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Aliases for TMEM82 Gene

Aliases for TMEM82 Gene

  • Transmembrane Protein 82 2 3 5

External Ids for TMEM82 Gene

Previous GeneCards Identifiers for TMEM82 Gene

  • GC01P015942
  • GC01P016068
  • GC01P014587

Summaries for TMEM82 Gene

GeneCards Summary for TMEM82 Gene

TMEM82 (Transmembrane Protein 82) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM82 Gene

Genomics for TMEM82 Gene

Regulatory Elements for TMEM82 Gene

Enhancers for TMEM82 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G015749 1.4 Ensembl ENCODE dbSUPER 10.4 +7.3 7272 1.1 ELF3 ATF1 PKNOX1 SIN3A DMAP1 GATA2 FOS CREM DEK ZBTB2 SLC25A34 TMEM82 ENSG00000224459
GH01G015702 1.7 FANTOM5 Ensembl ENCODE dbSUPER 6.3 -38.5 -38535 2.6 PTBP1 FOXA2 CBX3 NFIB ZNF195 RAD21 ZNF121 EGR1 ZNF366 FOS SLC25A34 PLEKHM2 TMEM82 FAM131C PIR54516 PIR59281
GH01G015678 1.9 FANTOM5 Ensembl ENCODE dbSUPER 5.3 -60.1 -60065 8.0 HDGF PKNOX1 ARNT SIN3A ARID4B YBX1 ZNF2 ZNF766 ZNF143 ZNF207 SPEN PLEKHM2 ENSG00000237938 ZBTB17 RPL22P3 CASP9 SLC25A34 LINC01772 RPS16P1 CROCCP2
GH01G015605 0.8 ENCODE 6 -136.3 -136333 1.2 FOXA2 ARID4B ZBTB40 RARA KAT2B CREM MIXL1 THAP11 CEBPB PPARG SLC25A34 AGMAT TMEM82 RNU7-179P PIR54927 GC01P015607
GH01G015592 0.8 dbSUPER 5.9 -149.3 -149344 1.8 PKNOX1 SIN3A BACH1 ARID3A EED ETV6 FOS RELB IKZF2 CREM PLEKHM2 ENSG00000251866 AGMAT FBLIM1 RSC1A1 SLC25A34 CASP9 TMEM82 PIR41201
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TMEM82 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the TMEM82 gene promoter:

Genomic Location for TMEM82 Gene

Chromosome:
1
Start:
15,742,422 bp from pter
End:
15,747,982 bp from pter
Size:
5,561 bases
Orientation:
Plus strand

Genomic View for TMEM82 Gene

Genes around TMEM82 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM82 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM82 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM82 Gene

Proteins for TMEM82 Gene

  • Protein details for TMEM82 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0PJX8-TMM82_HUMAN
    Recommended name:
    Transmembrane protein 82
    Protein Accession:
    A0PJX8
    Secondary Accessions:
    • B2RP27
    • Q5VVD4

    Protein attributes for TMEM82 Gene

    Size:
    343 amino acids
    Molecular mass:
    37222 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM82 Gene

Post-translational modifications for TMEM82 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM82 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM82 Gene

Domains & Families for TMEM82 Gene

Protein Domains for TMEM82 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM82 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A0PJX8

UniProtKB/Swiss-Prot:

TMM82_HUMAN :
  • Belongs to the TMEM82 family.
Family:
  • Belongs to the TMEM82 family.
genes like me logo Genes that share domains with TMEM82: view

No data available for Gene Families for TMEM82 Gene

Function for TMEM82 Gene

genes like me logo Genes that share phenotypes with TMEM82: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM82 Gene

Localization for TMEM82 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM82 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TMEM82 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for TMEM82 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM82: view

Pathways & Interactions for TMEM82 Gene

SuperPathways for TMEM82 Gene

No Data Available

Interacting Proteins for TMEM82 Gene

Gene Ontology (GO) - Biological Process for TMEM82 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM82 Gene

Transcripts for TMEM82 Gene

mRNA/cDNA for TMEM82 Gene

Unigene Clusters for TMEM82 Gene

Transmembrane protein 82:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM82 Gene

No ASD Table

Relevant External Links for TMEM82 Gene

GeneLoc Exon Structure for
TMEM82
ECgene alternative splicing isoforms for
TMEM82

Expression for TMEM82 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TMEM82 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM82 Gene

This gene is overexpressed in Liver (x26.8), Kidney - Cortex (x10.4), Small Intestine - Terminal Ileum (x7.3), and Colon - Transverse (x6.4).

Protein differential expression in normal tissues from HIPED for TMEM82 Gene

This gene is overexpressed in Gallbladder (52.3), Liver (9.7), and Kidney (7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TMEM82 Gene



Protein tissue co-expression partners for TMEM82 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TMEM82 Gene:

TMEM82

SOURCE GeneReport for Unigene cluster for TMEM82 Gene:

Hs.454828
genes like me logo Genes that share expression patterns with TMEM82: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM82 Gene

Orthologs for TMEM82 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM82 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM82 34 35
  • 99.09 (n)
cow
(Bos Taurus)
Mammalia TMEM82 34 35
  • 86.43 (n)
dog
(Canis familiaris)
Mammalia TMEM82 34 35
  • 84.65 (n)
mouse
(Mus musculus)
Mammalia Tmem82 34 16 35
  • 80.6 (n)
oppossum
(Monodelphis domestica)
Mammalia TMEM82 35
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM82 35
  • 69 (a)
OneToOne
chicken
(Gallus gallus)
Aves TMEM82 34 35
  • 66.77 (n)
lizard
(Anolis carolinensis)
Reptilia TMEM82 35
  • 52 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem82 34
  • 66.46 (n)
Str.4345 34
zebrafish
(Danio rerio)
Actinopterygii LOC568809 34
  • 52.63 (n)
TMEM82 35
  • 43 (a)
OneToOne
Species where no ortholog for TMEM82 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM82 Gene

ENSEMBL:
Gene Tree for TMEM82 (if available)
TreeFam:
Gene Tree for TMEM82 (if available)

Paralogs for TMEM82 Gene

No data available for Paralogs for TMEM82 Gene

Variants for TMEM82 Gene

Sequence variations from dbSNP and Humsavar for TMEM82 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000512368 -- 15,742,729(+) CTGGT(C/T)TCCCG intron-variant
rs1000915865 -- 15,740,775(+) ACCTC(C/T)ACCTC upstream-variant-2KB, utr-variant-3-prime
rs1002016956 -- 15,742,473(+) CTCTC(A/C)TTCCC upstream-variant-2KB
rs1002573247 -- 15,745,618(+) CCGGG(C/T)ATAGT intron-variant
rs1002757512 -- 15,741,075(+) GAAGC(G/T)CCGGG upstream-variant-2KB, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for TMEM82 Gene

Variant ID Type Subtype PubMed ID
dgv11n27 CNV gain 19166990
dgv151n54 CNV gain 21841781
esv3585317 CNV gain 21293372
esv3585319 CNV gain 21293372
nsv508925 CNV insertion 20534489
nsv524044 CNV loss 19592680
nsv545617 CNV loss 21841781
nsv954825 CNV deletion 24416366

Variation tolerance for TMEM82 Gene

Residual Variation Intolerance Score: 89.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.70; 78.63% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM82 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM82

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM82 Gene

Disorders for TMEM82 Gene

Relevant External Links for TMEM82

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMEM82

No disorders were found for TMEM82 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM82 Gene

Publications for TMEM82 Gene

  1. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3 64
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for TMEM82 Gene

Sources for TMEM82 Gene

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