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Aliases for TMEM87A Gene

Aliases for TMEM87A Gene

  • Transmembrane Protein 87A 2 3

External Ids for TMEM87A Gene

Summaries for TMEM87A Gene

GeneCards Summary for TMEM87A Gene

TMEM87A is a Protein Coding gene. An important paralog of this gene is TMEM87B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM87A Gene

Genomics for TMEM87A Gene

Genomic Location for TMEM87A Gene

Start:
42,210,452 bp from pter
End:
42,273,663 bp from pter
Size:
63,212 bases
Orientation:
Minus strand

Genomic View for TMEM87A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM87A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM87A Gene

Proteins for TMEM87A Gene

  • Protein details for TMEM87A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NBN3-TM87A_HUMAN
    Recommended name:
    Transmembrane protein 87A
    Protein Accession:
    Q8NBN3
    Secondary Accessions:
    • Q6NT77
    • Q8NCA4
    • Q9BS46
    • Q9P103
    • Q9Y3Y7

    Protein attributes for TMEM87A Gene

    Size:
    555 amino acids
    Molecular mass:
    63430 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC11598.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for TMEM87A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMEM87A Gene

Proteomics data for TMEM87A Gene at MOPED

Post-translational modifications for TMEM87A Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys397 and Lys484
  • Glycosylation at Asn79, Asn127, Asn157, and Asn160

No data available for DME Specific Peptides for TMEM87A Gene

Domains for TMEM87A Gene

Protein Domains for TMEM87A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM87A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NBN3

UniProtKB/Swiss-Prot:

TM87A_HUMAN
Family:
  • Belongs to the LU7TM family. TMEM87 subfamily.:
    • Q8NBN3
genes like me logo Genes that share domains with TMEM87A: view

No data available for Gene Families for TMEM87A Gene

Function for TMEM87A Gene

miRNA for TMEM87A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM87A Gene

Localization for TMEM87A Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM87A Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM87A Gene COMPARTMENTS Subcellular localization image for TMEM87A gene
Compartment Confidence
golgi apparatus 4
nucleus 4
plasma membrane 3
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for TMEM87A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM87A: view

Pathways for TMEM87A Gene

SuperPathways for TMEM87A Gene

No Data Available

Interacting Proteins for TMEM87A Gene

Gene Ontology (GO) - Biological Process for TMEM87A Gene

None

No data available for Pathways by source for TMEM87A Gene

Transcripts for TMEM87A Gene

Unigene Clusters for TMEM87A Gene

Transmembrane protein 87A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM87A Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20
SP1: -
SP2: - -
SP3:

Relevant External Links for TMEM87A Gene

GeneLoc Exon Structure for
TMEM87A
ECgene alternative splicing isoforms for
TMEM87A

Expression for TMEM87A Gene

mRNA expression in normal human tissues for TMEM87A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMEM87A Gene

SOURCE GeneReport for Unigene cluster for TMEM87A Gene Hs.744941

genes like me logo Genes that share expressions with TMEM87A: view

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TMEM87A Gene

Orthologs for TMEM87A Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TMEM87A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM87A 35
  • 99.82 (n)
  • 99.82 (a)
TMEM87A 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM87A 35
  • 92.61 (n)
  • 94.77 (a)
TMEM87A 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM87A 35
  • 93.45 (n)
  • 95.5 (a)
mouse
(Mus musculus)
Mammalia Tmem87a 35
  • 89.23 (n)
  • 92.78 (a)
Tmem87a 16
Tmem87a 36
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM87A 36
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM87A 36
  • 41 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem87a 35
  • 87.75 (n)
  • 90.45 (a)
chicken
(Gallus gallus)
Aves TMEM87A 35
  • 75.84 (n)
  • 80.11 (a)
TMEM87A 36
  • 75 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM87A 36
  • 73 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem87a 35
  • 68.53 (n)
  • 71.81 (a)
zebrafish
(Danio rerio)
Actinopterygii -- 35
TMEM87A 36
  • 47 (a)
OneToOne
zgc:162698 35
  • 59.7 (n)
  • 54.1 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG17660 36
  • 39 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea C52B9.4 36
  • 31 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 14 (a)
ManyToMany
PTM1 36
  • 17 (a)
ManyToMany
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.3403 35
Species with no ortholog for TMEM87A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TMEM87A Gene

ENSEMBL:
Gene Tree for TMEM87A (if available)
TreeFam:
Gene Tree for TMEM87A (if available)

Paralogs for TMEM87A Gene

Paralogs for TMEM87A Gene

Selected SIMAP similar genes for TMEM87A Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with TMEM87A: view

Variants for TMEM87A Gene

Sequence variations from dbSNP and Humsavar for TMEM87A Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs8108 -- 42,210,698(+) ACCAG(A/T)TACCA utr-variant-3-prime
rs603468 -- 42,213,837(+) GAAAA(C/T)AGAGA intron-variant
rs607959 -- 42,216,329(-) GTATT(A/G)TTACG intron-variant
rs613090 -- 42,220,731(-) GAGCT(A/G)CTTTG intron-variant
rs618161 -- 42,214,822(+) CAAAA(C/G)AAGAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM87A Gene

Variant ID Type Subtype PubMed ID
nsv471683 CNV Gain+Loss 15918152
nsv832985 CNV Loss 17160897
nsv827308 CNV Gain 20364138
nsv904133 CNV Gain 21882294
esv1006302 CNV Deletion 20482838
nsv827310 CNV Loss 20364138

Relevant External Links for TMEM87A Gene

HapMap Linkage Disequilibrium report
TMEM87A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM87A Gene

Disorders for TMEM87A Gene

Relevant External Links for TMEM87A

Genetic Association Database (GAD)
TMEM87A
genes like me logo Genes that share disorders with TMEM87A: view

No data available for UniProtKB/Swiss-Prot for TMEM87A Gene

Publications for TMEM87A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PMID: 16303743) Otsuki T. … Isogai T. (DNA Res. 2005) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Human GPR107 and murine Gpr108 are members of the LUSTR family of proteins found in both plants and animals, having similar topology to G-protein coupled receptors. (PMID: 17454009) Edgar A.J. (DNA Seq. 2007) 23

Products for TMEM87A Gene

Sources for TMEM87A Gene

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