TMEM66 Gene
protein-coding GIFtS: 48
GCID: GC08M029920
|
|
transmembrane protein 66
| |
Aliases for TMEM66 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Transmembrane Protein 661 2 3 | | SOCE-Associated Regulatory Factor2 3 | | Protein FOAP-72 3 | | MGC87211 | | SARAF2 3 | | FOAP-72 | | XTP32 3 | | SARAF Long Isoform2 | | HBV X-Transactivated Gene 3 Protein2 3 | | SARAF Short Isoform2 | | HBV XAg-Transactivated Protein 32 3 | | Store-Operated Calcium Entry-Associated Regulatory Factor2 |
Export aliases for TMEM66 gene to outside databasesPrevious GC identifers: GC08M030042 GC08M028465 |
Summaries for TMEM66 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: SARAF_HUMAN, Q96BY9Function: Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+)overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slowinactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization ofSTIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels,and thus preventing the overload of the cell with excessive Ca(2+) ions Gene Wiki entry for TMEM66
|
Genomic Views for TMEM66 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_167187.1
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the TMEM66 gene promoter: MEF-2A CREB Pax-5 MEF-2 deltaCREB aMEF-2 XBP-1 CUTL1 Cdc5 Other transcription factors
Search SABiosciences Chromatin IP Primers for TMEM66
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM66 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8p12 Ensembl cytogenetic band: 8p12 HGNC cytogenetic band: 8p12TMEM66 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M029920: view genomic region
(about GC identifiers)
Start:
|
29,920,528 bp from pter |
End:
|
29,940,723 bp from pter |
Size:
|
20,196 bases |
Orientation:
|
minus strand |
|
Proteins for TMEM66 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SARAF_HUMAN, Q96BY9 (See
protein sequence)Recommended Name: Store-operated calcium entry-associated regulatory factor precursor Size: 339 amino acids; 36975 Da
Subunit: Interacts with STIM1
Subcellular location: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Translocates to theendoplasmic reticulum-plasma membrane (ER-PM) region in a STIM1-dependent manner following cytosolic Ca(2+) elevation
Subcellular location: Isoform 2: Endoplasmic reticulum membrane; Single-pass type I membrane protein
Sequence caution: Sequence=AAD44487.1; Type=Frameshift; Positions=28;
Secondary accessions: B3KQQ4 B7Z9J1 D3DSU7 H9MHJ8 H9MHJ9 Q53HE8 Q9UNZ3 Q9Y683Alternative splicing: 2 isoforms: Q96BY9-1 Q96BY9-2 Explore the universe of human proteins at neXtProt for TMEM66: NX_Q96BY9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96BY9 TMEM66 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057211.4 ENSEMBL proteins: ENSP00000256255 ENSP00000431005 ENSP00000429538 ENSP00000428963 ENSP00000428323 ENSP00000430477 ENSP00000427769 ENSP00000429630 ENSP00000428245 ENSP00000428832 ENSP00000441351 ENSP00000441723 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
-- | -- | | GO:0030176 | integral to endoplasmic reticulum membrane |
IDA | -- |
TMEM66 for ontologies About GeneDecksing
TMEM66 Antibody Products: Assay Products for TMEM66: |
Protein
Domains / Families for TMEM66 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TMEM66 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96BY9ProtoNet protein and cluster: Q96BY9 UniProtKB/Swiss-Prot: SARAF_HUMAN, Q96BY9Domain: The cytoplasmic C-terminal region mediates interaction with STIM1, while the N-terminal lumenal region mediatesregulation of SOCE activity (PubMed:22464749)Similarity: Belongs to the SARAF family |
Function for TMEM66 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: SARAF_HUMAN, Q96BY9Function: Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+)overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slowinactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization ofSTIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels,and thus preventing the overload of the cell with excessive Ca(2+) ions
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM66 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM66 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TMEM66 (NM_016127) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMEM66 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM66  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM66 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- | | GO:0015279 | store-operated calcium channel activity |
IDA | -- |
TMEM66 for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for TMEM66:
|
Pathways & Interactions for TMEM66 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMEM66
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
 5/19 Interacting proteins for TMEM66 (Q96BY92, 3 ENSP000002562554) via UniProtKB, MINT, STRING, and/or I2D (see all 19)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006816 | calcium ion transport |
-- | -- | | GO:0032235 | negative regulation of calcium ion transport via store-operated calcium channel activity |
-- | -- | | GO:2001256 | regulation of store-operated calcium entry |
IDA | -- |
TMEM66 for ontologies About GeneDecksing
|
Drugs & Compounds for TMEM66 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for TMEM66 Search CenterWatch for drugs/clinical trials and news about TMEM66 / SARAF 
|
Transcripts for TMEM66 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for TMEM66 gene: NM_016127.4 Unigene Cluster for TMEM66: Transmembrane protein 66 Hs.521487 [show with all ESTs]Unigene Representative Sequence: AK02592715 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000256255(uc003xhs.3 uc003xhv.3) ENST00000518174 ENST00000521265 ENST00000520303 ENST00000523127 ENST00000518340 ENST00000518296 ENST00000521934 ENST00000522794 ENST00000522055 ENST00000523761 ENST00000517569 ENST00000521083 ENST00000545648 ENST00000536273
