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Aliases for TMEM88B Gene

Aliases for TMEM88B Gene

  • Transmembrane Protein 88B 2 3

External Ids for TMEM88B Gene

Summaries for TMEM88B Gene

GeneCards Summary for TMEM88B Gene

TMEM88B is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM88B Gene

Genomics for TMEM88B Gene

Genomic Location for TMEM88B Gene

Start:
1,426,128 bp from pter
End:
1,427,787 bp from pter
Size:
1,660 bases
Orientation:
Plus strand

Genomic View for TMEM88B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM88B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM88B Gene

Regulatory Elements for TMEM88B Gene

Proteins for TMEM88B Gene

  • Protein details for TMEM88B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NKF7-TM88B_HUMAN
    Recommended name:
    Transmembrane protein 88B
    Protein Accession:
    A6NKF7
    Secondary Accessions:

    Protein attributes for TMEM88B Gene

    Size:
    163 amino acids
    Molecular mass:
    17097 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM88B Gene

Proteomics data for TMEM88B Gene at MOPED

Post-translational modifications for TMEM88B Gene

No Post-translational modifications

Other Protein References for TMEM88B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM88B Gene

Domains for TMEM88B Gene

Protein Domains for TMEM88B Gene

ProtoNet:

UniProtKB/Swiss-Prot:

TM88B_HUMAN
Family:
  • Belongs to the TMEM88 family.:
    • A6NKF7
genes like me logo Genes that share domains with TMEM88B: view

No data available for Gene Families for TMEM88B Gene

Function for TMEM88B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM88B Gene

Localization for TMEM88B Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM88B Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM88B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM88B: view

Pathways for TMEM88B Gene

SuperPathways for TMEM88B Gene

No Data Available

Interacting Proteins for TMEM88B Gene

Gene Ontology (GO) - Biological Process for TMEM88B Gene

None

No data available for Pathways by source for TMEM88B Gene

Transcripts for TMEM88B Gene

mRNA/cDNA for TMEM88B Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM88B Gene

Transmembrane protein 88B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM88B Gene

No ASD Table

Relevant External Links for TMEM88B Gene

GeneLoc Exon Structure for
TMEM88B
ECgene alternative splicing isoforms for
TMEM88B

Expression for TMEM88B Gene

mRNA expression in normal human tissues for TMEM88B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM88B Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (12.7), Brain - Substantia nigra (8.1), Brain - Hippocampus (5.4), Brain - Putamen (basal ganglia) (4.3), Brain - Hypothalamus (4.3), and Brain - Amygdala (4.1).

SOURCE GeneReport for Unigene cluster for TMEM88B Gene Hs.729765

genes like me logo Genes that share expressions with TMEM88B: view

Orthologs for TMEM88B Gene

This gene was present in the common ancestor of mammals.

Orthologs for TMEM88B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TMEM88B 36
  • 81.97 (n)
  • 76.1 (a)
TMEM88B 37
  • 73 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM88B 36
  • 79.56 (n)
  • 79.33 (a)
TMEM88B 37
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem88b 36
  • 71.66 (n)
  • 70.75 (a)
Tmem88b 16
Tmem88b 37
  • 69 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem88b 36
  • 73.74 (n)
  • 69.86 (a)
Species with no ortholog for TMEM88B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM88B Gene

ENSEMBL:
Gene Tree for TMEM88B (if available)
TreeFam:
Gene Tree for TMEM88B (if available)

Paralogs for TMEM88B Gene

No data available for Paralogs for TMEM88B Gene

Variants for TMEM88B Gene

Sequence variations from dbSNP and Humsavar for TMEM88B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1695848 -- 1,426,175(-) GAAGC(A/G)CCACC synonymous-codon, reference
rs1781136 -- 1,424,220(+) TGCCC(A/G)GCGCT upstream-variant-2KB
rs1781137 -- 1,426,810(+) GCCTG(C/G)TCTGG intron-variant
rs2801380 -- 1,425,013(-) GACTC(A/G)ATCAG upstream-variant-2KB
rs2801381 -- 1,424,727(-) ttttt(G/T)tcgag upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TMEM88B Gene

Variant ID Type Subtype PubMed ID
nsv10161 CNV Gain+Loss 18304495
dgv2n67 CNV Gain 20364138
dgv10n71 CNV Loss 21882294
dgv12n71 CNV Loss 21882294
dgv19n71 CNV Loss 21882294
dgv20n71 CNV Loss 21882294
dgv25n71 CNV Loss 21882294
dgv30n71 CNV Gain 21882294
dgv31n71 CNV Gain 21882294
dgv32n71 CNV Gain+Loss 21882294
dgv33n71 CNV Loss 21882294
dgv34n71 CNV Loss 21882294
dgv38n71 CNV Loss 21882294
nsv871837 CNV Loss 21882294
nsv871690 CNV Gain 21882294
essv5472 CNV CNV 17122850
dgv9e1 CNV Complex 17122850
dgv40n71 CNV Loss 21882294
nsv871787 CNV Loss 21882294
esv24333 CNV Gain 19812545

Relevant External Links for TMEM88B Gene

HapMap Linkage Disequilibrium report
TMEM88B

Disorders for TMEM88B Gene

No disorders were found for TMEM88B Gene.

No data available for UniProtKB/Swiss-Prot for TMEM88B Gene

Publications for TMEM88B Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4

Products for TMEM88B Gene

Sources for TMEM88B Gene

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