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Aliases for TMEM75 Gene

Subcategory (RNA class) for TMEM75 Gene

lncRNA

Quality Score for this RNA gene is

3

Aliases for TMEM75 Gene

  • Transmembrane Protein 75 2 3 5

External Ids for TMEM75 Gene

ORGUL Members for TMEM75 Gene

Previous GeneCards Identifiers for TMEM75 Gene

  • GC08U900607
  • GC08M129027
  • GC08M129030
  • GC08M128958

Summaries for TMEM75 Gene

GeneCards Summary for TMEM75 Gene

TMEM75 (Transmembrane Protein 75) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for TMEM75 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM75 Gene

Genomics for TMEM75 Gene

GeneHancer (GH) Regulatory Elements for TMEM75 Gene

Promoters and enhancers for TMEM75 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I127947 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 550.8 -1.9 -1910 5.5 PKNOX1 ATF1 NFIB ZSCAN4 NEUROD1 SIN3A FEZF1 FOS CREM SMARCA5 TMEM75 RNU1-106P RNU4-25P MIR1204 PVT1 MIR1205
GH08I127732 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 9.1 +210.6 210621 11.6 ZFP64 IRF4 YY1 E2F8 ZNF143 ZNF263 SP3 NFYC SSRP1 ZNF610 GC08P127736 GC08P127737 MYC SRRM1P1 RNU1-106P MIR1204 PVT1 TMEM75 CASC11 GC08P127740
GH08I127915 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 11.5 +30.1 30097 5.9 HDGF FOXA2 ELK1 ZNF143 FOS RUNX3 REST ZNF592 SREBF1 NFIL3 MIR1205 TMEM75 RNU1-106P PVT1 MIR1204 RNU4-25P ENSG00000278324
GH08I127972 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 12 -29.0 -29039 9.5 HDAC1 PKNOX1 ZFP64 TCF12 ZNF766 ZNF143 ETV6 ATF7 RCOR1 RUNX3 PVT1 RNU1-106P TMEM75 RNU4-25P MIR1207 MIR1204 CASC11 MYC GC08P127985 MIR1205
GH08I128032 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 9.9 -85.7 -85690 3.5 HDGF PKNOX1 ATF1 FOXA2 NEUROD1 SIN3A ZBTB7B ELK1 E2F8 FOS SRRM1P1 RNU4-25P RNU1-106P TMEM75 MIR1208 MIR1207 PVT1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TMEM75 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TMEM75 Gene

Genomic Locations for TMEM75 Gene
chr8:127,946,559-127,948,723
(GRCh38/hg38)
Size:
2,165 bases
Orientation:
Minus strand
chr8:128,958,805-128,960,969
(GRCh37/hg19)

Genomic View for TMEM75 Gene

Genes around TMEM75 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM75 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM75 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM75 Gene

Proteins for TMEM75 Gene

  • Protein details for TMEM75 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N9X5-TMM75_HUMAN
    Recommended name:
    Transmembrane protein 75
    Protein Accession:
    Q8N9X5
    Secondary Accessions:
    • B2RPD6
    • B9EH93

    Protein attributes for TMEM75 Gene

    Size:
    138 amino acids
    Molecular mass:
    15361 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM75 Gene

Post-translational modifications for TMEM75 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TMEM75 Gene

Domains & Families for TMEM75 Gene

Protein Domains for TMEM75 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TMEM75 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM75: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM75 Gene

Function for TMEM75 Gene

Phenotypes From GWAS Catalog for TMEM75 Gene

Phenotypes for TMEM75 Gene

GenomeRNAi human phenotypes for TMEM75:
genes like me logo Genes that share phenotypes with TMEM75: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM75 Gene

Localization for TMEM75 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM75 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM75 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM75: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for TMEM75 Gene

Pathways & Interactions for TMEM75 Gene

SuperPathways for TMEM75 Gene

No Data Available

Interacting Proteins for TMEM75 Gene

Gene Ontology (GO) - Biological Process for TMEM75 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM75 Gene

Drugs & Compounds for TMEM75 Gene

No Compound Related Data Available

Transcripts for TMEM75 Gene

mRNA/cDNA for TMEM75 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM75 Gene

Transmembrane protein 75:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM75 Gene

No ASD Table

Relevant External Links for TMEM75 Gene

GeneLoc Exon Structure for
TMEM75
ECgene alternative splicing isoforms for
TMEM75

Expression for TMEM75 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TMEM75 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM75 Gene

This gene is overexpressed in Testis (x22.3).

Protein differential expression in normal tissues from HIPED for TMEM75 Gene

This gene is overexpressed in Neutrophil (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TMEM75 Gene



Protein tissue co-expression partners for TMEM75 Gene

NURSA nuclear receptor signaling pathways regulating expression of TMEM75 Gene:

TMEM75

SOURCE GeneReport for Unigene cluster for TMEM75 Gene:

Hs.629674
genes like me logo Genes that share expression patterns with TMEM75: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM75 Gene

Orthologs for TMEM75 Gene

Evolution for TMEM75 Gene

ENSEMBL:
Gene Tree for TMEM75 (if available)
TreeFam:
Gene Tree for TMEM75 (if available)

No data available for Orthologs for TMEM75 Gene

Paralogs for TMEM75 Gene

No data available for Paralogs for TMEM75 Gene

Variants for TMEM75 Gene

Sequence variations from dbSNP and Humsavar for TMEM75 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1000449436 -- 127,947,415(-) G/A non_coding_transcript_variant
rs1000799558 -- 127,948,307(-) G/A non_coding_transcript_variant
rs1001453082 -- 127,948,143(-) G/A non_coding_transcript_variant
rs1002455881 -- 127,949,194(-) C/T upstream_transcript_variant
rs1003268300 -- 127,950,022(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM75 Gene

Variant ID Type Subtype PubMed ID
esv3618786 CNV loss 21293372
nsv499795 OTHER inversion 21111241
nsv524801 CNV loss 19592680
nsv7419 OTHER inversion 18451855

Variation tolerance for TMEM75 Gene

Gene Damage Index Score: 0.57; 12.25% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TMEM75 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM75

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM75 Gene

Disorders for TMEM75 Gene

Additional Disease Information for TMEM75

No disorders were found for TMEM75 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM75 Gene

Publications for TMEM75 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. (PMID: 24509480) DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium … Morris AP (Nature genetics 2014) 3 58
  3. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie AG … Butte NF (PloS one 2012) 3 58
  4. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 4 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for TMEM75 Gene

Sources for TMEM75 Gene

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