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Aliases for TMEM62 Gene

Aliases for TMEM62 Gene

  • Transmembrane Protein 62 2 3

External Ids for TMEM62 Gene

Previous GeneCards Identifiers for TMEM62 Gene

  • GC15P041214
  • GC15P043425
  • GC15P020273
  • GC15P043415

Summaries for TMEM62 Gene

GeneCards Summary for TMEM62 Gene

TMEM62 is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM62 Gene

Genomics for TMEM62 Gene

Regulatory Elements for TMEM62 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMEM62 Gene

Start:
43,123,279 bp from pter
End:
43,185,147 bp from pter
Size:
61,869 bases
Orientation:
Plus strand

Genomic View for TMEM62 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM62 Gene

Proteins for TMEM62 Gene

  • Protein details for TMEM62 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q0P6H9-TMM62_HUMAN
    Recommended name:
    Transmembrane protein 62
    Protein Accession:
    Q0P6H9
    Secondary Accessions:
    • Q6I9Y5
    • Q9H5J6

    Protein attributes for TMEM62 Gene

    Size:
    643 amino acids
    Molecular mass:
    73133 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB15630.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for TMEM62 Gene

Proteomics data for TMEM62 Gene at MOPED

Post-translational modifications for TMEM62 Gene

  • Glycosylation at Asn180, Asn467, and Asn626
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for TMEM62 Gene

Domains for TMEM62 Gene

Protein Domains for TMEM62 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM62 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM62: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM62 Gene

Function for TMEM62 Gene

Gene Ontology (GO) - Molecular Function for TMEM62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005509 calcium ion binding --
genes like me logo Genes that share ontologies with TMEM62: view

Animal Model Products

CRISPR Products

miRNA for TMEM62 Gene

miRTarBase miRNAs that target TMEM62

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM62 Gene

Localization for TMEM62 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM62 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM62 Gene COMPARTMENTS Subcellular localization image for TMEM62 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for TMEM62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM62: view

Pathways for TMEM62 Gene

SuperPathways for TMEM62 Gene

No Data Available

Interacting Proteins for TMEM62 Gene

Selected Interacting proteins: Q0P6H9-TMM62_HUMAN for TMEM62 Gene via I2D

Gene Ontology (GO) - Biological Process for TMEM62 Gene

None

No data available for Pathways by source for TMEM62 Gene

Transcripts for TMEM62 Gene

Unigene Clusters for TMEM62 Gene

Transmembrane protein 62:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM62

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM62 Gene

No ASD Table

Relevant External Links for TMEM62 Gene

GeneLoc Exon Structure for
TMEM62
ECgene alternative splicing isoforms for
TMEM62

Expression for TMEM62 Gene

mRNA expression in normal human tissues for TMEM62 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for TMEM62 Gene

SOURCE GeneReport for Unigene cluster for TMEM62 Gene Hs.511175

genes like me logo Genes that share expressions with TMEM62: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TMEM62 Gene

Orthologs for TMEM62 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TMEM62 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM62 35
  • 99.74 (n)
  • 99.84 (a)
TMEM62 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM62 35
  • 88.7 (n)
  • 83.83 (a)
TMEM62 36
  • 84 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM62 35
  • 89.99 (n)
  • 88.18 (a)
TMEM62 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem62 35
  • 85.43 (n)
  • 83.2 (a)
Tmem62 16
Tmem62 36
  • 83 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM62 36
  • 60 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM62 36
  • 61 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem62 35
  • 84.55 (n)
  • 82.74 (a)
chicken
(Gallus gallus)
Aves TMEM62 35
  • 69.34 (n)
  • 65.59 (a)
TMEM62 36
  • 63 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM62 36
  • 63 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem62 35
  • 62.67 (n)
  • 60.1 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.26190 35
tmem62 35
  • 61.51 (n)
  • 60.17 (a)
tmem62 36
  • 56 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010204 35
  • 47.85 (n)
  • 41.94 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G03305 35
  • 43.94 (n)
  • 30.39 (a)
rice
(Oryza sativa)
Liliopsida Os01g0894000 35
  • 46.73 (n)
  • 35.19 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 35 (a)
OneToOne
Species with no ortholog for TMEM62:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM62 Gene

ENSEMBL:
Gene Tree for TMEM62 (if available)
TreeFam:
Gene Tree for TMEM62 (if available)

Paralogs for TMEM62 Gene

No data available for Paralogs for TMEM62 Gene

Variants for TMEM62 Gene

Sequence variations from dbSNP and Humsavar for TMEM62 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs476342 -- 43,181,709(-) GCCTG(C/G)CCAAC intron-variant
rs574856 -- 43,168,636(+) tccac(A/G)agagg intron-variant
rs1464344 -- 43,135,383(-) GCTCA(C/T)GAGAC intron-variant
rs1464345 -- 43,134,961(-) TGCTT(C/T)AATAA intron-variant
rs1520518 -- 43,159,443(+) ccatg(A/G)attca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM62 Gene

Variant ID Type Subtype PubMed ID
nsv525461 CNV Loss 19592680
nsv515876 CNV Gain+Loss 19592680
dgv2368n71 CNV Loss 21882294
nsv94791 CNV Loss 16902084
esv2678276 CNV Deletion 23128226

Relevant External Links for TMEM62 Gene

HapMap Linkage Disequilibrium report
TMEM62

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM62 Gene

Disorders for TMEM62 Gene

Relevant External Links for TMEM62

Genetic Association Database (GAD)
TMEM62
genes like me logo Genes that share disorders with TMEM62: view

No data available for UniProtKB/Swiss-Prot for TMEM62 Gene

Publications for TMEM62 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  4. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PMID: 19159218) Chen R. … Zou H. (J. Proteome Res. 2009) 4
  5. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PMID: 8125298) Maruyama K. … Sugano S. (Gene 1994) 3

Products for TMEM62 Gene

Sources for TMEM62 Gene

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