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TMEM87A Gene

protein-coding   GIFtS: 46
GCID: GC15M042502

Transmembrane Protein 87A

  See TMEM87A-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Protein 87A1 2

External Ids:    HGNC: 245221   Entrez Gene: 259632   Ensembl: ENSG000001039787   UniProtKB: Q8NBN33   

Export aliases for TMEM87A gene to outside databases

Previous GC identifers: GC15M040291 GC15M019350


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEM87A Gene:
TMEM87A (transmembrane protein 87A) is a protein-coding gene. Diseases associated with TMEM87A include congenital dyserythropoietic anemia type i. An important paralog of this gene is TMEM87B.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM87A gene promoter:
         LHX3b/Lhx3b   Pax-6   POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   POU3F2   GATA-1   POU2F1   POU2F1a   LHX3a/Lhx3a   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM87A promoter sequence
   Search Chromatin IP Primers for TMEM87A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM87A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15.1   Ensembl cytogenetic band:  15q15.1   HGNC cytogenetic band: 15q15.1

TMEM87A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM87A gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M042502:  view genomic region     (about GC identifiers)

Start:
42,502,726 bp from pter      End:
42,565,861 bp from pter
Size:
63,136 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TM87A_HUMAN, Q8NBN3 (See protein sequence)
Recommended Name: Transmembrane protein 87A precursor  
Size: 555 amino acids; 63430 Da
Sequence caution: Sequence=BAC11598.1; Type=Erroneous initiation;
Secondary accessions: Q6NT77 Q8NCA4 Q9BS46 Q9P103 Q9Y3Y7
Alternative splicing: 3 isoforms:  Q8NBN3-1   Q8NBN3-2   Q8NBN3-3   

Explore the universe of human proteins at neXtProt for TMEM87A: NX_Q8NBN3

Explore proteomics data for TMEM87A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys397, Lys484
  • Glycosylation2 at Asn79, Asn127, Asn157, Asn160
  • Modification sites at PhosphoSitePlus

  • See TMEM87A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001103973.1  NP_001273416.1  NP_056312.2  

    ENSEMBL proteins: 
     ENSP00000374484   ENSP00000457308   ENSP00000456225   ENSP00000454539   ENSP00000455343  
     ENSP00000457874   ENSP00000454278   ENSP00000305894   ENSP00000456940   ENSP00000405379  

    TMEM87A Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for TMEM87A
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    Novus Biologicals TMEM87A Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for TMEM87A 

     
    Search antibodies-online for proteins for TMEM87A 

     
    Search antibodies-online for peptides for TMEM87A

    TMEM87A Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals TMEM87A Antibodies
    Abcam antibodies for TMEM87A
    Browse Antibodies at Cloud-Clone Corp.
    Search ThermoFisher Antibodies for TMEM87A
    Search antibodies-online for antibodies for TMEM87A 

    TMEM87A Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for TMEM87A 
    antibodies-online kits for TMEM87A (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR009637 TM_rcpt_euk

    Graphical View of Domain Structure for InterPro Entry Q8NBN3

    ProtoNet protein and cluster: Q8NBN3

    UniProtKB/Swiss-Prot: TM87A_HUMAN, Q8NBN3
    Similarity: Belongs to the LU7TM family. TMEM87 subfamily


    Find genes that share domains with TMEM87A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TMEM87A

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM87A:
    hsa-mir-1 (MIRT023768), hsa-mir-16-5p (MIRT031706), hsa-mir-19a-3p (MIRT050644), hsa-mir-107 (MIRT048311), hsa-mir-30a-5p (MIRT005124)

    Block miRNA regulation of human, mouse, rat TMEM87A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM87A (see all 41):
    hsa-miR-4317 hsa-miR-520f hsa-miR-3194-5p hsa-miR-4254 hsa-miR-15a hsa-miR-548k hsa-miR-25 hsa-miR-30d
    SwitchGear 3'UTR luciferase reporter plasmidTMEM87A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM87A
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM87A

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for TMEM87A

    Clone
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    OriGene clones in human, mouse for TMEM87A (see all 12)
    OriGene ORF clones in mouse, rat for TMEM87A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TMEM87A (NM_001110503)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM87A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM87A

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMEM87A
    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM87A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM87A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TM87A_HUMAN, Q8NBN3: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus4
    nucleus4
    plasma membrane3
    endoplasmic reticulum1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TMEM87A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM87A
    Interactions:

        Search GeneGlobe Interaction Network for TMEM87A

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for TMEM87A (Q8NBN33 ENSP000003744844) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MDM2Q009873I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    VCPENSP000003517774STRING: ENSP00000351777
    PIGSENSP000003094304STRING: ENSP00000309430
    VPS4BENSP000002384974STRING: ENSP00000238497
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM87A (TM87A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TMEM87A gene (3 alternative transcripts): 
    NM_001110503.2  NM_001286487.1  NM_015497.4  

    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000389834(uc021sjr.1 uc001zpf.4) ENST00000568067 ENST00000564329
    ENST00000566014 ENST00000562946 ENST00000569075(uc010bcu.1) ENST00000568400
    ENST00000563371 ENST00000561578 ENST00000566474 ENST00000307216(uc001zpg.2)
    ENST00000568432 ENST00000448392
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM87A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM87A (see all 41):
    hsa-miR-4317 hsa-miR-520f hsa-miR-3194-5p hsa-miR-4254 hsa-miR-15a hsa-miR-548k hsa-miR-25 hsa-miR-30d
    SwitchGear 3'UTR luciferase reporter plasmidTMEM87A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM87A
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM87A
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM87A (see all 12)
    OriGene ORF clones in mouse, rat for TMEM87A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TMEM87A (NM_001110503)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM87A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM87A
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM87A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM87A
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM87A
      QuantiFast Probe-based Assays in human, mouse, rat TMEM87A

