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TMEM68 Gene

protein-coding   GIFtS: 45
GCID: GC08M056651

Transmembrane Protein 68

  Search for TMEM68
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Protein 681 2

External Ids:    HGNC: 265101   Entrez Gene: 1376952   Ensembl: ENSG000001679047   UniProtKB: Q96MH63   

Export aliases for TMEM68 gene to outside databases

Previous GC identifers: GC08M056814 GC08M052119


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEM68 Gene:
TMEM68 (transmembrane protein 68) is a protein-coding gene. GO annotations related to this gene include transferase activity, transferring acyl groups.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000008.11  NT_008183.20  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM68 gene promoter:
         COUP-TF1   TBP   POU3F1   COUP   HNF-4alpha2   HNF-4alpha1   PPAR-gamma1   COUP-TF   TFIID   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM68 promoter sequence
   Search Chromatin IP Primers for TMEM68

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM68


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q12.1   Ensembl cytogenetic band:  8q12.1   HGNC cytogenetic band: 8q12.1

TMEM68 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM68 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M056651:  view genomic region     (about GC identifiers)

Start:
56,608,983 bp from pter      End:
56,685,966 bp from pter
Size:
76,984 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TMM68_HUMAN, Q96MH6 (See protein sequence)
Recommended Name: Transmembrane protein 68  
Size: 324 amino acids; 37425 Da
Secondary accessions: Q658X6 Q8WUD2
Alternative splicing: 3 isoforms:  Q96MH6-1   Q96MH6-2   Q96MH6-3   

Explore the universe of human proteins at neXtProt for TMEM68: NX_Q96MH6

Explore proteomics data for TMEM68 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TMEM68 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001273586.1  NP_001273589.1  NP_001273590.1  NP_689630.1  

    ENSEMBL proteins: 
     ENSP00000428318   ENSP00000395204   ENSP00000335416   ENSP00000428688   ENSP00000431018  
     ENSP00000429026   ENSP00000429667   ENSP00000430542   ENSP00000428236   ENSP00000430838  
     ENSP00000429175   ENSP00000429758   ENSP00000429210   ENSP00000431047   ENSP00000427939  

    TMEM68 Human Recombinant Protein Products:

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    Novus Biologicals TMEM68 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM68

     
    Search eBioscience for Proteins for TMEM68 

    TMEM68 Antibody Products:

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    Abcam antibodies for TMEM68
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    Search ThermoFisher Antibodies for TMEM68
    LSBio Antibodies in human, mouse, rat for TMEM68

    TMEM68 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM68
    Cloud-Clone Corp. CLIAs for TMEM68
    Search eBioscience for ELISAs for TMEM68 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR002123 Plipid/glycerol_acylTrfase

    Graphical View of Domain Structure for InterPro Entry Q96MH6

    ProtoNet protein and cluster: Q96MH6

    1 Blocks protein domain: IPB002123 Phospholipid/glycerol acyltransferase


    Find genes that share domains with TMEM68           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016746transferase activity, transferring acyl groups IEA--
         
    Find genes that share ontologies with TMEM68           About GenesLikeMe


    Phenotypes:
         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Tmem68):
     behavior/neurological  growth/size/body  hematopoietic system  homeostasis/metabolism  integument 

    Find genes that share phenotypes with TMEM68           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM68
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM68

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM68
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM68

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM68:
    hsa-mir-1 (MIRT023909)

    Block miRNA regulation of human, mouse, rat TMEM68 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM68 (see all 21):
    hsa-miR-217 hsa-miR-498 hsa-miR-300 hsa-miR-509-5p hsa-miR-218 hsa-miR-1297 hsa-miR-183* hsa-miR-514b-3p
    SwitchGear 3'UTR luciferase reporter plasmidTMEM68 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM68
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM68

    Gene Editing
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM68 (NM_152417)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM68
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM68

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM68 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM68


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TMM68_HUMAN, Q96MH6: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane2
    cytosol1
    endoplasmic reticulum1
    extracellular1
    mitochondrion1
    nucleus1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TMEM68           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM68
    Interactions:

        Search GeneGlobe Interaction Network for TMEM68

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for TMEM68 (ENSP000003354164) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    KIAA0368ENSP000002593354STRING: ENSP00000259335
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008152metabolic process ----

    Find genes that share ontologies with TMEM68           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM68 (TMM68)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TMEM68 gene (4 alternative transcripts): 
    NM_001286657.1  NM_001286660.1  NM_001286661.1  NM_152417.2  

    Unigene Cluster for TMEM68:

    Transmembrane protein 68
    Hs.420076  [show with all ESTs]
    Unigene Representative Sequence: BC043417
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000522470 ENST00000519460 ENST00000434581(uc003xsg.1) ENST00000334667(uc003xsh.1)
    ENST00000519784 ENST00000517576 ENST00000523073 ENST00000519780 ENST00000522090
    ENST00000520061 ENST00000524121 ENST00000522030 ENST00000523423 ENST00000520414
    ENST00000521229(uc003xsi.1) ENST00000522576 ENST00000523180
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM68 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM68 (see all 21):
    hsa-miR-217 hsa-miR-498 hsa-miR-300 hsa-miR-509-5p hsa-miR-218 hsa-miR-1297 hsa-miR-183* hsa-miR-514b-3p
    SwitchGear 3'UTR luciferase reporter plasmidTMEM68 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM68
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM68
    Clone
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    OriGene clones in human, mouse for TMEM68 (see all 7)
    OriGene ORF clones in mouse, rat for TMEM68
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM68 (NM_152417)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM68
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM68
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM68
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM68
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM68
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM68
      QuantiFast Probe-based Assays in human, mouse, rat TMEM68

