Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TMEM74 Gene

protein-coding   GIFtS: 42
GCID: GC08M109619

Transmembrane Protein 74

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Transmembrane Protein 741 2
NET362

External Ids:    HGNC: 264091   Entrez Gene: 1577532   Ensembl: ENSG000001648417   OMIM: 6139355   UniProtKB: Q96NL13   
ORGUL members:         

Export aliases for TMEM74 gene to outside databases

Previous GC identifers: GC08M109865 GC08M105116


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TMEM74 Gene:
TMEM74 (transmembrane protein 74) is a protein-coding gene. An important paralog of this gene is TMEM74B.

UniProtKB/Swiss-Prot: TMM74_HUMAN, Q96NL1
Function: Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NT_008046.17  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM74 gene promoter:
         Nkx3-1 v2   Nkx3-1   HFH-3   FOXI1   TBP   Nkx3-1 v4   Brachyury   Nkx3-1 v3   Nkx3-1 v1   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM74 promoter sequence
   Search Chromatin IP Primers for TMEM74

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM74


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q23.1   Ensembl cytogenetic band:  8q23.1   HGNC cytogenetic band: 8q23.1

TMEM74 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM74 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M109619:  view genomic region     (about GC identifiers)

Start:
109,619,079 bp from pter      End:
109,799,844 bp from pter
Size:
180,766 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TMM74_HUMAN, Q96NL1 (See protein sequence)
Recommended Name: Transmembrane protein 74  
Size: 305 amino acids; 33338 Da

Explore the universe of human proteins at neXtProt for TMEM74: NX_Q96NL1

Explore proteomics data for TMEM74 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TMEM74 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_694560.1  
    ENSEMBL proteins: 
     ENSP00000297459  

    TMEM74 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for TMEM74
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TMEM74
    GenScript Custom Purified and Recombinant Proteins Services for TMEM74
    Novus Biologicals TMEM74 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM74

     
    Search eBioscience for Proteins for TMEM74 

     
    Search antibodies-online for proteins for TMEM74 

     
    antibodies-online peptides for TMEM74

    TMEM74 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TMEM74
    Novus Biologicals TMEM74 Antibodies
    Search for Antibodies for TMEM74 at Abcam
    Cloud-Clone Corp. Antibodies for TMEM74
    Search ThermoFisher Antibodies for TMEM74
    antibodies-online antibodies for TMEM74 (16 products) 

    TMEM74 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TMEM74
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMEM74
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM74
    Cloud-Clone Corp. CLIAs for TMEM74
    Search eBioscience for ELISAs for TMEM74 
    antibodies-online kits for TMEM74 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus

    ProtoNet protein and cluster: Q96NL1

    UniProtKB/Swiss-Prot: TMM74_HUMAN, Q96NL1
    Similarity: Belongs to the TMEM74 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TMM74_HUMAN, Q96NL1
    Function: Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction

    Animal Models:

       genOway: Develop your customized and physiologically relevant rodent model for TMEM74

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM74:
    hsa-mir-122-5p (MIRT023244)

    Block miRNA regulation of human, mouse, rat TMEM74 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate TMEM74:
    hsa-miR-875-3p hsa-miR-520f hsa-miR-3126-3p hsa-miR-589 hsa-miR-580
    SwitchGear 3'UTR luciferase reporter plasmidTMEM74 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM74
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM74

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMEM74

    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM74 (see all 7)
    OriGene ORF clones in mouse, rat for TMEM74
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM74 (NM_153015)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM74
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM74

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMEM74
    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM74 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM74


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    TMM74_HUMAN, Q96NL1: Lysosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane;
    Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    lysosome5
    vacuole5
    plasma membrane3
    cytosol1
    peroxisome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000421autophagic vacuole membrane IEA--
    GO:0005765lysosomal membrane IEA--
    GO:0016021integral component of membrane IEA--
    GO:0031410cytoplasmic vesicle IEA--

    Find genes that share ontologies with TMEM74           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Pathway & Disease-focused RT2 Profiler PCR Array including TMEM74: 
              Autophagy in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for TMEM74

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006914autophagy IEA--

    Find genes that share ontologies with TMEM74           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM74 (TMM74)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TMEM74 gene: 
    NM_153015.1  

    Unigene Cluster for TMEM74:

    Transmembrane protein 74
    Hs.99439  [show with all ESTs]
    Unigene Representative Sequence: AK055230
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000518838(uc003ymx.3) ENST00000297459(uc003ymy.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM74 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate TMEM74:
    hsa-miR-875-3p hsa-miR-520f hsa-miR-3126-3p hsa-miR-589 hsa-miR-580
    SwitchGear 3'UTR luciferase reporter plasmidTMEM74 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM74
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM74
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM74 (see all 7)
    OriGene ORF clones in mouse, rat for TMEM74
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM74 (NM_153015)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM74
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM74
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM74
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM74
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM74
      QuantiFast Probe-based Assays in human, mouse, rat TMEM74

    Additional mRNA sequence: 

    AK055230.1 BC030710.2 BC033057.2 

    2 DOTS entries:

    DT.40119734  DT.99932855 

    12 AceView cDNA sequences:

    AI816528 NM_153015 AK055230 BC030710 AI220089 AA456293 BC033057 BG703752 
    BI547599 BG700300 AA456690 BX095717 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TMEM74 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAATTTTTAG
    TMEM74 Expression
    About this image

    TMEM74 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM74 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.99439

    UniProtKB/Swiss-Prot: TMM74_HUMAN, Q96NL1
    Tissue specificity: Expressed in heart, lung, and placenta

