)
    Actinopterygii wufi33g112 wufi33g11 81.23(n)   334151  BC045338.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG11611 CG1161 47.07(n)
    33.94(a)
      40638  NM_141271.3  NP_649528.2 
    worm
    (Caenorhabditis elegans)
    Secernentea R12C12.61 R12C12.6 46.63(n)
    33.33(a)
      187840  NM_001047331.3  NP_001040796.1 


    ENSEMBL Gene Tree for TMEM9 (if available)
    TreeFam Gene Tree for TMEM9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TMEM9 gene
    TMEM9B2  
    1 SIMAP similar gene for TMEM9 using alignment to 8 protein entries:     TMEM9_HUMAN (see all proteins):
    TMEM9B

    Find genes that share paralogs with TMEM9           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TMEM9 (see all 523)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1391088851,2
    --172270021(+) CTGACA/GCAGTG 1 -- int10--------
    rs174554551,2
    C,F,H--201103404(+) AGTGCC/TGGGCT 1 -- int123Minor allele frequency- T:0.18NA NS EA WA 2484
    rs1844623171,2
    --201103405(+) GTGCCA/GGGCTC 1 -- int10--------
    rs1494826871,2
    C--201103437(+) CTGCTA/GGCATT 1 -- int10--------
    rs1888587221,2
    --201103453(+) CTGTAC/TGGGGC 1 -- int10--------
    rs615934041,2
    C,F--201103464(+) AGCTCG/ATTTTC 1 -- int17Minor allele frequency- A:0.34WA NA CSA EA 366
    rs783712161,2
    C,F--201103489(+) CACCCC/TTCTCC 1 -- int11Minor allele frequency- T:0.08WA 118
    rs1820370101,2
    C--201103545(+) GGAGCA/GCTATT 1 -- int10--------
    rs758769521,2
    F--201103571(+) ATATTA/CGGATG 1 -- int11Minor allele frequency- C:0.03WA 118
    rs1140855261,2
    F--201103583(+) ATCACG/ACACTG 1 -- int11Minor allele frequency- A:0.02NA 120

    HapMap Linkage Disequilibrium report for TMEM9 (201103900 - 201140702 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TMEM9:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv428301CNV Gain18775914

    Human Gene Mutation Database (HGMD): TMEM9
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM9
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614311    OMIM disorders: --

    1 disease for TMEM9:    
    About MalaCards
    exfoliation syndrome

    1 disease from the University of Copenhagen DISEASES database for TMEM9:
    Exfoliation syndrome

    Find genes that share disorders with TMEM9           About GenesLikeMe

    Genetic Association Database (GAD): TMEM9
    Human Genome Epidemiology (HuGE) Navigator: TMEM9 (1 document)

    Export disorders for TMEM9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMEM9 gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with TMEM9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (DNA Res. 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    6. Characterization of the novel human transmembrane protein 9 (TMEM9) that localizes to lysosomes and late endosomes. (PubMed id 12359240)1, 2 Kveine M.... Rian E. (Biochem. Biophys. Res. Commun. 2002)
    7. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    8. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    9. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    10. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 252839 HGNC: 18823 AceView: TMEM9 Ensembl:ENSG00000116857 euGenes: HUgn252839
    ECgene: TMEM9 H-InvDB: TMEM9

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TMEM9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TMEM9 gene:
    Search GeneIP for patents involving TMEM9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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