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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TMEM63A Gene

protein-coding GIFtS: 50
GCID: GC01M226033

transmembrane protein 63A

(Previous name: KIAA0792 )
(Previous symbol: KIAA0792)

Search for TMEM63A
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Transmembrane Protein 63A¹ ²
KIAA0792¹ ² ³
KIAA0489³

External Ids:	HGNC: 29118¹	Entrez Gene: 9725²	Ensembl: ENSG00000196187⁷	UniProtKB: O94886³

Export aliases for TMEM63A gene to outside databases

Previous GC identifers: GC01M222340 GC01M224099 GC01M196550

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Gene Wiki entry for TMEM63A

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_167186.1

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TMEM63A gene promoter:
Lmo2 RelA NF-kappaB Roaz PPAR-alpha GCNF-1 NF-kappaB1 GCNF-2 Ik-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TMEM63A promoter sequence

Search SABiosciences Chromatin IP Primers for TMEM63A

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM63A

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q42.12 Ensembl cytogenetic band: 1q42.12 HGNC cytogenetic band: 1q42.12

TMEM63A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM63A gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M226033: view genomic region (about GC identifiers)

Start:	226,033,233 bp from pter	End:	226,070,420 bp from pter
Size:	37,188 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TM63A_HUMAN, O94886 (See protein sequence)

Recommended Name: Transmembrane protein 63A

Size: 807 amino acids; 92126 Da

Subcellular location: Lysosome membrane; Multi-pass membrane protein

Sequence caution: Sequence=BAA34512.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Sequence=BAD96654.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAD96664.1;

Type=Erroneous initiation; Note=Translation N-terminally shortened;

Secondary accessions: Q53GI7 Q5TE96 Q8N2U2

Explore the universe of human proteins at neXtProt for TMEM63A: NX_O94886

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O94886

TMEM63A Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_055513.2

ENSEMBL proteins:

ENSP00000355800 ENSP00000409002 ENSP00000445237

Human Recombinant Protein Products for TMEM63A:

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	Novus Biologicals TMEM63A Protein Novus Biologicals TMEM63A Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for TMEM63A

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005765	lysosomal membrane	IDA	--
GO:0016021	integral to membrane	IEA	--

TMEM63A for ontologies About GeneDecksing

TMEM63A Antibody Products:

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	Novus Biologicals TMEM63A Antibody
	Abcam antibodies for TMEM63A
	Uscn Antibodies for TMEM63A
	ThermoFisher Antibody for TMEM63A

Assay Products for TMEM63A:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
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	GenScript Custom Assay Services for TMEM63A
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for TMEM63A

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TMEM63A for domains About GeneDecksing

3 InterPro domains/families:

IPR003864 DUF221

IPR012677 Nucleotide-bd_a/b_plait

IPR026957 TMEM63

Graphical View of Domain Structure for InterPro Entry O94886

ProtoNet protein and cluster: O94886

UniProtKB/Swiss-Prot: TM63A_HUMAN, O94886

Similarity: Belongs to the SPO75/TMEM63 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--

TMEM63A for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for TMEM63A:

Increased gamma-H2AX phosphory

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TMEM63A

miRNA Products:		OriGene 3'-UTR Clone: TMEM63A Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM63A
		4 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM63A:
		hsa-miR-9 hsa-miR-1827 hsa-miR-3612 hsa-miR-650
		SwitchGear 3'UTR luciferase reporter plasmid: TMEM63A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM63A (see all 6) OriGene siRNA: TMEM63A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM63A
		Sirion Biotech Custom design and validation of potent shRNA sequences against TMEM63A

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for TMEM63A
			Sirion Biotech Customized adenovirus for overexpression of TMEM63A Sirion Biotech Customized adenovirus for potent knockdown of TMEM63A

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM63A (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM63A (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: TMEM63A (NM_014698)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM63A
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM63A

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for TMEM63A
		Search LifeMap BioReagents cell lines for TMEM63A
		Sirion Biotech Customized stable knockdown cell line services for TMEM63A Sirion Biotech Customized inducible knockdown cell line services for TMEM63A Sirion Biotech Customized stable overexpressing cell line services for TMEM63A Sirion Biotech Customized inducible overexpressing cell line services for TMEM63A