    Selected AceView cDNA sequences (see all 414):

    BQ225871 AI924509 AI393050 AU280715 BI495512 AW151678 BG057162 BM830189 
    CB134628 BQ878921 AA928582 BM927105 CF272363 BF793113 BQ003043 AA781809 
    CA502979 T98083 CR596160 CK821593 AI073483 AI582939 BU620168 BM977760 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM87A    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20
    SP1:                                            -                                                                                 
    SP2:              -                             -                                                                                 
    SP3:                                                                                                                              


    ECgene alternative splicing isoforms for TMEM87A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMEM87A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCACTTTTTA
    TMEM87A Expression
    About this image


    TMEM87A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 11) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    TMEM87A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM87A Protein Expression
        Custom PCR Arrays for TMEM87A
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM87A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM87A
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    QuantiFast Probe-based Assays in human, mouse, rat TMEM87A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM87A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TMEM87A gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem87a1 , 5 transmembrane protein 87A1, 5 89.23(n)1
    92.78(a)1
      2 (60.31 cM)5
    2114991  NM_001110497.11  NP_001103967.11 
     1203553125 
    chicken
    (Gallus gallus)
    Aves TMEM87A1 transmembrane protein 87A 75.84(n)
    80.11(a)
      423231  XM_421155.4  XP_421155.2 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM87A6
    transmembrane protein 87A
    73(a)
    1 ↔ 1
    1(40009097-40037802)
    African clawed frog
    (Xenopus laevis)
    Amphibia CD362558.12   -- 75.31(n)    CD362558.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BG303486.12   -- 73.66(n)   323925  BG303486.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG176606
    --
    39(a)
    1 → many
    2L(1707132-1710421)
    worm
    (Caenorhabditis elegans)
    Secernentea C52B9.46
    Protein C52B9.4 (C52B9.4) mRNA, complete cds
    31(a)
    1 → many
    X(4260652-4264605) WBGene00016867
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PTM16
    --
    Protein of unknown function, copurifies with late ...
    Putative protein of unknown function; green fluore...
    17(a)
    14(a)
    many ↔ many
    many ↔ many
    XI(362622-364193) YKL039W
    VIII(70276-71874) YHL017W


    ENSEMBL Gene Tree for TMEM87A (if available)
    TreeFam Gene Tree for TMEM87A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TMEM87A gene
    TMEM87B2  
    1 SIMAP similar gene for TMEM87A using alignment to 8 protein entries:     TM87A_HUMAN (see all proteins):
    TMEM87B

    Find genes that share paralogs with TMEM87A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TMEM87A (see all 1266)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs6593541,2
    C,F,A,H--42502519(+) TTTTTA/TAAAAT 1 -- int18Minor allele frequency- T:0.14NS EA NA CSA WA 658
    rs1817095041,2
    --42502579(+) CTGCAA/GTATGA 1 -- int10--------
    rs37430121,2
    H--42502807(-) TTTTAT/CCCAAT 1 -- ut314Minor allele frequency- C:0.00NS EA 406
    rs1469476921,2
    --42502808(+) TTGGAA/TAAAAC 1 -- ut310--------
    rs81081,2
    C,F,H--42502896(+) ACCAGA/TTACCA 1 -- ut31 ese326Minor allele frequency- T:0.13MN NA NS EA CSA WA 2868
    rs1843424111,2
    --42502913(+) TCCATC/TCTAAA 1 -- ut310--------
    rs734074191,2
    C,F--42502916(+) ATCCTG/AAAGAA 1 -- ut311Minor allele frequency- A:0.50WA 2
    rs1434176871,2
    --42502946(+) TCCACA/GCTACT 1 -- ut310--------
    rs1887698241,2
    --42503040(+) AGCACA/GGTGCT 1 -- ut310--------
    rs1819136331,2
    --42503090(+) ACAAAA/GCATTG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TMEM87A (42502726 - 42565861 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for TMEM87A:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1006302CNV Deletion20482838
    nsv827310CNV Loss20364138
    nsv832985CNV Loss17160897
    nsv904133CNV Gain21882294
    nsv827308CNV Gain20364138
    nsv471683CNV Gain+Loss15918152

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM87A
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM87A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for TMEM87A:    
    About MalaCards
    congenital dyserythropoietic anemia type i


    Find genes that share disorders with TMEM87A           About GenesLikeMe

    Genetic Association Database (GAD): TMEM87A

    Export disorders for TMEM87A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMEM87A gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with TMEM87A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (DNA Res. 2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    6. A data set of human endogenous protein ubiquitination sites. (PubMed id 20972266)1 Shi Y....Qin J. (amp 2011)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    9. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    10. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 25963 HGNC: 24522 AceView: DKFZP564G2022 Ensembl:ENSG00000103978 euGenes: HUgn25963
    ECgene: TMEM87A H-InvDB: TMEM87A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TMEM87A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TMEM87A gene:
    Search GeneIP for patents involving TMEM87A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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