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM66 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM66 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TMEM66 (NM_016127) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMEM66 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM66  |
Additional cDNA sequence: AB028926.1 AF078855.1 AF100748.1 AF490252.1 AK025927.1 AK075340.1 AK094386.1 AK130057.1 AK222632.1 AK295360.1 AK314659.1 AK315956.1 AY359104.1 AY454545.1 BC015012.1 JQ348891.1 JQ348892.1 Z70223.1 24/37 DOTS entries (see all 37): DT.91707800 DT.40116121 DT.95378756 DT.100886075 DT.92048406 DT.100886122 DT.100886086 DT.100806108 DT.100886108 DT.100886121 DT.120650297 DT.95377732 DT.100886125 DT.91707610 DT.92467052 DT.100684282 DT.100886115 DT.92467050 DT.100886093 DT.95290572 DT.100886080 DT.65284525 DT.100681610 DT.120532 24/1079 AceView cDNA sequences (see all 1079): BU151601 AA298313 N48455 AA600845 CR615477 N89883 CR592722 BU160951 CR607306 CR609363 BX364965 CR616524 BI966241 CR622782 BF434330 BX424571 BE327815 BQ218544 CR605556 AW841934 CR609979 AA351106 AL043668 CR608346 GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM66 (see all 11) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | · | 1g | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | · | 9c | · | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 9d | · | 9e | |
| SP1: | |   | |   | |
| SP2: | |   | |   | |
| SP3: | |   | |   | |
| SP4: | |   | |   | |
| SP5: | |   | |   |
ECgene alternative splicing isoforms for TMEM66
|
Expression for TMEM66 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TMEM66 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CAGTTCTCTG
About this image See TMEM66 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for TMEM66
SOURCE GeneReport for Unigene cluster: Hs.521487 UniProtKB/Swiss-Prot: SARAF_HUMAN, Q96BY9Tissue specificity: Highly expressed in macrophages SABiosciences Expression via Pathway-Focused PCR Array including TMEM66:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM66 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMEM66 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM66 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM66 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM66 |
Orthologs for TMEM66 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TMEM66 gene from 6/21 species (see all 21) About this table
ENSEMBL Gene Tree for TMEM66 (if available) TreeFam Gene Tree for TMEM66 (if available)  |
Paralogs for TMEM66 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for TMEM66 gene
TMEM66 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for TMEM66 PGOHUM00000256697
|
Genomic Variants for TMEM66 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 8 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for TMEM66 (29920528 - 29940723 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for TMEM66: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMEM66 |
|
Disorders
/ Diseases for TMEM66 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TMEM66 for disorders About MalaCards
TMEM66 for disorders About GeneDecksing
OMIM gene information: 614768
OMIM disorders: --
Human Genome Epidemiology (HuGE) Navigator: TMEM66 (1 document) Export disorders for TMEM66 gene to outside databases
|
Publications for TMEM66 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TMEM66 gene, integrated from 9 sources (see all 17): (articles sorted by number of sources associating them with TMEM66) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (2000)
- SARAF inactivates the store operated calcium entry machinery to prevent excess calcium refilling. (PubMed id 22464749)1, 2 Palty R.... Reuveny E. (2012)
- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
|
External Searches for TMEM66 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing TMEM66 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TMEM66 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TMEM66 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for TMEM66 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TMEM66 gene: Search GeneIP for patents involving TMEM66
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for TMEM66 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for TMEM66 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM66 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM66 | | OriGene Protein Over-expression Lysate for TMEM66 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for TMEM66 | | OriGene 3'-UTR Clone for TMEM66 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM66 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM66 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for TMEM66 | | OriGene Custom Protein Services for TMEM66 | | OriGene Custom Immunoassay Development | | |
| |  |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TMEM66 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMEM66 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM66 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM66 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM66 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM66 |
| |
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| | | Search Tocris compounds for TMEM66 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | TMEM66 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM66 |
|  |  |  | | | ThermoFisher Antibody for TMEM66 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM66 |
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