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM63A

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TMEM63A

1 Interacting protein for TMEM63A (O94886³) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
EEF1D	P29692³	I2D: score=1

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TMEM63A
Search CenterWatch for drugs/clinical trials and news about TMEM63A / TM63A

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TMEM63A gene:

NM_014698.2

Unigene Cluster for TMEM63A:

Transmembrane protein 63A

Hs.119387 [show with all ESTs]

Unigene Representative Sequence: NM_014698

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000366835(uc010pvi.1 uc001hpm.2) ENST00000496025 ENST00000482753

ENST00000487971 ENST00000474478 ENST00000483779 ENST00000436966 ENST00000487817

ENST00000537914

miRNA Products:		OriGene 3'-UTR Clone: TMEM63A Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM63A
		4 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM63A:
		hsa-miR-9 hsa-miR-1827 hsa-miR-3612 hsa-miR-650
		SwitchGear 3'UTR luciferase reporter plasmid: TMEM63A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM63A (see all 6) OriGene siRNA: TMEM63A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM63A
		Sirion Biotech Custom design and validation of potent shRNA sequences against TMEM63A

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM63A (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM63A (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: TMEM63A (NM_014698)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM63A
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM63A

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM63A Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat TMEM63A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM63A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM63A

Additional cDNA sequence:

AB018335.1 AK022465.1 AK022502.1 AK093860.1 AK222934.1 AK222944.1 BC030245.1 BC113811.1

22 DOTS entries:

DT.100809681 DT.121385902 DT.91753085 DT.100646017 DT.313923 DT.433508 DT.75125328 DT.91753082

DT.99958517 DT.100776637 DT.95272203 DT.100776636 DT.97835932 DT.121385814 DT.121385803 DT.121385834

DT.121385857 DT.121385961 DT.95177846 DT.450530 DT.92040653 DT.97760262

24/230 AceView cDNA sequences (see all 230):

BF198037 AI985066 AI248404 BM786323 CA417857 BU542717 AJ705844 CD643051

BM874598 AB018335 AI052158 BQ896620 BP380711 BQ944516 BI031100 AA357762

CK430404 BU752102 BF512395 BQ898575 BG479230 BM873627 BX506091 AA747288

GeneLoc Exon Structure

5/18 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM63A (see all 18) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3	^	4a	·	4b	·	4c	^	5a	·	5b	^	6a	·	6b	·	6c	^	7	^	8a	·	8b	·	8c	^	9a	·	9b	·	9c	^	10	^	11	^	12	^	13	^	14a	·
SP1:
SP2:
SP3:									-		-								-		-										-										-
SP4:									-		-		-						-		-																				-
SP5:									-		-								-		-																				-

ExUns:	14b	^	15a	·	15b	^	16a	·	16b	^	17a	·	17b	^	18a	·	18b	^	19	^	20a	·	20b	^	21	^	22a	·	22b	^	23	^	24	^	25	^	26	^	27	^	28	^	29
SP1:
SP2:													-
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for TMEM63A

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TMEM63A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCACTGAGTT

About this image

TMEM63A expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See TMEM63A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TMEM63A

SOURCE GeneReport for Unigene cluster: Hs.119387

SABiosciences Custom PCR Arrays for TMEM63A

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM63A Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat TMEM63A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM63A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM63A

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM63A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for TMEM63A gene from 7/28 species (see all 28) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	TMEM63A¹	transmembrane protein 63A	68.01(n) 69.32(a)		421319 XM_419384.3 XP_419384.3
lizard (Anolis carolinensis)	Reptilia	TMEM63A⁶	--	67(a)	1 ↔ 1	1(251657340-251696659)
African clawed frog (Xenopus laevis)	Amphibia	BJ033875.1²	--	80.07(n)		BJ033875.1
zebrafish (Danio rerio)	Actinopterygii	tmem63a¹	transmembrane protein 63A	62.17(n) 57.58(a)		557924 NM_001089378.1 NP_001082847.1
fruit fly (Drosophila melanogaster)	Insecta	CG11210¹	CG11210	47.65(n) 35.56(a)		35779 NM_136507.2 NP_610351.1
thale cress (Arabidopsis thaliana)	eudicotyledons	AT1G32090¹	early-responsive to dehydration stress protein (ERD4)	39.83(n) 24.8(a)		840101 NM_102943.5 NP_174489.1
rice (Oryza sativa)	Liliopsida	Os10g0579100¹	hypothetical protein	41.79(n) 25(a)		4349511 NM_001072036.1 NP_001065504.1