    Additional mRNA sequence: 

    AF147306.1 AK056932.1 AK308247.1 AL832935.1 BC020835.1 BC043417.1 BC071636.1 

    13 DOTS entries:

    DT.100752485  DT.99986828  DT.411888  DT.95103538  DT.91637959  DT.100678057  DT.100752487  DT.102842628 
    DT.91755634  DT.95213199  DT.97852970  DT.100674770  DT.91968165 

    Selected AceView cDNA sequences (see all 126):

    BM725986 AI352501 BU581422 AF147306 CN480731 AA846147 NM_152417 AI310529 
    CB306526 BF445835 AI292331 AI364800 BE502417 AI357541 AK056932 AI056009 
    BM471639 AA506442 AA426017 BQ876519 AL832935 BU198370 BI913136 BX951984 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TMEM68 (see all 10)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b · 11c · 11d
    SP1:                                                        -                                                         
    SP2:                    -     -                             -                                                         
    SP3:                                                                                                                  
    SP4:              -     -     -     -     -     -           -                             -                           
    SP5:                          -                                                                                       


    ECgene alternative splicing isoforms for TMEM68

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMEM68 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TMEM68 Expression
    About this image

    TMEM68 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM68 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.420076
        Custom PCR Arrays for TMEM68
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    QuantiFast Probe-based Assays in human, mouse, rat TMEM68
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM68

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TMEM68 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem681 , 5 transmembrane protein 681, 5 90.09(n)1
    93.19(a)1
      4 (1.98 cM)5
    720981  NM_028097.31  NP_082373.11 
     35490415 
    chicken
    (Gallus gallus)
    Aves TMEM681 transmembrane protein 68 69.66(n)
    60.37(a)
      421124  NM_001031021.1  NP_001026192.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 7)
    Uncharacterized protein
    (see all 7)
    39(a)
    37(a)
    (see all 7)
    many → 1
    many → 1
    (see all 7)
    GL343244.1(530364-563244)
    GL343244.1(252474-265876)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tmem681 transmembrane protein 68 69.57(n)
    68.01(a)
      734073  NM_001045749.1  NP_001039214.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc638092 hypothetical protein MGC63809 72.32(n)   393464  BC055249.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG343481 CG34348 54.21(n)
    49.83(a)
      32072  NM_001258691.1  NP_001245620.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y38C1AA.11 Y38C1AA.1 55.71(n)
    48.25(a)
      176836  NM_171239.3  NP_741285.1 


    ENSEMBL Gene Tree for TMEM68 (if available)
    TreeFam Gene Tree for TMEM68 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TMEM68 gene

    Find genes that share paralogs with TMEM68           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for TMEM68
    PGOHUM00000257177 PGOHUM00000262538


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TMEM68 (see all 682)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs109584691,2
    C,F,A,H--52156335(+) AAACCT/CGCAGG 1 -- us2k115Minor allele frequency- C:0.07NS EA WA NA CSA 792
    rs1893523631,2
    --56651025(+) GGTCAC/GCAGTT 1 -- ds50010--------
    rs1813682531,2
    C--56651045(+) CCTGGC/TCAACA 1 -- ds50010--------
    rs132766171,2
    C,A--56651077(+) AAAAAT/CACAAA 1 -- ds50016Minor allele frequency- C:0.09NA WA CSA 11
    rs1859399991,2
    --56651140(+) CCTTCA/GGAAGA 1 -- ds50010--------
    rs1912777881,2
    --56651142(+) TTCAGA/GAGACA 1 -- ds50010--------
    rs1814143171,2
    --56651234(+) CACAGC/TGAGAC 1 -- ds50010--------
    rs113200111,2
    C--56651250(+) CTCAG-/AAAAAA 1 -- ds50012Minor allele frequency- A:0.25NA CSA 4
    rs774940941,2
    C--56651342(+) TTTTAT/CGTACA 1 -- ut313Minor allele frequency- C:0.08CSA WA NA 240
    rs70178761,2
    C,F,A,H--56651634(+) AGTTCG/AAGACC 1 -- ut31 ese37Minor allele frequency- A:0.39NA WA CSA 134

    HapMap Linkage Disequilibrium report for TMEM68 (56608983 - 56685966 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for TMEM68 (see all 25):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2737021CNV Deletion23290073
    esv2112192CNV Deletion18987734
    esv2737020CNV Deletion23290073
    esv2737016CNV Deletion23290073
    esv4861CNV Deletion18987735
    esv1134681CNV Deletion17803354
    esv1187136CNV Deletion17803354
    esv2571467CNV Deletion19546169
    esv2466341CNV Deletion19546169
    esv2239294CNV Deletion18987734

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM68
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM68

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with TMEM68           About GenesLikeMe

    Genetic Association Database (GAD): TMEM68
    Human Genome Epidemiology (HuGE) Navigator: TMEM68 (1 document)

    Export disorders for TMEM68 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMEM68 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TMEM68)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    6. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    9. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (Nat. Biotechnol. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 137695 HGNC: 26510 AceView: FLJ32370 Ensembl:ENSG00000167904 euGenes: HUgn137695
    ECgene: TMEM68 H-InvDB: TMEM68

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for TMEM68 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TMEM68 gene:
    Search GeneIP for patents involving TMEM68

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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