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Aliases for TMEM80 Gene

Aliases for TMEM80 Gene

  • Transmembrane Protein 80 2 3

External Ids for TMEM80 Gene

Previous GeneCards Identifiers for TMEM80 Gene

  • GC11P000512

Summaries for TMEM80 Gene

GeneCards Summary for TMEM80 Gene

TMEM80 (Transmembrane Protein 80) is a Protein Coding gene. An important paralog of this gene is TMEM216.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM80 Gene

Genomics for TMEM80 Gene

Regulatory Elements for TMEM80 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMEM80 Gene

695,428 bp from pter
705,028 bp from pter
9,601 bases
Plus strand

Genomic View for TMEM80 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM80 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM80 Gene

Proteins for TMEM80 Gene

  • Protein details for TMEM80 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 80
    Protein Accession:
    Secondary Accessions:
    • A8MQ01
    • A8MXY8
    • B7WNU5

    Protein attributes for TMEM80 Gene

    168 amino acids
    Molecular mass:
    18160 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM80 Gene


neXtProt entry for TMEM80 Gene

Proteomics data for TMEM80 Gene at MOPED

Post-translational modifications for TMEM80 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM80 Gene

No data available for DME Specific Peptides for TMEM80 Gene

Domains & Families for TMEM80 Gene

Protein Domains for TMEM80 Gene


Suggested Antigen Peptide Sequences for TMEM80 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM80: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM80 Gene

Function for TMEM80 Gene

Phenotypes for TMEM80 Gene

GenomeRNAi human phenotypes for TMEM80:
genes like me logo Genes that share phenotypes with TMEM80: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM80

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM80 Gene

Localization for TMEM80 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM80 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM80 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM80: view

No data available for Subcellular locations from COMPARTMENTS for TMEM80 Gene

Pathways & Interactions for TMEM80 Gene

SuperPathways for TMEM80 Gene

No Data Available

Interacting Proteins for TMEM80 Gene

Gene Ontology (GO) - Biological Process for TMEM80 Gene


No data available for Pathways by source and SIGNOR curated interactions for TMEM80 Gene

Drugs & Compounds for TMEM80 Gene

No Compound Related Data Available

Transcripts for TMEM80 Gene

Unigene Clusters for TMEM80 Gene

Transmembrane protein 80:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM80

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM80 Gene

No ASD Table

Relevant External Links for TMEM80 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM80 Gene

mRNA expression in normal human tissues for TMEM80 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for TMEM80 Gene

This gene is overexpressed in Liver, secretome (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TMEM80 Gene

SOURCE GeneReport for Unigene cluster for TMEM80 Gene Hs.448664

genes like me logo Genes that share expression patterns with TMEM80: view

Protein tissue co-expression partners for TMEM80 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TMEM80 Gene

Orthologs for TMEM80 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM80 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TMEM80 35
  • 83.22 (n)
  • 81.12 (a)
TMEM80 36
  • 80 (a)
(Canis familiaris)
Mammalia TMEM80 35
  • 78.32 (n)
  • 76.92 (a)
TMEM80 36
  • 75 (a)
(Mus musculus)
Mammalia Tmem80 35
  • 74.86 (n)
  • 72.95 (a)
Tmem80 16
Tmem80 36
  • 73 (a)
(Pan troglodytes)
Mammalia TMEM80 35
  • 98.94 (n)
  • 97.88 (a)
TMEM80 36
  • 66 (a)
(Gallus gallus)
Aves TMEM80 35
  • 61.47 (n)
  • 63.83 (a)
TMEM80 36
  • 60 (a)
(Anolis carolinensis)
Reptilia TMEM80 36
  • 61 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem80 35
  • 60.95 (n)
  • 62.14 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 37 (a)
Species with no ortholog for TMEM80:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM80 Gene

Gene Tree for TMEM80 (if available)
Gene Tree for TMEM80 (if available)

Paralogs for TMEM80 Gene

Paralogs for TMEM80 Gene

(1) SIMAP similar genes for TMEM80 Gene using alignment to 3 proteins: Pseudogenes for TMEM80 Gene

genes like me logo Genes that share paralogs with TMEM80: view

Variants for TMEM80 Gene

Structural Variations from Database of Genomic Variants (DGV) for TMEM80 Gene

Variant ID Type Subtype PubMed ID
dgv182e199 CNV Deletion 23128226
dgv921n71 CNV Loss 21882294
dgv922n71 CNV Loss 21882294
nsv469923 CNV Loss 18288195
essv23843 CNV CNV 17122850
nsv896545 CNV Loss 21882294
dgv936n71 CNV Loss 21882294
nsv896570 CNV Loss 21882294
nsv832043 CNV Loss 17160897
nsv896573 CNV Loss 21882294
dgv943n71 CNV Loss 21882294
dgv944n71 CNV Loss 21882294
nsv896578 CNV Loss 21882294
nsv896579 CNV Loss 21882294
esv1638671 CNV Insertion 17803354
nsv522733 CNV Loss 19592680

Relevant External Links for TMEM80 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for TMEM80 Gene

Disorders for TMEM80 Gene

Relevant External Links for TMEM80

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with TMEM80: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM80 Gene

Publications for TMEM80 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 67

Products for TMEM80 Gene

Sources for TMEM80 Gene

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