        Pathway & Disease-focused RT2 Profiler PCR Array including TMEM74: 
              Autophagy in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM74
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM74
    QuantiTect SYBR Green Assays in human, mouse, rat TMEM74
    QuantiFast Probe-based Assays in human, mouse, rat TMEM74
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM74

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for TMEM74 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem741 , 5 transmembrane protein 741, 5 81.42(n)1
    77.05(a)1
      15 (16.82 cM)5
    2394081  NM_175502.31  NP_780711.11 
     438666955 
    chicken
    (Gallus gallus)
    Aves LOC1008581011 transmembrane protein 74-like 63.73(n)
    63.05(a)
      100858101  XM_004939998.1  XP_004940055.1 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM746
    transmembrane protein 74
    77(a)
    1 ↔ 1
    4(11054005-11054748)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.55722 Transcribed sequence with weak similarity to protein refNP_060824.1 (H.sapiens) hypothetical protein FLJ11190 [Homo sapiens] less 70.11(n)    BQ525417.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003314231 transmembrane protein 74-like 56.28(n)
    54.23(a)
      100331423  XM_005158240.1  XP_005158297.1 


    ENSEMBL Gene Tree for TMEM74 (if available)
    TreeFam Gene Tree for TMEM74 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TMEM74 gene
    TMEM74B2  
    1 SIMAP similar gene for TMEM74 using alignment to 1 protein entry:     TMM74_HUMAN:
    TMEM74B

    Find genes that share paralogs with TMEM74           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TMEM74 (see all 159)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs126776171,2
    H--109794853(+) ATTCCA/TCAGTT 1 -- ds50014Minor allele frequency- T:0.00NS EA 418
    rs1854130211,2
    --109794997(+) TGATCC/GTGGTA 1 -- ds50010--------
    rs1907126151,2
    --109795064(+) CAGAGC/TTGCAA 1 -- ds50010--------
    rs1467002071,2
    C--109795197(+) CTGCTC/TTTAGA 1 -- ds50010--------
    rs770199931,2
    C,F--109795235(+) GTTCAC/AAGTTG 1 -- ds50012Minor allele frequency- A:0.10CSA WA 120
    rs1822394171,2
    --109795290(+) GATGAC/GTACAG 1 -- ds50010--------
    rs2010561661,2
    --109795336(+) TTTTA-/TTTTTT 1 -- ds50010--------
    rs733135631,2
    C--109795383(+) GGGAAG/ATGCTC 1 -- ut312Minor allele frequency- A:0.04WA 120
    rs1852635511,2
    C--109795422(+) CCTGCA/GAGGCA 1 -- ut310--------
    rs1402203131,2
    --109795485(+) ATAACA/GAGATG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TMEM74 (109619079 - 109799844 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TMEM74:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv891269CNV Gain21882294
    nsv831420CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM74
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM74

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 613935    OMIM disorders: --


    Find genes that share disorders with TMEM74           About GenesLikeMe


    Export disorders for TMEM74 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TMEM74 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TMEM74)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. TMEM74, a lysosome and autophagosome protein, regulates autophagy. (PubMed id 18294959)1, 2, 9 Yu C....Wang L. (Biochem. Biophys. Res. Commun. 2008)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    5. High-throughput functional screening for autophagy-related genes and identification of TM9SF1 as an autophagosome-inducing gene. (PubMed id 19029833)2 He P.... Ma D. (Autophagy 2009)
    6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 157753 HGNC: 26409 AceView: FLJ30668 Ensembl:ENSG00000164841 euGenes: HUgn157753
    ECgene: TMEM74 H-InvDB: TMEM74

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TMEM74 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TMEM74 gene:
    Search GeneIP for patents involving TMEM74

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMEM74  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for TMEM74  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TMEM74  
     OriGene qSTAR qPCR primer pairs in human, mouse for TMEM74   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TMEM74   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TMEM74   OriGene Custom Protein Services for TMEM74  

     
     
     Block miRNA regulation of human, mouse, rat TMEM74 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TMEM74
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM74 Predesigned siRNA for gene silencing in human, mouse, rat TMEM74
     QuantiFast Probe-based Assays in human, mouse, rat TMEM74 QuantiTect SYBR Green Assays in human, mouse, rat TMEM74
     PCR Arrays including human, mouse, rat TMEM74 Search Chromatin IP Primers for TMEM74
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM74  Search GeneGlobe Interaction Network for TMEM74
     Regulatory tfbs in TMEM74 promoter
     GenScript Custom Purified and Recombinant Proteins Services for TMEM74 GenScript cDNA clones with any tag delivered in your preferred vector for TMEM74
     GenScript Custom Assay Services for TMEM74 GenScript Custom overexpressing Cell Line Services for TMEM74
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TMEM74 (TMM74)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TMEM74 antibodies
     TMEM74 lysates
     Search for Antibodies for TMEM74 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for TMEM74
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TMEM74
     Antibodies for TMEM74
     ELISAs for TMEM74
     CLIAs for TMEM74



     Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM74
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM74
     SwitchGear 3'UTR luciferase reporter plasmids for TMEM74
     SwitchGear Promoter luciferase reporter plasmids for TMEM74
     Search ThermoFisher Antibodies for TMEM74
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM74
     Browse compounds at ApexBio
     Search Addgene for plasmids for TMEM74
      Search eBioscience for proteins for TMEM74
      Search eBioscience for elisas for TMEM74
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for TMEM74
     antibodies-online antibodies for TMEM74 (16 products)
     antibodies-online kits for TMEM74 (4 products)
     antibodies-online peptides for TMEM74
      Search antibodies-online for proteins for TMEM74
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TMEM74 gene at Home site.
    Version: 3.12.258 10 Dec 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4