ENSEMBL Gene Tree for TMEM63A (if available)
TreeFam Gene Tree for TMEM63A (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TMEM63A gene

TMEM63B² TMEM63C²

2 SIMAP similar genes for TMEM63A using alignment to 2 protein entries: TM63A_HUMAN (see all proteins):

TMEM63B TMEM63C

TMEM63A for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs1054393^1,2		--	226033795(-)	`TGCCCT/GTGAGC`	1	--	ut3¹ ese³		2		MN NA	186
rs190289692^1,2		--	226033867(+)	`GGCTCC/TGAGGA`	1	--	ut3¹		0	--	--	--	--
rs148952946^1,2		--	226033872(+)	`CGAGGA/CGGCCC`	1	--	ut3¹		0	--	--	--	--
rs77286407^1,2		--	226033886(+)	`GCACTG/ACCCAC`	1	--	ut3¹		1		EA	120
rs45505095^1,2	C,F	--	226033922(+)	`GAGGGG/TGTGAG`	1	--	ut3¹		1		NS	164
rs2740174^1,2	C,F,H	--	226033969(+)	`CACTCA/GGCCCT`	1	--	ut3¹ ese³		19		EA NS NA WA	3604
rs41310555^1,2		--	226034182(+)	`TTACTC/TCTGGA`	1	--	ut3¹		0	--	--	--	--
rs143793861^1,2		--	226034253(+)	`CCAGCA/GGGACC`	1	--	ut3¹		0	--	--	--	--
rs147251194^1,2		--	226034360(+)	`CTCCCA/GGACTC`	1	--	ut3¹		0	--	--	--	--
rs45518131^1,2	C,F	--	226034375(+)	`GTTTGG/AGGGGC`	1	--	ut3¹		2		NS WA	290

HapMap Linkage Disequilibrium report for TMEM63A (226033233 - 226070420 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for TMEM63A
2 CNVs: 48250 5555

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMEM63A

DNA2.0 Custom Variant and Variant Library Synthesis for TMEM63A

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TMEM63A for disorders About MalaCards

TMEM63A for disorders About GeneDecksing

Human Genome Epidemiology (HuGE) Navigator: TMEM63A (3 documents)

Export disorders for TMEM63A gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TMEM63A gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with TMEM63A)

Utopia: connect your pdf to the dynamic
world of online information

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)^{1, 2, 3} Nagase T.... Ohara O. (1998)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. (PubMed id 9455484)^{1, 3} Seki N.... Ohara O. (1997)
The proteome of lysosomes. (PubMed id 20957757)² Schroeder B.A.... Saftig P. (2010)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 9725	HGNC: 29118	AceView: KIAA0792	Ensembl:ENSG00000196187	euGenes: HUgn9725
ECgene: TMEM63A	H-InvDB: TMEM63A

(According to HUGE)
About This Section

HUGE: KIAA0792 KIAA0489

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TMEM63A	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TMEM63A gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TMEM63A gene:
Search GeneIP for patents involving TMEM63A

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	Regulatory tfbs in TMEM63A promoter
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

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ThermoFisher Antibody for TMEM63A

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM63A

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TMEM63A

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GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

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TMEM63A Gene

transmembrane protein 63A

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TMEM63A Gene

transmembrane protein 63A

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External Searches for TMEM63A gene

Genome Databases showing TMEM63A gene

Other Databases showing TMEM63A gene

Specialized Databases showing TMEM63A gene

Intellectual Propertyfor TMEM63A gene

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Summaries
for TMEM63A gene

Genomic Views
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Families
for TMEM63A gene

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for TMEM63A gene

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for TMEM63A gene

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for TMEM63A gene

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for TMEM63A gene

Expression
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Orthologs
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Paralogs
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Genomic Variants
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Disorders / Diseases
for TMEM63A gene

Publications
for TMEM63A gene

Intellectual Property
for TMEM63A gene

Products
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