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Aliases for TMEM75 Gene

Subcategory (RNA class) for TMEM75 Gene

lncRNA

Quality Score for this RNA gene is

3

Aliases for TMEM75 Gene

  • Transmembrane Protein 75 2 3 5

External Ids for TMEM75 Gene

ORGUL Members for TMEM75 Gene

Previous GeneCards Identifiers for TMEM75 Gene

  • GC08U900607
  • GC08M129027
  • GC08M129030
  • GC08M128958

Summaries for TMEM75 Gene

GeneCards Summary for TMEM75 Gene

TMEM75 (Transmembrane Protein 75) is an RNA Gene, and is affiliated with the lncRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM75 Gene

Genomics for TMEM75 Gene

Regulatory Elements for TMEM75 Gene

Enhancers for TMEM75 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F127972 1.5 FANTOM5 Ensembl ENCODE 12 -29.0 -29039 9.5 HDAC1 PKNOX1 CBX3 TBL1XR1 ZFP64 GATA2 ZNF143 ETV6 SMARCA5 CEBPB PVT1 RNU1-106P TMEM75 RNU4-25P MIR1207 MIR1204 CASC11 MYC GC08P127985 MIR1205
GH08F127915 1.5 FANTOM5 Ensembl ENCODE 11.5 +30.0 30023 7.0 HDAC1 CBX3 TBL1XR1 NFXL1 RAD21 EGR1 FOS SMARCA5 CEBPB REST SRRM1P1 MIR1205 TMEM75 RNU1-106P MIR1204 PVT1 RNU4-25P ENSG00000278324
GH08F127863 1.6 FANTOM5 Ensembl ENCODE 10.5 +80.4 80392 10.2 HDGF PKNOX1 ATF1 ZFP64 SIN3A YBX1 ETS1 YY1 ELK1 ZNF207 SRRM1P1 RNU1-106P MIR1204 PVT1 CASC11 MYC TMEM75 RNU4-25P ENSG00000278324 GC08P127796
GH08F128181 1.7 FANTOM5 Ensembl ENCODE 9.8 -235.3 -235313 5.1 HDGF ATF1 MLX ZFP64 ARID4B YBX1 DMAP1 ZNF48 SLC30A9 FOS MIR1208 MIR1207 CASC11 MYC RNU1-106P TMEM75 RNU4-25P GC08P128172 GC08P128221
GH08F128032 1.6 FANTOM5 Ensembl ENCODE 9.9 -85.7 -85710 3.5 PKNOX1 SIN3A ELK1 FOS REST ZNF592 SREBF1 MBD2 MEF2D SMARCA4 RNU4-25P RNU1-106P TMEM75 MIR1208 MIR1207
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TMEM75 on UCSC Golden Path with GeneCards custom track

Genomic Location for TMEM75 Gene

Chromosome:
8
Start:
127,946,559 bp from pter
End:
127,948,723 bp from pter
Size:
2,165 bases
Orientation:
Minus strand

Genomic View for TMEM75 Gene

Genes around TMEM75 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM75 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM75 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM75 Gene

Proteins for TMEM75 Gene

  • Protein details for TMEM75 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N9X5-TMM75_HUMAN
    Recommended name:
    Transmembrane protein 75
    Protein Accession:
    Q8N9X5
    Secondary Accessions:
    • B2RPD6
    • B9EH93

    Protein attributes for TMEM75 Gene

    Size:
    138 amino acids
    Molecular mass:
    15361 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM75 Gene

Post-translational modifications for TMEM75 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TMEM75 Gene

Domains & Families for TMEM75 Gene

Protein Domains for TMEM75 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TMEM75 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM75: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM75 Gene

Function for TMEM75 Gene

Phenotypes for TMEM75 Gene

GenomeRNAi human phenotypes for TMEM75:
genes like me logo Genes that share phenotypes with TMEM75: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM75 Gene

Localization for TMEM75 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM75 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM75 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM75: view

No data available for Subcellular locations from COMPARTMENTS for TMEM75 Gene

Pathways & Interactions for TMEM75 Gene

SuperPathways for TMEM75 Gene

No Data Available

Interacting Proteins for TMEM75 Gene

Gene Ontology (GO) - Biological Process for TMEM75 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM75 Gene

Transcripts for TMEM75 Gene

mRNA/cDNA for TMEM75 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM75 Gene

Transmembrane protein 75:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM75 Gene

No ASD Table

Relevant External Links for TMEM75 Gene

GeneLoc Exon Structure for
TMEM75
ECgene alternative splicing isoforms for
TMEM75

Expression for TMEM75 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TMEM75 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM75 Gene

This gene is overexpressed in Testis (x22.3).

Protein differential expression in normal tissues from HIPED for TMEM75 Gene

This gene is overexpressed in Neutrophil (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TMEM75 Gene



Protein tissue co-expression partners for TMEM75 Gene

NURSA nuclear receptor signaling pathways regulating expression of TMEM75 Gene:

TMEM75

SOURCE GeneReport for Unigene cluster for TMEM75 Gene:

Hs.629674
genes like me logo Genes that share expression patterns with TMEM75: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TMEM75 Gene

Orthologs for TMEM75 Gene

Evolution for TMEM75 Gene

ENSEMBL:
Gene Tree for TMEM75 (if available)
TreeFam:
Gene Tree for TMEM75 (if available)

No data available for Orthologs for TMEM75 Gene

Paralogs for TMEM75 Gene

No data available for Paralogs for TMEM75 Gene

Variants for TMEM75 Gene

Sequence variations from dbSNP and Humsavar for TMEM75 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs111599694 -- 127,946,528(+) CACGG(A/G)TGAAT intron-variant, downstream-variant-500B
rs111775139 -- 127,950,406(+) CATGT(A/G)GGGAG intron-variant, upstream-variant-2KB
rs112305873 -- 127,946,863(+) GGTCA(C/T)GACTC intron-variant, nc-transcript-variant
rs112962151 -- 127,950,370(+) CTGCC(C/T)GTCCA intron-variant, upstream-variant-2KB
rs113559770 -- 127,948,855(+) TGTAG(C/T)AGCCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TMEM75 Gene

Variant ID Type Subtype PubMed ID
nsv7419 OTHER inversion 18451855
nsv524801 CNV loss 19592680
nsv499795 OTHER inversion 21111241
esv3618786 CNV loss 21293372

Variation tolerance for TMEM75 Gene

Gene Damage Index Score: 0.57; 12.25% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM75 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM75

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM75 Gene

Disorders for TMEM75 Gene

Relevant External Links for TMEM75

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMEM75

No disorders were found for TMEM75 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM75 Gene

Publications for TMEM75 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. (PMID: 24509480) . … Morris A.P. (Nat. Genet. 2014) 3 64
  3. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3 64
  4. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C. … Lander E.S. (Nature 2006) 4 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for TMEM75 Gene

Sources for TMEM75 Gene

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