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Aliases for TMEM82 Gene

Aliases for TMEM82 Gene

  • Transmembrane Protein 82 2 3 5

External Ids for TMEM82 Gene

Previous GeneCards Identifiers for TMEM82 Gene

  • GC01P015942
  • GC01P016068
  • GC01P014587

Summaries for TMEM82 Gene

GeneCards Summary for TMEM82 Gene

TMEM82 (Transmembrane Protein 82) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM82 Gene

Genomics for TMEM82 Gene

Regulatory Elements for TMEM82 Gene

Enhancers for TMEM82 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TMEM82 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the TMEM82 gene promoter:

Genomic Location for TMEM82 Gene

Chromosome:
1
Start:
15,742,422 bp from pter
End:
15,747,982 bp from pter
Size:
5,561 bases
Orientation:
Plus strand

Genomic View for TMEM82 Gene

Genes around TMEM82 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM82 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM82 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM82 Gene

Proteins for TMEM82 Gene

  • Protein details for TMEM82 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0PJX8-TMM82_HUMAN
    Recommended name:
    Transmembrane protein 82
    Protein Accession:
    A0PJX8
    Secondary Accessions:
    • B2RP27
    • Q5VVD4

    Protein attributes for TMEM82 Gene

    Size:
    343 amino acids
    Molecular mass:
    37222 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM82 Gene

Proteomics data for TMEM82 Gene at MOPED

Post-translational modifications for TMEM82 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM82 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM82 Gene

Domains & Families for TMEM82 Gene

Protein Domains for TMEM82 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM82 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A0PJX8

UniProtKB/Swiss-Prot:

TMM82_HUMAN :
  • Belongs to the TMEM82 family.
Family:
  • Belongs to the TMEM82 family.
genes like me logo Genes that share domains with TMEM82: view

No data available for Gene Families for TMEM82 Gene

Function for TMEM82 Gene

genes like me logo Genes that share phenotypes with TMEM82: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM82 Gene

Localization for TMEM82 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM82 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM82 Gene COMPARTMENTS Subcellular localization image for TMEM82 gene
Compartment Confidence
plasma membrane 3

No data available for Gene Ontology (GO) - Cellular Components for TMEM82 Gene

Pathways & Interactions for TMEM82 Gene

SuperPathways for TMEM82 Gene

No Data Available

Interacting Proteins for TMEM82 Gene

Gene Ontology (GO) - Biological Process for TMEM82 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM82 Gene

Drugs & Compounds for TMEM82 Gene

No Compound Related Data Available

Transcripts for TMEM82 Gene

mRNA/cDNA for TMEM82 Gene

Unigene Clusters for TMEM82 Gene

Transmembrane protein 82:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM82 Gene

No ASD Table

Relevant External Links for TMEM82 Gene

GeneLoc Exon Structure for
TMEM82
ECgene alternative splicing isoforms for
TMEM82

Expression for TMEM82 Gene

mRNA expression in normal human tissues for TMEM82 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM82 Gene

This gene is overexpressed in Liver (x26.8), Kidney - Cortex (x10.4), Small Intestine - Terminal Ileum (x7.3), and Colon - Transverse (x6.4).

Protein differential expression in normal tissues from HIPED for TMEM82 Gene

This gene is overexpressed in Gallbladder (52.3), Liver (9.7), and Kidney (7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TMEM82 Gene



SOURCE GeneReport for Unigene cluster for TMEM82 Gene Hs.454828

genes like me logo Genes that share expression patterns with TMEM82: view

Protein tissue co-expression partners for TMEM82 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TMEM82 Gene

Orthologs for TMEM82 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM82 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TMEM82 35
  • 86.43 (n)
  • 81.74 (a)
TMEM82 36
  • 74 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM82 35
  • 84.65 (n)
  • 80.65 (a)
TMEM82 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem82 35
  • 80.6 (n)
  • 80.12 (a)
Tmem82 16
Tmem82 36
  • 76 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TMEM82 35
  • 99.09 (n)
  • 98.98 (a)
TMEM82 36
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM82 36
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM82 36
  • 69 (a)
OneToOne
chicken
(Gallus gallus)
Aves TMEM82 35
  • 66.77 (n)
  • 63.29 (a)
TMEM82 36
  • 60 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM82 36
  • 52 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.4345 35
tmem82 35
  • 66.46 (n)
  • 59.37 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC568809 35
  • 52.63 (n)
  • 50 (a)
TMEM82 36
  • 43 (a)
OneToOne
Species with no ortholog for TMEM82:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM82 Gene

ENSEMBL:
Gene Tree for TMEM82 (if available)
TreeFam:
Gene Tree for TMEM82 (if available)

Paralogs for TMEM82 Gene

No data available for Paralogs for TMEM82 Gene

Variants for TMEM82 Gene

Sequence variations from dbSNP and Humsavar for TMEM82 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs11580250 - 15,746,960(+) GGGTC(A/G/T)CTGGC reference, missense
rs1969241 -- 15,746,242(+) acttt(C/G)ggagg intron-variant
rs7511651 -- 15,744,376(+) GCCAG(C/T)GCTAC reference, missense
rs7533907 -- 15,744,654(+) GCCGA(C/G)AGCCA intron-variant
rs7525747 -- 15,744,417(+) GCACA(C/T)GGCCT reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for TMEM82 Gene

Variant ID Type Subtype PubMed ID
dgv171n71 CNV Gain 21882294
nsv524044 CNV Loss 19592680
dgv11n27 CNV Gain 19166990
dgv172n71 CNV Gain 21882294
nsv508925 CNV Insertion 20534489
dgv173n71 CNV Loss 21882294
nsv871462 CNV Gain+Loss 21882294
nsv871550 CNV Loss 21882294
nsv870503 CNV Loss 21882294

Variation tolerance for TMEM82 Gene

Residual Variation Intolerance Score: 89.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.70; 78.63% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for TMEM82 Gene

Disorders for TMEM82 Gene

Relevant External Links for TMEM82

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMEM82

No disorders were found for TMEM82 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM82 Gene

Publications for TMEM82 Gene

  1. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TMEM82 Gene

Sources for TMEM82 Gene

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